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Conserved domains on  [gi|491113990|ref|WP_004972448|]
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MULTISPECIES: AraC family transcriptional regulator [Acinetobacter]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 12117701)

AraC family transcriptional regulator containing an AraC family HTH domain and an N-terminal arabinose binding domain, may regulate the expression of genes with diverse biological functions including metabolism, stress response, and virulence.

Gene Ontology:  GO:0003700

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Arabinose_bd pfam12625
Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial ...
 22-204 5.90e-52

Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].


:

Pssm-ID: 432679  Cd Length: 185  Bit Score: 169.75  E-value: 5.90e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990   22 GMDVETLLSHVGIEAELLRQPKARISPEQYTRFIKMLWMVTQDEHVGFDS-QPRRLGTFAIMCQLVIHAKTLGDALELSS 100
Cdd:pfam12625   1 GLDPAALLRRAGLDPALLADPDARVPLDQYLRLWEAAARELGDPALGLRLgRRLRPGSLGLLGYAALSSPTLGEALDRLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990  101 QFYKLFGDDWSVTL-ERDKHEARLVPSIPQAM-DPDHFITESMLMIWHGLASWLIERRLPLERVHFGYPRPAHADEYDAL 178
Cdd:pfam12625  81 RYLRLLSDALELRLeEGEGGLARLRLDVRPIPgRRRDFLLELALAALLRLARWLLGRRLPPLRVEFPHPAPADAAEYERL 160

                         170       180
                  ....*....|....*....|....*.
gi 491113990  179 FFAPVmQFDMPRTEITFAADYLDLPI 204
Cdd:pfam12625 161 FGCPV-RFGAPRNALVFDAADLDRPL 185
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
249-330 1.52e-21

helix_turn_helix, arabinose operon control protein;


:

Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 87.22  E-value: 1.52e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990   249 PTLNDVASMLYLSPQTLRRRLAAE-GKSYQGVKDALRRDAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPG 327
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 491113990   328 LYR 330
Cdd:smart00342  82 EYR 84
 
Name Accession Description Interval E-value
Arabinose_bd pfam12625
Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial ...
 22-204 5.90e-52

Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].


Pssm-ID: 432679  Cd Length: 185  Bit Score: 169.75  E-value: 5.90e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990   22 GMDVETLLSHVGIEAELLRQPKARISPEQYTRFIKMLWMVTQDEHVGFDS-QPRRLGTFAIMCQLVIHAKTLGDALELSS 100
Cdd:pfam12625   1 GLDPAALLRRAGLDPALLADPDARVPLDQYLRLWEAAARELGDPALGLRLgRRLRPGSLGLLGYAALSSPTLGEALDRLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990  101 QFYKLFGDDWSVTL-ERDKHEARLVPSIPQAM-DPDHFITESMLMIWHGLASWLIERRLPLERVHFGYPRPAHADEYDAL 178
Cdd:pfam12625  81 RYLRLLSDALELRLeEGEGGLARLRLDVRPIPgRRRDFLLELALAALLRLARWLLGRRLPPLRVEFPHPAPADAAEYERL 160

                         170       180
                  ....*....|....*....|....*.
gi 491113990  179 FFAPVmQFDMPRTEITFAADYLDLPI 204
Cdd:pfam12625 161 FGCPV-RFGAPRNALVFDAADLDRPL 185
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
249-330 1.52e-21

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 87.22  E-value: 1.52e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990   249 PTLNDVASMLYLSPQTLRRRLAAE-GKSYQGVKDALRRDAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPG 327
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 491113990   328 LYR 330
Cdd:smart00342  82 EYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
102-333 1.94e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 91.77  E-value: 1.94e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 102 FYKLFGDDWSVTLERDKHEARLVPSIPQAMDPDHFITESMLMIWHGLASWLIERRLPLERVHFGYPRPAHADEYDALFFA 181
Cdd:COG2207   22 LLLLLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLL 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 182 PVMQFDMPRTEITFAADYLDLPIRQTQETLDEFLKTAPAQLLVKFKNTNSLTSRIRDVLKSQIGEEMPTLNDVASMLYLS 261
Cdd:COG2207  102 LLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLS 181

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491113990 262 PQTLRRRLAAE-GKSYQGVKDALRRDAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPGLYRQLH 333
Cdd:COG2207  182 PRTLSRLFKEEtGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRL 254
HTH_18 pfam12833
Helix-turn-helix domain;
254-331 1.04e-16

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 73.78  E-value: 1.04e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990  254 VASMLYLSPQTLRRRLAAE-GKSYQGVKDALRRDAAIHLLL-NPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPGLYRQ 331
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLeDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 219-334 2.65e-12

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 66.72  E-value: 2.65e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 219 PAQLLVKFKNTNSLTSRIRDVLKSQIGEEMpTLNDVASMLYLSPQTLRRRLAAE-GKS----YQgvkdALRRDAAIHLLL 293
Cdd:COG4977  198 FSPLLVPLGHRDPRLARAQAWMEANLEEPL-SVDELARRAGMSPRTLERRFRAAtGTTparyLQ----RLRLERARRLLE 272

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 491113990 294 NPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPGLYRQLHG 334
Cdd:COG4977  273 TTDLSIEEIAAACGFGSASHFRRAFRRRFGVSPSAYRRRFR 313
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 211-326 1.06e-09

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 58.54  E-value: 1.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 211 LDEFLKTAPAQLLVKFKNTNSLTSRIRDVLKSQIGEEMpTLNDVASMLYLSPQTLRRRLAAEGKSYQGVKDALRRDAAIH 290
Cdd:PRK15186 161 LSEFIYEPEAFALFRELSQNTLAENIYNIIISDISRKW-ALKDISDSLYMSCSTLKRKLKQENTSFSEVYLNARMNKATK 239

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 491113990 291 LLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVTP 326
Cdd:PRK15186 240 LLRNSEYNITRVAYMCGYDSASYFTCVFKKHFKTTP 275
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
168-332 3.33e-04

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 41.96  E-value: 3.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 168 RPAHADEYDALFFApvmQFDMPRTEITFAADylDLPIRQTQETLDEFLKTAPAQL-----LVKFKNTNSLTSRI-RDVLK 241
Cdd:PRK13502 140 RDPLANEMAELLFG---QLVMTLKRHRYATD--DLPATSRETLLDKLITALANSLecpfaLDAFCQQEQCSERVlRQQFR 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 242 SQIGEempTLNdvasmlylspQTLRRrlaaegksyqgvkdaLRRDAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKW 321
Cdd:PRK13502 215 AQTGM---TIN----------QYLRQ---------------VRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRE 266

                        170
                 ....*....|.
gi 491113990 322 TGVTPGLYRQL 332
Cdd:PRK13502 267 TGMTPSQWRHL 277
 
Name Accession Description Interval E-value
Arabinose_bd pfam12625
Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial ...
 22-204 5.90e-52

Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].


Pssm-ID: 432679  Cd Length: 185  Bit Score: 169.75  E-value: 5.90e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990   22 GMDVETLLSHVGIEAELLRQPKARISPEQYTRFIKMLWMVTQDEHVGFDS-QPRRLGTFAIMCQLVIHAKTLGDALELSS 100
Cdd:pfam12625   1 GLDPAALLRRAGLDPALLADPDARVPLDQYLRLWEAAARELGDPALGLRLgRRLRPGSLGLLGYAALSSPTLGEALDRLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990  101 QFYKLFGDDWSVTL-ERDKHEARLVPSIPQAM-DPDHFITESMLMIWHGLASWLIERRLPLERVHFGYPRPAHADEYDAL 178
Cdd:pfam12625  81 RYLRLLSDALELRLeEGEGGLARLRLDVRPIPgRRRDFLLELALAALLRLARWLLGRRLPPLRVEFPHPAPADAAEYERL 160

                         170       180
                  ....*....|....*....|....*.
gi 491113990  179 FFAPVmQFDMPRTEITFAADYLDLPI 204
Cdd:pfam12625 161 FGCPV-RFGAPRNALVFDAADLDRPL 185
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
249-330 1.52e-21

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 87.22  E-value: 1.52e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990   249 PTLNDVASMLYLSPQTLRRRLAAE-GKSYQGVKDALRRDAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPG 327
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 491113990   328 LYR 330
Cdd:smart00342  82 EYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
102-333 1.94e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 91.77  E-value: 1.94e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 102 FYKLFGDDWSVTLERDKHEARLVPSIPQAMDPDHFITESMLMIWHGLASWLIERRLPLERVHFGYPRPAHADEYDALFFA 181
Cdd:COG2207   22 LLLLLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLL 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 182 PVMQFDMPRTEITFAADYLDLPIRQTQETLDEFLKTAPAQLLVKFKNTNSLTSRIRDVLKSQIGEEMPTLNDVASMLYLS 261
Cdd:COG2207  102 LLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLS 181

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491113990 262 PQTLRRRLAAE-GKSYQGVKDALRRDAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPGLYRQLH 333
Cdd:COG2207  182 PRTLSRLFKEEtGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRL 254
HTH_18 pfam12833
Helix-turn-helix domain;
254-331 1.04e-16

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 73.78  E-value: 1.04e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990  254 VASMLYLSPQTLRRRLAAE-GKSYQGVKDALRRDAAIHLLL-NPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPGLYRQ 331
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLeDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 219-334 2.65e-12

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 66.72  E-value: 2.65e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 219 PAQLLVKFKNTNSLTSRIRDVLKSQIGEEMpTLNDVASMLYLSPQTLRRRLAAE-GKS----YQgvkdALRRDAAIHLLL 293
Cdd:COG4977  198 FSPLLVPLGHRDPRLARAQAWMEANLEEPL-SVDELARRAGMSPRTLERRFRAAtGTTparyLQ----RLRLERARRLLE 272

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 491113990 294 NPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPGLYRQLHG 334
Cdd:COG4977  273 TTDLSIEEIAAACGFGSASHFRRAFRRRFGVSPSAYRRRFR 313
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 246-331 7.13e-10

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 59.68  E-value: 7.13e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 246 EEMPTLNDVASMLYLSPQTLRRRLAAE-GKSYQGVKDALRRDAAIHLLlNPELTLEDVAQQVGFSETSTFHRAFKKWTGV 324
Cdd:COG2169   98 EDRPSLEDLAARLGLSPRHLRRLFKAHtGVTPKAYARARRLLRARQLL-QTGLSVTDAAYAAGFGSLSRFYEAFKKLLGM 176


                 ....*..
gi 491113990 325 TPGLYRQ 331
Cdd:COG2169  177 TPSAYRR 183
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 211-326 1.06e-09

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 58.54  E-value: 1.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 211 LDEFLKTAPAQLLVKFKNTNSLTSRIRDVLKSQIGEEMpTLNDVASMLYLSPQTLRRRLAAEGKSYQGVKDALRRDAAIH 290
Cdd:PRK15186 161 LSEFIYEPEAFALFRELSQNTLAENIYNIIISDISRKW-ALKDISDSLYMSCSTLKRKLKQENTSFSEVYLNARMNKATK 239

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 491113990 291 LLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVTP 326
Cdd:PRK15186 240 LLRNSEYNITRVAYMCGYDSASYFTCVFKKHFKTTP 275
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 289-331 4.60e-09

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 51.39  E-value: 4.60e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 491113990  289 IHLLLNPELTLEDVAQQVGFSEtSTFHRAFKKWTGVTPGLYRQ 331
Cdd:pfam00165   1 LRENLSTNLTIADIADELGFSR-SYFSRLFKKYTGVTPSQYRH 42
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 231-329 6.42e-09

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 56.54  E-value: 6.42e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 231 SLTSRIRDVLKSQIGEEMpTLNDVASMLYLSPQTLRRRLAAEGKSYQGVKDALRRDAAIHLLLNPELTLEDVAQQVGFSE 310
Cdd:PRK15185 206 TLKERVYNIISSSPSRQW-KLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAKLLRIGNHNVNAVALKCGYDS 284

                         90
                 ....*....|....*....
gi 491113990 311 TSTFHRAFKKWTGVTPGLY 329
Cdd:PRK15185 285 TSYFIQCFKKYFKTTPSTF 303
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 232-336 2.02e-08

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 54.55  E-value: 2.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 232 LTSRIRDVLKSQIGEEMpTLNDVASMLYLSPQTLRRRLAAEGKSYQGVKDALRRDAAIHLLLNPELTLEDVAQQVGFSET 311
Cdd:PRK09978 143 MRTRVCTVINNNIAHEW-TLARIASELLMSPSLLKKKLREEETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGYHSV 221

                         90       100
                 ....*....|....*....|....*
gi 491113990 312 STFHRAFKKWTGVTPGLYRQLHGYH 336
Cdd:PRK09978 222 SYFIYVFRNYYGMTPTEYQERSAQG 246
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
135-331 1.37e-06

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 49.01  E-value: 1.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 135 HFITESMLMIWHGLASWLIERRLPLERVHFGYPRPAHADEYDALFFAPVMQFDMPRTEITFAADYLDLPIRQTQETLDEF 214
Cdd:COG2207    7 LLLLLLLLALLLLLLLLLLLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 215 LKTAPAQLLVKFKNTNSLTSRIRDVLKSQIGEEMPTLNDVASMLYLSPQTLRRRLAAEGKSYQGVKDALRRDAAIHLLLN 294
Cdd:COG2207   87 ALLLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 166

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 491113990 295 PELTLEDVAQQVGFSEtSTFHRAFKKWTGVTPGLYRQ 331
Cdd:COG2207  167 LLLTLEELARELGLSP-RTLSRLFKEETGTSPKQYLR 202
ftrA PRK09393
transcriptional activator FtrA; Provisional
 234-330 5.28e-06

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 47.65  E-value: 5.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 234 SRIRDVLKSQIGEEMpTLNDVASMLYLSPQTLRRRL-AAEGKSYQG--VKDALRRdaAIHLLLNPELTLEDVAQQVGFSE 310
Cdd:PRK09393 221 GPLIDWMRAHLAEPH-TVASLAARAAMSPRTFLRRFeAATGMTPAEwlLRERLAR--ARDLLESSALSIDQIAERAGFGS 297

                         90       100
                 ....*....|....*....|
gi 491113990 311 TSTFHRAFKKWTGVTPGLYR 330
Cdd:PRK09393 298 EESLRHHFRRRAATSPAAYR 317
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
296-331 1.65e-05

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 42.54  E-value: 1.65e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 491113990   296 ELTLEDVAQQVGFSEtSTFHRAFKKWTGVTPGLYRQ 331
Cdd:smart00342   1 PLTLEDLAEALGVSP-RHLQRLFKKETGTTPKQYLR 35
PRK09940 PRK09940
transcriptional regulator YdeO; Provisional
 231-326 1.17e-04

transcriptional regulator YdeO; Provisional


Pssm-ID: 182157 [Multi-domain]  Cd Length: 253  Bit Score: 43.15  E-value: 1.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 231 SLTSRIRDVLKSQIGEEMpTLNDVASMLYLSPQTLRRRLAAEGKSYQGVKDALRRDAAIHLLlNPELTLEDVAQQVGFSE 310
Cdd:PRK09940 134 SVSGKVRNIVNMKLAHPW-KLKDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLI-RVEGSVNKIAEQCGYAS 211

                         90
                 ....*....|....*.
gi 491113990 311 TSTFHRAFKKWTGVTP 326
Cdd:PRK09940 212 TSYFIYAFRKHFGNSP 227
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
232-330 2.05e-04

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 42.27  E-value: 2.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 232 LTSRIRDV---LKSQIGEEMpTLNDVASMLYLSPQtlrrRLAAEGKSYQGV-----KDALRRDAAIHLLLNPELTLEDVA 303
Cdd:PRK10572 181 MDPRVREAcqyISDHLASEF-DIESVAQHVCLSPS----RLAHLFRQQLGIsvlrwREDQRISRAKLLLQTTRMPIATIG 255

                         90       100
                 ....*....|....*....|....*..
gi 491113990 304 QQVGFSETSTFHRAFKKWTGVTPGLYR 330
Cdd:PRK10572 256 RNVGYDDQLYFSRVFKKCTGASPSEFR 282
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
168-332 3.33e-04

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 41.96  E-value: 3.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 168 RPAHADEYDALFFApvmQFDMPRTEITFAADylDLPIRQTQETLDEFLKTAPAQL-----LVKFKNTNSLTSRI-RDVLK 241
Cdd:PRK13502 140 RDPLANEMAELLFG---QLVMTLKRHRYATD--DLPATSRETLLDKLITALANSLecpfaLDAFCQQEQCSERVlRQQFR 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 242 SQIGEempTLNdvasmlylspQTLRRrlaaegksyqgvkdaLRRDAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKW 321
Cdd:PRK13502 215 AQTGM---TIN----------QYLRQ---------------VRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRE 266

                        170
                 ....*....|.
gi 491113990 322 TGVTPGLYRQL 332
Cdd:PRK13502 267 TGMTPSQWRHL 277
PRK10371 PRK10371
transcriptional regulator MelR;
250-332 6.89e-04

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 40.96  E-value: 6.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 250 TLNDVASMLYLSPQ----TLRRRLAAEGKSYqgvKDALRRDAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVT 325
Cdd:PRK10371 209 TINDVAEHVKLNANyamgIFQRVMQLTMKQY---ITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYSTFGKYVGMS 285


                 ....*..
gi 491113990 326 PGLYRQL 332
Cdd:PRK10371 286 PQQYRKL 292
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 234-333 7.84e-04

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 40.78  E-value: 7.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 234 SRIRDVLKSQIGEEMPTLNDVASMLYLSPQTLRRRLAAEGKSY-QGVKDA-LRRDAAIhllLNPEL---TLEDVAQQVGF 308
Cdd:PRK09685 200 QKVVALIDQSIQEEILRPEWIAGELGISVRSLYRLFAEQGLVVaQYIRNRrLDRCADD---LRPAAddeKITSIAYKWGF 276

                         90       100
                 ....*....|....*....|....*
gi 491113990 309 SETSTFHRAFKKWTGVTPGLYRQLH 333
Cdd:PRK09685 277 SDSSHFSTAFKQRFGVSPGEYRRKF 301
PRK15044 PRK15044
transcriptional regulator SirC; Provisional
 253-326 9.70e-04

transcriptional regulator SirC; Provisional


Pssm-ID: 185004 [Multi-domain]  Cd Length: 295  Bit Score: 40.40  E-value: 9.70e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491113990 253 DVASMLYLSPQTLRRRLAAEGKSYQGVKDALRRDAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVTP 326
Cdd:PRK15044 213 EVAGKLFMSVSSLKRKLAAEEVSFSKIYLDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITP 286
PRK10296 PRK10296
DNA-binding transcriptional regulator ChbR; Provisional
 202-331 2.64e-03

DNA-binding transcriptional regulator ChbR; Provisional


Pssm-ID: 182362 [Multi-domain]  Cd Length: 278  Bit Score: 38.97  E-value: 2.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 202 LPIRQTQetLDEFLKtapaqlLVKFKNTNsltsRIRDVLKSQIGEEMP-----TLNDVASMLYLSPQTLRRRLAAEGKSY 276
Cdd:PRK10296 135 LNFRETG--LDEFVE------LVTFYVIN----RLRHYREEQVIDDIPqwlkaTVEKMHDKEQFSESALENMVRLSGKSQ 202

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491113990 277 QGVKDALRR---------------DAAIHLLLNPELTLEDVAQQVGFSETSTFHRAFKKWTGVTPGLYRQ 331
Cdd:PRK10296 203 EYLTRATRRyygktpmqiineiriNFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPGSYRK 272
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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