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Conserved domains on  [gi|491118258|ref|WP_004976709|]
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MULTISPECIES: polyprenyl diphosphate synthase [Acinetobacter]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10000255)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates, similar to UPPS that catalyzes chain elongation of FPP by eight IPP to form the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis

Gene Ontology:  GO:0016765|GO:0000287|GO:0002094
PubMed:  22471620

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
6-243 6.57e-138

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


:

Pssm-ID: 439791  Cd Length: 248  Bit Score: 387.49  E-value: 6.57e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   6 DSASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETT 85
Cdd:COG0020   11 DPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREY 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  86 IHEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQI 165
Cdd:COG0020   91 LRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDI 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491118258 166 DTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGKTSEQI 243
Cdd:COG0020  171 DEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
6-243 6.57e-138

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 387.49  E-value: 6.57e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   6 DSASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETT 85
Cdd:COG0020   11 DPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREY 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  86 IHEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQI 165
Cdd:COG0020   91 LRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDI 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491118258 166 DTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGKTSEQI 243
Cdd:COG0020  171 DEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 13-229 2.32e-120

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 341.66  E-value: 2.32e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  13 HVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIHEQLPR 92
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  93 MEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQIDTQLFGQ 172
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 491118258 173 YVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVF 229
Cdd:cd00475  161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDY 217
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 17-237 4.28e-114

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 325.86  E-value: 4.28e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   17 IMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLL-ETTIHEQLPRMEK 95
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLkEEYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   96 FNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVahKIDIEQIDTQLFGQYVS 175
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGK--KLDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491118258  176 LADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFG 237
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 7-243 6.67e-114

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 327.03  E-value: 6.67e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   7 SASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTI 86
Cdd:PRK14836  11 NENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLKAL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  87 HEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQID 166
Cdd:PRK14836  91 DREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPDEID 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491118258 167 TQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGKTSEQI 243
Cdd:PRK14836 171 EALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGKTSAQI 247
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 12-237 1.69e-93

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 274.28  E-value: 1.69e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   12 KHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIHEQLP 91
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   92 RMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQIDTQLFG 171
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491118258  172 QYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFG 237
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
6-243 6.57e-138

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 387.49  E-value: 6.57e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   6 DSASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETT 85
Cdd:COG0020   11 DPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREY 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  86 IHEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQI 165
Cdd:COG0020   91 LRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDI 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491118258 166 DTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGKTSEQI 243
Cdd:COG0020  171 DEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 13-229 2.32e-120

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 341.66  E-value: 2.32e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  13 HVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIHEQLPR 92
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  93 MEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQIDTQLFGQ 172
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 491118258 173 YVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVF 229
Cdd:cd00475  161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDY 217
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 17-237 4.28e-114

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 325.86  E-value: 4.28e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   17 IMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLL-ETTIHEQLPRMEK 95
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLkEEYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   96 FNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVahKIDIEQIDTQLFGQYVS 175
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGK--KLDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491118258  176 LADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFG 237
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 7-243 6.67e-114

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 327.03  E-value: 6.67e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   7 SASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTI 86
Cdd:PRK14836  11 NENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLKAL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  87 HEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQID 166
Cdd:PRK14836  91 DREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPDEID 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491118258 167 TQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGKTSEQI 243
Cdd:PRK14836 171 EALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGKTSAQI 247
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 2-239 1.92e-95

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 279.84  E-value: 1.92e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   2 TTSEDSASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQL 81
Cdd:PRK14830  14 DEELDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  82 LETTIHEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKID 161
Cdd:PRK14830  94 PVEFLDKFVPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGKLN 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491118258 162 IEQIDTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGKT 239
Cdd:PRK14830 174 PEDITEELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRRFGGV 251
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 12-237 1.69e-93

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 274.28  E-value: 1.69e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   12 KHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIHEQLP 91
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   92 RMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQIDTQLFG 171
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491118258  172 QYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFG 237
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14834 PRK14834
isoprenyl transferase;
1-237 3.01e-86

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 256.60  E-value: 3.01e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   1 MTTSEDSASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQ 80
Cdd:PRK14834   5 AKDESDAMSVPRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  81 LLETTIHEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKI 160
Cdd:PRK14834  85 LLRLFIRRDLAELHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEGRL 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491118258 161 DIEQIDTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFG 237
Cdd:PRK14834 165 DPASIDAETISANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRERRFG 241
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 6-238 3.63e-85

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 253.72  E-value: 3.63e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   6 DSASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETT 85
Cdd:PRK14831  16 DPQRLPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFERV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  86 IHEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQI 165
Cdd:PRK14831  96 LRRELEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDPSEI 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491118258 166 DTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGK 238
Cdd:PRK14831 176 DENLFESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFGG 248
PRK14838 PRK14838
isoprenyl transferase;
6-244 5.61e-81

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 242.86  E-value: 5.61e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   6 DSASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETT 85
Cdd:PRK14838   6 DMNRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLDS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  86 IHEQLprMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQI 165
Cdd:PRK14838  86 IEEET--FMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNPEEI 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491118258 166 DTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGKTSEQIQ 244
Cdd:PRK14838 164 TEESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFGKTSEQIS 242
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
9-237 2.43e-78

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 235.86  E-value: 2.43e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   9 SLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIHE 88
Cdd:PRK14833   3 NTLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYLKD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  89 QLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEqIDTQ 168
Cdd:PRK14833  83 ERSTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKLLESPPSHIGELE-SLEE 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491118258 169 LFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFG 237
Cdd:PRK14833 162 EISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
18-240 9.79e-75

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 226.79  E-value: 9.79e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  18 MDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIHEQLPRMEKFN 97
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  98 IALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQIDTQLFGQYVSLA 177
Cdd:PRK10240  81 VRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQHICMH 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491118258 178 DLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGKTS 240
Cdd:PRK10240 161 ELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGTE 223
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 6-238 8.68e-74

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 225.26  E-value: 8.68e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   6 DSASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETT 85
Cdd:PRK14832  14 DPQKIPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFERL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  86 IHEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQI 165
Cdd:PRK14832  94 LRRELAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAV 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491118258 166 DTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGK 238
Cdd:PRK14832 174 NEQLVEQHLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFGQ 246
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 9-238 1.53e-69

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 214.32  E-value: 1.53e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   9 SLPKHVAIIMDGNNRFAKKNQMQKG----EGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLET 84
Cdd:PRK14840  17 SLPRHVAIIMDGNRRWYRKHEQFCQkraiSGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLFNS 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  85 TIHEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQ 164
Cdd:PRK14840  97 QLDSQLPYLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLANKKISSDD 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491118258 165 IDTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGK 238
Cdd:PRK14840 177 ISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQRSRRGGK 250
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
13-237 6.91e-65

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 201.91  E-value: 6.91e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  13 HVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIHEQLPR 92
Cdd:PRK14839  12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAYLRNETER 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  93 MEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAkqiaadvvAHKIDIEQIDTQLFGQ 172
Cdd:PRK14839  92 LARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAA--------AKALGPEGLSREAFSD 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491118258 173 YVSlADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFG 237
Cdd:PRK14839 164 LLT-GDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFG 227
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 9-239 1.59e-62

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 196.16  E-value: 1.59e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   9 SLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIHE 88
Cdd:PRK14829  13 KLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRDVIHR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  89 QLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQIDTQ 168
Cdd:PRK14829  93 RREQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKISGDRVTEK 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491118258 169 LFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGKT 239
Cdd:PRK14829 173 MISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFGGV 243
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 10-237 8.79e-61

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 191.36  E-value: 8.79e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  10 LPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIHEQ 89
Cdd:PRK14841   3 IPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDRE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  90 LPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKiDIEqIDTQL 169
Cdd:PRK14841  83 MELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVSQGK-KIE-LTEET 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491118258 170 FGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFG 237
Cdd:PRK14841 161 FRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFG 228
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 8-237 2.69e-58

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 185.19  E-value: 2.69e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   8 ASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIH 87
Cdd:PRK14842   6 STIPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLLVEFIE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  88 EQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQ-ID 166
Cdd:PRK14842  86 TRLDTIHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEVFLARKAKKVTLEKpLK 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491118258 167 TQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFG 237
Cdd:PRK14842 166 EKEFEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTRKFG 236
PRK14835 PRK14835
isoprenyl transferase;
10-238 1.04e-57

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 184.66  E-value: 1.04e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  10 LPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTIhEQ 89
Cdd:PRK14835  41 LPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNLFEREA-RR 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  90 L---PRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQID 166
Cdd:PRK14835 120 MavdPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLLEAAATGKSPEEVA 199

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491118258 167 TQL----FGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGK 238
Cdd:PRK14835 200 AELtpehISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDYQGRERRFGR 275
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 7-238 5.04e-57

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 183.62  E-value: 5.04e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   7 SASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETTI 86
Cdd:PRK14827  64 ADRLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVV 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  87 HEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDIEQID 166
Cdd:PRK14827 144 RRRRDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGRLNPERIT 223

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491118258 167 TQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGK 238
Cdd:PRK14827 224 ESTIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGS 295
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 6-238 1.16e-56

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 180.79  E-value: 1.16e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   6 DSASLPKHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLETT 85
Cdd:PRK14837   2 NKNSLPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIADY 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  86 IHEQLPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIaadvVAHKIDIEQI 165
Cdd:PRK14837  82 LSSEFNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKKF----LSSGLDLETL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491118258 166 DTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGK 238
Cdd:PRK14837 158 NENVFSKFLDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKRNFGR 230
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 6-238 8.18e-47

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 156.06  E-value: 8.18e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258   6 DSASLPKHVAIIMDGNNRFAKKNQMQK-GEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQLLET 84
Cdd:PRK14828  22 DGAQVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLLDIIED 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  85 TIHEQLPRMekfNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMAQAAKQIAADVVAHKIDI-- 162
Cdd:PRK14828 102 VVRQLAPDG---RWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLTEHKDKGTSIde 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491118258 163 --EQIDTQLFGQYVSLADLPPVDLLIRTGGDFRLSNFLLWQAAYAELYFTQTLWPEFSIEEFDDALAVFGGRERRFGK 238
Cdd:PRK14828 179 laESVTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALRDYSQRERRFGK 256
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 12-222 6.90e-29

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 111.24  E-value: 6.90e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  12 KHVAIIMDGNNRFAKKNQMQKGEGHRSGKDVLDPIVEHCRKKHIQALTVFAFSSENWNRPQFEVDLLMQL-LETTIHEQ- 89
Cdd:PTZ00349  21 KHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLFYLnLLILINEDf 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258  90 -LPRMEKFNIALRFIGDRSRLSPHLRELMLHAEQRTANFNSMTLTIAISYGGMWDMA----------------------Q 146
Cdd:PTZ00349 101 fFKFIKDNKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSRNEMSlckfnpnlyfdtyknlleekkiL 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491118258 147 AAKQIAADVVAH----------------------------------------KIDIEQIDTQLFGQYVSLADLPPVDLLI 186
Cdd:PTZ00349 181 CGSNILTDPIKEgtfaipddedecdyldheleneridldlkfdgdcicgeksFLNEEQIEIVNYHKKLLTSDLPPPNILI 260

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 491118258 187 RTGGDFRLSNFLLWQ-AAYAELYFTQTLWPEFSIEEF 222
Cdd:PTZ00349 261 RTSGEKRLSDFMLYQiSEFTEIYFINEYWPIFNFLQF 297
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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