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molecular chaperone HtpG [Aeromonas salmonicida]
Protein Classification
Hsp90 family chaperone protein ( domain architecture ID 11480452 )
Hsp90 (heat shock protein 90) family chaperone protein, such as molecular chaperone HtpG (high-temperature protein G) that facilitates the folding and conformational changes of a wide array of proteins
List of domain hits
Name
Accession
Description
Interval
E-value
PRK05218
PRK05218 heat shock protein 90; Provisional
6-637
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 1108.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 6 HA ET HG FQ T EVKQLL S LM A HSLYSNKE V FLRELISNASDA A DKLRF K AL S D AS L F E N DG Q L RV R LVV DKE N RTLTISDNG 85
Cdd:PRK05218 2 AM ET GE FQ A EVKQLL H LM I HSLYSNKE I FLRELISNASDA I DKLRF E AL T D PA L Y E G DG D L KI R ISF DKE A RTLTISDNG 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 86 IGMTR DQ VIE H LGTIAKSGT A EF FKN L S GDQ GR DSQLIGQFGVGFYSAF I VADKVTV VS R A AG T A p EQG V Q WES E GEG SF 165
Cdd:PRK05218 82 IGMTR EE VIE N LGTIAKSGT K EF LEK L K GDQ KK DSQLIGQFGVGFYSAF M VADKVTV IT R S AG P A - AEA V R WES D GEG EY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 166 T VADVT KE G RGT DVI LHL RAE E E EFLD D WR L R AVVA KYSD H I S VP VEMF KE gtpdreedgetvvgtpg E W E QV N R A T ALW 245
Cdd:PRK05218 161 T IEEIE KE E RGT EIT LHL KED E D EFLD E WR I R SIIK KYSD F I P VP IKLE KE ----------------- E E E TI N S A S ALW 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 246 TR NPK EI K DEEY Q EFYKH V AHDF E DPL L W G HN R VEG AQ EYT S LLY V P AR APFDL Y NR EQ K H GLKLYV Q RVFIMDDAE QFM 325
Cdd:PRK05218 224 TR SKS EI T DEEY K EFYKH L AHDF D DPL F W I HN N VEG PF EYT G LLY I P KK APFDL F NR DR K G GLKLYV K RVFIMDDAE ELL 303
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 326 P T YLRFVKGV L DS N DLPLNVSREILQ DNK V TVSL RKA CS K R VL TM L A KLAK D D A EKY A KFW S EFG N VLKEG PA ED Y ANRE 405
Cdd:PRK05218 304 P E YLRFVKGV I DS E DLPLNVSREILQ EDR V VKKI RKA IT K K VL DE L E KLAK N D R EKY E KFW K EFG P VLKEG LY ED F ANRE 383
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 406 EI AKLLRFAST AGE gea QT VSL ED YV G RMKEGQ Q KIYYIT A DS FA AAKNSPHLE I F R KKG V EVLL MWERV DE WLM S H L T E 485
Cdd:PRK05218 384 KL AKLLRFAST HEG --- KY VSL AE YV E RMKEGQ K KIYYIT G DS RE AAKNSPHLE L F K KKG I EVLL LTDPI DE FWI S Y L E E 460
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 486 FDGK QLV SV T RG E LDLG D l EDE AS K QAQ EEAE KANAG L V ER V K TS LG EA VK E VR VT HRLTDSP S C I V T D NHG MSTQM I KL 565
Cdd:PRK05218 461 FDGK PFK SV A RG D LDLG K - EDE EE K EEK EEAE EEFKP L L ER L K EA LG DK VK D VR LS HRLTDSP A C L V A D EGD MSTQM E KL 539
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491457439 566 MR AAGQ P VPE Q K Y ILE L NP D H A LVKKL DTIE DEA L F GEWVT LL HE QA Q LAE Q G G L N DPA S FV S R I N R LLL QA 637
Cdd:PRK05218 540 LK AAGQ E VPE S K P ILE I NP N H P LVKKL ADEA DEA K F KDLAE LL YD QA L LAE G G S L E DPA A FV K R L N E LLL KL 611
Name
Accession
Description
Interval
E-value
PRK05218
PRK05218 heat shock protein 90; Provisional
6-637
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 1108.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 6 HA ET HG FQ T EVKQLL S LM A HSLYSNKE V FLRELISNASDA A DKLRF K AL S D AS L F E N DG Q L RV R LVV DKE N RTLTISDNG 85
Cdd:PRK05218 2 AM ET GE FQ A EVKQLL H LM I HSLYSNKE I FLRELISNASDA I DKLRF E AL T D PA L Y E G DG D L KI R ISF DKE A RTLTISDNG 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 86 IGMTR DQ VIE H LGTIAKSGT A EF FKN L S GDQ GR DSQLIGQFGVGFYSAF I VADKVTV VS R A AG T A p EQG V Q WES E GEG SF 165
Cdd:PRK05218 82 IGMTR EE VIE N LGTIAKSGT K EF LEK L K GDQ KK DSQLIGQFGVGFYSAF M VADKVTV IT R S AG P A - AEA V R WES D GEG EY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 166 T VADVT KE G RGT DVI LHL RAE E E EFLD D WR L R AVVA KYSD H I S VP VEMF KE gtpdreedgetvvgtpg E W E QV N R A T ALW 245
Cdd:PRK05218 161 T IEEIE KE E RGT EIT LHL KED E D EFLD E WR I R SIIK KYSD F I P VP IKLE KE ----------------- E E E TI N S A S ALW 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 246 TR NPK EI K DEEY Q EFYKH V AHDF E DPL L W G HN R VEG AQ EYT S LLY V P AR APFDL Y NR EQ K H GLKLYV Q RVFIMDDAE QFM 325
Cdd:PRK05218 224 TR SKS EI T DEEY K EFYKH L AHDF D DPL F W I HN N VEG PF EYT G LLY I P KK APFDL F NR DR K G GLKLYV K RVFIMDDAE ELL 303
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 326 P T YLRFVKGV L DS N DLPLNVSREILQ DNK V TVSL RKA CS K R VL TM L A KLAK D D A EKY A KFW S EFG N VLKEG PA ED Y ANRE 405
Cdd:PRK05218 304 P E YLRFVKGV I DS E DLPLNVSREILQ EDR V VKKI RKA IT K K VL DE L E KLAK N D R EKY E KFW K EFG P VLKEG LY ED F ANRE 383
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 406 EI AKLLRFAST AGE gea QT VSL ED YV G RMKEGQ Q KIYYIT A DS FA AAKNSPHLE I F R KKG V EVLL MWERV DE WLM S H L T E 485
Cdd:PRK05218 384 KL AKLLRFAST HEG --- KY VSL AE YV E RMKEGQ K KIYYIT G DS RE AAKNSPHLE L F K KKG I EVLL LTDPI DE FWI S Y L E E 460
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 486 FDGK QLV SV T RG E LDLG D l EDE AS K QAQ EEAE KANAG L V ER V K TS LG EA VK E VR VT HRLTDSP S C I V T D NHG MSTQM I KL 565
Cdd:PRK05218 461 FDGK PFK SV A RG D LDLG K - EDE EE K EEK EEAE EEFKP L L ER L K EA LG DK VK D VR LS HRLTDSP A C L V A D EGD MSTQM E KL 539
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491457439 566 MR AAGQ P VPE Q K Y ILE L NP D H A LVKKL DTIE DEA L F GEWVT LL HE QA Q LAE Q G G L N DPA S FV S R I N R LLL QA 637
Cdd:PRK05218 540 LK AAGQ E VPE S K P ILE I NP N H P LVKKL ADEA DEA K F KDLAE LL YD QA L LAE G G S L E DPA A FV K R L N E LLL KL 611
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
6-637
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 1061.27
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 6 HA ET HG FQ T EVKQLL S LM A HSLYSNKE V FLRELISNASDA A DKLRF K AL S D AS L F E N DG Q L RV R LV VDKE NR TLTISDNG 85
Cdd:COG0326 2 AK ET GE FQ A EVKQLL D LM I HSLYSNKE I FLRELISNASDA I DKLRF L AL T D PE L K E E DG D L KI R IE VDKE AK TLTISDNG 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 86 IGMTR DQ VIE H LGTIAKSGT A EF FKN L S GDQ GR DS Q LIGQFGVGFYSAF I VADKV T VV S R A AG t APEQG V Q WES E G E G SF 165
Cdd:COG0326 82 IGMTR EE VIE N LGTIAKSGT R EF LEK L K GDQ KK DS D LIGQFGVGFYSAF M VADKV E VV T R S AG - EDAEA V R WES D G D G EY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 166 T VADVT K EG RGT DVI LHL RAEE EEFL DD WRLR AVVA KYSD H I S VP VE M FK E GT pdreedgetvvg TPG E W E QV N R ATALW 245
Cdd:COG0326 161 T IEEAE K AE RGT EIT LHL KEDA EEFL EE WRLR EIIK KYSD F I P VP IK M EG E EE ------------ ETE E D E TI N S ATALW 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 246 TR NPK EI K DEEY Q EFYKH VA HDFEDPL L W G H NR VEG AQ EYT S LLY V P AR APFDLY N R EQ K H G L KLYV Q RVFIMDDAE QFM 325
Cdd:COG0326 229 TR SKS EI T DEEY K EFYKH LF HDFEDPL F W I H LN VEG PF EYT G LLY I P KK APFDLY D R DR K G G I KLYV K RVFIMDDAE DLL 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 326 P T YLRFV K GV L DS N DLPLNVSREILQ DNKVTVSL RKA CS K R VL TM L A KLAK D D A EKY A KFW S EFG N VLKEG PA ED YA NRE 405
Cdd:COG0326 309 P E YLRFV R GV V DS P DLPLNVSREILQ EDRQLKKI RKA IT K K VL DE L E KLAK N D R EKY E KFW K EFG L VLKEG AL ED FK NRE 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 406 E IA K LLRF A ST AGE gea QT V S L ED YV G RMKEGQ Q KIYYIT AD S FA AA KN SPHLEIF RK KG V EVLL MWERV DE W L M SHL T E 485
Cdd:COG0326 389 K IA D LLRF E ST KEG --- GY V T L AE YV E RMKEGQ K KIYYIT GE S RE AA EQ SPHLEIF KA KG I EVLL LTDPI DE F L I SHL E E 465
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 486 FDGK QLV SV TR G E LDL GD LE D eas K QAQ EE A E KANAG L V ER V K TS LG EA VK E VRV TH RLTDSP S C I V T D NHG MS TQ M I K L 565
Cdd:COG0326 466 FDGK KFK SV DS G D LDL DK LE E --- K KES EE E E EEFKP L L ER F K EA LG DK VK D VRV SA RLTDSP A C L V A D EGD MS RR M E K M 542
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491457439 566 MR A A GQ PV PE Q K Y ILE L NP D H A LVKKL DTI EDE A LF GEWVT LL HE QA Q LAE Q G G L N DPA S FV S R I N R LL LQ A 637
Cdd:COG0326 543 LK A M GQ DM PE A K P ILE I NP N H P LVKKL AAE EDE E LF KDLAE LL YD QA L LAE G G L L E DPA A FV K R L N K LL EK A 614
HSP90
pfam00183 Hsp90 protein;
189-637
1.67e-163
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 478.20
E-value: 1.67e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 189 E F L DDWRLRAV V A KYS DH I SV P VEMFK E GT ----------------------- P DR EE DG E -------- T V VG T PG EWE Q 237
Cdd:pfam00183 1 E Y L EEKKIKEL V K KYS EF I NF P IYLWV E KE eevevpdeeeeeeeeeeeeeddd P KV EE ED E eeekkktk K V KE T VW EWE L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 238 V N RATAL WTRNPKE IKD EEY Q EFYK HVAH D F EDPL LWG H NR VEG AQ E YT SLL YV P A RAPFDL YNREQ K H - GL KLYV Q RVF 316
Cdd:pfam00183 81 L N KTKPI WTRNPKE VTE EEY A EFYK SLSK D W EDPL AVK H FS VEG EV E FK SLL FI P K RAPFDL FENKK K K n NI KLYV R RVF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 317 I M DD A E QFM P T YL R FVKGV L DS N DLPLNVSRE I LQ D NK VTVSLR K ACSKRV L T M LAKL A KDD a E K Y A KFW S EFG NV LK E G 396
Cdd:pfam00183 161 I T DD F E DLI P E YL N FVKGV V DS D DLPLNVSRE T LQ Q NK ILKVIK K KLVRKA L D M FKEI A EEK - E D Y K KFW K EFG KN LK L G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 397 PA ED YA NR EEI AKLLRF A S TAGEG E aq TV SL E DYV G RMKEGQ QK IYYIT AD S FAAAK NSP H LE IFR KKG V EVL LMWERV D 476
Cdd:pfam00183 240 II ED SS NR NKL AKLLRF Y S SKSGD E -- LT SL D DYV S RMKEGQ KH IYYIT GE S KEEVE NSP F LE RLK KKG Y EVL YLTDPI D 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 477 E WLMSH L T EFDGK Q LV S V TRGE L D L GDL E D E as K QAQ EE AE K ANAG L VERV K TS LG EA V KE V R V TH RL T DSP SCI VT DNH 556
Cdd:pfam00183 318 E YAVQQ L K EFDGK K LV N V AKEG L E L EED E E E -- K KKD EE LK K EFEP L TKWL K DV LG DK V EK V V V SN RL V DSP CVL VT SQY 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 557 G M S TQ M IKL M R A - A GQPVP ------ EQ K YI LE L NP D H ALV K K L ---- DTIE D EALFGEWVT LL H E Q A Q L AEQGG L N DPAS 625
Cdd:pfam00183 396 G W S AN M ERI M K A q A LRKDS smssym SS K KT LE I NP R H PII K E L lkrv EADK D DKTAKDLAL LL Y E T A L L RSGFS L E DPAS 475
490
....*....|..
gi 491457439 626 F V SRI N R L L LQA 637
Cdd:pfam00183 476 F A SRI Y R M L KLG 487
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
17-207
4.59e-103
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 310.61
E-value: 4.59e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 17 K QLL S L MA HSLYSNKE V FLRELISNASDA A DKLR FKA L S D A SL FEN D GQ L RV R LVV DKENRTLTISD N GIGMT RDQV I EH 96
Cdd:cd16927 1 N QLL D L II HSLYSNKE I FLRELISNASDA L DKLR YLS L T D P SL LDD D PE L EI R ISP DKENRTLTISD T GIGMT KEEL I NN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 97 LGTIA K SGT AE F FKN L SGDQG r DS Q LIGQFGVGFYSAF I VADKVTV VSRA AG ta PEQ G VQ WES E G E GS F T VADVTK E - GR 175
Cdd:cd16927 81 LGTIA R SGT KA F LEA L QEGAK - DS D LIGQFGVGFYSAF M VADKVTV TTKS AG -- DDE G YR WES D G G GS Y T IEEAEG E l GR 157
170 180 190
....*....|....*....|....*....|..
gi 491457439 176 GT DVI LHL RAEEE EFL DDW R LRAV V A KYSD H I 207
Cdd:cd16927 158 GT KIT LHL KEDAK EFL EEA R IKEL V K KYSD F I 189
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
30-186
1.05e-11
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 61.90
E-value: 1.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 30 NKEVF LR ELI SN AS D A A D K LRFK alsdaslfen D G QLR V R L VV D KENRTL T IS DNG I G MTRDQ v I E HL gtiaksgtae F F 109
Cdd:smart00387 1 GDPDR LR QVL SN LL D N A I K YTPE ---------- G G RIT V T L ER D GDHVEI T VE DNG P G IPPED - L E KI ---------- F E 59
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491457439 110 KNLSG D Q gr D S QL IG QF G V G FYSAFIVADKV tvvsraagtapeqgvqweseg E G SFT V AD vt KE G R GT DVILH L RA E 186
Cdd:smart00387 60 PFFRT D K -- R S RK IG GT G L G LSIVKKLVELH --------------------- G G EIS V ES -- EP G G GT TFTIT L PL E 111
Name
Accession
Description
Interval
E-value
PRK05218
PRK05218 heat shock protein 90; Provisional
6-637
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 1108.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 6 HA ET HG FQ T EVKQLL S LM A HSLYSNKE V FLRELISNASDA A DKLRF K AL S D AS L F E N DG Q L RV R LVV DKE N RTLTISDNG 85
Cdd:PRK05218 2 AM ET GE FQ A EVKQLL H LM I HSLYSNKE I FLRELISNASDA I DKLRF E AL T D PA L Y E G DG D L KI R ISF DKE A RTLTISDNG 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 86 IGMTR DQ VIE H LGTIAKSGT A EF FKN L S GDQ GR DSQLIGQFGVGFYSAF I VADKVTV VS R A AG T A p EQG V Q WES E GEG SF 165
Cdd:PRK05218 82 IGMTR EE VIE N LGTIAKSGT K EF LEK L K GDQ KK DSQLIGQFGVGFYSAF M VADKVTV IT R S AG P A - AEA V R WES D GEG EY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 166 T VADVT KE G RGT DVI LHL RAE E E EFLD D WR L R AVVA KYSD H I S VP VEMF KE gtpdreedgetvvgtpg E W E QV N R A T ALW 245
Cdd:PRK05218 161 T IEEIE KE E RGT EIT LHL KED E D EFLD E WR I R SIIK KYSD F I P VP IKLE KE ----------------- E E E TI N S A S ALW 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 246 TR NPK EI K DEEY Q EFYKH V AHDF E DPL L W G HN R VEG AQ EYT S LLY V P AR APFDL Y NR EQ K H GLKLYV Q RVFIMDDAE QFM 325
Cdd:PRK05218 224 TR SKS EI T DEEY K EFYKH L AHDF D DPL F W I HN N VEG PF EYT G LLY I P KK APFDL F NR DR K G GLKLYV K RVFIMDDAE ELL 303
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 326 P T YLRFVKGV L DS N DLPLNVSREILQ DNK V TVSL RKA CS K R VL TM L A KLAK D D A EKY A KFW S EFG N VLKEG PA ED Y ANRE 405
Cdd:PRK05218 304 P E YLRFVKGV I DS E DLPLNVSREILQ EDR V VKKI RKA IT K K VL DE L E KLAK N D R EKY E KFW K EFG P VLKEG LY ED F ANRE 383
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 406 EI AKLLRFAST AGE gea QT VSL ED YV G RMKEGQ Q KIYYIT A DS FA AAKNSPHLE I F R KKG V EVLL MWERV DE WLM S H L T E 485
Cdd:PRK05218 384 KL AKLLRFAST HEG --- KY VSL AE YV E RMKEGQ K KIYYIT G DS RE AAKNSPHLE L F K KKG I EVLL LTDPI DE FWI S Y L E E 460
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 486 FDGK QLV SV T RG E LDLG D l EDE AS K QAQ EEAE KANAG L V ER V K TS LG EA VK E VR VT HRLTDSP S C I V T D NHG MSTQM I KL 565
Cdd:PRK05218 461 FDGK PFK SV A RG D LDLG K - EDE EE K EEK EEAE EEFKP L L ER L K EA LG DK VK D VR LS HRLTDSP A C L V A D EGD MSTQM E KL 539
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491457439 566 MR AAGQ P VPE Q K Y ILE L NP D H A LVKKL DTIE DEA L F GEWVT LL HE QA Q LAE Q G G L N DPA S FV S R I N R LLL QA 637
Cdd:PRK05218 540 LK AAGQ E VPE S K P ILE I NP N H P LVKKL ADEA DEA K F KDLAE LL YD QA L LAE G G S L E DPA A FV K R L N E LLL KL 611
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
6-637
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 1061.27
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 6 HA ET HG FQ T EVKQLL S LM A HSLYSNKE V FLRELISNASDA A DKLRF K AL S D AS L F E N DG Q L RV R LV VDKE NR TLTISDNG 85
Cdd:COG0326 2 AK ET GE FQ A EVKQLL D LM I HSLYSNKE I FLRELISNASDA I DKLRF L AL T D PE L K E E DG D L KI R IE VDKE AK TLTISDNG 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 86 IGMTR DQ VIE H LGTIAKSGT A EF FKN L S GDQ GR DS Q LIGQFGVGFYSAF I VADKV T VV S R A AG t APEQG V Q WES E G E G SF 165
Cdd:COG0326 82 IGMTR EE VIE N LGTIAKSGT R EF LEK L K GDQ KK DS D LIGQFGVGFYSAF M VADKV E VV T R S AG - EDAEA V R WES D G D G EY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 166 T VADVT K EG RGT DVI LHL RAEE EEFL DD WRLR AVVA KYSD H I S VP VE M FK E GT pdreedgetvvg TPG E W E QV N R ATALW 245
Cdd:COG0326 161 T IEEAE K AE RGT EIT LHL KEDA EEFL EE WRLR EIIK KYSD F I P VP IK M EG E EE ------------ ETE E D E TI N S ATALW 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 246 TR NPK EI K DEEY Q EFYKH VA HDFEDPL L W G H NR VEG AQ EYT S LLY V P AR APFDLY N R EQ K H G L KLYV Q RVFIMDDAE QFM 325
Cdd:COG0326 229 TR SKS EI T DEEY K EFYKH LF HDFEDPL F W I H LN VEG PF EYT G LLY I P KK APFDLY D R DR K G G I KLYV K RVFIMDDAE DLL 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 326 P T YLRFV K GV L DS N DLPLNVSREILQ DNKVTVSL RKA CS K R VL TM L A KLAK D D A EKY A KFW S EFG N VLKEG PA ED YA NRE 405
Cdd:COG0326 309 P E YLRFV R GV V DS P DLPLNVSREILQ EDRQLKKI RKA IT K K VL DE L E KLAK N D R EKY E KFW K EFG L VLKEG AL ED FK NRE 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 406 E IA K LLRF A ST AGE gea QT V S L ED YV G RMKEGQ Q KIYYIT AD S FA AA KN SPHLEIF RK KG V EVLL MWERV DE W L M SHL T E 485
Cdd:COG0326 389 K IA D LLRF E ST KEG --- GY V T L AE YV E RMKEGQ K KIYYIT GE S RE AA EQ SPHLEIF KA KG I EVLL LTDPI DE F L I SHL E E 465
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 486 FDGK QLV SV TR G E LDL GD LE D eas K QAQ EE A E KANAG L V ER V K TS LG EA VK E VRV TH RLTDSP S C I V T D NHG MS TQ M I K L 565
Cdd:COG0326 466 FDGK KFK SV DS G D LDL DK LE E --- K KES EE E E EEFKP L L ER F K EA LG DK VK D VRV SA RLTDSP A C L V A D EGD MS RR M E K M 542
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491457439 566 MR A A GQ PV PE Q K Y ILE L NP D H A LVKKL DTI EDE A LF GEWVT LL HE QA Q LAE Q G G L N DPA S FV S R I N R LL LQ A 637
Cdd:COG0326 543 LK A M GQ DM PE A K P ILE I NP N H P LVKKL AAE EDE E LF KDLAE LL YD QA L LAE G G L L E DPA A FV K R L N K LL EK A 614
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
8-634
0e+00
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 530.02
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 8 ET HG FQ T E VK QL L SL MAHSL YSNKE V FLRELISNASDA A DK L R FKA L S D A S LFENDGQ L RV R L V V DKEN R TLT IS DNGIG 87
Cdd:PTZ00272 3 ET FA FQ A E IN QL M SL IINTF YSNKE I FLRELISNASDA C DK I R YQS L T D P S VLGESPR L CI R V V P DKEN K TLT VE DNGIG 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 88 MT RDQVIEH LGTIA K SGT AE F FKN L sg DQ G R D SQL IGQFGVGFYSA FI VAD K VTV V S R aag TAPEQGVQ WES EGE G S FT V 167
Cdd:PTZ00272 83 MT KADLVNN LGTIA R SGT KA F MEA L -- EA G G D MSM IGQFGVGFYSA YL VAD R VTV T S K --- NNSDESYV WES SAG G T FT I 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 168 ADVTKEG -- RGT DVI LHL RAEEE E F L DDW RL RAVVA K Y S DH I SVPV E MFK E G T PDR E ------------- EDGE ------ 226
Cdd:PTZ00272 158 TSTPESD mk RGT RIT LHL KEDQM E Y L EPR RL KELIK K H S EF I GYDI E LMV E K T TEK E vtdedeedtkkad EDGE epkvee 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 227 ------------- T V VGTPG E W E QV N RATA LWTR N PK EIKD EEY QE FYK HVAH D F EDP LLWG H NR VEG AQ E YT S LLY VP A 293
Cdd:PTZ00272 238 vkegdegkkkktk K V KEVTK E Y E VQ N KHKP LWTR D PK DVTK EEY AA FYK AISN D W EDP AATK H FS VEG QL E FR S IMF VP K 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 294 RAPFD LYNREQ K - HGL KLYV Q RVFIMD DA E QFM P TY L R FVKGV L DS N DLPLN V SRE I LQ D NK VTVSL RK ACS K RV L T M LA 372
Cdd:PTZ00272 318 RAPFD MFEPNK K r NNI KLYV R RVFIMD NC E DLC P DW L G FVKGV V DS E DLPLN I SRE N LQ Q NK ILKVI RK NIV K KC L E M FD 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 373 KL A k DDA E K Y AK F WSE FG NVL K E G PA ED Y ANR EEIAK LLRF A ST A g E GE AQ T v S L E DYV G RMK E GQ QK IYYIT A DS FAAA 452
Cdd:PTZ00272 398 EV A - ENK E D Y KQ F YEQ FG KNI K L G IH ED T ANR KKLME LLRF Y ST E - S GE EM T - T L K DYV T RMK A GQ KS IYYIT G DS KKKL 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 453 KN SP HL E IF R KK G V EVL L M W E RV DE WL M SHLTE F DG K QLVSV T RGELDLGDL E D E as KQ AQ EE AEK A NAG L VERV K TS LG 532
Cdd:PTZ00272 475 ET SP FI E QA R RR G L EVL F M T E PI DE YV M QQVKD F ED K KFACL T KEGVHFEES E E E -- KQ QR EE EKA A CEK L CKTM K EV LG 552
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 533 EA V KE V R V TH RL TD SP SCI VT DNH G M S TQ M IKL MR ------ AAGQPVPEQ K YIL ELNP D H ALV K K L ---- DTI E DEALFG 602
Cdd:PTZ00272 553 DK V EK V I V SE RL ST SP CIL VT SEF G W S AH M EQI MR nqalrd SSMAQYMMS K KTM ELNP R H PII K E L rrrv GAD E NDKAVK 632
650 660 670
....*....|....*....|....*....|..
gi 491457439 603 EW V T LL HEQAQ L AEQGG L N DP ASFVS RINR LL 634
Cdd:PTZ00272 633 DL V F LL FDTSL L TSGFQ L E DP TGYAE RINR MI 664
HSP90
pfam00183 Hsp90 protein;
189-637
1.67e-163
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 478.20
E-value: 1.67e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 189 E F L DDWRLRAV V A KYS DH I SV P VEMFK E GT ----------------------- P DR EE DG E -------- T V VG T PG EWE Q 237
Cdd:pfam00183 1 E Y L EEKKIKEL V K KYS EF I NF P IYLWV E KE eevevpdeeeeeeeeeeeeeddd P KV EE ED E eeekkktk K V KE T VW EWE L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 238 V N RATAL WTRNPKE IKD EEY Q EFYK HVAH D F EDPL LWG H NR VEG AQ E YT SLL YV P A RAPFDL YNREQ K H - GL KLYV Q RVF 316
Cdd:pfam00183 81 L N KTKPI WTRNPKE VTE EEY A EFYK SLSK D W EDPL AVK H FS VEG EV E FK SLL FI P K RAPFDL FENKK K K n NI KLYV R RVF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 317 I M DD A E QFM P T YL R FVKGV L DS N DLPLNVSRE I LQ D NK VTVSLR K ACSKRV L T M LAKL A KDD a E K Y A KFW S EFG NV LK E G 396
Cdd:pfam00183 161 I T DD F E DLI P E YL N FVKGV V DS D DLPLNVSRE T LQ Q NK ILKVIK K KLVRKA L D M FKEI A EEK - E D Y K KFW K EFG KN LK L G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 397 PA ED YA NR EEI AKLLRF A S TAGEG E aq TV SL E DYV G RMKEGQ QK IYYIT AD S FAAAK NSP H LE IFR KKG V EVL LMWERV D 476
Cdd:pfam00183 240 II ED SS NR NKL AKLLRF Y S SKSGD E -- LT SL D DYV S RMKEGQ KH IYYIT GE S KEEVE NSP F LE RLK KKG Y EVL YLTDPI D 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 477 E WLMSH L T EFDGK Q LV S V TRGE L D L GDL E D E as K QAQ EE AE K ANAG L VERV K TS LG EA V KE V R V TH RL T DSP SCI VT DNH 556
Cdd:pfam00183 318 E YAVQQ L K EFDGK K LV N V AKEG L E L EED E E E -- K KKD EE LK K EFEP L TKWL K DV LG DK V EK V V V SN RL V DSP CVL VT SQY 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 557 G M S TQ M IKL M R A - A GQPVP ------ EQ K YI LE L NP D H ALV K K L ---- DTIE D EALFGEWVT LL H E Q A Q L AEQGG L N DPAS 625
Cdd:pfam00183 396 G W S AN M ERI M K A q A LRKDS smssym SS K KT LE I NP R H PII K E L lkrv EADK D DKTAKDLAL LL Y E T A L L RSGFS L E DPAS 475
490
....*....|..
gi 491457439 626 F V SRI N R L L LQA 637
Cdd:pfam00183 476 F A SRI Y R M L KLG 487
PTZ00130
PTZ00130 heat shock protein 90; Provisional
8-624
6.45e-137
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain]
Cd Length: 814
Bit Score: 419.83
E-value: 6.45e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 8 E T H GF QTEV KQ L LSLMAH SLY SN KEVFLRELISNA S DA AD K L RF KA LSD A S LFENDGQ L RV R LVVD KE NRT L T I S D N GIG 87
Cdd:PTZ00130 66 E Q H QY QTEV TR L MDIIVN SLY TQ KEVFLRELISNA A DA LE K I RF LS LSD E S VLGEEKK L EI R ISAN KE KNI L S I T D T GIG 145
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 88 MT RDQV I EH LGTIAKSGT AE F FKNL S g DQ G R D SQ LIGQFGVGFYSAF I VADKV T V VSR aa GTAP EQ GV q WES EGEGS FT V 167
Cdd:PTZ00130 146 MT KEDL I NN LGTIAKSGT SN F LEAI S - KS G G D MS LIGQFGVGFYSAF L VADKV I V YTK -- NNND EQ YI - WES TADAK FT I 221
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 168 ADVTKEG --- RGT DVI LHL RAEEEEFLD D WR L RAVVA KYS DH I SV P VEMFK E G --------------------------- 217
Cdd:PTZ00130 222 YKDPRGS tlk RGT RIS LHL KEDATNLMN D KK L VDLIS KYS QF I QY P IYLLH E N vyteevladiakemendpnydsvkvee 301
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 218 T P D REEDGE TV VGTPGE W EQV N RATAL W T R N PKE IK DE E Y QE F YKHVAHDFED PL LWG H NRV EG AQ E YTS L L Y V P A RAP F 297
Cdd:PTZ00130 302 T D D PNKKTR TV EKKVKK W KLM N EQKPI W L R P PKE LT DE D Y KK F FSVLSGFNDE PL YHI H FFA EG EI E FKC L I Y I P S RAP S 381
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 298 --- D L YNRE qk HGL KLYV Q RV FIM D DAEQ F M P T Y LR FVKGV L DS N DLPLNVSRE I LQ D NK VTVSLR K ACSKRV L ------ 368
Cdd:PTZ00130 382 ind H L FTKQ -- NSI KLYV R RV LVA D EFVE F L P R Y MS FVKGV V DS D DLPLNVSRE Q LQ Q NK ILKAVS K RIVRKI L dtfrtl 459
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 369 --------- T ML A K LAK D - D A EK ------------- Y AKFWS E FGNV LK E G PA ED YA NR EE I A KLL R F ASTA geg EAQTV 425
Cdd:PTZ00130 460 ykegkknke T LR A E LAK E t D E EK kkeiqkkinepst Y KLIYK E YRKY LK T G CY ED DI NR NK I V KLL L F KTML --- HPKSI 536
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 426 SL ED Y VGR MK EG Q QK IYY ITA DS FAAAKNS P H L E IF R KK GVE V LLMW E R VDE WLMSHLT E F DGK QLV S VTR GE LDLGDL E 505
Cdd:PTZ00130 537 SL DT Y IEN MK PD Q KF IYY ASG DS YEYLSKI P Q L Q IF K KK NID V VFLT E S VDE SCVQRVQ E Y DGK KFK S IQK GE ITFELT E 616
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 506 DE as K QAQ E EAE K ANAG L VERVKTS L GEAVKE V RVTH RL T D S P SCI V TDNH G M S T QM I KLM RAAGQPVPEQ K Y ----- IL 580
Cdd:PTZ00130 617 DE -- K KKE E KVK K MYKA L IDVISDT L RNQIFK V EISR RL V D A P CAV V STEW G L S G QM E KLM KINVNNSDQI K A msgqk IL 694
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 491457439 581 E L NPDH A ---- L V K KLDTIEDEALFG E WVTLLHEQ A Q LA EQGG L N D P A 624
Cdd:PTZ00130 695 E I NPDH P imid L L K RSVSNPKDSQLT E SIKIIYQS A K LA SGFD L E D T A 742
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
17-207
4.59e-103
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 310.61
E-value: 4.59e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 17 K QLL S L MA HSLYSNKE V FLRELISNASDA A DKLR FKA L S D A SL FEN D GQ L RV R LVV DKENRTLTISD N GIGMT RDQV I EH 96
Cdd:cd16927 1 N QLL D L II HSLYSNKE I FLRELISNASDA L DKLR YLS L T D P SL LDD D PE L EI R ISP DKENRTLTISD T GIGMT KEEL I NN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 97 LGTIA K SGT AE F FKN L SGDQG r DS Q LIGQFGVGFYSAF I VADKVTV VSRA AG ta PEQ G VQ WES E G E GS F T VADVTK E - GR 175
Cdd:cd16927 81 LGTIA R SGT KA F LEA L QEGAK - DS D LIGQFGVGFYSAF M VADKVTV TTKS AG -- DDE G YR WES D G G GS Y T IEEAEG E l GR 157
170 180 190
....*....|....*....|....*....|..
gi 491457439 176 GT DVI LHL RAEEE EFL DDW R LRAV V A KYSD H I 207
Cdd:cd16927 158 GT KIT LHL KEDAK EFL EEA R IKEL V K KYSD F I 189
PRK14083
PRK14083 HSP90 family protein; Provisional
10-614
1.12e-45
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain]
Cd Length: 601
Bit Score: 171.28
E-value: 1.12e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 10 H G FQ TEVKQLLS L MAHS LYS NKE V FL REL IS NA S DA ADKL R f KALSD A S lfend G QL R VR L V v D KENR TL TIS DNGIG M T 89
Cdd:PRK14083 3 H R FQ VDLRGVID L LSRH LYS SPR V YV REL LQ NA V DA ITAR R - ALDPT A P ----- G RI R IE L T - D AGGG TL IVE DNGIG L T 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 90 RDQ V I E H L G TI AK S GT - A E FF knlsg DQG R D s QLI GQFG V G FY S A F I VAD KVT VVSR A A GTA P eq G V Q W ESEGE G SFT V A 168
Cdd:PRK14083 76 EEE V H E F L A TI GR S SK r D E NL ----- GFA R N - DFL GQFG I G LL S C F L VAD EIV VVSR S A KDG P -- A V E W RGKAD G TYS V R 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 169 DVTK E GR -- GT D V I L HL R AEE EE F L DDWRLRAVVA KY SDHIS VP V emfkegtpdreedget V V G tp GE WEQ VN RATAL WT 246
Cdd:PRK14083 148 KLET E RA ep GT T V Y L RP R PDA EE W L ERETVEELAK KY GSLLP VP I ---------------- R V E -- GE KGG VN ETPPP WT 209
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 247 R NP -- K E IKD E EYQEFYKHV - AHDFE D -- PL LWGHNRV EG aqeyts LL YV - P ARAPF dly NREQ KH gl KL Y VQ R VFIMDD 320
Cdd:PRK14083 210 R DY pd P E TRR E ALLAYGEEL l GFTPL D vi PL DVPSGGL EG ------ VA YV l P YAVSP --- AARR KH -- RV Y LK R MLLSEE 278
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 321 AE QFM P TYLR FV KG V LDSND L PLNV SRE I L QDNKVTVSL R KACSKRVLTM L AK LA KD D A E KYAKFWSEFGNVL K EGPAE D 400
Cdd:PRK14083 279 AE NLL P DWAF FV RC V VNTDE L RPTA SRE A L YEDDALAAV R EELGEAIRKW L IG LA TT D P E RLRRLLAVHHLGV K ALASH D 358
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 401 YANREE I AKL L R F AS T A G egeaq TVS L EDY vgr MKEGQQ k I Y Y I - TA D S F A -- A A knsphle I F R KK G VE V LLMWERV D E 477
Cdd:PRK14083 359 DELLRL I LPW L P F ET T D G ----- RMT L AEI --- RRRHGV - I R Y T s SV D E F R ql A P ------- I A R AQ G MG V INGGYTY D S 422
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 478 W L MSH L TEFDGKQL V S vtrg E LD LGD L E D EASKQAQ EE AEKA n AGLVERVKTS L GEAVKE V RVT H RLTDS - P SCIVT D NH 556
Cdd:PRK14083 423 E L LER L PRLRPGLT V E ---- R LD PAE L T D RLEPLTP EE ELAL - RPFLAEAREV L APFGCD V VIR H FEPAD l P ALYLH D RA 497
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491457439 557 GMSTQMIK ---------------- L MRAAGQ P VPE qkyi L E LN PDHA LV KK L D T IE D EA L FGEW V TL L HE QA Q L 614
Cdd:PRK14083 498 AQHSRERE eaveeaddlwadilgs L DESQPA P RAR ---- L V LN LRNP LV RR L A T LG D PK L LSRA V EA L YV QA L L 567
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
30-186
1.05e-11
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 61.90
E-value: 1.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 30 NKEVF LR ELI SN AS D A A D K LRFK alsdaslfen D G QLR V R L VV D KENRTL T IS DNG I G MTRDQ v I E HL gtiaksgtae F F 109
Cdd:smart00387 1 GDPDR LR QVL SN LL D N A I K YTPE ---------- G G RIT V T L ER D GDHVEI T VE DNG P G IPPED - L E KI ---------- F E 59
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491457439 110 KNLSG D Q gr D S QL IG QF G V G FYSAFIVADKV tvvsraagtapeqgvqweseg E G SFT V AD vt KE G R GT DVILH L RA E 186
Cdd:smart00387 60 PFFRT D K -- R S RK IG GT G L G LSIVKKLVELH --------------------- G G EIS V ES -- EP G G GT TFTIT L PL E 111
HATPase_c
pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ...
30-187
6.23e-07
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain]
Cd Length: 109
Bit Score: 48.13
E-value: 6.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 30 NK E VF LR ELI SN AS D A A D K LRF KA lsdaslfend G QLR V R L VVDK E NR t LT IS DNGIG MTRDQ v IEHLGT iaksgta E F F 109
Cdd:pfam02518 1 GD E LR LR QVL SN LL D N A L K HAA KA ---------- G EIT V T L SEGG E LT - LT VE DNGIG IPPED - LPRIFE ------- P F S 61
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491457439 110 KNLSGDQ G R dsqligq F G V G FYSAFIVADKV tvvsraagtapeqgvqweseg E G SF TV A dv TKE G R GT D V I L H L RAEE 187
Cdd:pfam02518 62 TADKRGG G G ------- T G L G LSIVRKLVELL --------------------- G G TI TV E -- SEP G G GT T V T L T L PLAQ 109
HATPase_TopVIB-like
cd16933 Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ...
36-207
5.58e-05
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain]
Cd Length: 203
Bit Score: 44.65
E-value: 5.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 36 REL IS N AS DA AD klrfkals D A SLFEN dgq LR V RL - VVD K ENRTLTIS DNG I G MTRD Q viehlgt I A K S gtae F F K N L S G 114
Cdd:cd16933 25 REL VE N SL DA TE -------- E A GILPD --- IK V EI e EIG K DHYKVIVE DNG P G IPEE Q ------- I P K V ---- F G K V L Y G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 115 DQGRDS Q LI GQ F G V G ----- F YS AFIVADK V TVV S RAAGTAPEQG V QW ----- ES E G E gsf TVADVTK E G R ---- GT D V I 180
Cdd:cd16933 83 SKYHNK Q SR GQ Q G L G isaav L YS QMTTGKP V EII S STKDSNYAYV V KL midtd KN E P E --- ILEKEEV E N R ykwh GT R V E 159
170 180 190
....*....|....*....|....*....|.
gi 491457439 181 L H L RAE --- EEEFLDDWRL R - AV V A K Y SDH I 207
Cdd:cd16933 160 L E L EGN wva ARSQILEYYK R t AV I A P Y AEI I 190
HATPase_c_3
pfam13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ...
32-149
4.40e-04
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain]
Cd Length: 135
Bit Score: 40.78
E-value: 4.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491457439 32 E VF L R ELI S N AS DA adklrfkals DA slfendgq LRVRLV V D K E --- NRTLT I S D N G I GM TRDQV I EH L G t I A K S GT aef 108
Cdd:pfam13589 2 E GA L A ELI D N SI DA ---------- DA -------- TNIKIE V N K N rgg GTEIV I E D D G H GM SPEEL I NA L R - L A T S AK --- 59
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 491457439 109 fknlsg DQG R D S QLI G QF G V G FYS A - FIVAD K V TV V S RAA G T 149
Cdd:pfam13589 60 ------ EAK R G S TDL G RY G I G LKL A s LSLGA K L TV T S KKE G K 95
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
