|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00180 |
PRK00180 |
acetate kinase A/propionate kinase 2; Reviewed |
3-400 |
0e+00 |
|
acetate kinase A/propionate kinase 2; Reviewed
Pssm-ID: 234680 Cd Length: 402 Bit Score: 707.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 3 KLVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADLGAGAAHQEALDFIVNKILPLNPELSK 82
Cdd:PRK00180 1 MKILVLNAGSSSLKFQLIDMPNEEVLASGLVERIGLPDSRIKIKVDGGEKEEEELPIPDHAEALKFLLNTLTDGKLGLIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 83 NL---IAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEE 159
Cdd:PRK00180 81 DLdeiTAVGHRVVHGGEKFTESVLIDDEVLAAIEELSPLAPLHNPANLIGIEAARKLLPNV--PQVAVFDTAFHQTMPEE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 160 AFLYALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVM 239
Cdd:PRK00180 159 AYLYALPYELYEKYGIRRYGFHGTSHRYVSQRAAELLGKPLEELNLITCHLGNGASIAAIKNGKSVDTSMGFTPLEGLVM 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 240 GTRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYDSKEE-AKRAMDVYCYRLAKYIGAYAA 318
Cdd:PRK00180 239 GTRSGDIDPAIIPYLMEKLGMSVDEIDNLLNKKSGLLGLSGVSSDMRDIEAAAEEGDErAKLALDVFVYRLAKYIGSYAA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 319 AMDGRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLKARFGKGGEITKAGST-KALVIPTNEEWVIAHDALEL 397
Cdd:PRK00180 319 ALNGRLDAIVFTAGIGENSALVREKVLEGLEFLGIELDPEKNLAARFGKEGDISTPDSKvKVLVIPTNEELMIARDTLRL 398
|
...
gi 491491476 398 VGA 400
Cdd:PRK00180 399 LGK 401
|
|
| AckA |
COG0282 |
Acetate kinase [Energy production and conversion]; |
3-399 |
0e+00 |
|
Acetate kinase [Energy production and conversion];
Pssm-ID: 440051 Cd Length: 395 Bit Score: 648.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 3 KLVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKL-NGEKGSADLgAGAAHQEALDFIVNKILPLNPELS 81
Cdd:COG0282 1 MKILVLNAGSSSLKFQLFDMDSEEVLAKGLVERIGLPGARLKHKDaGGEKVEREL-PIPDHAAALALVLELLTDHGIIKD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 82 KN-LIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEEA 160
Cdd:COG0282 80 LDeIDAVGHRVVHGGEKFSESVLIDDEVLAAIEELIPLAPLHNPANLAGIEAARELLPDL--PQVAVFDTAFHQTMPEVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 161 FLYALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVMG 240
Cdd:COG0282 158 YLYALPYELYEKYGIRRYGFHGTSHRYVAERAAELLGKPLADLRLITAHLGNGASLCAIKNGKSVDTSMGFTPLEGLVMG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 241 TRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYDS-KEEAKRAMDVYCYRLAKYIGAYAAA 319
Cdd:COG0282 238 TRSGDIDPGVVLYLMRKEGLSADEVDDLLNKESGLLGLSGISSDMRDLEEAAASgDERARLALDMFVYRIKKYIGAYAAA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 320 MdGRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANlkARFGKGGEITKAGS-TKALVIPTNEEWVIAHDALELV 398
Cdd:COG0282 318 L-GGLDALVFTAGIGENSAEVRARVCEGLEFLGIELDPEAN--AARGGERVISTPDSrVKVLVIPTNEELMIARDTLRLL 394
|
.
gi 491491476 399 G 399
Cdd:COG0282 395 K 395
|
|
| ASKHA_NBD_AcK_PK |
cd24010 |
nucleotide-binding domain (NBD) of the acetate kinase (AcK)/propionate kinase (PK) domain ... |
5-397 |
0e+00 |
|
nucleotide-binding domain (NBD) of the acetate kinase (AcK)/propionate kinase (PK) domain family; The family corresponds to a group of proteins which transfer phosphate from ATP to a short chain aliphatic acid. It includes acetate kinase (AckA) and propionate kinase (TdcD and PduW). Acetate kinase (EC 2.7.2.1), also called acetokinase, catalyzes the formation of acetyl phosphate from acetate and ATP. It can also catalyze the reverse reaction in the presence of a divalent cation. During anaerobic growth of the organism, this enzyme is also involved in the synthesis of most of the ATP formed catabolically. Propionate kinase TdcD (EC 2.7.2.15) catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. It can also use acetyl phosphate as phosphate group acceptor. The family also includes propionate kinase PduW (EC 2.7.2.15) that works with phosphate acetyltransferase (pta) to capture exogenous propionate and regenerate propionyl-CoA during degradation of propionate and 1,2-propanediol (1,2-PD). This protein restores growth to an eutQ deletion on ethanolamine and tetrathionate under anoxic conditions. The AcK/PK family belongs to the ASKHA (Acetate and Sugar Kinases/Hsc70/Actin) superfamily of phosphotransferases, all members of which share a common characteristic five-stranded beta sheet occurring in both the N- and C-terminal domains.
Pssm-ID: 466860 Cd Length: 392 Bit Score: 614.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 5 VLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADLGAGAAHQEALDFIVNKILPLNPELSKNL 84
Cdd:cd24010 1 ILVINCGSSSLKFQLFDMPTEEVLASGLVERIGLEGARLKHKVNNGEKIKEELPIPDHEEALKAILDTLTDPELGVSLDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 85 I-AIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEEAFLY 163
Cdd:cd24010 81 IdAVGHRVVHGGEKFTESVLIDDEVIAAIEDLSPLAPLHNPANLAGIEAARKLLPDV--PQVAVFDTAFHQTMPPHAYLY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 164 ALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVMGTRS 243
Cdd:cd24010 159 ALPYELYEKYGIRRYGFHGTSHRYVSRRAAELLGKPLEDLNLITCHLGNGASICAIKNGKSVDTSMGLTPLEGLVMGTRS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 244 GDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYDSKEE-AKRAMDVYCYRLAKYIGAYAAAMdG 322
Cdd:cd24010 239 GDIDPAIVFYLMKKEGMSVDEIERLLNKKSGLLGISGVSSDMRDIEEAAEEGDErAKLALDVFVYRIKKYIGAYAAAL-G 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491491476 323 RLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANlKARFGKGGEITKAGS-TKALVIPTNEEWVIAHDALEL 397
Cdd:cd24010 318 GVDAIVFTGGIGENSALIRELVCEGLEFLGIELDEEKN-KAAGGGEREISTPDSkVKVLVIPTNEELMIARDTVRL 392
|
|
| ackA |
TIGR00016 |
acetate kinase; Acetate kinase is involved in the activation of acetate to acetyl CoA and in ... |
1-397 |
0e+00 |
|
acetate kinase; Acetate kinase is involved in the activation of acetate to acetyl CoA and in the secretion of acetate. It catalyzes the reaction ATP + acetate = ADP + acetyl phosphate. Some members of this family have been shown to act on propionate as well as acetate. An example of a propionate/acetate kinase is TdcD of E. coli (SP|P11868), an enzyme of an anaerobic pathway of threonine catabolism. It is not known how many members of this family act on additional substrates besides acetate. [Energy metabolism, Fermentation]
Pssm-ID: 272856 Cd Length: 404 Bit Score: 604.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 1 MSKLVLVLNCGSSSLKFAVIDATTGDD-LLSGLAECFNLDDARIKWKLNGEKGSADLGAGAAHQEALDFIVNKILPLN-P 78
Cdd:TIGR00016 2 SSMKILVLNAGSSSLKFALFDAVNGEEvLASGLAERIFLPNARIKWVEDGGKKEAELLAGADHQEALKFILNTLLKDKiI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 79 ELSKNLIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALADKNVAVFDTAFHQTMPE 158
Cdd:TIGR00016 82 KLLSEIDLIGHRVVHGGEKFTDSVIITDEVIQKIKDISPLAPLHNPAHLIGIEAALKLFPLPKAKNVAVFDTAFHQTMPE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 159 EAFLYALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLV 238
Cdd:TIGR00016 162 EAYLYALPYSWYKEHGVRRYGFHGTSHKYVTQRAAKILNKPLDDLNLIVCHLGNGASVCAIKNGKSIDTSMGFTPLEGLM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 239 MGTRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYD-SKEEAKRAMDVYCYRLAKYIGAYA 317
Cdd:TIGR00016 242 MGTRSGDIDPAIIFYLAETLGMSADDIENTLNKKSGLLGISGLSSDLRDIEDAYAeGNEQAKLAIKVYVHRIAKYIGSYI 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 318 AAMDGRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLKARFGKGGEITKAGST-KALVIPTNEEWVIAHDALE 396
Cdd:TIGR00016 322 ASLEGNLDAIVFTGGIGENAAMVRELVLEKLEVLGFELDPELNNAARSGKSGVISTPESKvKILVIPTNEELMIAQDAIR 401
|
.
gi 491491476 397 L 397
Cdd:TIGR00016 402 L 402
|
|
| Acetate_kinase |
pfam00871 |
Acetokinase family; This family includes acetate kinase, butyrate kinase and ... |
4-391 |
0e+00 |
|
Acetokinase family; This family includes acetate kinase, butyrate kinase and 2-methylpropanoate kinase.
Pssm-ID: 395700 Cd Length: 387 Bit Score: 589.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 4 LVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADLGAGAAHQEALDFIVNKILPLN-PELSK 82
Cdd:pfam00871 1 KVLVLNAGSSSIKFQLFDAVIGEVLLSGLAERIGLPNARILWKMNGGKKNAALLAGADHSEALNFILNTLLKHKiIELLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 83 NLIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEEAFL 162
Cdd:pfam00871 81 EITLIGHRVVHGGEKFTESVLITDEVIQGIKDLIPLAPLHNPAHLDGIEEAFKLFPQV--KNVAVFDTAFHQTMPEEAYL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 163 YALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVMGTR 242
Cdd:pfam00871 159 YALPYSWYKEHGIRRYGFHGTSHKYVSQRAAKILNKPLEDLNLITCHLGNGASVCAVRNGKSVDTSMGFTPLEGLVMGTR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 243 SGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYD-SKEEAKRAMDVYCYRLAKYIGAYAAAMd 321
Cdd:pfam00871 239 SGDIDPAIIFYLAETLGMSADEINNTLNKKSGLLGLSGVSSDLRYVEDAYAeGKEDAQLAIKVYVHRLAKYIGSYAASL- 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491491476 322 GRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLkaRFGKGGEITKAGS-TKALVIPTNEEWVIA 391
Cdd:pfam00871 318 ERLDAIVFTGGIGENAAMVRELVLNALEVLGFEIDPERNN--RFGKSGVISTEDSrVKVVVIPTNEELMIA 386
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00180 |
PRK00180 |
acetate kinase A/propionate kinase 2; Reviewed |
3-400 |
0e+00 |
|
acetate kinase A/propionate kinase 2; Reviewed
Pssm-ID: 234680 Cd Length: 402 Bit Score: 707.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 3 KLVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADLGAGAAHQEALDFIVNKILPLNPELSK 82
Cdd:PRK00180 1 MKILVLNAGSSSLKFQLIDMPNEEVLASGLVERIGLPDSRIKIKVDGGEKEEEELPIPDHAEALKFLLNTLTDGKLGLIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 83 NL---IAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEE 159
Cdd:PRK00180 81 DLdeiTAVGHRVVHGGEKFTESVLIDDEVLAAIEELSPLAPLHNPANLIGIEAARKLLPNV--PQVAVFDTAFHQTMPEE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 160 AFLYALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVM 239
Cdd:PRK00180 159 AYLYALPYELYEKYGIRRYGFHGTSHRYVSQRAAELLGKPLEELNLITCHLGNGASIAAIKNGKSVDTSMGFTPLEGLVM 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 240 GTRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYDSKEE-AKRAMDVYCYRLAKYIGAYAA 318
Cdd:PRK00180 239 GTRSGDIDPAIIPYLMEKLGMSVDEIDNLLNKKSGLLGLSGVSSDMRDIEAAAEEGDErAKLALDVFVYRLAKYIGSYAA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 319 AMDGRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLKARFGKGGEITKAGST-KALVIPTNEEWVIAHDALEL 397
Cdd:PRK00180 319 ALNGRLDAIVFTAGIGENSALVREKVLEGLEFLGIELDPEKNLAARFGKEGDISTPDSKvKVLVIPTNEELMIARDTLRL 398
|
...
gi 491491476 398 VGA 400
Cdd:PRK00180 399 LGK 401
|
|
| AckA |
COG0282 |
Acetate kinase [Energy production and conversion]; |
3-399 |
0e+00 |
|
Acetate kinase [Energy production and conversion];
Pssm-ID: 440051 Cd Length: 395 Bit Score: 648.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 3 KLVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKL-NGEKGSADLgAGAAHQEALDFIVNKILPLNPELS 81
Cdd:COG0282 1 MKILVLNAGSSSLKFQLFDMDSEEVLAKGLVERIGLPGARLKHKDaGGEKVEREL-PIPDHAAALALVLELLTDHGIIKD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 82 KN-LIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEEA 160
Cdd:COG0282 80 LDeIDAVGHRVVHGGEKFSESVLIDDEVLAAIEELIPLAPLHNPANLAGIEAARELLPDL--PQVAVFDTAFHQTMPEVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 161 FLYALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVMG 240
Cdd:COG0282 158 YLYALPYELYEKYGIRRYGFHGTSHRYVAERAAELLGKPLADLRLITAHLGNGASLCAIKNGKSVDTSMGFTPLEGLVMG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 241 TRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYDS-KEEAKRAMDVYCYRLAKYIGAYAAA 319
Cdd:COG0282 238 TRSGDIDPGVVLYLMRKEGLSADEVDDLLNKESGLLGLSGISSDMRDLEEAAASgDERARLALDMFVYRIKKYIGAYAAA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 320 MdGRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANlkARFGKGGEITKAGS-TKALVIPTNEEWVIAHDALELV 398
Cdd:COG0282 318 L-GGLDALVFTAGIGENSAEVRARVCEGLEFLGIELDPEAN--AARGGERVISTPDSrVKVLVIPTNEELMIARDTLRLL 394
|
.
gi 491491476 399 G 399
Cdd:COG0282 395 K 395
|
|
| ASKHA_NBD_AcK_PK |
cd24010 |
nucleotide-binding domain (NBD) of the acetate kinase (AcK)/propionate kinase (PK) domain ... |
5-397 |
0e+00 |
|
nucleotide-binding domain (NBD) of the acetate kinase (AcK)/propionate kinase (PK) domain family; The family corresponds to a group of proteins which transfer phosphate from ATP to a short chain aliphatic acid. It includes acetate kinase (AckA) and propionate kinase (TdcD and PduW). Acetate kinase (EC 2.7.2.1), also called acetokinase, catalyzes the formation of acetyl phosphate from acetate and ATP. It can also catalyze the reverse reaction in the presence of a divalent cation. During anaerobic growth of the organism, this enzyme is also involved in the synthesis of most of the ATP formed catabolically. Propionate kinase TdcD (EC 2.7.2.15) catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. It can also use acetyl phosphate as phosphate group acceptor. The family also includes propionate kinase PduW (EC 2.7.2.15) that works with phosphate acetyltransferase (pta) to capture exogenous propionate and regenerate propionyl-CoA during degradation of propionate and 1,2-propanediol (1,2-PD). This protein restores growth to an eutQ deletion on ethanolamine and tetrathionate under anoxic conditions. The AcK/PK family belongs to the ASKHA (Acetate and Sugar Kinases/Hsc70/Actin) superfamily of phosphotransferases, all members of which share a common characteristic five-stranded beta sheet occurring in both the N- and C-terminal domains.
Pssm-ID: 466860 Cd Length: 392 Bit Score: 614.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 5 VLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADLGAGAAHQEALDFIVNKILPLNPELSKNL 84
Cdd:cd24010 1 ILVINCGSSSLKFQLFDMPTEEVLASGLVERIGLEGARLKHKVNNGEKIKEELPIPDHEEALKAILDTLTDPELGVSLDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 85 I-AIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEEAFLY 163
Cdd:cd24010 81 IdAVGHRVVHGGEKFTESVLIDDEVIAAIEDLSPLAPLHNPANLAGIEAARKLLPDV--PQVAVFDTAFHQTMPPHAYLY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 164 ALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVMGTRS 243
Cdd:cd24010 159 ALPYELYEKYGIRRYGFHGTSHRYVSRRAAELLGKPLEDLNLITCHLGNGASICAIKNGKSVDTSMGLTPLEGLVMGTRS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 244 GDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYDSKEE-AKRAMDVYCYRLAKYIGAYAAAMdG 322
Cdd:cd24010 239 GDIDPAIVFYLMKKEGMSVDEIERLLNKKSGLLGISGVSSDMRDIEEAAEEGDErAKLALDVFVYRIKKYIGAYAAAL-G 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491491476 323 RLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANlKARFGKGGEITKAGS-TKALVIPTNEEWVIAHDALEL 397
Cdd:cd24010 318 GVDAIVFTGGIGENSALIRELVCEGLEFLGIELDEEKN-KAAGGGEREISTPDSkVKVLVIPTNEELMIARDTVRL 392
|
|
| ackA |
TIGR00016 |
acetate kinase; Acetate kinase is involved in the activation of acetate to acetyl CoA and in ... |
1-397 |
0e+00 |
|
acetate kinase; Acetate kinase is involved in the activation of acetate to acetyl CoA and in the secretion of acetate. It catalyzes the reaction ATP + acetate = ADP + acetyl phosphate. Some members of this family have been shown to act on propionate as well as acetate. An example of a propionate/acetate kinase is TdcD of E. coli (SP|P11868), an enzyme of an anaerobic pathway of threonine catabolism. It is not known how many members of this family act on additional substrates besides acetate. [Energy metabolism, Fermentation]
Pssm-ID: 272856 Cd Length: 404 Bit Score: 604.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 1 MSKLVLVLNCGSSSLKFAVIDATTGDD-LLSGLAECFNLDDARIKWKLNGEKGSADLGAGAAHQEALDFIVNKILPLN-P 78
Cdd:TIGR00016 2 SSMKILVLNAGSSSLKFALFDAVNGEEvLASGLAERIFLPNARIKWVEDGGKKEAELLAGADHQEALKFILNTLLKDKiI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 79 ELSKNLIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALADKNVAVFDTAFHQTMPE 158
Cdd:TIGR00016 82 KLLSEIDLIGHRVVHGGEKFTDSVIITDEVIQKIKDISPLAPLHNPAHLIGIEAALKLFPLPKAKNVAVFDTAFHQTMPE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 159 EAFLYALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLV 238
Cdd:TIGR00016 162 EAYLYALPYSWYKEHGVRRYGFHGTSHKYVTQRAAKILNKPLDDLNLIVCHLGNGASVCAIKNGKSIDTSMGFTPLEGLM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 239 MGTRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYD-SKEEAKRAMDVYCYRLAKYIGAYA 317
Cdd:TIGR00016 242 MGTRSGDIDPAIIFYLAETLGMSADDIENTLNKKSGLLGISGLSSDLRDIEDAYAeGNEQAKLAIKVYVHRIAKYIGSYI 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 318 AAMDGRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLKARFGKGGEITKAGST-KALVIPTNEEWVIAHDALE 396
Cdd:TIGR00016 322 ASLEGNLDAIVFTGGIGENAAMVRELVLEKLEVLGFELDPELNNAARSGKSGVISTPESKvKILVIPTNEELMIAQDAIR 401
|
.
gi 491491476 397 L 397
Cdd:TIGR00016 402 L 402
|
|
| Acetate_kinase |
pfam00871 |
Acetokinase family; This family includes acetate kinase, butyrate kinase and ... |
4-391 |
0e+00 |
|
Acetokinase family; This family includes acetate kinase, butyrate kinase and 2-methylpropanoate kinase.
Pssm-ID: 395700 Cd Length: 387 Bit Score: 589.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 4 LVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADLGAGAAHQEALDFIVNKILPLN-PELSK 82
Cdd:pfam00871 1 KVLVLNAGSSSIKFQLFDAVIGEVLLSGLAERIGLPNARILWKMNGGKKNAALLAGADHSEALNFILNTLLKHKiIELLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 83 NLIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEEAFL 162
Cdd:pfam00871 81 EITLIGHRVVHGGEKFTESVLITDEVIQGIKDLIPLAPLHNPAHLDGIEEAFKLFPQV--KNVAVFDTAFHQTMPEEAYL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 163 YALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVMGTR 242
Cdd:pfam00871 159 YALPYSWYKEHGIRRYGFHGTSHKYVSQRAAKILNKPLEDLNLITCHLGNGASVCAVRNGKSVDTSMGFTPLEGLVMGTR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 243 SGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYD-SKEEAKRAMDVYCYRLAKYIGAYAAAMd 321
Cdd:pfam00871 239 SGDIDPAIIFYLAETLGMSADEINNTLNKKSGLLGLSGVSSDLRYVEDAYAeGKEDAQLAIKVYVHRLAKYIGSYAASL- 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491491476 322 GRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLkaRFGKGGEITKAGS-TKALVIPTNEEWVIA 391
Cdd:pfam00871 318 ERLDAIVFTGGIGENAAMVRELVLNALEVLGFEIDPERNN--RFGKSGVISTEDSrVKVVVIPTNEELMIA 386
|
|
| PRK12440 |
PRK12440 |
acetate/propionate family kinase; |
4-398 |
5.05e-164 |
|
acetate/propionate family kinase;
Pssm-ID: 183528 Cd Length: 397 Bit Score: 465.87 E-value: 5.05e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 4 LVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADL-GAGAAHQEALDFIVNKILPLNpeLSK 82
Cdd:PRK12440 5 YVLVINSGSSSLKFAVIDSVTGEAVLSGLGECFGLEDARMSWKYQGEKTEIAIeGEDNHHKIAIGRLVGLTEELG--FTQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 83 NLIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALAdkNVAVFDTAFHQTMPEEAFL 162
Cdd:PRK12440 83 DIVAVGHRIVHGGEKFTSTVRIDEEVTAEIESLSDLAPLHNPAGAIGIRAAMAAFPSLP--QFAVFDTAFHQTMPKKAFT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 163 YALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVMGTR 242
Cdd:PRK12440 161 GAIAKELYTDFGIRRYGFHGTSHYFVSREAAKMLNKPIEESSFISVHLGNGASVCAIKNGQSVDTSMGFTPLSGLMMGTR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 243 SGDLDPAIIFFLHDKlGMSVADINTMLTKESGLQGLTEVTSDCR-FVEDNYDSKEEAKRAMDVYCYRLAKYIGAYAAAMD 321
Cdd:PRK12440 241 CGDLDPGIIEFLLKK-GWSQEKVFNSLNKKSGFLGVSGLTSDARgILEAMEEGHEGATLAFEVFTYRVAKYIASYLAALD 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491491476 322 gRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLKARFGKGGEITKAG--STKALVIPTNEEWVIAHDALELV 398
Cdd:PRK12440 320 -SLDGIIFTGGIGENSLPIRREILKNLKLLGFVEDEKGNEDARFGKAGIIAKSEllNAVAMVIPTNEEFVIAQQSVELL 397
|
|
| PRK12379 |
PRK12379 |
propionate kinase; |
4-397 |
1.92e-148 |
|
propionate kinase;
Pssm-ID: 183484 Cd Length: 396 Bit Score: 426.07 E-value: 1.92e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 4 LVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKwkLNGekGSADLGAGAAHQEALDFIVNKILPLNpeLSKN 83
Cdd:PRK12379 6 VVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLS--VNG--GEPAPLAHHSYEGALKAIAFELEKRN--LNDS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 84 LIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEEAFLY 163
Cdd:PRK12379 80 VALIGHRIAHGGSIFTESVIITDEVIDNIRRVSPLAPLHNYANLSGIEAAQQLFPGV--TQVAVFDTSFHQTLAPEAYLY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 164 ALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVMGTRS 243
Cdd:PRK12379 158 GLPWEYYEELGVRRYGFHGTSHRYVSQRAHSLLNLDEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 244 GDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNY-DSKEEAKRAMDVYCYRLAKYIGAYAAAMDg 322
Cdd:PRK12379 238 GDVDFGAMAWIASQTGQTLGDLERVVNKESGLLGISGLSSDLRVLEKAWhEGHERAQLAIKTFVHRIARHIAGHAASLH- 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491491476 323 RLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANlkARFGKGGE--ITKAGSTK-ALVIPTNEEWVIAHDALEL 397
Cdd:PRK12379 317 RLDGIIFTGGIGENSSLIRRLVMEHLAVLGLEIDTEMN--NQPNSGGEriISSENSRViCAVIPTNEEKMIALDAIHL 392
|
|
| PRK12397 |
PRK12397 |
acetate/propionate family kinase; |
1-397 |
5.45e-125 |
|
acetate/propionate family kinase;
Pssm-ID: 183500 Cd Length: 404 Bit Score: 366.86 E-value: 5.45e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 1 MSKLVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADLgAGAAHQEALDFIVNKILPLNPEL 80
Cdd:PRK12397 1 MSYKIMAINAGSSSLKFQLLEMPQGDMLCQGLIERIGMADAQVTIKTHSQKWQETV-PVADHRDAVTLLLEKLLGYQIIN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 81 S-KNLIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQTMPEE 159
Cdd:PRK12397 80 SlRDIDGVGHRVAHGGEFFKDSTLVTDETLAQIERLAELAPLHNPVNALGIHVFRQLLPDA--PSVAVFDTAFHQTLDEP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 160 AFLYALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVM 239
Cdd:PRK12397 158 AYIYPLPWRYYAELGIRRYGFHGTSHKYVSGVLAEKLGVPLSALRVICCHLGNGSSICAIKNGRSVNTSMGFTPQSGVMM 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 240 GTRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYDS-KEEAKRAMDVYCYRLAKYIGAYAA 318
Cdd:PRK12397 238 GTRSGDIDPSILPWIAQREGKTPQQLNQLLNNESGLLGVSGVSSDYRDVEQAANTgNRQAKLALTLFAERIRATIGSYIM 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 319 AMDGrLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLK-ARFGKggeiTKAGSTKALVIPTNEEWVIAHDALEL 397
Cdd:PRK12397 318 QMGG-LDALVFTGGIGENSARARSAVCHNLQFLGLAVDEEKNQRnATFIQ----TENALVKVAVINTNEELMIAQDVMRI 392
|
|
| PRK07157 |
PRK07157 |
acetate kinase; Provisional |
1-397 |
1.57e-120 |
|
acetate kinase; Provisional
Pssm-ID: 235948 Cd Length: 400 Bit Score: 355.20 E-value: 1.57e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 1 MSKLVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADLGAgAAHQEALDFIV-----NKILp 75
Cdd:PRK07157 1 MKAKILVINAGSSSIKWQLFDKENLNLIASGLAERIGLENGLIKIKFGKKKYEKEVDM-PNHKVAVAVLIeiweeNKLI- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 76 lnpELSKNLIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALadKNVAVFDTAFHQT 155
Cdd:PRK07157 79 ---EDLEEIELIGFRVVHGGDYFNGPTKLDDKEISKIEKVAKYAPLHNPGALQTIKAFKKVLPKA--KLSASFDTAFHTS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 156 MPEEAFLYALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKpvEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLE 235
Cdd:PRK07157 154 IPKINYTYPINYEIAKKYGIKKYGFHGISHKFITNKVEKILNK--DKVNFVNLHIGNGASLCAIKNSKSIDTSMGLTPLA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 236 GLVMGTRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYDS-KEEAKRAMDVYCYRLAKYIG 314
Cdd:PRK07157 232 GVMMGTRSGDIDPSIHEFVAKEANMSISEFTDLLNKKSGLLGVSGISSDLRDVIKAAESgNKRAKFALDLYAQKIVDYLA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 315 AYAAAMDGRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLK--ARFGKGGEI-TKAGSTKALVIPTNEEWVIA 391
Cdd:PRK07157 312 NYINKIGKKIDAIVFTAGVGENSAFVRELVINKINIPNIKLDKEKNLKkiGEYGPIELIsTPDSDIPVYVIRTNEELLIA 391
|
....*.
gi 491491476 392 HDALEL 397
Cdd:PRK07157 392 KNAIKL 397
|
|
| PRK07058 |
PRK07058 |
acetate/propionate family kinase; |
1-400 |
3.60e-93 |
|
acetate/propionate family kinase;
Pssm-ID: 235922 Cd Length: 396 Bit Score: 285.02 E-value: 3.60e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 1 MSKLVLVLNCGSSSLKFAVIDATTGDDLLSGLAEcFNLDDARIKWKLNGEKGSADLGAGAAHQEALDFIVNKILPLnpeL 80
Cdd:PRK07058 2 SKPLLLTFNAGSSTVKIGLFEVDGNEARRIGKGD-IDFRRAPLRFHLRNGGETLDIPLKASVTDDLHTVLDETFDW---L 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 81 SKN-----LIAIGHRVVHGGERFTSSVVICEDVIAGIEAAVPYAPLHNPAHLIGIREARRVFPALAdkNVAVFDTAFHQT 155
Cdd:PRK07058 78 AAHfdvseLVAVGHRVVHGGDRFAGAVLIDDATLDAIEALVPLAPLHQPQSLRLIRAIRHLRPHLP--QTASFDTAFHRT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 156 MPEEAFLYALPYKLYKEnGIRRYGAHGTSHYYISLEAAKQlNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLE 235
Cdd:PRK07058 156 QPDLVRRFAIPRALHDE-GIKRYGFHGLSYKFVAGELRRR-APELARGKVVAAHLGSGASLCALDAGKSRDTSMGFSTLD 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 236 GLVMGTRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDnyDSKEEAKRAMDVYCYRLAKYIGA 315
Cdd:PRK07058 234 GIPMATRCGALDPGVVLHLLKQEGMSLDEVEDLLYHRSGLLGVSGISGDTRDLLA--SDAPEAREALDLFALRIAGEIAR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 316 YAAAMDGrLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLKARFgkggEITKAGS-TKALVIPTNEEWVIAHDA 394
Cdd:PRK07058 312 LAATLGG-LDAVVFTAGIGEHQPAIRAAVCERLAWLGVELDPAANAANAF----TISSRTSrVAAFVIPTDEEQVIADEA 386
|
....*.
gi 491491476 395 LELVGA 400
Cdd:PRK07058 387 FSVLRA 392
|
|
| ASKHA_NBD_BK |
cd24011 |
nucleotide-binding domain (NBD) of the butyrate kinase (BK) domain family; Butyrate kinase (EC ... |
156-333 |
4.87e-30 |
|
nucleotide-binding domain (NBD) of the butyrate kinase (BK) domain family; Butyrate kinase (EC 2.7.2.7) catalyzes the formation of butyryl-CoA by phosphorylating butyrate in the presence of ATP to form butyryl phosphate. Butyrate kinases exist in many fermentative species of the bacterial and archaeal families. They belong to the ASKHA (Acetate and Sugar Kinases/Hsc70/Actin) superfamily of phosphotransferases, all members of which share a common characteristic five-stranded beta sheet occurring in both the N- and C-terminal domains.
Pssm-ID: 466861 Cd Length: 345 Bit Score: 118.41 E-value: 4.87e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 156 MPEEAFLYALPyklykenGIRRYGA-HGTSHYYISLEAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLtPL 234
Cdd:cd24011 133 MDPVARITGIP-------EIERRSIfHALNQKAVARRAAKELGKPYEELNLIVAHLGGGISVGAHRKGRVIDVNNAL-DG 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 235 EGlVMGT-RSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEvTSDCRFVEDNYDS-KEEAKRAMDVYCYRLAKY 312
Cdd:cd24011 205 EG-PFSPeRAGTLPVGDLIKLCFSGKYTLEELKKKLKGKGGLVAYLG-TNDFREVEKRIEAgDEKAKLVLDAMAYQIAKE 282
|
170 180
....*....|....*....|.
gi 491491476 313 IGAYAAAMDGRLDAVVFTGGI 333
Cdd:cd24011 283 IGALAAVLKGKVDAIILTGGL 303
|
|
| PRK03011 |
PRK03011 |
butyrate kinase; Provisional |
191-333 |
8.26e-23 |
|
butyrate kinase; Provisional
Pssm-ID: 235099 Cd Length: 358 Bit Score: 98.31 E-value: 8.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491491476 191 EAAKQLNKPVEELNIINCHLGNGGSVCAIKNGKSVDTSMGLtPLEGLVMGTRSGDLdPAIIFFlhdKLGMSV----ADIN 266
Cdd:PRK03011 164 RVAKELGKKYEELNLIVAHLGGGISVGAHRKGRVIDVNNAL-DGEGPFSPERAGGL-PVGDLV---ELCFSGkytkEELK 238
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491491476 267 TMLTKESGLQGLTEvTSDCRFVEDNYDSK-EEAKRAMDVYCYRLAKYIGAYAAAMDGRLDAVVFTGGI 333
Cdd:PRK03011 239 KKLVGKGGLVAYLG-TNDAREVEKRIEEGdEKAKLVYEAMAYQIAKEIGAMAAVLKGKVDAIVLTGGL 305
|
|
| |
