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Conserved domains on  [gi|491550993|ref|WP_005408584|]
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MULTISPECIES: cytochrome o ubiquinol oxidase subunit IV [Stenotrophomonas]

Protein Classification

cytochrome o ubiquinol/quinol oxidase subunit IV( domain architecture ID 10006944)

cytochrome o ubiquinol/quinol oxidase subunit IV such as cytochrome o ubiquinol oxidase subunit IV that is a component of the terminal oxidase of the aerobic respiratory chain that has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CyoD COG3125
Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Energy production and conversion];
7-113 9.04e-39

Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Energy production and conversion];


:

Pssm-ID: 442359  Cd Length: 109  Bit Score: 125.70  E-value: 9.04e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491550993   7 AHDHGTGGESHGTVKSYLIGFVLAVVLTVIPFWMVMSGDFSRTVNGVVIAITAVLQMLVHLVFFLHLDRSSESRWNVNAA 86
Cdd:COG3125    2 SHHHHHEGASHGSLKSYLIGFVLSVILTAIPFWLVMTGALSPGTTLAVILGLAVVQIVVHLVYFLHMNTSSEGRWNLLAL 81

                         90       100
                 ....*....|....*....|....*..
gi 491550993  87 AFTVVVIGIIVVGTLWVMHNMNVHMMH 113
Cdd:COG3125   82 IFTVLIVVIVVGGSLWIMYHLNYNMMP 108
 
Name Accession Description Interval E-value
CyoD COG3125
Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Energy production and conversion];
7-113 9.04e-39

Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Energy production and conversion];


Pssm-ID: 442359  Cd Length: 109  Bit Score: 125.70  E-value: 9.04e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491550993   7 AHDHGTGGESHGTVKSYLIGFVLAVVLTVIPFWMVMSGDFSRTVNGVVIAITAVLQMLVHLVFFLHLDRSSESRWNVNAA 86
Cdd:COG3125    2 SHHHHHEGASHGSLKSYLIGFVLSVILTAIPFWLVMTGALSPGTTLAVILGLAVVQIVVHLVYFLHMNTSSEGRWNLLAL 81

                         90       100
                 ....*....|....*....|....*..
gi 491550993  87 AFTVVVIGIIVVGTLWVMHNMNVHMMH 113
Cdd:COG3125   82 IFTVLIVVIVVGGSLWIMYHLNYNMMP 108
CyoD TIGR02847
cytochrome o ubiquinol oxidase subunit IV; Cytochrome o terminal oxidase complex is the ...
 17-112 3.32e-33

cytochrome o ubiquinol oxidase subunit IV; Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport]


Pssm-ID: 131894  Cd Length: 96  Bit Score: 111.17  E-value: 3.32e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491550993   17 HGTVKSYLIGFVLAVVLTVIPFWMVMSGDFSRTVNGVVIAITAVLQMLVHLVFFLHLDRSSESRWNVNAAAFTVVVIGII 96
Cdd:TIGR02847   1 HGSLKSYLIGFVLSVILTAIPFGLVMSGTLSKGLTLVIIIVLAVVQILVHLVFFLHLNTSSEQRWNLISLLFTILIIFIL 80

                          90
                  ....*....|....*.
gi 491550993   97 VVGTLWVMHNMNVHMM 112
Cdd:TIGR02847  81 IGGSIWIMHNLNHNMM 96
PRK10582 PRK10582
cytochrome o ubiquinol oxidase subunit IV; Provisional
 7-112 4.95e-29

cytochrome o ubiquinol oxidase subunit IV; Provisional


Pssm-ID: 182568  Cd Length: 109  Bit Score: 100.99  E-value: 4.95e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491550993   7 AHDHGTGGESHGTVKSYLIGFVLAVVLTVIPFWMVMSGDFSRTVNGVVIAITAVLQMLVHLVFFLHLDRSSESRWNVNAA 86
Cdd:PRK10582   2 SHSTDHGGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPAVILGTILAMAVVQILVHLVCFLHMNTKSDEGWNMTAF 81

                         90       100
                 ....*....|....*....|....*.
gi 491550993  87 AFTVVVIGIIVVGTLWVMHNMNVHMM 112
Cdd:PRK10582  82 VFTVLIIAILVVGSIWIMWNLNYNMM 107
COX4_pro pfam03626
Prokaryotic Cytochrome C oxidase subunit IV; Cytochrome c oxidase (COX) is a multi-subunit ...
 24-89 1.47e-07

Prokaryotic Cytochrome C oxidase subunit IV; Cytochrome c oxidase (COX) is a multi-subunit enzyme complex that catalyzes the final step of electron transfer through the respiratory chain on the mitochondrial inner membrane. This family is composed of cytochrome c oxidase subunit 4 from prokaryotes.


Pssm-ID: 427408  Cd Length: 72  Bit Score: 45.16  E-value: 1.47e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491550993   24 LIGFVLAVVLTVIPFWMVMsGDFSRTVNGVVIAITAVLQMLVHLVFFLHLdRSSESRWNVNAAAFT 89
Cdd:pfam03626   1 LIVFVLLLILTAITFALVY-AGLGGLAAIIAILVLAVVKALLILLYFMHL-KEEPRLWRLLALIFL 64
 
Name Accession Description Interval E-value
CyoD COG3125
Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Energy production and conversion];
7-113 9.04e-39

Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Energy production and conversion];


Pssm-ID: 442359  Cd Length: 109  Bit Score: 125.70  E-value: 9.04e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491550993   7 AHDHGTGGESHGTVKSYLIGFVLAVVLTVIPFWMVMSGDFSRTVNGVVIAITAVLQMLVHLVFFLHLDRSSESRWNVNAA 86
Cdd:COG3125    2 SHHHHHEGASHGSLKSYLIGFVLSVILTAIPFWLVMTGALSPGTTLAVILGLAVVQIVVHLVYFLHMNTSSEGRWNLLAL 81

                         90       100
                 ....*....|....*....|....*..
gi 491550993  87 AFTVVVIGIIVVGTLWVMHNMNVHMMH 113
Cdd:COG3125   82 IFTVLIVVIVVGGSLWIMYHLNYNMMP 108
CyoD TIGR02847
cytochrome o ubiquinol oxidase subunit IV; Cytochrome o terminal oxidase complex is the ...
 17-112 3.32e-33

cytochrome o ubiquinol oxidase subunit IV; Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport]


Pssm-ID: 131894  Cd Length: 96  Bit Score: 111.17  E-value: 3.32e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491550993   17 HGTVKSYLIGFVLAVVLTVIPFWMVMSGDFSRTVNGVVIAITAVLQMLVHLVFFLHLDRSSESRWNVNAAAFTVVVIGII 96
Cdd:TIGR02847   1 HGSLKSYLIGFVLSVILTAIPFGLVMSGTLSKGLTLVIIIVLAVVQILVHLVFFLHLNTSSEQRWNLISLLFTILIIFIL 80

                          90
                  ....*....|....*.
gi 491550993   97 VVGTLWVMHNMNVHMM 112
Cdd:TIGR02847  81 IGGSIWIMHNLNHNMM 96
PRK10582 PRK10582
cytochrome o ubiquinol oxidase subunit IV; Provisional
 7-112 4.95e-29

cytochrome o ubiquinol oxidase subunit IV; Provisional


Pssm-ID: 182568  Cd Length: 109  Bit Score: 100.99  E-value: 4.95e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491550993   7 AHDHGTGGESHGTVKSYLIGFVLAVVLTVIPFWMVMSGDFSRTVNGVVIAITAVLQMLVHLVFFLHLDRSSESRWNVNAA 86
Cdd:PRK10582   2 SHSTDHGGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPAVILGTILAMAVVQILVHLVCFLHMNTKSDEGWNMTAF 81

                         90       100
                 ....*....|....*....|....*.
gi 491550993  87 AFTVVVIGIIVVGTLWVMHNMNVHMM 112
Cdd:PRK10582  82 VFTVLIIAILVVGSIWIMWNLNYNMM 107
COX4_pro pfam03626
Prokaryotic Cytochrome C oxidase subunit IV; Cytochrome c oxidase (COX) is a multi-subunit ...
 24-89 1.47e-07

Prokaryotic Cytochrome C oxidase subunit IV; Cytochrome c oxidase (COX) is a multi-subunit enzyme complex that catalyzes the final step of electron transfer through the respiratory chain on the mitochondrial inner membrane. This family is composed of cytochrome c oxidase subunit 4 from prokaryotes.


Pssm-ID: 427408  Cd Length: 72  Bit Score: 45.16  E-value: 1.47e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491550993   24 LIGFVLAVVLTVIPFWMVMsGDFSRTVNGVVIAITAVLQMLVHLVFFLHLdRSSESRWNVNAAAFT 89
Cdd:pfam03626   1 LIVFVLLLILTAITFALVY-AGLGGLAAIIAILVLAVVKALLILLYFMHL-KEEPRLWRLLALIFL 64
QoxD TIGR02901
cytochrome aa3 quinol oxidase, subunit IV; This family (QoxD) encodes subunit IV of the ...
 22-104 4.13e-06

cytochrome aa3 quinol oxidase, subunit IV; This family (QoxD) encodes subunit IV of the aa3-type quinone oxidase, one of several bacterial terminal oxidases. This complex couples oxidation of reduced quinones with the reduction of molecular oxygen to water and the pumping of protons to form a proton gradient utilized for ATP production. aa3-type oxidases contain two heme a cofactors as well as copper atoms in the active site. [Energy metabolism, Electron transport]


Pssm-ID: 200218  Cd Length: 94  Bit Score: 41.65  E-value: 4.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491550993   22 SYLIGFVLAVVLTVIPFWMVMSGDFSRTVNGVVIAITAVLQMLVHLVFFLHLDRSSESRWNVNAAAFTVVVIGIIVVGTL 101
Cdd:TIGR02901   8 KHVMGFILSLILTLLALWVAFYSDLSLVVGLTIIIVFAFIQASLQLIVFMHINEGNDGKVQIYNIGYAAFIALVTVFGSL 87


                  ...
gi 491550993  102 WVM 104
Cdd:TIGR02901  88 WVM 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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