|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
1-747 |
0e+00 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 1428.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 1 MLSQLREIVEKVSRVDDVHLALDILVKETCAALCTECCTIYLANEEMQRLELMATQGL-IFEGDSIHINFNEGLVGLVKR 79
Cdd:PRK11061 1 MLTRLREIVEKVASAPRLNEALDILVTETCLAMDTEVCSVYLADHDRRCYYLMATRGLkKPRGRTVTLAFDEGIVGLVGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 80 SAEPLNLAEASTHPDFKFFPQLGEQVYHSFLGTPIIHRKQVLGVLVIQQKTPRLFSEMEESFLVTLSAQLAVLIAHAQNL 159
Cdd:PRK11061 81 LAEPINLADAQKHPSFKYIPSVKEERFRAFLGVPIIYRRQLLGVLVVQQRELRQFDESEESFLVTLATQLAAILSQSQLT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 160 GHWQLASKpTVIKGLPASTGVAIGEFWFDNTQPNLNDVFPASALDKEREHELLAVAVERALSDFRRMRKKFDSEINKDAL 239
Cdd:PRK11061 161 ALFGQYRQ-TRIRALPASPGVAIAEGWQDATQPLLEQVYPASTLDPALERERLTGALEEAANEFRRYSKRFAAGAQKETA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 240 AIFDLFTHLLNDPMLRGDLKKQIEKGDRADWALRQVVETYSNRFARMSDVYLRERAQDIRELGQRLLYFLHNSEQEHASI 319
Cdd:PRK11061 240 AIFDLYSHLLNDPRLRRELFAEVDKGSVAEWAVKQVIEKFAEQFAALSDNYLRERAGDLRALGQRLLFHLDDSEQGPNAW 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 320 DRPVILVANELTATLLASIPKQHLLAVVSLEGAANSHAAILSRALGVPAIMGANINTSVVNGKKGIVDGYTGEIYLEPNR 399
Cdd:PRK11061 320 PERFILVADELTATLLAELPQDRLAGVVVRDGAANSHAAILVRALGIPTVMGADIQPSLLHQRLLIVDGYRGELLVDPEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 400 QLLREYRSLVSEESELFAMVNKDLALPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQ 479
Cdd:PRK11061 400 VLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSAEHEEKLGSRVDGVGLYRTEIPFMLQSGFPSEEEQ 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 480 YHQYQAILNSYPNQRVVMRTLDIGGDKPLPYLPIDEDNPFLGWRGIRFTLDHPDIFLIQLRAMLRASAESGNLSILLPMV 559
Cdd:PRK11061 480 VAQYQGMLQMFPDKPVTLRTLDIGADKQLPYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLSILLPMV 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 560 SGIKELDDAITLINQAYSEVV-LLDERIQAPKVGVMIEVPSMVYLLPAIAHRVDFVSVGTNDLTQYLLAVDRNNSRVADV 638
Cdd:PRK11061 560 TSIDEVDEARRLIDRAGREVEeMLGYEIPKPRIGIMIEVPSMVFMLPHLASRVDFISVGTNDLTQYLLAVDRNNTRVASL 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 639 YESMHPAVLLALKQIHDVCLQYQVPVCICGELAGDPFGALLLLGLGYNSLSMNTSNVAKVKYLIRHSQQKELEKLVEKAM 718
Cdd:PRK11061 640 YDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGDPMGALLLIGLGYRHLSMNGRSVARVKYLLRHIDLAEAENLAQRSL 719
|
730 740
....*....|....*....|....*....
gi 491590344 719 SCSYGQEIHQMMHDFFIQQGFAGFIRAGK 747
Cdd:PRK11061 720 EAQLATEVRHQVAAFMERRGLGGLIRGGK 748
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
171-734 |
0e+00 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 583.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 171 IKGLPASTGVAIGE-FWFDNTQPNLNDVFPASAlDKEREHELLAVAVERALSDFRRMRKKFDSEINKDALAIFDlfTHL- 248
Cdd:COG1080 1 LKGIAASPGIAIGKaFLLREEDLEVPEYTISPE-DVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFD--AHLl 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 249 -LNDPMLRGDLKKQIEKGDR-ADWALRQVVETYSNRFARMSDVYLRERAQDIRELGQRLLYFLHN-SEQEHASIDRPVIL 325
Cdd:COG1080 78 lLEDPELIEEVEELIREGRYnAEWALKEVIEELAAQFEALDDEYLRERAADIRDVGRRVLRNLLGvEAPDLSDLPEPVIL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 326 VANELTATLLASIPKQHLLAVVSLEGAANSHAAILSRALGVPAIMGA-NINTSVVNGKKGIVDGYTGEIYLEPNRQLLRE 404
Cdd:COG1080 158 VAHDLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLgDALLLVKDGDLVIVDGDAGVVIVNPDEETLAE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 405 YRSLVSEESELFAMVNKDLALPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQYHQYQ 484
Cdd:COG1080 238 YRERQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYR 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 485 AILNSYPNQRVVMRTLDIGGDKPLPYLPI-DEDNPFLGWRGIRFTLDHPDIFLIQLRAMLRASAEsGNLSILLPMVSGIK 563
Cdd:COG1080 318 AVAEAMGGRPVTIRTLDIGGDKPLPYLPLpKEENPFLGLRAIRLCLDRPELFRTQLRAILRASAH-GNLRIMFPMISSVE 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 564 ELDDAITLINQAYSEvvLLDERI---QAPKVGVMIEVPSMVYLLPAIAHRVDFVSVGTNDLTQYLLAVDRNNSRVADVYE 640
Cdd:COG1080 397 ELRQAKALLEEAKAE--LRAEGIpfdEDIPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYD 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 641 SMHPAVLLALKQIHDVCLQYQVPVCICGELAGDPFGALLLLGLGYNSLSMNTSNVAKVKYLIRHSQQKELEKLVEKAMSC 720
Cdd:COG1080 475 PLHPAVLRLIKMVIDAAHKAGKPVGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAVKAIIRRLDLAEARALAEKALAL 554
|
570
....*....|....
gi 491590344 721 SYGQEIHQMMHDFF 734
Cdd:COG1080 555 DTAEEVRALLEEFL 568
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
171-730 |
5.26e-124 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 382.22 E-value: 5.26e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 171 IKGLPASTGVAIGEFWFDNTQPNLNDVFPASALDKEREHELLAVAVERALSDFRRMRKKFDSEINKDALAIFDLFTHLLN 250
Cdd:TIGR01417 1 ISGIGVSPGIAIGKALLLKKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 251 DPMLRGDLKKQIEKGDR-ADWALRQVVETYSNRFARMSDVYLRERAQDIRELGQRLLYFLHNSEQEHAS-IDRPVILVAN 328
Cdd:TIGR01417 81 DPELTEEVIELIKKDHKnAEFAAHEVFEGQAKSLEEMDDEYLKERAADIRDIGNRLLGHLLGVKISDLSeIQDEVILVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 329 ELTATLLASIPKQHLLAVVSLEGAANSHAAILSRALGVPAIMG-ANINTSVVNGKKGIVDGYTGEIYLEPNRQLLREYRS 407
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGtKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYEA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 408 LVSEESELFAMVNKDLALPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQYHQYQAIL 487
Cdd:TIGR01417 241 KQEAVSSEKAELAKLKDKPAITLDGHQVELAANIGTVDDVEGAERNGGEGIGLFRTEFLYMSRDQLPTEEEQFAAYKTVL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 488 NSYPNQRVVMRTLDIGGDKPLPYLPI-DEDNPFLGWRGIRFTLDHPDIFLIQLRAMLRASAEsGNLSILLPMVSGIKELD 566
Cdd:TIGR01417 321 EAMESDAVIVRTLDIGGDKELPYLNFpKEENPFLGYRAIRLALEREEILRTQLRAILRASAY-GKLRIMFPMVATVEEIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 567 DAITLINQaysEVVLLDERIQAP----KVGVMIEVPSMVYLLPAIAHRVDFVSVGTNDLTQYLLAVDRNNSRVADVYESM 642
Cdd:TIGR01417 400 AVKQELEE---EKQELNDEGKAFdeniEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDRGNDLISNLYQPY 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 643 HPAVLLALKQIHDVCLQYQVPVCICGELAGDPFGALLLLGLGYNSLSMNTSNVAKVKYLIRHSQQKELEKLVEKAMSCSY 722
Cdd:TIGR01417 477 NPAVLRLIKLVIDAAKAEGIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIKMIIRKLNIEECKSLAEKALAQPT 556
|
....*...
gi 491590344 723 GQEIHQMM 730
Cdd:TIGR01417 557 TEEVHKLV 564
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
417-706 |
2.22e-108 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 331.58 E-value: 2.22e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 417 AMVNKDLALPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQYHQYQAILNSYPNQRVV 496
Cdd:pfam02896 2 AELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDEQFEAYKGVLEAMNGRPVT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 497 MRTLDIGGDKPLPYLPID-EDNPFLGWRGIRFTLDHPDIFLIQLRAMLRASAEsGNLSILLPMVSGIKELDDAITLINQA 575
Cdd:pfam02896 82 VRTLDIGGDKELPYLEEPeEMNPFLGWRGIRIGLDRPELFRTQLRAILRASAF-GNLRIMFPMVASVEELREAKAIIEEV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 576 YSEVVLLDERIQAPKVGVMIEVPSMVYLLPAIAHRVDFVSVGTNDLTQYLLAVDRNNSRVADVYESMHPAVLLALKQIHD 655
Cdd:pfam02896 161 KEELDAEVGFDKDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNERVAYLYDPLHPAVLRLIKEVIR 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 491590344 656 VCLQYQVPVCICGELAGDPFGALLLLGLGYNSLSMNTSNVAKVKYLIRHSQ 706
Cdd:pfam02896 241 AAHRHGKWVGICGEMAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQID 291
|
|
| GAF |
smart00065 |
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these ... |
17-157 |
4.45e-18 |
|
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these domains in PDE6B result in autosomal recessive inheritance of retinitis pigmentosa.
Pssm-ID: 214500 [Multi-domain] Cd Length: 149 Bit Score: 81.66 E-value: 4.45e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 17 DVHLALDILVKETCAALCTECCTIYLANE-EMQRLELMATQGLIFEGDSIHINFNEGLVGLVKRSAEPLNLAEASTHPDF 95
Cdd:smart00065 1 DLEELLQTILEELRQLLGADRVLIYLVDEnDRGELVLVAADGLTLPTLGIRFPLDEGLAGRVAETGRPLNIPDVEADPLF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491590344 96 KFFPQLGEQVYHSFLGTPIIHRKQVLGVLVIQQKT-PRLFSEMEESFLVTLSAQLAVLIAHAQ 157
Cdd:smart00065 81 AEDLLGRYQGVRSFLAVPLVADGELVGVLALHNKKsPRPFTEEDEELLQALANQLAIALANAQ 143
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
1-747 |
0e+00 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 1428.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 1 MLSQLREIVEKVSRVDDVHLALDILVKETCAALCTECCTIYLANEEMQRLELMATQGL-IFEGDSIHINFNEGLVGLVKR 79
Cdd:PRK11061 1 MLTRLREIVEKVASAPRLNEALDILVTETCLAMDTEVCSVYLADHDRRCYYLMATRGLkKPRGRTVTLAFDEGIVGLVGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 80 SAEPLNLAEASTHPDFKFFPQLGEQVYHSFLGTPIIHRKQVLGVLVIQQKTPRLFSEMEESFLVTLSAQLAVLIAHAQNL 159
Cdd:PRK11061 81 LAEPINLADAQKHPSFKYIPSVKEERFRAFLGVPIIYRRQLLGVLVVQQRELRQFDESEESFLVTLATQLAAILSQSQLT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 160 GHWQLASKpTVIKGLPASTGVAIGEFWFDNTQPNLNDVFPASALDKEREHELLAVAVERALSDFRRMRKKFDSEINKDAL 239
Cdd:PRK11061 161 ALFGQYRQ-TRIRALPASPGVAIAEGWQDATQPLLEQVYPASTLDPALERERLTGALEEAANEFRRYSKRFAAGAQKETA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 240 AIFDLFTHLLNDPMLRGDLKKQIEKGDRADWALRQVVETYSNRFARMSDVYLRERAQDIRELGQRLLYFLHNSEQEHASI 319
Cdd:PRK11061 240 AIFDLYSHLLNDPRLRRELFAEVDKGSVAEWAVKQVIEKFAEQFAALSDNYLRERAGDLRALGQRLLFHLDDSEQGPNAW 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 320 DRPVILVANELTATLLASIPKQHLLAVVSLEGAANSHAAILSRALGVPAIMGANINTSVVNGKKGIVDGYTGEIYLEPNR 399
Cdd:PRK11061 320 PERFILVADELTATLLAELPQDRLAGVVVRDGAANSHAAILVRALGIPTVMGADIQPSLLHQRLLIVDGYRGELLVDPEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 400 QLLREYRSLVSEESELFAMVNKDLALPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQ 479
Cdd:PRK11061 400 VLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSAEHEEKLGSRVDGVGLYRTEIPFMLQSGFPSEEEQ 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 480 YHQYQAILNSYPNQRVVMRTLDIGGDKPLPYLPIDEDNPFLGWRGIRFTLDHPDIFLIQLRAMLRASAESGNLSILLPMV 559
Cdd:PRK11061 480 VAQYQGMLQMFPDKPVTLRTLDIGADKQLPYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLSILLPMV 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 560 SGIKELDDAITLINQAYSEVV-LLDERIQAPKVGVMIEVPSMVYLLPAIAHRVDFVSVGTNDLTQYLLAVDRNNSRVADV 638
Cdd:PRK11061 560 TSIDEVDEARRLIDRAGREVEeMLGYEIPKPRIGIMIEVPSMVFMLPHLASRVDFISVGTNDLTQYLLAVDRNNTRVASL 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 639 YESMHPAVLLALKQIHDVCLQYQVPVCICGELAGDPFGALLLLGLGYNSLSMNTSNVAKVKYLIRHSQQKELEKLVEKAM 718
Cdd:PRK11061 640 YDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGDPMGALLLIGLGYRHLSMNGRSVARVKYLLRHIDLAEAENLAQRSL 719
|
730 740
....*....|....*....|....*....
gi 491590344 719 SCSYGQEIHQMMHDFFIQQGFAGFIRAGK 747
Cdd:PRK11061 720 EAQLATEVRHQVAAFMERRGLGGLIRGGK 748
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
171-734 |
0e+00 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 583.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 171 IKGLPASTGVAIGE-FWFDNTQPNLNDVFPASAlDKEREHELLAVAVERALSDFRRMRKKFDSEINKDALAIFDlfTHL- 248
Cdd:COG1080 1 LKGIAASPGIAIGKaFLLREEDLEVPEYTISPE-DVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFD--AHLl 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 249 -LNDPMLRGDLKKQIEKGDR-ADWALRQVVETYSNRFARMSDVYLRERAQDIRELGQRLLYFLHN-SEQEHASIDRPVIL 325
Cdd:COG1080 78 lLEDPELIEEVEELIREGRYnAEWALKEVIEELAAQFEALDDEYLRERAADIRDVGRRVLRNLLGvEAPDLSDLPEPVIL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 326 VANELTATLLASIPKQHLLAVVSLEGAANSHAAILSRALGVPAIMGA-NINTSVVNGKKGIVDGYTGEIYLEPNRQLLRE 404
Cdd:COG1080 158 VAHDLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLgDALLLVKDGDLVIVDGDAGVVIVNPDEETLAE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 405 YRSLVSEESELFAMVNKDLALPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQYHQYQ 484
Cdd:COG1080 238 YRERQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYR 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 485 AILNSYPNQRVVMRTLDIGGDKPLPYLPI-DEDNPFLGWRGIRFTLDHPDIFLIQLRAMLRASAEsGNLSILLPMVSGIK 563
Cdd:COG1080 318 AVAEAMGGRPVTIRTLDIGGDKPLPYLPLpKEENPFLGLRAIRLCLDRPELFRTQLRAILRASAH-GNLRIMFPMISSVE 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 564 ELDDAITLINQAYSEvvLLDERI---QAPKVGVMIEVPSMVYLLPAIAHRVDFVSVGTNDLTQYLLAVDRNNSRVADVYE 640
Cdd:COG1080 397 ELRQAKALLEEAKAE--LRAEGIpfdEDIPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYD 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 641 SMHPAVLLALKQIHDVCLQYQVPVCICGELAGDPFGALLLLGLGYNSLSMNTSNVAKVKYLIRHSQQKELEKLVEKAMSC 720
Cdd:COG1080 475 PLHPAVLRLIKMVIDAAHKAGKPVGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAVKAIIRRLDLAEARALAEKALAL 554
|
570
....*....|....
gi 491590344 721 SYGQEIHQMMHDFF 734
Cdd:COG1080 555 DTAEEVRALLEEFL 568
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
171-730 |
5.26e-124 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 382.22 E-value: 5.26e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 171 IKGLPASTGVAIGEFWFDNTQPNLNDVFPASALDKEREHELLAVAVERALSDFRRMRKKFDSEINKDALAIFDLFTHLLN 250
Cdd:TIGR01417 1 ISGIGVSPGIAIGKALLLKKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 251 DPMLRGDLKKQIEKGDR-ADWALRQVVETYSNRFARMSDVYLRERAQDIRELGQRLLYFLHNSEQEHAS-IDRPVILVAN 328
Cdd:TIGR01417 81 DPELTEEVIELIKKDHKnAEFAAHEVFEGQAKSLEEMDDEYLKERAADIRDIGNRLLGHLLGVKISDLSeIQDEVILVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 329 ELTATLLASIPKQHLLAVVSLEGAANSHAAILSRALGVPAIMG-ANINTSVVNGKKGIVDGYTGEIYLEPNRQLLREYRS 407
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGtKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYEA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 408 LVSEESELFAMVNKDLALPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQYHQYQAIL 487
Cdd:TIGR01417 241 KQEAVSSEKAELAKLKDKPAITLDGHQVELAANIGTVDDVEGAERNGGEGIGLFRTEFLYMSRDQLPTEEEQFAAYKTVL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 488 NSYPNQRVVMRTLDIGGDKPLPYLPI-DEDNPFLGWRGIRFTLDHPDIFLIQLRAMLRASAEsGNLSILLPMVSGIKELD 566
Cdd:TIGR01417 321 EAMESDAVIVRTLDIGGDKELPYLNFpKEENPFLGYRAIRLALEREEILRTQLRAILRASAY-GKLRIMFPMVATVEEIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 567 DAITLINQaysEVVLLDERIQAP----KVGVMIEVPSMVYLLPAIAHRVDFVSVGTNDLTQYLLAVDRNNSRVADVYESM 642
Cdd:TIGR01417 400 AVKQELEE---EKQELNDEGKAFdeniEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDRGNDLISNLYQPY 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 643 HPAVLLALKQIHDVCLQYQVPVCICGELAGDPFGALLLLGLGYNSLSMNTSNVAKVKYLIRHSQQKELEKLVEKAMSCSY 722
Cdd:TIGR01417 477 NPAVLRLIKLVIDAAKAEGIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIKMIIRKLNIEECKSLAEKALAQPT 556
|
....*...
gi 491590344 723 GQEIHQMM 730
Cdd:TIGR01417 557 TEEVHKLV 564
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
171-733 |
2.26e-114 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 357.40 E-value: 2.26e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 171 IKGLPASTGVAIGEFWFDNTQPNLNDVFPASALDKEREHELLAVAVERALSDFRRMRKKFDSEINKDALAIFDLFTHLLN 250
Cdd:PRK11177 2 ISGILASPGIAFGKALLLKEDEIVINRKKISADQVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLLE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 251 DPMLRGDLKKQI-EKGDRADWALRQVVETYSNRFARMSDVYLRERAQDIRELGQRLLY-FLHNSEQEHASIDRPVILVAN 328
Cdd:PRK11177 82 DEELEQEIIALIkDKHMTADAAAHSVIEGQAKALEELDDEYLKERAADVRDIGKRLLKnILGLKIIDLSAIQEEVILVAA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 329 ELTATLLASIPKQHLLAVVSLEGAANSHAAILSRALGVPAIMGA-NINTSVVNGKKGIVDGYTGEIYLEPNRQLLREYRS 407
Cdd:PRK11177 162 DLTPSETAQLNLKKVLGFITDIGGRTSHTSIMARSLELPAIVGTgNITKQVKNGDYLILDAVNNQIYVNPTNEVIEELKA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 408 L----VSEESELFAMvnKDLalPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQYHQY 483
Cdd:PRK11177 242 VqeqyASEKAELAKL--KDL--PAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFQAY 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 484 QAILNSYPNQRVVMRTLDIGGDKPLPY--LPiDEDNPFLGWRGIRFTLDHPDIFLIQLRAMLRASAeSGNLSILLPM--- 558
Cdd:PRK11177 318 KAVAEAMGSQAVIVRTMDIGGDKELPYmnLP-KEENPFLGWRAIRIAMDRKEILHDQLRAILRASA-FGKLRIMFPMiis 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 559 VSGIKELDDAI-TLINQAYSEVVLLDERIQapkVGVMIEVPSMVyllpAIAH----RVDFVSVGTNDLTQYLLAVDRNNS 633
Cdd:PRK11177 396 VEEVRELKAEIeILKQELRDEGKAFDESIE---IGVMVETPAAA----VIARhlakEVDFFSIGTNDLTQYTLAVDRGNE 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 634 RVADVYESMHPAVLLALKQIHDVCLQYQVPVCICGELAGDPFGALLLLGLGYNSLSMNTSNVAKVKYLIRHSQQKELEKL 713
Cdd:PRK11177 469 LISHLYNPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKAL 548
|
570 580
....*....|....*....|
gi 491590344 714 VEKAMSCSYGQEIHQMMHDF 733
Cdd:PRK11177 549 AEQALAQPTADELMTLVNKF 568
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
417-706 |
2.22e-108 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 331.58 E-value: 2.22e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 417 AMVNKDLALPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQYHQYQAILNSYPNQRVV 496
Cdd:pfam02896 2 AELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDEQFEAYKGVLEAMNGRPVT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 497 MRTLDIGGDKPLPYLPID-EDNPFLGWRGIRFTLDHPDIFLIQLRAMLRASAEsGNLSILLPMVSGIKELDDAITLINQA 575
Cdd:pfam02896 82 VRTLDIGGDKELPYLEEPeEMNPFLGWRGIRIGLDRPELFRTQLRAILRASAF-GNLRIMFPMVASVEELREAKAIIEEV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 576 YSEVVLLDERIQAPKVGVMIEVPSMVYLLPAIAHRVDFVSVGTNDLTQYLLAVDRNNSRVADVYESMHPAVLLALKQIHD 655
Cdd:pfam02896 161 KEELDAEVGFDKDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNERVAYLYDPLHPAVLRLIKEVIR 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 491590344 656 VCLQYQVPVCICGELAGDPFGALLLLGLGYNSLSMNTSNVAKVKYLIRHSQ 706
Cdd:pfam02896 241 AAHRHGKWVGICGEMAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQID 291
|
|
| PtsP |
COG3605 |
Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms]; |
1-182 |
3.48e-61 |
|
Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms];
Pssm-ID: 442824 [Multi-domain] Cd Length: 188 Bit Score: 203.59 E-value: 3.48e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 1 MLSQLREIVEKVSRVDDVHLALDILVKETCAALCTECCTIYLANEEMQRLELMATQGLIFEG-DSIHINFNEGLVGLVKR 79
Cdd:COG3605 2 MLKALRRISEAVASALDLDEALDRIVRRIAEALGVDVCSIYLLDPDGGRLELRATEGLNPEAvGKVRLPLGEGLVGLVAE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 80 SAEPLNLAEASTHPDFKFFPQLGEQVYHSFLGTPIIHRKQVLGVLVIQQKTPRLFSEMEESFLVTLSAQLAVLIAHAQNL 159
Cdd:COG3605 82 RGEPLNLADAASHPRFKYFPETGEEGFRSFLGVPIIRRGRVLGVLVVQSREPREFTEEEVEFLVTLAAQLAEAIANAELL 161
|
170 180
....*....|....*....|....*.
gi 491590344 160 GHWQLASKPTVIKG---LPASTGVAI 182
Cdd:COG3605 162 GELRAALAELSLAReeeREAAVEAAI 187
|
|
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
345-668 |
5.71e-42 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 164.15 E-value: 5.71e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 345 AVVSLEGAANSHAAILSRALGVPAIMGANINTSVVN-----------GKKGIVdgYTGEIYLEpnrqllreyrslvSEES 413
Cdd:PRK06464 407 AIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKdgqevtvscaeGDTGYV--YEGLLEFE-------------VEEV 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 414 ELFAMvnkdlalpAITKddchIEVMLNAGL--SADSNIAInsGVDGVGLYRTE--IAFLLQHH------FPS-EDEQYHQ 482
Cdd:PRK06464 472 SLEEM--------PETP----TKIMMNVGNpeRAFDFAAL--PNDGVGLARLEfiINNMIGVHplalleFDQqDADLKAE 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 483 YQAILNSYPNQR----------------------VVMRTLD---------IGGDKPLPylpiDEDNPFLGWRGIRFTLDH 531
Cdd:PRK06464 538 IEELTAGYASPEefyvdklaegiatvaaafypkpVIVRLSDfksneyanlIGGERYEP----EEENPMLGFRGASRYLSE 613
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 532 P--DIFLIQLRAMLRASAESG--NLSILLPMVSGIKELDDAITLINQaysevVLLDERIQAPKVGVMIEVPSMVYLLPAI 607
Cdd:PRK06464 614 SfrEAFALECEAIKRVREEMGltNVEVMIPFVRTVEEAEKVIELLAE-----NGLKRGENGLKVIMMCEIPSNALLAEEF 688
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 491590344 608 AHRVDFVSVGTNDLTQYLLAVDRNNSRVADVYESMHPAVLLALKQIHDVCLQYQVPVCICG 668
Cdd:PRK06464 689 LEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLFDERNPAVKKLISMAIKAAKKAGKYVGICG 749
|
|
| PEP-utilizers_N |
pfam05524 |
PEP-utilizing enzyme, N-terminal; |
172-294 |
1.97e-27 |
|
PEP-utilizing enzyme, N-terminal;
Pssm-ID: 461671 [Multi-domain] Cd Length: 125 Bit Score: 107.70 E-value: 1.97e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 172 KGLPASTGVAIGE-FWFDNTQPNLNDVFPASALDKEREHELLAVAVERALSDFRRMRKKFDSEINKDALAIFDLFTHLLN 250
Cdd:pfam05524 1 KGIGASPGIAIGKaVVLEEPELEVPDEREVPADDVEAEIARLEAALEAAREELEALAERAAGELGEEEAAIFEAHLMMLE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 491590344 251 DPMLRGDLKKQIEKGDR-ADWALRQVVETYSNRFARMSDVYLRER 294
Cdd:pfam05524 81 DPELLEEVEELIREGGLnAEAAVKEVVDEFAAMFEAMDDPYLRER 125
|
|
| PRK11377 |
PRK11377 |
dihydroxyacetone kinase subunit M; Provisional |
148-393 |
5.63e-26 |
|
dihydroxyacetone kinase subunit M; Provisional
Pssm-ID: 183108 [Multi-domain] Cd Length: 473 Bit Score: 112.15 E-value: 5.63e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 148 QLAvliahAQNLGHwQLASKPTVIKGLPAS-TGVAIgeFWfdntQPNLNDVFPASALDKEREHELLAVAVERALSDFRRM 226
Cdd:PRK11377 233 QLA-----EDNFGE-TEEVAPPTLRPVPSPvSGKAF--YY----QPVLCTVQAKSTLTVEEEQERLRQAIDFTLLDLMTL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 227 RKKFDSEINKDALAIFDLFTHLLNDPMLRGDLKKQIEKGD-RADWALRQVVETYSNRFARMSDVYLRERAQDIRELGQRL 305
Cdd:PRK11377 301 TAKAEASGLDDIAAIFSGHHTLLDDPELLAAASERLQHEHcTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRT 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 306 LYFLHNSEQEHASIDRPVILVANELTATLLASIPKQHLLAVVSLEGAANSHAAILSRALGVPAI--MGANINtSVVNGKK 383
Cdd:PRK11377 381 LVHLTQTKEELPQFNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPLSHSAIIARELGIGWIcqQGEKLY-AIQPEET 459
|
250
....*....|
gi 491590344 384 GIVDGYTGEI 393
Cdd:PRK11377 460 LTLDVKTQRL 469
|
|
| GAF |
smart00065 |
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these ... |
17-157 |
4.45e-18 |
|
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these domains in PDE6B result in autosomal recessive inheritance of retinitis pigmentosa.
Pssm-ID: 214500 [Multi-domain] Cd Length: 149 Bit Score: 81.66 E-value: 4.45e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 17 DVHLALDILVKETCAALCTECCTIYLANE-EMQRLELMATQGLIFEGDSIHINFNEGLVGLVKRSAEPLNLAEASTHPDF 95
Cdd:smart00065 1 DLEELLQTILEELRQLLGADRVLIYLVDEnDRGELVLVAADGLTLPTLGIRFPLDEGLAGRVAETGRPLNIPDVEADPLF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491590344 96 KFFPQLGEQVYHSFLGTPIIHRKQVLGVLVIQQKT-PRLFSEMEESFLVTLSAQLAVLIAHAQ 157
Cdd:smart00065 81 AEDLLGRYQGVRSFLAVPLVADGELVGVLALHNKKsPRPFTEEDEELLQALANQLAIALANAQ 143
|
|
| GAF |
COG2203 |
GAF domain [Signal transduction mechanisms]; |
2-505 |
6.30e-17 |
|
GAF domain [Signal transduction mechanisms];
Pssm-ID: 441805 [Multi-domain] Cd Length: 712 Bit Score: 85.25 E-value: 6.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 2 LSQLREIVEKVSRVDDVHLALDILVKETCAALCTECCTIYLANEEMQRLELMATQGLIFEGdSIHINFNEGLVGLVKRSA 81
Cdd:COG2203 192 LALLNEISQALRSALDLEELLQRILELAGELLGADRGAILLVDEDGGELELVAAPGLPEEE-LGRLPLGEGLAGRALRTG 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 82 EPLNLAEASTHPDFKFFPQ--LGEQVYHSFLGTPIIHRKQVLGVLVIQQKTPRLFSEMEESFLVTLSAQLAVLIAHAQNL 159
Cdd:COG2203 271 EPVVVNDASTDPRFAPSLRelLLALGIRSLLCVPLLVDGRLIGVLALYSKEPRAFTEEDLELLEALADQAAIAIERARLY 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 160 GHWQLASKptvikgLPASTGVAIGEFWFDNTQPNLNDVFPASALDKEREHELLAVAVERALSDFRRMRKKFDSEINKDAL 239
Cdd:COG2203 351 EALEAALA------ALLQELALLRLLLDLELTLLRLRQLLLELLLALLLLLSLLGAELLLLLLDAADLSGLLALEGLLLL 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 240 AIFDLFTHLLNDPMLRGDLKKQIEKGDRADWALRQVVETYSNRFARMSDVYLRERAQDIRELGQRLLYFLHNSEQEHASI 319
Cdd:COG2203 425 DLLLLLLLLRRILLLRVLRRLLLGDEEGLVLLLALAELELLEILELLVLLAVILLALALLAALLLLLLLLLALLALSALA 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 320 DRPVILVANELTATLLASIPKQHLLAVVSLEGAANSHAAILSRALGVPAIMGANINTSVVNGKKGIVDGYTGEIYLEPNR 399
Cdd:COG2203 505 VLASLLLALLLLLLLLLLLLLLGLLAALAADLLLLAAALLEDLLILLLVLLLERELLTLVGVLLLLGLSVLLIELALALI 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 400 QLLREYRSLVSEESELFAMVNKDLALPAITKDDCHIEVMLNAGLSADSNIAINSGVDGVGLYRTEIAFLLQHHFPSEDEQ 479
Cdd:COG2203 585 LALALLELLLVAVGDLLLLERDLLLLLVLLVRLLLELLVVTLELTVLVVLAAVEDSALLLRLALALASLVLLRALLATEL 664
|
490 500
....*....|....*....|....*.
gi 491590344 480 YHQYQAILNSYPNQRVVMRTLDIGGD 505
Cdd:COG2203 665 DLILDSSLLLGLLLLGALLLLGGGLA 690
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
319-391 |
6.86e-17 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 75.52 E-value: 6.86e-17
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491590344 319 IDRPVILVANELTATLLASIPKqhLLAVVSLEGAANSHAAILSRALGVPAIMGA-NINTSVVNGKKGIVDGYTG 391
Cdd:pfam00391 2 LPEGVILVAPDTTPSDTAGLDK--AAGIVTERGGMTSHAAIVARELGIPAVVGVgDATILLKEGDLVTVDGSTG 73
|
|
| GAF |
pfam01590 |
GAF domain; This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl ... |
17-153 |
6.53e-13 |
|
GAF domain; This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54. This domain can bind biliverdine and phycocyanobilin (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 460259 [Multi-domain] Cd Length: 133 Bit Score: 66.35 E-value: 6.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 17 DVHLALDILVKETCAALCTECCTIYLANEEmqrLELMATQGLIFEgDSIHINFNEGLVGLVKRSAEPLNLAEASTHPDFK 96
Cdd:pfam01590 1 DLEEILQTILEELRELLGADRCALYLPDAD---GLEYLPPGARWL-KAAGLEIPPGTGVTVLRTGRPLVVPDAAGDPRFL 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 491590344 97 FFPQLGEQV-YHSFLGTPIIHRKQVLGVLVIQQKTPRlFSEMEESFLVTLSAQLAVLI 153
Cdd:pfam01590 77 DPLLLLRNFgIRSLLAVPIIDDGELLGVLVLHHPRPP-FTEEELELLEVLADQVAIAL 133
|
|
| GAF_2 |
pfam13185 |
GAF domain; The GAF domain is named after some of the proteins it is found in, including ... |
19-154 |
8.00e-12 |
|
GAF domain; The GAF domain is named after some of the proteins it is found in, including cGMP-specific phosphodiesterases, adenylyl cyclases and FhlA. It is also found in guanylyl cyclases and phytochromes. The structure of a GAF domain shows that the domain shares a similar fold with the PAS domain. This domain can bind O2, CO and NO (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 433019 [Multi-domain] Cd Length: 137 Bit Score: 63.25 E-value: 8.00e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 19 HLALDILVKETCAALCT----ECCTIYLANEEmqRLELMATQGLIFEGDSIHINFNEGLVGLVKRSAEPLNLAEASTHPD 94
Cdd:pfam13185 1 AADLEELLDAVLEAAVElgasAVGFILLVDDD--GRLAAWGGAADELSAALDDPPGEGLVGEALRTGRPVIVNDLAADPA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 95 FKFFPqLGEQVYHSFLGTPIIHRKQVLGVLVIQQKTPRLFSEMEESFLVTLSAQLAVLIA 154
Cdd:pfam13185 79 KKGLP-AGHAGLRSFLSVPLVSGGRVVGVLALGSNRPGAFDEEDLELLELLAEQAAIAIE 137
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
315-394 |
8.05e-08 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 55.52 E-value: 8.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 315 EHASIDRPVILVAN----ELTATLLASipkqhlLAVVSLEGAANSHAAILSRALGVPAIM--GANINTSVVnGKKGIVDG 388
Cdd:PRK05878 374 DAADRGEPVILVRDhtrpDDVHGMLAA------QGIVTEVGGATSHAAVVSRELGRVAVVgcGAGVAAALA-GKEITVDG 446
|
....*.
gi 491590344 389 YTGEIY 394
Cdd:PRK05878 447 YEGEVR 452
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
345-393 |
1.21e-06 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 51.75 E-value: 1.21e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 491590344 345 AVVSLEGAANSHAAILSRALGVPAIMGANINTSVVngKKGI---VDGYTGEI 393
Cdd:COG0574 405 GIVTERGGMTSHAAIVARELGIPAVVGCGDATRVL--KDGDeitVDGTTGEV 454
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
324-394 |
1.81e-06 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 50.67 E-value: 1.81e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491590344 324 ILVANELTATLLASIPKqhLLAVVSLEGAANSHAAILSRALGVPAIMGANINTSVV-NGKKGIVDGYTGEIY 394
Cdd:COG3848 245 ILVVPSTDAEFVPAIEK--AAGIITEEGGLTSHAAIVGLELGIPVIVGAEGATEILkDGQVVTVDAERGVVY 314
|
|
| GAF_3 |
pfam13492 |
GAF domain; |
22-155 |
9.40e-06 |
|
GAF domain;
Pssm-ID: 433253 [Multi-domain] Cd Length: 129 Bit Score: 45.82 E-value: 9.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 22 LDILVKETCAALCTECCTIYLANEEMQRLELMATqglIFEGDSIHINFNEG--LVGLVkrsaepLNLAEASTHPDFKFFP 99
Cdd:pfam13492 6 LEALLKLLVRLLGAERAAVYLLDEDGNKLQVAAG---YDGEPDPSESLDADspLARRA------LSSGEPISGLGSAGED 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 491590344 100 QLGEQVYHSflgTPIIHRKQVLGVLVIQQKTPRLFSEMEESFLVTLSAQLAVLIAH 155
Cdd:pfam13492 77 GLPDGPALV---VPLVAGRRVIGVLALASSKPRAFDAEDLRLLESLAAQIATAIEN 129
|
|
| FhlA |
COG3604 |
FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis ... |
109-153 |
4.01e-05 |
|
FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 442823 [Multi-domain] Cd Length: 338 Bit Score: 46.38 E-value: 4.01e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 491590344 109 FLGTPIIHRKQVLGVLVIQQKTPRLFSEMEESFLVTLSAQLAVLI 153
Cdd:COG3604 76 FLGVPLRVGGEVLGVLTLDSRRPGAFSEEDLRLLETLASLAAVAI 120
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
345-393 |
5.75e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 46.57 E-value: 5.75e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 491590344 345 AVVSLEGAANSHAAILSRALGVPAIMGANINTSVV-NGKKGIVDGYTGEI 393
Cdd:PRK08296 550 ATVTDIGGVMSHAAIVCREYGLPAVVGTGNATKRIkTGQRLRVDGTKGVV 599
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
311-394 |
2.35e-04 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 44.53 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491590344 311 NSEQEHASIDRPVILVANELTATLLASIPKQHllAVVSLEGAANSHAAILSRALGVPAIMGANINTSVV-NGKKGIVDGY 389
Cdd:PRK06354 501 KTAAEVAKVNEGDILVTPSTDADMIPAIEKAA--AIITEEGGLTSHAAVVGLRLGIPVIVGVKNATSLIkDGQIITVDAA 578
|
....*
gi 491590344 390 TGEIY 394
Cdd:PRK06354 579 RGVVY 583
|
|
| |
