NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|491592791|ref|WP_005450356|]
View 

MULTISPECIES: TfoX/Sxy family DNA transformation protein [Vibrio]

Protein Classification

TfoX/Sxy family DNA transformation protein( domain architecture ID 10006898)

TfoX/Sxy family DNA transformation protein similar to the N-terminal domains of Escherichia coli competence activator Sxy and Haemophilus influenzae DNA transformation protein TfoX

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TfoX COG3070
Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];
2-112 1.48e-38

Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];


:

Pssm-ID: 442304  Cd Length: 114  Bit Score: 128.48  E-value: 1.48e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491592791   2 DKPILKDSMKLFEALGNIKSRSMFGGFGLFADETMFALVVNNQLHIRADQQTSSDFETQGLKPYVYKKRGFPVVTKYYAI 81
Cdd:COG3070    4 SEELVERVRELLAPLGPVTARRMFGGYGLYVDGKMFALVSDDELYLKADEELREAFEAAGCEPFTYEKRGRPVTLGYYLV 83

                         90       100       110
                 ....*....|....*....|....*....|.
gi 491592791  82 SDDLWDTTDRLIEVAKQSLETAKQEKKQQAS 112
Cdd:COG3070   84 PEELLDDPDELLEWARLALEAALRAKPKKKK 114
TfoX_C pfam04994
TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 117-192 8.68e-35

TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the C-terminal presumed domain of TfoX. The domain is found associated with pfam00383 in Swiss:Q9JZR1. It is also found as an isolated domain in some proteins suggesting this is an autonomous domain.


:

Pssm-ID: 461512 [Multi-domain]  Cd Length: 77  Bit Score: 117.66  E-value: 8.68e-35
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491592791  117 RLKDLPNLRLATERMLKKAGIDSVEQLEAEGALNAYKAIQDTHAStVSLELLWALEGAIKGTHWSVVPQSRREELM 192
Cdd:pfam04994   1 RLKDLPNLGLKLERMLKKAGIKTVADLRELGAVEAYLRLKQSGSS-VSLNLLWALEGALQGVHWNVLPEERKEELL 75
 
Name Accession Description Interval E-value
TfoX COG3070
Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];
2-112 1.48e-38

Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];


Pssm-ID: 442304  Cd Length: 114  Bit Score: 128.48  E-value: 1.48e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491592791   2 DKPILKDSMKLFEALGNIKSRSMFGGFGLFADETMFALVVNNQLHIRADQQTSSDFETQGLKPYVYKKRGFPVVTKYYAI 81
Cdd:COG3070    4 SEELVERVRELLAPLGPVTARRMFGGYGLYVDGKMFALVSDDELYLKADEELREAFEAAGCEPFTYEKRGRPVTLGYYLV 83

                         90       100       110
                 ....*....|....*....|....*....|.
gi 491592791  82 SDDLWDTTDRLIEVAKQSLETAKQEKKQQAS 112
Cdd:COG3070   84 PEELLDDPDELLEWARLALEAALRAKPKKKK 114
TfoX_N pfam04993
TfoX N-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 11-103 5.31e-35

TfoX N-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the N-terminal presumed domain of TfoX. The domain is found as an isolated domain in some proteins suggesting this is an autonomous domain.


Pssm-ID: 428245  Cd Length: 91  Bit Score: 118.45  E-value: 5.31e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491592791   11 KLFEALGNIKSRSMFGGFGLFADETMFALVVNNQLHIRADQQTSSDFETQGLKPYVYKKRGfpVVTKYYAISDDLWDTTD 90
Cdd:pfam04993   1 ELLAPLGPVTSRRMFGGYGLYVDGLMFALVSDGELYLRADEETREEFEAAGCEPFVYAKRG--VTLSYYRVPADALEDPE 78

                          90
                  ....*....|...
gi 491592791   91 RLIEVAKQSLETA 103
Cdd:pfam04993  79 QLARWARLALEAA 91
TfoX_C pfam04994
TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 117-192 8.68e-35

TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the C-terminal presumed domain of TfoX. The domain is found associated with pfam00383 in Swiss:Q9JZR1. It is also found as an isolated domain in some proteins suggesting this is an autonomous domain.


Pssm-ID: 461512 [Multi-domain]  Cd Length: 77  Bit Score: 117.66  E-value: 8.68e-35
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491592791  117 RLKDLPNLRLATERMLKKAGIDSVEQLEAEGALNAYKAIQDTHAStVSLELLWALEGAIKGTHWSVVPQSRREELM 192
Cdd:pfam04994   1 RLKDLPNLGLKLERMLKKAGIKTVADLRELGAVEAYLRLKQSGSS-VSLNLLWALEGALQGVHWNVLPEERKEELL 75
 
Name Accession Description Interval E-value
TfoX COG3070
Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];
2-112 1.48e-38

Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];


Pssm-ID: 442304  Cd Length: 114  Bit Score: 128.48  E-value: 1.48e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491592791   2 DKPILKDSMKLFEALGNIKSRSMFGGFGLFADETMFALVVNNQLHIRADQQTSSDFETQGLKPYVYKKRGFPVVTKYYAI 81
Cdd:COG3070    4 SEELVERVRELLAPLGPVTARRMFGGYGLYVDGKMFALVSDDELYLKADEELREAFEAAGCEPFTYEKRGRPVTLGYYLV 83

                         90       100       110
                 ....*....|....*....|....*....|.
gi 491592791  82 SDDLWDTTDRLIEVAKQSLETAKQEKKQQAS 112
Cdd:COG3070   84 PEELLDDPDELLEWARLALEAALRAKPKKKK 114
TfoX_N pfam04993
TfoX N-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 11-103 5.31e-35

TfoX N-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the N-terminal presumed domain of TfoX. The domain is found as an isolated domain in some proteins suggesting this is an autonomous domain.


Pssm-ID: 428245  Cd Length: 91  Bit Score: 118.45  E-value: 5.31e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491592791   11 KLFEALGNIKSRSMFGGFGLFADETMFALVVNNQLHIRADQQTSSDFETQGLKPYVYKKRGfpVVTKYYAISDDLWDTTD 90
Cdd:pfam04993   1 ELLAPLGPVTSRRMFGGYGLYVDGLMFALVSDGELYLRADEETREEFEAAGCEPFVYAKRG--VTLSYYRVPADALEDPE 78

                          90
                  ....*....|...
gi 491592791   91 RLIEVAKQSLETA 103
Cdd:pfam04993  79 QLARWARLALEAA 91
TfoX_C pfam04994
TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 117-192 8.68e-35

TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the C-terminal presumed domain of TfoX. The domain is found associated with pfam00383 in Swiss:Q9JZR1. It is also found as an isolated domain in some proteins suggesting this is an autonomous domain.


Pssm-ID: 461512 [Multi-domain]  Cd Length: 77  Bit Score: 117.66  E-value: 8.68e-35
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491592791  117 RLKDLPNLRLATERMLKKAGIDSVEQLEAEGALNAYKAIQDTHAStVSLELLWALEGAIKGTHWSVVPQSRREELM 192
Cdd:pfam04994   1 RLKDLPNLGLKLERMLKKAGIKTVADLRELGAVEAYLRLKQSGSS-VSLNLLWALEGALQGVHWNVLPEERKEELL 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH