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Conserved domains on  [gi|491624905|ref|WP_005482445|]
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MULTISPECIES: class II fructose-bisphosphate aldolase [Vibrio]

Protein Classification

class II fructose-bisphosphate aldolase( domain architecture ID 10013149)

class II fructose-1,6-bisphosphate (FBP) aldolase catalyzes the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate

EC:  4.1.2.13
Gene Ontology:  GO:0008270|GO:0004332|GO:0016832

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 10-358 0e+00

fructose-bisphosphate aldolase; Provisional


:

Pssm-ID: 236406  Cd Length: 350  Bit Score: 735.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  10 PGVISGDDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLEGQEAQILGAVAG 89
Cdd:PRK09197   1 PGVATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  90 AKYVHAVAEAYGVPVILHTDHAAKKLLPWIDGLLDAGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNM 169
Cdd:PRK09197  81 AKHVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 170 TLEIELGCTGGEEDGVDNSDMDASELYTSPEDVAYAYEKLNAISHRFTIAASFGNVHGVYKPGNVVLTPTILRDSQAYVS 249
Cdd:PRK09197 161 TLEIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKISGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 250 EKFGLPANSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDYLQGQIGNPTGEDAPNKKYYD 329
Cdd:PRK09197 241 KKFGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYD 320

                        330       340
                 ....*....|....*....|....*....
gi 491624905 330 PRVWLRAGQASMVTRLEQAFADLNAIDVL 358
Cdd:PRK09197 321 PRVWLRAAEASMAARLEEAFEDLNSIGVL 349
 
Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 10-358 0e+00

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 735.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  10 PGVISGDDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLEGQEAQILGAVAG 89
Cdd:PRK09197   1 PGVATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  90 AKYVHAVAEAYGVPVILHTDHAAKKLLPWIDGLLDAGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNM 169
Cdd:PRK09197  81 AKHVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 170 TLEIELGCTGGEEDGVDNSDMDASELYTSPEDVAYAYEKLNAISHRFTIAASFGNVHGVYKPGNVVLTPTILRDSQAYVS 249
Cdd:PRK09197 161 TLEIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKISGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 250 EKFGLPANSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDYLQGQIGNPTGEDAPNKKYYD 329
Cdd:PRK09197 241 KKFGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYD 320

                        330       340
                 ....*....|....*....|....*....
gi 491624905 330 PRVWLRAGQASMVTRLEQAFADLNAIDVL 358
Cdd:PRK09197 321 PRVWLRAAEASMAARLEEAFEDLNSIGVL 349
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 15-358 0e+00

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 641.73  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  15 GDDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLEGQEAQILGAVAGAKYVH 94
Cdd:cd00946    1 GDDVLKLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGKGLKNEKQKASIAGAIAAAHHVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  95 AVAEAYGVPVILHTDHAAKKLLPWIDGLLDAGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIE 174
Cdd:cd00946   81 SMAEHYGVPVVLHTDHCAKKLLPWFDGLLEADEEYFKQHGEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 175 LGCTGGEEDGVDNSDMDASELYTSPEDVAYAYEKLNAISHRFTIAASFGNVHGVYKPGNVVLTPTILRDSQAYVSEKFGL 254
Cdd:cd00946  161 IGITGGEEDGVDNSGVDNAELYTQPEDVWYVYEALSKISPNFSIAAAFGNVHGVYKPGNVKLQPEILGEHQDYVREKLGL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 255 -PANSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDYLQGQIGNPTGEDAPNKKYYDPRVW 333
Cdd:cd00946  241 aDDKPLYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDYLQGQIGNPEGPDKPNKKYYDPRVW 320

                        330       340
                 ....*....|....*....|....*
gi 491624905 334 LRAGQASMVTRLEQAFADLNAIDVL 358
Cdd:cd00946  321 LREGEKSMVARVKKAFEDLNSVNKL 345
FruBisAldo_II_A TIGR01520
fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are ...
 4-358 0e+00

fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). This model represents one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterized proteins. This family is well-conserved and includes characterized FBA from Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutamicum. Proteins outside the scope of this model may also be designated as class II fructose-bisphosphate aldolases, but are well separated in an alignment-based phylogenetic tree. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130583  Cd Length: 357  Bit Score: 612.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905    4 IFDFVKPGVISGDDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLEGQEAQ- 82
Cdd:TIGR01520   1 IFDFVKPGVITGDDVHKLFQYAKENNFAIPAINCTSSSTINAALEAAADVKSPIIIQFSNGGAAFIAGKGVKDEVPQGAs 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   83 ILGAVAGAKYVHAVAEAYGVPVILHTDHAAKKLLPWIDGLLDAGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLE 162
Cdd:TIGR01520  81 ILGAIAGAHHVHSIAEHYGVPVVLHTDHCAKKLLPWVDGLLEAGEKYFSAHGKPLFSSHMIDLSEEPIEENIEICVKYLK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  163 RMAKMNMTLEIELGCTGGEEDGVDNSDMDASELYTSPEDVAYAYEKLNAISHRFTIAASFGNVHGVYKPGNVVLTPTILR 242
Cdd:TIGR01520 161 RMAKIKMWLEIEIGITGGEEDGVDNSHMDAEALYTQPEDVYYAYEELSKISPNFSIAAAFGNVHGVYKPGNVKLTPDILA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  243 DSQAYVSEKFGLP-ANSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDYLQGQIGNPTGED 321
Cdd:TIGR01520 241 DGQEYVSEKLGLPaAKPLFFVFHGGSGSTKQEIKEALSYGVVKMNIDTDTQWAYWEGILNYYKNNEDYLQGQLGNPKGPD 320

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 491624905  322 APNKKYYDPRVWLRAGQASMVTRLEQAFADLNAIDVL 358
Cdd:TIGR01520 321 KPNKKFYDPRVWLREGEKSMKARVEKACQELNNINVL 357
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 17-356 1.57e-120

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 349.00  E-value: 1.57e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  17 DVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFagkglklegqeaqilGAVAGAKYVHAV 96
Cdd:COG0191    4 SLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYA---------------GLEYLAAMVRAA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  97 AEAYGVPVILHTDHAAkkllpwidglldaGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELG 176
Cdd:COG0191   69 AEEASVPVALHLDHGA-------------SFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELG 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 177 CTGGEEDGVDNSDMDAseLYTSPEDVAYAYEKlnaiSHRFTIAASFGNVHGVYKpGNVVLTPTILRDSQAYVsekfglpa 256
Cdd:COG0191  136 VVGGEEDGVDVDDAEA--LYTDPEEAAEFVEE----TGVDALAVAIGTVHGVYK-GEPKLDFDRLKEIREAV-------- 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 257 nSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENhdylqgqignptgedaPNKkyYDPRVWLRA 336
Cdd:COG0191  201 -PVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYLAEN----------------PDK--YDPRKYLKP 261

                        330       340
                 ....*....|....*....|
gi 491624905 337 GQASMVTRLEQAFADLNAID 356
Cdd:COG0191  262 AREAMKEVVKEKIRLFGSAG 281
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
16-356 1.11e-117

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 341.70  E-value: 1.11e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   16 DDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGkglklegqeaqilGAVAGAKYVHA 95
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAG-------------GAEALAALVRA 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   96 VAEAYGVPVILHTDHAAKkllpwIDGLLDAGEEyfaqtgkpLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIEL 175
Cdd:pfam01116  68 AAEAAGVPVALHLDHGAS-----FELIKEAIEA--------GFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAEL 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  176 GCTGGEEDGVdnsdMDASELYTSPEDVAYAYEKLNaishRFTIAASFGNVHGVYKPGNvVLTPTILRDSQAYVsekfglp 255
Cdd:pfam01116 135 GRIGGEEDGV----VVDEKLYTDPEEAAEFVEATG----VDALAVAIGNVHGVYKPGP-KLDFDRLKEIQEAV------- 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  256 anSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEnhdylqgqignptgedapnkkyYDPRVWLR 335
Cdd:pfam01116 199 --PVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREYPPN----------------------KDPRKYLR 254

                         330       340
                  ....*....|....*....|.
gi 491624905  336 AGQASMVTRLEQAFADLNAID 356
Cdd:pfam01116 255 PAEEAMKEVVKEKIRLFGSAG 275
 
Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 10-358 0e+00

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 735.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  10 PGVISGDDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLEGQEAQILGAVAG 89
Cdd:PRK09197   1 PGVATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  90 AKYVHAVAEAYGVPVILHTDHAAKKLLPWIDGLLDAGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNM 169
Cdd:PRK09197  81 AKHVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 170 TLEIELGCTGGEEDGVDNSDMDASELYTSPEDVAYAYEKLNAISHRFTIAASFGNVHGVYKPGNVVLTPTILRDSQAYVS 249
Cdd:PRK09197 161 TLEIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKISGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 250 EKFGLPANSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDYLQGQIGNPTGEDAPNKKYYD 329
Cdd:PRK09197 241 KKFGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYD 320

                        330       340
                 ....*....|....*....|....*....
gi 491624905 330 PRVWLRAGQASMVTRLEQAFADLNAIDVL 358
Cdd:PRK09197 321 PRVWLRAAEASMAARLEEAFEDLNSIGVL 349
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 15-358 0e+00

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 641.73  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  15 GDDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLEGQEAQILGAVAGAKYVH 94
Cdd:cd00946    1 GDDVLKLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGKGLKNEKQKASIAGAIAAAHHVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  95 AVAEAYGVPVILHTDHAAKKLLPWIDGLLDAGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIE 174
Cdd:cd00946   81 SMAEHYGVPVVLHTDHCAKKLLPWFDGLLEADEEYFKQHGEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 175 LGCTGGEEDGVDNSDMDASELYTSPEDVAYAYEKLNAISHRFTIAASFGNVHGVYKPGNVVLTPTILRDSQAYVSEKFGL 254
Cdd:cd00946  161 IGITGGEEDGVDNSGVDNAELYTQPEDVWYVYEALSKISPNFSIAAAFGNVHGVYKPGNVKLQPEILGEHQDYVREKLGL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 255 -PANSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDYLQGQIGNPTGEDAPNKKYYDPRVW 333
Cdd:cd00946  241 aDDKPLYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDYLQGQIGNPEGPDKPNKKYYDPRVW 320

                        330       340
                 ....*....|....*....|....*
gi 491624905 334 LRAGQASMVTRLEQAFADLNAIDVL 358
Cdd:cd00946  321 LREGEKSMVARVKKAFEDLNSVNKL 345
FruBisAldo_II_A TIGR01520
fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are ...
 4-358 0e+00

fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). This model represents one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterized proteins. This family is well-conserved and includes characterized FBA from Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutamicum. Proteins outside the scope of this model may also be designated as class II fructose-bisphosphate aldolases, but are well separated in an alignment-based phylogenetic tree. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130583  Cd Length: 357  Bit Score: 612.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905    4 IFDFVKPGVISGDDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLEGQEAQ- 82
Cdd:TIGR01520   1 IFDFVKPGVITGDDVHKLFQYAKENNFAIPAINCTSSSTINAALEAAADVKSPIIIQFSNGGAAFIAGKGVKDEVPQGAs 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   83 ILGAVAGAKYVHAVAEAYGVPVILHTDHAAKKLLPWIDGLLDAGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLE 162
Cdd:TIGR01520  81 ILGAIAGAHHVHSIAEHYGVPVVLHTDHCAKKLLPWVDGLLEAGEKYFSAHGKPLFSSHMIDLSEEPIEENIEICVKYLK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  163 RMAKMNMTLEIELGCTGGEEDGVDNSDMDASELYTSPEDVAYAYEKLNAISHRFTIAASFGNVHGVYKPGNVVLTPTILR 242
Cdd:TIGR01520 161 RMAKIKMWLEIEIGITGGEEDGVDNSHMDAEALYTQPEDVYYAYEELSKISPNFSIAAAFGNVHGVYKPGNVKLTPDILA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  243 DSQAYVSEKFGLP-ANSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDYLQGQIGNPTGED 321
Cdd:TIGR01520 241 DGQEYVSEKLGLPaAKPLFFVFHGGSGSTKQEIKEALSYGVVKMNIDTDTQWAYWEGILNYYKNNEDYLQGQLGNPKGPD 320

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 491624905  322 APNKKYYDPRVWLRAGQASMVTRLEQAFADLNAIDVL 358
Cdd:TIGR01520 321 KPNKKFYDPRVWLREGEKSMKARVEKACQELNNINVL 357
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 18-356 4.31e-179

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 500.10  E-value: 4.31e-179
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  18 VQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLE-GQEAQILGAVAGAKYVHAV 96
Cdd:cd00453    1 VQKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDvPQGAAILGAISGAHHVHQM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  97 AEAYGVPVILHTDHAAKKLLPWIDGLLDAGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELG 176
Cdd:cd00453   81 AEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 177 CTGGEEDGVDNSDMDASELYTSPEDVAYAYEKLNAISHRFTIAASFGNVHGVYKPGNVVLTPTILRDSQAYVSEKFGLPA 256
Cdd:cd00453  161 CTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFTIAASFGNVHGVYKKGNVVLTPTILRDSQEYVSKKHNLPH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 257 NSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDYLQGQIGNPTGEDAPNKKYYDPRVWLRA 336
Cdd:cd00453  241 NSLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVWLRA 320

                        330       340
                 ....*....|....*....|
gi 491624905 337 GQASMVTRLEQAFADLNAID 356
Cdd:cd00453  321 GQTSMIARLEKAFQELNAID 340
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 13-358 5.09e-135

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 386.29  E-value: 5.09e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   13 ISGDDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGkglklegqeaqiLGAVAGAKY 92
Cdd:TIGR00167   1 MMLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAG------------LGAISAMVK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   93 VHAVAEAYGVPVILHTDHAAkkllpwidglldaGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLE 172
Cdd:TIGR00167  69 AMSEAYPYGVPVALHLDHGA-------------SEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVE 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  173 IELGCTGGEEDGVdnSDMDASELYTSPEdvayAYEKLNAISHRFTIAASFGNVHGVYKPGNVVLTPTILRDSQAYVsekf 252
Cdd:TIGR00167 136 AELGTLGGEEDGV--SVADESALYTDPE----EAKEFVKLTGVDSLAAAIGNVHGVYKGEPKGLDFERLEEIQKYV---- 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  253 glpanSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEnhdylqgqignptgedapNKKYYDPRV 332
Cdd:TIGR00167 206 -----NLPLVLHGGSGIPDEEIKKAISLGVVKVNIDTELQIAFAAAVRNYYAE------------------NKDYYDPRV 262

                         330       340
                  ....*....|....*....|....*.
gi 491624905  333 WLRAGQASMVTRLEQAFADLNAIDVL 358
Cdd:TIGR00167 263 WLRPGEKAMKEVVLEKIKLFGSANKA 288
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 17-356 1.57e-120

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 349.00  E-value: 1.57e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  17 DVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFagkglklegqeaqilGAVAGAKYVHAV 96
Cdd:COG0191    4 SLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYA---------------GLEYLAAMVRAA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  97 AEAYGVPVILHTDHAAkkllpwidglldaGEEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELG 176
Cdd:COG0191   69 AEEASVPVALHLDHGA-------------SFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELG 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 177 CTGGEEDGVDNSDMDAseLYTSPEDVAYAYEKlnaiSHRFTIAASFGNVHGVYKpGNVVLTPTILRDSQAYVsekfglpa 256
Cdd:COG0191  136 VVGGEEDGVDVDDAEA--LYTDPEEAAEFVEE----TGVDALAVAIGTVHGVYK-GEPKLDFDRLKEIREAV-------- 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 257 nSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENhdylqgqignptgedaPNKkyYDPRVWLRA 336
Cdd:COG0191  201 -PVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYLAEN----------------PDK--YDPRKYLKP 261

                        330       340
                 ....*....|....*....|
gi 491624905 337 GQASMVTRLEQAFADLNAID 356
Cdd:COG0191  262 AREAMKEVVKEKIRLFGSAG 281
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
16-356 1.11e-117

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 341.70  E-value: 1.11e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   16 DDVQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGkglklegqeaqilGAVAGAKYVHA 95
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAG-------------GAEALAALVRA 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   96 VAEAYGVPVILHTDHAAKkllpwIDGLLDAGEEyfaqtgkpLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIEL 175
Cdd:pfam01116  68 AAEAAGVPVALHLDHGAS-----FELIKEAIEA--------GFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAEL 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  176 GCTGGEEDGVdnsdMDASELYTSPEDVAYAYEKLNaishRFTIAASFGNVHGVYKPGNvVLTPTILRDSQAYVsekfglp 255
Cdd:pfam01116 135 GRIGGEEDGV----VVDEKLYTDPEEAAEFVEATG----VDALAVAIGNVHGVYKPGP-KLDFDRLKEIQEAV------- 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  256 anSLNFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEnhdylqgqignptgedapnkkyYDPRVWLR 335
Cdd:pfam01116 199 --PVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREYPPN----------------------KDPRKYLR 254

                         330       340
                  ....*....|....*....|.
gi 491624905  336 AGQASMVTRLEQAFADLNAID 356
Cdd:pfam01116 255 PAEEAMKEVVKEKIRLFGSAG 275
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 21-341 1.08e-51

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 173.10  E-value: 1.08e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  21 VFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLklegqeaqilgavagAKYVHAVAEAY 100
Cdd:cd00947    4 LLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAGLELL---------------VAMVKAAAERA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 101 GVPVILHTDHAAKkllpwIDGLLDAgeeyfAQTGkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCTGG 180
Cdd:cd00947   69 SVPVALHLDHGSS-----FELIKRA-----IRAG---FSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGG 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 181 EEDGVDNSDMdaseLYTSPEDVAyayeklnaishRF-------TIAASFGNVHGVYKPGnvvlTPTILRDSQAYVSEKFG 253
Cdd:cd00947  136 EEDGVVGDEG----LLTDPEEAE-----------EFveetgvdALAVAIGTSHGAYKGG----EPKLDFDRLKEIAERVN 196

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 254 LPanslnFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEnhdylqgqignptgedapNKKYYDPRVW 333
Cdd:cd00947  197 VP-----LVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALREYLAE------------------NPKEFDPRKY 253


                 ....*...
gi 491624905 334 LRAGQASM 341
Cdd:cd00947  254 LAPAIEAV 261
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 20-342 1.83e-41

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 146.35  E-value: 1.83e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   20 KVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGaaffagkgLKLEGQEAQILGAVAGAkyvhavAEA 99
Cdd:TIGR01859   6 EILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGA--------IKYMGGYKMAVAMVKTL------IER 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  100 YG-VPVILHTDHAAKkllpwIDGLLDAgeeyfAQTGkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCT 178
Cdd:TIGR01859  72 MSiVPVALHLDHGSS-----YESCIKA-----IKAG---FSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTL 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  179 GGEEDGVDNSDMDaselYTSPEDvAYAYEKLNAISHrftIAASFGNVHGVYKPgnvvlTPTILRDSQAYVSEKFGLPans 258
Cdd:TIGR01859 139 GGIEDGVDEKEAE----LADPDE-AEQFVKETGVDY---LAAAIGTSHGKYKG-----EPGLDFERLKEIKELTNIP--- 202

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  259 lnFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEnhdylqgqignptgedapNKKYYDPRVWLRAGQ 338
Cdd:TIGR01859 203 --LVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAFTAAIRKVLTE------------------KKDEYDPRKILGPAR 262


                  ....
gi 491624905  339 ASMV 342
Cdd:TIGR01859 263 EAIK 266
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
18-308 9.75e-36

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 131.39  E-value: 9.75e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  18 VQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFfagkglklegqeaqilgavAGAKYVHAV- 96
Cdd:PRK12857   6 VAELLKKAEKGGYAVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKY-------------------AGIEYISAMv 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  97 ---AEAYGVPVILHTDHAAKkllpwidglldageeyFAQTGKPL---FSSHMIDLSEESLEENIEISAKYLERMAKMNMT 170
Cdd:PRK12857  67 rtaAEKASVPVALHLDHGTD----------------FEQVMKCIrngFTSVMIDGSKLPLEENIALTKKVVEIAHAVGVS 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 171 LEIELGCTGGEEDGVDNSDMDAseLYTSPEDVAYAYEKLNAIShrftIAASFGNVHGVYKpgnvvLTPTILRDSQAYVSE 250
Cdd:PRK12857 131 VEAELGKIGGTEDDITVDEREA--AMTDPEEARRFVEETGVDA----LAIAIGTAHGPYK-----GEPKLDFDRLAKIKE 199

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 491624905 251 KFGLPanslnFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHD 308
Cdd:PRK12857 200 LVNIP-----IVLHGSSGVPDEAIRKAISLGVRKVNIDTNIREAFVARLREVLEKNPD 252
PRK08185 PRK08185
hypothetical protein; Provisional
 23-314 2.84e-32

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 122.14  E-value: 2.84e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  23 EVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNG-----GAAFFAgkglklegqeaqilgavagakYVHAVA 97
Cdd:PRK08185   6 KVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNeldflGDNFFA---------------------YVRERA 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  98 EAYGVPVILHTDHAAKkllpwIDGLLDAgeeyfAQTGkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGC 177
Cdd:PRK08185  65 KRSPVPFVIHLDHGAT-----IEDVMRA-----IRCG---FTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELGT 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 178 TGGE----EDGVDNSdmdaseLYTSPEDvAYAYEKLNAIShrfTIAASFGNVHGVYKPGnvvLTPTILRDSQAYVSEKFG 253
Cdd:PRK08185 132 IGNTgtsiEGGVSEI------IYTDPEQ-AEDFVSRTGVD---TLAVAIGTAHGIYPKD---KKPELQMDLLKEINERVD 198

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491624905 254 LPanslnFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEN-HDYLQGQI 314
Cdd:PRK08185 199 IP-----LVLHGGSANPDAEIAESVQLGVGKINISSDMKYAFFKKVREILSDNpSLYEPNQI 255
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 25-341 1.60e-31

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 120.23  E-value: 1.60e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  25 AKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFfAGKGlklegqeaQILGAVAGAkyvhavAEAYGVPV 104
Cdd:PRK09195  13 AQRGGYAVPAFNIHNLETMQVVVETAAELHSPVIIAGTPGTFSY-AGTE--------YLLAIVSAA------AKQYHHPL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 105 ILHTDHAAKklLPWIDGLLDAGeeyfaqtgkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCTGGEEDG 184
Cdd:PRK09195  78 ALHLDHHEK--FDDIAQKVRSG-----------VRSVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLGGQEDD 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 185 VDNSDMDAseLYTSPEDVAYAYEKLNAIShrftIAASFGNVHGVYKPgnvvlTPTILRDSQAYVSEKFGLPanslnFVFH 264
Cdd:PRK09195 145 LQVDEADA--LYTDPAQAREFVEATGIDS----LAVAIGTAHGMYKG-----EPKLDFDRLENIRQWVNIP-----LVLH 208

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491624905 265 GGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDYLqgqignptgedapnkkyyDPRVWLRAGQASM 341
Cdd:PRK09195 209 GASGLPTKDIQQTIKLGICKVNVATELKIAFSQALKNYLTEHPEAN------------------DPRHYLQPAKSAM 267
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
25-341 1.07e-30

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 117.87  E-value: 1.07e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  25 AKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFfagkglklegqeaqilgavAGAKYVHAVAEA----Y 100
Cdd:PRK12737  13 AQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSY-------------------AGTDYIVAIAEVaarkY 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 101 GVPVILHTDHAAKklLPWIDGLLDAGeeyfaqtgkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCTGG 180
Cdd:PRK12737  74 NIPLALHLDHHED--LDDIKKKVRAG-----------IRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGG 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 181 EEDGVDNSDMDAseLYTSPEDVAYAYEKLNAIShrftIAASFGNVHGVYKPgnvvlTPTILRDSQAYVSEKFGLPansln 260
Cdd:PRK12737 141 QEDDLVVDEKDA--MYTNPDAAAEFVERTGIDS----LAVAIGTAHGLYKG-----EPKLDFERLAEIREKVSIP----- 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 261 FVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDylqgqiGNptgedapnkkyyDPRVWLRAGQAS 340
Cdd:PRK12737 205 LVLHGASGVPDEDVKKAISLGICKVNVATELKIAFSDAVKKYFYENPK------AN------------DPRKYMTPGKAA 266


                 .
gi 491624905 341 M 341
Cdd:PRK12737 267 M 267
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 25-334 1.48e-29

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 115.08  E-value: 1.48e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  25 AKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGkglklegqeaqilgAVAGAKYVHAVAEAYG--V 102
Cdd:PRK08610  13 AKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSG--------------FYTVVKMVEGLMHDLNitI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 103 PVILHTDHAAKklLPWIDGLLDAGeeyfaqtgkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCTGGEE 182
Cdd:PRK08610  79 PVAIHLDHGSS--FEKCKEAIDAG-----------FTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQE 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 183 DGVdnsdMDASELYTSPEDVAYAYEKlNAIShrfTIAASFGNVHGVYKPgnvvlTPTILRDSQAYVSEKFGLPanslnFV 262
Cdd:PRK08610 146 DDV----VADGIIYADPKECQELVEK-TGID---ALAPALGSVHGPYKG-----EPKLGFKEMEEIGLSTGLP-----LV 207

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491624905 263 FHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRqyEAENHDylqgqignptgedapnKKYYDPRVWL 334
Cdd:PRK08610 208 LHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAVR--DVLNND----------------KEVYDPRKYL 261
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
25-347 3.05e-25

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 104.27  E-value: 3.05e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  25 AKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSnGGAAFFAGkglklegqeAQILgavagAKYVHAVAEAY-GVP 103
Cdd:PRK09196  13 AAEHGYGVPAFNVNNLEQVQAIMEAADETDSPVILQAS-AGARKYAG---------EPFL-----RHLILAAVEEYpHIP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 104 VILHTDHAAkkllpwidgllDAGEEYFA-QTGkplFSSHMIDLSEE-------SLEENIEISAKYLERMAKMNMTLEIEL 175
Cdd:PRK09196  78 VVMHQDHGN-----------SPATCQRAiQLG---FTSVMMDGSLKadgktpaSYEYNVDVTRKVVEMAHACGVSVEGEL 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 176 GC-------TGGEEDGVD-NSDMDASELYTSPEDVA--YAYEKLNAIshrftiAASFGNVHGVYK----PGNVVLTPTIL 241
Cdd:PRK09196 144 GClgsletgMGGEEDGHGaEGKLSHDQLLTDPEEAAdfVKKTQVDAL------AIAIGTSHGAYKftrkPTGDVLAIDRI 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 242 RDSQAYvsekfgLPANSLnfVFHGGS---------------------GSSLEEIRESIGYGVIKMNIDTDTQWATWDGIR 300
Cdd:PRK09196 218 KEIHAR------LPNTHL--VMHGSSsvpqelldiineyggdmpetyGVPVEEIQEGIKHGVRKVNIDTDLRLAMTGAIR 289

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 491624905 301 QYEAEnhdylqgqignptgedapNKKYYDPRVWLRAGQASM----VTRLEQ 347
Cdd:PRK09196 290 RFLAE------------------NPSEFDPRKYLKPAMEAMkkicKARYEA 322
gatY PRK07998
class II aldolase;
25-308 8.53e-25

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 101.76  E-value: 8.53e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  25 AKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFsnggaaffAGKGLKLEGQEaqILgavagAKYVHAVAEAYGVPV 104
Cdd:PRK07998  13 IQEKHVLAGAFNTTNLETTISILNAIERSGLPNFIQI--------APTNAQLSGYD--YI-----YEIVKRHADKMDVPV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 105 ILHTDHAakKLLPWIDGLLDAGeeyfaqtgkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCTGGEEDG 184
Cdd:PRK07998  78 SLHLDHG--KTFEDVKQAVRAG-----------FTSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAILGKEDD 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 185 vDNSDMDAselYTSPEDVAYAYEKLNAIshrfTIAASFGNVHGVYkpgnvvLTPTILRDSQAYVSEKFGLPanslnFVFH 264
Cdd:PRK07998 145 -HVSEADC---KTEPEKVKDFVERTGCD----MLAVSIGNVHGLE------DIPRIDIPLLKRIAEVSPVP-----LVIH 205

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 491624905 265 GGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHD 308
Cdd:PRK07998 206 GGSGIPPEILRSFVNYKVAKVNIASDLRKAFITTVGKAYVNNHN 249
PRK06806 PRK06806
class II aldolase;
25-309 5.07e-24

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 99.83  E-value: 5.07e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  25 AKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNggaaffagkgLKLEGQEAQILGAVagakyVHAVAEAYGVPV 104
Cdd:PRK06806  13 ANQENYGVGAFSVANMEMVMGAIKAAEELNSPIILQIAE----------VRLNHSPLHLIGPL-----MVAAAKQAKVPV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 105 ILHTDHAakKLLPWIDGLLDAGeeyfaqtgkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCTGGEEDG 184
Cdd:PRK06806  78 AVHFDHG--MTFEKIKEALEIG-----------FTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDG 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 185 VDNSDMdaseLYTSPEDVAYAYEKLNAIShrftIAASFGNVHGVYKPgnvvlTPTILRDSQAYVSEKFGLPanslnFVFH 264
Cdd:PRK06806 145 SEDIEM----LLTSTTEAKRFAEETDVDA----LAVAIGNAHGMYNG-----DPNLRFDRLQEINDVVHIP-----LVLH 206

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 491624905 265 GGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQY--EAENHDY 309
Cdd:PRK06806 207 GGSGISPEDFKKCIQHGIRKINVATATFNSVITAVNNLvlNTPYSDY 253
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
19-341 2.80e-23

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 98.64  E-value: 2.80e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  19 QKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLEGQeaqilGAVAGAKYVhavae 98
Cdd:PRK07084  13 REMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVSKGARKYANATLLRYMAQ-----GAVEYAKEL----- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  99 AYGVPVILHTDHAAKKLLpwIDGLLDAGeeyfaqtgkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCT 178
Cdd:PRK07084  83 GCPIPIVLHLDHGDSFEL--CKDCIDSG-----------FSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVL 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 179 GGEEDGVdnsdMDASELYTSPEDVAYAYEKLNAIShrftIAASFGNVHGVYK--PGNVVltPTILRDSQAYVSEKF-GLP 255
Cdd:PRK07084 150 AGVEDEV----SAEHHTYTQPEEVEDFVKKTGVDS----LAISIGTSHGAYKfkPGQCP--PPLRFDILEEIEKRIpGFP 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 256 anslnFVFHGGS---------------------GSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEnhdylqgqi 314
Cdd:PRK07084 220 -----IVLHGSSsvpqeyvktineyggklkdaiGIPEEQLRKAAKSAVCKINIDSDGRLAMTAAIRKVFDE--------- 285

                        330       340
                 ....*....|....*....|....*..
gi 491624905 315 gnptgedapNKKYYDPRVWLRAGQASM 341
Cdd:PRK07084 286 ---------KPEEFDPRKYLGPARDEL 303
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 18-341 6.86e-23

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 96.66  E-value: 6.86e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  18 VQKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKglklegqeAQILGAVAGAKYVHAVA 97
Cdd:PRK07709   6 MKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGF--------KTVVAMVKALIEEMNIT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  98 eaygVPVILHTDHAAKklLPWIDGLLDAGeeyfaqtgkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGC 177
Cdd:PRK07709  78 ----VPVAIHLDHGSS--FEKCKEAIDAG-----------FTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGT 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 178 TGGEEDGVDNSDMdaseLYTSPEDVayayEKLNAISHRFTIAASFGNVHGVYKPgnvvlTPTILRDSQAYVSEKFGLPan 257
Cdd:PRK07709 141 VGGQEDDVIAEGV----IYADPAEC----KHLVEATGIDCLAPALGSVHGPYKG-----EPNLGFAEMEQVRDFTGVP-- 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 258 slnFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEnhdylqgqignptgedapNKKYYDPRVWLRAG 337
Cdd:PRK07709 206 ---LVLHGGTGIPTADIEKAISLGTSKINVNTENQIEFTKAVREVLNK------------------DQEVYDPRKFIGPG 264


                 ....
gi 491624905 338 QASM 341
Cdd:PRK07709 265 RDAI 268
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
25-341 1.37e-22

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 95.87  E-value: 1.37e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  25 AKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGgaaffAGKGLKLEGQEAqilgavagakYVHAVAEAYGVPV 104
Cdd:PRK12738  13 AQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPG-----TFKHIALEEIYA----------LCSAYSTTYNMPL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 105 ILHTDHaaKKLLPWIDGLLDAGeeyfaqtgkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCTGGEEDg 184
Cdd:PRK12738  78 ALHLDH--HESLDDIRRKVHAG-----------VRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVED- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 185 vdNSDMDA-SELYTSPEDvAYAYEKLNAIShrfTIAASFGNVHGVYKPgnvvlTPTILRDSQAYVSEKFGLPanslnFVF 263
Cdd:PRK12738 144 --DMSVDAeSAFLTDPQE-AKRFVELTGVD---SLAVAIGTAHGLYSK-----TPKIDFQRLAEIREVVDVP-----LVL 207

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491624905 264 HGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAENHDylqgqiGNptgedapnkkyyDPRVWLRAGQASM 341
Cdd:PRK12738 208 HGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQ------GN------------DPRYYMRVGMDAM 267
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 19-347 1.18e-21

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 93.41  E-value: 1.18e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  19 QKVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLklegqeAQILgavagakyVHAVAE 98
Cdd:PRK07315   7 EKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKV------CKNL--------IENLVE 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  99 AYG--VPVILHTDHaakkllpwidGLLDAGEEYFaQTGkplFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELG 176
Cdd:PRK07315  73 SMGitVPVAIHLDH----------GHYEDALECI-EVG---YTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVG 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 177 CTGGEEDGVdnsdMDASELYTSPEDVAYAYEKLNaishrfTIAASFGNVHGVYKPGNVVLTPTILRDSQAYVSekfGLPa 256
Cdd:PRK07315 139 TIGGEEDGI----IGKGELAPIEDAKAMVETGID------FLAAGIGNIHGPYPENWEGLDLDHLEKLTEAVP---GFP- 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 257 nslnFVFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEnhdylqgqiGNPTGEDAPNKKYYDPRVWLRA 336
Cdd:PRK07315 205 ----IVLHGGSGIPDDQIQEAIKLGVAKVNVNTECQIAFANATRKFARD---------YEANEAEYDKKKLFDPRKFLAP 271

                        330
                 ....*....|.
gi 491624905 337 GQASMVTRLEQ 347
Cdd:PRK07315 272 GVKAIQASVEE 282
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
23-301 9.45e-21

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 90.58  E-value: 9.45e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  23 EVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFsnggaAFFAGKGLKLEgqeaqilgavAGAKYVHAVAEAYGV 102
Cdd:PRK06801  11 AHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINI-----AEVHFKYISLE----------SLVEAVKFEAARHDI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 103 PVILHTDHaakkllpwidGL-LDAgeeyFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCTGGE 181
Cdd:PRK06801  76 PVVLNLDH----------GLhFEA----VVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGD 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 182 EDGVDNSDMDASeLYTSPEdVAYAYEKLNAIShrfTIAASFGNVHGVYKPgnvvlTPTILRDSQAYVSEKFGLPanslnF 261
Cdd:PRK06801 142 EGGALYGEADSA-KFTDPQ-LARDFVDRTGID---ALAVAIGNAHGKYKG-----EPKLDFARLAAIHQQTGLP-----L 206

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 491624905 262 VFHGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQ 301
Cdd:PRK06801 207 VLHGGSGISDADFRRAIELGIHKINFYTGMSQAALAAVEQ 246
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
25-349 3.27e-19

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 87.53  E-value: 3.27e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  25 AKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKlegqeaqilgavagaKYVHAVAEAY-GVP 103
Cdd:PRK13399  13 AAENGYGVPAFNVNNMEQILAIMEAAEATDSPVILQASRGARKYAGDAMLR---------------HMVLAAAEMYpDIP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 104 VILHTDHAakkllpwidglldAGEEYFAQTGKPLFSSHMIDLSEE-------SLEENIEISAKYLERMAKMNMTLEIELG 176
Cdd:PRK13399  78 ICLHQDHG-------------NSPATCQSAIRSGFTSVMMDGSLLadgktpaSYDYNVDVTRRVTEMAHAVGVSVEGELG 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 177 C-------TGGEEDGVD-NSDMDASELYTSPEDVAYAYEKLNAIShrftIAASFGNVHGVYK-----PGNVVLTPTIlrd 243
Cdd:PRK13399 145 ClgsletgEAGEEDGVGaEGKLSHDQMLTDPDQAVDFVQRTGVDA----LAIAIGTSHGAYKftrkpDGDILAIDRI--- 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 244 sqAYVSEKfgLPANSLnfVFHGGS---------------------GSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQY 302
Cdd:PRK13399 218 --EEIHAR--LPNTHL--VMHGSSsvpqelqeiinayggkmketyGVPVEEIQRGIKHGVRKVNIDTDIRLAMTGAIRKV 291

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 491624905 303 EAEnhdylqgqignptgedapNKKYYDPRVWLRAGQASMVTRLEQAF 349
Cdd:PRK13399 292 LAE------------------HPSEFDPRKALKPAMKAMTALCKQRF 320
PLN02858 PLN02858
fructose-bisphosphate aldolase
 25-300 5.56e-17

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 82.59  E-value: 5.56e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905   25 AKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGgaaffagkglklegqeAQILGAVAGAKYVHAVAEAYGVPV 104
Cdd:PLN02858 1109 AEKGGYAVGAFNVYNLEGIEAVVAAAEAEKSPAILQVHPG----------------ALKQGGIPLVSCCIAAAEQASVPI 1172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  105 ILHTDHAAKKllpwiDGLLDAGEeyfaqTGkplFSSHMIDLSEESLEENIEISaKYLERMAK-MNMTLEIELGCTGGEED 183
Cdd:PLN02858 1173 TVHFDHGTSK-----HELLEALE-----LG---FDSVMVDGSHLSFTENISYT-KSISSLAHsKGLMVEAELGRLSGTED 1238

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  184 GVDNSDMDASelytsPEDVAYAYEKLNAISHRfTIAASFGNVHGVYKPGNVVLTPTILRDSQAYVSEKfglpanSLNFVF 263
Cdd:PLN02858 1239 GLTVEEYEAK-----LTDVDQAKEFIDETGID-ALAVCIGNVHGKYPASGPNLRLDLLKELRALSSKK------GVLLVL 1306

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 491624905  264 HGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIR 300
Cdd:PLN02858 1307 HGASGLPESLIKECIENGVRKFNVNTEVRTAYMEALS 1343
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
20-306 9.00e-17

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 80.02  E-value: 9.00e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905  20 KVFEVAKENHFALPAVNCVGTDSVNAVLEAAAKVKAPVIVQFSNGGAAFFagkGLKLEGQEAQILGAvagaKYVHavaea 99
Cdd:PRK05835   7 EILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYM---GIDMAVGMVKIMCE----RYPH----- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 100 ygVPVILHTDHAAKKllpwidglldageEYFAQTGKPLFSSHMIDLSEESLEENIEISAKYLERMAKMNMTLEIELGCTG 179
Cdd:PRK05835  75 --IPVALHLDHGTTF-------------ESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLM 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491624905 180 GEEDGVDNSDMDAseLYTSPEDVayayEKLNAISHRFTIAASFGNVHGVYK-PGNVVL-------------TPTILRDSQ 245
Cdd:PRK05835 140 GIEDNISVDEKDA--VLVNPKEA----EQFVKESQVDYLAPAIGTSHGAFKfKGEPKLdferlqevkrltnIPLVLHGAS 213

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491624905 246 A---YVSEKFGLPANSLNfvfhGGSGSSLEEIRESIGYGVIKMNIDTDTQWATWDGIRQYEAEN 306
Cdd:PRK05835 214 AipdDVRKSYLDAGGDLK----GSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANED 273
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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