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Conserved domains on  [gi|491880879|ref|WP_005649741|]
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MULTISPECIES: PH domain-containing protein [Parabacteroides]

Protein Classification

PH domain-containing protein( domain architecture ID 141072)

bacterial Pleckstrin homology (bPH) domain-containing protein may be involved in protein-protein interactions; similar to Mycobacterium tuberculosis low molecular weight protein antigen 6 (CFP-6)

CATH:  2.30.29.50
Gene Ontology:  GO:0005515
PubMed:  15493994|22728242|19913036|17233582
SCOP:  4002395

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
bPH_4 super family cl19751
Bacterial PH domain; This family consists of several hypothetical proteins specific to ...
 62-153 8.98e-12

Bacterial PH domain; This family consists of several hypothetical proteins specific to Oceanobacillus and Bacillus species. Members of this family are typically around 130 residues in length. The function of this family is unknown. Members of this family have a PH domain like structure.


The actual alignment was detected with superfamily member pfam10882:

Pssm-ID: 388627  Cd Length: 100  Bit Score: 58.04  E-value: 8.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491880879   62 RFIVDGEKLVIDAYFRKTYINIEEILSAREVDRLDLGImiRSFGVGWLFGDLGYFSSTAIGRVKVFARRSDNRILITTsR 141
Cdd:pfam10882   2 RYSLDDEGLVIRWIFGKVKIPLSDIEAVRVVEGVIKGV--RLFGTGKPGYALGRFYIHDIGIAYMYATRLKRVLLLKT-K 78

                          90
                  ....*....|..
gi 491880879  142 RGNFIIAPDDPE 153
Cdd:pfam10882  79 DKIYGISPENFE 90
 
Name Accession Description Interval E-value
bPH_5 pfam10882
Bacterial PH domain; This family of proteins with unknown function appear to be related to ...
 62-153 8.98e-12

Bacterial PH domain; This family of proteins with unknown function appear to be related to bacterial PH domains. This family was formerly known as DUF2679.


Pssm-ID: 378504  Cd Length: 100  Bit Score: 58.04  E-value: 8.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491880879   62 RFIVDGEKLVIDAYFRKTYINIEEILSAREVDRLDLGImiRSFGVGWLFGDLGYFSSTAIGRVKVFARRSDNRILITTsR 141
Cdd:pfam10882   2 RYSLDDEGLVIRWIFGKVKIPLSDIEAVRVVEGVIKGV--RLFGTGKPGYALGRFYIHDIGIAYMYATRLKRVLLLKT-K 78

                          90
                  ....*....|..
gi 491880879  142 RGNFIIAPDDPE 153
Cdd:pfam10882  79 DKIYGISPENFE 90
 
Name Accession Description Interval E-value
bPH_5 pfam10882
Bacterial PH domain; This family of proteins with unknown function appear to be related to ...
 62-153 8.98e-12

Bacterial PH domain; This family of proteins with unknown function appear to be related to bacterial PH domains. This family was formerly known as DUF2679.


Pssm-ID: 378504  Cd Length: 100  Bit Score: 58.04  E-value: 8.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491880879   62 RFIVDGEKLVIDAYFRKTYINIEEILSAREVDRLDLGImiRSFGVGWLFGDLGYFSSTAIGRVKVFARRSDNRILITTsR 141
Cdd:pfam10882   2 RYSLDDEGLVIRWIFGKVKIPLSDIEAVRVVEGVIKGV--RLFGTGKPGYALGRFYIHDIGIAYMYATRLKRVLLLKT-K 78

                          90
                  ....*....|..
gi 491880879  142 RGNFIIAPDDPE 153
Cdd:pfam10882  79 DKIYGISPENFE 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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