NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|491909364|ref|WP_005665546|]
View 

IS481 family transposase [Massilia timonae]

Protein Classification

transposase family protein( domain architecture ID 1750099)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0046872|GO:0003676|GO:0006310
PubMed:  11774877

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
transpos_IS481 NF033577
IS481 family transposase; null
19-299 5.01e-87

IS481 family transposase; null


:

Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 262.53  E-value: 5.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  19 IKDSGLSDRQAAKVFNVSRATAKKWLKR------DDVQDRSHRAHVLKTTLSAAQEAIVLALRQSLYLPLDDLLFVTKQY 92
Cdd:NF033577   9 VLEDGWSVREAARRFGISRKTVYKWLKRyraggeEGLIDRSRRPHRSPRRTSPETEARILALRRELRLGPRRIAYELERQ 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  93 INPdVSRSGLARLLKREGMSRLEDVIPKAegetiAPKKTFK-DYEPGFVHIDIKYLPQMPDETsRRYLFVAIDRATRWVF 171
Cdd:NF033577  89 GPG-VSRSTVHRILRRHGLSRLRALDRKT-----GKVKRYErAHPGELWHIDIKKLGRIPDVG-RLYLHTAIDDHSRFAY 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 172 MHIYGDMTDKSSVDFLRRLKLASPIKISKILTDNGSQFTDRFatkdkkpsgnHAFDVACTALPAEHRLAPPRHPQTNGMV 251
Cdd:NF033577 162 AELYPDETAETAADFLRRAFAEHGIPIRRVLTDNGSEFRSRA----------HGFELALAELGIEHRRTRPYHPQTNGKV 231
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 491909364 252 ERFNGRI-NELLQQTRFDSRADLEATLMNYLKLYNHHIPQRAIDSKTPI 299
Cdd:NF033577 232 ERFHRTLkDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPA 280
 
Name Accession Description Interval E-value
transpos_IS481 NF033577
IS481 family transposase; null
19-299 5.01e-87

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 262.53  E-value: 5.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  19 IKDSGLSDRQAAKVFNVSRATAKKWLKR------DDVQDRSHRAHVLKTTLSAAQEAIVLALRQSLYLPLDDLLFVTKQY 92
Cdd:NF033577   9 VLEDGWSVREAARRFGISRKTVYKWLKRyraggeEGLIDRSRRPHRSPRRTSPETEARILALRRELRLGPRRIAYELERQ 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  93 INPdVSRSGLARLLKREGMSRLEDVIPKAegetiAPKKTFK-DYEPGFVHIDIKYLPQMPDETsRRYLFVAIDRATRWVF 171
Cdd:NF033577  89 GPG-VSRSTVHRILRRHGLSRLRALDRKT-----GKVKRYErAHPGELWHIDIKKLGRIPDVG-RLYLHTAIDDHSRFAY 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 172 MHIYGDMTDKSSVDFLRRLKLASPIKISKILTDNGSQFTDRFatkdkkpsgnHAFDVACTALPAEHRLAPPRHPQTNGMV 251
Cdd:NF033577 162 AELYPDETAETAADFLRRAFAEHGIPIRRVLTDNGSEFRSRA----------HGFELALAELGIEHRRTRPYHPQTNGKV 231
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 491909364 252 ERFNGRI-NELLQQTRFDSRADLEATLMNYLKLYNHHIPQRAIDSKTPI 299
Cdd:NF033577 232 ERFHRTLkDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPA 280
Tra8 COG2826
Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];
9-308 2.32e-32

Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];


Pssm-ID: 442074 [Multi-domain]  Cd Length: 325  Bit Score: 122.68  E-value: 2.32e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364   9 ARTTPKTRQEI---KDSGLSDRQAAKVFNVSRATAKKWLKRDDV-------------QDRSHRAH-VLKTTLSAAQEAIV 71
Cdd:COG2826    5 KHLTLEEREEIealLKAGLSVREIARRLGRSPSTISRELKRNSGrrgyraegaqrlaEDRRRRPKrKRKLATTPELRAYV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  72 LA-LRQSLylPLDDLLFVTK---------------QYINPDVSRSGLARLLKREGMSRledvIPKAEGETIAPKKTF--- 132
Cdd:COG2826   85 EEkLRKKW--SPEQIAGRLKreddpgmrvshetiyRYIYAGGLRKDLYRPLRRKRKRR----RPRGRTRKRRGKIPDrrs 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 133 -----KDY----EPGFVHIDIKYLPQmpdetSRRYLFVAIDRATRWVFM-HIyGDMTDKSSVDFLRRLKLASPIKISK-I 201
Cdd:COG2826  159 iserpAEVedraEPGHWEGDLIIGKR-----GKSALLTLVERKSRFVILlKL-PDKTAESVADALIRLLRKLPAFLRKsI 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 202 LTDNGSQFTDrfatkdkkpsgnhaFDVACTALPAEHRLAPPRHPQTNGMVERFNGRINE-LLQQTRFDSraDLEATLMNY 280
Cdd:COG2826  233 TTDNGKEFAD--------------HKEIEAALGIKVYFADPYSPWQRGTNENTNGLLRQyFPKGTDFST--VTQEELDAI 296
                        330       340
                 ....*....|....*....|....*...
gi 491909364 281 LKLYNhHIPQRAIDSKTPILALKEWQKK 308
Cdd:COG2826  297 ADRLN-NRPRKCLGYKTPAEVFAEELAA 323
transpos_IS3 NF033516
IS3 family transposase;
27-299 8.14e-15

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 74.14  E-value: 8.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  27 RQAAKVFNVSRATAKKWLKRDDVQDRSHRAHVLKTTLSAAQEA--------IVLALRQSLYLplddllfvtkqyinpdVS 98
Cdd:NF033516 104 RRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESrgrygyrrITALLRREGIR----------------VN 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  99 RSGLARLLKREGMS------RLEDVIPKAEGETIAP---KKTFKDYEPG--FVhIDIKYLPqmpdeTSRR--YLFVAIDR 165
Cdd:NF033516 168 HKRVYRLMRELGLLarrrrkRRPYTTDSGHVHPVAPnllNRQFTATRPNqvWV-TDITYIR-----TAEGwlYLAVVLDL 241
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 166 ATR----WvfmHIYGDMTDKSSVDFLRRLKLASPIKISKIL-TDNGSQFTdrfatkdkkpsgNHAFDVACTALPAEHRLA 240
Cdd:NF033516 242 FSReivgW---SVSTSMSAELVLDALEMAIEWRGKPEGLILhSDNGSQYT------------SKAYREWLKEHGITQSMS 306
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 241 PPRHPQTNGMVERFNGRI-NELLQQTRFDSRADLEATLMNYLKLYNHHIPQRAIDSKTPI 299
Cdd:NF033516 307 RPGNCWDNAVAESFFGTLkRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPA 366
rve_3 pfam13683
Integrase core domain;
236-298 1.35e-13

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 64.93  E-value: 1.35e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491909364  236 EHRLAPPRHPQTNGMVERFNGRI-NELLQQTRFDSRADLEATLMNYLKLYNHHIPQRAIDSKTP 298
Cdd:pfam13683   4 EISYIAPGKPMQNGLVESFNGTLrDECLNEHLFSSLAEARALLAAWREDYNTERPHSSLGYRTP 67
transpos_IS630 NF033545
IS630 family transposase;
19-282 1.58e-11

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 63.81  E-value: 1.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  19 IKDSGLSDRQAAKVFNVSRATAKKWLKR------DDVQDRSHRAHvlKTTLSAAQEAIVLALRQS------LYLPLDDLL 86
Cdd:NF033545   8 LAAEGLSITEIAERLGVSRSTVYRWLKRfnegglEGLLDKPRPGR--PRKLLSEQQAELLALLLEeppegaGHWTLRELA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  87 FVTKQYINPDVSRSGLARLLKREGMSRLEdVIPKAEGETIAPKKTFKDY-----------------EPGFVHID-IKYLP 148
Cdd:NF033545  86 ALLEEEFGVEYSRSTVRRLLKRLGLSPKK-PRPRAPKQDPEFVEKFKEVlglyrappdpaevvfidESGIQLLDtRGRGW 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 149 QMPDETSRR----------YLFVAIDRATRWVFMHIYGDMTDKSSVDFLRRLKLASPIKISKILTDNGSQFTDRfATKDK 218
Cdd:NF033545 165 APKGQRRPRvhvygrrgtlNLFGALDPLTGKVFVLFTGRINSEDFIEFLEELLAAYPGKKIHLILDNASTHKSK-KVREW 243
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491909364 219 KPSGNHaFDVactalpaeHRLaPPRHPQTNgMVERFNGRINE-LLQQTRFDSRADLEATLMNYLK 282
Cdd:NF033545 244 LEEHGR-IEL--------HYL-PPYSPWLN-PIERVWAVLKRrLLRNRAFRSVDELREAIDAFLN 297
transpos_IS21 NF033546
IS21 family transposase;
23-312 2.51e-07

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 51.44  E-value: 2.51e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  23 GLSDRQAAKVFNVSRATAKKWLKRDD-VQDRSHRAHVLKTTLSAAQEAIvlalrqslylpLDDLLFVTKQyiNPDVSRSG 101
Cdd:NF033546   8 GLSIREIARELGISRNTVRKYLRRAGlDEPPKYERRPPRPSKLDPFEPY-----------IPDWLEAHLR--KPGVTATL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 102 LARLLKREG----MSRLEDVIPKAEGETIAPKKTFK-DYEPG------FVHIDIkylpQMPDETSRR-YLFVAIDRATRW 169
Cdd:NF033546  75 LWEELRAEGypgsYSTVRRYVRRWRAEQGPAKVFVRlEHAPGeqaqvdFGEATV----VVTGGTGKIlHVFVAVLGYSRY 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 170 VFMHIYGDMTDKSSVDFLRR----------------LKLAspikISKILTDNGSQFTDRFAtkdkkpsgnhAFdvactal 233
Cdd:NF033546 151 TYVEATPSESQEDLLDGHQRafeffggvpreivydnLKTA----VDKRDRYEEPRLNPRFA----------AF------- 209
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 234 pAEH-----RLAPPRHPQTNGMVERFNGRINE---LLQQTRFDSRADLEATLMNYLKLYNHHIPQRaidsKTPILALKEW 305
Cdd:NF033546 210 -AAHygfepRPCRPYRPQEKGKVERAVGYVRRwflRLRGRRFESLAELNAALAEWLAELANQRPHG----TTGGSPAERF 284

                 ....*..
gi 491909364 306 QKKRPEL 312
Cdd:NF033546 285 EEERPAL 291
 
Name Accession Description Interval E-value
transpos_IS481 NF033577
IS481 family transposase; null
19-299 5.01e-87

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 262.53  E-value: 5.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  19 IKDSGLSDRQAAKVFNVSRATAKKWLKR------DDVQDRSHRAHVLKTTLSAAQEAIVLALRQSLYLPLDDLLFVTKQY 92
Cdd:NF033577   9 VLEDGWSVREAARRFGISRKTVYKWLKRyraggeEGLIDRSRRPHRSPRRTSPETEARILALRRELRLGPRRIAYELERQ 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  93 INPdVSRSGLARLLKREGMSRLEDVIPKAegetiAPKKTFK-DYEPGFVHIDIKYLPQMPDETsRRYLFVAIDRATRWVF 171
Cdd:NF033577  89 GPG-VSRSTVHRILRRHGLSRLRALDRKT-----GKVKRYErAHPGELWHIDIKKLGRIPDVG-RLYLHTAIDDHSRFAY 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 172 MHIYGDMTDKSSVDFLRRLKLASPIKISKILTDNGSQFTDRFatkdkkpsgnHAFDVACTALPAEHRLAPPRHPQTNGMV 251
Cdd:NF033577 162 AELYPDETAETAADFLRRAFAEHGIPIRRVLTDNGSEFRSRA----------HGFELALAELGIEHRRTRPYHPQTNGKV 231
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 491909364 252 ERFNGRI-NELLQQTRFDSRADLEATLMNYLKLYNHHIPQRAIDSKTPI 299
Cdd:NF033577 232 ERFHRTLkDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPA 280
Tra8 COG2826
Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];
9-308 2.32e-32

Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];


Pssm-ID: 442074 [Multi-domain]  Cd Length: 325  Bit Score: 122.68  E-value: 2.32e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364   9 ARTTPKTRQEI---KDSGLSDRQAAKVFNVSRATAKKWLKRDDV-------------QDRSHRAH-VLKTTLSAAQEAIV 71
Cdd:COG2826    5 KHLTLEEREEIealLKAGLSVREIARRLGRSPSTISRELKRNSGrrgyraegaqrlaEDRRRRPKrKRKLATTPELRAYV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  72 LA-LRQSLylPLDDLLFVTK---------------QYINPDVSRSGLARLLKREGMSRledvIPKAEGETIAPKKTF--- 132
Cdd:COG2826   85 EEkLRKKW--SPEQIAGRLKreddpgmrvshetiyRYIYAGGLRKDLYRPLRRKRKRR----RPRGRTRKRRGKIPDrrs 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 133 -----KDY----EPGFVHIDIKYLPQmpdetSRRYLFVAIDRATRWVFM-HIyGDMTDKSSVDFLRRLKLASPIKISK-I 201
Cdd:COG2826  159 iserpAEVedraEPGHWEGDLIIGKR-----GKSALLTLVERKSRFVILlKL-PDKTAESVADALIRLLRKLPAFLRKsI 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 202 LTDNGSQFTDrfatkdkkpsgnhaFDVACTALPAEHRLAPPRHPQTNGMVERFNGRINE-LLQQTRFDSraDLEATLMNY 280
Cdd:COG2826  233 TTDNGKEFAD--------------HKEIEAALGIKVYFADPYSPWQRGTNENTNGLLRQyFPKGTDFST--VTQEELDAI 296
                        330       340
                 ....*....|....*....|....*...
gi 491909364 281 LKLYNhHIPQRAIDSKTPILALKEWQKK 308
Cdd:COG2826  297 ADRLN-NRPRKCLGYKTPAEVFAEELAA 323
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
97-309 5.67e-21

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 91.37  E-value: 5.67e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  97 VSRSGLARLLKREGMSRLEDVIPK-----AEGETIAPKKTFKDYEPGFV-HIDIKYLPqMPDEtsRRYLFVAIDRATR-W 169
Cdd:COG2801  103 VNRKRVRRLMRELGLQARRRRKKKyttysGHGGPIAPNLLFTATAPNQVwVTDITYIP-TAEG--WLYLAAVIDLFSReI 179
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 170 VFMHIYGDMTDKSSVDFLRRLKLASPIKISKIL-TDNGSQFTdrfatkdkkpsgNHAFDVACTALPAEHRLAPPRHPQTN 248
Cdd:COG2801  180 VGWSVSDSMDAELVVDALEMAIERRGPPKPLILhSDNGSQYT------------SKAYQELLKKLGITQSMSRPGNPQDN 247
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491909364 249 GMVERFNGRI-NELLQQTRFDSRADLEATLMNYLKLYNHHIPQRAIDSKTPILALKEWQKKR 309
Cdd:COG2801  248 AFIESFFGTLkYELLYRRRFESLEEAREAIEEYIEFYNHERPHSSLGYLTPAEYEKQLAAAA 309
transpos_IS3 NF033516
IS3 family transposase;
27-299 8.14e-15

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 74.14  E-value: 8.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  27 RQAAKVFNVSRATAKKWLKRDDVQDRSHRAHVLKTTLSAAQEA--------IVLALRQSLYLplddllfvtkqyinpdVS 98
Cdd:NF033516 104 RRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESrgrygyrrITALLRREGIR----------------VN 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  99 RSGLARLLKREGMS------RLEDVIPKAEGETIAP---KKTFKDYEPG--FVhIDIKYLPqmpdeTSRR--YLFVAIDR 165
Cdd:NF033516 168 HKRVYRLMRELGLLarrrrkRRPYTTDSGHVHPVAPnllNRQFTATRPNqvWV-TDITYIR-----TAEGwlYLAVVLDL 241
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 166 ATR----WvfmHIYGDMTDKSSVDFLRRLKLASPIKISKIL-TDNGSQFTdrfatkdkkpsgNHAFDVACTALPAEHRLA 240
Cdd:NF033516 242 FSReivgW---SVSTSMSAELVLDALEMAIEWRGKPEGLILhSDNGSQYT------------SKAYREWLKEHGITQSMS 306
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 241 PPRHPQTNGMVERFNGRI-NELLQQTRFDSRADLEATLMNYLKLYNHHIPQRAIDSKTPI 299
Cdd:NF033516 307 RPGNCWDNAVAESFFGTLkRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPA 366
rve_3 pfam13683
Integrase core domain;
236-298 1.35e-13

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 64.93  E-value: 1.35e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491909364  236 EHRLAPPRHPQTNGMVERFNGRI-NELLQQTRFDSRADLEATLMNYLKLYNHHIPQRAIDSKTP 298
Cdd:pfam13683   4 EISYIAPGKPMQNGLVESFNGTLrDECLNEHLFSSLAEARALLAAWREDYNTERPHSSLGYRTP 67
transpos_IS630 NF033545
IS630 family transposase;
19-282 1.58e-11

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 63.81  E-value: 1.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  19 IKDSGLSDRQAAKVFNVSRATAKKWLKR------DDVQDRSHRAHvlKTTLSAAQEAIVLALRQS------LYLPLDDLL 86
Cdd:NF033545   8 LAAEGLSITEIAERLGVSRSTVYRWLKRfnegglEGLLDKPRPGR--PRKLLSEQQAELLALLLEeppegaGHWTLRELA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  87 FVTKQYINPDVSRSGLARLLKREGMSRLEdVIPKAEGETIAPKKTFKDY-----------------EPGFVHID-IKYLP 148
Cdd:NF033545  86 ALLEEEFGVEYSRSTVRRLLKRLGLSPKK-PRPRAPKQDPEFVEKFKEVlglyrappdpaevvfidESGIQLLDtRGRGW 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 149 QMPDETSRR----------YLFVAIDRATRWVFMHIYGDMTDKSSVDFLRRLKLASPIKISKILTDNGSQFTDRfATKDK 218
Cdd:NF033545 165 APKGQRRPRvhvygrrgtlNLFGALDPLTGKVFVLFTGRINSEDFIEFLEELLAAYPGKKIHLILDNASTHKSK-KVREW 243
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491909364 219 KPSGNHaFDVactalpaeHRLaPPRHPQTNgMVERFNGRINE-LLQQTRFDSRADLEATLMNYLK 282
Cdd:NF033545 244 LEEHGR-IEL--------HYL-PPYSPWLN-PIERVWAVLKRrLLRNRAFRSVDELREAIDAFLN 297
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
141-245 3.50e-11

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 58.86  E-value: 3.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  141 HIDIKYLPqMPDETSRRYLFVAIDRATRWVFMHIYGDMTDKSSV-DFLRRLKLASPIKISKILTDNGSQFTDRfatkdkk 219
Cdd:pfam00665   6 QGDFTYIR-IPGGGGKLYLLVIVDDFSREILAWALSSEMDAELVlDALERAIAFRGGVPLIIHSDNGSEYTSK------- 77
                          90       100
                  ....*....|....*....|....*.
gi 491909364  220 psgnhAFDVACTALPAEHRLAPPRHP 245
Cdd:pfam00665  78 -----AFREFLKDLGIKPSFSRPGNP 98
transpos_IS21 NF033546
IS21 family transposase;
23-312 2.51e-07

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 51.44  E-value: 2.51e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  23 GLSDRQAAKVFNVSRATAKKWLKRDD-VQDRSHRAHVLKTTLSAAQEAIvlalrqslylpLDDLLFVTKQyiNPDVSRSG 101
Cdd:NF033546   8 GLSIREIARELGISRNTVRKYLRRAGlDEPPKYERRPPRPSKLDPFEPY-----------IPDWLEAHLR--KPGVTATL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 102 LARLLKREG----MSRLEDVIPKAEGETIAPKKTFK-DYEPG------FVHIDIkylpQMPDETSRR-YLFVAIDRATRW 169
Cdd:NF033546  75 LWEELRAEGypgsYSTVRRYVRRWRAEQGPAKVFVRlEHAPGeqaqvdFGEATV----VVTGGTGKIlHVFVAVLGYSRY 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 170 VFMHIYGDMTDKSSVDFLRR----------------LKLAspikISKILTDNGSQFTDRFAtkdkkpsgnhAFdvactal 233
Cdd:NF033546 151 TYVEATPSESQEDLLDGHQRafeffggvpreivydnLKTA----VDKRDRYEEPRLNPRFA----------AF------- 209
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 234 pAEH-----RLAPPRHPQTNGMVERFNGRINE---LLQQTRFDSRADLEATLMNYLKLYNHHIPQRaidsKTPILALKEW 305
Cdd:NF033546 210 -AAHygfepRPCRPYRPQEKGKVERAVGYVRRwflRLRGRRFESLAELNAALAEWLAELANQRPHG----TTGGSPAERF 284

                 ....*..
gi 491909364 306 QKKRPEL 312
Cdd:NF033546 285 EEERPAL 291
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
21-292 4.89e-07

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 50.62  E-value: 4.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  21 DSGLSDRQAAKVFNVSRATAKKWLKR------DDVQDRSHRAHvlKTTLSAAQEAIVLALRQSLYLP------LDDLLFV 88
Cdd:COG3415   36 AEGLSVREIAERLGVSRSTVYRWLKRyregglAGLKDRPRGGR--PSKLSDEQRERLLELLREKSPDqgsrwtLAELAEL 113
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  89 TKQYINPDVSRSGLARLLKREGMSRLEDVIPKAEGETIAPKKTFKDYEPGFVHIDIKYLPQMPDETSRRYLFVAIDRATR 168
Cdd:COG3415  114 LEEEFGVEVSPSTVRRLLKRLGLSYKKPRPRAPKQDPEAVEKFKKELEALLAKPAKAEVAGVDEGDEIGALRRAAGGRLL 193
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 169 WVFMHIYGDMTDKSSVDFLRRLKLASPIKISKILTDNGSQFTDRFATKDKkpsgnHAFDVACTALPAEHRLAPPRHPQTN 248
Cdd:COG3415  194 APGGRVRRTGASVRRGRALLFLALGLALGLRIGLTIDALLAGALLLFLRL-----LAERALALLLLLLLLLLLSPSKAVA 268
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 491909364 249 GMVERFNGRINELLQQTRFDSRADLEATLMNYLKLYNHHIPQRA 292
Cdd:COG3415  269 RAAKLLKLELLRLLFLPPSASLLLALEALLRELRERNLLRLAHA 312
COG4584 COG4584
Transposase [Mobilome: prophages, transposons];
12-312 1.04e-06

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 443641 [Multi-domain]  Cd Length: 484  Bit Score: 49.84  E-value: 1.04e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  12 TPKTRQEIKD---SGLSDRQAAKVFNVSRATAKKWLKRD-DVQDRSHRAHVLKTTLSAAQEAIVLALRQslylplddllf 87
Cdd:COG4584    3 TMEQIREIRRllrEGLSIREIARELGISRNTVRKYLRRAeEWPELYPRRRPRPSKLDPYKEYIDEWLEE----------- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364  88 vtkqyiNPDVSRSGLARLLKRE-----GMSRLEDVIpKAEGETIAPKKTFK-DYEPG------FVHidiKYLPQMPDETS 155
Cdd:COG4584   72 ------GPRVTAKRIWEELKEEhgytgSYSTVRRYV-RRLRPEYPKEAFVRlEHPPGeqaqvdWGE---ATVPPITGERR 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 156 RRYLFVAIDRATRWVFMHIYGDMTdksSVDFLRRLKLA------SPikiSKILTDNGSQFTDRFATKDKKPsgNHAFdva 229
Cdd:COG4584  142 KVYVFVAVLGYSRYKYVEAYPSQT---QEDLLEAHVRAfeffggVP---REIVYDNLKTAVTKADRGEPVL--NERF--- 210
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 230 cTALpAEH-----RLAPPRHPQTNGMVERFNGRI--NELLQQTRFDSRADLEATLMNYLKLYNHHIPQRAIDsKTPILAL 302
Cdd:COG4584  211 -LAF-AAHygfepRPCRPRRPKEKGKVENAVGYVrrNFLAPRPRFTSLEELNAALLEWLERVANRRIHGTTG-ESPAERF 287
                        330
                 ....*....|
gi 491909364 303 KEWQKKRPEL 312
Cdd:COG4584  288 AEEEEALLPL 297
Rve COG3316
Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];
152-299 1.09e-04

Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];


Pssm-ID: 442545 [Multi-domain]  Cd Length: 235  Bit Score: 42.97  E-value: 1.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491909364 152 DET------SRRYLFVAIDRATRWVFMHIYGDMTDKSSVDFLRRLKLASPIKISKILTDngsqftdrfatkdkkpsGNHA 225
Cdd:COG3316   76 DETyikikgKWHYLYRAVDAEGRILDFLLSPRRDTKAAKRFLRKALKKYGLKPRVIVTD-----------------KLPS 138
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491909364 226 FDVACTALpAEHRLAPPRHPQT---NGMVERFNGRINELLQQTR-FDSRADLEATLMNYLKLYNHHIPQRAIDSKTPI 299
Cdd:COG3316  139 YGAALREL-KPEGGLGVEHRQVkglNNRIERDHRTLKRRERPMRgFKSFRTAQRFLSGFEAYYNFRRPHRSLNGATPA 215
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH