|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
3-1029 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 839.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 3 NIVKFAVGNPVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQFVKNMESmAIRQ-SDVTQV 81
Cdd:COG0841 2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEE-ALNGvEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 82 SSVIKAGTARITVEYTWTKDMDEAFLDLQKAMNPFAQN--KEITELKITQHDANLSPVVLVGMSHQNItDMAELRRIAES 159
Cdd:COG0841 81 TSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDlpEDVEPPGVTKVNPSDFPVMVLALSSDDL-DELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 160 YIRNELIRLEGVAEVTLSGEEVTTLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSELGLQYLVKSSSLFSTEAD 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 240 FENLIVGYKpvqqetsgnsssetvtdlNKAPVFLKEVATVQFVNARPENIVRINGKRSIGLSIYKEMRFNTVKVVDEVTS 319
Cdd:COG0841 240 FENIVIRTN------------------DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRA 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 320 RLAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNLMFFNGL 398
Cdd:COG0841 302 KLEELQASLPeGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGF 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 399 TLNIMTLGGLALGAGMLVDNAIVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGASGELFKD 478
Cdd:COG0841 382 SLNILTLFALVLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQ 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 479 QAWTVTFSLVSSLFVAILVIPMLYTQLSGKKVKMEEVKSIRIT---------RYSKILRKLVRHRWWVIGMAVLLLVVTG 549
Cdd:COG0841 462 FALTVAIALLISLFVALTLTPALCARLLKPHPKGKKGRFFRAFnrgfdrltrGYGRLLRWALRHRKLTLLVALALLALSV 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 550 LLTPFIGTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDLLYTIVGGDSlctIYSHVGEGSGSEnaifeGENTAMM 629
Cdd:COG0841 542 LLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVES---VFSVVGFSGGGS-----GSNSGTI 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 630 KIIL--FPECILSPENVIARFLEEAKNPDGLELSIRQdensLSSLLGSEGAPIVVEVKGEELDEIAKITGEVKERMQEVD 707
Cdd:COG0841 614 FVTLkpWDERDRSADEIIARLREKLAKIPGARVFVFQ----PPAGGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIP 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 708 GVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEAGKMEYRGEMRDIVIKVPD---ISLGALGSLVI 784
Cdd:COG0841 690 GLVDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEedrNSPEDLENLYV 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 785 RSGT-QEFLLDEIASITHGQAPKEILRRNQSRIGKIMANMDTGKSLDKVAAEVRLAVKDIDLPANYSITVTGEEEKRQES 863
Cdd:COG0841 770 RTPDgEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQES 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 864 MHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSIILVDRI 943
Cdd:COG0841 850 FSSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFA 929
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 944 NQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRSPMAIAVIGGLITSTLMSLMVIPCVYYVLE 1023
Cdd:COG0841 930 NQLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLD 1009
|
....*.
gi 491930720 1024 KIKRRI 1029
Cdd:COG0841 1010 RLRRRL 1015
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
4-1023 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 595.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 4 IVKFAVGNPVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQFVKNMESMAIRQSDVTQVSS 83
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 84 VIKAGTARITVEYTWTKDMDEAFLDLQKAMNPfAQNK---EITELKITQHDANLSPVVLVGM-SHQNITDMAELRRIAES 159
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQL-ATPLlpeGVQRPGISVIKTSLGPIMVLAVtSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 160 YIRNELIRLEGVAEVTLSGEEVTTLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSELGLQYLVKSSSLFSTEAD 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 240 FENLIVGYKpvqqetsgnsssetvtdlNKAPVFLKEVATVQFVNARPENIVRINGKRSIGLSIYKEMRFNTVKVVDEVTS 319
Cdd:pfam00873 240 FEKIIVKNQ------------------DGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRA 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 320 RLAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNLMFFNGL 398
Cdd:pfam00873 302 KLAELKPTFPqGVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGF 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 399 TLNIMTLGGLALGAGMLVDNAIVVIESIFRN-QEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGASGELFK 477
Cdd:pfam00873 382 SINTLTLGGLVLAIGLVVDDAIVVVENIERVlEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFR 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 478 DQAWTVTFSLVSSLFVAILVIPMLYTQLSGKKVKMEEVKSIR---------ITRYSKILRKLVRHRWWVIGMAVLLLVVT 548
Cdd:pfam00873 462 QFAITIVLAILLSVLVALTLTPALCATLLKPRREPKHGGFFRwfnrmfdrlTRGYAKLLAKVLRHTAVVLLVALLLVVGS 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 549 GLLTPFIGTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDLLYTIVGGDSLctiyshVGEGSGSENAIFEGENTAM 628
Cdd:pfam00873 542 VWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESV------FAVTGFAFSGDNNGPNSGD 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 629 MKIILFPE-----CILSPENVIARFLEEAKNPDGLELSIrQDENSLSSLLGSEG--APIVVEVKGEELDEIAKITGEVKE 701
Cdd:pfam00873 616 AFISLKPWkerpgPEKSVQALIERLRKALKQIPGANVFL-FQPIQLRGLGTISGfrSDLQVKIFGDDLDALDEARNQILA 694
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 702 RMQEVDGVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEAGKMEYRGEMRDIVIKVPD---ISLGA 778
Cdd:pfam00873 695 ALAQLPGLSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEdfrSSPED 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 779 LGSLVIRSGTQEFL-LDEIASITHGQAPKEILRRNQSRIGKIMANMDTGKSLDKVAAEVRLAVKDIDLPANYSITVTGEE 857
Cdd:pfam00873 775 IGQLYVRNPYGKMIpLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQF 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 858 EKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSI 937
Cdd:pfam00873 855 EQEQLAGNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAI 934
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 938 ILVDRINQL-SQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRSPMAIAVIGGLITSTLMSLMVIP 1016
Cdd:pfam00873 935 LMVEFANELrEQEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVP 1014
|
....*..
gi 491930720 1017 CVYYVLE 1023
Cdd:pfam00873 1015 VFYVLFH 1021
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1028 |
3.57e-177 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 544.24 E-value: 3.57e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 1 MKNIVKFAVGNPVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQfV-----KNMESMAirq 75
Cdd:COG3696 2 LNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQ-VtypieTALNGLP--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 76 sDVTQVSSVIKAGTARITVEYTWTKDMDeafldlqkamnpFAQNkEITElKITQHDANLSPVVLVGM------------- 142
Cdd:COG3696 78 -GVKEVRSISRFGLSVVTVIFEDGTDIY------------WARQ-LVLE-RLQQVREQLPAGVTPELgpistglgeiyqy 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 143 ---SHQNITDMAELRRIAESYIRNELIRLEGVAEVTLSGEEVTTLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRV 219
Cdd:COG3696 143 tleSDPGKYSLMELRTLQDWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYI 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 220 SELGLQYLVKSSSLFSTEADFENLIVGYKpvqqetsgnsssetvtdlNKAPVFLKEVATVQFVNARPENIVRINGKR-SI 298
Cdd:COG3696 223 ERGGQEYLVRGIGLIRSLEDIENIVVKTR------------------NGTPVLLRDVAEVRIGPAPRRGAATLNGEGeVV 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 299 GLSIykEMRF--NTVKVVDEVTSRLAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTT 375
Cdd:COG3696 285 GGIV--LMLKgeNALEVIEAVKAKLAELKPSLPeGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAA 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 376 LIVSLSIPISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFR------NQEKGVSVKEAVVTGTAEVAN 449
Cdd:COG3696 363 LIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDFGIIVDGAVVMVENILRrleenrAAGTPRERLEVVLEAAREVRR 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 450 AVIASTLTTIVVFLPIVYLHGASGELFKDQAWTVTFSLVSSLFVAILVIPMLYTQLSGKKVKMEEVKSIR--ITRYSKIL 527
Cdd:COG3696 443 PIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKENPLVRwlKRLYRPLL 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 528 RKLVRHRWWVIGMAVLLLVVTGLLTPFIGTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDLLYTI--VGgdslcT 605
Cdd:COG3696 523 RWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFpeVE-----S 597
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 606 IYSHVGEG-SGSENA-IFEGENTAMMKiilfPE----CILSPENVIARFLEEAKNPDGLELSIRQ------DEnslssLL 673
Cdd:COG3696 598 VVSRTGRAeDATDPMgVNMSETFVILK----PRsewrSGRTKEELIAEMREALEQIPGVNFNFSQpiqmrvDE-----LL 668
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 674 GSEGAPIVVEVKGEELDEIAKITGEVKERMQEVDGVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGK 753
Cdd:COG3696 669 SGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGK 748
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 754 EAGKMeYRGEMR-DIVIKVPD---ISLGALGSLVIRSGTQEFL-LDEIASITHGQAPKEILRRNQSRIGKIMANMDtGKS 828
Cdd:COG3696 749 AVGQV-YEGERRfDIVVRLPEelrDDPEAIRNLPIPTPSGAQVpLSQVADIEVVEGPNQISRENGRRRIVVQANVR-GRD 826
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 829 LDKVAAEVRLAV-KDIDLPANYSITVTGEEEKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAI 907
Cdd:COG3696 827 LGSFVAEAQAKVaEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGV 906
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 908 LLFFITGTTINMMGVIGIVMLGGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFG 987
Cdd:COG3696 907 LALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTG 986
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|.
gi 491930720 988 EGASLRSPMAIAVIGGLITSTLMSLMVIPCVYYVLEKIKRR 1028
Cdd:COG3696 987 PGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLR 1027
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
12-1024 |
1.94e-151 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 476.43 E-value: 1.94e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 12 PVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQFVKNMESMAIRQSDVTQVSSVIKAGTAR 91
Cdd:NF033617 8 PVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYST 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 92 ITVEYTWTKDMDEAFLDLQKAMNPfAQNKEITELK--ITQHDANLS--PVVLVG-----MSHQNITDMAELRriaesyIR 162
Cdd:NF033617 88 ITLQFRLGTDLDVALSEVQAAINA-AQSLLPSEAPdpPVYRKANSAdtPIMYIGltseeMPRGQLTDYAERV------LA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 163 NELIRLEGVAEVTLSGEEVTTLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSELGLQYLVKSSSLFSTEADFEN 242
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYED 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 243 LIVGYKPvqqetsgnsssetvtdlNKAPVFLKEVATVQFVNARPENIVRINGKRSIGLSIYKEMRFNTVKVVDEVTSRLA 322
Cdd:NF033617 241 LVIKYAD-----------------NGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLP 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 323 VIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNLMFFNGLTLN 401
Cdd:NF033617 304 ELQETLPkNIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSIN 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 402 IMTLGGLALGAGMLVDNAIVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGASGELFKDQAW 481
Cdd:NF033617 384 LLTLMALVLAIGLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAV 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 482 TVTFSLVSSLFVAILVIPMLYTQLSGKKVK-------MEEVKSIRITRYSKILRKLVRHRWWVIGMAVLLLVVTGLLTPF 554
Cdd:NF033617 464 TLAGAVIISGIVALTLTPMMCSRLLKANEKpgrfaraVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVF 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 555 IGTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDLLYTIVGGDSLcTIYSHVGEGSGSenaifegeNTAMMKIILF 634
Cdd:NF033617 544 IPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSL-TSFNGVGGNPGD--------NTGFGIINLK 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 635 P--ECILSPENVIARFLEEAKNPDGLELSIRQdensLSSLLGSEG---APIVVEVKGEELDEIAKITGEVKERMQEVDGV 709
Cdd:NF033617 615 PwdERDVSAQEIIDRLRPKLAKVPGMDLFLFP----LQDLPGGAGsslPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQF 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 710 YDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEAGKMEYRGEMRDIVIKV---PDISLGALGSLVIRS 786
Cdd:NF033617 691 ADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVdrrYRLNPEALNQIYVRS 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 787 GTQEFL-LDEIASITHGQAPKEILRRNQSRIGKIMANMDTGKSLDKVAAEVRLAVKDIdLPANYSITVTGEEEKRQESMH 865
Cdd:NF033617 771 NDGKLVpLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGS 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 866 SLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSIILVDRINQ 945
Cdd:NF033617 850 SLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANE 929
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 946 LS-QAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRSPMAIAVIGGLITSTLMSLMVIPCVYYVLEK 1024
Cdd:NF033617 930 LQrHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
4-1021 |
8.22e-114 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 376.79 E-value: 8.22e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 4 IVKFAVGNPVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQF-------------VKNMES 70
Cdd:TIGR00914 5 IISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVtypietamaglpgLETTRS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 71 MAirQSDVTQVSSVIKAGT----ARITVEYTWTKDMDEAFLDLQKAMNPFAQN-KEITELKITQHDAnlspvvlVGMSHQ 145
Cdd:TIGR00914 85 LS--RYGLSQVTVIFKDGTdlyfARQLVNERLQQARDNLPEGVSPEMGPISTGlGEIFLYTVEAEEG-------ARKKDG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 146 NITDMAELRRIAESYIRNELIRLEGVAEVTLSGEEVTTLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSELGLQ 225
Cdd:TIGR00914 156 GAYTLTDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQ 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 226 YLVKSSSLFSTEADFENLIVGykpvqqetsgnsSSETVtdlnkaPVFLKEVATVQFVNARPENIVRINGKRSIGLSIYKE 305
Cdd:TIGR00914 236 YLVRAPGQVQSMDDIRNIVIA------------TGEGV------PIRIRDVARVQIGKELRTGAATENGKEVVLGTVFML 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 306 MRFNTVKVVDEVTSRLAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPI 384
Cdd:TIGR00914 298 IGENSRTVAQAVGDKLETINKTLPeGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPL 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 385 SIVATFNLMFFNGLTLNIMTLGGLALGAgmLVDNAIVVIESIFRNQE-------KGVSVKE---AVVTGTAEVANAVIAS 454
Cdd:TIGR00914 378 SLLITFIGMVFQGISANLMSLGALDFGL--IVDGAVVIVENAHRRLAeaqhhhgRQLTLKErlhEVFAASREVRRPLIFG 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 455 TLTTIVVFLPIVYLHGASGELFKDQAWTVTFSLVSSLFVAILVIPMLYTQLSGKKVKMEEVKSIRIT--RYSKILRKLVR 532
Cdd:TIGR00914 456 QLIITLVFLPIFTLTGVEGKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVLkrRYEPLLERVLA 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 533 HRWWVIGMAVLLLVVTGLLTPFIGTEFMPR-AESKAFTAVVKMPeGTQMERTAAAVGNLEDLLYTIvggDSLCTIYSHVG 611
Cdd:TIGR00914 536 WPAVVLGAAAVSIVLVVWIASRVGGEFIPSlNEGDLAYQALRIP-GTSLAQSVAMQQTLEKLIKSF---PEVARVFAKTG 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 612 EGSGSENAIfeGENTAMMKIIL-----FPECILSPENVIARFLEEAKNPDGLELSIRQD-ENSLSSLLGSEGAPIVVEVK 685
Cdd:TIGR00914 612 TAEIATDPM--PPNASDTYIILkpesqWPEGKKTKEDLIEEIQEATVRIPGNNYEFTQPiQMRFNELISGVRSDVAVKVF 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 686 GEELDEIAKITGEVKERMQEVDGVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEAGKMeYRGEMR 765
Cdd:TIGR00914 690 GDDLDDLDATAEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGET-FEGDRR 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 766 -DIVIKVPDI---SLGALGSLVI-----RSGTQEFL-LDEIASITHGQAPKEILRRNQSRIGKIMANM---DTGKSLDKV 832
Cdd:TIGR00914 769 fDIVIRLPESlreSPQALRQLPIplplsEDARKQFIpLSDVADLRVSPGPNQISRENGKRRVVVSANVrgrDLGSFVDDA 848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 833 AAEVRLAVKdidLPANYSITVTGEEEKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFI 912
Cdd:TIGR00914 849 KKAIAEQVK---LPPGYWITWGGQFEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWL 925
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 913 TGTTINMMGVIGIVMLGGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASL 992
Cdd:TIGR00914 926 RGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEV 1005
|
1050 1060
....*....|....*....|....*....
gi 491930720 993 RSPMAIAVIGGLITSTLMSLMVIPCVYYV 1021
Cdd:TIGR00914 1006 QRPLATVVIGGIITATLLTLFVLPALYRL 1034
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
4-1032 |
7.79e-97 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 330.15 E-value: 7.79e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 4 IVKFAVGNPVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELK--------VGERPPEEIEKQF--VKNMESMAi 73
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASypgasaqtVQDTVTQVIEQNMngIDGLRYMS- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 74 rqsdvtqvSSVIKAGTARITVEYTWTKDMDEAFLD----LQKAMNPFAQNKEITELKITQHDANLSPVVLVgMSHQNITD 149
Cdd:TIGR00915 80 --------SSSDSDGSMTITLTFEQGTDPDIAQVQvqnkLQLATPLLPQEVQRQGVRVEKASSNFLMVIGL-VSDDGSMT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 150 MAELRRIAESYIRNELIRLEGVAEVTLSGEEVTtLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSEL------G 223
Cdd:TIGR00915 151 KEDLSDYAASNMVDPLSRLEGVGDVQLFGSQYA-MRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLpavpgqQ 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 224 LQYLVKSSSLFSTEADFENLIVgykpvqqeTSGNSSSEtvtdlnkapVFLKEVATVQFVNARPENIVRINGKRSIGLSIY 303
Cdd:TIGR00915 230 LNATIIAQTRLQTPEQFENILL--------KVNTDGSQ---------VRLKDVARVELGGENYSISARFNGKPASGLAIK 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 304 KEMRFNTVKVVDEVTSRLAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSI 382
Cdd:TIGR00915 293 LATGANALDTAKAVKAELAVLEPFFPqGMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAV 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 383 PISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFR-NQEKGVSVKEAVVTGTAEVANAVIASTLTTIVV 461
Cdd:TIGR00915 373 PVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLVDDAIVVVENVERvMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAV 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 462 FLPIVYLHGASGELFKDQAWTVTFSLVSSLFVAILVIPMLYTQL--SGKKVKMEEVKS-----------IRITRYSKILR 528
Cdd:TIGR00915 453 FVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMlkPIEKGEHHEKKGgffgwfnrmfdSSTHGYENGVG 532
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 529 KLVRHRWWVIGMAVLLLVVTGLLTPFIGTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDLLYTiVGGDSLCTIYS 608
Cdd:TIGR00915 533 KILRRRGRYLLVYVLLVGGMVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLA-KEKANVESVFT 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 609 HVGEG-SGSenaifeGENTAMMKIILFP-ECILSPEN----VIAR-FLEEAKNPDGLELSIrqDENSLSSLLGSEGAPIV 681
Cdd:TIGR00915 612 VNGFSfAGR------GQNMGMAFIRLKDwEERTGKENsvfaIAGRaTGHFMQIKDAMVIAF--VPPAILELGNATGFDFF 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 682 VEVK-GEELDEIAKITGEVKERMQEVDGVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEAGKMEY 760
Cdd:TIGR00915 684 LQDRaGLGHEALLQARNQLLGLAAQNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFID 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 761 RGEMRDIVIKVPD---ISLGALGSLVIRSGTQEFL-LDEIASITHGQAPKEILRRNQSRIGKIMANMDTGKSLDKVAAEV 836
Cdd:TIGR00915 764 RGRVKRVYVQAEEdarMSPEDINKWYVRNASGEMVpFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAM 843
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 837 RLAVKdiDLPANYSITVTGE--EEKRQESMHSLLFAllLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFITG 914
Cdd:TIGR00915 844 EAIAQ--KLPPGFGFSWTGMsyEERLSGSQAPALYA--LSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRG 919
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 915 TTINMMGVIGIVMLGGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRS 994
Cdd:TIGR00915 920 LSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQH 999
|
1050 1060 1070
....*....|....*....|....*....|....*...
gi 491930720 995 PMAIAVIGGLITSTLMSLMVIPCVYYVLEKIKRRINHR 1032
Cdd:TIGR00915 1000 AIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHE 1037
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
12-1036 |
1.70e-93 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 320.52 E-value: 1.70e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 12 PVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQFVKNMESMAIRQSDVTQVSSVIKAGTAR 91
Cdd:PRK10614 11 PVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 92 ITVEYTWTKDMDEAFLDLQKAMNPfAQNKEITEL--KITQHDANLS--PVVLVGMSHQNITDmAELRRIAESYIRNELIR 167
Cdd:PRK10614 91 IILQFDFDRDINGAARDVQAAINA-AQSLLPSGMpsRPTYRKANPSdaPIMILTLTSDTYSQ-GQLYDFASTQLAQTISQ 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 168 LEGVAEVTLSGEEVTTLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSELGLQYLVKSSSLFSTEADFENLIVGY 247
Cdd:PRK10614 169 IDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLIIHY 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 248 KpvqqetsgnsssetvtdlNKAPVFLKEVATVQFVNARPENIVRINGKRSIGLSIYKEMRFNTVKVVDEVTSRLAVIEDA 327
Cdd:PRK10614 249 N------------------NGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRET 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 328 LP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNLMFFNGLTLNIMTLG 406
Cdd:PRK10614 311 IPaAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLM 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 407 GLALGAGMLVDNAIVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGASGELFKDQAWTVTFS 486
Cdd:PRK10614 391 ALTIATGFVVDDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVA 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 487 LVSSLFVAILVIPMLYTQLSgKKVKMEEVKSIR-ITR--------YSKILRKLVRHRWWVIGMAVLLLVVTGLLTPFIGT 557
Cdd:PRK10614 471 IGISLLVSLTLTPMMCAWLL-KSSKPREQKRLRgFGRmlvalqqgYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 558 EFMPRAESKAFTAVVKMPEGTQMErtaAAVGNLEDLLyTIVGGDSlcTIYSHVGEGSGSENaifegeNTAMMKIILFP-- 635
Cdd:PRK10614 550 TFFPEQDTGRLMGFIQADQSISFQ---AMRGKLQDFM-KIIRDDP--AVDNVTGFTGGSRV------NSGMMFITLKPls 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 636 ECILSPENVIARFLEEAKNPDGLELSI----------RQDENSLSSLLGSegapivvevkgEELDEIAKITGEVKERMQE 705
Cdd:PRK10614 618 ERSETAQQVIDRLRVKLAKEPGANLFLmavqdirvggRQSNASYQYTLLS-----------DDLAALREWEPKIRKALAA 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 706 VDGVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQL-----KQQLSGKEAGKMEYRGEMRDIVIKVPDISlgALG 780
Cdd:PRK10614 687 LPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLnnafgQRQISTIYQPLNQYKVVMEVDPRYTQDIS--ALE 764
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 781 SL-VIRSGTQEFLLDEIASITHGQAPKEILRRNQSRIGKIMANMDTGKSLDKVAAEVRLAVKDIDLPANYSITVTGEEEK 859
Cdd:PRK10614 765 KMfVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIERAMTQLGVPSTVRGSFAGTAQV 844
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 860 RQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSIIL 939
Cdd:PRK10614 845 FQETMNSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMM 924
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 940 VD-RINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRSPMAIAVIGGLITSTLMSLMVIPCV 1018
Cdd:PRK10614 925 VDfALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPVV 1004
|
1050
....*....|....*...
gi 491930720 1019 YYVLEKIKRRINHRTKKS 1036
Cdd:PRK10614 1005 YLFFDRLRLRFSRKPKQT 1022
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
12-1035 |
4.17e-81 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 285.86 E-value: 4.17e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 12 PVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRL-FIELKVGERP-------PEEIEKQFVKnmesmairQSDVTQVSS 83
Cdd:PRK10503 20 PVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIqVVTLYPGASPdvmtsavTAPLERQFGQ--------MSGLKQMSS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 84 VIKAGTARITVEYTWTKDMDEAFLDLQKAMNPfAQNKEITELKITQHDANLSP---------VVLVGMSHQNITDMAELR 154
Cdd:PRK10503 92 QSSGGASVITLQFQLTLPLDVAEQEVQAAINA-ATNLLPSDLPNPPVYSKVNPadppimtlaVTSTAMPMTQVEDMVETR 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 155 riaesyIRNELIRLEGVAEVTLSGEEVTTLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSELGLQYLVKSSSLF 234
Cdd:PRK10503 171 ------VAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 235 STEADFENLIVGYKpvqqetsgnsssetvtdlNKAPVFLKEVATVQfvnARPENI---VRINGKRSIGLSIYKEMRFNTV 311
Cdd:PRK10503 245 QSAEEYRQLIIAYQ------------------NGAPIRLGDVATVE---QGAENSwlgAWANKQQAIVMNVQRQPGANII 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 312 KVVDEVTSRLAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATF 390
Cdd:PRK10503 304 ATADSIRQMLPQLTESLPkSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTF 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 391 NLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHG 470
Cdd:PRK10503 384 AVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGD 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 471 ASGELFKDQAWTVTFSLVSSLFVAILVIPMLYTQL----SGKKVKMEEVKSIR-----ITRYSKILRKLVRHRWWVIGMA 541
Cdd:PRK10503 464 IVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMlsqeSLRKQNRFSRASERmfdrvIAAYGRGLAKVLNHPWLTLSVA 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 542 VLLLVVTGLLTPFIGTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDLLYTIVGGDSLCtiySHVGEgSGSENAIf 621
Cdd:PRK10503 544 LSTLLLTVLLWIFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLT---SFVGV-DGTNPSL- 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 622 egeNTAMMKIILFPeciLSPEN-----VIARFLEEAKNPDGLELSIrQDENSLSSLLGSEGAPIVVEVKGEELDEIAKIT 696
Cdd:PRK10503 619 ---NSARLQINLKP---LDERDdrvqkVIARLQTAVAKVPGVDLYL-QPTQDLTIDTQVSRTQYQFTLQATSLDALSTWV 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 697 GEVKERMQEVDGVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQL----KQQL-SGKEAGKMEYRGEMRDIVIKV 771
Cdd:PRK10503 692 PKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALynafGQRLiSTIYTQANQYRVVLEHNTENT 771
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 772 PdiSLGALGSLVIRSGTQEFL-LDEIASITHGQAPKEILRRNQSRIGKIMANMDTGKSLDKVAAEVRLAVKDIDLPANYS 850
Cdd:PRK10503 772 P--GLAALDTIRLTSSDGGVVpLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADIT 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 851 ITVTGEEEKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFITGTTINMMGVIGIVMLGG 930
Cdd:PRK10503 850 TQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIG 929
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 931 IAVNNSIILVD-RINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRSPMAIAVIGGLITSTL 1009
Cdd:PRK10503 930 IVKKNAIMMIDfALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQV 1009
|
1050 1060
....*....|....*....|....*.
gi 491930720 1010 MSLMVIPCVYYVLEKIKRRINHRTKK 1035
Cdd:PRK10503 1010 LTLFTTPVIYLLFDRLALYTKSRFPR 1035
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
6-1028 |
3.83e-73 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 262.84 E-value: 3.83e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 6 KFAVGNPVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQFVKNMESMAIRQSDVTQVSSVI 85
Cdd:PRK10555 3 NFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 86 KA-GTARITVEYTWTKDMDEAFLD----LQKAMNPFAQNKEITELKITQH-DANLSPVVLVG----MSHQNITDMAElrr 155
Cdd:PRK10555 83 SGtGQASVTLSFKAGTDPDEAVQQvqnqLQSAMRKLPQAVQNQGVTVRKTgDTNILTIAFVStdgsMDKQDIADYVA--- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 156 iaeSYIRNELIRLEGVAEVTLSGEEVTtLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSEL------GLQYLVK 229
Cdd:PRK10555 160 ---SNIQDPLSRVNGVGDIDAYGSQYS-MRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTpsvdkqALNATIN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 230 SSSLFSTEADFENLIVgykPVQQETSgnsssetvtdlnkaPVFLKEVATVQFVNARPENIVRINGKRSIGLSIYKEMRFN 309
Cdd:PRK10555 236 AQSLLQTPEQFRDITL---RVNQDGS--------------EVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGAN 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 310 TVKVVDEVTSRLAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVA 388
Cdd:PRK10555 299 EMATAKLVLNRLDELAQYFPhGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMG 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 389 TFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFR-NQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVY 467
Cdd:PRK10555 379 TFSVLYAFGYSINTLTMFAMVLAIGLLVDDAIVVVENVERiMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAF 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 468 LHGASGELFKDQAWTVTFSLVSSLFVAILVIPMLYTQLSgKKVKMEEVKSIR-------------ITRYSKILRKLVRH- 533
Cdd:PRK10555 459 FGGTTGAIYRQFSITIVSAMVLSVLVAMILTPALCATLL-KPLKKGEHHGQKgffgwfnrmfnrnAERYEKGVAKILHRs 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 534 -RWWVIGMAVLLLVVTGLLTpfIGTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDLLYTiVGGDSLCTIYSHVGE 612
Cdd:PRK10555 538 lRWILIYVLLLGGMVFLFLR--LPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFT-HEKDNVMSVFATVGS 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 613 GSGSenaifEGENTAMMKIILFPECILSPEN-----VIARF------LEEAKnpdglelSIRQDENSLSSLLGSEGAPIV 681
Cdd:PRK10555 615 GPGG-----NGQNVARMFIRLKDWDERDSKTgtsfaIIERAtkafnkIKEAR-------VIASSPPAISGLGSSAGFDME 682
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 682 VEVK-GEELDEIAKITGEVKERMQEVDGVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEAGKMEY 760
Cdd:PRK10555 683 LQDHaGAGHDALMAARNQLLALAAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMD 762
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 761 RGEMRDIVIK-------VP-DISLgalgsLVIRSGTQEFLLDEIASITHGQAPKEILRRNQSR-----IGKIMANMDTGK 827
Cdd:PRK10555 763 RGRVKKVYVQaaapyrmLPdDINL-----WYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYsaveiVGEAAPGVSTGT 837
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 828 SLDKVAAEVRlavkdiDLPANYSITVTGE--EEKRQESMHSLLFAllLSVVLVYMVMASQFESLLHPFTILLTIPLAVVG 905
Cdd:PRK10555 838 AMDIMESLVK------QLPNGFGLEWTAMsyQERLSGAQAPALYA--ISLLVVFLCLAALYESWSVPFSVMLVVPLGVIG 909
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 906 AILLFFITGTTINMMGVIGIVMLGGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFG 985
Cdd:PRK10555 910 ALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATS 989
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|...
gi 491930720 986 FGEGASLRSPMAIAVIGGLITSTLMSLMVIPcVYYVLekIKRR 1028
Cdd:PRK10555 990 TGAGSGSQHAVGTGVMGGMISATILAIFFVP-LFFVL--VRRR 1029
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
6-1032 |
8.54e-71 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 255.93 E-value: 8.54e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 6 KFAVGNPVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQFVKNMESMAIRQSDVTQVSSVI 85
Cdd:PRK09577 3 RFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 86 KAGTARITVEYTWTKDMDEAFLDLQKAMNPF-AQNKEITE---LKITQHDANLSPVVLVGMSHQNITDMaELRRIAESYI 161
Cdd:PRK09577 83 SAGQASLSLTFKQGVNADLAAVEVQNRLKTVeARLPEPVRrdgIQVEKAADNIQLIVSLTSDDGRLTGV-ELGEYASANV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 162 RNELIRLEGVAEVTLSGEEVTtLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSELG------LQYLVKSSSLFS 235
Cdd:PRK09577 162 LQALRRVEGVGKVQFWGAEYA-MRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAvpdsapIAATVFADAPLK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 236 TEADFENLivgykPVQQETSGNSssetvtdlnkapVFLKEVATVQFVNARPENIVRINGKRSIGLSIYKEMRFNTVKVVD 315
Cdd:PRK09577 241 TPEDFGAI-----ALRARADGSA------------LYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEK 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 316 EVTSRLAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNLMF 394
Cdd:PRK09577 304 RVRATMDELSRYFPpGVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVML 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 395 FNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFR-NQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGASG 473
Cdd:PRK09577 384 AAGFSINVLTMFGMVLAIGILVDDAIVVVENVERlMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVG 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 474 ELFKDQAWTVTFSLVSSLFVAILVIPMLYTQLSGKKVKMEEVKS----------IRIT-----RYSKILRKLVrhRWWVI 538
Cdd:PRK09577 464 NIYRQFALSLAVSIGFSAFLALSLTPALCATLLKPVDGDHHEKRgffgwfnrfvARSTqryatRVGAILKRPL--RWLVV 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 539 -GMAVLLLVVTGLLTPfigTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDLL-------YTI-VGGdslctiYSH 609
Cdd:PRK09577 542 yGALTAAAALLFTRLP---TAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLrrhepvaYTFaLGG------FNL 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 610 VGEGSGSeNAIF---------EGENTAMMKIIlfpecilspENVIARFleeAKNPDGLELSIrqDENSLSSLLGSEGAPI 680
Cdd:PRK09577 613 YGEGPNG-GMIFvtlkdwkerKAARDHVQAIV---------ARINERF---AGTPNTTVFAM--NSPALPDLGSTSGFDF 677
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 681 VVEVKGE-ELDEIAKITGEVKERMQEVDGVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEAGKME 759
Cdd:PRK09577 678 RLQDRGGlGYAAFVAAREQLLAEGAKDPALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFM 757
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 760 YRGEMRDIVIKVPD---ISLGALGSLVIRSGTQEFL-LDEIASITHGQAPKEILRRNQSRIGKIMANMDTGKSLDKVAAE 835
Cdd:PRK09577 758 HGSQVRRVIVQADGrhrLDPDDVKKLRVRNAQGEMVpLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAA 837
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 836 V-RLAVKdidLPANYSITVTGE--EEKRQESMHSLLFAllLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILlffi 912
Cdd:PRK09577 838 IeRIAAT---LPAGIGYAWSGQsfEERLSGAQAPMLFA--LSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVL---- 908
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 913 tGTTINMMG-----VIGIVMLGGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFG 987
Cdd:PRK09577 909 -GVTLRGMPndiyfKVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASG 987
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*
gi 491930720 988 EGASLRSPMAIAVIGGLITSTLMSLMVIPCVYYVLEKIKRRINHR 1032
Cdd:PRK09577 988 AASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRLFDVGPRR 1032
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
12-1024 |
4.91e-68 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 247.44 E-value: 4.91e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 12 PVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQFVKNMESMAIRQSDVTQVSSVIKAGTAR 91
Cdd:PRK09579 11 PVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 92 ITVEYTWTKDMDEAFLDLQKAMNPFAQN--KEITELKITQHDANLSPVVLVG-----MSHQNITDMaeLRRIaesyIRNE 164
Cdd:PRK09579 91 ISIYARIGADSDRLFTELLAKANEVKNQlpQDAEDPVLSKEAADASALMYISfyseeMSNPQITDY--LSRV----IQPK 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 165 LIRLEGVAEVTLSGEEVTTLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGRVSElglQYLVKS----SSLFSTEAdf 240
Cdd:PRK09579 165 LATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKG---EYVVTSinasTELKSAEA-- 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 241 enlivgYKPVQQETSGNSSsetvtdlnkapVFLKEVATVQFVNARPENIVRINGKRSIGLSIYKEMRFNTVKVVDEVTSR 320
Cdd:PRK09579 240 ------FAAIPVKTSGDSR-----------VLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 321 LAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNLMFFNGLT 399
Cdd:PRK09579 303 MPELESQLPpNLKVSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYS 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 400 LNIMTLGGLALGAGMLVDNAIVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGASGELFKDQ 479
Cdd:PRK09579 383 INLLTLLAMVLAIGLVVDDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEF 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 480 AWTVTFSLVSSLFVAILVIPMLYTQL-------SGKKVKMEEVKSIRITRYSKILRKLVRHRWWVIGMAVLLLVVTGLLT 552
Cdd:PRK09579 463 ALTLAGAVIISGIVALTLSPMMCALLlrheenpSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLL 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 553 PFIGTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDLLYTIVGGDSLCTIYSHVGEGSGSENAIF----EGENTAM 628
Cdd:PRK09579 543 KFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQSGIGGFLLkpwnERERTQM 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 629 MkiiLFPECILSPENViarfleeaknpDGLELSirqdENSLSSLLGS-EGAP--IVVEVKGeELDEIAKITGEVKERMQE 705
Cdd:PRK09579 623 E---LLPLVQAKLEEI-----------PGLQIF----GFNLPSLPGTgEGLPfqFVINTAN-DYESLLQVAQRVKQRAQE 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 706 VDGVYDVVTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEAGKMEYRGEMRDIVIKVPDI---SLGALGSL 782
Cdd:PRK09579 684 SGKFAFLDIDLAFDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPyrdNPGWLNNY 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 783 VIRSGTQEFL-LDEIASITHGQAPKEILRRNQ--SRIGKIMANMDTGKSLDKVAAEVRLavkdiDLPANYSITVTGEEEK 859
Cdd:PRK09579 764 YVKNEQGQLLpLSTLITLSDRARPRQLNQFQQlnSAIISGFPIVSMGEAIETVQQIARE-----EAPEGFAFDYAGASRQ 838
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 860 RQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSIIL 939
Cdd:PRK09579 839 YVQEGSALWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILI 918
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 940 VDRINQL-SQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRSPMAIAVIGGLITSTLMSLMVIPCV 1018
Cdd:PRK09579 919 VEFANQLrHEQGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCI 998
|
....*.
gi 491930720 1019 YYVLEK 1024
Cdd:PRK09579 999 YTLLAK 1004
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
6-1034 |
5.72e-60 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 223.63 E-value: 5.72e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 6 KFAVGNPVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQFVKNME-SMAIRQSDVTQVSSV 84
Cdd:PRK15127 3 NFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEqNMNGIDNLMYMSSNS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 85 IKAGTARITVEYTWTKDMDEAFLD----LQKAMNPFAQnkEITELKITQHDANLSPVVLVG-------MSHQNITDMAEl 153
Cdd:PRK15127 83 DSTGTVQITLTFESGTDADIAQVQvqnkLQLAMPLLPQ--EVQQQGVSVEKSSSSFLMVVGvintdgtMTQEDISDYVA- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 154 rriaeSYIRNELIRLEGVAEVTLSGEEVTtLTVQTDPYKLNAFQLKIEDIASRIESNNQSISGGrvsELGLQYLVKSSSL 233
Cdd:PRK15127 160 -----ANMKDPISRTSGVGDVQLFGSQYA-MRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAG---QLGGTPPVKGQQL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 234 FSTeadfenLIVGYKPVQQETSGNSSSETVTDLNKapVFLKEVATVQFVNARPENIVRINGKRSIGLSIYKEMRFNTVKV 313
Cdd:PRK15127 231 NAS------IIAQTRLTSTEEFGKILLKVNQDGSR--VRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDT 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 314 VDEVTSRLAVIEDALP-GYHFQVISNQGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNL 392
Cdd:PRK15127 303 AAAIRAELAKMEPFFPsGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAV 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 393 MFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFR-NQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGA 471
Cdd:PRK15127 383 LAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERvMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGS 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 472 SGELFKDQAWTVTFSLVSSLFVAILVIPMLYTQL--------SGKKVK--------MEEVKSIRIT-RYSKILRK----L 530
Cdd:PRK15127 463 TGAIYRQFSITIVSAMALSVLVALILTPALCATMlkpiakgdHGEGKKgffgwfnrMFEKSTHHYTdSVGNILRStgryL 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 531 VRHRWWVIGMAVLLLVvtglltpfIGTEFMPRAESKAFTAVVKMPEGTQMERTAAAVGNLEDlLYTIVGGDSLCTIYSHV 610
Cdd:PRK15127 543 VLYLIIVVGMAYLFVR--------LPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTD-YYLTKEKNNVESVFAVN 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 611 GEGSGSenaifEGENTAMmkiilfpeCILSPENVIARFLEEAKNPDGLELSIRQDENSLSSLLGSEGAPIVVEV---KGE 687
Cdd:PRK15127 614 GFGFAG-----RGQNTGI--------AFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELgtaTGF 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 688 ELDEI-------AKITGEVKERMQEVDGVYDVVTSI-----EDgAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEA 755
Cdd:PRK15127 681 DFELIdqaglghEKLTQARNQLLGEAAKHPDMLVGVrpnglED-TPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYV 759
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 756 GKMEYRGEMRDIVIK-------VPDislgALGSLVIRSGTQEFLLDEIASITHGQAPKEILRR-NQSRIGKIMANMDTGK 827
Cdd:PRK15127 760 NDFIDRGRVKKVYVMseakyrmLPD----DIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERyNGLPSMEILGQAAPGK 835
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 828 SLDKVAAEV-RLAVKdidLPA--NYSITVTGEEEKRQESMHSLLFAllLSVVLVYMVMASQFESLLHPFTILLTIPLAVV 904
Cdd:PRK15127 836 STGEAMELMeELASK---LPTgvGYDWTGMSYQERLSGNQAPALYA--ISLIVVFLCLAALYESWSIPFSVMLVVPLGVI 910
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 905 GAILLFFITGTTINMMGVIGIVMLGGIAVNNSIILVDRINQL-SQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMT 983
Cdd:PRK15127 911 GALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLmDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLV 990
|
1050 1060 1070 1080 1090
....*....|....*....|....*....|....*....|....*....|.
gi 491930720 984 FGFGEGASLRSPMAIAVIGGLITSTLMSLMVIPcVYYVLekIKRRINHRTK 1034
Cdd:PRK15127 991 ISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVP-VFFVV--VRRRFSRKNE 1038
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
309-1028 |
2.51e-27 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 119.58 E-value: 2.51e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 309 NTVKVVDEVTSRLAVIEDalPGYHFQVISN---QGTFIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPIS 385
Cdd:COG1033 178 DRKEVVAEIRAIIAKYED--PGVEVYLTGFpvlRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLA 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 386 IVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPI 465
Cdd:COG1033 256 VIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 466 VYlhgASGELFKDQAWTVTFSLVSSLFVAILVIPMLYTQLSGKKVKMEEVKSIRitRYSKILRKL----VRHRWWVIGMA 541
Cdd:COG1033 336 LF---SDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPP--ELGRLLAKLarfvLRRPKVILVVA 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 542 VLLLVVTGLLTPFIGTEFMPRAEskaftavvkMPEGTQMERTAAAVgnledllytivggdslctiyshvgegsgseNAIF 621
Cdd:COG1033 411 LVLAVVSLYGISRLKVEYDFEDY---------LPEDSPIRQDLDFI------------------------------EENF 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 622 EGENTamMKIILfpecilspenviarfleEAKNPDGlelsIRQDENslssllgsegapivvevkgeeLDEIAkitgEVKE 701
Cdd:COG1033 452 GGSDP--LEVVV-----------------DTGEPDG----LKDPEV---------------------LKEID----RLQD 483
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 702 RMQEVDGVYDVvtsiedgapevvisidrtiaginnLSVATVIEQLKQQLSGkeaGKMEYRGemrdivikVPDISLGALGS 781
Cdd:COG1033 484 YLESLPEVGKV------------------------LSLADLVKELNQALNE---GDPKYYA--------LPESRELLAQL 528
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 782 LVIRSGTQEFLLDEIASITHGQAPkeilrrnqsrigkIMANMDTGKS--LDKVAAEVRLAVKDIDLPANYSITVTGE--- 856
Cdd:COG1033 529 LLLLSSPPGDDLSRFVDEDYSAAR-------------VTVRLKDLDSeeIKALVEEVRAFLAENFPPDGVEVTLTGSavl 595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 857 -EEKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTI--PLAVVGAILLFFitGTTINMMGVIGIVMLGGIAV 933
Cdd:COG1033 596 fAAINESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLIPNllPILLTFGLMGLL--GIPLNIATAVVASIALGIGV 673
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 934 NNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFgfgegASLR--SPMAIAVIGGLITSTLMS 1011
Cdd:COG1033 674 DYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLF-----SSFPplADFGLLLALGLLVALLAA 748
|
730
....*....|....*..
gi 491930720 1012 LMVIPCVYYVLEKIKRR 1028
Cdd:COG1033 749 LLLLPALLLLLDPRIAK 765
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
2-512 |
1.28e-26 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 117.90 E-value: 1.28e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 2 KNIVKFAVGNPVTICMIVFALLLLGKVSYDQLSVDLLPDLNNPRLFIELKVGERPPEEIEKQFVKNMESMAIRQSDVTQV 81
Cdd:COG0841 516 GRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESV 595
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 82 SSVIKAG-------TARITVEytwTKDMDEAFLD----LQKAMNPFAQNKEITELKITQHDANLSP-----VVLVGmshq 145
Cdd:COG0841 596 FSVVGFSgggsgsnSGTIFVT---LKPWDERDRSadeiIARLREKLAKIPGARVFVFQPPAGGLGSgapieVQLQG---- 668
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 146 niTDMAELRRIAESyIRNELIRLEGVAEVTLSGEEVT-TLTVQTDPYKLNAFQLKIEDIASRIesnNQSISGGRVSEL-- 222
Cdd:COG0841 669 --DDLEELAAAAEK-LLAALRQIPGLVDVRSDLQLGKpELQLDIDREKAAALGVTVADVASTL---RAALGGRYVNDFnr 742
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 223 -GLQYLVK---SSSLFSTEADFENLIVgykpvqqeTSGNSssetvtdlnkAPVFLKEVATVQFVNArPENIVRINGKRSI 298
Cdd:COG0841 743 gGREYDVRvqaPEEDRNSPEDLENLYV--------RTPDG----------EMVPLSSVATIEEGTG-PSSINRYNGQRSV 803
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 299 GLSIYKEMRFNTVKVVDEVTSRLAviEDALP-GYHFQVISNQGTFIKSAigevkSSAILGIVLAVIVLFVFL----RRMG 373
Cdd:COG0841 804 TVSANLAPGVSLGEALAAIEELAA--ELKLPpGVSIEFTGQAEEEQESF-----SSLGLAFLLALLLVYLVLaaqfESFI 876
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 374 TTLIVSLSIPISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIA 453
Cdd:COG0841 877 QPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLRLRPILM 956
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 491930720 454 STLTTIVVFLPIVYLHGASGELFKDQAWTVTFSLVSSLFVAILVIPMLYTQLSGKKVKM 512
Cdd:COG0841 957 TSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRRL 1015
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
698-1032 |
1.19e-17 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 88.51 E-value: 1.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 698 EVKERMQEVDGVYDVvTSIEDGAPEVVISIDRTIAGINNLSVATVIEQLKQQLSGKEAGKMEYRGEMRDIVIKVPDISLG 777
Cdd:pfam00873 160 NIKPQLSRVPGVGDV-QLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 778 ALGSLVIRSGT-QEFLLDEIASITHGQAPKEIL-RRNQSRIGKIMANMDTGKSLDKVAAEVRLAVKDID--LPANYSITV 853
Cdd:pfam00873 239 DFEKIIVKNQDgSPVRLRDVATVELGSELYRGFaTFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKptFPQGVEIVV 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 854 TGEE-EKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIA 932
Cdd:pfam00873 319 VYDTtPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLV 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 933 VNNSIILVDRINQ-LSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPM-TFGFGEGASLRsPMAIAVIGGLITSTLM 1010
Cdd:pfam00873 399 VDDAIVVVENIERvLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPIlFLGGLTGRIFR-QFAITIVLAILLSVLV 477
|
330 340
....*....|....*....|..
gi 491930720 1011 SLMVIPCVYYVLEKIKRRINHR 1032
Cdd:pfam00873 478 ALTLTPALCATLLKPRREPKHG 499
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
148-514 |
1.93e-15 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 81.35 E-value: 1.93e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 148 TDMAELRRIAESyIRNELIRLEGVAEVTLsgEEVT---TLTVQTDPYKLNAFQLKIEDIASRIESNnqsiSGGRvselgl 224
Cdd:TIGR00914 691 DDLDDLDATAEK-ISAVLKGVPGAADVKV--EQTTglpYLTVEIDREKAARYGLTVGDVQDTVATA----VGGR------ 757
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 225 qylvKSSSLFSTEADFEnlIVGYKPVQQETSGNSSSE------TVTDLNKAPVFLKEVATVQFVNArPENIVRINGKRSI 298
Cdd:TIGR00914 758 ----MSGETFEGDRRFD--IVIRLPESLRESPQALRQlpiplpLSEDARKQFIPLSDVADLRVSPG-PNQISRENGKRRV 830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 299 GLSIYKEMRfNTVKVVDEVTSRLAVIEDALPGYHfqvISNQGTF--IKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTL 376
Cdd:TIGR00914 831 VVSANVRGR-DLGSFVDDAKKAIAEQVKLPPGYW---ITWGGQFeqLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDAL 906
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 377 IVSLSIPISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIASTL 456
Cdd:TIGR00914 907 LVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTAL 986
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 491930720 457 TTIVVFLPIVYLHGASGELFKDQAWTVTFSLVSSLFVAILVIPMLYTQLSGKKVKMEE 514
Cdd:TIGR00914 987 VASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHRRRHKGRK 1044
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
823-1036 |
1.83e-14 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 77.98 E-value: 1.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 823 MDTGKSLDKVAAEVRLAVKDIDLPaNYSITVTGE----EEKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLT 898
Cdd:COG1033 173 LSSDLDRKEVVAEIRAIIAKYEDP-GVEVYLTGFpvlrGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLV 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 899 IPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILA 978
Cdd:COG1033 252 VLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIG 331
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 491930720 979 MLpmTFGFGEGASLRSpMAIAVIGGLITSTLMSLMVIPCVYYVLEKIKRRINHRTKKS 1036
Cdd:COG1033 332 FL--SLLFSDIPPIRD-FGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPP 386
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
864-1032 |
2.35e-11 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 68.13 E-value: 2.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 864 MHSLLFALLLsVVLVYMVMasqfesLLHP---FTILLTIPLAVVGAILLFFITGTTINMMgvigivMLGGIA------VN 934
Cdd:COG3696 338 TKNLLEGALL-VILVLFLF------LGNLraaLIVALAIPLSLLFAFIVMRLFGISANLM------SLGGLAidfgiiVD 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 935 NSIILVD------RINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLP-MTFGFGEGAsLRSPMAIAVIGGLITS 1007
Cdd:COG3696 405 GAVVMVEnilrrlEENRAAGTPRERLEVVLEAAREVRRPIFFATLIIILVFLPiFTLEGVEGK-LFRPMALTVIFALLGA 483
|
170 180
....*....|....*....|....*
gi 491930720 1008 TLMSLMVIPCVYYVLekIKRRINHR 1032
Cdd:COG3696 484 LLLSLTLVPVLASLL--LRGKVPEK 506
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
353-497 |
3.31e-11 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 66.54 E-value: 3.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 353 SAILGIVLAVIVLFVFLRRMGttLIVSLSIPISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFRNQEK 432
Cdd:TIGR01129 253 AGLIGLVLVLVFMILYYRLFG--LIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRL 330
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491930720 433 GVSVKEAVVTGTAEVANAVIASTLTTIVVFLpIVYLHGASgeLFKDQAWTVTFSLVSSLFVAILV 497
Cdd:TIGR01129 331 GKSVRQAIEAGFERAFSTIFDANITTLIAAL-ILYVFGTG--PVKGFAVTLAIGIIASLFTALVF 392
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
824-1028 |
5.67e-09 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 60.24 E-value: 5.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 824 DTGKSLDKVAAEVRLAVKDIDLPANYSITVTGE-------EEKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTIL 896
Cdd:TIGR00921 148 ADYKQVVPIYNDVERSLERTNPPSGKFLDVTGSpainydiEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVII 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 897 LTIPLAVVGAIllfFITGTTINMMGVIGIVMLGGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTI 976
Cdd:TIGR00921 228 LFGVAWVLGIM---GWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTS 304
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 491930720 977 LAMLPMtfgFGEGASLRSPMAIAVIGGLITSTLMSLMVIPCVYYVLEKIKRR 1028
Cdd:TIGR00921 305 AGFAAL---ALSEFPMVSEFGLGLVAGLITAYLLTLLVLPALLQSIDIGREK 353
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
831-984 |
9.28e-09 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 59.63 E-value: 9.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 831 KVAAEVRLAVKDIDLPANYSITV--TGEEEKRQESM----HSLLFALLLSVVLVYMVMASQFESLLHPFTILLT--IPLA 902
Cdd:TIGR03480 229 KAINAIRAAAKDLRLDEDHGVTVrlTGEVALSDEELatvsEGATVAGLLSFVLVLVLLWLALRSPRLVFAVLVTliVGLI 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 903 VVGAILLFFITgtTINMMGVIGIVMLGGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTT---ILAM 979
Cdd:TIGR03480 309 LTAAFATLAVG--HLNLISVAFAVLFIGLGVDFAIQFSLRYREERFRGGNHREALSVAARRMGAALLLAALATaagFFAF 386
|
....*
gi 491930720 980 LPMTF 984
Cdd:TIGR03480 387 LPTDY 391
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
831-1024 |
4.76e-08 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 54.15 E-value: 4.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 831 KVAAEVRLAVKDIDLPANYSITVTGEEEKRQESMHSLLFALLLsvVLVYMvmASQFEsLLHPFTILLTIPLAVVGAILLF 910
Cdd:pfam02355 1 VVEALLKNVGPDAEIISIETVGPTVGSELARKAVLALLFALLL--ILIYV--GLRFE-WRFALGAIIALAHDVIITVGVF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 911 FITGTTINMMGVIGIVMLGGIAVNNSIILVDRI--NQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFgFGE 988
Cdd:pfam02355 76 SLFGIEVDLATVAALLTIIGYSVNDTVVVFDRVreNLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFV-FGG 154
|
170 180 190
....*....|....*....|....*....|....*..
gi 491930720 989 GaSLRSpMAIAVIGGLITSTLMS-LMVIPCVYYVLEK 1024
Cdd:pfam02355 155 G-SLKD-FSLALLVGVIVGTYSSiFIASPILLDLGER 189
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
784-1035 |
8.79e-08 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 56.39 E-value: 8.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 784 IRSGTQEFLLDEIASITHGQAPKEILRRNQSRIGkimanmDTGKSLDKVAAEVRLAVKDID---LPANYSITVTGEEEKR 860
Cdd:PRK13024 503 VRADLKELGLGEVNIVTFGSDNNQVLVRTYGILS------DDEEADTEIVAKLKNALKNDKggtIPSSETVGPTVGKELA 576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 861 QESMHSLLFALLlsVVLVYMVMasQFE---------SLLHPFTILLTIplavvgaillFFITGTTINMMGVIGIVMLGGI 931
Cdd:PRK13024 577 RNAIIAVLIALI--GILLYILI--RFEwtfslgailALLHDVLIVIGF----------FSLFRLEVDLTFIAAILTIIGY 642
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 932 AVNNSIILVDRINQLSQA--GMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFgFGeGASLRSpMAIAVIGGLITSTL 1009
Cdd:PRK13024 643 SINDTVVVFDRIRENLRLykKKDLREIVNKSINQTLSRTINTSLTTLLVLLALLI-FG-GSSLRN-FSLALLVGLIVGTY 719
|
250 260
....*....|....*....|....*.
gi 491930720 1010 MSLMVIPCVYYVLEKIKRRINHRTKK 1035
Cdd:PRK13024 720 SSIFIAAPLWLDLEKRRLKKKKKRKK 745
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
310-538 |
3.93e-07 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 54.00 E-value: 3.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 310 TVKVVDEVTSRLAviEDALPGYHFQVISNQGT---FIKSAIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISI 386
Cdd:COG2409 130 AAEAVDALRDAVA--AAPAPGLTVYVTGPAALaadLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAGLAV 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 387 VATFNLMFF-------NGLTLNIMTLGGLALGagmlVDNAIVVIeSIFRNQ-EKGVSVKEAVVTGTAEVANAVIASTLTT 458
Cdd:COG2409 208 GVALGLLALlaaftdvSSFAPNLLTMLGLGVG----IDYALFLV-SRYREElRAGEDREEAVARAVATAGRAVLFSGLTV 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 459 IV-----VFLPIVYLHGAsgelfkdqAWTVTFSLVSSLFVAILVIPMLYTqLSGKKV------KMEEVKSIRITRYSKIL 527
Cdd:COG2409 283 AIallglLLAGLPFLRSM--------GPAAAIGVAVAVLAALTLLPALLA-LLGRRVfwprrpRRRRAAAPESGFWRRLA 353
|
250
....*....|.
gi 491930720 528 RKLVRHRWWVI 538
Cdd:COG2409 354 RAVVRRPVPVL 364
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
824-1016 |
1.23e-06 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 52.46 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 824 DTGKSLDKVAAEVRLAVKDIDlPANYSITVTGE----EEKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTI 899
Cdd:COG2409 125 DAGDEAAEAVDALRDAVAAAP-APGLTVYVTGPaalaADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTA 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 900 PLAVVGAILLFF-------ITGTTINMMGVIGIvmlgGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTT 972
Cdd:COG2409 204 GLAVGVALGLLAllaaftdVSSFAPNLLTMLGL----GVGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSG 279
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 491930720 973 LTTILAMLPMTF-GFGegaSLRSpMAIAVIGGLITSTLMSLMVIP 1016
Cdd:COG2409 280 LTVAIALLGLLLaGLP---FLRS-MGPAAAIGVAVAVLAALTLLP 320
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
353-539 |
1.28e-06 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 52.54 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 353 SAILGIVLAVIVLFVFLRRMGttLIVSLSIPISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFRNQEK 432
Cdd:PRK13024 271 AGIIGFALIFLFMLVYYGLPG--LIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRK 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 433 GVSVKEAVVTGTAEVANAVIASTLTTIVVFLpIVYLHGASgeLFKDQAWTVTFSLVSSLFVAILVIPMLYTQLSGKKVKM 512
Cdd:PRK13024 349 GKSLKKAFKKGFKNAFSTILDSNITTLIAAA-ILFFFGTG--PVKGFATTLIIGILASLFTAVFLTRLLLELLVKRGDKK 425
|
170 180 190
....*....|....*....|....*....|....*
gi 491930720 513 EE---VKSIRITRYSKILRK-----LVRHRWWVIG 539
Cdd:PRK13024 426 PFlfgVKKKKIHNINEGVTIfdridFVKKRKWFLI 460
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
343-504 |
1.35e-06 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 52.31 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 343 IKSAIGE-VKSSAILGIVLAVIV--LFVFLRRMGTTLIVSLSIPISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNA 419
Cdd:PRK13023 268 IASALGEdYASAAVLAALLAALVvgLFMVLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAH 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 420 IVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGASGELFkdqAWTVTFSLVSSLFVAILVIP 499
Cdd:PRK13023 348 ILIYERVREDRRKGYSVVQAMESGFYRALSTIVDANLTTLIAALVLFLLGSGTVHGF---ALTVAIGIGTTLFTTLTFTR 424
|
....*
gi 491930720 500 MLYTQ 504
Cdd:PRK13023 425 LLIAQ 429
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
822-1016 |
1.35e-06 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 51.52 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 822 NMDTGKSLDKVAAeVRLAVKDIDLPANYSITVTGE----EEKRQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILL 897
Cdd:pfam03176 96 DPGTTEADESVAA-VRDAVEQAPPPEGLKAYLTGPaatvADLRDAGDRDLGLIEAVTLVVIFIILLIVYRSVVAALLPLL 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 898 TIPL---------AVVGAILLFFITGTTINMMGVIGIvmlgGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPI 968
Cdd:pfam03176 175 TVGLslgaaqglvAILAHILGIGLSTFALNLLVVLLI----AVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVV 250
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 491930720 969 IMTTLTTILAMLPMTFgfgegASLRS--PMAIAVIGGLITSTLMSLMVIP 1016
Cdd:pfam03176 251 TAAGLTVAIAMLALSF-----ARLPVfaQVGPTIAIGVLVDVLAALTLLP 295
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
861-1036 |
1.46e-06 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 52.42 E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 861 QESMHSLLFALLLSVVLVYMVM---ASQFESLLHPftiLLTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSI 937
Cdd:TIGR00915 334 EASIEEVVHTLIEAIVLVFLVMylfLQNFRATLIP---TIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLVDDAI 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 938 ILVDRINQL-SQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRSPMAIAVIGGLITSTLMSLMVIP 1016
Cdd:TIGR00915 411 VVVENVERVmAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTP 490
|
170 180
....*....|....*....|
gi 491930720 1017 CVYYVLEKIKRRINHRTKKS 1036
Cdd:TIGR00915 491 ALCATMLKPIEKGEHHEKKG 510
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
349-502 |
1.47e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 52.15 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 349 EVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESiFR 428
Cdd:TIGR00921 568 GMRRMTIAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHLAER-YF 646
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491930720 429 NQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGAsgeLFKDQAWTVTFSLVSSLFVAILVIPMLY 502
Cdd:TIGR00921 647 EERKEHGPKEAITHTMERTGPGILFSGLTTAGGFLSLLLSHFP---IMRNFGLVQGIGVLSSLTAALVVFPALL 717
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
354-463 |
2.21e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 51.76 E-value: 2.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 354 AILGIVLAVIVLFVF--LRRMGTTLIVSLSipiSIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESIFRNQE 431
Cdd:TIGR00921 200 AISGILVVLVLLLDFkrWWRPLLPLVIILF---GVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERD 276
|
90 100 110
....*....|....*....|....*....|..
gi 491930720 432 KGVSVKEAVVTGTAEVANAVIASTLTTIVVFL 463
Cdd:TIGR00921 277 IGRAKGEAIVTAVRRTGRAVLIALLTTSAGFA 308
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
788-1014 |
2.50e-06 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 49.96 E-value: 2.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 788 TQEFLLDEIASITHGQAPKEILRRNQSRIGKIMANMDTgkSLDKVAAEVRLAVKDIDLPANYSITVTGEE--------EK 859
Cdd:TIGR00966 19 EQAADVAEVRDVLEKAGIEGVVIQEFGSSHTIMIRIPT--LDTEQSEELREALEEALKNVDPDAEIRSIDavgpsvggEL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 860 RQESMHSLLFALLLsvVLVYMvmASQFE---------SLLHPFTILLTIplavvgaillFFITGTTINMMGVIGIVMLGG 930
Cdd:TIGR00966 97 ARKAVLALLAALVL--ILIYI--TVRFEwrfalgaivALVHDVIITVGV----------YSLFGIEVNLTTVAALLTIIG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 931 IAVNNSIILVDRI--NQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFgFGEGaSLRSpMAIAVIGGLITST 1008
Cdd:TIGR00966 163 YSINDTVVVFDRIreNLRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYV-FGGG-VIKD-FSLALLVGVIVGT 239
|
....*.
gi 491930720 1009 LMSLMV 1014
Cdd:TIGR00966 240 YSSIFI 245
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
863-1036 |
2.74e-06 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 51.44 E-value: 2.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 863 SMHSLLFALLLSVVLVYMVM---ASQFESLLHPfTIllTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSIIL 939
Cdd:PRK15127 336 SIHEVVKTLVEAIILVFLVMylfLQNFRATLIP-TI--AVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVV 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 940 VDRINQ-LSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRSPMAIAVIGGLITSTLMSLMVIPCV 1018
Cdd:PRK15127 413 VENVERvMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPAL 492
|
170
....*....|....*...
gi 491930720 1019 YYVLEKIKRRINHRTKKS 1036
Cdd:PRK15127 493 CATMLKPIAKGDHGEGKK 510
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
353-515 |
1.14e-05 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 49.07 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 353 SAILGIVLAVIVLFVFLRRMGttLIVSLSIPISIVATFNLMFFNGLTLnimTL---GGLALGAGMLVDNAIVVIESI--- 426
Cdd:PRK05812 302 AGLIGLALVLLFMILYYRLFG--LIANIALVANLVLILAVLSLLGATL---TLpgiAGIVLTIGMAVDANVLIFERIree 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 427 FRNqekGVSVKEAVVTGTAEVANAVIASTLTTIVVFLpIVYLHGaSGELfKDQAWTVTFSLVSSLFVAILVIPMLYTQLS 506
Cdd:PRK05812 377 LRE---GRSLRSAIEAGFKRAFSTILDSNITTLIAAI-ILYALG-TGPV-KGFAVTLGIGILTSMFTAITVTRALVNLLY 450
|
....*....
gi 491930720 507 GKKVKMEEV 515
Cdd:PRK05812 451 GRRKRLKKL 459
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
250-518 |
1.93e-05 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 48.96 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 250 VQQETSGNSSSETVTDL---NKAPVF--LKEVATVQFVNARPEnIVRINGKRSIGLSIYKEMRFNTVKVVDEVtsrlAVI 324
Cdd:TIGR00915 772 VQAEEDARMSPEDINKWyvrNASGEMvpFSAFATVRWEYGSPQ-LERYNGLPSMEILGSAAPGVSTGQAMAAM----EAI 846
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 325 EDALP---GYHFQVISNQgtfiksaigEVKSSAILGIVLAVIVLFVFL------RRMGTTLIVSLSIPISIVATFNLMFF 395
Cdd:TIGR00915 847 AQKLPpgfGFSWTGMSYE---------ERLSGSQAPALYALSLLVVFLclaalyESWSIPVSVMLVVPLGIIGALLATTL 917
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 396 NGLTLNIMTLGGLALGAGMLVDNAIVVIESIFRNQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLHGASGEL 475
Cdd:TIGR00915 918 RGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGS 997
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 491930720 476 FKDQAWTVTFSLVSSLFVAILVIPMLY----TQLSGKKVKMEEVKSI 518
Cdd:TIGR00915 998 QHAIGTGVFGGMVTATVLAIFFVPLFYvvvrRLFKRKAHEKEMSVEH 1044
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
354-501 |
3.41e-05 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 48.07 E-value: 3.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 354 AILGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDNAIVVIESiFRNqekG 433
Cdd:TIGR03480 718 FIYALVAITVLLLLTLRRVRDVLLVLAPLLLAGLLTVAAMVLLGIPFNFANIIALPLLLGLGVDFGIYMVHR-WRN---G 793
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491930720 434 VSVKEAVVTGTAEvanAVIASTLTTIVVFLPIVYLHG---AS-GELfkdqawtVTFSLVSSLFVAILVIPML 501
Cdd:TIGR03480 794 VDSGNLLQSSTAR---AVFFSALTTATAFGSLAVSSHpgtASmGIL-------LSLGLGLTLLCTLIFLPAL 855
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
861-1035 |
6.69e-05 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 47.13 E-value: 6.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 861 QESMHSLLFALLLSVVLVYMVM---ASQFESLLHPfTIllTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSI 937
Cdd:PRK10555 334 KASIEDVVKTLLEAIALVFLVMylfLQNFRATLIP-TI--AVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLVDDAI 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 938 ILVDRINQL-SQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFGFGEGASLRSPMAIAVIGGLITSTLMSLMVIP 1016
Cdd:PRK10555 411 VVVENVERImSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAMILTP 490
|
170
....*....|....*....
gi 491930720 1017 CVYYVLEKIKRRINHRTKK 1035
Cdd:PRK10555 491 ALCATLLKPLKKGEHHGQK 509
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
845-1009 |
7.44e-05 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 47.02 E-value: 7.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 845 LPAnysiTVTGEEEKR------QESMHSLLFALLLSVVLV--YMVMASQFESLLHpfTILLTIPLAVVGAILLffITGTT 916
Cdd:PRK14726 350 LPA----TLTVVEERTvgpglgADSIAAGLVAGLIAAILVaaLMIGFYGFLGVIA--VIALIVNVVLIIAVLS--LLGAT 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 917 INMMGVIGIVMLGGIAVNNSIILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLpMTFGFGEGASlrSPM 996
Cdd:PRK14726 422 LTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLIQALDRGFSRALATIVDANVTILIAAV-ILFFLGSGAV--RGF 498
|
170
....*....|...
gi 491930720 997 AIAVIGGLITSTL 1009
Cdd:PRK14726 499 AVTLAVGILTTVF 511
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
356-462 |
1.42e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 46.00 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 356 LGIVLAVIVLFVFLRRMGTTLIVSLSIPISIVATFNLMFFNGLTLNIMTLGGLALGAGMLVDnaivviESIFrNQEKGVS 435
Cdd:COG4258 647 LALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGID------YALF-FTEGLLD 719
|
90 100
....*....|....*....|....*..
gi 491930720 436 VKEAVVTGTaevanAVIASTLTTIVVF 462
Cdd:COG4258 720 KGELARTLL-----SILLAALTTLLGF 741
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
346-494 |
2.23e-04 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 45.48 E-value: 2.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 346 AIGEVKSSAILGIVLAVIVLFVFLRRMGTTLIVSLSIPIS-IVATFNLMffnGLTLNIMTLGGLALGAGMLVDNAIVVIE 424
Cdd:PRK14726 370 SIAAGLVAGLIAAILVAALMIGFYGFLGVIAVIALIVNVVlIIAVLSLL---GATLTLPGIAGIVLTIGMAVDSNVLIYE 446
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 425 SIFRNQEKGVSVKEAVVTGTAEVANAVIASTLTTIVVFLPIVYLhgaSGELFKDQAWTVTFSLVSSLFVA 494
Cdd:PRK14726 447 RIREEEKTGHSLIQALDRGFSRALATIVDANVTILIAAVILFFL---GSGAVRGFAVTLAVGILTTVFTA 513
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
868-1014 |
6.24e-04 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 43.12 E-value: 6.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 868 LFALLLSVVLVYMVMASQFE---------SLLHpfTILLTIplavvGailLFFITGTTINMMGVIGIVMLGGIAVNNSII 938
Cdd:COG0341 136 LLALLVALIGILIYIAFRFEwrfavgavvALLH--DVLITL-----G---IFSLFGLEFDLTFIAALLTIIGYSLNDTVV 205
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491930720 939 LVDRI--NQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFgFGeGASLRSpMAIAVIGGLITSTLMSLMV 1014
Cdd:COG0341 206 VFDRIreNLRKYRKMTLAEIINLSINQTLSRTINTSLTTLLVVLALLF-FG-GETLRD-FALALLIGIIVGTYSSIFI 280
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
860-1018 |
1.13e-03 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 42.83 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 860 RQESMHSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPL-------AVV-----GAILLFFITGTTINMMGVIGIVM 927
Cdd:COG2409 512 SDALADDLPLVIPVVLGLIFLLLLLLFRSVVAPLKAVLTNLLslgaalgVLVlvfqhGWLLLGFTPGPLDSFVPLLLFVI 591
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 928 LGGIAVNNSIILVDRINQLSQAGMELTDAIVE-----------AGqqrirpIIMTTLTTILAMLPMTF----GFGegasl 992
Cdd:COG2409 592 LFGLGMDYEVFLVSRIREEYDRGGGTREAVIRglartgrvitsAA------LIMAAVFAAFATSPLVFlkqiGFG----- 660
|
170 180
....*....|....*....|....*.
gi 491930720 993 rspMAIAViggLITSTLMSLMVIPCV 1018
Cdd:COG2409 661 ---LAVGV---LLDAFVVRMLLVPAL 680
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
861-1014 |
2.41e-03 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 41.50 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 861 QESMHSLLFALL--LSVVLVYMVMASQFESLLHPFTILLTIPLAVvgAILLFFitGTTINMMGVIGIVMLGGIAVNNSII 938
Cdd:TIGR01129 244 ADSIEAGIKAGLigLVLVLVFMILYYRLFGLIAAIALVINIVLIL--AILSAF--GATLTLPGIAGLILTIGMAVDANVL 319
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491930720 939 LVDRINQLSQAGMELTDAIvEAGQQRIRPIIM-TTLTTILAMLPMTFgFGEGASlrSPMAIAVIGGLITSTLMSLMV 1014
Cdd:TIGR01129 320 IYERIKEELRLGKSVRQAI-EAGFERAFSTIFdANITTLIAALILYV-FGTGPV--KGFAVTLAIGIIASLFTALVF 392
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
865-1016 |
2.66e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 41.76 E-value: 2.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 865 HSLLFALLLSVVLVYMVMASQFESLLHPFTILLTIPLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSIILVDRIN 944
Cdd:COG4258 639 NDALWLLLLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTEGLL 718
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491930720 945 QlsqagmeltdaivEAGQQRIRP-IIMTTLTTILamlpmTFG---FGEGASLRSpMAIAVIGGLITSTLMSLMVIP 1016
Cdd:COG4258 719 D-------------KGELARTLLsILLAALTTLL-----GFGllaFSSTPALRS-FGLTVLLGILLALLLAPLLAP 775
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
860-1016 |
4.71e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 41.00 E-value: 4.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 860 RQESMHSLLFALllSVVLVYMVMasQFE---------SLLHpfTILLTIPLAVvgaILLFFITGTTINMMGVIGIVMLGG 930
Cdd:PRK12911 1233 RTQAVIALFGAL--GIILLYVSL--RFEwryafsaicALIH--DLLATCAVLV---ALHFFLQKIQIDLQAIGALMTVLG 1303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 931 IAVNNSIILVDRINQLSQAGM--ELTDAIVEAGQQRIRPIIMTTLTTILAMLPMTFgFGeGASLRSPMAIAVIGGLItST 1008
Cdd:PRK12911 1304 YSLNNTLIIFDRIREDRQEKLftPMPILINDALQKTLGRTVMTTATTLSVLLILLF-VG-GGSIFNFAFIMTIGILL-GT 1380
|
....*...
gi 491930720 1009 LMSLMVIP 1016
Cdd:PRK12911 1381 LSSLYIAP 1388
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
861-1014 |
8.08e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 40.22 E-value: 8.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 861 QESMHSLLFALLLSVVLV--YMVMASQFesllhpFTILLTIPLAVVGAILLFFIT--GTTINMMGVIGIVMLGGIAVNNS 936
Cdd:PRK13024 262 QDAIDAGIIAGIIGFALIflFMLVYYGL------PGLIANIALLLYIFLTLGALSslGAVLTLPGIAGLVLGIGMAVDAN 335
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491930720 937 IILVDRINQLSQAGMELTDAIVEAGQQRIRPIIMTTLTTILAMLpMTFGFGEGaSLRSpMAIAVIGGLITSTLMSLMV 1014
Cdd:PRK13024 336 VLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITTLIAAA-ILFFFGTG-PVKG-FATTLIIGILASLFTAVFL 410
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
821-1014 |
8.16e-03 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 39.45 E-value: 8.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 821 ANMDTGKSLDKVAAEVRLAVKDID-LPANYSITVTGEEEKRQESMhsllfALLLSVVLVYMVMASQFESLLHPFTiLLTI 899
Cdd:PRK13021 86 APADTAQSNVDIQQALAPLGTEVQvLNSSIVGPQVGQELAEQGGL-----ALLVAMLCILGYLSYRFEWRLASGA-LFAL 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491930720 900 PLAVVGAILLFFITGTTINMMGVIGIVMLGGIAVNNSIILVDRINQLSQAGMELtdAIVEAGQQRI-----RPIIM--TT 972
Cdd:PRK13021 160 VHDVIFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKL--AIQEINNQAIvatfsRTMVTsgTT 237
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 491930720 973 LTTILAMLPMTFGFGEGaslrspMAIAVIGGLITSTLMSLMV 1014
Cdd:PRK13021 238 LMTVGALWIMGGGPLEG------FSIAMFIGILTGTFSSISV 273
|
|
|