|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP2A |
NF038276 |
streptococcal penicillin-binding protein PBP2A; |
11-680 |
0e+00 |
|
streptococcal penicillin-binding protein PBP2A;
Pssm-ID: 439576 [Multi-domain] Cd Length: 716 Bit Score: 737.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 11 IRWFFRRFQVIRWLILLGLTVILIFSAWFTYKAKTADVQNIKSTLQTKTVIYDANNEEAGTLYGQKGTYVELSAISPQVQ 90
Cdd:NF038276 30 IRRFWRRYHLGKILLILGGTFVLLVGSYLFYLAKTTNVSDLQNALKATTVIYDKDGKEAGSLSGQKGTYVELDAISDDLE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 91 NAVISTEDRTFYSNGGFSIKgilRSALNyVIHHGQiMGGGSTITQQLAKNTLLTQKQTMLRKAQELFMAIQLNKVYSKQD 170
Cdd:NF038276 110 NAVIATEDRSFYKNSGINYK---RFFLA-ILTAGR-FGGGSTITQQLAKNAYLSQDQTIKRKAKEFFLALELTKKYSKKE 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 171 ILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVLQLMVDNHKLTQA 250
Cdd:NF038276 185 ILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTLDEAATLAGMLKGPEIYNPLYSIENATNRRDTVLQNMVDAGKIDQA 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 251 QANAAKAQSV--QVVDAFS-NANAQKYPSYFDSVIEEARSE-GISVDDILNKGYKIYTNLDQTYQQNLQTSFEQDWAFPA 326
Cdd:NF038276 265 QADEAAAVDMgsRLADTYEgKSDDYRYPSYFDAVINEAISKyGLSEKDIVNNGYKIYTELDQNYQAGMQVTFDNTSLFPV 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 327 NAADGKQVQGASIILDPKTGGVRAVVG---NRGEHTFLGFNYATQLRNSPGSTIKPLMVYTPALENGYHYDSILKDEKLS 403
Cdd:NF038276 345 SEYDGTSAQSASVALDPKTGGVRGLVGrvnSTENATFRSFNYATQSKRSPGSTIKPLVVYSPAVASGWSIDKELPNTTQD 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 404 YGknNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQLKSSDQNLAAALGGlknGV--SPLM 481
Cdd:NF038276 425 YD--GYKPHNYGGIESEDVPMYQALANSYNIPAVYTLNELGIDKAFSYGKKFGLNMDKVDKELGVALGG---GVttNPLE 499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 482 LARAYAAFANDGKLPTTHFIRKIVDASGETVVDNSHPATRqIMSKKVAQEMTSMMIGTFNEGTGKTAKPSGYTIAGKTGS 561
Cdd:NF038276 500 MAQAYATFANGGVMPDAHLITRIENASGKVIKTHKDKSKR-VISQSVADKMTSMMLGTFSNGTGVNANVYGYTMAGKTGT 578
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 562 TEVPSSWGYgTKDQWVVGYTPDIVNATWIGYPTTDSQHFLQGTSTSGVAPLFKLEMSKLMPNTPQTAFDTKDA------- 634
Cdd:NF038276 579 TETDFNPDL-SSDQWVIGYTPDVVISQWLGFPKTDENHYLTDSSSGTASTIFSTVASYILPYTKGTEFTVENAyaqngia 657
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 491946630 635 ----AQMASIQTPGKSDDTWQGIQ-------DSIDKGIDSA--KETVGKWYDNIKSWFK 680
Cdd:NF038276 658 pvytANETSTETSSESQDIIDDIResaqnavDSASKAVDDAgiKEKAKSLWDSIVDWFR 716
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-649 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 663.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 1 MQVLSRVWQSIRWFFRRFqvirwLILLGLTVILIFSAWFTYKAKTA-DVQNIKS-TLQTKTVIYDANNEEAGTLYGQKGT 78
Cdd:COG0744 1 MAKPRRGKRLLRRLLGLL-----LLLLAVLVLAALAGLVALYVADLpDPEELEDlALPQTSTIYDRDGTLIATLGDENRE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 79 YVELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSALNYvIHHGQIMGGGSTITQQLAKNTLLTQKQTMLRKAQELFM 158
Cdd:COG0744 76 WVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVAN-LTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 159 AIQLNKVYSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVL 238
Cdd:COG0744 155 ALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 239 QLMVDNHKLTQAQANAAKAQSVQVVDAFSNANAQKYPSYFDSVIEEARSEgISVDDILNKGYKIYTNLDQTYQQNLQTSF 318
Cdd:COG0744 235 DRMVEQGYITQAEADAAKAEPLTLVPPPNGAAAGKYPYFVDYVRRELEEL-LGEDDLYRGGLKIYTTLDPKLQKAAEKAV 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 319 EQdwAFPANaaDGKQVQGASIILDPKTGGVRAVVGNRgEHTFLGFNYATQLRNSPGSTIKPLmVYTPALENGYHYDSILK 398
Cdd:COG0744 314 KN--VLPEG--KPGGLQAALVVVDPKTGEVLAMVGGR-DYGKSQFNRATQAKRQPGSTFKPF-VYAAALEQGYTPATTVD 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 399 DEKLSYGKNNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQlKSSDQNLAAALGGlkNGVS 478
Cdd:COG0744 388 DEPVTFPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPNPSLALGT--SEVS 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 479 PLMLARAYAAFANDGKLPTTHFIRKIVDASGETVVDNShPATRQIMSKKVAQEMTSMMIGTFNEGTGKTAKPSGYTIAGK 558
Cdd:COG0744 465 PLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAK-PKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGK 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 559 TGSTEvpsswgyGTKDQWVVGYTPDIVNATWIGYPTTDSQHFLQGtsTSGVAPLFKLEMSKLMPNTPQTAFDTKDAAQMA 638
Cdd:COG0744 544 TGTTN-------DNRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTG--GSLPAPIWRDFMEAALEGLPVEDFPKPSGVVRI 614
|
650
....*....|.
gi 491946630 639 SIQTPGKSDDT 649
Cdd:COG0744 615 DEPSPTPSGTE 625
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
76-623 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 586.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 76 KGTYVELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSALNyVIHHGQIMGGGSTITQQLAKNTLLTQKQTMLRKAQE 155
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVA-NITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 156 LFMAIQLNKVYSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRN 235
Cdd:TIGR02074 80 ALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 236 VVLQLMVDNHKLTQAQANAAKAQSVQVVDAFSNANAQKYPSYFDSVIEEARSE-GisvDDILNKGYKIYTNLDQTYQQNL 314
Cdd:TIGR02074 160 LVLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQYKAPYFVDYVIQELEEEyG---EELYTGGLKIYTTLDLDAQKAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 315 QTSFEQDWAFPaNAADGKQVQGASIILDPKTGGVRAVVGNRGeHTFLGFNYATQLRNSPGSTIKPLmVYTPALENGYHYD 394
Cdd:TIGR02074 237 EKVLNTGLRVA-GRRDGDDLQAALVAIDPDTGAVRALVGGRD-YGKSQFNRATQAKRQPGSTFKPF-VYAAALEKGLTPA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 395 SILKDEKLSYGKN-NYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQLKSSDqNLAAALGGl 473
Cdd:TIGR02074 314 TIVNDEPITYNGNgPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLDP-VLSLALGT- 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 474 kNGVSPLMLARAYAAFANDGKLPTTHFIRKIVDASGETVVDNShPATRQIMSKKVAQEMTSMMIGTFNEGTGKTAKPSGY 553
Cdd:TIGR02074 392 -VEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENK-PKTTQVISPATAYIMTDMLKGVVESGTGRSARLPGR 469
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 554 TIAGKTGSTEVpsswgygTKDQWVVGYTPDIVNATWIGYPTTDSqHFLQGTSTSGVAPLFKLEMSKLMPN 623
Cdd:TIGR02074 470 PVAGKTGTTQN-------WRDAWFVGYTPYYVTAVWVGYDDKKT-LGKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
65-242 |
4.21e-83 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 259.76 E-value: 4.21e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 65 NNEEAGTLYGQKGTYVELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSALNyVIHHGQIMGGGSTITQQLAKNTLLT 144
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLS-NLRSGRIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 145 QKQTMLRKAQELFMAIQLNKVYSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPA 224
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 491946630 225 DHKDNAISRRNVVLQLMV 242
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
21-611 |
1.99e-63 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 225.78 E-value: 1.99e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 21 IRWLILLGLTVIL-----IFSAWFTYKAKTADVQNIKST-LQTKTVIYDANNEEAGTlYGQKGTY-VELSAISPQVQNAV 93
Cdd:PRK11636 4 VKYLLILAVCCILlgagsIYGLYRYIEPQLPDVATLKDVrLQTPMQVYSADGELIAQ-YGEKRRIpLTLDQIPPEMVKAF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 94 ISTEDRTFYSNGGFSIKGILRSAlNYVIHHGQIMGGGSTITQQLAKNTLLTQKQTMLRKAQELFMAIQLNKVYSKQDILA 173
Cdd:PRK11636 83 IATEDSRFYEHHGVDPVGIFRAA-SVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 174 MYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVLQLMVDNHKLTQAqan 253
Cdd:PRK11636 162 LYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQA--- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 254 aakaqsvQVVDAFSNANAQKY--PSYFDS---VIEEARSEGISV--DDILNKGYKIYTNLDQTYQQNLQTSF-------- 318
Cdd:PRK11636 239 -------QYDQARSEPIVANYhaPEIAFSapyLSEMVRQEMYNRygENAYEDGYRVYTTITRKVQQAAQQAVrnnvldyd 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 319 ----------------EQDWA-----------------FPA-----NA-------ADGKQV------------------Q 335
Cdd:PRK11636 312 mrhgyrgpanvlwkvgESAWDnkkitdtlkalptygplLPAvvtsaNPqeatamlADGSSValpmegvrwarpyrsdtqQ 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 336 GAS-----------------------------------IILDPKTGGVRAVVG----NRGEhtflgFNYATQLRNSPGST 376
Cdd:PRK11636 392 GPTprkvtdvvqtgqqiwvrqvddawwlaqvpdvnsalVSINPQNGAVMALVGgfdfNQSK-----FNRATQALRQVGSN 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 377 IKPLMvYTPALENGYHYDSILKDEKLSY----GKNNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASL 452
Cdd:PRK11636 467 IKPFL-YTAAMDKGLTLASMLNDVPISRwdagAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYL 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 453 DRFGIQLKSSDQNLAAALGGlkNGVSPLMLARAYAAFANDGKLPTTHFIRKIVDASGETV-------------------- 512
Cdd:PRK11636 546 QRFGFPAQNIVHTESLALGS--ASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIfeakpkvacpecdipviygd 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 513 --------------VDNSH-------------PATRQIMSKKVAQEMTSMMIGT--------------FNE----GTGKT 547
Cdd:PRK11636 624 tqksnvlenddvenVATSQeqqnssvpmpqleQANQALVAQNGAQEYAPHVINTplafliksalntniFGEpgwmGTGWR 703
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491946630 548 AKP--SGYTIAGKTGSTEvpSSwgygtKDQWVVGYTPDIVNATWIGYptTDSQHFLQGTSTSGVAP 611
Cdd:PRK11636 704 AGRdlKRRDIGGKTGTTN--SS-----KDAWFSGYGPGVVTSVWIGF--DDHRRDLGRTTASGAIK 760
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP2A |
NF038276 |
streptococcal penicillin-binding protein PBP2A; |
11-680 |
0e+00 |
|
streptococcal penicillin-binding protein PBP2A;
Pssm-ID: 439576 [Multi-domain] Cd Length: 716 Bit Score: 737.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 11 IRWFFRRFQVIRWLILLGLTVILIFSAWFTYKAKTADVQNIKSTLQTKTVIYDANNEEAGTLYGQKGTYVELSAISPQVQ 90
Cdd:NF038276 30 IRRFWRRYHLGKILLILGGTFVLLVGSYLFYLAKTTNVSDLQNALKATTVIYDKDGKEAGSLSGQKGTYVELDAISDDLE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 91 NAVISTEDRTFYSNGGFSIKgilRSALNyVIHHGQiMGGGSTITQQLAKNTLLTQKQTMLRKAQELFMAIQLNKVYSKQD 170
Cdd:NF038276 110 NAVIATEDRSFYKNSGINYK---RFFLA-ILTAGR-FGGGSTITQQLAKNAYLSQDQTIKRKAKEFFLALELTKKYSKKE 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 171 ILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVLQLMVDNHKLTQA 250
Cdd:NF038276 185 ILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTLDEAATLAGMLKGPEIYNPLYSIENATNRRDTVLQNMVDAGKIDQA 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 251 QANAAKAQSV--QVVDAFS-NANAQKYPSYFDSVIEEARSE-GISVDDILNKGYKIYTNLDQTYQQNLQTSFEQDWAFPA 326
Cdd:NF038276 265 QADEAAAVDMgsRLADTYEgKSDDYRYPSYFDAVINEAISKyGLSEKDIVNNGYKIYTELDQNYQAGMQVTFDNTSLFPV 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 327 NAADGKQVQGASIILDPKTGGVRAVVG---NRGEHTFLGFNYATQLRNSPGSTIKPLMVYTPALENGYHYDSILKDEKLS 403
Cdd:NF038276 345 SEYDGTSAQSASVALDPKTGGVRGLVGrvnSTENATFRSFNYATQSKRSPGSTIKPLVVYSPAVASGWSIDKELPNTTQD 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 404 YGknNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQLKSSDQNLAAALGGlknGV--SPLM 481
Cdd:NF038276 425 YD--GYKPHNYGGIESEDVPMYQALANSYNIPAVYTLNELGIDKAFSYGKKFGLNMDKVDKELGVALGG---GVttNPLE 499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 482 LARAYAAFANDGKLPTTHFIRKIVDASGETVVDNSHPATRqIMSKKVAQEMTSMMIGTFNEGTGKTAKPSGYTIAGKTGS 561
Cdd:NF038276 500 MAQAYATFANGGVMPDAHLITRIENASGKVIKTHKDKSKR-VISQSVADKMTSMMLGTFSNGTGVNANVYGYTMAGKTGT 578
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 562 TEVPSSWGYgTKDQWVVGYTPDIVNATWIGYPTTDSQHFLQGTSTSGVAPLFKLEMSKLMPNTPQTAFDTKDA------- 634
Cdd:NF038276 579 TETDFNPDL-SSDQWVIGYTPDVVISQWLGFPKTDENHYLTDSSSGTASTIFSTVASYILPYTKGTEFTVENAyaqngia 657
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 491946630 635 ----AQMASIQTPGKSDDTWQGIQ-------DSIDKGIDSA--KETVGKWYDNIKSWFK 680
Cdd:NF038276 658 pvytANETSTETSSESQDIIDDIResaqnavDSASKAVDDAgiKEKAKSLWDSIVDWFR 716
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-649 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 663.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 1 MQVLSRVWQSIRWFFRRFqvirwLILLGLTVILIFSAWFTYKAKTA-DVQNIKS-TLQTKTVIYDANNEEAGTLYGQKGT 78
Cdd:COG0744 1 MAKPRRGKRLLRRLLGLL-----LLLLAVLVLAALAGLVALYVADLpDPEELEDlALPQTSTIYDRDGTLIATLGDENRE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 79 YVELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSALNYvIHHGQIMGGGSTITQQLAKNTLLTQKQTMLRKAQELFM 158
Cdd:COG0744 76 WVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVAN-LTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 159 AIQLNKVYSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVL 238
Cdd:COG0744 155 ALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 239 QLMVDNHKLTQAQANAAKAQSVQVVDAFSNANAQKYPSYFDSVIEEARSEgISVDDILNKGYKIYTNLDQTYQQNLQTSF 318
Cdd:COG0744 235 DRMVEQGYITQAEADAAKAEPLTLVPPPNGAAAGKYPYFVDYVRRELEEL-LGEDDLYRGGLKIYTTLDPKLQKAAEKAV 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 319 EQdwAFPANaaDGKQVQGASIILDPKTGGVRAVVGNRgEHTFLGFNYATQLRNSPGSTIKPLmVYTPALENGYHYDSILK 398
Cdd:COG0744 314 KN--VLPEG--KPGGLQAALVVVDPKTGEVLAMVGGR-DYGKSQFNRATQAKRQPGSTFKPF-VYAAALEQGYTPATTVD 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 399 DEKLSYGKNNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQlKSSDQNLAAALGGlkNGVS 478
Cdd:COG0744 388 DEPVTFPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPNPSLALGT--SEVS 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 479 PLMLARAYAAFANDGKLPTTHFIRKIVDASGETVVDNShPATRQIMSKKVAQEMTSMMIGTFNEGTGKTAKPSGYTIAGK 558
Cdd:COG0744 465 PLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAK-PKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGK 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 559 TGSTEvpsswgyGTKDQWVVGYTPDIVNATWIGYPTTDSQHFLQGtsTSGVAPLFKLEMSKLMPNTPQTAFDTKDAAQMA 638
Cdd:COG0744 544 TGTTN-------DNRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTG--GSLPAPIWRDFMEAALEGLPVEDFPKPSGVVRI 614
|
650
....*....|.
gi 491946630 639 SIQTPGKSDDT 649
Cdd:COG0744 615 DEPSPTPSGTE 625
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
76-623 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 586.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 76 KGTYVELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSALNyVIHHGQIMGGGSTITQQLAKNTLLTQKQTMLRKAQE 155
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVA-NITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 156 LFMAIQLNKVYSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRN 235
Cdd:TIGR02074 80 ALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 236 VVLQLMVDNHKLTQAQANAAKAQSVQVVDAFSNANAQKYPSYFDSVIEEARSE-GisvDDILNKGYKIYTNLDQTYQQNL 314
Cdd:TIGR02074 160 LVLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQYKAPYFVDYVIQELEEEyG---EELYTGGLKIYTTLDLDAQKAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 315 QTSFEQDWAFPaNAADGKQVQGASIILDPKTGGVRAVVGNRGeHTFLGFNYATQLRNSPGSTIKPLmVYTPALENGYHYD 394
Cdd:TIGR02074 237 EKVLNTGLRVA-GRRDGDDLQAALVAIDPDTGAVRALVGGRD-YGKSQFNRATQAKRQPGSTFKPF-VYAAALEKGLTPA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 395 SILKDEKLSYGKN-NYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQLKSSDqNLAAALGGl 473
Cdd:TIGR02074 314 TIVNDEPITYNGNgPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLDP-VLSLALGT- 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 474 kNGVSPLMLARAYAAFANDGKLPTTHFIRKIVDASGETVVDNShPATRQIMSKKVAQEMTSMMIGTFNEGTGKTAKPSGY 553
Cdd:TIGR02074 392 -VEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENK-PKTTQVISPATAYIMTDMLKGVVESGTGRSARLPGR 469
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 554 TIAGKTGSTEVpsswgygTKDQWVVGYTPDIVNATWIGYPTTDSqHFLQGTSTSGVAPLFKLEMSKLMPN 623
Cdd:TIGR02074 470 PVAGKTGTTQN-------WRDAWFVGYTPYYVTAVWVGYDDKKT-LGKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
12-629 |
1.66e-150 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 455.39 E-value: 1.66e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 12 RWFFRRFQVIrwLILLGLTVILIFSAWFTYKAKTADVQNIKS-TLQTKTVIYDANNEEAGTLYGQKGTYVELSAISPQVQ 90
Cdd:COG5009 2 RLLKILLILL--LLLLLLGALAVAGLYLYLSPDLPDVETLKDyQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 91 NAVISTEDRTFYSNGGFSIKGILRSALNYVIHhGQIMGGGSTITQQLAKNTLLTQKQTMLRKAQELFMAIQLNKVYSKQD 170
Cdd:COG5009 80 NAFLAAEDKRFYEHPGVDPIGIARAAVVNLRT-GRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 171 ILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVLQLMVDNHKLTQA 250
Cdd:COG5009 159 ILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 251 QANAAKAQSVQVVdaFSNANAQKYPSYFdsvIEEARSEGIS---VDDILNKGYKIYTNLDQTYQQNLQTSFEQ------- 320
Cdd:COG5009 239 EYEAAKAEPLTAR--YHGASAEVDAPYF---AEMVRRELVErygEDALYTGGLKVYTTLDPRLQEAAEKALRDgllaydr 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 321 -------------------------------------------------------------DWAFPANAADGK------- 332
Cdd:COG5009 314 rhgyrgpeahldlaeedwdealaevpdvgdlrpavvlevddksarvglrdgetgtlpleglKWARPYINDNRRgpapksa 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 333 --------------------------QVQGASIILDPKTGGVRAVVG----NRGEhtflgFNYATQLRNSPGSTIKPLmV 382
Cdd:COG5009 394 sdvlkpgdvirvrpvadggwrlrqipEVQGALVALDPHTGAVLALVGgfdfEQSK-----FNRATQAKRQPGSSFKPF-V 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 383 YTPALENGYHYDSILKDEKLSY----GKNNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQ 458
Cdd:COG5009 468 YAAALDNGYTPATIINDAPIVFddggGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIY 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 459 lKSSDQNLAAALG-GlknGVSPLMLARAYAAFANDGKLPTTHFIRKIVDASGETV----------------VDNSHPAT- 520
Cdd:COG5009 548 -SKLPPNLSLALGsG---EVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIyradparacedcdaaeWDGAEPRLp 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 521 ---RQIMSKKVAQEMTSMMIGTFNEGTGKTAKPSGYTIAGKTGSTEvpsswgyGTKDQWVVGYTPDIVNATWIGYpttDS 597
Cdd:COG5009 624 dpaEQVIDPRTAYQMTSMLRGVVQRGTGRRARALGRDIAGKTGTTN-------DSKDAWFVGFTPDLVAGVWVGF---DD 693
|
730 740 750
....*....|....*....|....*....|....
gi 491946630 598 QHFLQGTSTSGVA--PLFKLEMSKLMPNTPQTAF 629
Cdd:COG5009 694 PRSLGRGETGGRAalPIWIDFMKAALKDKPEKPF 727
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
10-643 |
4.54e-104 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 334.11 E-value: 4.54e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 10 SIRWFFRRFQVIRWLILLGLTVILIFSAWFTYKAKTADvqnikstlQTKTVIYDANNEEAGTLYGQKGTY---VELSAIS 86
Cdd:COG4953 3 RARLRRRRLLALLLALLLLALALWALDRLFPLPLLFAV--------PYSTVVLDRDGTLLRAFLAADGQWrlpVPLDEVS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 87 PQVQNAVISTEDRTFYSNGGFSIKGILRSALNYvIHHGQIMGGGSTITQQLAKntLLTQKQ-TMLRKAQELFMAIQLNKV 165
Cdd:COG4953 75 PRYLQALLAYEDRRFYYHPGVNPLALLRAAWQN-LRSGRIVSGGSTLTMQVAR--LLEPRPrTLSGKLRQILRALQLERR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 166 YSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVLQLMVDNH 245
Cdd:COG4953 152 YSKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 246 kltqaqanaakaqsvqVVDAfsnanaqkypsyfdSVIEEARSEGIS-------------VDDILN---KGYKIYTNLDqt 309
Cdd:COG4953 232 ----------------VIDA--------------EEAALALLEPVParrrplpqlaphlARRLLRqlpGGTRIRTTLD-- 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 310 yqQNLQTSFEQ---DWAfpANAADGKQVQGASIILDPKTGGVRAVVGNRGEH--TFLGFNYATQLRNSPGSTIKPLmVYT 384
Cdd:COG4953 280 --AGLQRRLERlvrRYV--RRLKQNGIHNAAVLVVDNRTGEVLAYVGSADFFdaSRQGQVDMVRALRSPGSTLKPF-LYG 354
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 385 PALENGY-HYDSILKDEKLSYGknNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQ--LKS 461
Cdd:COG4953 355 LALDQGLiHPETLLADVPTSFG--GYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRllLPP 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 462 SDQ-NLAAALGGLknGVSPLMLARAYAAFANDGKLPTTHFIRkivdasgetvvDNSHPATRQIMSKKVAQEMTSMMIGTF 540
Cdd:COG4953 433 AEHyGLSLILGGA--EVTLEELVGLYAALARGGEARPLRLLA-----------GEPASPGRRLLSPGAAWLVRDILSDVP 499
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 541 --NEGTGKTAKPSGYTIAGKTGsTevpsSWGYgtKDQWVVGYTPDIVNATWIGYPttDsqhflqGTSTSGV------APL 612
Cdd:COG4953 500 rpDGAFGWRALDSPPPIAWKTG-T----SYGF--RDAWAVGFTGRYTVGVWVGNP--D------GTPVPGLtgaeaaAPL 564
|
650 660 670
....*....|....*....|....*....|.
gi 491946630 613 FKLEMSKLMPNTPQTAFDTKDAAQMASIQTP 643
Cdd:COG4953 565 LFDIFDLLPASRWPLPFPPPAGLLRVEVCAP 595
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
70-624 |
3.59e-88 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 291.24 E-value: 3.59e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 70 GTLYGQKGT---YVELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSALnYVIHHGQIMGGGSTITQQLAKNTLLTQK 146
Cdd:TIGR02071 137 AMLYSPNGEqrlFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVW-VNLTAGRTVQGGSTLTQQLVKNLFLSNE 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 147 QTMLRKAQELFMAIQLNKVYSKQDILAMYLNNAYFG----NGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYN 222
Cdd:TIGR02071 216 RSLWRKANEAYMALILDARYSKDRILELYLNEVYLGqsgdDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYN 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 223 PADHKDNAISRRNVVLQLMVDNHKLTQAQANAAKAQSVQVVDAFSNANaqKYPSYFDSVIEEARSEgiSVDDILN-KGYK 301
Cdd:TIGR02071 296 PWRNPDRALERRNLVLRLLQEQKIIDDEEYDMLSARPLGVQKKGGIIS--RQPAFLQLVRRELRQK--LGDKVKDlSGLR 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 302 IYTNLDQTYQQNLQTSFEQDWAFPANAADGKQVQGASIILDPKTGGVRAVVGNRgEHTFLGFNYATQLRNSPGSTIKPlM 381
Cdd:TIGR02071 372 IFTTLDPVSQSAAEQAVQETIPALKKKKKLPDLEAAMVVTDRFTGEVRAMVGGS-DPQFAGFNRALQARRQIGSLVKP-A 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 382 VYTPALEN--GYHYDSILKDEKLSYGKNN---YTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFG 456
Cdd:TIGR02071 450 VYLTALSQpdKYRLNTWIEDQPLSIKLSNgqvWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLG 529
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 457 IQLKSSDQNLAAALGGLKngVSPLMLARAYAAFANDGKLPTTHFIRKIVDASGeTVVDNSHPATRQIMSKKVAQEMTSMM 536
Cdd:TIGR02071 530 INKDEIPPVPSMLLGAIN--LTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDG-KVLYQSDPQAEQAVPSQAAYLTLYAM 606
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 537 IGTFNEGTGKT--AKPSGYTIAGKTGSTEvpsswgyGTKDQWVVGYTPDIVNATWIGyptTDSQHFLQGTSTSGVAPLFK 614
Cdd:TIGR02071 607 QQVVQRGTARSlgADFPSLSLAGKTGTTN-------DNRDSWFAGIDGKEVTIIWLG---RDDNGPTKLTGASGALQVYA 676
|
570
....*....|
gi 491946630 615 LEMSKLMPNT 624
Cdd:TIGR02071 677 RYLSYQTPEP 686
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
59-657 |
6.03e-84 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 279.69 E-value: 6.03e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 59 TVIYDANNEEAGTLYGQKGTY---VELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSALNYVIHhGQIMGGGSTITQ 135
Cdd:TIGR02073 12 TVVLDRHGTLLRALLANDGQWrlpVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTN-GRRVSGGSTLTM 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 136 QLAKNTLLTQKQTMLRKAQELFMAIQLNKVYSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGML 215
Cdd:TIGR02073 91 QLARLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALP 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 216 RNPSYYNPADHKDNAISRRNVVLQLMVDNHkltqaqanaakaqsvqVVDAFSNANAQKYPsyfdSVIEEARSEGIS---V 292
Cdd:TIGR02073 171 QAPSARRLDRLPKAAKAARDRLLDRMVEQG----------------PDDSEQVALAALEP----LPALPEPLPQLAphfA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 293 DDILNKGYKIYTNLDQTYQQNLQTSFE---QDWAFpANAADGKQvQGASIILDPKTGGVRAVVGNRGEHTFLGFNY--AT 367
Cdd:TIGR02073 231 LKLLRARPEIASVIVSTLDADLQRRLEelaRRYLS-ALRPRGIS-NLAILVVDNRSGAVLAYVGSADFFDDSNSGQvdGV 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 368 QLRNSPGSTIKPLmVYTPALENGY-HYDSILKDEKLSYGknNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQ 446
Cdd:TIGR02073 309 RAPRSPGSTLKPF-LYALALDDGLlHPDSLLKDVPLRFG--DYAPENFDKTFHGPVPAREALARSLNIPAVRLLERVGPP 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 447 KGVASLDRFGIQLKSSDQ---NLAAALGGlkNGVSPLMLARAYAAFANDGklpTTHFIRkivdasgETVVDNSHPATRQI 523
Cdd:TIGR02073 386 RFADFLRQAGLNLLKPKSdyyGLSLALGG--AEITLQDLANLYAMLANQG---LSGPLR-------FLQTDAKRPERERL 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 524 MSKKVAQEMTSMMIGTFNEGT--GKTAKPSGYTIAGKTGstevpSSWGYgtKDQWVVGYTPDIVNATWIGYPTtdsqhfl 601
Cdd:TIGR02073 454 LSPGAAWIVLDILKDRPRPDDtlPLSALPTRLPLAWKTG-----TSYGF--RDAWAAGVSGRYTIGVWVGNFD------- 519
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491946630 602 qGTSTSGV------APLFklemsklmpntpqtaFDTKDAAQMASIQTPGKSDDTWQGIQDSI 657
Cdd:TIGR02073 520 -GKPNPGFfgaaaaAPLL---------------FDILDALQASEASTLPRPLKEVPGCLVLG 565
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
65-242 |
4.21e-83 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 259.76 E-value: 4.21e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 65 NNEEAGTLYGQKGTYVELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSALNyVIHHGQIMGGGSTITQQLAKNTLLT 144
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLS-NLRSGRIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 145 QKQTMLRKAQELFMAIQLNKVYSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPA 224
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 491946630 225 DHKDNAISRRNVVLQLMV 242
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
21-611 |
1.99e-63 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 225.78 E-value: 1.99e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 21 IRWLILLGLTVIL-----IFSAWFTYKAKTADVQNIKST-LQTKTVIYDANNEEAGTlYGQKGTY-VELSAISPQVQNAV 93
Cdd:PRK11636 4 VKYLLILAVCCILlgagsIYGLYRYIEPQLPDVATLKDVrLQTPMQVYSADGELIAQ-YGEKRRIpLTLDQIPPEMVKAF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 94 ISTEDRTFYSNGGFSIKGILRSAlNYVIHHGQIMGGGSTITQQLAKNTLLTQKQTMLRKAQELFMAIQLNKVYSKQDILA 173
Cdd:PRK11636 83 IATEDSRFYEHHGVDPVGIFRAA-SVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 174 MYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVLQLMVDNHKLTQAqan 253
Cdd:PRK11636 162 LYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQA--- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 254 aakaqsvQVVDAFSNANAQKY--PSYFDS---VIEEARSEGISV--DDILNKGYKIYTNLDQTYQQNLQTSF-------- 318
Cdd:PRK11636 239 -------QYDQARSEPIVANYhaPEIAFSapyLSEMVRQEMYNRygENAYEDGYRVYTTITRKVQQAAQQAVrnnvldyd 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 319 ----------------EQDWA-----------------FPA-----NA-------ADGKQV------------------Q 335
Cdd:PRK11636 312 mrhgyrgpanvlwkvgESAWDnkkitdtlkalptygplLPAvvtsaNPqeatamlADGSSValpmegvrwarpyrsdtqQ 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 336 GAS-----------------------------------IILDPKTGGVRAVVG----NRGEhtflgFNYATQLRNSPGST 376
Cdd:PRK11636 392 GPTprkvtdvvqtgqqiwvrqvddawwlaqvpdvnsalVSINPQNGAVMALVGgfdfNQSK-----FNRATQALRQVGSN 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 377 IKPLMvYTPALENGYHYDSILKDEKLSY----GKNNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASL 452
Cdd:PRK11636 467 IKPFL-YTAAMDKGLTLASMLNDVPISRwdagAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYL 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 453 DRFGIQLKSSDQNLAAALGGlkNGVSPLMLARAYAAFANDGKLPTTHFIRKIVDASGETV-------------------- 512
Cdd:PRK11636 546 QRFGFPAQNIVHTESLALGS--ASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIfeakpkvacpecdipviygd 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 513 --------------VDNSH-------------PATRQIMSKKVAQEMTSMMIGT--------------FNE----GTGKT 547
Cdd:PRK11636 624 tqksnvlenddvenVATSQeqqnssvpmpqleQANQALVAQNGAQEYAPHVINTplafliksalntniFGEpgwmGTGWR 703
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491946630 548 AKP--SGYTIAGKTGSTEvpSSwgygtKDQWVVGYTPDIVNATWIGYptTDSQHFLQGTSTSGVAP 611
Cdd:PRK11636 704 AGRdlKRRDIGGKTGTTN--SS-----KDAWFSGYGPGVVTSVWIGF--DDHRRDLGRTTASGAIK 760
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
74-622 |
4.84e-60 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 215.09 E-value: 4.84e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 74 GQKGTYVELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSALNYVIHhGQIMGGGSTITQQLAKNTLLTQKQTMLRKA 153
Cdd:PRK14850 154 GKKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMS-GHTIQGGSTLTQQLVKNLFLTNTRSLWRKI 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 154 QELFMAIQLNKVYSKQDILAMYLNNAYFG-NG---VWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDN 229
Cdd:PRK14850 233 NEIYMALILDRFYSKDRILELYLNEVYLGqDGneqIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNL 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 230 AISRRNVVLQLMVDNHKLTQAQANAAKAQSVQVVdafSNANA-QKYPSYFDSVIEEARSE-GISVDDIlnKGYKIYTNLD 307
Cdd:PRK14850 313 TLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNVQ---SKGNIiSSHPAFIQLVCEEFHKKiHYPFKNF--SGTKIFTTLD 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 308 QTYQQNLQTSFEQDWAFPANAADGKQVQGASIILDPKTGGVRAVVGNRGEHtFLGFNYATQLRNSPGSTIKPLmVYTPAL 387
Cdd:PRK14850 388 YISQNAAEQAVKIGIPILKRKKRLKDLEVAMVIIDRFSGEVRALIGSSKPE-FNGYNRALKARRSIGSLSKPI-TYLTAL 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 388 E--NGYHYDSILKDEKLSYGKNN---YTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQLKSS 462
Cdd:PRK14850 466 SqpEKYHLNTWISDTPISIKLDNgqyWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSNYI 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 463 DQNLAAALGGLKngVSPLMLARAYAAFANDGKLPTTHFIRKIVDASGEtVVDNSHPATRQIMSKKVAQEMTSMMIGTFNE 542
Cdd:PRK14850 546 TPLPSISLGAIN--LTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNK-VLYQNFPQSKHVESSQASYLTLYAMQQVVKS 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 543 GTGKT--AKPSGYTIAGKTGSTEvpsswgyGTKDQWVVGYTPDIVNATWIGyptTDSQHFLQGTSTSGVAPLFK--LEMS 618
Cdd:PRK14850 623 GTAKSlgTIFKEFSLAGKTGTTN-------NLVDSWFVGIDGKQVVITWIG---RDNNHTTKLYGSSGAMKIYKryLQYQ 692
|
....
gi 491946630 619 KLMP 622
Cdd:PRK14850 693 NPVP 696
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
91-591 |
3.21e-58 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 210.78 E-value: 3.21e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 91 NAVISTEDRTFYSNGGFSIKGILRSALNYVIHhGQIMGGGSTITQQLAKNTLLTQKQTMLRKAQELFMAIQLNKVYSKQD 170
Cdd:PRK09506 225 DTLLATEDRHFYEHDGISLYSIGRAVLANLTA-GRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 171 ILAMYLNNAYFG----NGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVLQLMVDNHK 246
Cdd:PRK09506 304 ILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQI 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 247 LTQAQANAAKAQSVQVVDAFSNANAQkyPSYFDSVIEEARSE-GISVDDIlnKGYKIYTNLDQTYQQNLQTSFEQDWAFP 325
Cdd:PRK09506 384 IDQELYDMLSARPLGVQPKGGVISPQ--PAFMQMVRQELQAKlGDKVKDL--SGVKIFTTLDPVSQDAAEKAVEEGIPAL 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 326 ANAADGKQVQGASIILDPKTGGVRAVVGNrGEHTFLGFNYATQLRNSPGSTIKPlMVYTPALE--NGYHYDSILKDEKLS 403
Cdd:PRK09506 460 KKQRKLSDLETAMVVVDRFSGEVRAMVGG-SEPQFAGYNRAMQARRSIGSLAKP-ATYLTALSqpDKYRLNTWIADAPIS 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 404 YGKNN---YTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQLKSSDQNLAAALGGLknGVSPL 480
Cdd:PRK09506 538 LRQPNgqvWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPAMLLGAL--NLTPI 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 481 MLARAYAAFANDGKLPTTHFIRKIVDASGeTVVDNSHPATRQIMSKKVAQEMTSMMIGTFNEGTGK--TAKPSGYTIAGK 558
Cdd:PRK09506 616 EVAQAFQTIASGGNRAPLSALRSVIAEDG-KVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRGTGRqlGAKYPNLHLAGK 694
|
490 500 510
....*....|....*....|....*....|...
gi 491946630 559 TGSTEvpsswgyGTKDQWVVGYTPDIVNATWIG 591
Cdd:PRK09506 695 TGTTN-------DLVDSWFAGIDGKEVTITWVG 720
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
80-593 |
2.72e-43 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 167.18 E-value: 2.72e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 80 VELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRSA-LNyvIHHGQIMGGGSTITQQLAKntLLT-QKQTMLRKAQELF 157
Cdd:PRK11240 65 VTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAwQD--LTSGRVISGGSTLTMQVAR--LLDpHPRTFGGKIRQLW 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 158 MAIQLNKVYSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVV 237
Cdd:PRK11240 141 RALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKV 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 238 LQLMVDNHKLTQAqanaakaqsvQVVDA-------FSNANAQKYPSYFDSVIEEARSEgisvddilnkgyKIYTNLDQTY 310
Cdd:PRK11240 221 LERMAEQGVWSAE----------QVKESreepvwlAPRQMPQLAPLFARMMLGKSKSD------------KIVTTLDAGL 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 311 QQNLQtSFEQDWA--FPANAAdgkqvqGASIILDPKTGGVRAVVGN---RGEHTFLGFNYATQLRnSPGSTIKPLmVYTP 385
Cdd:PRK11240 279 QRRLE-DLALNWKgrLPPRSS------LAMIVVDHTDMAVRGWVGSvdlNDDSRFGHVDMVNAIR-SPGSVLKPF-VYGL 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 386 ALENGY-HYDSILKDEKLSYGknNYTPTNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGIQLK---S 461
Cdd:PRK11240 350 ALDDGLiHPASLLQDVPRRTG--DYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYlpaG 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 462 SDQNLAAALGGlkNGVSPLMLARAYAAFANDGKLPTTHFirkivdASGETVVDnshpatRQIMSKKVAQEMTSMMIGtfn 541
Cdd:PRK11240 428 AEPNLSLILGG--AGARLEDMVAAYSAFARHGKAAKLRL------QPDDPLLE------RPLMSPGAAWIIRRIMAD--- 490
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 491946630 542 EGTGK--TAKPSGYTIAGKTGSTevpsswgYGTKDQWVVGYTPDIVNATWIGYP 593
Cdd:PRK11240 491 EAQPLpdAALPRVVPLAWKTGTS-------YGYRDAWAIGVNARYVIGIWTGRP 537
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
299-582 |
7.24e-40 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 154.60 E-value: 7.24e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 299 GYKIYTNLDQTYQQNLQTSFEQdwAFPANAADGkqvqGASIILDPKTGGVRAVVGN---------RGEHTFLgFNYATQL 369
Cdd:COG0768 218 GKDLVLTIDSDLQKIAEEALKK--AVEEYKAKS----GAVVVMDPKTGEILAMASYpsfdpnlfvGGPDEPL-RNRAVQG 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 370 RNSPGSTIKPLMVYTpALENG-YHYDSILKDE-KLSYGKNNYTPTNATGTylGTVPMYQALADSINAPAVWLLNKLGVQK 447
Cdd:COG0768 291 TYEPGSTFKPFTAAA-ALEEGvITPDTTFDCPgYYRVGGRTIRDWDRGGH--GTLTLTEALAKSSNVGFYKLALRLGIDK 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 448 GVASLDRFGI--------------QLKSSDQ----NLA-AALG-GLKngVSPLMLARAYAAFANDGKLPTTHFIRKIVDA 507
Cdd:COG0768 368 LYDYLKKFGLgqktgidlpgeasgLLPSPKRwypgETAtMSIGqGLS--VTPLQLAQAYAAIANGGVLVKPHLVKEIVDP 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 508 SGETVVDNSHPAtRQIMSKKVAQEMTSMMIGTFNE--GTGKTAKPSGYTIAGKTGSTEVPSSWGYGTKDQ----WVVGYT 581
Cdd:COG0768 446 DGEVVKEEPEVL-RRVISPETAETVREGMEGVVNEpgGTARRAAIPGYRVAGKTGTAQVVDIGNGGYYKGrhiaSFVGFA 524
|
.
gi 491946630 582 P 582
Cdd:COG0768 525 P 525
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
79-221 |
1.14e-36 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 137.21 E-value: 1.14e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 79 YVELSAISPQVQNAVISTEDRTFYSNGGFSIKGILRsALNYVIHHGQIMGGGSTITQQLAKNTLLTQKQTMLRKAQELFM 158
Cdd:TIGR02070 57 WRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQD-ALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWA 135
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491946630 159 AIQLNKVYSKQDILAMYLNNAYFGNGVWGVQDAAKRYFGKNASQLDASEGAILAGMLRNPSYY 221
Cdd:TIGR02070 136 TWMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYY 198
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
25-241 |
1.04e-32 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 126.07 E-value: 1.04e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 25 ILLGLTVILIFSAWFTYKAKTADVQNIKstlqtktviydanneeagtlygQKGTYVELSAISPQVQNAVISTEDRTFYSN 104
Cdd:PRK13481 15 ILIIIALFIGIMYFLSTRDNVDELRKIE----------------------NKSSFVSADNMPEYVKGAFISMEDERFYKH 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 105 GGFSIKGILRsALNYVIHHGQIMGGgSTITQQLAKNTLLTQKQTMLRKAQELFMAIQLNKVYSKQDILAMYLNNAYFGNG 184
Cdd:PRK13481 73 HGFDLKGTTR-ALFSTISDRDVQGG-STITQQVVKNYFYDNERSFTRKVKELFVAHRVEKQYSKNEILSFYLNNIYFGDN 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491946630 185 VWGVQDAAKRYFG-------KNASQLDASEGAILAGMLRNPSYYNPADHKDNAISRRNVVLQLM 241
Cdd:PRK13481 151 QYTLEGAANHYFGttvnknsTTMSHITVLQSAILASKVNAPSVYNINDMSENFTQRVSTNLEKM 214
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
336-614 |
7.95e-32 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 125.61 E-value: 7.95e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 336 GASIILDPKTGGVRAVVGNRgehTFLGFNYATQLRN-------SPGSTIKPLMVyTPALENG-YHYDSILKDEKLSYGKN 407
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKP---SYDPNGFIGPLRNravtsryEPGSTFKPFTA-LAALDNGvLKPDETIFDWPGKQQGG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 408 NYTPtNATGTYLGTVPMYQALADSINAPAVWLLNKLGVQKGVASLDRFGI----------------QLKSSDQNLAAALG 471
Cdd:pfam00905 77 KSIG-DWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgnktgiglpgenagylTPYWLEGATASFGI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491946630 472 GLKngVSPLMLARAYAAFANDGKLPTTHFIRKIVDAsgetvvDNSHPATRQIMSKKVAQEMTSMMIGTFNEGTGK-TAKP 550
Cdd:pfam00905 156 GLT--ITPLQQAQAYAAIANGGKLVPPHLVKSIEDK------VDPKVLNKLPISKSTAEKVKDMLRLVVNDGTGTgTAAV 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491946630 551 SGYTIAGKTGSTEV----PSSWGYGTKDQWVVGYTPDiVNATWIGYPTTDSQHFLQGTSTSgvAPLFK 614
Cdd:pfam00905 228 PGYKVAGKTGTAQVagpkGGGYYDGAQIGWFVGYAPA-DNPKYAFAVLIDDPKRYYGGKVA--APIFK 292
|
|
| |
