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Conserved domains on  [gi|492088678|ref|WP_005744256|]
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MULTISPECIES: methyl-accepting chemotaxis protein [Pseudomonas syringae group]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
34-426 1.45e-73

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 244.93  E-value: 1.45e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  34 ALLYWVALNIRSDIMLQLHGTQLDAAELGKIQGQLDVLSNAILLSTLFTLVMVSFMVWYFRHLIVRPVMFMTHALEEIAn 113
Cdd:COG0840  143 LALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIA- 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 114 gEGDLSRDLPLLTHDEIRVLASTCNRFLAKQREVISSIQALTVQIAVESARSLKNISDSSDSATDQARFAREVMDQSNMA 193
Cdd:COG0840  222 -EGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEEL 300

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 194 VGSIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNISQISSSLNEFGGLVSGLNERSSSIKSIVGLIQQISSQTNLL 273
Cdd:COG0840  301 SATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLL 380

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 274 ALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEVSSTHEQTIQISHSARETQQVVERASGHFES 353
Cdd:COG0840  381 ALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEE 460

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492088678 354 MIGDFESTNDKLADIAAHIQQFATTNTGINERVTRIYSDSQAIDQRMQHSATATRDLSGVAEKVQALLGRFVL 426
Cdd:COG0840  461 IVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
34-426 1.45e-73

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 244.93  E-value: 1.45e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  34 ALLYWVALNIRSDIMLQLHGTQLDAAELGKIQGQLDVLSNAILLSTLFTLVMVSFMVWYFRHLIVRPVMFMTHALEEIAn 113
Cdd:COG0840  143 LALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIA- 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 114 gEGDLSRDLPLLTHDEIRVLASTCNRFLAKQREVISSIQALTVQIAVESARSLKNISDSSDSATDQARFAREVMDQSNMA 193
Cdd:COG0840  222 -EGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEEL 300

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 194 VGSIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNISQISSSLNEFGGLVSGLNERSSSIKSIVGLIQQISSQTNLL 273
Cdd:COG0840  301 SATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLL 380

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 274 ALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEVSSTHEQTIQISHSARETQQVVERASGHFES 353
Cdd:COG0840  381 ALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEE 460

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492088678 354 MIGDFESTNDKLADIAAHIQQFATTNTGINERVTRIYSDSQAIDQRMQHSATATRDLSGVAEKVQALLGRFVL 426
Cdd:COG0840  461 IVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 169-424 2.97e-50

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 174.40  E-value: 2.97e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678   169 ISDSSDSATDQARFAREVMDQSNMAVGSIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNISQISSSLNEFGGLVSG 248
Cdd:smart00283   6 VEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSAVEE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678   249 LNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEVSSTHE 328
Cdd:smart00283  86 LEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNEAVA 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678   329 QTIQISHSARETQQVVERASGHFESMIGDFESTNDKLADIAAHIQQFATTNTGINERVTRIYSDSQAIDQRMQHSATATR 408
Cdd:smart00283 166 AMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEISAAAE 245

                          250
                   ....*....|....*.
gi 492088678   409 DLSGVAEKVQALLGRF 424
Cdd:smart00283 246 ELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 196-378 1.21e-41

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 149.31  E-value: 1.21e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 196 SIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNISQISSSLNEFGGLVSGLNERSSSIKSIVGLIQQISSQTNLLAL 275
Cdd:cd11386    6 SIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQTNLLAL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 276 NAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEVSSTheqtiqiSHSARETQQVVERASGHFESMI 355
Cdd:cd11386   86 NAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEA-------VEAMEETSEEVEEGVELVEETG 158

                        170       180
                 ....*....|....*....|...
gi 492088678 356 GDFESTNDKLADIAAHIQQFATT 378
Cdd:cd11386  159 RAFEEIVASVEEVADGIQEISAA 181
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 249-393 2.12e-27

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 108.67  E-value: 2.12e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  249 LNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEvssTHE 328
Cdd:pfam00015  28 IAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQ---TND 104

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492088678  329 QTIQISHSARETQQ---VVERASGHFESMIGDFESTNDKLADIAAHIQQFATTNTGINERVTRIYSDS 393
Cdd:pfam00015 105 STASIESTRQRVEVgstIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVARMDQVT 172
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
65-426 8.36e-24

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 105.54  E-value: 8.36e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  65 QGQLDVLSNAILLSTLFTL--VMVSFMVWYFRHLIVRPVMFMTHALEEIAngEGDLSRDLPLLTHDEIRVLASTCNRFLA 142
Cdd:PRK09793 180 QSQRNYQISALVFISMIIVaaIYISSALWWTRKMIVQPLAIIGSHFDSIA--AGNLARPIAVYGRNEITAIFASLKTMQQ 257

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 143 KQREVISSI----QALTVQIAVESARSLKNISDSSDSATDQARFAREvMDQSNMAVGSIEDVSQQTQGISTTTAQNLSMA 218
Cdd:PRK09793 258 ALRGTVSDVrkgsQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAAS-MEQLTATVGQNADNARQASELAKNAATTAQAG 336

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 219 RDSYAElleVTGNISQISSSlnefgglvsglnerSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEV 298
Cdd:PRK09793 337 GVQVST---MTHTMQEIATS--------------SQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV 399

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 299 RTLAQNVSKATDDISRNIDamlQEVSSTHEQTIQISHSARETQQVVERASghfesmigdfeSTNDKLADIAAHIQQfatT 378
Cdd:PRK09793 400 RNLASRSAQAAKEIKGLIE---ESVNRVQQGSKLVNNAAATMTDIVSSVT-----------RVNDIMGEIASASEE---Q 462

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
gi 492088678 379 NTGInERVTRIYSDSQAIDQR----MQHSATATRDLSGVAEKVQALLGRFVL 426
Cdd:PRK09793 463 RRGI-EQVAQAVSQMDQVTQQnaslVEEAAVATEQLANQADHLSSRVAVFTL 513
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
34-426 1.45e-73

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 244.93  E-value: 1.45e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  34 ALLYWVALNIRSDIMLQLHGTQLDAAELGKIQGQLDVLSNAILLSTLFTLVMVSFMVWYFRHLIVRPVMFMTHALEEIAn 113
Cdd:COG0840  143 LALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIA- 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 114 gEGDLSRDLPLLTHDEIRVLASTCNRFLAKQREVISSIQALTVQIAVESARSLKNISDSSDSATDQARFAREVMDQSNMA 193
Cdd:COG0840  222 -EGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEEL 300

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 194 VGSIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNISQISSSLNEFGGLVSGLNERSSSIKSIVGLIQQISSQTNLL 273
Cdd:COG0840  301 SATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLL 380

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 274 ALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEVSSTHEQTIQISHSARETQQVVERASGHFES 353
Cdd:COG0840  381 ALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEE 460

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492088678 354 MIGDFESTNDKLADIAAHIQQFATTNTGINERVTRIYSDSQAIDQRMQHSATATRDLSGVAEKVQALLGRFVL 426
Cdd:COG0840  461 IVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 169-424 2.97e-50

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 174.40  E-value: 2.97e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678   169 ISDSSDSATDQARFAREVMDQSNMAVGSIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNISQISSSLNEFGGLVSG 248
Cdd:smart00283   6 VEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSAVEE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678   249 LNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEVSSTHE 328
Cdd:smart00283  86 LEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNEAVA 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678   329 QTIQISHSARETQQVVERASGHFESMIGDFESTNDKLADIAAHIQQFATTNTGINERVTRIYSDSQAIDQRMQHSATATR 408
Cdd:smart00283 166 AMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEISAAAE 245

                          250
                   ....*....|....*.
gi 492088678   409 DLSGVAEKVQALLGRF 424
Cdd:smart00283 246 ELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 196-378 1.21e-41

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 149.31  E-value: 1.21e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 196 SIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNISQISSSLNEFGGLVSGLNERSSSIKSIVGLIQQISSQTNLLAL 275
Cdd:cd11386    6 SIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQTNLLAL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 276 NAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEVSSTheqtiqiSHSARETQQVVERASGHFESMI 355
Cdd:cd11386   86 NAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEA-------VEAMEETSEEVEEGVELVEETG 158

                        170       180
                 ....*....|....*....|...
gi 492088678 356 GDFESTNDKLADIAAHIQQFATT 378
Cdd:cd11386  159 RAFEEIVASVEEVADGIQEISAA 181
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 249-393 2.12e-27

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 108.67  E-value: 2.12e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  249 LNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEvssTHE 328
Cdd:pfam00015  28 IAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQ---TND 104

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492088678  329 QTIQISHSARETQQ---VVERASGHFESMIGDFESTNDKLADIAAHIQQFATTNTGINERVTRIYSDS 393
Cdd:pfam00015 105 STASIESTRQRVEVgstIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVARMDQVT 172
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
65-426 8.36e-24

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 105.54  E-value: 8.36e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  65 QGQLDVLSNAILLSTLFTL--VMVSFMVWYFRHLIVRPVMFMTHALEEIAngEGDLSRDLPLLTHDEIRVLASTCNRFLA 142
Cdd:PRK09793 180 QSQRNYQISALVFISMIIVaaIYISSALWWTRKMIVQPLAIIGSHFDSIA--AGNLARPIAVYGRNEITAIFASLKTMQQ 257

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 143 KQREVISSI----QALTVQIAVESARSLKNISDSSDSATDQARFAREvMDQSNMAVGSIEDVSQQTQGISTTTAQNLSMA 218
Cdd:PRK09793 258 ALRGTVSDVrkgsQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAAS-MEQLTATVGQNADNARQASELAKNAATTAQAG 336

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 219 RDSYAElleVTGNISQISSSlnefgglvsglnerSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEV 298
Cdd:PRK09793 337 GVQVST---MTHTMQEIATS--------------SQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV 399

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 299 RTLAQNVSKATDDISRNIDamlQEVSSTHEQTIQISHSARETQQVVERASghfesmigdfeSTNDKLADIAAHIQQfatT 378
Cdd:PRK09793 400 RNLASRSAQAAKEIKGLIE---ESVNRVQQGSKLVNNAAATMTDIVSSVT-----------RVNDIMGEIASASEE---Q 462

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
gi 492088678 379 NTGInERVTRIYSDSQAIDQR----MQHSATATRDLSGVAEKVQALLGRFVL 426
Cdd:PRK09793 463 RRGI-EQVAQAVSQMDQVTQQnaslVEEAAVATEQLANQADHLSSRVAVFTL 513
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 65-364 3.52e-22

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 100.47  E-value: 3.52e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  65 QGQLDVLSnaillstlFTLVMVSFMVWY-FRHLIVRPVMFMTHALEEIANGegDLSRDLPLLTHDEIRVLASTCNRFlak 143
Cdd:PRK15048 191 QWQLAVIA--------LVVVLILLVAWYgIRRMLLTPLAKIIAHIREIAGG--NLANTLTIDGRSEMGDLAQSVSHM--- 257

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 144 QREVIssiqaltvqiavESARSLKNISDSSDSATDQ-ARFAREVMDQSNMAVGSIEDVSQQTQGISTTTAQNLSMARDSy 222
Cdd:PRK15048 258 QRSLT------------DTVTHVREGSDAIYAGTREiAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQA- 324

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 223 AELLEVTGNISQISSSLNEfgGLVSGLNE---RSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVR 299
Cdd:PRK15048 325 SQLAQSASDTAQHGGKVVD--GVVKTMHEiadSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVR 402

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492088678 300 TLAQNVSKAtddiSRNIDAMLQEVSSTHEQTIQISHSARETQQVVERASGHFESMIGDFESTNDK 364
Cdd:PRK15048 403 NLASRSAQA----AKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDE 463
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
75-423 3.23e-20

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 94.25  E-value: 3.23e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  75 ILLSTLFTLVMVSFMVWY-FRHLIVRPVMFMTHALEEIANGegDLSRDLPLLTHDEIRVLASTCNRFlakQREVISSIQa 153
Cdd:PRK15041 195 ILVGVMIVVLAVIFAVWFgIKASLVAPMNRLIDSIRHIAGG--DLVKPIEVDGSNEMGQLAESLRHM---QGELMRTVG- 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 154 ltvqiavesarSLKNISDSSDS-ATDQARFAREVMDQSNMAVGSIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNI 232
Cdd:PRK15041 269 -----------DVRNGANAIYSgASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETA 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 233 SQISSSLNEFGGLVSGLNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKAtddi 312
Cdd:PRK15041 338 QRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQA---- 413

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 313 SRNIDAMLQEVSSTHEQTIQISHSARETQQVVERASGHFESMIGDFESTNDK-----------LADI-------AAHIQQ 374
Cdd:PRK15041 414 AREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEqsrgidqvglaVAEMdrvtqqnAALVEE 493

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 492088678 375 FATTNTGINERVTRIysdSQAIDQ-RMQHSATATRDLSGVAEKVQALLGR 423
Cdd:PRK15041 494 SAAAAAALEEQASRL---TEAVAVfRIQQQQQQQRETSAVVKTVTPATPR 540
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 75-158 2.24e-07

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 53.43  E-value: 2.24e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  75 ILLSTLFTLVMVSFMVW---YFRHLIVRPVMFMTHALEEIAngEGDLSRDLPLLTHDEIRVLASTCNRF---LAKQREVI 148
Cdd:COG5000    8 LLLLLLIALLLLLLALWlalLLARRLTRPLRRLAEATRAVA--AGDLSVRLPVTGDDEIGELARAFNRMtdqLKEQREEL 85

                         90
                 ....*....|
gi 492088678 149 SSIQALTVQI 158
Cdd:COG5000   86 EERRRYLETI 95
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 34-368 3.81e-07

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 52.96  E-value: 3.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  34 ALLYWVALNIRSDIMLQLHGTQLDAAELGKIQGQLDVLSNAILLSTLFTLVMVSFMVWYFRHLIVRPVMFMTHALEEIAn 113
Cdd:COG3850   79 LLLLLLLLAALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIA- 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 114 gEGDLSRDLPLLTHDEIRVLASTCNRFLAKQREVISSIQALTVQIAVESARSLKNISDSSDSATDQARFAREVMDQSNMA 193
Cdd:COG3850  158 -RGDFDARVPVSGRDELGTLARAFNRMADELQELYAELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLA 236

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 194 VGSIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNISQISSSLNEFGGLVSGLNERSSSIKSIVGLIQQISSQTNLL 273
Cdd:COG3850  237 ALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLL 316

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 274 ALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEVSSTHEQTIQISHSARETQQVVERASGHFES 353
Cdd:COG3850  317 LLLLQAIANASLLLIALASVVAALLELASILALQAALEAAAAGAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGA 396

                        330
                 ....*....|....*
gi 492088678 354 MIGDFESTNDKLADI 368
Cdd:COG3850  397 AGQGAGLVDVEGGVA 411
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
34-467 3.40e-05

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 47.03  E-value: 3.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  34 ALLYWVALNIRSDIMLQLHGTQLDAAELGKIQGQLDVLSNAILLSTLFTLVMVSFMVWYFRHLIVRPVMFMTHALEEIAn 113
Cdd:COG2770  173 LLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIA- 251

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 114 gEGDLSRDLPLLTHDEIRVLASTCNRFLAKQREVISSIQALTVQIAVESARSLKNISDSsdSATDQARFAREVMDQSNMA 193
Cdd:COG2770  252 -AGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLEL--LLALLLLLLALLLLAAAAL 328

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 194 VGSIEDVSQQTQGISTTTAQNLSMARDSYAELLEVTGNISQISSSLNEFGGLVSGLNERSSSIKSIVGLIQQISSQTNLL 273
Cdd:COG2770  329 LLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELA 408

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 274 ALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAMLQEVSSTHEQTIQISHSARETQQVVERASGHFES 353
Cdd:COG2770  409 LEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALE 488

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678 354 MIGDFESTNDKLADIAAHIQQFATTNTGINERVTRIYSDSQAIDQRMQHSATATRDLSGVAEKVQALLGRFVLGHGELDA 433
Cdd:COG2770  489 LLLLEEEEEAGAAAEELAEELLLLEGLLLLLLLEAEALEVAEELLELEEAALLLAAAAELAALLALLLALAAVEAAALLL 568

                        410       420       430
                 ....*....|....*....|....*....|....
gi 492088678 434 AITRASQCRDILQVRLAELHKQGVNLFDQSYKLI 467
Cdd:COG2770  569 AALLLAAVAALLELAALLLLLLAAAEALAALELE 602
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 98-143 1.81e-04

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 39.35  E-value: 1.81e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 492088678  98 VRPVMFMTHALEEIAngEGDLSRDLPLLTHDEIRVLASTCNRFLAK 143
Cdd:cd06225    1 TRPLRRLTEAARRIA--EGDLDVRVPVRSKDEIGELARAFNQMAER 44
HAMP pfam00672
HAMP domain;
93-146 2.10e-03

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 36.45  E-value: 2.10e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 492088678   93 FRHLIVRPVMFMTHALEEIAngEGDLSRDLPLLTHDEIRVLASTCNRFLAKQRE 146
Cdd:pfam00672   2 LARRILRPLRRLAEAARRIA--SGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
PRK11829 PRK11829
biofilm formation regulator HmsP; Provisional
 74-151 5.34e-03

biofilm formation regulator HmsP; Provisional


Pssm-ID: 183329 [Multi-domain]  Cd Length: 660  Bit Score: 39.93  E-value: 5.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492088678  74 AILLST--LFTLVMVSFMVWYFRHLIVRPVMFMTHALEEIANgEGDLSRDLPLLTH---DEIRVLASTCNR---FLAKQR 145
Cdd:PRK11829 147 SAMLSTylLLALVLSVSIAWCINRLIIHPLRAMAKELEDIGD-HGVLHHQLTLPAHhqdDELGVLVRNYNRnqqLLADAY 225


                 ....*.
gi 492088678 146 EVISSI 151
Cdd:PRK11829 226 ADMGRI 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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