NCBI Conserved Domain Search

Conserved domains on [gi|492172462|ref|WP_005770064|]

View

MULTISPECIES: Fe(3+) dicitrate ABC transporter ATP-binding protein FecE [Pseudomonas syringae group]

Protein Classification

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE( domain architecture ID 11485274)

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE is the ATPase subunit of the binding-protein-dependent transport system for citrate-dependent Fe(3+), and is responsible for energy coupling to the transport system

Graphical summary

Zoom to residue level

show extra options »

Show site features Horizontal zoom: ×

List of domain hits

Name

Accession

Description

Interval

E-value

fecE

PRK11231

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

2-256

1.90e-172

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 475.66 E-value: 1.90e-172

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAF 81
Cdd:PRK11231   1 MTLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQVLPIPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:PRK11231  81 LPQHHLTPEGITVRELVAYGRSPWLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQ 241
Cdd:PRK11231 161 LLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTPGLLRTVFDVEAE 240

                        250
                 ....*....|....*
gi 492172462 242 IMREPVAGTPMCIVE 256
Cdd:PRK11231 241 IHPEPVSGTPMCVVR 255

Name

Accession

Description

Interval

E-value

fecE

PRK11231

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

2-256

1.90e-172

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 475.66 E-value: 1.90e-172

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAF 81
Cdd:PRK11231   1 MTLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQVLPIPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:PRK11231  81 LPQHHLTPEGITVRELVAYGRSPWLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQ 241
Cdd:PRK11231 161 LLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTPGLLRTVFDVEAE 240

                        250
                 ....*....|....*
gi 492172462 242 IMREPVAGTPMCIVE 256
Cdd:PRK11231 241 IHPEPVSGTPMCVVR 255

FepC

COG1120

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...

3-254

4.02e-130

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];

Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 368.60 E-value: 4.02e-130

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFL 82
Cdd:COG1120    1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLPIPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:COG1120   81 PQEPPAPFGLTVRELVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQ 241
Cdd:COG1120  161 LDEPTSHLDLAHQLEVLELLRRLARErGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELLEEVYGVEAR 240

                        250
                 ....*....|...
gi 492172462 242 IMREPVAGTPMCI 254
Cdd:COG1120  241 VIEDPVTGRPLVL 253

ABC_Iron-Siderophores_B12_Hemin

cd03214

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...

5-221

6.05e-85

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.

Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 251.20 E-value: 6.05e-85

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   5 KAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPq 84
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVP- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 vlpipegvnvrqlvaygrsphnslwgrlsgadqhsvdQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLD 164
Cdd:cd03214   80 -------------------------------------QALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLD 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 165 EPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03214  123 EPTSHLDIAHQIELLELLRRLARErGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

12-212

4.61e-57

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 180.89 E-value: 4.61e-57

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLsldgkgysqlsARELACKVAFLPQVLPIPEG 91
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-----------RRAGGARVAYVPQRSEVPDS 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 --VNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTY 169
Cdd:NF040873  70 lpLTVRDLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 492172462 170 LDISHQVELLDLMRELSAEGKTVITVLHDINQAcRYADHLAVM 212
Cdd:NF040873 150 LDAESRERIIALLAEEHARGATVVVVTHDLELV-RRADPCVLL 191

anch_rpt_ABC

TIGR03771

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...

24-238

6.86e-41

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 140.37 E-value: 6.86e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   24 FSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlSARELACKVAFLPQV------LPIpegvNVRQL 97
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGA-----SPGKGWRHIGYVPQRhefawdFPI----SVAHT 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   98 VAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVE 177
Cdd:TIGR03771  72 VMSGRTGHIGWLRRPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQEL 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462  178 LLDLMRELSAEGKTVITVLHDINQACRYADHLaVMQGGRLVTCGAPGDVLTAELVCQVFDV 238
Cdd:TIGR03771 152 LTELFIELAGAGTAILMTTHDLAQAMATCDRV-VLLNGRVIADGTPQQLQDPAPWMTTFGV 211

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

19-168

4.96e-36

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 125.45 E-value: 4.96e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVNVRQLV 98
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462   99 AYGRsphnSLWGRLSGADQHSVDQALQRMELATLAERPLSD----LSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:pfam00005  81 RLGL----LLKGLSKREKDARAEEALEKLGLGDLADRPVGErpgtLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

13-228

3.31e-22

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 95.58 E-value: 3.31e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLK--AFARILtpQSGSLSLDGKGYSQLSARELAC-KVAFLPQVLpip 89
Cdd:NF033858  11 YGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSliAGARKI--QQGRVEVLGGDMADARHRRAVCpRIAYMPQGL--- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  90 eGVN------VRQLVAYgrsphnslWGRLSGADQHS----VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAA 159
Cdd:NF033858  86 -GKNlyptlsVFENLDF--------FGRLFGQDAAErrrrIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPD 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 160 IVLLDEPTTYLD-ISHQV--ELLDLMRElSAEGKTVITVLHDINQACRYaDHLAVMQGGRLVTCGAPGDVLT 228
Cdd:NF033858 157 LLILDEPTTGVDpLSRRQfwELIDRIRA-ERPGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAELLA 226

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

121-221

2.19e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 60.13 E-value: 2.19e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 121 DQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDIN 200
Cdd:NF000106 126 DELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYME 205

                         90       100
                 ....*....|....*....|.
gi 492172462 201 QACRYADHLAVMQGGRLVTCG 221
Cdd:NF000106 206 EAEQLAHELTVIDRGRVIADG 226

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

29-200

2.27e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 54.69 E-value: 2.27e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLdgkgysqlsarelackvaflpqvlpipegvnvrqlvaygrsphnsl 108
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIY---------------------------------------------- 35

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   109 wgrLSGADQHSVDQALQRMELATlaeRPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLD------LM 182
Cdd:smart00382  36 ---IDGEDILEEVLDQLLLIIVG---GKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLleelrlLL 109

                          170
                   ....*....|....*...
gi 492172462   183 RELSAEGKTVITVLHDIN 200
Cdd:smart00382 110 LLKSEKNLTVILTTNDEK 127

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

19-232

2.73e-09

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 57.44 E-value: 2.73e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysQLSARELAC--KVAFLPQVLPIPEGVNVRQ 96
Cdd:NF033858 282 VDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQ---PVDAGDIATrrRVGYMSQAFSLYGELTVRQ 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  97 -LVAYGRSPHnslwgrLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWL--AMILAQDaaIVLLDEPTTYLDI 172
Cdd:NF033858 359 nLELHARLFH------LPAAEIAArVAEMLERFDLADVADALPDSLPLGIRQRLSLavAVIHKPE--LLILDEPTSGVDP 430

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 173 SHQVELLDLMRELSAEGKTVITV-LHDINQACRyADHLAVMQGGRLVTCGAPgdvltAELV 232
Cdd:NF033858 431 VARDMFWRLLIELSREDGVTIFIsTHFMNEAER-CDRISLMHAGRVLASDTP-----AALV 485

GguA

NF040905

sugar ABC transporter ATP-binding protein;

20-218

1.64e-08

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 54.80 E-value: 1.64e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  20 QDLSFSPPAGQVTALIGPNGCGKSTLLKafarILT---PQ---SGSLSLDG-----KGYSQLSAR-------ELAckvaF 81
Cdd:NF040905  18 DDVNLSVREGEIHALCGENGAGKSTLMK----VLSgvyPHgsyEGEILFDGevcrfKDIRDSEALgiviihqELA----L 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQvLPIPEGV---NVRqlvaygrsphnSLWGRLSGADQHSvdQALQRMELATLAERP---LSDLSGGQRQRAWLAMILA 155
Cdd:NF040905  90 IPY-LSIAENIflgNER-----------AKRGVIDWNETNR--RARELLAKVGLDESPdtlVTDIGVGKQQLVEIAKALS 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462 156 QDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:NF040905 156 KDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVLRDGRTI 218

GguA

NF040905

sugar ABC transporter ATP-binding protein;

140-193

4.78e-04

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 40.93 E-value: 4.78e-04

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 492172462 140 LSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVI 193
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVI 458

Name

Accession

Description

Interval

E-value

fecE

PRK11231

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

2-256

1.90e-172

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 475.66 E-value: 1.90e-172

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAF 81
Cdd:PRK11231   1 MTLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQVLPIPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:PRK11231  81 LPQHHLTPEGITVRELVAYGRSPWLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQ 241
Cdd:PRK11231 161 LLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTPGLLRTVFDVEAE 240

                        250
                 ....*....|....*
gi 492172462 242 IMREPVAGTPMCIVE 256
Cdd:PRK11231 241 IHPEPVSGTPMCVVR 255

FepC

COG1120

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...

3-254

4.02e-130

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];

Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 368.60 E-value: 4.02e-130

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFL 82
Cdd:COG1120    1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLPIPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:COG1120   81 PQEPPAPFGLTVRELVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQ 241
Cdd:COG1120  161 LDEPTSHLDLAHQLEVLELLRRLARErGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELLEEVYGVEAR 240

                        250
                 ....*....|...
gi 492172462 242 IMREPVAGTPMCI 254
Cdd:COG1120  241 VIEDPVTGRPLVL 253

CeuD

COG4604

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...

13-254

1.10e-93

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 276.19 E-value: 1.10e-93

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGV 92
Cdd:COG4604   11 YGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKRLAILRQENHINSRL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQLVAYGRSPHNSlwGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDI 172
Cdd:COG4604   91 TVRELVAFGRFPYSK--GRLTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDM 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 173 SHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQImrEPVAGTP 251
Cdd:COG4604  169 KHSVQMMKLLRRLADElGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEIITPEVLSDIYDTDIEV--EEIDGKR 246


                 ...
gi 492172462 252 MCI 254
Cdd:COG4604  247 ICV 249

PRK10253

iron-enterobactin ABC transporter ATP-binding protein;

4-254

1.33e-88

iron-enterobactin ABC transporter ATP-binding protein;

Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 263.77 E-value: 1.33e-88

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLP 83
Cdd:PRK10253   8 LRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:PRK10253  88 QNATTPGDITVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 164 DEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQI 242
Cdd:PRK10253 168 DEPTTWLDISHQIDLLELLSELNREkGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIYGLRCMI 247

                        250
                 ....*....|..
gi 492172462 243 MREPVAGTPMCI 254
Cdd:PRK10253 248 IDDPVAGTPLVV 259

ABC_Iron-Siderophores_B12_Hemin

cd03214

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...

5-221

6.05e-85

Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 251.20 E-value: 6.05e-85

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   5 KAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPq 84
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVP- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 vlpipegvnvrqlvaygrsphnslwgrlsgadqhsvdQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLD 164
Cdd:cd03214   80 -------------------------------------QALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLD 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 165 EPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03214  123 EPTSHLDIAHQIELLELLRRLARErGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180

COG4559

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

4-252

3.59e-83

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 249.65 E-value: 3.59e-83

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLP 83
Cdd:COG4559    2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRRAVLP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVAYGRSPHnslwGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQ------- 156
Cdd:COG4559   82 QHSSLAFPFTVEEVVALGRAPH----GSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAQlwepvdg 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 157 DAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVF 236
Cdd:COG4559  158 GPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEVLTDELLERVY 237

                        250
                 ....*....|....*.
gi 492172462 237 DVHVQIMREPVAGTPM 252
Cdd:COG4559  238 GADLRVLAHPEGGCPQ 253

ZnuC

COG1121

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...

1-245

3.73e-82

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 246.54 E-value: 3.73e-82

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARelackVA 80
Cdd:COG1121    4 MPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRR-----IG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQVLPIPEG--VNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDA 158
Cdd:COG1121   79 YVPQRAEVDWDfpITVRDVVLMGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDP 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 159 AIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMqGGRLVTCGAPGDVLTAELVCQVFDV 238
Cdd:COG1121  159 DLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLL-NRGLVAHGPPEEVLTPENLSRAYGG 237


                 ....*..
gi 492172462 239 HVQIMRE 245
Cdd:COG1121  238 PVALLAH 244

hmuV

PRK13548

hemin importer ATP-binding subunit; Provisional

4-252

1.45e-77

hemin importer ATP-binding subunit; Provisional

Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 235.44 E-value: 1.45e-77

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLP 83
Cdd:PRK13548   3 LEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAVLP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVAYGRSPhnslWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAA---- 159
Cdd:PRK13548  83 QHSSLSFPFTVEEVVAMGRAP----HGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAQLWEpdgp 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 160 --IVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVF 236
Cdd:PRK13548 159 prWLLLDEPTSALDLAHQHHVLRLARQLAHErGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVLTPETLRRVY 238

                        250
                 ....*....|....*.
gi 492172462 237 DVHVQIMREPVAGTPM 252
Cdd:PRK13548 239 GADVLVQPHPETGAPL 254

PRK10575

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

18-255

2.54e-76

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 232.37 E-value: 2.54e-76

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVNVRQL 97
Cdd:PRK10575  26 LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPAAEGMTVREL 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  98 VAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVE 177
Cdd:PRK10575 106 VAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVD 185

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 178 LLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQIMREPVAGTPMCIV 255
Cdd:PRK10575 186 VLALVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGETLEQIYGIPMGILPHPAGAAPVSFV 264

btuD

PRK09536

corrinoid ABC transporter ATPase; Reviewed

1-251

5.50e-70

corrinoid ABC transporter ATPase; Reviewed

Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 220.87 E-value: 5.50e-70

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVA 80
Cdd:PRK09536   1 MPMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQVLPIPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAI 160
Cdd:PRK09536  81 SVPQDTSLSFEFDVRQVVEMGRTPHRSRFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 161 VLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHV 240
Cdd:PRK09536 161 LLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADTLRAAFDART 240

                        250
                 ....*....|.
gi 492172462 241 QIMREPVAGTP 251
Cdd:PRK09536 241 AVGTDPATGAP 251

ABC_Metallic_Cations

cd03235

ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...

5-212

1.27e-68

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.

Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 210.85 E-value: 1.27e-68

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   5 KAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARelackVAFLPQ 84
Cdd:cd03235    1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKR-----IGYVPQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 VLPIPEG--VNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:cd03235   76 RRSIDRDfpISVRDVVLMGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLL 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVM 212
Cdd:cd03235  156 LDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLL 205

EcfA2

COG1122

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...

4-230

4.88e-60

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];

Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 189.47 E-value: 4.88e-60

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGY-GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFL 82
Cdd:COG1122    1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRKVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQ------VLPIpegvnVRQLVAYGrsPHNSlwgRLSGAD-QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILA 155
Cdd:COG1122   81 FQnpddqlFAPT-----VEEDVAFG--PENL---GLPREEiRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLA 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 156 QDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:COG1122  151 MEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDY 225

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

12-212

4.61e-57

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 180.89 E-value: 4.61e-57

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLsldgkgysqlsARELACKVAFLPQVLPIPEG 91
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-----------RRAGGARVAYVPQRSEVPDS 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 --VNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTY 169
Cdd:NF040873  70 lpLTVRDLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 492172462 170 LDISHQVELLDLMRELSAEGKTVITVLHDINQAcRYADHLAVM 212
Cdd:NF040873 150 LDAESRERIIALLAEEHARGATVVVVTHDLELV-RRADPCVLL 191

CcmA

COG1131

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

4-231

1.54e-56

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 181.03 E-value: 1.54e-56

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAcKVAFLP 83
Cdd:COG1131    1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRR-RIGYVP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVAYgrsphnslWGRLSGADQHS----VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAA 159
Cdd:COG1131   80 QEPALYPDLTVRENLRF--------FARLYGLPRKEarerIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPE 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 160 IVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAEL 231
Cdd:COG1131  152 LLILDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARLL 223

NatA

COG4555

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...

4-227

5.84e-55

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];

Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 176.97 E-value: 5.84e-55

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAcKVAFLP 83
Cdd:COG4555    2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARR-QIGVLP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVAYgrspHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:COG4555   81 DERGLYDRLTVRENIRY----FAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLL 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 164 DEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:COG4555  157 DEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELR 220

ABC_cobalt_CbiO_domain1

cd03225

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...

14-216

4.60e-54

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 173.81 E-value: 4.60e-54

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVlpiPE--- 90
Cdd:cd03225   12 GARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLVFQN---PDdqf 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 -GVNVRQLVAYGrsPHNSLwgrLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:cd03225   89 fGPTVEEEVAFG--LENLG---LPEEEIEErVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTA 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 492172462 169 YLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGR 216
Cdd:cd03225  164 GLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211

hmuV

PRK13547

heme ABC transporter ATP-binding protein;

3-255

6.71e-54

heme ABC transporter ATP-binding protein;

Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 175.40 E-value: 6.71e-54

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQ--------SGSLSLDGKGYSQLSARE 74
Cdd:PRK13547   1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAAIDAPR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  75 LACKVAFLPQVLPIPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMIL 154
Cdd:PRK13547  81 LARLRAVLPQAAQPAFAFSAREIVLLGRYPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 155 AQ---------DAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKT-VITVLHDINQACRYADHLAVMQGGRLVTCGAPG 224
Cdd:PRK13547 161 AQlwpphdaaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLgVLAIVHDPNLAARHADRIAMLADGAIVAHGAPA 240

                        250       260       270
                 ....*....|....*....|....*....|.
gi 492172462 225 DVLTAELVCQVFDVHVQIMREPvAGTPMCIV 255
Cdd:PRK13547 241 DVLTPAHIARCYGFAVRLVDAG-DGVPPVIV 270

BtuD

COG4138

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...

19-256

2.45e-53

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];

Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 173.10 E-value: 2.45e-53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARiLTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVNVRQLV 98
Cdd:COG4138   12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAG-LLPGQGEILLNGRPLSDWSAAELARHRAYLSQQQSPPFAMPVFQYL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  99 AYGRSPHNSlwgrlSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQ-------DAAIVLLDEPTTYLD 171
Cdd:COG4138   91 ALHQPAGAS-----SEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwptinpEGQLLLLDEPMNSLD 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 172 ISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQIMRepVAGTP 251
Cdd:COG4138  166 VAQQAALDRLLRELCQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTPENLSEVFGVKFRRLE--VEGHR 243


                 ....*
gi 492172462 252 MCIVE 256
Cdd:COG4138  244 WLIPT 248

PhnC

COG3638

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...

2-231

4.09e-53

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 172.55 E-value: 4.09e-53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGY-GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELA---C 77
Cdd:COG3638    1 PMLELRNLSKRYpGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRrlrR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 KVAFLPQVLPIPEGVNVRQLVAYGRSPHNSLW----GRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMI 153
Cdd:COG3638   81 RIGMIFQQFNLVPRLSVLTNVLAGRLGRTSTWrsllGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAIARA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 154 LAQDAAIVLLDEPTTYLD--ISHQVelLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:COG3638  161 LVQEPKLILADEPVASLDpkTARQV--MDLLRRIAREdGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAELTDAV 238


                 .
gi 492172462 231 L 231
Cdd:COG3638  239 L 239

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

3-229

4.27e-50

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 171.62 E-value: 4.27e-50

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGY-----GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAc 77
Cdd:COG1123  260 LLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLR- 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 kvAFLPQVLPI---PEG-----VNVRQLVAYGRSPHnslwGRLSGADQHS-VDQALQRMEL-ATLAERPLSDLSGGQRQR 147
Cdd:COG1123  339 --ELRRRVQMVfqdPYSslnprMTVGDIIAEPLRLH----GLLSRAERRErVAELLERVGLpPDLADRYPHELSGGQRQR 412

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 148 AWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:COG1123  413 VAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRElGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEV 492


                 ...
gi 492172462 227 LTA 229
Cdd:COG1123  493 FAN 495

ABC_Carb_Solutes_like

cd03259

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...

4-221

1.26e-46

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 154.60 E-value: 1.26e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELacKVAFLP 83
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERR--NIGMVF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVAYGrsphnsLWGRLSGADQH--SVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:cd03259   79 QDYALFPHLTVAENIAFG------LKLRGVPKAEIraRVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLL 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03259  153 LLDEPLSALDAKLREELREELKELQRElGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

3-221

1.32e-46

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 154.97 E-value: 1.32e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGY----GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC- 77
Cdd:cd03257    1 LLEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKIr 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 --KVAFLPQvlpipegvnvrqlvaygrSPHNSLWGRLSGADQ----------HSVDQALQRMELATLAERPLSD------ 139
Cdd:cd03257   81 rkEIQMVFQ------------------DPMSSLNPRMTIGEQiaeplrihgkLSKKEARKEAVLLLLVGVGLPEevlnry 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 140 ---LSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGG 215
Cdd:cd03257  143 pheLSGGQRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDLGVVAKIADRVAVMYAG 222


                 ....*.
gi 492172462 216 RLVTCG 221
Cdd:cd03257  223 KIVEEG 228

ABC_DR_subfamily_A

cd03230

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...

4-217

2.62e-46

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 152.55 E-value: 2.62e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQlSARELACKVAFLP 83
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKK-EPEEVKRRIGYLP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVaygrsphnslwgrlsgadqhsvdqalqrmelatlaerplsDLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:cd03230   80 EEPSLYENLTVRENL----------------------------------------KLSGGMKQRLALAQALLHDPELLIL 119

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 492172462 164 DEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:cd03230  120 DEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

1-229

2.81e-45

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 158.91 E-value: 2.81e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MS-ILKAQHLDIGY--GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQ---SGSLSLDGKGYSQLSARE 74
Cdd:COG1123    1 MTpLLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  75 LACKVAFLPQVlpiPE----GVNVRQLVAYGrsphnSLWGRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAW 149
Cdd:COG1123   81 RGRRIGMVFQD---PMtqlnPVTVGDQIAEA-----LENLGLSRAEARArVLELLEAVGLERRLDRYPHQLSGGQRQRVA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 150 LAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:COG1123  153 IAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILA 232


                 .
gi 492172462 229 A 229
Cdd:COG1123  233 A 233

ABC_ATPase

cd00267

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...

5-216

4.80e-45

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 148.93 E-value: 4.80e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   5 KAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQ 84
Cdd:cd00267    1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 vlpipegvnvrqlvaygrsphnslwgrlsgadqhsvdqalqrmelatlaerplsdLSGGQRQRAWLAMILAQDAAIVLLD 164
Cdd:cd00267   81 -------------------------------------------------------LSGGQRQRVALARALLLNPDLLLLD 105

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 492172462 165 EPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGR 216
Cdd:cd00267  106 EPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157

ABC_Mj1267_LivG_branched

cd03219

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...

4-232

7.93e-45

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).

Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 150.67 E-value: 7.93e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELA-CKVA-- 80
Cdd:cd03219    1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIArLGIGrt 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 F-LPQVLP---IPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQ 156
Cdd:cd03219   81 FqIPRLFPeltVLENVMVAAQARTGSGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALAT 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 157 DAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELV 232
Cdd:cd03219  161 DPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPRV 236

ABC_PhnC_transporter

cd03256

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...

4-236

1.27e-44

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 150.41 E-value: 1.27e-44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGA-TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC---KV 79
Cdd:cd03256    1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQlrrQI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQVLPIPEGVNVRQLVAYGR----SPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILA 155
Cdd:cd03256   81 GMIFQQFNLIERLSVLENVLSGRlgrrSTWRSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 156 QDAAIVLLDEPTTYLD--ISHQVelLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDvLTAELV 232
Cdd:cd03256  161 QQPKLILADEPVASLDpaSSRQV--MDLLKRINREeGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAE-LTDEVL 237


                 ....
gi 492172462 233 CQVF 236
Cdd:cd03256  238 DEIY 241

ABC_cobalt_CbiO_domain2

cd03226

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...

6-218

1.55e-43

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 146.63 E-value: 1.55e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   6 AQHLDIGYG-ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysQLSARELACKVAFLPQ 84
Cdd:cd03226    2 IENISFSYKkGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGK---PIKAKERRKSIGYVMQ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 vlpipegvNV-RQLvaYGRSPHNSLwgRLS----GADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAA 159
Cdd:cd03226   79 --------DVdYQL--FTDSVREEL--LLGlkelDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKD 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 160 IVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:cd03226  147 LLIFDEPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205

DppF

COG1124

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

4-218

3.75e-43

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 146.87 E-value: 3.75e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGA----TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKV 79
Cdd:COG1124    2 LEVRNLSVSYGQggrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRRRV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQVlpiPEG-VNVRQLVayGRSPHNSLWGRLSGADQHSVDQALQRMEL-ATLAERPLSDLSGGQRQRAWLAMILAQD 157
Cdd:COG1124   82 QMVFQD---PYAsLHPRHTV--DRILAEPLRIHGLPDREERIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARALILE 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 158 AAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:COG1124  157 PELLLLDEPTSALDVSVQAEILNLLKDLREErGLTYLFVSHDLAVVAHLCDRVAVMQNGRIV 218

FetA

COG4619

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

4-217

5.53e-43

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 145.34 E-value: 5.53e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLP 83
Cdd:COG4619    1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEWRRQVAYVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGvNVRQLVAYGRSPHNSLWgrlsgaDQHSVDQALQRMEL-ATLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:COG4619   81 QEPALWGG-TVRDNLPFPFQLRERKF------DRERALELLERLGLpPDILDKPVERLSGGERQRLALIRALLLQPDVLL 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:COG4619  154 LDEPTSALDPENTRRVEELLREYLAEeGRAVLWVSHDPEQIERVADRVLTLEAGRL 209

CcmA

COG4133

ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...

4-198

8.87e-43

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 144.54 E-value: 8.87e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGySQLSARELACKVAFLP 83
Cdd:COG4133    3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEP-IRDAREDYRRRLAYLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVAygrsphnsLWGRLSG--ADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:COG4133   82 HADGLKPELTVRENLR--------FWAALYGlrADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLW 153

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHD 198
Cdd:COG4133  154 LLDEPFTALDAAGVALLAELIAAHLARGGAVLLTTHQ 190

CysA

COG1118

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...

1-227

2.43e-42

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 147.60 E-value: 2.43e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSIlKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKG-YSQLSARELacKV 79
Cdd:COG1118    1 MSI-EVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDlFTNLPPRER--RV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQvlpipegvN--------VRQLVAYG---RSPhnslwgrlSGAD-QHSVDQALQRMELATLAERPLSDLSGGQRQR 147
Cdd:COG1118   78 GFVFQ--------HyalfphmtVAENIAFGlrvRPP--------SKAEiRARVEELLELVQLEGLADRYPSQLSGGQRQR 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 148 AWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMREL-SAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:COG1118  142 VALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLhDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEV 221


                 .
gi 492172462 227 L 227
Cdd:COG1118  222 Y 222

PRK03695

vitamin B12-transporter ATPase; Provisional

22-255

3.67e-42

vitamin B12-transporter ATPase; Provisional

Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 144.31 E-value: 3.67e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  22 LSFSPPAGQVTALIGPNGCGKSTLLKAFARiLTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVNVRQLVAYG 101
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAG-LLPGSGSIQFAGQPLEAWSAAELARHRAYLSQQQTPPFAMPVFQYLTLH 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 102 RSPHNSLwgrlsGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQ-------DAAIVLLDEPTTYLDISH 174
Cdd:PRK03695  94 QPDKTRT-----EAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQvwpdinpAGQLLLLDEPMNSLDVAQ 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 175 QVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVHVQimREPVAGTPMCI 254
Cdd:PRK03695 169 QAALDRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPENLAQVFGVNFR--RLDVEGHPMLI 246


                 .
gi 492172462 255 V 255
Cdd:PRK03695 247 S 247

PotA

COG3842

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...

1-226

3.60e-41

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 144.47 E-value: 3.60e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelacKVA 80
Cdd:COG3842    3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGR------------DVT 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPqvlpiPE--GVN-------------VRQLVAYG---RsphnslwgRLSGADQHS-VDQALQRMELATLAERPLSDLS 141
Cdd:COG3842   71 GLP-----PEkrNVGmvfqdyalfphltVAENVAFGlrmR--------GVPKAEIRArVAELLELVGLEGLADRYPHQLS 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 142 GGQRQRAWLAMILAQDAAIVLLDEPTTYLD----ISHQVELLDLMRELsaeGKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:COG3842  138 GGQQQRVALARALAPEPRVLLLDEPLSALDaklrEEMREELRRLQREL---GITFIYVTHDQEEALALADRIAVMNDGRI 214


                 ....*....
gi 492172462 218 VTCGAPGDV 226
Cdd:COG3842  215 EQVGTPEEI 223

LivG

COG0411

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...

1-232

4.41e-41

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];

Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 141.71 E-value: 4.41e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELA-CKV 79
Cdd:COG0411    2 DPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIArLGI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 A--FlpQVLPIPEGVNVRQ--LVAYGRSPHNSLWGRLSG---------ADQHSVDQALQRMELATLAERPLSDLSGGQRQ 146
Cdd:COG0411   82 ArtF--QNPRLFPELTVLEnvLVAAHARLGRGLLAALLRlprarreerEARERAEELLERVGLADRADEPAGNLSYGQQR 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 147 RAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGD 225
Cdd:COG0411  160 RLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDErGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAE 239


                 ....*..
gi 492172462 226 VLTAELV 232
Cdd:COG0411  240 VRADPRV 246

ABC_PstB_phosphate_transporter

cd03260

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...

4-218

5.64e-41

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).

Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 140.78 E-value: 5.64e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARIL-----TPQSGSLSLDGKGYSQLSAR--ELA 76
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLLDGKDIYDLDVDvlELR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  77 CKVAFLPQvLPIPEGVNVRQLVAYGRSPHNSLWGRLSGAdqhSVDQALQRMELATLAERPLS--DLSGGQRQRAWLAMIL 154
Cdd:cd03260   81 RRVGMVFQ-KPNPFPGSIYDNVAYGLRLHGIKLKEELDE---RVEEALRKAALWDEVKDRLHalGLSGGQQQRLCLARAL 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 155 AQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEgKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:cd03260  157 ANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGRLV 219

anch_rpt_ABC

TIGR03771

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...

24-238

6.86e-41

Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 140.37 E-value: 6.86e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   24 FSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlSARELACKVAFLPQV------LPIpegvNVRQL 97
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGA-----SPGKGWRHIGYVPQRhefawdFPI----SVAHT 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   98 VAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVE 177
Cdd:TIGR03771  72 VMSGRTGHIGWLRRPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQEL 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462  178 LLDLMRELSAEGKTVITVLHDINQACRYADHLaVMQGGRLVTCGAPGDVLTAELVCQVFDV 238
Cdd:TIGR03771 152 LTELFIELAGAGTAILMTTHDLAQAMATCDRV-VLLNGRVIADGTPQQLQDPAPWMTTFGV 211

ModF

COG1119

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...

1-245

1.14e-40

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];

Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 140.60 E-value: 1.14e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSG-SLSLDGKGYSQLSARELACKV 79
Cdd:COG1119    1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGGEDVWELRKRI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQVL--PIPEGVNVRQLVAYGRspHNS--LWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILA 155
Cdd:COG1119   81 GLVSPALqlRFPRDETVLDVVLSGF--FDSigLYREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALV 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 156 QDAAIVLLDEPTTYLDISHQVELLDLMRELSAEG-KTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQ 234
Cdd:COG1119  159 KDPELLILDEPTAGLDLGARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVLTSENLSE 238

                        250
                 ....*....|.
gi 492172462 235 VFDVHVQIMRE 245
Cdd:COG1119  239 AFGLPVEVERR 249

MlaF

COG1127

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...

3-230

2.33e-40

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 139.34 E-value: 2.33e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELA---CKV 79
Cdd:COG1127    5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYelrRRI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQvlpipEG-----VNVRQLVAYgrsP---HnslwGRLSGAD-QHSVDQALQRMELATLAERPLSDLSGGQRQRAWL 150
Cdd:COG1127   85 GMLFQ-----GGalfdsLTVFENVAF---PlreH----TDLSEAEiRELVLEKLELVGLPGAADKMPSELSGGMRKRVAL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 151 AMILAQDAAIVLLDEPTTYLD-ISHQVeLLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:COG1127  153 ARALALDPEILLYDEPTAGLDpITSAV-IDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLA 231


                 ..
gi 492172462 229 AE 230
Cdd:COG1127  232 SD 233

ABC_OpuCA_Osmoprotection

cd03295

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...

14-228

5.64e-40

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 138.59 E-value: 5.64e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLpipegvn 93
Cdd:cd03295   12 GGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRRKIGYVIQQI------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 vrqlvayGRSPHNSLWG------RLSGADQHSVDQ------ALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:cd03295   85 -------GLFPHMTVEEnialvpKLLKWPKEKIREradellALVGLDPAEFADRYPHELSGGQQQRVGVARALAADPPLL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 162 LLDEPTTYLD----ISHQVELLDLMRELsaeGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:cd03295  158 LMDEPFGALDpitrDQLQEEFKRLQQEL---GKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILR 225

ThiQ

COG3840

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

23-230

1.18e-39

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 137.19 E-value: 1.18e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  23 SFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQL--SARelacKVAFLPQvlpipEG-----VNVR 95
Cdd:COG3840   19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALppAER----PVSMLFQ-----ENnlfphLTVA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  96 QLVAYGRSPHnslwGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQ 175
Cdd:COG3840   90 QNIGLGLRPG----LKLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPALR 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 176 VELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:COG3840  166 QEMLDLVDELCRErGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGE 221

CydD

COG4988

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...

4-227

1.44e-39

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 144.13 E-value: 1.44e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGY-GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFL 82
Cdd:COG4988  337 IELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRRQIAWV 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLPIPEGvNVRQLVAYGRsphnslwgrlSGADQHSVDQALQRMELATLAER-------PLSD----LSGGQRQRAWLA 151
Cdd:COG4988  417 PQNPYLFAG-TIRENLRLGR----------PDASDEELEAALEAAGLDEFVAAlpdgldtPLGEggrgLSGGQAQRLALA 485

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 152 MILAQDAAIVLLDEPTTYLDISHQVELLDLMRELsAEGKTVITVLHDINQAcRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:COG4988  486 RALLRDAPLLLLDEPTAHLDAETEAEILQALRRL-AKGRTVILITHRLALL-AQADRILVLDDGRIVEQGTHEELL 559

LolD

COG1136

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

2-218

1.32e-38

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 134.40 E-value: 1.32e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHL----DIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELA- 76
Cdd:COG1136    3 PLLELRNLtksyGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELAr 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  77 ---CKVAFLPQ---VLPipeGVNVRQLVAYgrsPHnSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWL 150
Cdd:COG1136   83 lrrRHIGFVFQffnLLP---ELTALENVAL---PL-LLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAI 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 151 AMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQAcRYADHLAVMQGGRLV 218
Cdd:COG1136  156 ARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPELA-ARADRVIRLRDGRIV 223

ABC_phnC

TIGR02315

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...

3-223

2.37e-38

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]

Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 134.35 E-value: 2.37e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    3 ILKAQHLDIGYG-ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSAREL---ACK 78
Cdd:TIGR02315   1 MLEVENLSKVYPnGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLrklRRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   79 VAFLPQVLPIPEGVNVRQLVAYGR----SPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMIL 154
Cdd:TIGR02315  81 IGMIFQHYNLIERLTVLENVLHGRlgykPTWRSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARAL 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462  155 AQDAAIVLLDEPTTYLD--ISHQVelLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAP 223
Cdd:TIGR02315 161 AQQPDLILADEPIASLDpkTSKQV--MDYLKRINKEdGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAP 230

ABC_MJ0796_LolCDE_FtsE

cd03255

ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...

4-217

3.32e-38

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.

Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 133.00 E-value: 3.32e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGA----TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC-- 77
Cdd:cd03255    1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAfr 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 --KVAFLPQ---VLPipeGVNVRQLVAYGrsphnSLWGRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLA 151
Cdd:cd03255   81 rrHIGFVFQsfnLLP---DLTALENVELP-----LLLAGVPKKERRErAEELLERVGLGDRLNHYPSELSGGQQQRVAIA 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 152 MILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQAcRYADHLAVMQGGRL 217
Cdd:cd03255  153 RALANDPKIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDPELA-EYADRIIELRDGKI 218

ABC_Org_Solvent_Resistant

cd03261

ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...

7-228

6.71e-38

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 133.01 E-value: 6.71e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   7 QHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSAREL---ACKVAFLP 83
Cdd:cd03261    4 RGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELyrlRRRMGMLF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVAYGRSPHnslwGRLSgaDQHSVDQALQRMELATLAE----RPlSDLSGGQRQRAWLAMILAQDAA 159
Cdd:cd03261   84 QSGALFDSLTVFENVAFPLREH----TRLS--EEEIREIVLEKLEAVGLRGaedlYP-AELSGGMKKRVALARALALDPE 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 160 IVLLDEPTTYLD-ISHQVeLLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:cd03261  157 LLLYDEPTAGLDpIASGV-IDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226

ABC_putative_ATPase

cd03269

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...

4-221

5.00e-37

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 130.09 E-value: 5.00e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYsQLSARElacKVAFLP 83
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPL-DIAARN---RIGYLP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVR-QLVAYGRsphnsLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:cd03269   77 EERGLYPKMKVIdQLVYLAQ-----LKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLI 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03269  152 LDEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210

cbiO

TIGR01166

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...

14-202

1.40e-36

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 128.31 E-value: 1.40e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK--GYSQLSARELACKVAFlpqVLPIPE- 90
Cdd:TIGR01166   3 GGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEplDYSRKGLLERRQRVGL---VFQDPDd 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   91 ---GVNVRQLVAYGrsPHNSlwgRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:TIGR01166  80 qlfAADVDQDVAFG--PLNL---GLSEAEVERrVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEP 154

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 492172462  167 TTYLDISHQVELLDLMRELSAEGKTVITVLHDINQA 202
Cdd:TIGR01166 155 TAGLDPAGREQMLAILRRLRAEGMTVVISTHDVDLA 190

ABCC_MRP_Like

cd03228

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...

4-216

1.55e-36

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 127.50 E-value: 1.55e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGAT--RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAF 81
Cdd:cd03228    1 IEFKNVSFSYPGRpkPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKNIAY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQvlpipegvnvrqlvaygrSPHnslwgRLSGadqhsvdqalqrmelaTLAErplSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:cd03228   81 VPQ------------------DPF-----LFSG----------------TIRE---NILSGGQRQRIAIARALLRDPPIL 118

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELSaEGKTVITVLHDINQAcRYADHLAVMQGGR 216
Cdd:cd03228  119 ILDEATSALDPETEALILEALRALA-KGKTVIVIAHRLSTI-RDADRIIVLDDGR 171

ABC_Class3

cd03229

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...

4-216

3.20e-36

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 126.92 E-value: 3.20e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSA--RELACKVAF 81
Cdd:cd03229    1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDelPPLRRRIGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQVLPIPEGVNVRQLVAYGrsphnslwgrlsgadqhsvdqalqrmelatlaerplsdLSGGQRQRAWLAMILAQDAAIV 161
Cdd:cd03229   81 VFQDFALFPHLTVLENIALG--------------------------------------LSGGQQQRVALARALAMDPDVL 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGR 216
Cdd:cd03229  123 LLDEPTSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178

ABC_drug_resistance_like

cd03264

ABC-type multidrug transport system, ATPase component; The biological function of this family ...

4-221

3.30e-36

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 127.69 E-value: 3.30e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGqVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGkgYSQLSAR-ELACKVAFL 82
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDG--QDVLKQPqKLRRRIGYL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLPIPEGVNVRQLVAYgrsphNSLWGRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:cd03264   78 PQEFGVYPNFTVREFLDY-----IAWLKGIPSKEVKArVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSIL 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELSAEgKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03264  153 IVDEPTAGLDPEERIRFRNLLSELGED-RIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211

YhaQ

COG4152

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

3-221

4.82e-36

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 129.84 E-value: 4.82e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARelacKVAFL 82
Cdd:COG4152    1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEDRR----RIGYL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 pqvlpiPE--G----VNVR-QLVAYGRsphnsLWGrLSGAD-QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMIL 154
Cdd:COG4152   77 ------PEerGlypkMKVGeQLVYLAR-----LKG-LSKAEaKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAAL 144

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 155 AQDAAIVLLDEPTTYLD-IShqVELL-DLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:COG4152  145 LHDPELLILDEPFSGLDpVN--VELLkDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSG 211

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

19-168

4.96e-36

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 125.45 E-value: 4.96e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVNVRQLV 98
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462   99 AYGRsphnSLWGRLSGADQHSVDQALQRMELATLAERPLSD----LSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:pfam00005  81 RLGL----LLKGLSKREKDARAEEALEKLGLGDLADRPVGErpgtLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

LivF

COG0410

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...

1-232

8.46e-36

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];

Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 127.41 E-value: 8.46e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACK-V 79
Cdd:COG0410    1 MPMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLgI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQ---VLPipeGVNVR---QLVAYGRSphnslwgrlsgaDQHSVDQALQRM-----ELATLAERPLSDLSGGQRQRA 148
Cdd:COG0410   81 GYVPEgrrIFP---SLTVEenlLLGAYARR------------DRAEVRADLERVyelfpRLKERRRQRAGTLSGGEQQML 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 149 WLAMILAQDAAIVLLDEPTtyLDISHQV--ELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:COG0410  146 AIGRALMSRPKLLLLDEPS--LGLAPLIveEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAEL 223


                 ....*.
gi 492172462 227 LTAELV 232
Cdd:COG0410  224 LADPEV 229

ABC_TM1139_LivF_branched

cd03224

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...

4-227

8.51e-36

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.

Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 127.17 E-value: 8.51e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACK-VAFL 82
Cdd:cd03224    1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAgIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLPIPEGVNVR---QLVAYGRSPhnslwgrlsGADQHSVDQALQRM-ELATLAERPLSDLSGGQRQRAWLAMILAQDA 158
Cdd:cd03224   81 PEGRRIFPELTVEenlLLGAYARRR---------AKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRP 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 159 AIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:cd03224  152 KLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELL 220

ABC_NrtD_SsuB_transporters

cd03293

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...

4-218

1.91e-35

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 126.05 E-value: 1.91e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYG----ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlSARELACKV 79
Cdd:cd03293    1 LEVRNVSKTYGggggAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGE-----PVTGPGPDR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQ---VLPipeGVNVRQLVAYGRsphnSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQ 156
Cdd:cd03293   76 GYVFQqdaLLP---WLTVLDNVALGL----ELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAV 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 157 DAAIVLLDEPTTYLD----ISHQVELLDLMRElsaEGKTVITVLHDINQACRYADHLAVMQG--GRLV 218
Cdd:cd03293  149 DPDVLLLDEPFSALDaltrEQLQEELLDIWRE---TGKTVLLVTHDIDEAVFLADRVVVLSArpGRIV 213

ABC_CysA_sulfate_importer

cd03296

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...

1-226

2.48e-35

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 126.30 E-value: 2.48e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSIlKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELacKVA 80
Cdd:cd03296    1 MSI-EVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQER--NVG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQVLPIPEGVNVRQLVAYG-RSPHNSlwGRLSGAD-QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDA 158
Cdd:cd03296   78 FVFQHYALFRHMTVFDNVAFGlRVKPRS--ERPPEAEiRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEP 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 159 AIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:cd03296  156 KVLLLDEPFGALDAKVRKELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEV 224

PRK15056

manganese/iron ABC transporter ATP-binding protein;

19-236

3.76e-35

manganese/iron ABC transporter ATP-binding protein;

Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 126.92 E-value: 3.76e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELackVAFLPQVLPIPEG--VNVRQ 96
Cdd:PRK15056  23 LRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNL---VAYVPQSEEVDWSfpVLVED 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  97 LVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQV 176
Cdd:PRK15056 100 VVMMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEA 179

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 177 ELLDLMRELSAEGKTVITVLHDINQACRYADHlAVMQGGRLVTCGAPGDVLTAELVCQVF 236
Cdd:PRK15056 180 RIISLLRELRDEGKTMLVSTHNLGSVTEFCDY-TVMVKGTVLASGPTETTFTAENLELAF 238

PstB

COG1117

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...

2-221

4.50e-35

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 126.30 E-value: 4.50e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARI--LTPQ---SGSLSLDGKG-YS-QLSARE 74
Cdd:COG1117   10 PKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMndLIPGarvEGEILLDGEDiYDpDVDVVE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  75 LACKVAFLPQVL-PIPEGV--NvrqlVAYG-RsphnsLWGRLSGAD-QHSVDQALQRMEL-----ATLAERPLSdLSGGQ 144
Cdd:COG1117   90 LRRRVGMVFQKPnPFPKSIydN----VAYGlR-----LHGIKSKSElDEIVEESLRKAALwdevkDRLKKSALG-LSGGQ 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 145 RQRAWLAMILAQDAAIVLLDEPTTYLD-IS-HQVEllDLMRELSAEgKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:COG1117  160 QQRLCIARALAVEPEVLLMDEPTSALDpIStAKIE--ELILELKKD-YTIVIVTHNMQQAARVSDYTAFFYLGELVEFG 235

ABC_ThiQ_thiamine_transporter

cd03298

ATP-binding cassette domain of the thiamine transport system; Part of the ...

13-221

4.80e-35

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 124.91 E-value: 4.80e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFspPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQL--SARelacKVAFLPQVLPIPE 90
Cdd:cd03298   10 YGEQPMHFDLTF--AQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAppADR----PVSMLFQENNLFA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 GVNVRQLVAYGRSPhnSLwgRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYL 170
Cdd:cd03298   84 HLTVEQNVGLGLSP--GL--KLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAAL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 492172462 171 DISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03298  160 DPALRAEMLDLVLDLHAEtKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211

ECF_ATPase_2

TIGR04521

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...

21-228

6.83e-35

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 126.03 E-value: 6.83e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   21 DLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK---GYSQLSARELACKVAFLPQvlpIPEgvnvRQL 97
Cdd:TIGR04521  23 DVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRditAKKKKKLKDLRKKVGLVFQ---FPE----HQL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   98 --------VAYGrsPHNslWGrLSGADQHS-VDQALQRMEL-ATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPT 167
Cdd:TIGR04521  96 feetvykdIAFG--PKN--LG-LSEEEAEErVKEALELVGLdEEYLERSPFELSGGQMRRVAIAGVLAMEPEVLILDEPT 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462  168 TYLDISHQVELLDLMREL-SAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:TIGR04521 171 AGLDPKGRKEILDLFKRLhKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFS 232

CydC

COG4987

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...

4-227

7.39e-35

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 131.43 E-value: 7.39e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGY-GATRIV-QDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAF 81
Cdd:COG4987  334 LELEDVSFRYpGAGRPVlDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRRIAV 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQVLPIPEGvNVRQ--LVAYGRSPHNSLWgrlsgadqhsvdQALQRMELATLAERpLSD------------LSGGQRQR 147
Cdd:COG4987  414 VPQRPHLFDT-TLREnlRLARPDATDEELW------------AALERVGLGDWLAA-LPDgldtwlgeggrrLSGGERRR 479

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 148 AWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELsAEGKTVITVLHDInQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:COG4987  480 LALARALLRDAPILLLDEPTEGLDAATEQALLADLLEA-LAGRTVLLITHRL-AGLERMDRILVLEDGRIVEQGTHEELL 557

cbiO

PRK13635

energy-coupling factor ABC transporter ATP-binding protein;

2-226

8.58e-35

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 125.90 E-value: 8.58e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGY--GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKV 79
Cdd:PRK13635   4 EIIRVEHISFRYpdAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRRQV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFlpqVLPIPE----GVNVRQLVAYGRS----PHNSLWGRlsgadqhsVDQALQRMELATLAERPLSDLSGGQRQRAWLA 151
Cdd:PRK13635  84 GM---VFQNPDnqfvGATVQDDVAFGLEnigvPREEMVER--------VDQALRQVGMEDFLNREPHRLSGGQKQRVAIA 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 152 MILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGK-TVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK13635 153 GVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGiTVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEI 227

ABC_Pro_Gly_Betaine

cd03294

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...

14-228

8.89e-35

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 125.83 E-value: 8.89e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC-----------KVAFL 82
Cdd:cd03294   35 GQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRElrrkkismvfqSFALL 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVlpipegvNVRQLVAYGRSphnsLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:cd03294  115 PHR-------TVLENVAFGLE----VQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILL 183

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 163 LDEPTTYLD----ISHQVELLDLMRELsaeGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:cd03294  184 MDEAFSALDplirREMQDELLRLQAEL---QKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILT 250

PRK13537

nodulation factor ABC transporter ATP-binding protein NodI;

2-239

1.44e-34

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 126.07 E-value: 1.44e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQlSARELACKVAF 81
Cdd:PRK13537   6 APIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPS-RARHARQRVGV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQVLPIPEGVNVRQ-LVAYGRsphnsLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAI 160
Cdd:PRK13537  85 VPQFDNLDPDFTVREnLLVFGR-----YFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDV 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 161 VLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVH 239
Cdd:PRK13537 160 LVLDEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIESEIGCDVIEIY 238

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

3-232

1.83e-34

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 129.37 E-value: 1.83e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LACKVAF 81
Cdd:COG1129    4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDaQAAGIAI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQ-VLPIPEgVNVRQLVAYGRSPHNslWGRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQ-----RAwlamiL 154
Cdd:COG1129   84 IHQeLNLVPN-LSVAENIFLGREPRR--GGLIDWRAMRRrARELLARLGLDIDPDTPVGDLSVAQQQlveiaRA-----L 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 155 AQDAAIVLLDEPTTYLDiSHQVE-LLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELV 232
Cdd:COG1129  156 SRDARVLILDEPTASLT-EREVErLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAELTEDELV 233

cbiO

PRK13647

cobalt transporter ATP-binding subunit; Provisional

16-234

2.38e-34

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 124.85 E-value: 2.38e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  16 TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFlpqVLPIPE----G 91
Cdd:PRK13647  18 TKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVGL---VFQDPDdqvfS 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 VNVRQLVAYGrsPHNSlwgRLSGAD-QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYL 170
Cdd:PRK13647  95 STVWDDVAFG--PVNM---GLDKDEvERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYL 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 171 DISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQ 234
Cdd:PRK13647 170 DPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLTDEDIVEQ 233

ABC_NatA_sodium_exporter

cd03266

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...

19-221

2.74e-34

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.

Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 123.25 E-value: 2.74e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQlSARELACKVAFLPQVLPIPEGVNVRQLV 98
Cdd:cd03266   21 VDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVK-EPAEARRRLGFVSDSTGLYDRLTARENL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  99 AYgrsphnslWGRLSGADQHSVDQAL----QRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISH 174
Cdd:cd03266  100 EY--------FAGLYGLKGDELTARLeelaDRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMA 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 492172462 175 QVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03266  172 TRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218

PRK10851

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

1-226

3.53e-34

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 126.35 E-value: 3.53e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSIlKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELacKVA 80
Cdd:PRK10851   1 MSI-EIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDR--KVG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQVLPIPEGVNVRQLVAYGRS--PHNSlwgRLSGAD-QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQD 157
Cdd:PRK10851  78 FVFQHYALFRHMTVFDNIAFGLTvlPRRE---RPNAAAiKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVE 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 158 AAIVLLDEPTTYLDISHQVELLDLMRELSAEGK-TVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK10851 155 PQILLLDEPFGALDAQVRKELRRWLRQLHEELKfTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQV 224

ABC_subfamily_A

cd03263

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...

12-223

5.09e-34

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.

Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 122.23 E-value: 5.09e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDgkGYSQLSARELACK-VAFLPQVLPIPE 90
Cdd:cd03263   11 KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYIN--GYSIRTDRKAARQsLGYCPQFDALFD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 GVNVRQLVAYgrspHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYL 170
Cdd:cd03263   89 ELTVREHLRF----YARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGL 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 492172462 171 DISHQVELLDLMRELSaEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAP 223
Cdd:cd03263  165 DPASRRAIWDLILEVR-KGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSP 216

GlnQ

COG1126

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...

3-229

7.12e-34

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 122.41 E-value: 7.12e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK--GYSQLSARELACKVA 80
Cdd:COG1126    1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEdlTDSKKDINKLRRKVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQ---------VLpipEGVNVRQLVAYGRSPHNslwgrlsgADQHSVDQaLQRMELATLAERPLSDLSGGQRQRAWLA 151
Cdd:COG1126   81 MVFQqfnlfphltVL---ENVTLAPIKVKKMSKAE--------AEERAMEL-LERVGLADKADAYPAQLSGGQQQRVAIA 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 152 MILAQDAAIVLLDEPTTYLD---IShqvELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:COG1126  149 RALAMEPKVMLFDEPTSALDpelVG---EVLDVMRDLAKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFE 225


                 .
gi 492172462 229 A 229
Cdd:COG1126  226 N 226

MalK

COG3839

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...

1-226

4.20e-33

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];

Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 123.26 E-value: 4.20e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELacKVA 80
Cdd:COG3839    1 MASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDR--NIA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQ---VLPipeGVNVRQLVAYG---RsphnslwgRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMI 153
Cdd:COG3839   79 MVFQsyaLYP---HMTVYENIAFPlklR--------KVPKAEIDRrVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRA 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 154 LAQDAAIVLLDEPTTYLD----ISHQVELLDLMRELsaeGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:COG3839  148 LVREPKVFLLDEPLSNLDaklrVEMRAEIKRLHRRL---GTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEEL 221

CydD

TIGR02857

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...

14-212

4.31e-33

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD

Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 125.86 E-value: 4.31e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGvN 93
Cdd:TIGR02857 333 GRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAWVPQHPFLFAG-T 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   94 VRQLVAYGRsphnslwgrlSGADQHSVDQALQRMELATL-AERPL----------SDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:TIGR02857 412 IAENIRLAR----------PDASDAEIREALERAGLDEFvAALPQgldtpigeggAGLSGGQAQRLALARAFLRDAPLLL 481

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 492172462  163 LDEPTTYLDISHQVELLDLMRELsAEGKTVITVLHDINQACRyADHLAVM 212
Cdd:TIGR02857 482 LDEPTAHLDAETEAEVLEALRAL-AQGRTVLLVTHRLALAAL-ADRIVVL 529

TauB

COG1116

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...

1-218

6.36e-33

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 120.58 E-value: 6.36e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGY----GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARela 76
Cdd:COG1116    5 APALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPD--- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  77 ckVAFLPQ---VLPipegvNVRQLVAYGRsphnSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMI 153
Cdd:COG1116   82 --RGVVFQepaLLPw---lTVLDNVALGL----ELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARA 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 154 LAQDAAIVLLDEPTTYLD----ISHQVELLDLMRElsaEGKTVITVLHDINQACRYADHLAVMQG--GRLV 218
Cdd:COG1116  153 LANDPEVLLMDEPFGALDaltrERLQDELLRLWQE---TGKTVLFVTHDVDEAVFLADRVVVLSArpGRIV 220

cbiO

PRK13639

cobalt transporter ATP-binding subunit; Provisional

3-228

2.28e-32

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 119.80 E-value: 2.28e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGY-GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK--GYSQLSARELACKV 79
Cdd:PRK13639   1 ILETRDLKYSYpDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEpiKYDKKSLLEVRKTV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQ----VLPIPegvNVRQLVAYGrsPHNSlwgRLSGAD-QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMIL 154
Cdd:PRK13639  81 GIVFQnpddQLFAP---TVEEDVAFG--PLNL---GLSKEEvEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGIL 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 155 AQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:PRK13639 153 AMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFS 226

cbiO

PRK13632

cobalt transporter ATP-binding subunit; Provisional

18-230

2.79e-32

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 119.33 E-value: 2.79e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVlpiPE----GVN 93
Cdd:PRK13632  24 ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIRKKIGIIFQN---PDnqfiGAT 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 VRQLVAYG----RSPHNSLWGRlsgadqhsVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTY 169
Cdd:PRK13632 101 VEDDIAFGlenkKVPPKKMKDI--------IDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSM 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 170 LDISHQVELLDLMRELSAEG-KTVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:PRK13632 173 LDPKGKREIKKIMVDLRKTRkKTLISITHDMDEAIL-ADKVIVFSEGKLIAQGKPKEILNNK 233

ABC_ModC_molybdenum_transporter

cd03297

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...

21-218

3.64e-32

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 117.40 E-value: 3.64e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPPaGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYsqLSARELAC------KVAFLPQVLPIPEGVNV 94
Cdd:cd03297   16 KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVL--FDSRKKINlppqqrKIGLVFQQYALFPHLNV 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  95 RQLVAYGrsphnsLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISH 174
Cdd:cd03297   93 RENLAFG------LKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRAL 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 492172462 175 QVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:cd03297  167 RLQLLPELKQIKKNlNIPVIFVTHDLSEAEYLADRIVVMEDGRLQ 211

SunT

COG2274

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...

18-230

1.11e-31

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];

Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 123.02 E-value: 1.11e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGvNVRQL 97
Cdd:COG2274  490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLRRQIGVVLQDVFLFSG-TIREN 568

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  98 VAYGRsphnslwgrlSGADQHSVDQALQRMELATLAER-------PLSD----LSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:COG2274  569 ITLGD----------PDATDEEIIEAARLAGLHDFIEAlpmgydtVVGEggsnLSGGQRQRLAIARALLRNPRILILDEA 638

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 167 TTYLDISHQVELLDLMRELSAeGKTVITVLHDINQAcRYADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:COG2274  639 TSALDAETEAIILENLRRLLK-GRTVIIIAHRLSTI-RLADRIIVLDKGRIVEDGTHEELLARK 700

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

6-198

2.53e-31

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 120.94 E-value: 2.53e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   6 AQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelaCKVAFLPQV 85
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKG-----------LRIGYLPQE 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  86 LPIPEGVNVRQLVAYGRSPHNSLWGRL---------SGADQHSVDQALQRME--------------LATL------AERP 136
Cdd:COG0488   70 PPLDDDLTVLDTVLDGDAELRALEAELeeleaklaePDEDLERLAELQEEFEalggweaearaeeiLSGLgfpeedLDRP 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 137 LSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDIsHQVELLDlmRELSAEGKTVITVLHD 198
Cdd:COG0488  150 VSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDL-ESIEWLE--EFLKNYPGTVLVVSHD 208

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

3-218

3.62e-31

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 117.46 E-value: 3.62e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGY----GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQ---SGSLSLDGKGYSQLSAREL 75
Cdd:COG0444    1 LLEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPgitSGEILFDGEDLLKLSEKEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  76 ----ACKVAFLPQ--------VLPIpegvnvRQLVAYGRSPHnslwGRLSGADQHS-VDQALQRMELaTLAERPLSD--- 139
Cdd:COG0444   81 rkirGREIQMIFQdpmtslnpVMTV------GDQIAEPLRIH----GGLSKAEARErAIELLERVGL-PDPERRLDRyph 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 140 -LSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:COG0444  150 eLSGGMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRElGLAILFITHDLGVVAEIADRVAVMYAGRI 229


                 .
gi 492172462 218 V 218
Cdd:COG0444  230 V 230

ABC_PotA_N

cd03300

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...

13-226

4.45e-31

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 115.03 E-value: 4.45e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelackvaflpQVLPIP--- 89
Cdd:cd03300   10 YGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGK------------------DITNLPphk 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  90 EGVN-VRQlvAYGRSPHNSLW---------GRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDA 158
Cdd:cd03300   72 RPVNtVFQ--NYALFPHLTVFeniafglrlKKLPKAEIKErVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEP 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 159 AIVLLDEPTTYLDI----SHQVELLDLMRELsaeGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:cd03300  150 KVLLLDEPLGALDLklrkDMQLELKRLQKEL---GITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEI 218

ABC_DrrA

cd03265

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...

6-225

6.09e-31

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 114.39 E-value: 6.09e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   6 AQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLdgKGYSQLS-ARELACKVAFLPQ 84
Cdd:cd03265    3 VENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATV--AGHDVVRePREVRRRIGIVFQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 VLPIPEGVNVRQ-LVAYGRsphnsLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:cd03265   81 DLSVDDELTGWEnLYIHAR-----LYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462 164 DEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGD 225
Cdd:cd03265  156 DEPTIGLDPQTRAHVWEYIEKLKEEfGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEE 218

ABC_Carb_Monos_I

cd03216

First domain of the ATP-binding cassette component of monosaccharide transport system; This ...

4-218

6.10e-31

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 112.52 E-value: 6.10e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LACKVAFL 82
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRDaRRAGIAMV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQvlpipegvnvrqlvaygrsphnslwgrlsgadqhsvdqalqrmelatlaerplsdLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:cd03216   81 YQ-------------------------------------------------------LSVGERQMVEIARALARNARLLI 105

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:cd03216  106 LDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRVV 161

PRK14247

phosphate ABC transporter ATP-binding protein; Provisional

1-228

1.98e-30

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 113.85 E-value: 1.98e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARI--LTPQ---SGSLSLDGKGYSQLSAREL 75
Cdd:PRK14247   1 MNKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLieLYPEarvSGEVYLDGQDIFKMDVIEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  76 ACKVAFLPQVL-PIPEgVNVRQLVAYGRSphnslWGRLSGAD---QHSVDQALQRMEL-ATLAER---PLSDLSGGQRQR 147
Cdd:PRK14247  81 RRRVQMVFQIPnPIPN-LSIFENVALGLK-----LNRLVKSKkelQERVRWALEKAQLwDEVKDRldaPAGKLSGGQQQR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 148 AWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEgKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:PRK14247 155 LCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD-MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVF 233


                 .
gi 492172462 228 T 228
Cdd:PRK14247 234 T 234

TauB

COG4525

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

1-218

1.07e-29

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 112.26 E-value: 1.07e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYG----ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-- 74
Cdd:COG4525    1 MSMLTVRHVSVRYPgggqPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGADRgv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  75 LACKVAFLPQVlpipegvNVRQLVAYGRsphnslwgRLSGADQHS----VDQALQRMELATLAERPLSDLSGGQRQRAWL 150
Cdd:COG4525   81 VFQKDALLPWL-------NVLDNVAFGL--------RLRGVPKAErrarAEELLALVGLADFARRRIWQLSGGMRQRVGI 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 151 AMILAQDAAIVLLDEPTTYLDI----SHQVELLDLMRElsaEGKTVITVLHDINQACRYADHLAVMQG--GRLV 218
Cdd:COG4525  146 ARALAADPRFLLMDEPFGALDAltreQMQELLLDVWQR---TGKGVFLITHSVEEALFLATRLVVMSPgpGRIV 216

PRK13536

nodulation factor ABC transporter ATP-binding protein NodI;

13-239

1.14e-29

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 113.77 E-value: 1.14e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQlSARELACKVAFLPQVLPIPEGV 92
Cdd:PRK13536  51 YGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPA-RARLARARIGVVPQFDNLDLEF 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQ-LVAYGRsphnslWGRLSGADQHSVDQALqrMELATL---AERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:PRK13536 130 TVREnLLVFGR------YFGMSTREIEAVIPSL--LEFARLeskADARVSDLSGGMKRRLTLARALINDPQLLILDEPTT 201

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 169 YLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQVFDVH 239
Cdd:PRK13536 202 GLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALIDEHIGCQVIEIY 272

ABCC_bacteriocin_exporters

cd03245

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...

19-218

1.21e-29

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.

Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 111.14 E-value: 1.21e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGvNVRQLV 98
Cdd:cd03245   20 LDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIGYVPQDVTLFYG-TLRDNI 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  99 AYGRSPHNSL----WGRLSGADQHSVDQA--LQRMelatLAERPLSdLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDI 172
Cdd:cd03245   99 TLGAPLADDErilrAAELAGVTDFVNKHPngLDLQ----IGERGRG-LSGGQRQAVALARALLNDPPILLLDEPTSAMDM 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 492172462 173 SHQVELLDLMRELsAEGKTVITVLHDINqACRYADHLAVMQGGRLV 218
Cdd:cd03245  174 NSEERLKERLRQL-LGDKTLIIITHRPS-LLDLVDRIIVMDSGRIV 217

ABCC_Protease_Secretion

cd03246

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...

18-217

1.55e-29

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.

Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 109.23 E-value: 1.55e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQvlpipegvNVrQL 97
Cdd:cd03246   17 VLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVGYLPQ--------DD-EL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  98 vaygrsphnslwgrLSGadqhsvdqalqrmelaTLAErplSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVE 177
Cdd:cd03246   88 --------------FSG----------------SIAE---NILSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERA 134

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 492172462 178 LLDLMRELSAEGKTVITVLHDINqACRYADHLAVMQGGRL 217
Cdd:cd03246  135 LNQAIAALKAAGATRIVIAHRPE-TLASADRILVLEDGRV 173

cbiO

PRK13636

cobalt transporter ATP-binding subunit; Provisional

3-227

2.17e-29

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 111.86 E-value: 2.17e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYG-ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK--GYSQLSARELACKV 79
Cdd:PRK13636   5 ILKVEELNYNYSdGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKpiDYSRKGLMKLRESV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFlpqVLPIPE----GVNVRQLVAYG----RSPHNSLwgrlsgadQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLA 151
Cdd:PRK13636  85 GM---VFQDPDnqlfSASVYQDVSFGavnlKLPEDEV--------RKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 152 MILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:PRK13636 154 GVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230

MdlB

COG1132

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

12-221

3.04e-29

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 115.65 E-value: 3.04e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GYGATRIV-QDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQvlpipE 90
Cdd:COG1132  348 SYPGDRPVlKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQIGVVPQ-----D 422

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 GV----NVRQLVAYGRsphnslwgrlSGADQHSVDQALQRMELATLAERpLSD------------LSGGQRQRAWLAMIL 154
Cdd:COG1132  423 TFlfsgTIRENIRYGR----------PDATDEEVEEAAKAAQAHEFIEA-LPDgydtvvgergvnLSGGQRQRIAIARAL 491

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 155 AQDAAIVLLDEPTTYLDISHQVELLDLMRELSAeGKTVITVLHDINQAcRYADHLAVMQGGRLVTCG 221
Cdd:COG1132  492 LKDPPILILDEATSALDTETEALIQEALERLMK-GRTTIVIAHRLSTI-RNADRILVLDDGRIVEQG 556

cbiO

PRK13652

cobalt transporter ATP-binding subunit; Provisional

1-230

3.68e-29

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 111.05 E-value: 3.68e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGY-GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAckv 79
Cdd:PRK13652   1 MHLIETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVR--- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQVLPIPE----GVNVRQLVAYGrsPHNslWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILA 155
Cdd:PRK13652  78 KFVGLVFQNPDdqifSPTVEQDIAFG--PIN--LGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 156 QDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:PRK13652 154 MEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229

PRK13539

cytochrome c biogenesis protein CcmA; Provisional

18-197

4.69e-29

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 109.19 E-value: 4.69e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSAREL--------ACKVAFlpqvlpip 89
Cdd:PRK13539  17 LFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEAchylghrnAMKPAL-------- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  90 egvNVRQLVAYgrsphnslWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTY 169
Cdd:PRK13539  89 ---TVAENLEF--------WAAFLGGEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAA 157

                        170       180
                 ....*....|....*....|....*...
gi 492172462 170 LDISHQVELLDLMRELSAEGKTVITVLH 197
Cdd:PRK13539 158 LDAAAVALFAELIRAHLAQGGIVIAATH 185

ABC_BcrA_bacitracin_resist

cd03268

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...

4-218

6.04e-29

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.

Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 108.84 E-value: 6.04e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSA--RELACKV-- 79
Cdd:cd03268    1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEalRRIGALIea 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 -AFLPQVLpipegvnvrqlvayGRSpHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDA 158
Cdd:cd03268   81 pGFYPNLT--------------ARE-NLRLLARLLGIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNP 145

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 159 AIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:cd03268  146 DLLILDEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205

ModC

COG4148

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...

21-228

7.48e-29

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis

Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 112.12 E-value: 7.48e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgYSQLSARELackvaFLPqvlpiPE----GV---- 92
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGE-VLQDSARGI-----FLP-----PHrrriGYvfqe 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 -------NVRQLVAYGRsphnslWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDE 165
Cdd:COG4148   86 arlfphlSVRGNLLYGR------KRAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDE 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 166 PTTYLDISHQVELLDLMRELSAEGKT-VITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:COG4148  160 PLAALDLARKAEILPYLERLRDELDIpILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLS 223

ABCC_cytochrome_bd

cd03247

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...

4-221

1.71e-28

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.

Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 106.63 E-value: 1.71e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYG--ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSArELACKVAF 81
Cdd:cd03247    1 LSINNVSFSYPeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEK-ALSSLISV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQvlpipegvnvrqlvaygrSPHnsLWGrlsgadqhsvdqalqrmelATLAERPLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:cd03247   80 LNQ------------------RPY--LFD-------------------TTLRNNLGRRFSGGERQRLALARILLQDAPIV 120

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELsAEGKTVITVLHDInQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03247  121 LLDEPTVGLDPITERQLLSLIFEV-LKDKTLIWITHHL-TGIEHMDKILFLENGKIIMQG 178

thiQ

TIGR01277

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...

23-217

2.03e-28

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]

Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 107.64 E-value: 2.03e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   23 SFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAckVAFLPQVLPIPEGVNVRQLVAYGR 102
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQRP--VSMLFQENNLFAHLTVRQNIGLGL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  103 SPhnSLwgRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLM 182
Cdd:TIGR01277  96 HP--GL--KLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALV 171

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 492172462  183 RELSAEGK-TVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:TIGR01277 172 KQLCSERQrTLLMVTHHLSDARAIASQIAVVSQGKI 207

ABCG_White

cd03234

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...

17-221

2.23e-28

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.

Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 107.74 E-value: 2.23e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQ---SGSLSLDGKgysQLSARELACKVAFLPQVLPIPEGVN 93
Cdd:cd03234   21 RILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQILFNGQ---PRKPDQFQKCVAYVRQDDILLPGLT 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 VRQLVAYgrSPHNSLWGRLSGA--DQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:cd03234   98 VRETLTY--TAILRLPRKSSDAirKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLD 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 492172462 172 ISHQVELLDLMRELSAEGKTVITVLH----DInqaCRYADHLAVMQGGRLVTCG 221
Cdd:cd03234  176 SFTALNLVSTLSQLARRNRIVILTIHqprsDL---FRLFDRILLLSSGEIVYSG 226

ArtP

COG4161

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

1-221

3.97e-28

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 107.41 E-value: 3.97e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSIlKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSqlsarelackva 80
Cdd:COG4161    1 MSI-QLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFD------------ 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 fLPQVLPIPEGVNVRQLVA-----YGRSPHNSLWGRLSGA--------DQHSVDQA---LQRMELATLAER-PLSdLSGG 143
Cdd:COG4161   68 -FSQKPSEKAIRLLRQKVGmvfqqYNLWPHLTVMENLIEApckvlglsKEQAREKAmklLARLRLTDKADRfPLH-LSGG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 144 QRQRAWLAMILAQDAAIVLLDEPTTYLD--ISHQVelLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:COG4161  146 QQQRVAIARALMMEPQVLLFDEPTAALDpeITAQV--VEIIRELSQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQG 223

ABC_HisP_GlnQ

cd03262

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...

4-217

5.19e-28

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.

Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 106.46 E-value: 5.19e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSA--RELACKVAF 81
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKniNELRQKVGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQ---------VLpipEGVNVRQLVAYGRSPHNslwgrlsgADQHSVdQALQRMELATLAERPLSDLSGGQRQRAWLAM 152
Cdd:cd03262   81 VFQqfnlfphltVL---ENITLAPIKVKGMSKAE--------AEERAL-ELLEKVGLADKADAYPAQLSGGQQQRVAIAR 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 153 ILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:cd03262  149 ALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

3-218

6.25e-28

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 111.31 E-value: 6.25e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLdGKGysqlsarelaCKVAFL 82
Cdd:COG0488  315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GET----------VKIGYF 383

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVL-PIPEGVNVRQLVAYGRsphnslwgrlSGADQHSVDQALQRMelatL-----AERPLSDLSGGQRQRAWLAMILAQ 156
Cdd:COG0488  384 DQHQeELDPDKTVLDELRDGA----------PGGTEQEVRGYLGRF----LfsgddAFKPVGVLSGGEKARLALAKLLLS 449

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 157 DAAIVLLDEPTTYLDISHQVELLDLMRELsaEGkTVITVLHDinqacRY-----ADHLAVMQGGRLV 218
Cdd:COG0488  450 PPNVLLLDEPTNHLDIETLEALEEALDDF--PG-TVLLVSHD-----RYfldrvATRILEFEDGGVR 508

ArpD

COG4618

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...

14-227

8.20e-28

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];

Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 111.38 E-value: 8.20e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATR-IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGv 92
Cdd:COG4618  342 GSKRpILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRHIGYLPQDVELFDG- 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQLVAygrsphnslwgRLSGADQHSVDQAlqrmelATLA-------------ERPLSD----LSGGQRQRAWLAMILA 155
Cdd:COG4618  421 TIAENIA-----------RFGDADPEKVVAA------AKLAgvhemilrlpdgyDTRIGEggarLSGGQRQRIGLARALY 483

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 156 QDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINqACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:COG4618  484 GDPRLVVLDEPNSNLDDEGEAALAAAIRALKARGATVVVITHRPS-LLAAVDKLLVLRDGRVQAFGPRDEVL 554

ABC_ModC_like

cd03299

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...

19-227

1.39e-27

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 105.88 E-value: 1.39e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELacKVAFLPQVLPIPEGVNVRQLV 98
Cdd:cd03299   15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKR--DISYVPQNYALFPHMTVYKNI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  99 AYGRSphNSLWGRLSgaDQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVEL 178
Cdd:cd03299   93 AYGLK--KRKVDKKE--IERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKL 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 492172462 179 LDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:cd03299  169 REELKKIRKEfGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVF 218

glnQ

PRK09493

glutamine ABC transporter ATP-binding protein GlnQ;

13-228

1.72e-27

glutamine ABC transporter ATP-binding protein GlnQ;

Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 105.95 E-value: 1.72e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGkgysqLSARELACKVAFLPQvlpiPEGV 92
Cdd:PRK09493  11 FGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDG-----LKVNDPKVDERLIRQ----EAGM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQLVAYgrsPH-----NSLWG--RLSGAD-QHSVDQALQRMELATLAER----PlSDLSGGQRQRAWLAMILAQDAAI 160
Cdd:PRK09493  82 VFQQFYLF---PHltaleNVMFGplRVRGASkEEAEKQARELLAKVGLAERahhyP-SELSGGQQQRVAIARALAVKPKL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 161 VLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:PRK09493 158 MLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIK 225

urea_trans_UrtE

TIGR03410

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...

4-226

1.82e-27

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 105.68 E-value: 1.82e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACK-VAFL 82
Cdd:TIGR03410   1 LEVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERARAgIAYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   83 PQvlpipeGvnvRQLVAYGRSPHNSLWG--RLSGADQHSVDQALQRME-LATLAERPLSDLSGGQRQRAWLAMILAQDAA 159
Cdd:TIGR03410  81 PQ------G---REIFPRLTVEENLLTGlaALPRRSRKIPDEIYELFPvLKEMLGRRGGDLSGGQQQQLAIARALVTRPK 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462  160 IVLLDEPTTYLDISHQVELLDLMRELSAEGK-TVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:TIGR03410 152 LLLLDEPTEGIQPSIIKDIGRVIRRLRAEGGmAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219

ABCC_ATM1_transporter

cd03253

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...

8-227

1.94e-27

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 105.78 E-value: 1.94e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   8 HLDIGYGATR-IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDG---KGYSQLSARElacKVAFLP 83
Cdd:cd03253    5 NVTFAYDPGRpVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGqdiREVTLDSLRR---AIGVVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 Q--VLpipegVN--VRqlvaygrspHNSLWGRLSGADQHSVDQA--------LQRMELA---TLAERPLSdLSGGQRQRA 148
Cdd:cd03253   82 QdtVL-----FNdtIG---------YNIRYGRPDATDEEVIEAAkaaqihdkIMRFPDGydtIVGERGLK-LSGGEKQRV 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 149 WLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAeGKTVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDVL 227
Cdd:cd03253  147 AIARAILKNPPILLLDEATSALDTHTEREIQAALRDVSK-GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEELL 223

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

26-199

2.00e-27

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 110.26 E-value: 2.00e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  26 PPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDG---------KG------YSQLSARELacKVAFLPQ-VLPIP 89
Cdd:COG1245   96 PKKGKVTGILGPNGIGKSTALKILSGELKPNLGDYDEEPswdevlkrfRGtelqdyFKKLANGEI--KVAHKPQyVDLIP 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  90 EGV--NVRQLvaygrsphnslwgrLSGADQH-SVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:COG1245  174 KVFkgTVREL--------------LEKVDERgKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEP 239

                        170       180       190
                 ....*....|....*....|....*....|...
gi 492172462 167 TTYLDISHQVELLDLMRELSAEGKTVITVLHDI 199
Cdd:COG1245  240 SSYLDIYQRLNVARLIRELAEEGKYVLVVEHDL 272

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

1-229

2.59e-27

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 109.77 E-value: 2.59e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGA----TRIVQDLSFSPPAGQVTALIGPNGCGKS----TLLKAFARILTPQSGSLSLDGKGYSQLSA 72
Cdd:COG4172    4 MPLLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLGLSE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  73 RELaCKV-----AFLPQ--------VLPIpegvnVRQlVAYGRSPHnslwGRLSGAdqhsvdQALQRM-ELATL-----A 133
Cdd:COG4172   84 REL-RRIrgnriAMIFQepmtslnpLHTI-----GKQ-IAEVLRLH----RGLSGA------AARARAlELLERvgipdP 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 134 ERPLSD----LSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADH 208
Cdd:COG4172  147 ERRLDAyphqLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRElGMALLLITHDLGVVRRFADR 226

                        250       260
                 ....*....|....*....|.
gi 492172462 209 LAVMQGGRLVTCGAPGDVLTA 229
Cdd:COG4172  227 VAVMRQGEIVEQGPTAELFAA 247

ABCC_MsbA

cd03251

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...

7-230

3.27e-27

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 105.01 E-value: 3.27e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   7 QHLDIGYGATR--IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQ 84
Cdd:cd03251    4 KNVTFRYPGDGppVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLRRQIGLVSQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 VLPIPEGvNVRQLVAYGRsphnslwgrlSGADQHSVDQALQR-------MEL-----ATLAERPlSDLSGGQRQRAWLAM 152
Cdd:cd03251   84 DVFLFND-TVAENIAYGR----------PGATREEVEEAARAanahefiMELpegydTVIGERG-VKLSGGQRQRIAIAR 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 153 ILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSaEGKTVITVLHDINqACRYADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:cd03251  152 ALLKDPPILILDEATSALDTESERLVQAALERLM-KNRTTFVIAHRLS-TIENADRIVVLEDGKIVERGTHEELLAQG 227

artP

PRK11124

arginine transporter ATP-binding subunit; Provisional

1-221

4.77e-27

arginine transporter ATP-binding subunit; Provisional

Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 104.71 E-value: 4.77e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSIlKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSqLSARELACKVA 80
Cdd:PRK11124   1 MSI-QLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFD-FSKTPSDKAIR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQVLpipeGVNVRQlvaYGRSPHNSLWGRLSGA--------DQHSVDQA---LQRMELATLAER-PLSdLSGGQRQRA 148
Cdd:PRK11124  79 ELRRNV----GMVFQQ---YNLWPHLTVQQNLIEApcrvlglsKDQALARAeklLERLRLKPYADRfPLH-LSGGQQQRV 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 149 WLAMILAQDAAIVLLDEPTTYLD--ISHQVelLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:PRK11124 151 AIARALMMEPQVLLFDEPTAALDpeITAQI--VSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQG 223

thiQ

PRK10771

thiamine ABC transporter ATP-binding protein ThiQ;

23-234

4.97e-27

thiamine ABC transporter ATP-binding protein ThiQ;

Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 104.28 E-value: 4.97e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  23 SFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLS-ARElacKVAFLPQVLPIPEGVNVRQLVAYG 101
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPpSRR---PVSMLFQENNLFSHLTVAQNIGLG 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 102 RSPhnSLwgRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDL 181
Cdd:PRK10771  96 LNP--GL--KLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTL 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 492172462 182 MRELSAEGK-TVITVLHDINQACRYADHLAVMQGGRLVTCGApgdvlTAELVCQ 234
Cdd:PRK10771 172 VSQVCQERQlTLLMVSHSLEDAARIAPRSLVVADGRIAWDGP-----TDELLSG 220

cbiO

PRK13640

energy-coupling factor transporter ATPase;

2-226

6.63e-27

energy-coupling factor transporter ATPase;

Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 105.27 E-value: 6.63e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGYGATR--IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGS---LSLDGKGYSQLSARELA 76
Cdd:PRK13640   4 NIVEFKHVSFTYPDSKkpALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPnskITVDGITLTAKTVWDIR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  77 CKVAFlpqVLPIPE----GVNVRQLVAYG----RSPHNSLwgrlsgadQHSVDQALQRMELATLAERPLSDLSGGQRQRA 148
Cdd:PRK13640  84 EKVGI---VFQNPDnqfvGATVGDDVAFGlenrAVPRPEM--------IKIVRDVLADVGMLDYIDSEPANLSGGQKQRV 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 149 WLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQAcRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK13640 153 AIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKnNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEI 230

FtsE

COG2884

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

3-224

7.51e-27

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 103.59 E-value: 7.51e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATR-IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARElackVAF 81
Cdd:COG2884    1 MIRFENVSKRYPGGReALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRRE----IPY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQVLpipeGV---------------NVR-QLVAYGRSPHnslwgrlsgADQHSVDQALQRMELATLAERPLSDLSGGQR 145
Cdd:COG2884   77 LRRRI----GVvfqdfrllpdrtvyeNVAlPLRVTGKSRK---------EIRRRVREVLDLVGLSDKAKALPHELSGGEQ 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 146 QRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPG 224
Cdd:COG2884  144 QRVAIARALVNRPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGRLVRDEARG 222

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

17-218

9.30e-27

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 108.07 E-value: 9.30e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LACKVAFLPQVLP-IPEgVNV 94
Cdd:PRK11288  18 KALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAaLAAGVAIIYQELHlVPE-MTV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  95 RQLVAYGRSPHNSLWGRLSGADQHSVDQaLQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISH 174
Cdd:PRK11288  97 AENLYLGQLPHKGGIVNRRLLNYEAREQ-LEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSARE 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 492172462 175 QVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:PRK11288 176 IEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVFKDGRYV 219

type_I_sec_LssB

TIGR03375

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...

19-229

1.47e-26

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]

Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 108.03 E-value: 1.47e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGvNVRQLV 98
Cdd:TIGR03375 481 LDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADLRRNIGYVPQDPRLFYG-TLRDNI 559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   99 AYGRsPHnslwgrlsgADQHSVDQALQRMELATLA-------ERPLSD----LSGGQRQRAWLAMILAQDAAIVLLDEPT 167
Cdd:TIGR03375 560 ALGA-PY---------ADDEEILRAAELAGVTEFVrrhpdglDMQIGErgrsLSGGQRQAVALARALLRDPPILLLDEPT 629

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462  168 TYLDISHQVELLDLMRELSAeGKTVITVLHDiNQACRYADHLAVMQGGRLVTCGAPGDVLTA 229
Cdd:TIGR03375 630 SAMDNRSEERFKDRLKRWLA-GKTLVLVTHR-TSLLDLVDRIIVMDNGRIVADGPKDQVLEA 689

ABC_MetN_methionine_transporter

cd03258

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...

12-229

1.93e-26

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 103.04 E-value: 1.93e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELackVAFLPQVLPIPEG 91
Cdd:cd03258   14 TGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKEL---RKARRRIGMIFQH 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 VN------VRQLVAYgrsPHnSLWGrLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLD 164
Cdd:cd03258   91 FNllssrtVFENVAL---PL-EIAG-VPKAEIEErVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKVLLCD 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 165 EPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTA 229
Cdd:cd03258  166 EATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFAN 231

cbiO

PRK13648

cobalt transporter ATP-binding subunit; Provisional

2-226

2.06e-26

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 103.68 E-value: 2.06e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGY--GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKV 79
Cdd:PRK13648   6 SIIVFKNVSFQYqsDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKHI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFlpqVLPIPE----GVNVRQLVAYGRSPHNslwgrLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMIL 154
Cdd:PRK13648  86 GI---VFQNPDnqfvGSIVKYDVAFGLENHA-----VPYDEMHRrVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462 155 AQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGK-TVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK13648 158 ALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNiTIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEI 229

cbiO

PRK13643

energy-coupling factor transporter ATPase;

15-227

2.83e-26

energy-coupling factor transporter ATPase;

Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 104.05 E-value: 2.83e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  15 ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSL-DGKGYSQLSARELACKVAFLPQVLPIPEGV- 92
Cdd:PRK13643  18 ASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVgDIVVSSTSKQKEIKPVRKKVGVVFQFPESQl 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 ---NVRQLVAYGrsPHNslwgrLSGADQHSVDQALQRMELATLA----ERPLSDLSGGQRQRAWLAMILAQDAAIVLLDE 165
Cdd:PRK13643  98 feeTVLKDVAFG--PQN-----FGIPKEKAEKIAAEKLEMVGLAdefwEKSPFELSGGQMRRVAIAGILAMEPEVLVLDE 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 166 PTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:PRK13643 171 PTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232

cbiO

PRK13641

energy-coupling factor transporter ATPase;

21-228

3.02e-26

energy-coupling factor transporter ATPase;

Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 103.76 E-value: 3.02e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGY----SQLSARELACKVAFlpqVLPIPEGV---- 92
Cdd:PRK13641  25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItpetGNKNLKKLRKKVSL---VFQFPEAQlfen 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQLVAYGrsPHNslwgrLSGADQHSVDQALQRMELATLAERPLS----DLSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:PRK13641 102 TVLKDVEFG--PKN-----FGFSEDEAKEKALKWLKKVGLSEDLISkspfELSGGQMRRVAIAGVMAYEPEILCLDEPAA 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 169 YLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:PRK13641 175 GLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFS 234

type_I_sec_PrtD

TIGR01842

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...

14-229

3.23e-26

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 106.66 E-value: 3.23e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVN 93
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKHIGYLPQDVELFPGTV 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   94 VRQLVAYGRSPHNS---LWGRLSGAdqHSVDQALQRMELATLAERPlSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYL 170
Cdd:TIGR01842 409 AENIARFGENADPEkiiEAAKLAGV--HELILRLPDGYDTVIGPGG-ATLSGGQRQRIALARALYGDPKLVVLDEPNSNL 485

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462  171 DISHQVELLDLMRELSAEGKTVITVLHDINqACRYADHLAVMQGGRLVTCGAPGDVLTA 229
Cdd:TIGR01842 486 DEEGEQALANAIKALKARGITVVVITHRPS-LLGCVDKILVLQDGRIARFGERDEVLAK 543

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

26-199

4.30e-26

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 106.43 E-value: 4.30e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  26 PPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDG---------KG------YSQLSARELacKVAFLPQ-VLPIP 89
Cdd:PRK13409  96 PKEGKVTGILGPNGIGKTTAVKILSGELIPNLGDYEEEPswdevlkrfRGtelqnyFKKLYNGEI--KVVHKPQyVDLIP 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  90 EGV--NVRQLvaygrsphnslwgrLSGADQHSV-DQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:PRK13409 174 KVFkgKVREL--------------LKKVDERGKlDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEP 239

                        170       180       190
                 ....*....|....*....|....*....|...
gi 492172462 167 TTYLDISHQVELLDLMRELsAEGKTVITVLHDI 199
Cdd:PRK13409 240 TSYLDIRQRLNVARLIREL-AEGKYVLVVEHDL 271

CydC

TIGR02868

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...

4-198

5.48e-26

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.

Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 105.91 E-value: 5.48e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    4 LKAQHLDIGY-GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFL 82
Cdd:TIGR02868 335 LELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSVC 414

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   83 PQVlPIPEGVNVRQLVAYGRsphnslwgrlSGADQHSVDQALQRMELATLAERpLSD------------LSGGQRQRAWL 150
Cdd:TIGR02868 415 AQD-AHLFDTTVRENLRLAR----------PDATDEELWAALERVGLADWLRA-LPDgldtvlgeggarLSGGERQRLAL 482

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 492172462  151 AMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSaEGKTVITVLHD 198
Cdd:TIGR02868 483 ARALLADAPILLLDEPTEHLDAETADELLEDLLAAL-SGRTVVLITHH 529

PRK14243

phosphate transporter ATP-binding protein; Provisional

3-210

5.68e-26

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 102.55 E-value: 5.68e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARI--LTPQ---SGSLSLDGKGY--SQLSAREL 75
Cdd:PRK14243  10 VLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLndLIPGfrvEGKVTFHGKNLyaPDVDPVEV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  76 ACKVAFLPQVlPIPEGVNVRQLVAYGrSPHNSLWGRLSGADQHSVDQALQRMELA-TLAERPLSdLSGGQRQRAWLAMIL 154
Cdd:PRK14243  90 RRRIGMVFQK-PNPFPKSIYDNIAYG-ARINGYKGDMDELVERSLRQAALWDEVKdKLKQSGLS-LSGGQQQRLCIARAI 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 155 AQDAAIVLLDEPTTYLDISHQVELLDLMRELSaEGKTVITVLHDINQACRYADHLA 210
Cdd:PRK14243 167 AVQPEVILMDEPCSALDPISTLRIEELMHELK-EQYTIIIVTHNMQQAARVSDMTA 221

PRK11160

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

4-221

6.05e-26

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 106.06 E-value: 6.05e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGY--GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAF 81
Cdd:PRK11160 339 LTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQAISV 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQvlpipegvnvrqlvaygrSPH---NSLWGRLSGADQHSVD----QALQRMELATLAE-------------RPlsdLS 141
Cdd:PRK11160 419 VSQ------------------RVHlfsATLRDNLLLAAPNASDealiEVLQQVGLEKLLEddkglnawlgeggRQ---LS 477

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 142 GGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELsAEGKTVITVLHDINqACRYADHLAVMQGGRLVTCG 221
Cdd:PRK11160 478 GGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEH-AQNKTVLMITHRLT-GLEQFDRICVMDNGQIIEQG 555

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

13-232

6.30e-26

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 105.88 E-value: 6.30e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LACKVAFLPQVLPIPEG 91
Cdd:COG3845   15 FGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRDaIALGIGMVHQHFMLVPN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 VNVRQLVAYGRSPHNSLWGRLSGADQHsVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:COG3845   95 LTVAENIVLGLEPTKGGRLDRKAARAR-IRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARILILDEPTAVLT 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 172 ISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELV 232
Cdd:COG3845  174 PQEADELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAETSEEELA 234

ABC_RNaseL_inhibitor_domain1

cd03236

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

25-199

9.84e-26

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 101.67 E-value: 9.84e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  25 SPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLS--------LDGKGYSQL-----SARELACKVAFLPQ-VLPIPE 90
Cdd:cd03236   22 VPREGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDdppdwdeiLDEFRGSELqnyftKLLEGDVKVIVKPQyVDLIPK 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 GV--NVRQLvaygrsphnslwgrLSGADQ-HSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPT 167
Cdd:cd03236  102 AVkgKVGEL--------------LKKKDErGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPS 167

                        170       180       190
                 ....*....|....*....|....*....|..
gi 492172462 168 TYLDISHQVELLDLMRELSAEGKTVITVLHDI 199
Cdd:cd03236  168 SYLDIKQRLNAARLIRELAEDDNYVLVVEHDL 199

modC_ABC

TIGR02142

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...

21-227

1.14e-25

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]

Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 103.27 E-value: 1.14e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   21 DLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSqlSARELAC------KVAFLPQVLPIPEGVNV 94
Cdd:TIGR02142  15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLF--DSRKGIFlppekrRIGYVFQEARLFPHLSV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   95 RQLVAYGRSphnslwgRLSGADQHSVDQALQRM-ELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDIS 173
Cdd:TIGR02142  93 RGNLRYGMK-------RARPSERRISFERVIELlGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDP 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 492172462  174 HQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:TIGR02142 166 RKYEILPYLERLHAEfGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVW 220

potA

TIGR01187

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...

34-223

1.30e-25

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 102.57 E-value: 1.30e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   34 LIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLpIPEgVNVRQLVAYGRsphnslwgRLS 113
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHLRHINMVFQSYAL-FPH-MTVEENVAFGL--------KMR 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  114 GADQHSVD----QALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDIS----HQVELLDLMREL 185
Cdd:TIGR01187  71 KVPRAEIKprvlEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKlrdqMQLELKTIQEQL 150

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 492172462  186 saeGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAP 223
Cdd:TIGR01187 151 ---GITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTP 185

ABC_MalK_N

cd03301

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...

13-221

1.43e-25

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.

Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 100.02 E-value: 1.43e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFlpQVLPIPEGV 92
Cdd:cd03301   10 FGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVF--QNYALYPHM 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQLVAYGRsphnslwgRLSGADQHSVDQALQR----MELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:cd03301   88 TVYDNIAFGL--------KLRKVPKDEIDERVREvaelLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLS 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 169 YLD----ISHQVELLDLMRELsaeGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03301  160 NLDaklrVQMRAELKRLQQRL---GTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213

TagH

COG1134

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...

17-229

1.53e-25

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 100.93 E-value: 1.53e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK---------GY-SQLSARElackvaflpqvl 86
Cdd:COG1134   40 WALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRvsallelgaGFhPELTGRE------------ 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  87 pipegvNVRqlvaygrsphnsLWGRLSGADQHSVDQALQRM-ELATLAE---RPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:COG1134  108 ------NIY------------LNGRLLGLSRKEIDEKFDEIvEFAELGDfidQPVKTYSSGMRARLAFAVATAVDPDILL 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTA 229
Cdd:COG1134  170 VDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAA 236

potG

PRK11607

putrescine ABC transporter ATP-binding subunit PotG;

3-226

1.85e-25

putrescine ABC transporter ATP-binding subunit PotG;

Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 103.38 E-value: 1.85e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFL 82
Cdd:PRK11607  19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMFQ 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLpIPEgVNVRQLVAYG----RSPHNSLWGRlsgadqhsVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDA 158
Cdd:PRK11607  99 SYAL-FPH-MTVEQNIAFGlkqdKLPKAEIASR--------VNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRP 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 159 AIVLLDEPTTYLDIS----HQVELLDLMRELsaeGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK11607 169 KLLLLDEPMGALDKKlrdrMQLEVVDILERV---GVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237

tauB

PRK11248

taurine ABC transporter ATP-binding subunit;

3-227

2.09e-25

taurine ABC transporter ATP-binding subunit;

Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 100.54 E-value: 2.09e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARElacKVAFL 82
Cdd:PRK11248   1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER---GVVFQ 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLpIPeGVNVRQLVAYGRsphnSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:PRK11248  78 NEGL-LP-WRNVQDNVAFGL----QLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLL 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGrlvtcgaPGDVL 227
Cdd:PRK11248 152 LDEPFGALDAFTREQMQTLLLKLWQEtGKQVLLITHDIEEAVFMATELVLLSPG-------PGRVV 210

ABCC_TAP

cd03248

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...

15-217

2.13e-25

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.

Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 99.85 E-value: 2.13e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  15 ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVlPIPEGVNV 94
Cdd:cd03248   26 DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHSKVSLVGQE-PVLFARSL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  95 RQLVAYG--RSPHNSLWGRLSGADQHSVDQALQRmELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDI 172
Cdd:cd03248  105 QDNIAYGlqSCSFECVKEAAQKAHAHSFISELAS-GYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDA 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 492172462 173 SHQVELLDLMRElSAEGKTVITVLHDINQACRyADHLAVMQGGRL 217
Cdd:cd03248  184 ESEQQVQQALYD-WPERRTVLVIAHRLSTVER-ADQILVLDGGRI 226

cbiO

PRK13638

energy-coupling factor ABC transporter ATP-binding protein;

22-256

2.51e-25

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 100.85 E-value: 2.51e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  22 LSFSPPAgqVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKG--YSQLSARELACKVAflpQVLPIPEG----VNVR 95
Cdd:PRK13638  22 LDFSLSP--VTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPldYSKRGLLALRQQVA---TVFQDPEQqifyTDID 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  96 QLVAYgrSPHNslWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQ 175
Cdd:PRK13638  97 SDIAF--SLRN--LGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGR 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 176 VELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT-AELVCQ-------VFDVHVQImrepv 247
Cdd:PRK13638 173 TQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFAcTEAMEQagltqpwLVKLHTQL----- 247


                 ....*....
gi 492172462 248 aGTPMCIVE 256
Cdd:PRK13638 248 -GLPLCKTE 255

ABCC_Glucan_exporter_like

cd03254

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...

12-227

2.64e-25

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 99.61 E-value: 2.64e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GYGATRIV-QDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPE 90
Cdd:cd03254   11 SYDEKKPVlKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSMIGVVLQDTFLFS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 GvNVRQLVAYGRsphnslwgrlSGADQHSVDQALQRMELATLAERpL------------SDLSGGQRQRAWLAMILAQDA 158
Cdd:cd03254   91 G-TIMENIRLGR----------PNATDEEVIEAAKEAGAHDFIMK-LpngydtvlgengGNLSQGERQLLAIARAMLRDP 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 159 AIVLLDEPTTYLDISHQVELLDLMRELSaEGKTVITVLHDINqACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:cd03254  159 KILILDEATSNIDTETEKLIQEALEKLM-KGRTSIIIAHRLS-TIKNADKILVLDDGKIIEEGTHDELL 225

phnK

PRK11701

phosphonate C-P lyase system protein PhnK; Provisional

3-227

4.13e-25

phosphonate C-P lyase system protein PhnK; Provisional

Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 100.00 E-value: 4.13e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQlsaRELACkvafl 82
Cdd:PRK11701   6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQL---RDLYA----- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 pqvLPIPE---------GVnVRQLVAYGRSPHNSLWG----RLSGA-DQH------SVDQALQRMELAtlAERpLSDL-- 140
Cdd:PRK11701  78 ---LSEAErrrllrtewGF-VHQHPRDGLRMQVSAGGnigeRLMAVgARHygdiraTAGDWLERVEID--AAR-IDDLpt 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 141 --SGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:PRK11701 151 tfSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRElGLAVVIVTHDLAVARLLAHRLLVMKQGRV 230

                        250
                 ....*....|
gi 492172462 218 VTCGAPGDVL 227
Cdd:PRK11701 231 VESGLTDQVL 240

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

3-229

5.68e-25

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 103.23 E-value: 5.68e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGY-----------GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARiLTPQSGSLSLDGKGYSQLS 71
Cdd:COG4172  275 LLEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLR-LIPSEGEIRFDGQDLDGLS 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  72 ARELackvafLP-----QVlpipegV------------NVRQLVAYGRSPHNSlwgRLSGADQHS-VDQALQRMEL-ATL 132
Cdd:COG4172  354 RRAL------RPlrrrmQV------VfqdpfgslsprmTVGQIIAEGLRVHGP---GLSAAERRArVAEALEEVGLdPAA 418

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 133 AERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDInQACRY-ADHLA 210
Cdd:COG4172  419 RHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREhGLAYLFISHDL-AVVRAlAHRVM 497

                        250
                 ....*....|....*....
gi 492172462 211 VMQGGRLVTCGAPGDVLTA 229
Cdd:COG4172  498 VMKDGKVVEQGPTEQVFDA 516

YnjD

COG4136

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...

4-225

6.10e-25

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];

Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 98.32 E-value: 6.10e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQ---SGSLSLDGKGYSQLSARELacKVA 80
Cdd:COG4136    2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRLTALPAEQR--RIG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQVLPIPEGVNVRQLVAYGrsphnsLWGRLSGAD-QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLA-MILAQDA 158
Cdd:COG4136   80 ILFQDDLLFPHLSVGENLAFA------LPPTIGRAQrRARVEQALEEAGLAGFADRDPATLSGGQRARVALLrALLAEPR 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 159 AiVLLDEPTTYLDISHQVELLDLMRE-LSAEGKTVITVLHDINqacryadhlAVMQGGRLVTCGAPGD 225
Cdd:COG4136  154 A-LLLDEPFSKLDAALRAQFREFVFEqIRQRGIPALLVTHDEE---------DAPAAGRVLDLGNWQH 211

ABC_NatA_like

cd03267

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...

19-218

8.38e-25

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.

Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 98.56 E-value: 8.38e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK-GYSQlsARELACKVAFL----PQV---LPIPE 90
Cdd:cd03267   37 LKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLvPWKR--RKKFLRRIGVVfgqkTQLwwdLPVID 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 GVNVRQLVaYGRSPhnslwgrlsGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYL 170
Cdd:cd03267  115 SFYLLAAI-YDLPP---------ARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGL 184

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 492172462 171 DISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:cd03267  185 DVVAQENIRNFLKEYNRErGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233

ABC_MTABC3_MDL1_MDL2

cd03249

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...

18-218

1.19e-24

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.

Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 98.38 E-value: 1.19e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVlPIPEGVNVRQL 97
Cdd:cd03249   18 ILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQIGLVSQE-PVLFDGTIAEN 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  98 VAYGRSPhnslwgrlsgADQHSVDQALQR-------MELA----TLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:cd03249   97 IRYGKPD----------ATDEEVEEAAKKanihdfiMSLPdgydTLVGERGSQLSGGQKQRIAIARALLRNPKILLLDEA 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 167 TTYLD-ISHQV--ELLDLMRelsaEGKTVITVLHDINqACRYADHLAVMQGGRLV 218
Cdd:cd03249  167 TSALDaESEKLvqEALDRAM----KGRTTIVIAHRLS-TIRNADLIAVLQNGQVV 216

ABCF_EF-3

cd03221

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...

4-203

1.51e-24

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.

Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 95.21 E-value: 1.51e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelaCKVAFLP 83
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGST-----------VKIGYFE 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QvlpipegvnvrqlvaygrsphnslwgrlsgadqhsvdqalqrmelatlaerplsdLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:cd03221   70 Q-------------------------------------------------------LSGGEKMRLALAKLLLENPNLLLL 94

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 492172462 164 DEPTTYLDISHQVELLDLMRELSaegKTVITVLHD---INQAC 203
Cdd:cd03221   95 DEPTNHLDLESIEALEEALKEYP---GTVILVSHDryfLDQVA 134

ABCG_EPDR

cd03213

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...

12-221

1.99e-24

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.

Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 96.47 E-value: 1.99e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFA--RILTPQSGSLSLDGKgysQLSARELACKVAFLPQvlpip 89
Cdd:cd03213   18 SKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAgrRTGLGVSGEVLINGR---PLDKRSFRKIIGYVPQ----- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  90 egvnvrqlvaygrspHNSLWGRLSgadqhsVDQALQrmeLAtlAErpLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTY 169
Cdd:cd03213   90 ---------------DDILHPTLT------VRETLM---FA--AK--LRGLSGGERKRVSIALELVSNPSLLFLDEPTSG 141

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 170 LDISHQVELLDLMRELSAEGKTVITVLH----DINQACryaDHLAVMQGGRLVTCG 221
Cdd:cd03213  142 LDSSSALQVMSLLRRLADTGRTIICSIHqpssEIFELF---DKLLLLSQGRVIYFG 194

cbiO

PRK13649

energy-coupling factor transporter ATPase;

17-226

2.39e-24

energy-coupling factor transporter ATPase;

Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 98.28 E-value: 2.39e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSA----RELACKVAFlpqVLPIPEGV 92
Cdd:PRK13649  21 RALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKnkdiKQIRKKVGL---VFQFPESQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 ----NVRQLVAYGrsPHNSlwgrlsGADQHSVdQALQRMELA------TLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:PRK13649  98 lfeeTVLKDVAFG--PQNF------GVSQEEA-EALAREKLAlvgiseSLFEKNPFELSGGQMRRVAIAGILAMEPKILV 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK13649 169 LDEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDI 232

PRK14239

phosphate transporter ATP-binding protein; Provisional

3-221

2.41e-24

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 97.92 E-value: 2.41e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARI--LTPQ---SGSLSLDGKG-YS-QLSAREL 75
Cdd:PRK14239   5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndLNPEvtiTGSIVYNGHNiYSpRTDTVDL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  76 ACKVAFLPQvLPIPEGVNVRQLVAYGRsphnslwgRLSGA-DQHSVDQALQR-MELATLAER---PLSD----LSGGQRQ 146
Cdd:PRK14239  85 RKEIGMVFQ-QPNPFPMSIYENVVYGL--------RLKGIkDKQVLDEAVEKsLKGASIWDEvkdRLHDsalgLSGGQQQ 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 147 RAWLAMILAQDAAIVLLDEPTTYLD-ISH-QVE--LLDLMRELsaegkTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:PRK14239 156 RVCIARVLATSPKIILLDEPTSALDpISAgKIEetLLGLKDDY-----TMLLVTRSMQQASRISDRTGFFLDGDLIEYN 229

LolD_lipo_ex

TIGR02211

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...

15-218

3.64e-24

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 96.65 E-value: 3.64e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   15 ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC----KVAFLPQVLPIPE 90
Cdd:TIGR02211  17 DTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNERAKlrnkKLGFIYQFHHLLP 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   91 GVNVRQLVAYgrsPhnSLWGRLSGADQHSVDQA-LQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTY 169
Cdd:TIGR02211  97 DFTALENVAM---P--LLIGKKSVKEAKERAYEmLEKVGLEHRINHRPSELSGGERQRVAIARALVNQPSLVLADEPTGN 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 492172462  170 LDISHQVELLDLMRELSAEGKT-VITVLHDINQACRyADHLAVMQGGRLV 218
Cdd:TIGR02211 172 LDNNNAKIIFDLMLELNRELNTsFLVVTHDLELAKK-LDRVLEMKDGQLF 220

cbiO

PRK13634

cobalt transporter ATP-binding subunit; Provisional

15-226

3.98e-24

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 98.17 E-value: 3.98e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  15 ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSL------DGKGYSQLsaRELACKVAFlpqVLPI 88
Cdd:PRK13634  19 ERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIgervitAGKKNKKL--KPLRKKVGI---VFQF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  89 PEgvnvRQL--------VAYGrsPHNSlwgrlsGAdqhSVDQALQR----MELATLAERPLS----DLSGGQRQRAWLAM 152
Cdd:PRK13634  94 PE----HQLfeetvekdICFG--PMNF------GV---SEEDAKQKaremIELVGLPEELLArspfELSGGQMRRVAIAG 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 153 ILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK13634 159 VLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEkGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREI 233

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

29-199

5.09e-24

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 100.65 E-value: 5.09e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDgkgysqlsarelaCKVAFLPQVLPIPEGVNVRQL-----VAYGRS 103
Cdd:PRK13409 365 GEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE-------------LKISYKPQYIKPDYDGTVEDLlrsitDDLGSS 431

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 104 PHNSlwgrlsgadqhsvdQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMR 183
Cdd:PRK13409 432 YYKS--------------EIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIR 497

                        170
                 ....*....|....*..
gi 492172462 184 ELSAE-GKTVITVLHDI 199
Cdd:PRK13409 498 RIAEErEATALVVDHDI 514

PRK14246

phosphate ABC transporter ATP-binding protein; Provisional

18-229

5.96e-24

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 97.04 E-value: 5.96e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK------GYSQLSARELACKVAFL-PQVLPIPE 90
Cdd:PRK14246  25 ILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKvlyfgkDIFQIDAIKLRKEVGMVfQQPNPFPH 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 gVNVRQLVAYGRSPHNSLWGRlsgADQHSVDQALQRM----ELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:PRK14246 105 -LSIYDNIAYPLKSHGIKEKR---EIKKIVEECLRKVglwkEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEP 180

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462 167 TTYLDISHQVELLDLMRELSAEgKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTA 229
Cdd:PRK14246 181 TSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTS 242

3a01208

TIGR00958

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

18-221

7.94e-24

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 100.18 E-value: 7.94e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVlPIPEGVNVRQL 97
Cdd:TIGR00958 496 VLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHRQVALVGQE-PVLFSGSVREN 574

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   98 VAYG--RSPHNSLwgrLSGADQHSVDQALQRME--LATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDIS 173
Cdd:TIGR00958 575 IAYGltDTPDEEI---MAAAKAANAHDFIMEFPngYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAE 651

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 492172462  174 HQVELLDLMrelSAEGKTVITVLHDInQACRYADHLAVMQGGRLVTCG 221
Cdd:TIGR00958 652 CEQLLQESR---SRASRTVLLIAHRL-STVERADQILVLKKGSVVEMG 695

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

13-232

1.66e-23

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 99.09 E-value: 1.66e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLS---ARELACKVAFlpQVLPIP 89
Cdd:PRK09700  15 FGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDhklAAQLGIGIIY--QELSVI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  90 EGVNVRQLVAYGRSPHNSLWGrLSGAD----QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDE 165
Cdd:PRK09700  93 DELTVLENLYIGRHLTKKVCG-VNIIDwremRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDE 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 166 PTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELV 232
Cdd:PRK09700 172 PTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDVSNDDIV 238

PRK14267

phosphate ABC transporter ATP-binding protein; Provisional

4-221

4.19e-23

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 94.52 E-value: 4.19e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQ-----SGSLSLDGKG-YS-QLSARELA 76
Cdd:PRK14267   5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNiYSpDVDPIEVR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  77 CKVAFLPQVL-PIPEgVNVRQLVAYGRSPHNSLWGRlsGADQHSVDQALQRMELATLAERPLSD----LSGGQRQRAWLA 151
Cdd:PRK14267  85 REVGMVFQYPnPFPH-LTIYDNVAIGVKLNGLVKSK--KELDERVEWALKKAALWDEVKDRLNDypsnLSGGQRQRLVIA 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 152 MILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEgKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:PRK14267 162 RALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE-YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVG 230

PRK10247

putative ABC transporter ATP-binding protein YbbL; Provisional

3-202

4.71e-23

putative ABC transporter ATP-binding protein YbbL; Provisional

Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 93.63 E-value: 4.71e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFL 82
Cdd:PRK10247   7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQVSYC 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVlPIPEGVNVRQLVAYgrsPhnslWG-RLSGADQHSVDQALQRMELA-TLAERPLSDLSGGQRQRAWLAMILAQDAAI 160
Cdd:PRK10247  87 AQT-PTLFGDTVYDNLIF---P----WQiRNQQPDPAIFLDDLERFALPdTILTKNIAELSGGEKQRISLIRNLQFMPKV 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 492172462 161 VLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHD---INQA 202
Cdd:PRK10247 159 LLLDEITSALDESNKHNVNEIIHRYVREqNIAVLWVTHDkdeINHA 204

ABC_RNaseL_inhibitor_domain2

cd03237

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

29-214

5.07e-23

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 94.01 E-value: 5.07e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelacKVAFLPQVLPIPEGVNVRQLvaygrsphnsL 108
Cdd:cd03237   25 SEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELD------------TVSYKPQYIKADYEGTVRDL----------L 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 109 WGRLSGADQHS--VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELS 186
Cdd:cd03237   83 SSITKDFYTHPyfKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFA 162

                        170       180
                 ....*....|....*....|....*....
gi 492172462 187 AEG-KTVITVLHDINQACRYADHLAVMQG 214
Cdd:cd03237  163 ENNeKTAFVVEHDIIMIDYLADRLIVFEG 191

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

29-199

6.72e-23

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 97.55 E-value: 6.72e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDgkgysqlsarelaCKVAFLPQVLPIPEGVNVRQLV--AYGRSPHN 106
Cdd:COG1245  366 GEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDED-------------LKISYKPQYISPDYDGTVEEFLrsANTDDFGS 432

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 107 SLWgrlsgadQHSVdqaLQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELS 186
Cdd:COG1245  433 SYY-------KTEI---IKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFA 502

                        170
                 ....*....|....
gi 492172462 187 AE-GKTVITVLHDI 199
Cdd:COG1245  503 ENrGKTAMVVDHDI 516

PRK10070

proline/glycine betaine ABC transporter ATP-binding protein ProV;

19-227

7.78e-23

proline/glycine betaine ABC transporter ATP-binding protein ProV;

Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 96.26 E-value: 7.78e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELA----CKVAFLPQVLPIPEGVNV 94
Cdd:PRK10070  44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRevrrKKIAMVFQSFALMPHMTV 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  95 RQLVAYGRSphnsLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISH 174
Cdd:PRK10070 124 LDNTAFGME----LAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLI 199

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 492172462 175 QVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:PRK10070 200 RTEMQDELVKLQAKhQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253

PRK11000

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

13-223

9.77e-23

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 95.48 E-value: 9.77e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelackvaFLPQVLPIPEGV 92
Cdd:PRK11000  13 YGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEK---------------RMNDVPPAERGV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 N-VRQlvAYGRSPHNSL-----WG-RLSGAD----QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:PRK11000  78 GmVFQ--SYALYPHLSVaenmsFGlKLAGAKkeeiNQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVF 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 162 LLDEPTTYLD----ISHQVELLDLMRELsaeGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAP 223
Cdd:PRK11000 156 LLDEPLSNLDaalrVQMRIEISRLHKRL---GRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP 218

bacteriocin_ABC

TIGR01193

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...

4-227

1.09e-22

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]

Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 97.12 E-value: 1.09e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    4 LKAQHLDIGYG-ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFL 82
Cdd:TIGR01193 474 IVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLRQFINYL 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   83 PQVLPIPEGVNVRQLvaygrsphnsLWGRLSGADQHSVDQALQRMELATLAER-PL----------SDLSGGQRQRAWLA 151
Cdd:TIGR01193 554 PQEPYIFSGSILENL----------LLGAKENVSQDEIWAACEIAEIKDDIENmPLgyqtelseegSSISGGQKQRIALA 623

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462  152 MILAQDAAIVLLDEPTTYLDISHQVELLDLMreLSAEGKTVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDVL 227
Cdd:TIGR01193 624 RALLTDSKVLILDESTSNLDTITEKKIVNNL--LNLQDKTIIFVAHRLSVAKQ-SDKIIVLDHGKIIEQGSHDELL 696

cbiO

PRK13637

energy-coupling factor transporter ATPase;

1-226

1.21e-22

energy-coupling factor transporter ATPase;

Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 93.96 E-value: 1.21e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSIlKAQHLDIGYG-----ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYS--QLSAR 73
Cdd:PRK13637   1 MSI-KIENLTHIYMegtpfEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITdkKVKLS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  74 ELACKVAFlpqVLPIPEgvnvRQL--------VAYGrsPHNslwgrLSGADQHSVDQALQRMELA-----TLAERPLSDL 140
Cdd:PRK13637  80 DIRKKVGL---VFQYPE----YQLfeetiekdIAFG--PIN-----LGLSEEEIENRVKRAMNIVgldyeDYKDKSPFEL 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 141 SGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGK-TVITVLHDINQACRYADHLAVMQGGRLVT 219
Cdd:PRK13637 146 SGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNmTIILVSHSMEDVAKLADRIIVMNKGKCEL 225


                 ....*..
gi 492172462 220 CGAPGDV 226
Cdd:PRK13637 226 QGTPREV 232

ABC_YhbG

cd03218

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...

4-236

1.31e-22

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.

Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 92.61 E-value: 1.31e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACK-VAFL 82
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLgIGYL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLPIPEGVNVRQ---LVAYGRsphnslwgRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDA 158
Cdd:cd03218   81 PQEASIFRKLTVEEnilAVLEIR--------GLSKKEREEkLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNP 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 159 AIVLLDEPTTYLD-ISHQvELLDLMRELSAEGktvITVL---HDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQ 234
Cdd:cd03218  153 KFLLLDEPFAGVDpIAVQ-DIQKIIKILKDRG---IGVLitdHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANELVRK 228


                 ..
gi 492172462 235 VF 236
Cdd:cd03218  229 VY 230

ABC_KpsT_Wzt

cd03220

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...

17-221

3.01e-22

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.

Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 91.44 E-value: 3.01e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK---------GY-SQLSARElackvaflpqvl 86
Cdd:cd03220   36 WALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRvssllglggGFnPELTGRE------------ 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  87 pipegvNVRqlvaygrsphnsLWGRLSGADQHSVDQALQRM-ELATLAE---RPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:cd03220  104 ------NIY------------LNGRLLGLSRKEIDEKIDEIiEFSELGDfidLPVKTYSSGMKARLAFAIATALEPDILL 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:cd03220  166 IDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224

potA

PRK09452

spermidine/putrescine ABC transporter ATP-binding protein PotA;

1-226

3.05e-22

spermidine/putrescine ABC transporter ATP-binding protein PotA;

Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 94.24 E-value: 3.05e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVA 80
Cdd:PRK09452  12 SPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQVLpIPEgVNVRQLVAYG----RSPHNSLWGRlsgadqhsVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQ 156
Cdd:PRK09452  92 FQSYAL-FPH-MTVFENVAFGlrmqKTPAAEITPR--------VMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVN 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 157 DAAIVLLDEPTTYLDI----SHQVELLDLMRELsaeGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK09452 162 KPKVLLLDESLSALDYklrkQMQNELKALQRKL---GITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREI 232

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

13-228

3.31e-22

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 95.58 E-value: 3.31e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLK--AFARILtpQSGSLSLDGKGYSQLSARELAC-KVAFLPQVLpip 89
Cdd:NF033858  11 YGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSliAGARKI--QQGRVEVLGGDMADARHRRAVCpRIAYMPQGL--- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  90 eGVN------VRQLVAYgrsphnslWGRLSGADQHS----VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAA 159
Cdd:NF033858  86 -GKNlyptlsVFENLDF--------FGRLFGQDAAErrrrIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPD 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 160 IVLLDEPTTYLD-ISHQV--ELLDLMRElSAEGKTVITVLHDINQACRYaDHLAVMQGGRLVTCGAPGDVLT 228
Cdd:NF033858 157 LLILDEPTTGVDpLSRRQfwELIDRIRA-ERPGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAELLA 226

fbpC

PRK11432

ferric ABC transporter ATP-binding protein;

13-225

3.42e-22

ferric ABC transporter ATP-binding protein;

Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 93.63 E-value: 3.42e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLS--ARELaCKV----AFLPQvL 86
Cdd:PRK11432  16 FGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSiqQRDI-CMVfqsyALFPH-M 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  87 PIPEGvnvrqlVAYGRsphnSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:PRK11432  94 SLGEN------VGYGL----KMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEP 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 167 TTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGD 225
Cdd:PRK11432 164 LSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQE 223

nikE

PRK10419

nickel ABC transporter ATP-binding protein NikE;

1-228

5.02e-22

nickel ABC transporter ATP-binding protein NikE;

Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 92.06 E-value: 5.02e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGY---------GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLS 71
Cdd:PRK10419   1 MTLLNVSGLSHHYahgglsgkhQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  72 ARElacKVAFLPQVLPI----PEGVNVRQLV-AYGRSPHNSLWGrLSGADQ-HSVDQALQRMELA-TLAERPLSDLSGGQ 144
Cdd:PRK10419  81 RAQ---RKAFRRDIQMVfqdsISAVNPRKTVrEIIREPLRHLLS-LDKAERlARASEMLRAVDLDdSVLDKRPPQLSGGQ 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 145 RQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTV-ITVLHDINQACRYADHLAVMQGGRLVTCGAP 223
Cdd:PRK10419 157 LQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTAcLFITHDLRLVERFCQRVMVMDNGQIVETQPV 236


                 ....*
gi 492172462 224 GDVLT 228
Cdd:PRK10419 237 GDKLT 241

ABC_FtsE

cd03292

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...

21-198

1.04e-21

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages

Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 89.77 E-value: 1.04e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC---KVAFLPQVLPIPEGVNVRQL 97
Cdd:cd03292   19 GINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYlrrKIGVVFQDFRLLPDRNVYEN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  98 VAYGRsphnslwgRLSGAD----QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDIS 173
Cdd:cd03292   99 VAFAL--------EVTGVPpreiRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPD 170

                        170       180
                 ....*....|....*....|....*
gi 492172462 174 HQVELLDLMRELSAEGKTVITVLHD 198
Cdd:cd03292  171 TTWEIMNLLKKINKAGTTVVVATHA 195

PRK10895

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

1-236

1.07e-21

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 90.34 E-value: 1.07e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACK-V 79
Cdd:PRK10895   1 MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRgI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQvlpipEGVNVRQLVAYgrsphNSLWGRLS-----GADQHSvDQALQRME---LATLAERPLSDLSGGQRQRAWLA 151
Cdd:PRK10895  81 GYLPQ-----EASIFRRLSVY-----DNLMAVLQirddlSAEQRE-DRANELMEefhIEHLRDSMGQSLSGGERRRVEIA 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 152 MILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAEL 231
Cdd:PRK10895 150 RALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEH 229


                 ....*
gi 492172462 232 VCQVF 236
Cdd:PRK10895 230 VKRVY 234

nickel_nikE

TIGR02769

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...

18-218

1.09e-21

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 91.02 E-value: 1.09e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQL---SARELACKVAFLPQvlPIPEGVNV 94
Cdd:TIGR02769  26 VLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLdrkQRRAFRRDVQLVFQ--DSPSAVNP 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   95 RQLV-AYGRSPHNSLwGRLSGADQHSVDQALQRM-EL-ATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:TIGR02769 104 RMTVrQIIGEPLRHL-TSLDESEQKARIAELLDMvGLrSEDADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVSNLD 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 492172462  172 ISHQVELLDLMRELSAEGKTV-ITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:TIGR02769 183 MVLQAVILELLRKLQQAFGTAyLFITHDLRLVQSFCQRVAVMDKGQIV 230

MsbA_lipidA

TIGR02203

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...

4-229

1.10e-21

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]

Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 94.01 E-value: 1.10e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    4 LKAQHLDIGYGATRI--VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAF 81
Cdd:TIGR02203 331 VEFRNVTFRYPGRDRpaLDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLRRQVAL 410

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   82 LPQVLPIPEGvNVRQLVAYGRsphnslwgrLSGADQHSVDQALQRMELATLAER-PL----------SDLSGGQRQRAWL 150
Cdd:TIGR02203 411 VSQDVVLFND-TIANNIAYGR---------TEQADRAEIERALAAAYAQDFVDKlPLgldtpigengVLLSGGQRQRLAI 480

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462  151 AMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELsAEGKTVITVLHDINqACRYADHLAVMQGGRLVTCGAPGDVLTA 229
Cdd:TIGR02203 481 ARALLKDAPILILDEATSALDNESERLVQAALERL-MQGRTTLVIAHRLS-TIEKADRIVVMDDGRIVERGTHNELLAR 557

ABCC_MRP_domain1

cd03250

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...

18-216

1.78e-21

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 89.07 E-value: 1.78e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelackVAFLPQVLPIPEGvNVRQL 97
Cdd:cd03250   20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS-------------IAYVSQEPWIQNG-TIREN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  98 VAYGrSPHNSLWGRlsgadqhSV------DQALQRME---LATLAERPLSdLSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:cd03250   86 ILFG-KPFDEERYE-------KVikacalEPDLEILPdgdLTEIGEKGIN-LSGGQKQRISLARAVYSDADIYLLDDPLS 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 492172462 169 YLDiSHQVELL--DLMRELSAEGKTVITVLHDInQACRYADHLAVMQGGR 216
Cdd:cd03250  157 AVD-AHVGRHIfeNCILGLLLNNKTRILVTHQL-QLLPHADQIVVLDNGR 204

ccmA

TIGR01189

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...

4-197

2.51e-21

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]

Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 88.57 E-value: 2.51e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLsARELACKVAFLP 83
Cdd:TIGR01189   1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQ-RDEPHENILYLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   84 QVLPIPEGVNVRQLVaygrsphnSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:TIGR01189  80 HLPGLKPELSALENL--------HFWAAIHGGAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWIL 151

                         170       180       190
                  ....*....|....*....|....*....|....
gi 492172462  164 DEPTTYLDISHQVELLDLMRELSAEGKTVITVLH 197
Cdd:TIGR01189 152 DEPTTALDKAGVALLAGLLRAHLARGGIVLLTTH 185

PRK10619

histidine ABC transporter ATP-binding protein HisP;

13-227

2.94e-21

histidine ABC transporter ATP-binding protein HisP;

Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 89.64 E-value: 2.94e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVlpipEGV 92
Cdd:PRK10619  15 YGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLKVADKNQL----RLL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQLVAYgrsPHNSLWGRLSG--------------ADQHSVDQALQRMELATLAERPL----SDLSGGQRQRAWLAMIL 154
Cdd:PRK10619  91 RTRLTMVF---QHFNLWSHMTVlenvmeapiqvlglSKQEARERAVKYLAKVGIDERAQgkypVHLSGGQQQRVSIARAL 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462 155 AQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:PRK10619 168 AMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLF 240

nikD

PRK10418

nickel transporter ATP-binding protein NikD; Provisional

18-229

7.04e-21

nickel transporter ATP-binding protein NikD; Provisional

Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 88.60 E-value: 7.04e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTP----QSGSLSLDGKGY--SQLSARELAC-----KVAFLPqvl 86
Cdd:PRK10418  18 LVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAgvrqTAGRVLLDGKPVapCALRGRKIATimqnpRSAFNP--- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  87 pipegvnVRQLVAYGRSPHNSLwGRLSgadqhSVDQALQRMELATLAE--RPLS----DLSGGQRQRAWLAMILAQDAAI 160
Cdd:PRK10418  95 -------LHTMHTHARETCLAL-GKPA-----DDATLTAALEAVGLENaaRVLKlypfEMSGGMLQRMMIALALLCEAPF 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 161 VLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTA 229
Cdd:PRK10418 162 IIADEPTTDLDVVAQARILDLLESIVQKrALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNA 231

PRK13633

energy-coupling factor transporter ATPase;

19-226

1.08e-20

energy-coupling factor transporter ATPase;

Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 88.61 E-value: 1.08e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYS---------------------QLSARELAC 77
Cdd:PRK13633  26 LDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSdeenlwdirnkagmvfqnpdnQIVATIVEE 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 KVAFLPQVLPI-PEGVNVRqlvaygrsphnslwgrlsgadqhsVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQ 156
Cdd:PRK13633 106 DVAFGPENLGIpPEEIRER------------------------VDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAM 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 157 DAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK13633 162 RPECIIFDEPTAMLDPSGRREVVNTIKELNKKyGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEI 231

ABC_Carb_Monos_II

cd03215

Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...

3-217

1.36e-20

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 85.95 E-value: 1.36e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGatriVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LACKVAF 81
Cdd:cd03215    4 VLEVRGLSVKGA----VRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDaIRAGIAY 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LP---------QVLPIPEGVNVRQLvaygrsphnslwgrlsgadqhsvdqalqrmelatlaerplsdLSGGQRQRAWLAM 152
Cdd:cd03215   80 VPedrkreglvLDLSVAENIALSSL------------------------------------------LSGGNQQKVVLAR 117

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 153 ILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:cd03215  118 WLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182

ABCC_Hemolysin

cd03252

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...

7-230

1.39e-20

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.

Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 87.54 E-value: 1.39e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   7 QHLDIGYGATR--IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSqlsareLACKVAFLPQ 84
Cdd:cd03252    4 EHVRFRYKPDGpvILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLA------LADPAWLRRQ 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 VlpipeGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQR-------MEL-----ATLAERPLSdLSGGQRQRAWLAM 152
Cdd:cd03252   78 V-----GVVLQENVLFNRSIRDNIALADPGMSMERVIEAAKLagahdfiSELpegydTIVGEQGAG-LSGGQRQRIAIAR 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 153 ILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAeGKTVITVLHDINqACRYADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:cd03252  152 ALIHNPRILIFDEATSALDYESEHAIMRNMHDICA-GRTVIIIAHRLS-TVKNADRIIVMEKGRIVEQGSHDELLAEN 227

AbcC

COG1135

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

14-228

1.42e-20

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 88.98 E-value: 1.42e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC---KVAFlpqvlpIPE 90
Cdd:COG1135   16 GPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAarrKIGM------IFQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 GVN------VRQLVAYgrsphnSLwgRLSGAD----QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAI 160
Cdd:COG1135   90 HFNllssrtVAENVAL------PL--EIAGVPkaeiRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKV 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 161 VLLDEPTTYLD--ISHQVelLDLMRELSAE-GKTVITVLHD---INQACryaDHLAVMQGGRLVTCGAPGDVLT 228
Cdd:COG1135  162 LLCDEATSALDpeTTRSI--LDLLKDINRElGLTIVLITHEmdvVRRIC---DRVAVLENGRIVEQGPVLDVFA 230

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

3-218

1.65e-20

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 90.08 E-value: 1.65e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLdigyGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LACKVAF 81
Cdd:COG1129  256 VLEVEGL----SVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDaIRAGIAY 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LP---------QVLPIPEGVNVRQLVAYGRsphnslWGRLSGADQHS-VDQALQRMELATL-AERPLSDLSGGQRQRAWL 150
Cdd:COG1129  332 VPedrkgeglvLDLSIRENITLASLDRLSR------GGLLDRRRERAlAEEYIKRLRIKTPsPEQPVGNLSGGNQQKVVL 405

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 151 AMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:COG1129  406 AKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAEGKAVIVISSELPELLGLSDRILVMREGRIV 473

cbiO

PRK13646

energy-coupling factor transporter ATPase;

19-226

1.69e-20

energy-coupling factor transporter ATPase;

Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 88.30 E-value: 1.69e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDG-KGYSQLSARELACKVAFLPQVLPIPEGV----N 93
Cdd:PRK13646  23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDiTITHKTKDKYIRPVRKRIGMVFQFPESQlfedT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 VRQLVAYGrsPHNSlwgrlsGADQHSV-DQALQR-MELA----TLAERPLSdLSGGQRQRAWLAMILAQDAAIVLLDEPT 167
Cdd:PRK13646 103 VEREIIFG--PKNF------KMNLDEVkNYAHRLlMDLGfsrdVMSQSPFQ-MSGGQMRKIAIVSILAMNPDIIVLDEPT 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 168 TYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK13646 174 AGLDPQSKRQVMRLLKSLQTDeNKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKEL 233

PRK11831

phospholipid ABC transporter ATP-binding protein MlaF;

14-223

2.13e-20

phospholipid ABC transporter ATP-binding protein MlaF;

Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 87.51 E-value: 2.13e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC---KVAFLPQVLPIPE 90
Cdd:PRK11831  18 GNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTvrkRMSMLFQSGALFT 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 GVNVRQLVAYGRSPHNslwgRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTY 169
Cdd:PRK11831  98 DMNVFDNVAYPLREHT----QLPAPLLHStVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVG 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 170 LD-ISHQVeLLDLMREL-SAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAP 223
Cdd:PRK11831 174 QDpITMGV-LVKLISELnSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSA 228

PRK11174

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

4-221

3.51e-20

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 89.52 E-value: 3.51e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDI-GYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILtPQSGSLSLDGKGYSQLSARELACKVAFL 82
Cdd:PRK11174 350 IEAEDLEIlSPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIELRELDPESWRKHLSWV 428

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLPIPEGvNVRQLVAYGRSphnslwgrlsGADQHSVDQALQRMELATLAER-------PLSD----LSGGQRQRAWLA 151
Cdd:PRK11174 429 GQNPQLPHG-TLRDNVLLGNP----------DASDEQLQQALENAWVSEFLPLlpqgldtPIGDqaagLSVGQAQRLALA 497

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 152 MILAQDAAIVLLDEPTTYLDiSHQVELldLMRELS--AEGKTVITVLHDINQACRYaDHLAVMQGGRLVTCG 221
Cdd:PRK11174 498 RALLQPCQLLLLDEPTASLD-AHSEQL--VMQALNaaSRRQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQQG 565

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

14-218

5.89e-20

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 87.09 E-value: 5.89e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAckvAFLPQVLPI---PE 90
Cdd:COG4608   29 GVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGRELR---PLRRRMQMVfqdPY 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 G-VN----VRQLVAYGRSPHnslwGRLSGAD-QHSVDQALQRMEL-ATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:COG4608  106 AsLNprmtVGDIIAEPLRIH----GLASKAErRERVAELLELVGLrPEHADRYPHEFSGGQRQRIGIARALALNPKLIVC 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 164 DEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINqACRY-ADHLAVMQGGRLV 218
Cdd:COG4608  182 DEPVSALDVSIQAQVLNLLEDLQDElGLTYLFISHDLS-VVRHiSDRVAVMYLGKIV 237

type_I_sec_HlyB

TIGR01846

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ...

18-221

6.45e-20

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 273831 [Multi-domain] Cd Length: 694 Bit Score: 88.65 E-value: 6.45e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQvlpipEGV----N 93
Cdd:TIGR01846 472 VLSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVDGVDLAIADPAWLRRQMGVVLQ-----ENVlfsrS 546

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   94 VRQLVAYGRS----PHNSLWGRLSGAdqHSVDQALQRMELATLAERPlSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTY 169
Cdd:TIGR01846 547 IRDNIALCNPgapfEHVIHAAKLAGA--HDFISELPQGYNTEVGEKG-ANLSGGQRQRIAIARALVGNPRILIFDEATSA 623

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 492172462  170 LDISHQVELLDLMRELSAeGKTVITVLHDINqACRYADHLAVMQGGRLVTCG 221
Cdd:TIGR01846 624 LDYESEALIMRNMREICR-GRTVIIIAHRLS-TVRACDRIIVLEKGQIAESG 673

cbiO

PRK13650

energy-coupling factor transporter ATPase;

18-223

7.88e-20

energy-coupling factor transporter ATPase;

Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 86.32 E-value: 7.88e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFlpqVLPIPE----GVN 93
Cdd:PRK13650  22 TLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIRHKIGM---VFQNPDnqfvGAT 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 VRQLVAYGRS----PHNSLWGRlsgadqhsVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTY 169
Cdd:PRK13650  99 VEDDVAFGLEnkgiPHEEMKER--------VNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSM 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 170 LDISHQVELLDLMRELSAE-GKTVITVLHDINQACrYADHLAVMQGGRLVTCGAP 223
Cdd:PRK13650 171 LDPEGRLELIKTIKGIRDDyQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTP 224

PRK09984

phosphonate ABC transporter ATP-binding protein;

2-222

1.07e-19

phosphonate ABC transporter ATP-binding protein;

Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 85.45 E-value: 1.07e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLS--------LDGKGYSQLSAR 73
Cdd:PRK09984   3 TIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGShiellgrtVQREGRLARDIR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  74 ELACKVAFLPQVLPIPEGVNVRQLVAYGRSPHNSLWGR----LSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAW 149
Cdd:PRK09984  83 KSRANTGYIFQQFNLVNRLSVLENVLIGALGSTPFWRTcfswFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVA 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 150 LAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSA-EGKTVITVLHDINQACRYADHLAVMQGGRLVTCGA 222
Cdd:PRK09984 163 IARALMQQAKVILADEPIASLDPESARIVMDTLRDINQnDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGS 236

YddA

COG4178

ABC-type uncharacterized transport system, permease and ATPase components [General function ...

16-197

1.95e-19

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];

Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 87.17 E-value: 1.95e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  16 TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGysqlsarelacKVAFLPQVLPIPEGvNVR 95
Cdd:COG4178  376 RPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARPAGA-----------RVLFLPQRPYLPLG-TLR 443

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  96 QLVAYgrsPHnslwgrlsGADQHS---VDQALQRMELATLAERpLSD-------LSGGQRQRAWLAMILAQDAAIVLLDE 165
Cdd:COG4178  444 EALLY---PA--------TAEAFSdaeLREALEAVGLGHLAER-LDEeadwdqvLSLGEQQRLAFARLLLHKPDWLFLDE 511

                        170       180       190
                 ....*....|....*....|....*....|..
gi 492172462 166 PTTYLDISHQVELLDLMRELSAEGkTVITVLH 197
Cdd:COG4178  512 ATSALDEENEAALYQLLREELPGT-TVISVGH 542

cbiO

PRK13631

cobalt transporter ATP-binding subunit; Provisional

3-230

1.97e-19

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 85.67 E-value: 1.97e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGAT-----RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLdGKGYSQLSARELAC 77
Cdd:PRK13631  21 ILRVKNLYCVFDEKqenelVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQV-GDIYIGDKKNNHEL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 KVAFLPQvlPIPEGVNVRQLVAY-GRSPHNSLWGRLSGAD---------QHSVDQA------LQRMEL-ATLAERPLSDL 140
Cdd:PRK13631 100 ITNPYSK--KIKNFKELRRRVSMvFQFPEYQLFKDTIEKDimfgpvalgVKKSEAKklakfyLNKMGLdDSYLERSPFGL 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 141 SGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTC 220
Cdd:PRK13631 178 SGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKT 257

                        250
                 ....*....|
gi 492172462 221 GAPGDVLTAE 230
Cdd:PRK13631 258 GTPYEIFTDQ 267

ssuB

PRK11247

aliphatic sulfonates transport ATP-binding subunit; Provisional

13-248

1.98e-19

aliphatic sulfonates transport ATP-binding subunit; Provisional

Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 84.73 E-value: 1.98e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSldgKGYSQLS-ARE---LACKVAFLpqvLPI 88
Cdd:PRK11247  22 YGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELL---AGTAPLAeAREdtrLMFQDARL---LPW 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  89 PEgvnVRQLVAYGrsphnslwgrLSGadqHSVDQALQRMELATLAER----PLSdLSGGQRQRAWLAMILAQDAAIVLLD 164
Cdd:PRK11247  96 KK---VIDNVGLG----------LKG---QWRDAALQALAAVGLADRanewPAA-LSGGQKQRVALARALIHRPGLLLLD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 165 EPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRL---VTCGAP-----GDVLTAELVCQV 235
Cdd:PRK11247 159 EPLGALDALTRIEMQDLIESLWQQhGFTVLLVTHDVSEAVAMADRVLLIEEGKIgldLTVDLPrprrrGSARLAELEAEV 238

                        250
                 ....*....|...
gi 492172462 236 FDvhvQIMREPVA 248
Cdd:PRK11247 239 LQ---RVMSRGES 248

cbiO

PRK13642

energy-coupling factor transporter ATPase;

3-235

2.38e-19

energy-coupling factor transporter ATPase;

Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 84.76 E-value: 2.38e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDL---SFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKV 79
Cdd:PRK13642   4 ILEVENLVFKYEKESDVNQLngvSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRRKI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFlpqVLPIPE----GVNVRQLVAYGRS----PHNSLWGRlsgadqhsVDQALQRMELATLAERPLSDLSGGQRQRAWLA 151
Cdd:PRK13642  84 GM---VFQNPDnqfvGATVEDDVAFGMEnqgiPREEMIKR--------VDEALLAVNMLDFKTREPARLSGGQKQRVAVA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 152 MILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGK-TVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDVL-TA 229
Cdd:PRK13642 153 GIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQlTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFaTS 231


                 ....*.
gi 492172462 230 ELVCQV 235
Cdd:PRK13642 232 EDMVEI 237

znuC

PRK09544

high-affinity zinc transporter ATPase; Reviewed

1-199

3.87e-19

high-affinity zinc transporter ATPase; Reviewed

Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 83.62 E-value: 3.87e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKA-QHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSldgkgysqlsaRELACKV 79
Cdd:PRK09544   1 MTSLVSlENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK-----------RNGKLRI 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQVL----PIPEGVnvrqlvaygrsphnSLWGRLS-GADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMIL 154
Cdd:PRK09544  70 GYVPQKLyldtTLPLTV--------------NRFLRLRpGTKKEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARAL 135

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 492172462 155 AQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDI 199
Cdd:PRK09544 136 LNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRElDCAVLMVSHDL 181

ATM1

COG5265

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...

7-221

3.94e-19

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 86.41 E-value: 3.94e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   7 QHLDIGYGATR-IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDG---KGYSQLSARElacKVAFL 82
Cdd:COG5265  361 ENVSFGYDPERpILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGqdiRDVTQASLRA---AIGIV 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQ--VLpipegVN--VRQLVAYGRSphnslwgrlsGADQHSVDQALQRMEL-----------ATL-AERPLSdLSGGQRQ 146
Cdd:COG5265  438 PQdtVL-----FNdtIAYNIAYGRP----------DASEEEVEAAARAAQIhdfieslpdgyDTRvGERGLK-LSGGEKQ 501

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 147 RAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSaEGKTVITVLHdinqacR-----YADHLAVMQGGRLVTCG 221
Cdd:COG5265  502 RVAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVA-RGRTTLVIAH------RlstivDADEILVLEAGRIVERG 574

PRK14271

phosphate ABC transporter ATP-binding protein; Provisional

4-221

4.17e-19

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 84.38 E-value: 4.17e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTP-----QSGSLSLDGKG-YSQLSARELAC 77
Cdd:PRK14271  22 MAAVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKvsgyrYSGDVLLGGRSiFNYRDVLEFRR 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 KVAFLPQvLPIPEGVNVRQLVAYGRSPHNslwgRLSGADQHSVDQA-LQRMELATLAERPLSD----LSGGQRQRAWLAM 152
Cdd:PRK14271 102 RVGMLFQ-RPNPFPMSIMDNVLAGVRAHK----LVPRKEFRGVAQArLTEVGLWDAVKDRLSDspfrLSGGQQQLLCLAR 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 153 ILAQDAAIVLLDEPTTYLDISHQVELLDLMRELsAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:PRK14271 177 TLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSL-ADRLTVIIVTHNLAQAARISDRAALFFDGRLVEEG 244

PhnK

COG1101

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

17-218

4.55e-19

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 83.60 E-value: 4.55e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAckvAFLPQV----------- 85
Cdd:COG1101   20 RALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRA---KYIGRVfqdpmmgtaps 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  86 LPIPEgvNVrqLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELAtLAER---PLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:COG1101   97 MTIEE--NL--ALAYRRGKRRGLRRGLTKKRRELFRELLATLGLG-LENRldtKVGLLSGGQRQALSLLMATLTKPKLLL 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 163 LDEPTTYLD--ISHQVelLDLMRELSAEGK-TVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:COG1101  172 LDEHTAALDpkTAALV--LELTEKIVEENNlTTLMVTHNMEQALDYGNRLIMMHEGRII 228

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

3-232

4.70e-19

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 85.87 E-value: 4.70e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLS---ARELAckV 79
Cdd:PRK15439  11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTpakAHQLG--I 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQVLPIPEGVNVRQLVAYGRSPHNslwgrlsgADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAA 159
Cdd:PRK15439  89 YLVPQEPLLFPNLSVKENILFGLPKRQ--------ASMQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSR 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462 160 IVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELV 232
Cdd:PRK15439 161 ILILDEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADLSTDDII 233

ABC_CcmA_heme_exporter

cd03231

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...

4-197

7.48e-19

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.

Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 81.77 E-value: 7.48e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSArELACKVAFLP 83
Cdd:cd03231    1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRD-SIARGLLYLG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVLPIPEGVNVRQLVAYgrsphnslWGRLSGADQhsVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:cd03231   80 HAPGIKTTLSVLENLRF--------WHADHSDEQ--VEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWIL 149

                        170       180       190
                 ....*....|....*....|....*....|....
gi 492172462 164 DEPTTYLDISHQVELLDLMRELSAEGKTVITVLH 197
Cdd:cd03231  150 DEPTTALDKAGVARFAEAMAGHCARGGMVVLTTH 183

ugpC

PRK11650

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

14-226

1.68e-18

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 83.35 E-value: 1.68e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLpIPEgVN 93
Cdd:PRK11650  15 GKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPADRDIAMVFQNYAL-YPH-MS 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 VRQLVAYGRsphnslwgRLSGADQHSVDQ----ALQRMELATLAERPLSDLSGGQRQRawLAMILA--QDAAIVLLDEPT 167
Cdd:PRK11650  93 VRENMAYGL--------KIRGMPKAEIEErvaeAARILELEPLLDRKPRELSGGQRQR--VAMGRAivREPAVFLFDEPL 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462 168 TYLD----ISHQVELLDLMRELSAegkTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK11650 163 SNLDaklrVQMRLEIQRLHRRLKT---TSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEV 222

dppF

PRK11308

dipeptide transporter ATP-binding subunit; Provisional

13-221

1.92e-18

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 83.09 E-value: 1.92e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDL---SFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK---GYSQLSARELACKVaflpqvl 86
Cdd:PRK11308  22 FKPERLVKALdgvSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQdllKADPEAQKLLRQKI------- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  87 pipegvnvrQLVAygRSPHNSLWGR----------------LSGADQhsVDQALQRMELATL----AERPLSDLSGGQRQ 146
Cdd:PRK11308  95 ---------QIVF--QNPYGSLNPRkkvgqileepllintsLSAAER--REKALAMMAKVGLrpehYDRYPHMFSGGQRQ 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 147 RAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:PRK11308 162 RIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQElGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKG 237

COG4586

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

19-200

1.99e-18

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 82.83 E-value: 1.99e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelackvaflpqvlpIP---EGVNVR 95
Cdd:COG4586   38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGY----------------------VPfkrRKEFAR 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  96 QL-VAYG-RSphnSLWGRLSGAD----------------QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQD 157
Cdd:COG4586   96 RIgVVFGqRS---QLWWDLPAIDsfrllkaiyripdaeyKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHR 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 492172462 158 AAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTviTVL---HDIN 200
Cdd:COG4586  173 PKILFLDEPTIGLDVVSKEAIREFLKEYNRERGT--TILltsHDMD 216

HisP

COG4598

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];

13-229

2.53e-18

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 81.77 E-value: 2.53e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  13 YGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAflpqvlpipegv 92
Cdd:COG4598   18 FGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKPDRDGELVPA------------ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQLVAYgRS------PHNSLWGRLS------GADQH----SVDQALQRMElATLAERPLSD--------LSGGQRQRA 148
Cdd:COG4598   86 DRRQLQRI-RTrlgmvfQSFNLWSHMTvlenviEAPVHvlgrPKAEAIERAE-ALLAKVGLADkrdaypahLSGGQQQRA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 149 WLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:COG4598  164 AIARALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEEGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFG 243


                 .
gi 492172462 229 A 229
Cdd:COG4598  244 N 244

PRK13651

cobalt transporter ATP-binding subunit; Provisional

21-227

3.52e-18

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 82.06 E-value: 3.52e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSL---DGKGYSQLSARELAC--------KVAFLPQVLPIP 89
Cdd:PRK13651  25 NVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWifkDEKNKKKTKEKEKVLeklviqktRFKKIKKIKEIR 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  90 EGVNV------RQL-------------VAYGRSPhnslwgrlsgadQHSVDQALQRMELATLAERPLS----DLSGGQRQ 146
Cdd:PRK13651 105 RRVGVvfqfaeYQLfeqtiekdiifgpVSMGVSK------------EEAKKRAAKYIELVGLDESYLQrspfELSGGQKR 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 147 RAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK13651 173 RVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTYDI 252


                 .
gi 492172462 227 L 227
Cdd:PRK13651 253 L 253

NHLM_micro_ABC1

TIGR03796

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...

10-218

3.71e-18

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]

Pssm-ID: 274788 [Multi-domain] Cd Length: 710 Bit Score: 83.45 E-value: 3.71e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   10 DIGYGATRI----VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQV 85
Cdd:TIGR03796 482 NITFGYSPLepplIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDGIPREEIPREVLANSVAMVDQD 561

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   86 LPIPEGvNVRQLVaygrsphnSLWGR------LSGADQ----HSVDQALQRMELATLAERPlSDLSGGQRQRAWLAMILA 155
Cdd:TIGR03796 562 IFLFEG-TVRDNL--------TLWDPtipdadLVRACKdaaiHDVITSRPGGYDAELAEGG-ANLSGGQRQRLEIARALV 631

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462  156 QDAAIVLLDEPTTYLDIshQVELLdLMRELSAEGKTVITVLHDINqACRYADHLAVMQGGRLV 218
Cdd:TIGR03796 632 RNPSILILDEATSALDP--ETEKI-IDDNLRRRGCTCIIVAHRLS-TIRDCDEIIVLERGKVV 690

metN

PRK11153

DL-methionine transporter ATP-binding subunit; Provisional

19-240

3.83e-18

DL-methionine transporter ATP-binding subunit; Provisional

Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 82.54 E-value: 3.83e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAckvAFLPQVLPIPEGVN----- 93
Cdd:PRK11153  21 LNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELR---KARRQIGMIFQHFNllssr 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 -VRQLVAygrsphnsLWGRLSGADQHS----VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:PRK11153  98 tVFDNVA--------LPLELAGTPKAEikarVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLCDEATS 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 169 YLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDV-------LTAELVCQVFDVHV 240
Cdd:PRK11153 170 ALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVfshpkhpLTREFIQSTLHLDL 249

PRK14258

phosphate ABC transporter ATP-binding protein; Provisional

4-228

4.10e-18

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 81.24 E-value: 4.10e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARiLTPQSGSLSLDGK----GYS----QLSAREL 75
Cdd:PRK14258   8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNR-MNELESEVRVEGRveffNQNiyerRVNLNRL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  76 ACKVAFL---PQVLPIpegvNVRQLVAYGRS-----PHNSLWGRLSGA--DQHSVDQALQRMELATLaerplsDLSGGQR 145
Cdd:PRK14258  87 RRQVSMVhpkPNLFPM----SVYDNVAYGVKivgwrPKLEIDDIVESAlkDADLWDEIKHKIHKSAL------DLSGGQQ 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 146 QRAWLAMILAQDAAIVLLDEPTTYLD------ISHQVELLDLMRELsaegkTVITVLHDINQACRYADHLAVMQG----- 214
Cdd:PRK14258 157 QRLCIARALAVKPKVLLMDEPCFGLDpiasmkVESLIQSLRLRSEL-----TMVIVSHNLHQVSRLSDFTAFFKGnenri 231

                        250
                 ....*....|....
gi 492172462 215 GRLVTCGAPGDVLT 228
Cdd:PRK14258 232 GQLVEFGLTKKIFN 245

NHLM_micro_ABC2

TIGR03797

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...

4-230

5.01e-18

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]

Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 83.08 E-value: 5.01e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    4 LKAQHLDIGYG--ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLkafaRIL----TPQSGSLSLDGKGYSQLSARELAc 77
Cdd:TIGR03797 452 IEVDRVTFRYRpdGPLILDDVSLQIEPGEFVAIVGPSGSGKSTLL----RLLlgfeTPESGSVFYDGQDLAGLDVQAVR- 526

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   78 kvaflpqvlpipegvnvRQL---VAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLAE----RPL----------SDL 140
Cdd:TIGR03797 527 -----------------RQLgvvLQNGRLMSGSIFENIAGGAPLTLDEAWEAARMAGLAEdiraMPMgmhtviseggGTL 589

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  141 SGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAegkTVITVLHDINqACRYADHLAVMQGGRLVTC 220
Cdd:TIGR03797 590 SGGQRQRLLIARALVRKPRILLFDEATSALDNRTQAIVSESLERLKV---TRIVIAHRLS-TIRNADRIYVLDAGRVVQQ 665

                         250
                  ....*....|
gi 492172462  221 GAPGDVLTAE 230
Cdd:TIGR03797 666 GTYDELMARE 675

cbiO

PRK13644

energy-coupling factor transporter ATPase;

29-228

5.07e-18

energy-coupling factor transporter ATPase;

Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 81.19 E-value: 5.07e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSL---SLDGKGYSQLSA-RELACKVAFLPQVLPIpeGVNVRQLVAYGrsP 104
Cdd:PRK13644  28 GEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVlvsGIDTGDFSKLQGiRKLVGIVFQNPETQFV--GRTVEEDLAFG--P 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 105 HNSLWGRLSgaDQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRE 184
Cdd:PRK13644 104 ENLCLPPIE--IRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVLERIKK 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 492172462 185 LSAEGKTVITVLHDINQaCRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:PRK13644 182 LHEKGKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLS 224

PhnL

COG4778

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...

14-216

6.07e-18

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];

Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 80.17 E-value: 6.07e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRI--VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKG----YSQLSARELackVA------- 80
Cdd:COG4778   20 GGKRLpvLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGgwvdLAQASPREI---LAlrrrtig 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 ----FLpQVLPipeGVNVRQLVAygrsphNSLwgRLSGADQhsvDQALQRME--LATL--AERpLSDL-----SGGQRQR 147
Cdd:COG4778   97 yvsqFL-RVIP---RVSALDVVA------EPL--LERGVDR---EEARARARelLARLnlPER-LWDLppatfSGGEQQR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 148 AWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGR 216
Cdd:COG4778  161 VNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEEVREAVADRVVDVTPFS 229

ntrCD

TIGR01184

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...

19-215

7.10e-18

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]

Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 79.82 E-value: 7.10e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELackVAFlpQVLPIPEGVNVRQLV 98
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRM---VVF--QNYSLLPWLTVRENI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   99 AYGRsphNSLWGRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVE 177
Cdd:TIGR01184  76 ALAV---DRVLPDLSKSERRAiVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGN 152

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 492172462  178 LLD-LMRELSAEGKTVITVLHDINQACRYADHLAVMQGG 215
Cdd:TIGR01184 153 LQEeLMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191

cbiO

PRK13645

energy-coupling factor transporter ATPase;

21-235

1.04e-17

energy-coupling factor transporter ATPase;

Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 80.44 E-value: 1.04e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSppAGQVTALIGPNGCGKSTLLKAFARILTPQSG-SLSLDGKGYSQL----SARELACKVAFlpqVLPIPE----G 91
Cdd:PRK13645  31 SLTFK--KNKVTCVIGTTGSGKSTMIQLTNGLIISETGqTIVGDYAIPANLkkikEVKRLRKEIGL---VFQFPEyqlfQ 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 VNVRQLVAYGrsPHNSlwgrlsGADQHSVDQAL-QRMELATL----AERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:PRK13645 106 ETIEKDIAFG--PVNL------GENKQEAYKKVpELLKLVQLpedyVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEP 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 167 TTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT-AELVCQV 235
Cdd:PRK13645 178 TGGLDPKGEEDFINLFERLNKEyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSnQELLTKI 248

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

1-218

2.12e-17

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 81.29 E-value: 2.12e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGY---GATR-IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARIL-TPQ----SGSLSLDGKGYSQLS 71
Cdd:PRK15134   3 QPLLAIENLSVAFrqqQTVRtVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLpSPPvvypSGDIRFHGESLLHAS 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  72 AREL----ACKVAF------------------LPQVLPIPEGVnvRQLVAYGRSphnslwgrLSGADQHSVDQALQRmel 129
Cdd:PRK15134  83 EQTLrgvrGNKIAMifqepmvslnplhtlekqLYEVLSLHRGM--RREAARGEI--------LNCLDRVGIRQAAKR--- 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 130 atLAERPlSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADH 208
Cdd:PRK15134 150 --LTDYP-HQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITHNLSIVRKLADR 226

                        250
                 ....*....|
gi 492172462 209 LAVMQGGRLV 218
Cdd:PRK15134 227 VAVMQNGRCV 236

lolD

PRK11629

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

16-217

2.86e-17

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 78.32 E-value: 2.86e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  16 TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC----KVAFLPQ---VLP- 87
Cdd:PRK11629  22 TDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAElrnqKLGFIYQfhhLLPd 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  88 --IPEGVNVRQLVAyGRSPHNSlwgrlsgadQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDE 165
Cdd:PRK11629 102 ftALENVAMPLLIG-KKKPAEI---------NSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADE 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 492172462 166 PTTYLDISHQVELLDLMRELSA-EGKTVITVLHDINQACRYADHLAvMQGGRL 217
Cdd:PRK11629 172 PTGNLDARNADSIFQLLGELNRlQGTAFLVVTHDLQLAKRMSRQLE-MRDGRL 223

ABCC_NFT1

cd03369

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...

4-223

3.33e-17

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 77.45 E-value: 3.33e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGA--TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAF 81
Cdd:cd03369    7 IEVENLSVRYAPdlPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQVLPIPEGVNVRQLVAYGRSPHNSLWGRLSGADQHsvdqalqrmelatlaerplSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:cd03369   87 IPQDPTLFSGTIRSNLDPFDEYSDEEIYGALRVSEGG-------------------LNLSQGQRQLLCLARALLKRPRVL 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 162 LLDEPTTYLDISHQVELLDLMRELSAeGKTVITVLHDINQACRYaDHLAVMQGGRLVTCGAP 223
Cdd:cd03369  148 VLDEATASIDYATDALIQKTIREEFT-NSTILTIAHRLRTIIDY-DKILVMDAGEVKEYDHP 207

LptB

COG1137

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...

1-236

3.49e-17

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 78.15 E-value: 3.49e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLS----AREla 76
Cdd:COG1137    1 MMTLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPmhkrARL-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  77 cKVAFLPQVLPIPEGVNVRQ---LVAYGRsphnslwgRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAM 152
Cdd:COG1137   79 -GIGYLPQEASIFRKLTVEDnilAVLELR--------KLSKKEREErLEELLEEFGITHLRKSKAYSLSGGERRRVEIAR 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 153 ILAQDAAIVLLDEPTTYLD-IShqV-ELLDLMRELSAEGktvITVL---HDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:COG1137  150 ALATNPKFILLDEPFAGVDpIA--VaDIQKIIRHLKERG---IGVLitdHNVRETLGICDRAYIISEGKVLAEGTPEEIL 224


                 ....*....
gi 492172462 228 TAELVCQVF 236
Cdd:COG1137  225 NNPLVRKVY 233

YbbA

COG4181

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...

2-219

3.52e-17

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 77.86 E-value: 3.52e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHL----DIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLS----AR 73
Cdd:COG4181    7 PIIELRGLtktvGTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDedarAR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  74 ELACKVAFLPQ--------------VLPIpEGVNVRQlvAYGRSphnslwgrlsgadqhsvDQALQRMELATLAE-RPlS 138
Cdd:COG4181   87 LRARHVGFVFQsfqllptltalenvMLPL-ELAGRRD--ARARA-----------------RALLERVGLGHRLDhYP-A 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 139 DLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD--ISHQVelLDLMRELSAE-GKTVITVLHDINQACRyADHLAVMQGG 215
Cdd:COG4181  146 QLSGGEQQRVALARAFATEPAILFADEPTGNLDaaTGEQI--IDLLFELNRErGTTLVLVTHDPALAAR-CDRVLRLRAG 222


                 ....
gi 492172462 216 RLVT 219
Cdd:COG4181  223 RLVE 226

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

3-172

4.73e-17

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 80.36 E-value: 4.73e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLdGKgysqlsarelACKVAFL 82
Cdd:TIGR03719 322 VIEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GE----------TVKLAYV 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   83 PQvlpipegvnvrqlvayGRS---PHNSLWGRLSGADQHSVdqaLQRMELATLA------------ERPLSDLSGGQRQR 147
Cdd:TIGR03719 391 DQ----------------SRDaldPNKTVWEEISGGLDIIK---LGKREIPSRAyvgrfnfkgsdqQKKVGQLSGGERNR 451

                         170       180
                  ....*....|....*....|....*
gi 492172462  148 AWLAMILAQDAAIVLLDEPTTYLDI 172
Cdd:TIGR03719 452 VHLAKTLKSGGNVLLLDEPTNDLDV 476

PvdE

COG4615

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...

21-218

5.47e-17

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];

Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 79.84 E-value: 5.47e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPpaGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysQLSARELAckvAFlpqvlpipegvnvRQLVA- 99
Cdd:COG4615  352 DLTIRR--GELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQ---PVTADNRE---AY-------------RQLFSa 410

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 100 ----YgrspH--NSLWGRLSGADQHSVDQALQRMELA---TLAERPLS--DLSGGQRQRawLAMILA--QDAAIVLLDE- 165
Cdd:COG4615  411 vfsdF----HlfDRLLGLDGEADPARARELLERLELDhkvSVEDGRFSttDLSQGQRKR--LALLVAllEDRPILVFDEw 484

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 166 -----PtTYLDISHQvELLDLMRelsAEGKTVITVLHDInqacRY---ADHLAVMQGGRLV 218
Cdd:COG4615  485 aadqdP-EFRRVFYT-ELLPELK---ARGKTVIAISHDD----RYfdlADRVLKMDYGKLV 536

PRK11264

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

21-221

5.49e-17

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 77.87 E-value: 5.49e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPpaGQVTALIGPNGCGKSTLLKAFARILTPQSGSL-----SLDGK---GYSQLSARELACKVAFLPQ---VLP-- 87
Cdd:PRK11264  23 DLEVKP--GEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgdiTIDTArslSQQKGLIRQLRQHVGFVFQnfnLFPhr 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  88 -----IPEG-VNVR-----QLVAYGRsphnslwgrlsgadqhsvdQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQ 156
Cdd:PRK11264 101 tvlenIIEGpVIVKgepkeEATARAR-------------------ELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAM 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 157 DAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:PRK11264 162 RPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQG 226

ABCC_MRP_domain2

cd03244

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...

18-223

6.38e-17

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 77.15 E-value: 6.38e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVlPIPEGVNVRQ- 96
Cdd:cd03244   19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSRISIIPQD-PVLFSGTIRSn 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  97 LVAYGRSPHNSLWgrlsgadqhsvdQALQRMELATLAERPL-----------SDLSGGQRQRAWLAMILAQDAAIVLLDE 165
Cdd:cd03244   98 LDPFGEYSDEELW------------QALERVGLKEFVESLPggldtvveeggENLSVGQRQLLCLARALLRKSKILVLDE 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 166 PTTYLDISHQVELLDLMRELSAeGKTVITVLHDINQACRYaDHLAVMQGGRLVTCGAP 223
Cdd:cd03244  166 ATASVDPETDALIQKTIREAFK-DCTVLTIAHRLDTIIDS-DRILVLDKGRVVEFDSP 221

livG

PRK11300

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

3-226

6.81e-17

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 77.72 E-value: 6.81e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKvafl 82
Cdd:PRK11300   5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARM---- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 pqvlpipeGV-----NVR----------QLVAYGRSPHNSLwgrLSG---------ADQHSVDQA---LQRMELATLAER 135
Cdd:PRK11300  81 --------GVvrtfqHVRlfremtvienLLVAQHQQLKTGL---FSGllktpafrrAESEALDRAatwLERVGLLEHANR 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 136 PLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQG 214
Cdd:PRK11300 150 QAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQ 229

                        250
                 ....*....|..
gi 492172462 215 GRLVTCGAPGDV 226
Cdd:PRK11300 230 GTPLANGTPEEI 241

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

19-230

7.97e-17

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 79.44 E-value: 7.97e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK---------------GYSQLSARElackVAFLP 83
Cdd:PRK09700 279 VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKdisprspldavkkgmAYITESRRD----NGFFP 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 QVlpipegvNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMELATLA------ERPLSDLSGGQRQRAWLAMILAQD 157
Cdd:PRK09700 355 NF-------SIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQRELLAlkchsvNQNITELSGGNQQKVLISKWLCCC 427

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462 158 AAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:PRK09700 428 PEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSEE 500

PRK10261

glutathione transporter ATP-binding protein; Provisional

19-221

1.19e-16

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 79.13 E-value: 1.19e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIP-EGVNVRQL 97
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRDIQFIFQDPyASLDPRQT 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  98 VAYGRSPHNSLWGRLSG-ADQHSVDQALQRMEL-ATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQ 175
Cdd:PRK10261 420 VGDSIMEPLRVHGLLPGkAAAARVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIR 499

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 492172462 176 VELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:PRK10261 500 GQIINLLLDLQRDfGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546

PRK13657

glucan ABC transporter ATP-binding protein/ permease;

14-221

1.54e-16

glucan ABC transporter ATP-binding protein/ permease;

Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 78.85 E-value: 1.54e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSAREL--ACKVAFLPQVLpipeg 91
Cdd:PRK13657 346 NSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLrrNIAVVFQDAGL----- 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 vnvrqlvaYGRSPHNSLW-GRLSGADQHSVD-----QALQRME-----LATLA-ERPLSdLSGGQRQRAWLAMILAQDAA 159
Cdd:PRK13657 421 --------FNRSIEDNIRvGRPDATDEEMRAaaeraQAHDFIErkpdgYDTVVgERGRQ-LSGGERQRLAIARALLKDPP 491

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 160 IVLLDEPTTYLDISHQVELLDLMRELSaEGKTVITVLHDINqACRYADHLAVMQGGRLVTCG 221
Cdd:PRK13657 492 ILILDEATSALDVETEAKVKAALDELM-KGRTTFIIAHRLS-TVRNADRILVFDNGRVVESG 551

SufC

COG0396

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...

17-218

3.32e-16

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 75.49 E-value: 3.32e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARI--LTPQSGSLSLDGKGYSQLSARELACK---VAFlPQVLPIPeG 91
Cdd:COG0396   14 EILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHpkYEVTSGSILLDGEDILELSPDERARAgifLAF-QYPVEIP-G 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 VNVRQLVaygRSPHNSLWG-RLSGADQHS-VDQALQRMEL-ATLAERPL-SDLSGGQRQRAWLAMILAQDAAIVLLDEPT 167
Cdd:COG0396   92 VSVSNFL---RTALNARRGeELSAREFLKlLKEKMKELGLdEDFLDRYVnEGFSGGEKKRNEILQMLLLEPKLAILDETD 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 168 TYLDI-SHQVeLLDLMRELSAEGKT--VIT----VLHDINqacryADHLAVMQGGRLV 218
Cdd:COG0396  169 SGLDIdALRI-VAEGVNKLRSPDRGilIIThyqrILDYIK-----PDFVHVLVDGRIV 220

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

30-223

3.96e-16

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 78.13 E-value: 3.96e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    30 QVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGY-SQLSArelackvaflpqvlpipegvnVRQlvAYGRSP-HNS 107
Cdd:TIGR01257  957 QITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIeTNLDA---------------------VRQ--SLGMCPqHNI 1013

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   108 LWGRLSGADQ---------HSVDQALQRMElATLAERPL--------SDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYL 170
Cdd:TIGR01257 1014 LFHHLTVAEHilfyaqlkgRSWEEAQLEME-AMLEDTGLhhkrneeaQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGV 1092

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 492172462   171 DISHQVELLDLMRELSAeGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAP 223
Cdd:TIGR01257 1093 DPYSRRSIWDLLLKYRS-GRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144

PRK10535

macrolide ABC transporter ATP-binding protein/permease MacB;

12-198

8.53e-16

macrolide ABC transporter ATP-binding protein/permease MacB;

Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 76.69 E-value: 8.53e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELAC----KVAFLPQ--- 84
Cdd:PRK10535  17 GEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQlrreHFGFIFQryh 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 VLP-IPEGVNVRQLVAYGRSPHNSlwgRLSGADQhsvdqALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:PRK10535  97 LLShLTAAQNVEVPAVYAGLERKQ---RLLRAQE-----LLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILA 168

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 492172462 164 DEPTTYLDISHQVELLDLMRELSAEGKTVITVLHD 198
Cdd:PRK10535 169 DEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHD 203

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

4-227

1.85e-15

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 75.61 E-value: 1.85e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLD-GKGYSQLSARELACK---- 78
Cdd:TIGR03269 285 VSKRYISVDRGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvGDEWVDMTKPGPDGRgrak 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   79 --VAFLPQvlpipegvnvrqlvAYGRSPHNSLWGRLSGA------DQHSVDQALQRMELATLAE--------RPLSDLSG 142
Cdd:TIGR03269 365 ryIGILHQ--------------EYDLYPHRTVLDNLTEAiglelpDELARMKAVITLKMVGFDEekaeeildKYPDELSE 430

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  143 GQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLD-LMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:TIGR03269 431 GERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHsILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIG 510


                  ....*.
gi 492172462  222 APGDVL 227
Cdd:TIGR03269 511 DPEEIV 516

sufC

TIGR01978

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...

4-223

2.90e-15

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]

Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 73.06 E-value: 2.90e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFA-----RIltpQSGSLSLDGKGYSQLSARELACK 78
Cdd:TIGR01978   1 LKIKDLHVSVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAghpsyEV---TSGTILFKGQDLLELEPDERARA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   79 VAFLPQVLP--IPeGVNVRQLVaygRSPHNSlwgRLSGADQHSVD---------QALQRMEL-ATLAERPLSD-LSGGQR 145
Cdd:TIGR01978  78 GLFLAFQYPeeIP-GVSNLEFL---RSALNA---RRSARGEEPLDlldfekllkEKLALLDMdEEFLNRSVNEgFSGGEK 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  146 QRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDiNQACRY--ADHLAVMQGGRLVTCGAP 223
Cdd:TIGR01978 151 KRNEILQMALLEPKLAILDEIDSGLDIDALKIVAEGINRLREPDRSFLIITHY-QRLLNYikPDYVHVLLDGRIVKSGDV 229

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

3-217

3.20e-15

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 74.86 E-value: 3.20e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    3 ILKAQHL---DIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKA-FARILTPQSGSLSLDGKGYSQLS-ARELAC 77
Cdd:TIGR02633 257 ILEARNLtcwDVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQAlFGAYPGKFEGNVFINGKPVDIRNpAQAIRA 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   78 KVAFLPQ---------VLPIPEGVNVRQLVAYgrsphnSLWGRL-SGADQHSVDQALQRMELATLA-ERPLSDLSGGQRQ 146
Cdd:TIGR02633 337 GIAMVPEdrkrhgivpILGVGKNITLSVLKSF------CFKMRIdAAAELQIIGSAIQRLKVKTASpFLPIGRLSGGNQQ 410

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462  147 RAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:TIGR02633 411 KAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKL 481

PRK11147

ABC transporter ATPase component; Reviewed

18-198

3.51e-15

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 74.99 E-value: 3.51e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelaCKVAFLPQVLPI--PEGvNVR 95
Cdd:PRK11147 334 LVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTK-----------LEVAYFDQHRAEldPEK-TVM 401

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  96 QLVAYGRSPHNslwgrLSGADQHsVDQALQ-------RmelatlAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:PRK11147 402 DNLAEGKQEVM-----VNGRPRH-VLGYLQdflfhpkR------AMTPVKALSGGERNRLLLARLFLKPSNLLILDEPTN 469

                        170       180       190
                 ....*....|....*....|....*....|.
gi 492172462 169 YLDIshqvELLDLMRELSAEGK-TVITVLHD 198
Cdd:PRK11147 470 DLDV----ETLELLEELLDSYQgTVLLVSHD 496

ABCD_peroxisomal_ALDP

cd03223

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...

16-197

3.74e-15

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).

Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 71.03 E-value: 3.74e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  16 TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelaCKVAFLPQVLPIPEGvNVR 95
Cdd:cd03223   14 RVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEG-----------EDLLFLPQRPYLPLG-TLR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  96 QLVAYgrsPhnslWGRLsgadqhsvdqalqrmelatlaerplsdLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQ 175
Cdd:cd03223   82 EQLIY---P----WDDV---------------------------LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESE 127

                        170       180
                 ....*....|....*....|..
gi 492172462 176 VELLDLMRELSAegkTVITVLH 197
Cdd:cd03223  128 DRLYQLLKELGI---TVISVGH 146

3a01204

TIGR00955

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...

29-224

6.99e-15

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 73.93 E-value: 6.99e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   29 GQVTALIGPNGCGKSTLLKAFARILTP---QSGSLSLDGKgysQLSARELACKVAFLPQV-LPIP-----EGVNVRQLVA 99
Cdd:TIGR00955  51 GELLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGM---PIDAKEMRAISAYVQQDdLFIPtltvrEHLMFQAHLR 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  100 YGRSPHNSlwGRlsgadQHSVDQALQRMELATLA------ERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD-- 171
Cdd:TIGR00955 128 MPRRVTKK--EK-----RERVDEVLQALGLRKCAntrigvPGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLDsf 200

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 492172462  172 ISHQVelLDLMRELSAEGKTVITVLHD-INQACRYADHLAVMQGGRLVTCGAPG 224
Cdd:TIGR00955 201 MAYSV--VQVLKGLAQKGKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSPD 252

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

3-172

1.04e-14

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 73.23 E-value: 1.04e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSL-------------------- 62
Cdd:PRK11819 324 VIEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIgetvklayvdqsrdaldpnk 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  63 -------DGKGYSQLSARElackvaflpqvlpipegVNVRqlvAY-GRspHNslwgrLSGADQhsvdqalqrmelatlaE 134
Cdd:PRK11819 404 tvweeisGGLDIIKVGNRE-----------------IPSR---AYvGR--FN-----FKGGDQ----------------Q 440

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 492172462 135 RPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDI 172
Cdd:PRK11819 441 KKVGVLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDV 478

ABC_RNaseL_inhibitor

cd03222

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...

29-214

1.10e-14

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 69.91 E-value: 1.10e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGkgysqlsarelaCKVAFLPQVLpipegvnvrqlvaygrsphnsl 108
Cdd:cd03222   25 GEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDG------------ITPVYKPQYI---------------------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 109 wgrlsgadqhsvdqalqrmelatlaerplsDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE 188
Cdd:cd03222   71 ------------------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEE 120

                        170       180
                 ....*....|....*....|....*..
gi 492172462 189 G-KTVITVLHDINQACRYADHLAVMQG 214
Cdd:cd03222  121 GkKTALVVEHDLAVLDYLSDRIHVFEG 147

ABC_FeS_Assembly

cd03217

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...

4-221

1.18e-14

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.

Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 70.63 E-value: 1.18e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFA--RILTPQSGSLSLDGKGYSQLSARELACKVAF 81
Cdd:cd03217    1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMghPKYEVTEGEILFKGEDITDLPPEERARLGIF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 L-PQVLPIPEGVNVRQLVaygrsphnslwgrlsgadqhsvdqalqrmelatlaeRPLSD-LSGGQRQRAWLAMILAQDAA 159
Cdd:cd03217   81 LaFQYPPEIPGVKNADFL------------------------------------RYVNEgFSGGEKKRNEILQLLLLEPD 124

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 160 IVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLH-----DINQacryADHLAVMQGGRLVTCG 221
Cdd:cd03217  125 LAILDEPDSGLDIDALRLVAEVINKLREEGKSVLIITHyqrllDYIK----PDRVHVLYDGRIVKSG 187

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

14-176

1.27e-14

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 73.41 E-value: 1.27e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQsGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVN 93
Cdd:TIGR01271 1230 AGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDGVSWNSVTLQTWRKAFGVIPQKVFIFSGTF 1308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    94 VRQLVAYGRSPHNSLWGRLSGADQHSV-DQALQRMELAtlaerpLSD----LSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:TIGR01271 1309 RKNLDPYEQWSDEEIWKVAEEVGLKSViEQFPDKLDFV------LVDggyvLSNGHKQLMCLARSILSKAKILLLDEPSA 1382


                   ....*....
gi 492172462   169 YLD-ISHQV 176
Cdd:TIGR01271 1383 HLDpVTLQI 1391

PRK15112

peptide ABC transporter ATP-binding protein SapF;

19-231

1.99e-14

peptide ABC transporter ATP-binding protein SapF;

Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 70.97 E-value: 1.99e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK--GYSQLSARELACKVAF------------LPQ 84
Cdd:PRK15112  29 VKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHplHFGDYSYRSQRIRMIFqdpstslnprqrISQ 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  85 VLPIPEGVNVrQLVAYGRsphnslwgrlsgadQHSVDQALQRMELatlaerpLSD--------LSGGQRQRAWLAMILAQ 156
Cdd:PRK15112 109 ILDFPLRLNT-DLEPEQR--------------EKQIIETLRQVGL-------LPDhasyyphmLAPGQKQRLGLARALIL 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462 157 DAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAEL 231
Cdd:PRK15112 167 RPKVIIADEALASLDMSMRSQLINLMLELQEKqGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASPL 242

livF

PRK11614

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

1-218

2.17e-14

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 70.68 E-value: 2.17e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQL-SARELACKV 79
Cdd:PRK11614   3 KVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWqTAKIMREAV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQVLPIPEGVNVRQLVAYGrsphnslwGRLsgADQHSVDQALQRME--LATLAERPLS---DLSGGQRQRAWLAMIL 154
Cdd:PRK11614  83 AIVPEGRRVFSRMTVEENLAMG--------GFF--AERDQFQERIKWVYelFPRLHERRIQragTMSGGEQQMLAIGRAL 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 155 AQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:PRK11614 153 MSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVV 216

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

1-226

4.36e-14

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 70.91 E-value: 4.36e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGY----GATRIVQDLSFSPPAGQVTALIGPNGCGKST-------LLKAFARIltpqSGSLSLDGKGYSQ 69
Cdd:PRK09473  10 DALLDVKDLRVTFstpdGDVTAVNDLNFSLRAGETLGIVGESGSGKSQtafalmgLLAANGRI----GGSATFNGREILN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  70 LSAREL----ACKVAFLPQ------------------VLPIPEGVNVRQlvAYGRSphnslwgrLSGADQHSVDQALQRM 127
Cdd:PRK09473  86 LPEKELnklrAEQISMIFQdpmtslnpymrvgeqlmeVLMLHKGMSKAE--AFEES--------VRMLDAVKMPEARKRM 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 128 ELATlaerplSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKT-VITVLHDINQACRYA 206
Cdd:PRK09473 156 KMYP------HEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGIC 229

                        250       260
                 ....*....|....*....|
gi 492172462 207 DHLAVMQGGRLVTCGAPGDV 226
Cdd:PRK09473 230 DKVLVMYAGRTMEYGNARDV 249

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

4-230

4.68e-14

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 71.48 E-value: 4.68e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDigygATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LACKVAFL 82
Cdd:PRK11288 258 LRLDGLK----GPGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDaIRAGIMLC 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 P---------QVLPIPEGVNVrqlvayGRSPHNSLWGRL--SGADQHSVDQALQRMELATL-AERPLSDLSGGQRQRAWL 150
Cdd:PRK11288 334 PedrkaegiiPVHSVADNINI------SARRHHLRAGCLinNRWEAENADRFIRSLNIKTPsREQLIMNLSGGNQQKAIL 407

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 151 AMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVtcgapGDVLTAE 230
Cdd:PRK11288 408 GRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRIA-----GELAREQ 482

PRK13549

xylose transporter ATP-binding subunit; Provisional

3-216

5.20e-14

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 71.11 E-value: 5.20e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILtPQ---SGSLSLDGKGYSQLSARELACK- 78
Cdd:PRK13549   5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVY-PHgtyEGEIIFEGEELQASNIRDTERAg 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  79 VAFLPQVLPIPEGVNVRQLVAYGRSPHNSlwGRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQD 157
Cdd:PRK13549  84 IAIIHQELALVKELSVLENIFLGNEITPG--GIMDYDAMYLrAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQ 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 158 AAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGR 216
Cdd:PRK13549 162 ARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR 220

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

18-185

5.80e-14

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 71.27 E-value: 5.80e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQsGSLSLDGKGYSQLSAREL-----ACKVAFLPQVLPIPEGV 92
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLINSQ-GEIWFDGQPLHNLNRRQLlpvrhRIQVVFQDPNSSLNPRL 379

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQLVAYGRSPHNSlwgRLSGADQHS-VDQALQRMEL-ATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYL 170
Cdd:PRK15134 380 NVLQIIEEGLRVHQP---TLSAAQREQqVIAVMEEVGLdPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSL 456

                        170
                 ....*....|....*
gi 492172462 171 DISHQVELLDLMREL 185
Cdd:PRK15134 457 DKTVQAQILALLKSL 471

PRK10762

D-ribose transporter ATP binding protein; Provisional

28-218

7.48e-14

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 70.80 E-value: 7.48e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  28 AGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGY-------SQLSA-----RELAckvaFLPQvLPIPEGVNVr 95
Cdd:PRK10762  29 PGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVtfngpksSQEAGigiihQELN----LIPQ-LTIAENIFL- 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  96 qlvayGRSPHNSlWGRLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISH 174
Cdd:PRK10762 103 -----GREFVNR-FGRIDWKKMYAeADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDALTDTE 176

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 492172462 175 QVELLDLMRELSAEGKTVITVLH---DINQACryaDHLAVMQGGRLV 218
Cdd:PRK10762 177 TESLFRVIRELKSQGRGIVYISHrlkEIFEIC---DDVTVFRDGQFI 220

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

21-217

7.96e-14

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 70.85 E-value: 7.96e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LACKVAFLPQ-------VLPIPEGV 92
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQrLARGLVYLPEdrqssglYLDAPLAW 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  93 NVRQLVaYGRsphNSLWGRlSGADQHSVDQALQRMELA-TLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:PRK15439 361 NVCALT-HNR---RGFWIK-PARENAVLERYRRALNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVD 435

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 492172462 172 ISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:PRK15439 436 VSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481

PRK10908

cell division ATP-binding protein FtsE;

3-218

1.06e-13

cell division ATP-binding protein FtsE;

Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 68.36 E-value: 1.06e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGY-GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARElackVAF 81
Cdd:PRK10908   1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNRE----VPF 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LpqvlpipegvnvRQLVAYGRSPHNSLWGR-----------LSGAD----QHSVDQALQRMELATLAERPLSDLSGGQRQ 146
Cdd:PRK10908  77 L------------RRQIGMIFQDHHLLMDRtvydnvaipliIAGASgddiRRRVSAALDKVGLLDKAKNFPIQLSGGEQQ 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 147 RAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:PRK10908 145 RVGIARAVVNKPAVLLADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHLH 216

PRK11176

lipid A ABC transporter ATP-binding protein/permease MsbA;

20-227

1.32e-13

lipid A ABC transporter ATP-binding protein/permease MsbA;

Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 70.05 E-value: 1.32e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  20 QDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDG---KGYSQLSARElacKVAFLPQvlpipegvNVRQ 96
Cdd:PRK11176 360 RNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGhdlRDYTLASLRN---QVALVSQ--------NVHL 428

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  97 L-------VAYGRSPHNSLWGRLSGADQ-HSVDqALQRME--LATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:PRK11176 429 FndtiannIAYARTEQYSREQIEEAARMaYAMD-FINKMDngLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEA 507

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 167 TTYLDISHQVELLDLMRELSAEgKTVITVLHDINqACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:PRK11176 508 TSALDTESERAIQAALDELQKN-RTSLVIAHRLS-TIEKADEILVVEDGEIVERGTHAELL 566

ABC_Class2

cd03227

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...

17-198

1.40e-13

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.

Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 66.61 E-value: 1.40e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPagQVTALIGPNGCGKSTLLKAFARILTPQSgslsldgkgysqlsarelackvaflpQVLPIPEGVNVRQ 96
Cdd:cd03227   11 FVPNDVTFGEG--SLTIITGPNGSGKSTILDAIGLALGGAQ--------------------------SATRRRSGVKAGC 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  97 LVAYgrsphnslwgrlsgadqhsvdqalQRMELATLaerpLSDLSGGQRQRAWLAMILA----QDAAIVLLDEPTTYLDI 172
Cdd:cd03227   63 IVAA------------------------VSAELIFT----RLQLSGGEKELSALALILAlaslKPRPLYILDEIDRGLDP 114

                        170       180
                 ....*....|....*....|....*.
gi 492172462 173 SHQVELLDLMRELSAEGKTVITVLHD 198
Cdd:cd03227  115 RDGQALAEAILEHLVKGAQVIVITHL 140

ABCC_SUR1_N

cd03290

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...

19-215

1.55e-13

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 67.74 E-value: 1.55e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACK----VAFLPQVlPIPEGVNV 94
Cdd:cd03290   17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRnrysVAYAAQK-PWLLNATV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  95 RQLVAYGrSPHNSLWGRL---SGADQHSVDqALQRMELATLAERPLsDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:cd03290   96 EENITFG-SPFNKQRYKAvtdACSLQPDID-LLPFGDQTEIGERGI-NLSGGQRQRICVARALYQNTNIVFLDDPFSALD 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 492172462 172 ISHQVELLD--LMRELSAEGKTVITVLHDInQACRYADHLAVMQGG 215
Cdd:cd03290  173 IHLSDHLMQegILKFLQDDKRTLVLVTHKL-QYLPHADWIIAMKDG 217

cyc_pep_trnsptr

TIGR01194

cyclic peptide transporter; This model describes cyclic peptide transporter in bacteria. ...

28-219

1.72e-13

cyclic peptide transporter; This model describes cyclic peptide transporter in bacteria. Bacteria have elaborate pathways for the production of toxins and secondary metabolites. Many such compounds, including syringomycin and pyoverdine are synthesized on non-ribosomal templates consisting of a multienzyme complex. On several occasions the proteins of the complex and transporter protein are present on the same operon. Often times these compounds cross the biological membrane by specific transporters. Syringomycin is an amphipathic, cylclic lipodepsipeptide when inserted into host causes formation of channels, permeable to variety of cations. On the other hand, pyoverdine is a cyclic octa-peptidyl dihydroxyquinoline, which is efficient in sequestering iron for uptake. [Transport and binding proteins, Amino acids, peptides and amines, Transport and binding proteins, Other]

Pssm-ID: 130262 [Multi-domain] Cd Length: 555 Bit Score: 69.60 E-value: 1.72e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   28 AGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELackvaflpqvlpipegvnvRQLVAYGRSPHNs 107
Cdd:TIGR01194 367 QGDIVFIVGENGCGKSTLAKLFCGLYIPQEGEILLDGAAVSADSRDDY-------------------RDLFSAIFADFH- 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  108 LWGRLSGAD---QHSVDQA---LQRMELA------TLAERPLSDLSGGQRQRawLAMILA--QDAAIVLLDEPTTYLDIS 173
Cdd:TIGR01194 427 LFDDLIGPDegeHASLDNAqqyLQRLEIAdkvkieDGGFSTTTALSTGQQKR--LALICAwlEDRPILLFDEWAADQDPA 504

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 492172462  174 -HQVELLDLMRELSAEGKTVITVLHDiNQACRYADHLAVMQGGRLVT 219
Cdd:TIGR01194 505 fKRFFYEELLPDLKRQGKTIIIISHD-DQYFELADQIIKLAAGCIVK 550

PRK13549

xylose transporter ATP-binding subunit; Provisional

3-217

1.79e-13

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 69.57 E-value: 1.79e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHL---DIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKA-FARILTPQSGSLSLDGKGYSQLSARE-LAC 77
Cdd:PRK13549 259 ILEVRNLtawDPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQClFGAYPGRWEGEIFIDGKPVKIRNPQQaIAQ 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 KVAFLPQ-------VLPIPEGVNVrQLVAYGRSphnSLWGRL-SGADQHSVDQALQRMELATL-AERPLSDLSGGQRQRA 148
Cdd:PRK13549 339 GIAMVPEdrkrdgiVPVMGVGKNI-TLAALDRF---TGGSRIdDAAELKTILESIQRLKVKTAsPELAIARLSGGNQQKA 414

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 149 WLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:PRK13549 415 VLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGKL 483

PRK10584

putative ABC transporter ATP-binding protein YbbA; Provisional

2-214

2.10e-13

putative ABC transporter ATP-binding protein YbbA; Provisional

Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 67.50 E-value: 2.10e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLD--IGYGATR--IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLS----AR 73
Cdd:PRK10584   5 NIVEVHHLKksVGQGEHElsILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDeearAK 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  74 ELACKVAFLPQVLPIPEGVNVRQLVaygrsphnSLWGRLSG-ADQHSVDQALQRMELATLAER----PlSDLSGGQRQRA 148
Cdd:PRK10584  85 LRAKHVGFVFQSFMLIPTLNALENV--------ELPALLRGeSSRQSRNGAKALLEQLGLGKRldhlP-AQLSGGEQQRV 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 149 WLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQG 214
Cdd:PRK10584 156 ALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREhGTTLILVTHDLQLAARCDRRLRLVNG 222

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

22-205

2.96e-13

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 69.19 E-value: 2.96e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   22 LSFSPpaGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDgKGYsqlsarelacKVAFLPQVLPIPEGVNVRQLVAYG 101
Cdd:TIGR03719  26 LSFFP--GAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQ-PGI----------KVGYLPQEPQLDPTKTVRENVEEG 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  102 RSPHNSLWGRLS----------------------------GADQHSVDQalqRMELATLAER------PLSDLSGGQRQR 147
Cdd:TIGR03719  93 VAEIKDALDRFNeisakyaepdadfdklaaeqaelqeiidAADAWDLDS---QLEIAMDALRcppwdaDVTKLSGGERRR 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462  148 AWLAMILAQDAAIVLLDEPTTYLDiSHQVELLDlmRELSAEGKTVITVLHDinqacRY 205
Cdd:TIGR03719 170 VALCRLLLSKPDMLLLDEPTNHLD-AESVAWLE--RHLQEYPGTVVAVTHD-----RY 219

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

18-229

3.38e-13

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 69.20 E-value: 3.38e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVNVRQL 97
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFKITIIPQDPVLFSGSLRMNL 1380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    98 VAYGRSPHNSLWGRLSGADQHSVDQALQ---RMELATLAErplsDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISH 174
Cdd:TIGR00957 1381 DPFSQYSDEEVWWALELAHLKTFVSALPdklDHECAEGGE----NLSVGQRQLVCLARALLRKTKILVLDEATAAVDLET 1456

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 492172462   175 QvELLDLMRELSAEGKTVITVLHDINQACRYAdHLAVMQGGRLVTCGAPGDVLTA 229
Cdd:TIGR00957 1457 D-NLIQSTIRTQFEDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLLQQ 1509

ABCC_CFTR2

cd03289

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...

14-176

7.43e-13

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 66.80 E-value: 7.43e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  14 GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQsGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVN 93
Cdd:cd03289   15 GGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDGVSWNSVPLQKWRKAFGVIPQKVFIFSGTF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 VRQLVAYGRSPHNSLWGRLSGADQHSV-DQALQRMELAtlaerpLSD----LSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:cd03289   94 RKNLDPYGKWSDEEIWKVAEEVGLKSViEQFPGQLDFV------LVDggcvLSHGHKQLMCLARSVLSKAKILLLDEPSA 167


                 ....*....
gi 492172462 169 YLD-ISHQV 176
Cdd:cd03289  168 HLDpITYQV 176

PRK13540

cytochrome c biogenesis protein CcmA; Provisional

3-197

7.54e-13

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 65.36 E-value: 7.54e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGkgysQLSARELAC---KV 79
Cdd:PRK13540   1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFER----QSIKKDLCTyqkQL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQVLPIPEGVNVRQlvaygrsphNSLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAA 159
Cdd:PRK13540  77 CFVGHRSGINPYLTLRE---------NCLYDIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAK 147

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 492172462 160 IVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLH 197
Cdd:PRK13540 148 LWLLDEPLVALDELSLLTIITKIQEHRAKGGAVLLTSH 185

PRK10261

glutathione transporter ATP-binding protein; Provisional

19-222

8.70e-13

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 67.57 E-value: 8.70e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTpQSGSLSLDGKGYSQLSARELackVAFLPQVLPIPEGVNVRQLV 98
Cdd:PRK10261  32 VRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLE-QAGGLVQCDKMLLRRRSRQV---IELSEQSAAQMRHVRGADMA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  99 AYGRSPHNSLWGRLSGADQHS----VDQALQRMELATLAERPLS----------------DLSGGQRQRAWLAMILAQDA 158
Cdd:PRK10261 108 MIFQEPMTSLNPVFTVGEQIAesirLHQGASREEAMVEAKRMLDqvripeaqtilsryphQLSGGMRQRVMIAMALSCRP 187

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 159 AIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCGA 222
Cdd:PRK10261 188 AVLIADEPTTALDVTIQAQILQLIKVLQKEmSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGS 252

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

3-218

1.27e-12

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 67.16 E-value: 1.27e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILtPQ---SGSLSLDGKGYSQLSARELACK- 78
Cdd:TIGR02633   1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVY-PHgtwDGEIYWSGSPLKASNIRDTERAg 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   79 VAFLPQVLPIPEGVNVRQLVAYGRS-PHNSlwGRLSGADQ-HSVDQALQRMEL-ATLAERPLSDLSGGQRQRAWLAMILA 155
Cdd:TIGR02633  80 IVIIHQELTLVPELSVAENIFLGNEiTLPG--GRMAYNAMyLRAKNLLRELQLdADNVTRPVGDYGGGQQQLVEIAKALN 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462  156 QDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:TIGR02633 158 KQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHV 220

PRK10522

multidrug transporter membrane component/ATP-binding component; Provisional

29-217

1.89e-12

multidrug transporter membrane component/ATP-binding component; Provisional

Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 66.53 E-value: 1.89e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTllkaFARILT----PQSGSLSLDGkgysqlsarelackvaflpqvlpipEGVNVRQLVAYgRSP 104
Cdd:PRK10522 349 GELLFLIGGNGSGKST----LAMLLTglyqPQSGEILLDG-------------------------KPVTAEQPEDY-RKL 398

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 105 HNS------LWGRLSGADQHSVDQA-----LQRMELA---TLAERPLSD--LSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:PRK10522 399 FSAvftdfhLFDQLLGPEGKPANPAlvekwLERLKMAhklELEDGRISNlkLSKGQKKRLALLLALAEERDILLLDEWAA 478

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 492172462 169 YLD-----ISHQvELLDLMRELsaeGKTVITVLHDiNQACRYADHLAVMQGGRL 217
Cdd:PRK10522 479 DQDphfrrEFYQ-VLLPLLQEM---GKTIFAISHD-DHYFIHADRLLEMRNGQL 527

PRK13538

cytochrome c biogenesis heme-transporting ATPase CcmA;

20-193

1.89e-12

cytochrome c biogenesis heme-transporting ATPase CcmA;

Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 64.44 E-value: 1.89e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  20 QDLSFSPPAGQVTALIGPNGCGKSTLLkafaRILT----PQSGSLSLDGKGYSQLsaRElackvAFLPQVLPI--PEGVN 93
Cdd:PRK13538  18 SGLSFTLNAGELVQIEGPNGAGKTSLL----RILAglarPDAGEVLWQGEPIRRQ--RD-----EYHQDLLYLghQPGIK 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 vRQLVAYgrspHNSLW-GRLSG-ADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:PRK13538  87 -TELTAL----ENLRFyQRLHGpGDDEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAID 161

                        170       180
                 ....*....|....*....|...
gi 492172462 172 iSHQVELL-DLMRELSAEGKTVI 193
Cdd:PRK13538 162 -KQGVARLeALLAQHAEQGGMVI 183

PRK10790

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

7-171

2.42e-12

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 66.28 E-value: 2.42e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   7 QHLDIGYGATRIV-QDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQV 85
Cdd:PRK10790 344 DNVSFAYRDDNLVlQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQGVAMVQQD 423

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  86 lPIPEGVNVRQLVAYGRSphnslwgrlsgADQHSVDQALQRMELATLAeRPLSD------------LSGGQRQRAWLAMI 153
Cdd:PRK10790 424 -PVVLADTFLANVTLGRD-----------ISEEQVWQALETVQLAELA-RSLPDglytplgeqgnnLSVGQKQLLALARV 490

                        170
                 ....*....|....*...
gi 492172462 154 LAQDAAIVLLDEPTTYLD 171
Cdd:PRK10790 491 LVQTPQILILDEATANID 508

modC

PRK11144

molybdenum ABC transporter ATP-binding protein ModC;

27-221

2.76e-12

molybdenum ABC transporter ATP-binding protein ModC;

Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 65.67 E-value: 2.76e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  27 PAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysQLSARElacKVAFLPqvlpiPEGVNVRQLVAYGR-SPH 105
Cdd:PRK11144  22 PAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGR---VLFDAE---KGICLP-----PEKRRIGYVFQDARlFPH 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 106 NSLWGRL----SGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDL 181
Cdd:PRK11144  91 YKVRGNLrygmAKSMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPY 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 492172462 182 MRELSAEGKT-VITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:PRK11144 171 LERLAREINIpILYVSHSLDEILRLADRVVVLEQGKVKAFG 211

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

16-194

3.48e-12

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 66.09 E-value: 3.48e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    16 TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelackVAFLPQVLPIPEGVnVR 95
Cdd:TIGR01271  439 TPVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR-------------ISFSPQTSWIMPGT-IK 504

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    96 QLVAYGRSphnslwgrlsgADQH---SVDQALQRME-LATLAER---PLSD----LSGGQRQRAWLAMILAQDAAIVLLD 164
Cdd:TIGR01271  505 DNIIFGLS-----------YDEYrytSVIKACQLEEdIALFPEKdktVLGEggitLSGGQRARISLARAVYKDADLYLLD 573

                          170       180       190
                   ....*....|....*....|....*....|..
gi 492172462   165 EPTTYLDISHQVELLD--LMRELSAEGKTVIT 194
Cdd:TIGR01271  574 SPFTHLDVVTEKEIFEscLCKLMSNKTRILVT 605

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

3-215

5.14e-12

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 65.81 E-value: 5.14e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462     3 ILKAQHLDIGYGATR--IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQlSARELACKVA 80
Cdd:TIGR01257 1937 ILRLNELTKVYSGTSspAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILT-NISDVHQNMG 2015

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    81 FLPQVLPIPEGVNVRQlvaygrspHNSLWGRLSGADQHSVDQ----ALQRMELATLAERPLSDLSGGQRQRAWLAMILAQ 156
Cdd:TIGR01257 2016 YCPQFDAIDDLLTGRE--------HLYLYARLRGVPAEEIEKvanwSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIG 2087

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462   157 DAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGG 215
Cdd:TIGR01257 2088 CPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKG 2146

ABCC_CFTR1

cd03291

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...

15-215

6.36e-12

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 64.11 E-value: 6.36e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  15 ATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelackVAFLPQVLPIPEGVnV 94
Cdd:cd03291   49 GAPVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR-------------ISFSSQFSWIMPGT-I 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  95 RQLVAYGRSphnslwgrlsgADQH---SVDQALQRME-LATLAER---PLSD----LSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:cd03291  115 KENIIFGVS-----------YDEYrykSVVKACQLEEdITKFPEKdntVLGEggitLSGGQRARISLARAVYKDADLYLL 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 492172462 164 DEPTTYLDISHQVELLD-LMRELSAEgKTVITVLHDINQaCRYADHLAVMQGG 215
Cdd:cd03291  184 DSPFGYLDVFTEKEIFEsCVCKLMAN-KTRILVTSKMEH-LKKADKILILHEG 234

PRK15064

ABC transporter ATP-binding protein; Provisional

4-198

1.37e-11

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 64.14 E-value: 1.37e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   4 LKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKG----YSQLSARELAckv 79
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENAnigyYAQDHAYDFE--- 396

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 aflpqvlpipEGVNVRQLVAYGRSPhnslwgrlsGADQHSVDQALQRMEL-ATLAERPLSDLSGGQRQRAWLAMILAQDA 158
Cdd:PRK15064 397 ----------NDLTLFDWMSQWRQE---------GDDEQAVRGTLGRLLFsQDDIKKSVKVLSGGEKGRMLFGKLMMQKP 457

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 492172462 159 AIVLLDEPTTYLDIsHQVELLDLMRELsAEGkTVITVLHD 198
Cdd:PRK15064 458 NVLVMDEPTNHMDM-ESIESLNMALEK-YEG-TLIFVSHD 494

MK0520

COG2401

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...

6-197

1.83e-11

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];

Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 61.90 E-value: 1.83e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   6 AQHLDIGYGA--TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARiltpqsgslsldgkgysQLSARELACKVAFlp 83
Cdd:COG2401   31 LEAFGVELRVveRYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAG-----------------ALKGTPVAGCVDV-- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  84 qvlpipegvnvrqlvaygrsPHNSLWGRLSGADQ----HSVDQALQRMELATLAE-----RPLSDLSGGQRQRAWLAMIL 154
Cdd:COG2401   92 --------------------PDNQFGREASLIDAigrkGDFKDAVELLNAVGLSDavlwlRRFKELSTGQKFRFRLALLL 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 492172462 155 AQDAAIVLLDEPTTYLDISHQVELLDLMRELSAE-GKTVITVLH 197
Cdd:COG2401  152 AERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRaGITLVVATH 195

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

22-233

2.03e-11

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 63.81 E-value: 2.03e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    22 LSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelackVAFLPQVLPIpEGVNVRQLVAYG 101
Cdd:TIGR00957  657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS-------------VAYVPQQAWI-QNDSLRENILFG 722

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   102 RSPHNSLWGRLSGADQHSVD-QALQRMELATLAERPLsDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLD 180
Cdd:TIGR00957  723 KALNEKYYQQVLEACALLPDlEILPSGDRTEIGEKGV-NLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFE 801

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   181 --LMRELSAEGKTVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDVLT-----AELVC 233
Cdd:TIGR00957  802 hvIGPEGVLKNKTRILVTHGISYLPQ-VDVIIVMSGGKISEMGSYQELLQrdgafAEFLR 860

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

3-231

2.32e-11

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 63.12 E-value: 2.32e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDI-GYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSAREL-ACKVA 80
Cdd:COG3845  257 VLEVENLSVrDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERrRLGVA 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQ-------VLPIPEGVNVrqLVAYGRSPHNSLWGRLsgaDQHSV-DQALQRME----LATLAERPLSDLSGGQRQRA 148
Cdd:COG3845  337 YIPEdrlgrglVPDMSVAENL--ILGRYRRPPFSRGGFL---DRKAIrAFAEELIEefdvRTPGPDTPARSLSGGNQQKV 411

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 149 WLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLT 228
Cdd:COG3845  412 ILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDLDEILALSDRIAVMYEGRIVGEVPAAEATR 491


                 ...
gi 492172462 229 AEL 231
Cdd:COG3845  492 EEI 494

PRK10762

D-ribose transporter ATP binding protein; Provisional

8-217

2.68e-11

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 63.10 E-value: 2.68e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   8 HLDIGYGATRI---------VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LAC 77
Cdd:PRK10762 248 RLDKAPGEVRLkvdnlsgpgVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDgLAN 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 KVAFLPQ-------VLpipeGVNVRQ---LVAYGRspHNSLWGRLSGADQH-SVDQALQRMELATLA-ERPLSDLSGGQR 145
Cdd:PRK10762 328 GIVYISEdrkrdglVL----GMSVKEnmsLTALRY--FSRAGGSLKHADEQqAVSDFIRLFNIKTPSmEQAIGLLSGGNQ 401

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 146 QRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:PRK10762 402 QKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473

ABC_Rad50

cd03240

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...

19-208

3.09e-11

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.

Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 61.08 E-value: 3.09e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPagqVTALIGPNGCGKSTLLKAFARILTpqsGSLSLDGKGYSQLsaRELACKVAFLPQVLPIPEGVNVRQLV 98
Cdd:cd03240   15 RSEIEFFSP---LTLIVGQNGAGKTTIIEALKYALT---GELPPNSKGGAHD--PKLIREGEVRAQVKLAFENANGKKYT 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  99 AYgRSPH---NSLWgrlsgadqhsVDQAlqrmELATLAERPLSDLSGGQRQ------RAWLAMILAQDAAIVLLDEPTTY 169
Cdd:cd03240   87 IT-RSLAileNVIF----------CHQG----ESNWPLLDMRGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTN 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 492172462 170 LDISH-QVELLDLMRE-LSAEGKTVITVLHDINQAcRYADH 208
Cdd:cd03240  152 LDEENiEESLAEIIEErKSQKNFQLIVITHDEELV-DAADH 191

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

22-205

3.69e-11

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 62.83 E-value: 3.69e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  22 LSFSPPA--GqvtaLIGPNGCGKSTLLKAFARILTPQSGSLSLDgKGYsqlsarelacKVAFLPQVLPIPEGVNVRQLV- 98
Cdd:PRK11819  28 LSFFPGAkiG----VLGLNGAGKSTLLRIMAGVDKEFEGEARPA-PGI----------KVGYLPQEPQLDPEKTVRENVe 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  99 ------------------AYGRSPHNS---------LWGRLSGADQHSVDQalqRMELATLAER------PLSDLSGGQR 145
Cdd:PRK11819  93 egvaevkaaldrfneiyaAYAEPDADFdalaaeqgeLQEIIDAADAWDLDS---QLEIAMDALRcppwdaKVTKLSGGER 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 146 QRAWLAMILAQDAAIVLLDEPTTYLDiSHQVELLDlmRELSAEGKTVITVLHDinqacRY 205
Cdd:PRK11819 170 RRVALCRLLLEKPDMLLLDEPTNHLD-AESVAWLE--QFLHDYPGTVVAVTHD-----RY 221

PRK13546

teichoic acids export ABC transporter ATP-binding subunit TagH;

19-227

3.81e-11

teichoic acids export ABC transporter ATP-binding subunit TagH;

Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 61.76 E-value: 3.81e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelackvaflPQVLPIPEGVNvrqlv 98
Cdd:PRK13546  40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE-----------------VSVIAISAGLS----- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  99 aygrsphnslwGRLSGAD----------------QHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:PRK13546  98 -----------GQLTGIEniefkmlcmgfkrkeiKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILV 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVL 227
Cdd:PRK13546 167 IDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVL 231

dppD

PRK11022

dipeptide transporter ATP-binding subunit; Provisional

1-229

4.04e-11

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 62.07 E-value: 4.04e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGAT----RIVQDLSFSPPAGQVTALIGPNGCGKS-TLLKAFARILTP---QSGSLSLDGKGYSQLSA 72
Cdd:PRK11022   1 MALLNVDKLSVHFGDEsapfRAVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYPgrvMAEKLEFNGQDLQRISE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  73 RE----LACKVAFLPQV------------LPIPEGVNVRQlvaygrsphnslwgrlSGADQHSVDQALQRMELATLAErP 136
Cdd:PRK11022  81 KErrnlVGAEVAMIFQDpmtslnpcytvgFQIMEAIKVHQ----------------GGNKKTRRQRAIDLLNQVGIPD-P 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 137 LS-------DLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELS-AEGKTVITVLHDINQACRYADH 208
Cdd:PRK11022 144 ASrldvyphQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQqKENMALVLITHDLALVAEAAHK 223

                        250       260
                 ....*....|....*....|.
gi 492172462 209 LAVMQGGRLVTCGAPGDVLTA 229
Cdd:PRK11022 224 IIVMYAGQVVETGKAHDIFRA 244

ABCG_PDR_domain2

cd03232

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...

17-218

7.91e-11

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 59.56 E-value: 7.91e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFA--RILTPQSGSLSLDGKGYSQLSARElackVAFLPQVLPIPEGVNV 94
Cdd:cd03232   21 QLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAgrKTAGVITGEILINGRPLDKNFQRS----TGYVEQQDVHSPNLTV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  95 RQlvaygrsphnSLwgRLSGAdqhsvdqalqrmelatlaerpLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISH 174
Cdd:cd03232   97 RE----------AL--RFSAL---------------------LRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQA 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 492172462 175 QVELLDLMRELSAEGKTVITVLHDINQAC-RYADHLAVMQ-GGRLV 218
Cdd:cd03232  144 AYNIVRFLKKLADSGQAILCTIHQPSASIfEKFDRLLLLKrGGKTV 189

ABC_UvrA

cd03238

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...

19-218

1.23e-10

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 58.87 E-value: 1.23e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFariltpqsgslsldgkGYSQLSARELACKVAFLPQVLpipegVNVRQLv 98
Cdd:cd03238   11 LQNLDVSIPLNVLVVVTGVSGSGKSTLVNEG----------------LYASGKARLISFLPKFSRNKL-----IFIDQL- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  99 aygrsphnslwgrlsgadQHSVDQALQRMELatlaERPLSDLSGGQRQRAWLAMILAQDA--AIVLLDEPTTYLDISHQV 176
Cdd:cd03238   69 ------------------QFLIDVGLGYLTL----GQKLSTLSGGELQRVKLASELFSEPpgTLFILDEPSTGLHQQDIN 126

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 492172462 177 ELLDLMRELSAEGKTVITVLHDINQACrYADHLAVM------QGGRLV 218
Cdd:cd03238  127 QLLEVIKGLIDLGNTVILIEHNLDVLS-SADWIIDFgpgsgkSGGKVV 173

PRK15079

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

19-221

1.75e-10

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 60.11 E-value: 1.75e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEG-----VN 93
Cdd:PRK15079  37 VDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVRSDIQMIFQDPLAslnprMT 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  94 VRQLVAygrSPHNSLWGRLSGADqhsVDQALQRME-----LATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:PRK15079 117 IGEIIA---EPLRTYHPKLSRQE---VKDRVKAMMlkvglLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVS 190

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 492172462 169 YLDISHQVELLDLMRELSAE-GKTVITVLHDINQACRYADHLAVMQGGRLVTCG 221
Cdd:PRK15079 191 ALDVSIQAQVVNLLQQLQREmGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELG 244

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

121-221

2.19e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 60.13 E-value: 2.19e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 121 DQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDIN 200
Cdd:NF000106 126 DELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYME 205

                         90       100
                 ....*....|....*....|.
gi 492172462 201 QACRYADHLAVMQGGRLVTCG 221
Cdd:NF000106 206 EAEQLAHELTVIDRGRVIADG 226

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

29-218

2.58e-10

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 60.13 E-value: 2.58e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARE-LACKVAFLPQVLPIPEGVNVRQLVAYGRSPHNS 107
Cdd:PRK10982  24 HSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEaLENGISMVHQELNLVLQRSVMDNMWLGRYPTKG 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 108 LWgrlsgadqhsVDQA-LQRMELATLAE--------RPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYL---DISHq 175
Cdd:PRK10982 104 MF----------VDQDkMYRDTKAIFDEldididprAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLtekEVNH- 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 492172462 176 veLLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:PRK10982 173 --LFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWI 213

PLN03211

ABC transporter G-25; Provisional

29-197

2.98e-10

ABC transporter G-25; Provisional

Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 60.28 E-value: 2.98e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFA----------------RILTPQ----SGSLSLDGKGYSQLSARE--LACKVAFLPQVL 86
Cdd:PLN03211  94 GEILAVLGPSGSGKSTLLNALAgriqgnnftgtilannRKPTKQilkrTGFVTQDDILYPHLTVREtlVFCSLLRLPKSL 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  87 PIPEgvnvrqlvaygrsphnslwgRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:PLN03211 174 TKQE--------------------KILVAESVISELGLTKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEP 233

                        170       180       190
                 ....*....|....*....|....*....|.
gi 492172462 167 TTYLDISHQVELLDLMRELSAEGKTVITVLH 197
Cdd:PLN03211 234 TSGLDATAAYRLVLTLGSLAQKGKTIVTSMH 264

3a01203

TIGR00954

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...

18-197

3.52e-10

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 59.76 E-value: 3.52e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelaCKVAFLPQVLPIPEGvNVRQL 97
Cdd:TIGR00954 467 LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAK-----------GKLFYVPQRPYMTLG-TLRDQ 534

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   98 VAYGRSPHNSLWGRLSGADqhsVDQALQRMELATLAERPLS---------DLSGGQRQRAWLAMILAQDAAIVLLDEPTT 168
Cdd:TIGR00954 535 IIYPDSSEDMKRRGLSDKD---LEQILDNVQLTHILEREGGwsavqdwmdVLSGGEKQRIAMARLFYHKPQFAILDECTS 611

                         170       180       190
                  ....*....|....*....|....*....|
gi 492172462  169 ylDISHQVEllDLMRELSAE-GKTVITVLH 197
Cdd:TIGR00954 612 --AVSVDVE--GYMYRLCREfGITLFSVSH 637

PLN03232

ABC transporter C family member; Provisional

19-194

7.63e-10

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 59.22 E-value: 7.63e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSlSLDGKGysqlsarelacKVAFLPQVlPIPEGVNVRQLV 98
Cdd:PLN03232  633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAETS-SVVIRG-----------SVAYVPQV-SWIFNATVRENI 699

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   99 AYGRSPHNSLWGRL--SGADQHSVDQALQRmELATLAERPLsDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD--ISH 174
Cdd:PLN03232  700 LFGSDFESERYWRAidVTALQHDLDLLPGR-DLTEIGERGV-NISGGQKQRVSMARAVYSNSDIYIFDDPLSALDahVAH 777

                         170       180
                  ....*....|....*....|
gi 492172462  175 QVELLDLMRELSAEGKTVIT 194
Cdd:PLN03232  778 QVFDSCMKDELKGKTRVLVT 797

PRK13543

heme ABC exporter ATP-binding protein CcmA;

3-194

1.57e-09

heme ABC exporter ATP-binding protein CcmA;

Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 56.40 E-value: 1.57e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysQLSARELACKVAFL 82
Cdd:PRK13543  11 LLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGK---TATRGDRSRFMAYL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  83 PQVLPIPEGVNVRQLVAYgrspHNSLWGRLSgadQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVL 162
Cdd:PRK13543  88 GHLPGLKADLSTLENLHF----LCGLHGRRA---KQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWL 160

                        170       180       190
                 ....*....|....*....|....*....|....
gi 492172462 163 LDEPTTYLDIShQVELLDLM--RELSAEGKTVIT 194
Cdd:PRK13543 161 LDEPYANLDLE-GITLVNRMisAHLRGGGAALVT 193

PRK11147

ABC transporter ATPase component; Reviewed

1-172

1.66e-09

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 58.04 E-value: 1.66e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKafarILtpqSGSLSLDgKGYSQLsARELacKVA 80
Cdd:PRK11147   1 MSLISIHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMK----IL---NGEVLLD-DGRIIY-EQDL--IVA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQVLP----------IPEGVN-----------VRQLVAYGRSP--------------HNSLWgRLsgadQHSVDQALQ 125
Cdd:PRK11147  70 RLQQDPPrnvegtvydfVAEGIEeqaeylkryhdISHLVETDPSEknlnelaklqeqldHHNLW-QL----ENRINEVLA 144

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 492172462 126 RMELAtlAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDI 172
Cdd:PRK11147 145 QLGLD--PDAALSSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDI 189

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

29-200

2.27e-09

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 54.69 E-value: 2.27e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLdgkgysqlsarelackvaflpqvlpipegvnvrqlvaygrsphnsl 108
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIY---------------------------------------------- 35

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   109 wgrLSGADQHSVDQALQRMELATlaeRPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLD------LM 182
Cdd:smart00382  36 ---IDGEDILEEVLDQLLLIIVG---GKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLleelrlLL 109

                          170
                   ....*....|....*...
gi 492172462   183 RELSAEGKTVITVLHDIN 200
Cdd:smart00382 110 LLKSEKNLTVILTTNDEK 127

PRK10636

putative ABC transporter ATP-binding protein; Provisional

3-198

2.34e-09

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 57.49 E-value: 2.34e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLdGKG-----YSQLSARELAC 77
Cdd:PRK10636 312 LLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-AKGiklgyFAQHQLEFLRA 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  78 KVAFLPQVLPIPEGVNVRQLVAYgrsphnsLWGRLSGADQhsVDQALQRmelatlaerplsdLSGGQRQRAWLAMILAQD 157
Cdd:PRK10636 391 DESPLQHLARLAPQELEQKLRDY-------LGGFGFQGDK--VTEETRR-------------FSGGEKARLVLALIVWQR 448

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 492172462 158 AAIVLLDEPTTYLDISHQVELLDLMRELsaEGKTVItVLHD 198
Cdd:PRK10636 449 PNLLLLDEPTNHLDLDMRQALTEALIDF--EGALVV-VSHD 486

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

19-232

2.73e-09

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 57.44 E-value: 2.73e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysQLSARELAC--KVAFLPQVLPIPEGVNVRQ 96
Cdd:NF033858 282 VDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQ---PVDAGDIATrrRVGYMSQAFSLYGELTVRQ 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  97 -LVAYGRSPHnslwgrLSGADQHS-VDQALQRMELATLAERPLSDLSGGQRQRAWL--AMILAQDaaIVLLDEPTTYLDI 172
Cdd:NF033858 359 nLELHARLFH------LPAAEIAArVAEMLERFDLADVADALPDSLPLGIRQRLSLavAVIHKPE--LLILDEPTSGVDP 430

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462 173 SHQVELLDLMRELSAEGKTVITV-LHDINQACRyADHLAVMQGGRLVTCGAPgdvltAELV 232
Cdd:NF033858 431 VARDMFWRLLIELSREDGVTIFIsTHFMNEAER-CDRISLMHAGRVLASDTP-----AALV 485

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

29-224

3.00e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 57.43 E-value: 3.00e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    29 GQVTALIGPNGCGKSTLLKAFARILTP---QSGSLSLDGKGYSQLSARELA-CKvaflPQVLPIPEgVNVR---QLVAYG 101
Cdd:TIGR00956  789 GTLTALMGASGAGKTTLLNVLAERVTTgviTGGDRLVNGRPLDSSFQRSIGyVQ----QQDLHLPT-STVReslRFSAYL 863

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   102 RSPHNslwgrLSGADQHS-VDQALQRMELATLAER----PLSDLSGGQRQRAWLAMIL-AQDAAIVLLDEPTTYLDISHQ 175
Cdd:TIGR00956  864 RQPKS-----VSKSEKMEyVEEVIKLLEMESYADAvvgvPGEGLNVEQRKRLTIGVELvAKPKLLLFLDEPTSGLDSQTA 938

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 492172462   176 VELLDLMRELSAEGKTVITVLH----DINQAcryADHLAVMQ-GGRLVTCGAPG 224
Cdd:TIGR00956  939 WSICKLMRKLADHGQAILCTIHqpsaILFEE---FDRLLLLQkGGQTVYFGDLG 989

YbjD

COG3593

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...

17-197

3.23e-09

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];

Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 56.55 E-value: 3.23e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFsPPAGQVTALIGPNGCGKSTLLKAFARILTPQSG-SLSL-DGKGYSQLSARELACKVAF-------LPQVLP 87
Cdd:COG3593   12 RSIKDLSI-ELSDDLTVLVGENNSGKSSILEALRLLLGPSSSrKFDEeDFYLGDDPDLPEIEIELTFgsllsrlLRLLLK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  88 IPEGVNVRQLVAYGRSPHNSLWGRLS---------GADQHSVDQALQRMELATLA-----------ERPLSDLSGGQRQR 147
Cdd:COG3593   91 EEDKEELEEALEELNEELKEALKALNellseylkeLLDGLDLELELSLDELEDLLkslslriedgkELPLDRLGSGFQRL 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 148 AWLAMILA-------QDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLH 197
Cdd:COG3593  171 ILLALLSAlaelkraPANPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNQVIITTH 227

uvra

TIGR00630

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...

134-227

3.63e-09

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 56.95 E-value: 3.63e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  134 ERPLSDLSGGQRQRAWLAMILAQDAAIVL--LDEPTTYLdisHQVE---LLDLMRELSAEGKTVITVLHDiNQACRYADH 208
Cdd:TIGR00630 483 SRAAGTLSGGEAQRIRLATQIGSGLTGVLyvLDEPSIGL---HQRDnrrLINTLKRLRDLGNTLIVVEHD-EDTIRAADY 558

                          90       100
                  ....*....|....*....|....*
gi 492172462  209 L------AVMQGGRLVTCGAPGDVL 227
Cdd:TIGR00630 559 VidigpgAGEHGGEVVASGTPEEIL 583

PLN03130

ABC transporter C family member; Provisional

22-230

4.86e-09

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 56.67 E-value: 4.86e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   22 LSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGVnvrqlVAYG 101
Cdd:PLN03130 1258 LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKVLGIIPQAPVLFSGT-----VRFN 1332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  102 RSP---HN--SLWGRLSGAdqHSVDqALQRMELATLAE--RPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISH 174
Cdd:PLN03130 1333 LDPfneHNdaDLWESLERA--HLKD-VIRRNSLGLDAEvsEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRT 1409

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  175 QVELLDLMRElsaEGK--TVITVLHDINQA--CryaDHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:PLN03130 1410 DALIQKTIRE---EFKscTMLIIAHRLNTIidC---DRILVLDAGRVVEFDTPENLLSNE 1463

PLN03073

ABC transporter F family; Provisional

12-217

4.89e-09

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 56.41 E-value: 4.89e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GY-GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKG----YSQLSARELACKVAFLPQVL 86
Cdd:PLN03073 517 GYpGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSAKVrmavFSQHHVDGLDLSSNPLLYMM 596

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  87 PIPEGVNVRQLVAygrspHNSLWGrLSGadqhsvdqalqrmelaTLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:PLN03073 597 RCFPGVPEQKLRA-----HLGSFG-VTG----------------NLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEP 654

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 492172462 167 TTYLDIShQVELldLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRL 217
Cdd:PLN03073 655 SNHLDLD-AVEA--LIQGLVLFQGGVLMVSHDEHLISGSVDELWVVSEGKV 702

PLN03232

ABC transporter C family member; Provisional

8-230

6.63e-09

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 56.14 E-value: 6.63e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462    8 HLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLP 87
Cdd:PLN03232 1241 HLRYRPGLPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIPQSPV 1320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   88 IPEGVNVRQLVAYgrSPHN--SLWGRLSGAdqhSVDQALQRMELATLAE--RPLSDLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:PLN03232 1321 LFSGTVRFNIDPF--SEHNdaDLWEALERA---HIKDVIDRNPFGLDAEvsEGGENFSVGQRQLLSLARALLRRSKILVL 1395

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462  164 DEPTTYLDISHQVELLDLMRElSAEGKTVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:PLN03232 1396 DEATASVDVRTDSLIQRTIRE-EFKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRD 1460

COG3950

Predicted ATP-binding protein involved in virulence [General function prediction only];

21-185

7.53e-09

Predicted ATP-binding protein involved in virulence [General function prediction only];

Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 55.00 E-value: 7.53e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPPAGqVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK------------------GYS---QLSARELACKV 79
Cdd:COG3950   18 EIDFDNPPR-LTVLVGENGSGKTTLLEAIALALSGLLSRLDDVKFrkllirngefgdsaklilYYGtsrLLLDGPLKKLE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  80 AFLPQVLP--------IPEGVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQ--------------RMELATL----- 132
Cdd:COG3950   97 RLKEEYFSrldgydslLDEDSNLREFLEWLREYLEDLENKLSDELDEKLEAVREalnkllpdfkdiriDRDPGRLvildk 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 133 --AERPLSDLSGGQRQR-AWLAMILAQDA-------------AIVLLDEPTTYLDISHQVELLDLMREL 185
Cdd:COG3950  177 ngEELPLNQLSDGERSLlALVGDLARRLAelnpalenplegeGIVLIDEIDLHLHPKWQRRILPDLRKI 245

PTZ00243

ABC transporter; Provisional

22-223

1.06e-08

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 55.56 E-value: 1.06e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   22 LSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVLPIPEGvNVRQLVayg 101
Cdd:PTZ00243 1329 VSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRELRRQFSMIPQDPVLFDG-TVRQNV--- 1404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  102 rSPhnslwgrLSGADQHSVDQALqrmELATLAERPLSDLSG--------------GQRQRAWLA-MILAQDAAIVLLDEP 166
Cdd:PTZ00243 1405 -DP-------FLEASSAEVWAAL---ELVGLRERVASESEGidsrvleggsnysvGQRQLMCMArALLKKGSGFILMDEA 1473

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462  167 TTYLD--ISHQVElLDLMRELSAEgkTVITVLHDINQACRYaDHLAVMQGGRLVTCGAP 223
Cdd:PTZ00243 1474 TANIDpaLDRQIQ-ATVMSAFSAY--TVITIAHRLHTVAQY-DKIIVMDHGAVAEMGSP 1528

PRK15064

ABC transporter ATP-binding protein; Provisional

34-217

1.07e-08

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 55.28 E-value: 1.07e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  34 LIGPNGCGKSTLLKAFARILTPQSGSLSLDgkgysqlsareLACKVAFLPQVLPIPEGVNVRQLVAYGrspHNSLWGRLS 113
Cdd:PRK15064  32 LIGANGCGKSTFMKILGGDLEPSAGNVSLD-----------PNERLGKLRQDQFAFEEFTVLDTVIMG---HTELWEVKQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 114 GAD------QHSVDQALQRMEL-ATLAE--------R-----------------PLSDLSGGQRQRAWLAMILAQDAAIV 161
Cdd:PRK15064  98 ERDriyalpEMSEEDGMKVADLeVKFAEmdgytaeaRagelllgvgipeeqhygLMSEVAPGWKLRVLLAQALFSNPDIL 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 492172462 162 LLDEPTTYLDIsHQVELLDlmRELSAEGKTVITVLHD---INQACryaDHLAVMQGGRL 217
Cdd:PRK15064 178 LLDEPTNNLDI-NTIRWLE--DVLNERNSTMIIISHDrhfLNSVC---THMADLDYGEL 230

ABCC_SUR2

cd03288

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...

29-230

1.43e-08

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 54.14 E-value: 1.43e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVlPIPEGVNVR-QLVAYGRSPHNS 107
Cdd:cd03288   47 GQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQD-PILFSGSIRfNLDPECKCTDDR 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 108 LWGRLSGADQHSVDQALQRMELATLAERPlSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSA 187
Cdd:cd03288  126 LWEALEIAQLKNMVKSLPGGLDAVVTEGG-ENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFA 204

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 492172462 188 EgKTVITVLHDINQACRyADHLAVMQGGRLVTCGAPGDVLTAE 230
Cdd:cd03288  205 D-RTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLLAQE 245

ABC_UvrA_II

cd03271

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...

19-223

1.53e-08

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 54.16 E-value: 1.53e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLL-----KAFARIL--------------------------------TPQSGSLS 61
Cdd:cd03271   11 LKNIDVDIPLGVLTCVTGVSGSGKSSLIndtlyPALARRLhlkkeqpgnhdrieglehidkvividqspigrTPRSNPAT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  62 ldgkgYSQL--SARELACKVA----FLPQVLPipegvnvrqlVAY-GRSPHNSLwgrlsgadQHSVDQALQRME------ 128
Cdd:cd03271   91 -----YTGVfdEIRELFCEVCkgkrYNRETLE----------VRYkGKSIADVL--------DMTVEEALEFFEnipkia 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 129 --LATLAE---------RPLSDLSGGQRQRAWLAMILAQDA---AIVLLDEPTTYL---DISHqveLLDLMRELSAEGKT 191
Cdd:cd03271  148 rkLQTLCDvglgyiklgQPATTLSGGEAQRIKLAKELSKRStgkTLYILDEPTTGLhfhDVKK---LLEVLQRLVDKGNT 224

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 492172462 192 VITVLHDINQAcRYADHLAVM------QGGRLVTCGAP 223
Cdd:cd03271  225 VVVIEHNLDVI-KCADWIIDLgpeggdGGGQVVASGTP 261

GguA

NF040905

sugar ABC transporter ATP-binding protein;

20-218

1.64e-08

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 54.80 E-value: 1.64e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  20 QDLSFSPPAGQVTALIGPNGCGKSTLLKafarILT---PQ---SGSLSLDG-----KGYSQLSAR-------ELAckvaF 81
Cdd:NF040905  18 DDVNLSVREGEIHALCGENGAGKSTLMK----VLSgvyPHgsyEGEILFDGevcrfKDIRDSEALgiviihqELA----L 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  82 LPQvLPIPEGV---NVRqlvaygrsphnSLWGRLSGADQHSvdQALQRMELATLAERP---LSDLSGGQRQRAWLAMILA 155
Cdd:NF040905  90 IPY-LSIAENIflgNER-----------AKRGVIDWNETNR--RARELLAKVGLDESPdtlVTDIGVGKQQLVEIAKALS 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492172462 156 QDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLV 218
Cdd:NF040905 156 KDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVLRDGRTI 218

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

16-234

2.95e-08

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 53.87 E-value: 2.95e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  16 TRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELackvaflpqvlpipegvnvR 95
Cdd:PRK10938  16 TKTLQLPSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEQL-------------------Q 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  96 QLVA--YGR------SPHNSLWGRlSGAD--QHSVDQALQRMELAT------LAERPLSDLSGGQRQRAWLAMILAQDAA 159
Cdd:PRK10938  77 KLVSdeWQRnntdmlSPGEDDTGR-TTAEiiQDEVKDPARCEQLAQqfgitaLLDRRFKYLSTGETRKTLLCQALMSEPD 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462 160 IVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVTCGAPGDVLTAELVCQ 234
Cdd:PRK10938 156 LLILDEPFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEILQQALVAQ 230

PRK10789

SmdA family multidrug ABC transporter permease/ATP-binding protein;

18-221

3.19e-08

SmdA family multidrug ABC transporter permease/ATP-binding protein;

Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 53.95 E-value: 3.19e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQVlPIPEGVNVRQL 97
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVSQT-PFLFSDTVANN 408

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  98 VAYGRsphnslwgrlSGADQHSVDQALQrmeLATLAERPLS--------------DLSGGQRQRAWLAMILAQDAAIVLL 163
Cdd:PRK10789 409 IALGR----------PDATQQEIEHVAR---LASVHDDILRlpqgydtevgergvMLSGGQKQRISIARALLLNAEILIL 475

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462 164 DEPTTYLDISHQVELLDLMRELSaEGKTVITVLHDINqACRYADHLAVMQGGRLVTCG 221
Cdd:PRK10789 476 DDALSAVDGRTEHQILHNLRQWG-EGRTVIISAHRLS-ALTEASEILVMQHGHIAQRG 531

tagH

PRK13545

teichoic acids export protein ATP-binding subunit; Provisional

21-201

4.08e-08

teichoic acids export protein ATP-binding subunit; Provisional

Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 53.74 E-value: 4.08e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  21 DLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGkgysqlSARELACKVAFLPQVLPIpEGVNVRQLvay 100
Cdd:PRK13545  42 NISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG------SAALIAISSGLNGQLTGI-ENIELKGL--- 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 101 grsphnsLWGRLSGADQHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLD 180
Cdd:PRK13545 112 -------MMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLD 184

                        170       180
                 ....*....|....*....|.
gi 492172462 181 LMRELSAEGKTVITVLHDINQ 201
Cdd:PRK13545 185 KMNEFKEQGKTIFFISHSLSQ 205

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

19-230

5.04e-08

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 53.19 E-value: 5.04e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARElACKVAFlpqVLPIPE-------- 90
Cdd:PRK10982 264 IRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANE-AINHGF---ALVTEErrstgiya 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 --GVNVRQLVAYGRSPHNSlWGRLSGADQHSVDQ-ALQRMELATLAER-PLSDLSGGQRQRAWLAMILAQDAAIVLLDEP 166
Cdd:PRK10982 340 ylDIGFNSLISNIRNYKNK-VGLLDNSRMKSDTQwVIDSMRVKTPGHRtQIGSLSGGNQQKVIIGRWLLTQPEILMLDEP 418

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492172462 167 TTYLDISHQVELLDLMRELSAEGKTVITVLHDINQACRYADHLAVMQGGRLVtcgapGDVLTAE 230
Cdd:PRK10982 419 TRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGLVA-----GIVDTKT 477

PRK10636

putative ABC transporter ATP-binding protein; Provisional

29-198

5.41e-08

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 53.25 E-value: 5.41e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKgysqlsarelaCKVAFLPQVLPIPEgVNVRQLVAYGRSPHNSL 108
Cdd:PRK10636  27 GQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGN-----------WQLAWVNQETPALP-QPALEYVIDGDREYRQL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 109 WGRLSGADQHSVDQALQ--------------RMELATLA----------ERPLSDLSGGQRQRAWLAMILAQDAAIVLLD 164
Cdd:PRK10636  95 EAQLHDANERNDGHAIAtihgkldaidawtiRSRAASLLhglgfsneqlERPVSDFSGGWRMRLNLAQALICRSDLLLLD 174

                        170       180       190
                 ....*....|....*....|....*....|....
gi 492172462 165 EPTTYLDIShqvELLDLMRELSAEGKTVITVLHD 198
Cdd:PRK10636 175 EPTNHLDLD---AVIWLEKWLKSYQGTLILISHD 205

ABCG_PDR_domain1

cd03233

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...

18-218

1.36e-07

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 50.72 E-value: 1.36e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQ---SGSLSLDGKGYSQLSARelaCK--VAFLPQV-LPIPEg 91
Cdd:cd03233   22 ILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEK---YPgeIIYVSEEdVHFPT- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 VNVRQLVAYGRsphnslwgRLSGADQhsvdqalqrmelatlaerpLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:cd03233   98 LTVRETLDFAL--------RCKGNEF-------------------VRGISGGERKRVSIAEALVSRASVLCWDNSTRGLD 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 492172462 172 ISHQVELLDLMRELSAEGKTVITVlhDINQACR--YA--DHLAVMQGGRLV 218
Cdd:cd03233  151 SSTALEILKCIRTMADVLKTTTFV--SLYQASDeiYDlfDKVLVLYEGRQI 199

ycf16

CHL00131

sulfate ABC transporter protein; Validated

2-221

1.37e-07

sulfate ABC transporter protein; Validated

Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 51.18 E-value: 1.37e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   2 SILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFA-----RILtpqSGSLSLDGKGYSQLSARELA 76
Cdd:CHL00131   6 PILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAghpayKIL---EGDILFKGESILDLEPEERA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  77 CKVAFLPQVLP--IPeGVNVRQL--VAYgRSPHNSLwgRLSGADQHSVDQAL-QRMELATLAERPLS-----DLSGGQRQ 146
Cdd:CHL00131  83 HLGIFLAFQYPieIP-GVSNADFlrLAY-NSKRKFQ--GLPELDPLEFLEIInEKLKLVGMDPSFLSrnvneGFSGGEKK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 147 R-AWLAMILAqDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHdinqacrYA--------DHLAVMQGGRL 217
Cdd:CHL00131 159 RnEILQMALL-DSELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITH-------YQrlldyikpDYVHVMQNGKI 230


                 ....
gi 492172462 218 VTCG 221
Cdd:CHL00131 231 IKTG 234

ABC_UvrA_I

cd03270

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...

134-221

1.75e-07

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 50.72 E-value: 1.75e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 134 ERPLSDLSGGQRQRAWLAMILAQDAAIVL--LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDiNQACRYADHL-- 209
Cdd:cd03270  132 SRSAPTLSGGEAQRIRLATQIGSGLTGVLyvLDEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVEHD-EDTIRAADHVid 210

                         90
                 ....*....|....*.
gi 492172462 210 ----AVMQGGRLVTCG 221
Cdd:cd03270  211 igpgAGVHGGEIVAQG 226

PTZ00265

multidrug resistance protein (mdr1); Provisional

18-212

2.15e-07

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 51.57 E-value: 2.15e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSL-DGKGYSQLSARELACKVAFLPQVlPIPEGVNVRQ 96
Cdd:PTZ00265  400 IYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIInDSHNLKDINLKWWRSKIGVVSQD-PLLFSNSIKN 478

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   97 LVAY------------------------GRSPHNSLWGRLSGaDQHSVDQALQRMEL----------------------- 129
Cdd:PTZ00265  479 NIKYslyslkdlealsnyynedgndsqeNKNKRNSCRAKCAG-DLNDMSNTTDSNELiemrknyqtikdsevvdvskkvl 557

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  130 ------------ATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSA-EGKTVITVL 196
Cdd:PTZ00265  558 ihdfvsalpdkyETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGnENRITIIIA 637

                         250
                  ....*....|....*.
gi 492172462  197 HDINqACRYADHLAVM 212
Cdd:PTZ00265  638 HRLS-TIRYANTIFVL 652

PTZ00243

ABC transporter; Provisional

18-225

3.28e-07

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 51.32 E-value: 3.28e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   18 IVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLsldgkgysqLSARElackVAFLPQVLPIpegvnvrqL 97
Cdd:PTZ00243  675 LLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV---------WAERS----IAYVPQQAWI--------M 733

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   98 VAYGRSphNSLW------GRLSGA---DQHSVDQALQRMELAT-LAERPLsDLSGGQRQRAWLAMILAQDAAIVLLDEPT 167
Cdd:PTZ00243  734 NATVRG--NILFfdeedaARLADAvrvSQLEADLAQLGGGLETeIGEKGV-NLSGGQKARVSLARAVYANRDVYLLDDPL 810

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462  168 TYLDiSHQVELldLMREL---SAEGKTVITVLHDINQACRyADHLAVMQGGRLVTCGAPGD 225
Cdd:PTZ00243  811 SALD-AHVGER--VVEECflgALAGKTRVLATHQVHVVPR-ADYVVALGDGRVEFSGSSAD 867

UvrA

COG0178

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];

119-226

4.01e-07

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];

Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 50.80 E-value: 4.01e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 119 SVDQALQRME--------LATLAE---------RPLSDLSGGQRQRAWLAMILAQDA---AIVLLDEPTTYL---DISHq 175
Cdd:COG0178  789 TVEEALEFFEnipkiarkLQTLQDvglgyiklgQPATTLSGGEAQRVKLASELSKRStgkTLYILDEPTTGLhfhDIRK- 867

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 176 veLLDLMRELSAEGKTVITVLHD---InqacRYADHLAVM------QGGRLVTCGAPGDV 226
Cdd:COG0178  868 --LLEVLHRLVDKGNTVVVIEHNldvI----KTADWIIDLgpeggdGGGEIVAEGTPEEV 921

COG3910

Predicted ATPase [General function prediction only];

19-197

5.43e-07

Predicted ATPase [General function prediction only];

Pssm-ID: 443116 [Multi-domain] Cd Length: 239 Bit Score: 49.38 E-value: 5.43e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  19 VQDLSFSPPagqVTALIGPNGCGKSTLLKAFARiltpqsgSLSLDGKGYSQL-------SARELAckvaflpQVLpipeg 91
Cdd:COG3910   30 LEGLEFHPP---VTFFVGENGSGKSTLLEAIAV-------AAGFNPEGGSKNfrfstreSESALG-------EYL----- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  92 vnvrQLVaygRSPHNSLWGR-LSGADQHSVDQALQRMELATLA------ERPLSDLSGGQrqrAWLAMILA--QDAAIVL 162
Cdd:COG3910   88 ----RLS---RGLPKPRDGFfLRAESFFNVATYLDELAAEGPGildsygGRSLHEQSHGE---SFLALFENrfRGNGLYL 157

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 492172462 163 LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLH 197
Cdd:COG3910  158 LDEPEAALSPSRQLALLALIHDLVREGSQFIIATH 192

uvra

TIGR00630

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...

120-226

6.09e-07

Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 50.40 E-value: 6.09e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  120 VDQALQRMELAtlaeRPLSDLSGGQRQRAWLAMILAQDA---AIVLLDEPTTYL---DISHqveLLDLMRELSAEGKTVI 193
Cdd:TIGR00630 814 CDVGLGYIRLG----QPATTLSGGEAQRIKLAKELSKRStgrTLYILDEPTTGLhfdDIKK---LLEVLQRLVDKGNTVV 886

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 492172462  194 TVLHDINqACRYADHLAVM------QGGRLVTCGAPGDV 226
Cdd:TIGR00630 887 VIEHNLD-VIKTADYIIDLgpeggdGGGTVVASGTPEEV 924

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

11-171

8.25e-07

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 49.63 E-value: 8.25e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  11 IGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKafarILT---PQ--SGSLSLDGK---------------GY--S 68
Cdd:PRK10938 268 VSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLS----LITgdhPQgySNDLTLFGRrrgsgetiwdikkhiGYvsS 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  69 QLsarELACKVAflpqvlpipegVNVRQLVAYGRSPHNSLWGRLSGADQHSVDQALQRMEL-ATLAERPLSDLSGGQRQR 147
Cdd:PRK10938 344 SL---HLDYRVS-----------TSVRNVILSGFFDSIGIYQAVSDRQQKLAQQWLDILGIdKRTADAPFHSLSWGQQRL 409

                        170       180
                 ....*....|....*....|....
gi 492172462 148 AWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:PRK10938 410 ALIVRALVKHPTLLILDEPLQGLD 433

sufC

PRK09580

cysteine desulfurase ATPase component; Reviewed

3-221

1.07e-06

cysteine desulfurase ATPase component; Reviewed

Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 48.63 E-value: 1.07e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   3 ILKAQHLDIGYGATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFA--RILTPQSGSLSLDGKGYSQLSARELACKVA 80
Cdd:PRK09580   1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAgrEDYEVTGGTVEFKGKDLLELSPEDRAGEGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  81 FLPQVLP--IPegvnvrqlvayGRSPHNSLWGRLSGADQHSVDQALQRMELATLAERPLSDL---------------SGG 143
Cdd:PRK09580  81 FMAFQYPveIP-----------GVSNQFFLQTALNAVRSYRGQEPLDRFDFQDLMEEKIALLkmpedlltrsvnvgfSGG 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 144 QRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHdINQACRY--ADHLAVMQGGRLVTCG 221
Cdd:PRK09580 150 EKKRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDGKRSFIIVTH-YQRILDYikPDYVHVLYQGRIVKSG 228

PRK15093

peptide ABC transporter ATP-binding protein SapD;

1-229

2.28e-06

peptide ABC transporter ATP-binding protein SapD;

Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 47.87 E-value: 2.28e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   1 MSILKAQHLDIGY----GATRIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARIlTPQSGSLSLDGKGYS-----QLS 71
Cdd:PRK15093   1 MPLLDIRNLTIEFktsdGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGV-TKDNWRVTADRMRFDdidllRLS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  72 ARE----LACKVAFL---PQVLPIPEGVNVRQLV-AYGRSPHNSLWGRLSGADQHSVDQALQRMEL----ATLAERPLsD 139
Cdd:PRK15093  80 PRErrklVGHNVSMIfqePQSCLDPSERVGRQLMqNIPGWTYKGRWWQRFGWRKRRAIELLHRVGIkdhkDAMRSFPY-E 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 140 LSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVL-HDINQACRYADHLAVMQGGRLV 218
Cdd:PRK15093 159 LTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLIsHDLQMLSQWADKINVLYCGQTV 238

                        250
                 ....*....|.
gi 492172462 219 TCGAPGDVLTA 229
Cdd:PRK15093 239 ETAPSKELVTT 249

PLN03140

ABC transporter G family member; Provisional

23-224

3.51e-06

ABC transporter G family member; Provisional

Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 47.92 E-value: 3.51e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   23 SFSPpaGQVTALIGPNGCGKSTLL-------------------------KAFARIltpqSGSLSLDGKGYSQLSARELAC 77
Cdd:PLN03140  902 AFRP--GVLTALMGVSGAGKTTLMdvlagrktggyiegdirisgfpkkqETFARI----SGYCEQNDIHSPQVTVRESLI 975

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   78 KVAFLPqvlpIPEGVNVRQLVAYgrsphnslwgrlsgadqhsVDQALQRMELATLAER-----PLSDLSGGQRQRAWLAM 152
Cdd:PLN03140  976 YSAFLR----LPKEVSKEEKMMF-------------------VDEVMELVELDNLKDAivglpGVTGLSTEQRKRLTIAV 1032

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462  153 ILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLH----DINQAcryADHLAVMQ-GGRLVTCGAPG 224
Cdd:PLN03140 1033 ELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHqpsiDIFEA---FDELLLMKrGGQVIYSGPLG 1106

PLN03130

ABC transporter C family member; Provisional

21-201

4.34e-06

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 47.81 E-value: 4.34e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   21 DLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQS-GSLSLDGKgysqlsarelackVAFLPQVLPIPEGvNVRQLVA 99
Cdd:PLN03130  635 NINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPPRSdASVVIRGT-------------VAYVPQVSWIFNA-TVRDNIL 700

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  100 YGrSPHNSlwGRLSGA-DQHSVDQALQRM---ELATLAERPLsDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD--IS 173
Cdd:PLN03130  701 FG-SPFDP--ERYERAiDVTALQHDLDLLpggDLTEIGERGV-NISGGQKQRVSMARAVYSNSDVYIFDDPLSALDahVG 776

                         170       180       190
                  ....*....|....*....|....*....|.
gi 492172462  174 HQVELLDLMRELSaeGKTVITV---LHDINQ 201
Cdd:PLN03130  777 RQVFDKCIKDELR--GKTRVLVtnqLHFLSQ 805

PRK00635

excinuclease ABC subunit A; Provisional

134-227

5.15e-06

excinuclease ABC subunit A; Provisional

Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 47.52 E-value: 5.15e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  134 ERPLSDLSGGQRQRAWLAMILAQDAAIV--LLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDiNQACRYADHL-- 209
Cdd:PRK00635  471 ERALATLSGGEQERTALAKHLGAELIGItyILDEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVEHD-EQMISLADRIid 549

                          90       100
                  ....*....|....*....|..
gi 492172462  210 ----AVMQGGRLVTCGAPGDVL 227
Cdd:PRK00635  550 igpgAGIFGGEVLFNGSPREFL 571

PRK03918

DNA double-strand break repair ATPase Rad50;

133-198

5.54e-06

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 47.37 E-value: 5.54e-06

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492172462 133 AERPLSDLSGGQRQ------RAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHD 198
Cdd:PRK03918 782 KERPLTFLSGGERIalglafRLALSLYLAGNIPLLILDEPTPFLDEERRRKLVDIMERYLRKIPQVIIVSHD 853

AAA_23

pfam13476

AAA domain;

20-68

7.12e-06

AAA domain;

Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 45.56 E-value: 7.12e-06

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 492172462   20 QDLSFSPPagqVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYS 68
Cdd:pfam13476  12 QTIDFSKG---LTLITGPNGSGKTTILDAIKLALYGKTSRLKRKSGGGF 57

uvrA

PRK00349

excinuclease ABC subunit UvrA;

131-230

7.69e-06

excinuclease ABC subunit UvrA;

Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 46.99 E-value: 7.69e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 131 TLAeRPLSDLSGGQRQRAWLAmilAQdaaI------VL--LDEPTTYLdisHQ------VELLDLMRELsaeGKTVITVL 196
Cdd:PRK00349 482 TLS-RSAGTLSGGEAQRIRLA---TQ---IgsgltgVLyvLDEPSIGL---HQrdndrlIETLKHLRDL---GNTLIVVE 548

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 492172462 197 HDiNQACRYADHL------AVMQGGRLVTCGAPGDVLTAE 230
Cdd:PRK00349 549 HD-EDTIRAADYIvdigpgAGVHGGEVVASGTPEEIMKNP 587

PRK00635

excinuclease ABC subunit A; Provisional

81-217

8.38e-06

excinuclease ABC subunit A; Provisional

Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 46.75 E-value: 8.38e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462   81 FLPQVLPIP-EGVNVRQLVAYGRSPHNSLWgrLSGADQHSVDQALQRMELATLA-ERPLSDLSGGQRQRAWLAMIL---A 155
Cdd:PRK00635  751 FLPQVLEVRyKGKNIADILEMTAYEAEKFF--LDEPSIHEKIHALCSLGLDYLPlGRPLSSLSGGEIQRLKLAYELlapS 828

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462  156 QDAAIVLLDEPTTYLDiSHQVE-LLDLMRELSAEGKTVITVLHDINqACRYADHLAVM--QGGRL 217
Cdd:PRK00635  829 KKPTLYVLDEPTTGLH-THDIKaLIYVLQSLTHQGHTVVIIEHNMH-VVKVADYVLELgpEGGNL 891

PRK00635

excinuclease ABC subunit A; Provisional

137-230

9.76e-06

excinuclease ABC subunit A; Provisional

Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 46.75 E-value: 9.76e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  137 LSDLSGGQRQRAWLAMIL---AQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHDInQACRYADHLAVM- 212
Cdd:PRK00635 1697 LSSLSLSEKIAIKIAKFLylpPKHPTLFLLDEIATSLDNQQKSALLVQLRTLVSLGHSVIYIDHDP-ALLKQADYLIEMg 1775

                          90       100
                  ....*....|....*....|...
gi 492172462  213 -----QGGRLVTCGAPGDVLTAE 230
Cdd:PRK00635 1776 pgsgkTGGKILFSGPPKDISASK 1798

UvrA

COG0178

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];

131-230

2.47e-05

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];

Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 45.40 E-value: 2.47e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 131 TLAeRPLSDLSGGQRQRAWLAmilaqdAAI------VL--LDEPTTYLdisHQ---VELLDLMRELSAEGKTVITVLHDi 199
Cdd:COG0178  478 TLD-RSAGTLSGGEAQRIRLA------TQIgsglvgVLyvLDEPSIGL---HQrdnDRLIETLKRLRDLGNTVIVVEHD- 546

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 492172462 200 NQACRYADHL------AVMQGGRLVTCGAPGDVLTAE 230
Cdd:COG0178  547 EDTIRAADYIidigpgAGEHGGEVVAQGTPEEILKNP 583

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

119-171

3.36e-05

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 44.79 E-value: 3.36e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 492172462  119 SVDQALQRMELATLAERPL---SDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:TIGR03269 145 AVGRAVDLIEMVQLSHRIThiaRDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLD 200

ABC_sbcCD

cd03279

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...

12-198

3.60e-05

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.

Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 43.80 E-value: 3.60e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  12 GYGATRIVQDLSFSPPAGQVTALI-GPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFLPQvlpipe 90
Cdd:cd03279   10 NFGPFREEQVIDFTGLDNNGLFLIcGPTGAGKSTILDAITYALYGKTPRYGRQENLRSVFAPGEDTAEVSFTFQ------ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  91 gvnvrqlvaygRSPHNSLWGRLSGADQHSVDQA--LQRMELATLAERPLSDLSGGQRQRAWLAM------ILAQDAAIVL 162
Cdd:cd03279   84 -----------LGGKKYRVERSRGLDYDQFTRIvlLPQGEFDRFLARPVSTLSGGETFLASLSLalalseVLQNRGGARL 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 492172462 163 ----LDEPTTYLDISHQVELLDLMRELSAEGKTVITVLHD 198
Cdd:cd03279  153 ealfIDEGFGTLDPEALEAVATALELIRTENRMVGVISHV 192

AAA_29

pfam13555

P-loop containing region of AAA domain;

20-57

4.24e-05

P-loop containing region of AAA domain;

Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 40.28 E-value: 4.24e-05

                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 492172462   20 QDLSFSPpaGQVTALIGPNGCGKSTLLKAFARILTPQS 57
Cdd:pfam13555  15 HTIPIDP--RGNTLLTGPSGSGKSTLLDAIQTLLVPAK 50

AAA_21

pfam13304

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...

134-193

7.79e-05

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.

Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 43.15 E-value: 7.79e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492172462  134 ERPLSDLSGGQRQraWLAMILA-----QDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVI 193
Cdd:pfam13304 231 ELPAFELSDGTKR--LLALLAAllsalPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLI 293

AAA_21

pfam13304

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...

31-65

9.52e-05

Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 42.76 E-value: 9.52e-05

                          10        20        30
                  ....*....|....*....|....*....|....*
gi 492172462   31 VTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGK 65
Cdd:pfam13304   1 INVLIGPNGSGKSNLLEALRFLADFDALVIGLTDE 35

SbcC

COG0419

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];

20-199

1.22e-04

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];

Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 41.92 E-value: 1.22e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  20 QDLSFSPPagqVTALIGPNGCGKSTLLKAFARILTPQSGSLSLDGKGYSQLSARELACKVAFL----PQVLPIPEGvNVR 95
Cdd:COG0419   17 ETIDFDDG---LNLIVGPNGAGKSTILEAIRYALYGKARSRSKLRSDLINVGSEEASVELEFEhggkRYRIERRQG-EFA 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  96 QLVAYGRSPHNSLWGRLSGAD------------QHSVDQALQRMELATLAER----------PLSDLSGGQRQRAWLAMI 153
Cdd:COG0419   93 EFLEAKPSERKEALKRLLGLEiyeelkerlkelEEALESALEELAELQKLKQeilaqlsgldPIETLSGGERLRLALADL 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 492172462 154 LAqdaaiVLLDepTTYLDISHQVELLDLMRELSaegktVITvlHDI 199
Cdd:COG0419  173 LS-----LILD--FGSLDEERLERLLDALEELA-----IIT--HVI 204

PTZ00265

multidrug resistance protein (mdr1); Provisional

140-199

1.88e-04

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 42.71 E-value: 1.88e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492172462  140 LSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEG-KTVITVLHDI 199
Cdd:PTZ00265 1359 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKAdKTIITIAHRI 1419

COG4637

Predicted ATPase [General function prediction only];

29-50

2.05e-04

Predicted ATPase [General function prediction only];

Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 42.23 E-value: 2.05e-04

                         10        20
                 ....*....|....*....|..
gi 492172462  29 GQVTALIGPNGCGKSTLLKAFA 50
Cdd:COG4637   21 GPLTVLIGANGSGKSNLLDALR 42

uvrA

PRK00349

excinuclease ABC subunit UvrA;

140-226

2.25e-04

excinuclease ABC subunit UvrA;

Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 42.37 E-value: 2.25e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 140 LSGGQRQRAWLAMILAQDA---AIVLLDEPTTYL---DISHqveLLDLMRELSAEGKTVITVLH--DInqaCRYADHLAV 211
Cdd:PRK00349 831 LSGGEAQRVKLAKELSKRStgkTLYILDEPTTGLhfeDIRK---LLEVLHRLVDKGNTVVVIEHnlDV---IKTADWIID 904

                         90       100
                 ....*....|....*....|.
gi 492172462 212 M------QGGRLVTCGAPGDV 226
Cdd:PRK00349 905 LgpeggdGGGEIVATGTPEEV 925

GguA

NF040905

sugar ABC transporter ATP-binding protein;

140-193

4.78e-04

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 40.93 E-value: 4.78e-04

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 492172462 140 LSGGQRQRAWLAMILAQDAAIVLLDEPTTYLDISHQVELLDLMRELSAEGKTVI 193
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVI 458

PRK02224

DNA double-strand break repair Rad50 ATPase;

140-209

5.37e-04

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.18 E-value: 5.37e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462 140 LSGGQRQ------RAWLAMILAQ----DAAI--VLLDEPTTYLD---ISHQVELLDLMRELSAEgkTVITVLHDiNQACR 204
Cdd:PRK02224 782 LSGGERAlfnlslRCAIYRLLAEgiegDAPLppLILDEPTVFLDsghVSQLVDLVESMRRLGVE--QIVVVSHD-DELVG 858


                 ....*
gi 492172462 205 YADHL 209
Cdd:PRK02224 859 AADDL 863

COG1106

ATPase/GTPase, AAA15 family [General function prediction only];

20-50

6.32e-04

ATPase/GTPase, AAA15 family [General function prediction only];

Pssm-ID: 440723 [Multi-domain] Cd Length: 330 Bit Score: 40.41 E-value: 6.32e-04

                         10        20        30
                 ....*....|....*....|....*....|....
gi 492172462  20 QDLSFSPPA---GQVTALIGPNGCGKSTLLKAFA 50
Cdd:COG1106   17 LTLSMVASGlrlLRVNLIYGANASGKSNLLEALY 50

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

26-55

1.62e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 39.51 E-value: 1.62e-03

                          10        20        30
                  ....*....|....*....|....*....|
gi 492172462   26 PPAGQVTALIGPNGCGKSTLLKAFARILTP 55
Cdd:COG4913    21 DFDGRGTLLTGDNGSGKSTLLDAIQTLLVP 50

PRK13541

cytochrome c biogenesis protein CcmA; Provisional

17-171

1.69e-03

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 38.70 E-value: 1.69e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492172462  17 RIVQDLSFSPPAGQVTALIGPNGCGKSTLLKAFARILTPQSGSLSldgkgYSQLSARELA---CkvAFLPQVLPIPEGVN 93
Cdd:PRK13541  14 KNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIY-----YKNCNINNIAkpyC--TYIGHNLGLKLEMT 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492172462  94 VRQLVAYGRSPHNSLwgrlsgadqHSVDQALQRMELATLAERPLSDLSGGQRQRAWLAMILAQDAAIVLLDEPTTYLD 171
Cdd:PRK13541  87 VFENLKFWSEIYNSA---------ETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLS 155

AAA_15

pfam13175

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...

30-49

4.32e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.

Pssm-ID: 433011 [Multi-domain] Cd Length: 392 Bit Score: 37.96 E-value: 4.32e-03

                          10        20
                  ....*....|....*....|
gi 492172462   30 QVTALIGPNGCGKSTLLKAF 49
Cdd:pfam13175  24 DLTVLIGKNNSGKSSILEAL 43

ABC_SMC2_euk

cd03273

ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of ...

137-174

6.62e-03

ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).

Pssm-ID: 213240 [Multi-domain] Cd Length: 251 Bit Score: 36.89 E-value: 6.62e-03

                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 492172462 137 LSDLSGGQRQRAWLAMILA----QDAAIVLLDEPTTYLDISH 174
Cdd:cd03273  164 LTELSGGQRSLVALSLILAlllfKPAPMYILDEVDAALDLSH 205

PLN03073

ABC transporter F family; Provisional

141-197

6.90e-03

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 37.53 E-value: 6.90e-03

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 492172462 141 SGGQRQRAWLAMILAQDAAIVLLDEPTTYLDIsHQVelLDLMRELSAEGKTVITVLH 197
Cdd:PLN03073 346 SGGWRMRIALARALFIEPDLLLLDEPTNHLDL-HAV--LWLETYLLKWPKTFIVVSH 399

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01