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Conserved domains on  [gi|492337508|ref|WP_005814138|]
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MULTISPECIES: right-handed parallel beta-helix repeat-containing protein [Bacteroides]

Protein Classification

right-handed parallel beta-helix repeat-containing protein( domain architecture ID 12131601)

right-handed parallel beta-helix repeat-containing protein that may share some similarity with pectate lyases, similar to Bacteroides thetaiotaomicron alpha-1,3-galactosidase B that removes both branched alpha-1,3-linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures

PubMed:  38767844

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 423-581 3.85e-05

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


:

Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 44.32  E-value: 3.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  423 EVEIRNSYFTRTSTRGTLVTTPRKVVIENNTYYKTGMSAILIEADAEGWyesgpvkdvlIKGNTFIDCAYNGG---PGHA 499
Cdd:pfam13229  10 NATIKNNTISNNGGYGIYLRGSSNATIENNTITNNGGDGIEISGSSNNT----------ISNNTISNNGGGGIalrGSSN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  500 VIAIhpSNKIIDAERP-----VHQNIRIEDNTFR-TFDYPVLYAKSTAGLLFRNNTIVrtetfpaasGNPY--VFYLNGC 571
Cdd:pfam13229  80 NLIE--NNTISNNGGAgiylsDSSNNTIENNIIHnNGGSGIVIEDSSNNVTISNNTVT---------NNKGagILIVGGS 148

                         170
                  ....*....|
gi 492337508  572 KKAVIEGTVF 581
Cdd:pfam13229 149 SNNTVENNTF 158
Pgu1 super family cl35001
Polygalacturonase [Carbohydrate transport and metabolism];
22-140 1.32e-03

Polygalacturonase [Carbohydrate transport and metabolism];


The actual alignment was detected with superfamily member COG5434:

Pssm-ID: 444185 [Multi-domain]  Cd Length: 373  Bit Score: 41.34  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  22 QKDTVYVTDFGALPYSYENCVTQIQAAIDECKRTGAKVLSLPEGRY---------DIW---PEGAT------RKEYYISN 83
Cdd:COG5434    6 PAKTFNITDFGAKGDGKTLNTAAIQKAIDACAAAGGGTVLVPAGTYltgpiflksNVTlhlEKGATllgstdPADYPLVE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  84 TSTEqecpskvktvGLMLH---------EIDDL------TIEGNGATLMYHGKMTT-----------------IALEHCD 131
Cdd:COG5434   86 TRWE----------GGELKgysaliyaeNAENIaitgegTIDGNGDAWWPWKKEARqsgwvpvgaydylrprlIQLKNCK 155


                 ....*....
gi 492337508 132 GVRINNLHI 140
Cdd:COG5434  156 NVLLEGVTL 164
 
Name Accession Description Interval E-value
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 423-581 3.85e-05

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 44.32  E-value: 3.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  423 EVEIRNSYFTRTSTRGTLVTTPRKVVIENNTYYKTGMSAILIEADAEGWyesgpvkdvlIKGNTFIDCAYNGG---PGHA 499
Cdd:pfam13229  10 NATIKNNTISNNGGYGIYLRGSSNATIENNTITNNGGDGIEISGSSNNT----------ISNNTISNNGGGGIalrGSSN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  500 VIAIhpSNKIIDAERP-----VHQNIRIEDNTFR-TFDYPVLYAKSTAGLLFRNNTIVrtetfpaasGNPY--VFYLNGC 571
Cdd:pfam13229  80 NLIE--NNTISNNGGAgiylsDSSNNTIENNIIHnNGGSGIVIEDSSNNVTISNNTVT---------NNKGagILIVGGS 148

                         170
                  ....*....|
gi 492337508  572 KKAVIEGTVF 581
Cdd:pfam13229 149 SNNTVENNTF 158
Pgu1 COG5434
Polygalacturonase [Carbohydrate transport and metabolism];
22-140 1.32e-03

Polygalacturonase [Carbohydrate transport and metabolism];


Pssm-ID: 444185 [Multi-domain]  Cd Length: 373  Bit Score: 41.34  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  22 QKDTVYVTDFGALPYSYENCVTQIQAAIDECKRTGAKVLSLPEGRY---------DIW---PEGAT------RKEYYISN 83
Cdd:COG5434    6 PAKTFNITDFGAKGDGKTLNTAAIQKAIDACAAAGGGTVLVPAGTYltgpiflksNVTlhlEKGATllgstdPADYPLVE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  84 TSTEqecpskvktvGLMLH---------EIDDL------TIEGNGATLMYHGKMTT-----------------IALEHCD 131
Cdd:COG5434   86 TRWE----------GGELKgysaliyaeNAENIaitgegTIDGNGDAWWPWKKEARqsgwvpvgaydylrprlIQLKNCK 155


                 ....*....
gi 492337508 132 GVRINNLHI 140
Cdd:COG5434  156 NVLLEGVTL 164
 
Name Accession Description Interval E-value
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 423-581 3.85e-05

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 44.32  E-value: 3.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  423 EVEIRNSYFTRTSTRGTLVTTPRKVVIENNTYYKTGMSAILIEADAEGWyesgpvkdvlIKGNTFIDCAYNGG---PGHA 499
Cdd:pfam13229  10 NATIKNNTISNNGGYGIYLRGSSNATIENNTITNNGGDGIEISGSSNNT----------ISNNTISNNGGGGIalrGSSN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  500 VIAIhpSNKIIDAERP-----VHQNIRIEDNTFR-TFDYPVLYAKSTAGLLFRNNTIVrtetfpaasGNPY--VFYLNGC 571
Cdd:pfam13229  80 NLIE--NNTISNNGGAgiylsDSSNNTIENNIIHnNGGSGIVIEDSSNNVTISNNTVT---------NNKGagILIVGGS 148

                         170
                  ....*....|
gi 492337508  572 KKAVIEGTVF 581
Cdd:pfam13229 149 SNNTVENNTF 158
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 418-550 5.22e-05

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 43.93  E-value: 5.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  418 MTCTPEVEIRNSYFTRTSTRGTLVTTPRKVVIENNTYYKTGMSAILIEAdaegwyesgpVKDVLIKGNTFIDCAYNGgpg 497
Cdd:pfam13229  51 ISGSSNNTISNNTISNNGGGGIALRGSSNNLIENNTISNNGGAGIYLSD----------SSNNTIENNIIHNNGGSG--- 117

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 492337508  498 havIAIHPSNKiidaerpvhqNIRIEDNTF-RTFDYPVLYAKSTAGLLFRNNTI 550
Cdd:pfam13229 118 ---IVIEDSSN----------NVTISNNTVtNNKGAGILIVGGSSNNTVENNTF 158
Pgu1 COG5434
Polygalacturonase [Carbohydrate transport and metabolism];
22-140 1.32e-03

Polygalacturonase [Carbohydrate transport and metabolism];


Pssm-ID: 444185 [Multi-domain]  Cd Length: 373  Bit Score: 41.34  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  22 QKDTVYVTDFGALPYSYENCVTQIQAAIDECKRTGAKVLSLPEGRY---------DIW---PEGAT------RKEYYISN 83
Cdd:COG5434    6 PAKTFNITDFGAKGDGKTLNTAAIQKAIDACAAAGGGTVLVPAGTYltgpiflksNVTlhlEKGATllgstdPADYPLVE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492337508  84 TSTEqecpskvktvGLMLH---------EIDDL------TIEGNGATLMYHGKMTT-----------------IALEHCD 131
Cdd:COG5434   86 TRWE----------GGELKgysaliyaeNAENIaitgegTIDGNGDAWWPWKKEARqsgwvpvgaydylrprlIQLKNCK 155


                 ....*....
gi 492337508 132 GVRINNLHI 140
Cdd:COG5434  156 NVLLEGVTL 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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