|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
40-1068 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 646.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 40 KKITGKVLDAAGEPIIGASVLVKGSGTGAVTDIDGNFSVEAPVGSTLEVSFIGYKTVTLKVTNATTYTVSLQDDSQALDE 119
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 120 VVVTAMGIKKeRKALGYSMEDVKSDELMKMKTANPISSLSGKVAGVNVTQSSGAAGAGAQIILRGGTSgaEGKDNQPLFV 199
Cdd:TIGR04056 81 VVVVGYGTQK-KKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISS--FGGNNSPLYV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 200 VDGVIFDNSssvvgnsafdgsmrsasttsnrLMDINPEDIESMSVLKGPAAAALYGSRAANGVILITTKKGKEGVVEVNI 279
Cdd:TIGR04056 158 IDGVPRDNG----------------------LSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISY 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 280 NSKFTASWVKSLPQTQRQYarGYMEDQYDSKKNYtgtvfNDFAYTSWGEKSNAATYDNIGD------------FFQGGNI 347
Cdd:TIGR04056 216 NAEFGFSTPTRLPEMLNAY--EYAELYNEALLNR-----GSSPPDIYTDEEIEAYRNGLDPdlypntdwqdeiFKRTAFN 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 348 FDESASVAGGTKNSKFYLSGSYYDQVGVVPETGYKKYAFRFNGEQKV-GIFTFNASAAYSdaHTDRTLTGAGlyNSSGNG 426
Cdd:TIGR04056 289 QRHNLSVSGGTEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAKLtKTLKLSLNVSGS--LSKYNNPGGS--TSNIWG 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 427 ALYGVYNWSPFDRMTHYQNEDGTRYRlfgdrlDPWDERDNPYWIVNRNHMYDDIDRFNGMLSIKADIAKWWFVSYKIGID 506
Cdd:TIGR04056 365 ALMLFPRGTPYSTPPVYSDGYYPAYN------SGNTSLQNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYD 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 507 RYTQTASNRLAANGVLKQVW--QKGMMSDNTQQFRYMSHDFMSNMSHKFGDFDLNLLLGATMDETKTDRSSMMAwnfsvp 584
Cdd:TIGR04056 439 YSNYKNKKYYKNPYYYNATGgaNNGYYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQENKSSSYGGLL------ 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 585 DFFSYANASKDNKQFTHAATKKRLVGAFGEFRASWKNMLYLTVSGRNDWTSTLPLENRSYFYPSVSGSFVFTEalqrLGW 664
Cdd:TIGR04056 513 DDLPSLDAGTSDASVSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISE----EKF 588
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 665 LDD--SVLNFGKLRASWAKVGKD--------TGVYELETALWPTGTYlDGTVGVGNTWTR-GNDKLKPEMTKSTEIGVEL 733
Cdd:TIGR04056 589 MKKlkKWLSFLKLRASYGIVGNDnigdrypyLSLYNLGDGGYNFGTN-NGTSVTGITESRyGNPNLKWEKTKKWNLGLDL 667
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 734 SFFKNRLHIDYAYYTNDSYNQILAPRGPQSTGYIFWSINAGNVYNKGMELSISGTPIQTKDWTWDIGLNMAGNRGTLDGL 813
Cdd:TIGR04056 668 GFFNNRLSLTVDYYYKKTKDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILEL 747
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 814 PEGMGVMYVTDVQY-AGMQAASFSGGDFMGIagtkWKRND----------AGEVIL-DKNG---MPTYDKtlVAVGNRES 878
Cdd:TIGR04056 748 DEGAYLPVKYPYISkEGGPIGQIYGYIADGL----FKDDDspkqtfgnvrPGDIKYkDVNGdgkIDDDDR--VPIGYSNT 821
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 879 -SFTGGLNNTLTWKNFTFNMLWEFRVGGDVVNGTQYAMDNSGVSqfsadvrNRSLTVTGVNangdpvtNTWEADKTYT-F 956
Cdd:TIGR04056 822 pDLTYGFGNSFSYKGFDLSALFQGSGGGDVFNDGRGFYPFNGGD-------WGNVLKIVAD-------NRWTPENPNAdY 887
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 957 NGVQMSGYNIIKDYYQNYYSKESANYitdvnsLRLRSVSLSYEFPKTWLSKIGFvKRASVSVAATNLLLITNYDG-DPEv 1035
Cdd:TIGR04056 888 PRLSYGDSNNSNNYQASTRWLEDGSY------LRLKNLTLGYTLPKKWLKKIGI-SNLRVYFSGQNLFTFSKYKGwDPE- 959
|
1050 1060 1070
....*....|....*....|....*....|...
gi 492382541 1036 aaagagvggssSVGFDYCGVPATSTMSFGLNLT 1068
Cdd:TIGR04056 960 -----------LQGNDGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
117-816 |
1.18e-39 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 157.30 E-value: 1.18e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 117 LDEVVVTAMGIKKERKALGYSMEDVKSDELMKMKTANPISSLsGKVAGVNVTQSSGAAGagaQIILRGGTSGaegkDNQP 196
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAGGGAG---QISIRGFGGG----GNRV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 197 LFVVDGVifdnsssvvgnsafdgSMRSASTTSNRLMDINPEDIESMSVLKGPAAAaLYGSRAANGVILITTKKGKEGvve 276
Cdd:COG1629 73 LVLVDGV----------------PLNDPSGGDGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDG--- 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 277 vninskftaswvkslpqtqrqyargymedqydskknYTGTVfndfaytswgeksnAATYDNIGDFfqggnifDESASVAG 356
Cdd:COG1629 133 ------------------------------------KGGEV--------------SASYGSYGTY-------RASLSLSG 155
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 357 GTKNSKFYLSGSYYDQVGVVPETGYKKYAFRFNGEQKVG---IFTFNASAAYSDAHTDRTLTGAGLYNSSGNGALYGVYN 433
Cdd:COG1629 156 GNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGddtRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDGTNPYS 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 434 WSPFDRMTHyqnedgtRYRLFGDrldpwderdnpywivnrnhmyddIDRFNGMLSIKADiakwwfVSYKIGIDRYTQTAS 513
Cdd:COG1629 236 NDTDDNTRD-------RYSLSLE-----------------------YEHLGDGLKLSAS------AYYRYDDTDLDSDFT 279
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 514 NRLAANGVLkqvwqkgmmSDNTQQFRYMSHDFMSNMSHKFGDfDLNLLLGATMDETKTDRSSmmawnfsvPDFFSYANAS 593
Cdd:COG1629 280 PTPADGGTL---------EQTDFDNRTYGLELRLTYDLGFGG-KHTLLVGLDYQRQDLDGSG--------YPLDLGSGSL 341
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 594 KDNKQFTHAATKKRLVGAFGEFRASWKNMLYLTVSGRNDWTS----------TLPLENRSY--FYPSVSGSFVFTEALQr 661
Cdd:COG1629 342 PTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSydvddtvtgtDSASGSRSYsaFSPSLGLTYQLSPNLS- 420
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 662 lgwlddsvlnfgkLRASWAKVGKdtgvyeletalwpTGTYLDGTVGVGNTWTRGNDKLKPEMTKSTEIGVELSFFKNRLH 741
Cdd:COG1629 421 -------------LYASYSRGFR-------------APTFGELYANGTDPYSVGNPDLKPETSTNYELGLRYRLLDGRLS 474
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492382541 742 IDYAYYTNDSYNQILAPRGPQSTGYIFWSINAGNVYNKGMELSISGTPIQtkdwTWDIGLNMAGNRGTLDGLPEG 816
Cdd:COG1629 475 LSLALFYSDVDNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTP----GLSLNASYSYTDAKFDDDTDG 545
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
42-122 |
5.14e-21 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 88.42 E-value: 5.14e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 42 ITGKVLDAA-GEPIIGASVLVKGSGTGAVTDIDGNFSVEA-PVGS-TLEVSFIGYKTVTLKVT----NATTYTVSLQDDS 114
Cdd:pfam13715 1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKNlPAGTyTLVVSFVGYKTQEKKVTvsndNTLDVNFLLKEDA 80
|
....*...
gi 492382541 115 QALDEVVV 122
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
140-801 |
4.01e-19 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 92.90 E-value: 4.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 140 DVKSDELMKMKTANPISSLSGKVAGVNVTQSSGaaGAGAQIILRGGTSgaegkdNQPLFVVDGVIfdnsssvvGNSAFDG 219
Cdd:cd01347 3 SVITAEDIEKQPATSLADLLRRIPGVSVTRGGG--GGGSTISIRGFGP------DRTLVLVDGLP--------LASSNYG 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 220 SMRSASTtsnrlmdINPEDIESMSVLKGPAAAaLYGSRAANGVILITTKKGKEgvvevninsKFTASWvkSLpqtqrqya 299
Cdd:cd01347 67 RGVDLNT-------IPPELIERVEVLKGPSSA-LYGSGAIGGVVNIITKRPTD---------EFGGSV--TA-------- 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 300 rGYMEDQYDSKKNYTGTVFNDFAYTSWGEKSNAATYDNIGDFFQGGNIFDESasvagGTKNSKFYLSGSYydqvgvvpet 379
Cdd:cd01347 120 -GYGSDNSGSSGGGGFDVSGALADDGAFGARLYGAYRDGDGTIDGDGQADDS-----DEERYNVAGKLDW---------- 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 380 gykkyafRFNGEQkvgifTFNASAAYSDAHTDRTltgAGLYNSSGNGALYGVYNWSPFDRMTHYQNEDGTRYRlfgdrld 459
Cdd:cd01347 184 -------RPDDDT-----RLTLDAGYQDQDADGP---GGTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKR------- 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 460 pwderdnpywivnrNHMYDDIDRFNGMLSIKADiakwwfVSYkigidRYTQTASNRLAANGVLKQVWQKGMMSDNTQQFR 539
Cdd:cd01347 242 --------------ASLGLEHDLNDTGWTLRAN------LSY-----SYTDNDGDPLILNGGNNAAGGDLGRSGYSSERD 296
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 540 YMSHDFMSNMSHKFGDF--DLNLLLGAtmdetktdrssmmawnfsvpdffSYANASKDNKQFthaatkkrlvGAFGEFRA 617
Cdd:cd01347 297 TTQLGFDAGLNAPFGTGpvAHTLTLGV-----------------------EYRREELDEKQT----------ALYAQDTI 343
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 618 SWKNMLYLTVSGRNDWTSTLPLEN----------RSYFYPSVSGSFVFTEALQrlgwlddsvlnfgkLRASWAKVgkdtg 687
Cdd:cd01347 344 ELTDDLTLTLGLRYDHYDQDSKDTiaggttakksYSHWSPSLGLVYKLTDGLS--------------LYASYSQG----- 404
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 688 vYELetalwPTGTYLDGTVGVGNTWTRGNDKLKPEMTKSTEIGVELSFFKnRLHIDYAYYTNDSYNQILAPRGPQSTGYI 767
Cdd:cd01347 405 -FRA-----PSLGELYGGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGD-GLTLSAALFRIDIKNEIVSTPTNTGLGLV 477
|
650 660 670
....*....|....*....|....*....|....
gi 492382541 768 FWSINAGNVYNKGMELSISGTPiqTKDWTWDIGL 801
Cdd:cd01347 478 TVYVNGGKARIRGVELEASYDL--TDGLGLTGSY 509
|
|
| PRK13524 |
PRK13524 |
FepA family TonB-dependent siderophore receptor; |
101-270 |
3.96e-11 |
|
FepA family TonB-dependent siderophore receptor;
Pssm-ID: 237410 [Multi-domain] Cd Length: 744 Bit Score: 67.36 E-value: 3.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 101 TNATTYTVSLQDDSQALDEVVVTAMgiKKERKALGYSMedVKSDELMKMKTANPISSLSGKVAGVNVT--QSSGAAGAGA 178
Cdd:PRK13524 22 AAEAEDAKTDDTPASHEDTIVVTAA--EQNLQAPGVST--ITAEDIRKRPPANDVSEIIRTMPGVNLTgnSTSGQRGNNR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 179 QIILRGgtsgaEGKDNQpLFVVDGvifdnsssvvgnsafdgsMRSASTTSNRLM---------DIN---PEDIESMSVLK 246
Cdd:PRK13524 98 QIDIRG-----MGPENT-LILIDG------------------KPVSSRNSVRYGwrgerdtrgDTNwvpPEMIERIEVLR 153
|
170 180
....*....|....*....|....
gi 492382541 247 GPAAAAlYGSRAANGVILITTKKG 270
Cdd:PRK13524 154 GPAAAR-YGNGAAGGVVNIITKKP 176
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
40-1068 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 646.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 40 KKITGKVLDAAGEPIIGASVLVKGSGTGAVTDIDGNFSVEAPVGSTLEVSFIGYKTVTLKVTNATTYTVSLQDDSQALDE 119
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 120 VVVTAMGIKKeRKALGYSMEDVKSDELMKMKTANPISSLSGKVAGVNVTQSSGAAGAGAQIILRGGTSgaEGKDNQPLFV 199
Cdd:TIGR04056 81 VVVVGYGTQK-KKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISS--FGGNNSPLYV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 200 VDGVIFDNSssvvgnsafdgsmrsasttsnrLMDINPEDIESMSVLKGPAAAALYGSRAANGVILITTKKGKEGVVEVNI 279
Cdd:TIGR04056 158 IDGVPRDNG----------------------LSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISY 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 280 NSKFTASWVKSLPQTQRQYarGYMEDQYDSKKNYtgtvfNDFAYTSWGEKSNAATYDNIGD------------FFQGGNI 347
Cdd:TIGR04056 216 NAEFGFSTPTRLPEMLNAY--EYAELYNEALLNR-----GSSPPDIYTDEEIEAYRNGLDPdlypntdwqdeiFKRTAFN 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 348 FDESASVAGGTKNSKFYLSGSYYDQVGVVPETGYKKYAFRFNGEQKV-GIFTFNASAAYSdaHTDRTLTGAGlyNSSGNG 426
Cdd:TIGR04056 289 QRHNLSVSGGTEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAKLtKTLKLSLNVSGS--LSKYNNPGGS--TSNIWG 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 427 ALYGVYNWSPFDRMTHYQNEDGTRYRlfgdrlDPWDERDNPYWIVNRNHMYDDIDRFNGMLSIKADIAKWWFVSYKIGID 506
Cdd:TIGR04056 365 ALMLFPRGTPYSTPPVYSDGYYPAYN------SGNTSLQNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYD 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 507 RYTQTASNRLAANGVLKQVW--QKGMMSDNTQQFRYMSHDFMSNMSHKFGDFDLNLLLGATMDETKTDRSSMMAwnfsvp 584
Cdd:TIGR04056 439 YSNYKNKKYYKNPYYYNATGgaNNGYYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQENKSSSYGGLL------ 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 585 DFFSYANASKDNKQFTHAATKKRLVGAFGEFRASWKNMLYLTVSGRNDWTSTLPLENRSYFYPSVSGSFVFTEalqrLGW 664
Cdd:TIGR04056 513 DDLPSLDAGTSDASVSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISE----EKF 588
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 665 LDD--SVLNFGKLRASWAKVGKD--------TGVYELETALWPTGTYlDGTVGVGNTWTR-GNDKLKPEMTKSTEIGVEL 733
Cdd:TIGR04056 589 MKKlkKWLSFLKLRASYGIVGNDnigdrypyLSLYNLGDGGYNFGTN-NGTSVTGITESRyGNPNLKWEKTKKWNLGLDL 667
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 734 SFFKNRLHIDYAYYTNDSYNQILAPRGPQSTGYIFWSINAGNVYNKGMELSISGTPIQTKDWTWDIGLNMAGNRGTLDGL 813
Cdd:TIGR04056 668 GFFNNRLSLTVDYYYKKTKDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILEL 747
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 814 PEGMGVMYVTDVQY-AGMQAASFSGGDFMGIagtkWKRND----------AGEVIL-DKNG---MPTYDKtlVAVGNRES 878
Cdd:TIGR04056 748 DEGAYLPVKYPYISkEGGPIGQIYGYIADGL----FKDDDspkqtfgnvrPGDIKYkDVNGdgkIDDDDR--VPIGYSNT 821
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 879 -SFTGGLNNTLTWKNFTFNMLWEFRVGGDVVNGTQYAMDNSGVSqfsadvrNRSLTVTGVNangdpvtNTWEADKTYT-F 956
Cdd:TIGR04056 822 pDLTYGFGNSFSYKGFDLSALFQGSGGGDVFNDGRGFYPFNGGD-------WGNVLKIVAD-------NRWTPENPNAdY 887
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 957 NGVQMSGYNIIKDYYQNYYSKESANYitdvnsLRLRSVSLSYEFPKTWLSKIGFvKRASVSVAATNLLLITNYDG-DPEv 1035
Cdd:TIGR04056 888 PRLSYGDSNNSNNYQASTRWLEDGSY------LRLKNLTLGYTLPKKWLKKIGI-SNLRVYFSGQNLFTFSKYKGwDPE- 959
|
1050 1060 1070
....*....|....*....|....*....|...
gi 492382541 1036 aaagagvggssSVGFDYCGVPATSTMSFGLNLT 1068
Cdd:TIGR04056 960 -----------LQGNDGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
117-816 |
1.18e-39 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 157.30 E-value: 1.18e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 117 LDEVVVTAMGIKKERKALGYSMEDVKSDELMKMKTANPISSLsGKVAGVNVTQSSGAAGagaQIILRGGTSGaegkDNQP 196
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAGGGAG---QISIRGFGGG----GNRV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 197 LFVVDGVifdnsssvvgnsafdgSMRSASTTSNRLMDINPEDIESMSVLKGPAAAaLYGSRAANGVILITTKKGKEGvve 276
Cdd:COG1629 73 LVLVDGV----------------PLNDPSGGDGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDG--- 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 277 vninskftaswvkslpqtqrqyargymedqydskknYTGTVfndfaytswgeksnAATYDNIGDFfqggnifDESASVAG 356
Cdd:COG1629 133 ------------------------------------KGGEV--------------SASYGSYGTY-------RASLSLSG 155
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 357 GTKNSKFYLSGSYYDQVGVVPETGYKKYAFRFNGEQKVG---IFTFNASAAYSDAHTDRTLTGAGLYNSSGNGALYGVYN 433
Cdd:COG1629 156 GNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGddtRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDGTNPYS 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 434 WSPFDRMTHyqnedgtRYRLFGDrldpwderdnpywivnrnhmyddIDRFNGMLSIKADiakwwfVSYKIGIDRYTQTAS 513
Cdd:COG1629 236 NDTDDNTRD-------RYSLSLE-----------------------YEHLGDGLKLSAS------AYYRYDDTDLDSDFT 279
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 514 NRLAANGVLkqvwqkgmmSDNTQQFRYMSHDFMSNMSHKFGDfDLNLLLGATMDETKTDRSSmmawnfsvPDFFSYANAS 593
Cdd:COG1629 280 PTPADGGTL---------EQTDFDNRTYGLELRLTYDLGFGG-KHTLLVGLDYQRQDLDGSG--------YPLDLGSGSL 341
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 594 KDNKQFTHAATKKRLVGAFGEFRASWKNMLYLTVSGRNDWTS----------TLPLENRSY--FYPSVSGSFVFTEALQr 661
Cdd:COG1629 342 PTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSydvddtvtgtDSASGSRSYsaFSPSLGLTYQLSPNLS- 420
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 662 lgwlddsvlnfgkLRASWAKVGKdtgvyeletalwpTGTYLDGTVGVGNTWTRGNDKLKPEMTKSTEIGVELSFFKNRLH 741
Cdd:COG1629 421 -------------LYASYSRGFR-------------APTFGELYANGTDPYSVGNPDLKPETSTNYELGLRYRLLDGRLS 474
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492382541 742 IDYAYYTNDSYNQILAPRGPQSTGYIFWSINAGNVYNKGMELSISGTPIQtkdwTWDIGLNMAGNRGTLDGLPEG 816
Cdd:COG1629 475 LSLALFYSDVDNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTP----GLSLNASYSYTDAKFDDDTDG 545
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
95-802 |
1.56e-38 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 153.09 E-value: 1.56e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 95 TVTLKVTNATTYTVSLQDDSQALDEVVVTAMGIKKERKALGYSMEDVKSDELMKMKTANPISSLSgKVAGVNVTQSSGAA 174
Cdd:COG4771 5 SLLLLLALAAQAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALR-LLPGVSVTRSGGRG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 175 GAGaQIILRGGTSgaegkdNQPLFVVDGVifdnsssVVGNSAFDGSMRsasttsnrLMDINPEDIESMSVLKGPAAAaLY 254
Cdd:COG4771 84 GSS-GISIRGLGG------DRVLVLIDGV-------PVNNPALGGGGD--------LSYIPPDDIERIEVIRGPASA-LY 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 255 GSRAANGVILITTKKGkegvvevninskftaswvkslpqtqrqyargymedqydsKKNYTGTVFNDFAYTSWGEKSNaat 334
Cdd:COG4771 141 GSDAIGGVINIITKKP---------------------------------------TDELEGSVSLGYGSNGNGTYSG--- 178
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 335 ydnigdffqggnifdeSASVAGGTKNSKFYLSGSYYDQvgvvpeTGYKKYafrfngeqkvgiftFNASAAYSDAHTDRTL 414
Cdd:COG4771 179 ----------------SLSLGGPGDKLSFLLSGSYRDR------DGYLDY--------------RNGGFVGNSGYERYNL 222
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 415 TGAGLYNSSGNGALYGVYNwspfdrmthYQNEDGTRyrlfgdrlDPWDERDNPYWIVNRNHMYDDIDRFNGMLSIKADIA 494
Cdd:COG4771 223 NAKLGYRLSDNHRLSLSGG---------YSRQDRDG--------GPPTLGDTEISSDNAGDRDTTTDRGNYSLRYNGDLG 285
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 495 KWWFVSYkiGIDRYTQTASNRLAANGvlkqvwqkgmmSDNTQQFRYMSHDFMSNMSHKFGDfDLNLLLGAtmdETKTDRs 574
Cdd:COG4771 286 DNLDLSL--YYSRTDRDSTNGSLGGS-----------TGSFSDSDDTTYGLELDLTYPLGG-NHTLTLGA---EYRYDD- 347
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 575 smmawnFSVPDFFSYANASKDNkqfthaatkkrlVGAFGEFRASWKNMLYLTVSGRNDWTSTLPLENRSYFYPSVSGSFV 654
Cdd:COG4771 348 ------LDSSSFLGGADASRDT------------YGLFAQDEWKLTDKLTLTAGLRYDYYSTFGASNYTAFSPRLGLRYD 409
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 655 FTEALqrlgwlddsvlnfgKLRASWAKVGKDTGVYELETALwptgtyldgtVGVGNTWTRGNDKLKPEMTKSTEIGVELS 734
Cdd:COG4771 410 LSDNL--------------TLRASYGRGFRAPSLAELYGSG----------TGTPGRYVLGNPDLKPETSDNYELGLEYR 465
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492382541 735 FFKNRLHIDYAYYTNDSYNQILAPRGPQSTGYIFWSINAGNVYNKGMELSISGTPiqTKDWTWDIGLN 802
Cdd:COG4771 466 LGNGGLSLSLTGFYTDIKDLIVLVPVGPGPGDVLQYENVGKARTYGLELELKYRL--GKGLTLTASYT 531
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
120-434 |
4.88e-32 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 126.53 E-value: 4.88e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 120 VVVTAMGIKKERKALGYSMEDVKSDELMKMKTANPISSLSgKVAGVNVtQSSGAAGAGAQIILRGGTSgaegkdNQPLFV 199
Cdd:COG4206 1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQV-SSSGGPGSAASISIRGLGS------NQTLVL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 200 VDGVIfdnsssvvgnsafdgsMRSASTTSNRLMDINPEDIESMSVLKGPAAAaLYGSRAANGVILITTKKGKEGV---VE 276
Cdd:COG4206 73 IDGVP----------------LNDPSLGGVDLSLIPPDDIERIEVLKGAASA-LYGSDAIGGVINITTKKGKKGFkgsVS 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 277 VNINSkftaswvkslpQTQRQYARGYMEDqydskknytgtvFNDFAYTSWGEKSNAATYDNIGDFFQGGNIFD-ESASVA 355
Cdd:COG4206 136 ASYGS-----------FGTRRLSASLSGG------------AGKFSYSLSASYRRSDGYRYNDPDLRNNDGYEnTSLNAR 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 356 GG---TKNSKFYLSGSYYDQVGVVPETGYKKYAFR--FNGEQKVGIFTFNASAAYSDAHTDRTLTGAGLYNSSGNGALYG 430
Cdd:COG4206 193 LGyklGDNGSLSLSGGYSDSERGYPGAVGSDRNLRlsLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARA 272
|
....
gi 492382541 431 VYNW 434
Cdd:COG4206 273 GLSY 276
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
42-122 |
5.14e-21 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 88.42 E-value: 5.14e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 42 ITGKVLDAA-GEPIIGASVLVKGSGTGAVTDIDGNFSVEA-PVGS-TLEVSFIGYKTVTLKVT----NATTYTVSLQDDS 114
Cdd:pfam13715 1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKNlPAGTyTLVVSFVGYKTQEKKVTvsndNTLDVNFLLKEDA 80
|
....*...
gi 492382541 115 QALDEVVV 122
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
140-801 |
4.01e-19 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 92.90 E-value: 4.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 140 DVKSDELMKMKTANPISSLSGKVAGVNVTQSSGaaGAGAQIILRGGTSgaegkdNQPLFVVDGVIfdnsssvvGNSAFDG 219
Cdd:cd01347 3 SVITAEDIEKQPATSLADLLRRIPGVSVTRGGG--GGGSTISIRGFGP------DRTLVLVDGLP--------LASSNYG 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 220 SMRSASTtsnrlmdINPEDIESMSVLKGPAAAaLYGSRAANGVILITTKKGKEgvvevninsKFTASWvkSLpqtqrqya 299
Cdd:cd01347 67 RGVDLNT-------IPPELIERVEVLKGPSSA-LYGSGAIGGVVNIITKRPTD---------EFGGSV--TA-------- 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 300 rGYMEDQYDSKKNYTGTVFNDFAYTSWGEKSNAATYDNIGDFFQGGNIFDESasvagGTKNSKFYLSGSYydqvgvvpet 379
Cdd:cd01347 120 -GYGSDNSGSSGGGGFDVSGALADDGAFGARLYGAYRDGDGTIDGDGQADDS-----DEERYNVAGKLDW---------- 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 380 gykkyafRFNGEQkvgifTFNASAAYSDAHTDRTltgAGLYNSSGNGALYGVYNWSPFDRMTHYQNEDGTRYRlfgdrld 459
Cdd:cd01347 184 -------RPDDDT-----RLTLDAGYQDQDADGP---GGTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKR------- 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 460 pwderdnpywivnrNHMYDDIDRFNGMLSIKADiakwwfVSYkigidRYTQTASNRLAANGVLKQVWQKGMMSDNTQQFR 539
Cdd:cd01347 242 --------------ASLGLEHDLNDTGWTLRAN------LSY-----SYTDNDGDPLILNGGNNAAGGDLGRSGYSSERD 296
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 540 YMSHDFMSNMSHKFGDF--DLNLLLGAtmdetktdrssmmawnfsvpdffSYANASKDNKQFthaatkkrlvGAFGEFRA 617
Cdd:cd01347 297 TTQLGFDAGLNAPFGTGpvAHTLTLGV-----------------------EYRREELDEKQT----------ALYAQDTI 343
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 618 SWKNMLYLTVSGRNDWTSTLPLEN----------RSYFYPSVSGSFVFTEALQrlgwlddsvlnfgkLRASWAKVgkdtg 687
Cdd:cd01347 344 ELTDDLTLTLGLRYDHYDQDSKDTiaggttakksYSHWSPSLGLVYKLTDGLS--------------LYASYSQG----- 404
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 688 vYELetalwPTGTYLDGTVGVGNTWTRGNDKLKPEMTKSTEIGVELSFFKnRLHIDYAYYTNDSYNQILAPRGPQSTGYI 767
Cdd:cd01347 405 -FRA-----PSLGELYGGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGD-GLTLSAALFRIDIKNEIVSTPTNTGLGLV 477
|
650 660 670
....*....|....*....|....*....|....
gi 492382541 768 FWSINAGNVYNKGMELSISGTPiqTKDWTWDIGL 801
Cdd:cd01347 478 TVYVNGGKARIRGVELEASYDL--TDGLGLTGSY 509
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
421-789 |
5.53e-15 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 79.04 E-value: 5.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 421 NSSGNGALYGVYNWSPFDRmthyQNEDGTRYRLFGDRLDPWDERDNPYwivNRNHMYDDIDRFNGMLSIKADIAKWWFVS 500
Cdd:pfam00593 8 LLGDDTLLTLGYDYSRYTD----GLDLGLTLDGYGNDGGYLGDRPLYY---GRDYSDTDRKRLSLGYDYDLGDGLSWLST 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 501 YKIGIDRYTQTASNRLAANGVLKQvwqkgmmSDNTQQFRYMSHDFMSNMSHKFGDFDLNLLLGATMDETKTDRSSMMAWN 580
Cdd:pfam00593 81 LRLGLRYSSLDGDYTSNSSGLSGA-------GDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 581 FSVPDFFSYANASKDNkqfthaaTKKRLVGAFGEFRASWKNMLYLTVSGRNDWTSTLP----------LENRSYFYPSVS 650
Cdd:pfam00593 154 YDPYDPANPSSSSYSD-------TTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGddgngggdnfSRSYSAFSPRLG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 651 GSFVFTEALQrlgwlddsvlnfgkLRASWAKVGKDTGVYELetalwptgtYLDGTVGVGNTWTRGNDKLKPEMTKSTEIG 730
Cdd:pfam00593 227 LVYKPTDNLS--------------LYASYSRGFRAPSLGEL---------YGSGSGGGGGAVAGGNPDLKPETSDNYELG 283
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 731 VElsFFKNRLHIDYAYYTNDSYNQILAPRGPQSTGYIFWS-INAGNVYNKGMELSISGTP 789
Cdd:pfam00593 284 LK--YDDGRLSLSLALFYIDIKNLITSDPDGPGLGGTVYTyTNVGKARIRGVELELSGRL 341
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
140-262 |
8.14e-14 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 68.45 E-value: 8.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 140 DVKSDELMKMKTANPISSLSGKVAGVNVTQSSGaaGAGAQIILRGGTSgaegkdNQPLFVVDGVifdnsssvvgnsafdg 219
Cdd:pfam07715 10 SVVTAEDIEDQGATNLADALRGVPGVSVSSGGG--GGGSSISIRGFGS------NRVLVLVDGV---------------- 65
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 492382541 220 SMRSASTTSNRLMDINPEDIESMSVLKGPaAAALYGSRAANGV 262
Cdd:pfam07715 66 PLNSGGGGSVDLNSIDPEDIERVEVLKGP-ASALYGSGAIGGV 107
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
238-268 |
4.51e-13 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 64.14 E-value: 4.51e-13
10 20 30
....*....|....*....|....*....|.
gi 492382541 238 DIESMSVLKGPAAAALYGSRAANGVILITTK 268
Cdd:TIGR04057 1 DIESISVLKDASAAAIYGSRGANGVILITTK 31
|
|
| PRK13524 |
PRK13524 |
FepA family TonB-dependent siderophore receptor; |
101-270 |
3.96e-11 |
|
FepA family TonB-dependent siderophore receptor;
Pssm-ID: 237410 [Multi-domain] Cd Length: 744 Bit Score: 67.36 E-value: 3.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 101 TNATTYTVSLQDDSQALDEVVVTAMgiKKERKALGYSMedVKSDELMKMKTANPISSLSGKVAGVNVT--QSSGAAGAGA 178
Cdd:PRK13524 22 AAEAEDAKTDDTPASHEDTIVVTAA--EQNLQAPGVST--ITAEDIRKRPPANDVSEIIRTMPGVNLTgnSTSGQRGNNR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 179 QIILRGgtsgaEGKDNQpLFVVDGvifdnsssvvgnsafdgsMRSASTTSNRLM---------DIN---PEDIESMSVLK 246
Cdd:PRK13524 98 QIDIRG-----MGPENT-LILIDG------------------KPVSSRNSVRYGwrgerdtrgDTNwvpPEMIERIEVLR 153
|
170 180
....*....|....*....|....
gi 492382541 247 GPAAAAlYGSRAANGVILITTKKG 270
Cdd:PRK13524 154 GPAAAR-YGNGAAGGVVNIITKKP 176
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
42-110 |
4.96e-11 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 59.60 E-value: 4.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 42 ITGKVLDAAGEPIIGASVLVKGSGTG----AVTDIDGNFSVEA-PVGS-TLEVSFIGYKT-----VTLKVTNATTYTVSL 110
Cdd:pfam13620 2 ISGTVTDPSGAPVPGATVTVTNTDTGtvrtTTTDADGRYRFPGlPPGTyTVTVSAPGFKTatrtgVTVTAGQTTTLDVTL 81
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
84-838 |
2.30e-10 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 64.53 E-value: 2.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 84 STLEVSFIGYKTVTLKVTNATTytvsLQDDSQALDEVVVTAMGIKKERKALGYS----------ME-----DVKSDELMK 148
Cdd:COG4773 3 ALLAGSGLAAAAAGALAQAAAA----AAAEATTLPEVTVTGTAEGTGGYTAKSSstatkldtplREtpqsvSVVTRQLIE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 149 MKTANPISSLSGKVAGVNVTQSSGaaGAGAQIILRGgtsgaegkdnqplfvvdgviFDnsssvVGNSAFDGsMRSASTTS 228
Cdd:COG4773 79 DQGATTLDDALRNVPGVTVSSYDG--GGRDSFSIRG--------------------FS-----IDNYLRDG-LPLGGFGG 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 229 nrlMDINPEDIESMSVLKGPAAAaLYGSRAANGVILITTKKgkegvvevninskftaswvkslPQTQRQyargymedqyd 308
Cdd:COG4773 131 ---GQPDTANLERVEVLKGPAGL-LYGAGSPGGLVNLVTKR----------------------PTAEPQ----------- 173
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 309 skknytGTVfnDFAYTSWgeksnaatydnigDFFQGGniFDesasvaggtknskfyLSGsyydqvgvvPETGYKKYAFRF 388
Cdd:COG4773 174 ------GEV--SLSAGSW-------------DTYRAT--AD---------------VGG---------PLNEDGTLRYRL 206
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 389 NGeqkvgiftfnasaAYSDAHTDRTltgaglYNSSGNGALYGVYNWSPFDRMT-----HYQNEDGTRYR----LFGDRLD 459
Cdd:COG4773 207 NA-------------AYEDGDSFRD------GVDNRRTLIAPSLDWDLTDDTTltlgaEYQDDDSTGDRgflpLDGTLLD 267
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 460 -PWDERDNPYWIvnrnhmYDDIDRFNGMLSIKADIAKWW-----FVSYKIGID-RYTQTASNRLAANGVLKqvwqkgmMS 532
Cdd:COG4773 268 lPRSTNLGEPWD------YYDTETTTLFAELEHRFNDDWslranARYSDSDRDgRSAYAYGAPDAATGTLT-------RY 334
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 533 DNTQQFRYMSHDFMSNMSHKF--GDFDLNLLLGATMDETKTDRSSMMAWNFSVPDFfSYANASKDNKQFTHAATKKRLVG 610
Cdd:COG4773 335 ASARDGDSRSDSLDANLNGKFetGGLEHTLLVGADYSRYDSDSDSATAGTINIYNP-VYGNLPEPDFDASDTDTTTRQTG 413
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 611 AFGEFRASWKNMLYLTVSGRNDWtstlpLENRSYFYPSVSGSFVftealqrlgwlDDSVL--NFGklrASWaKVGKDTGV 688
Cdd:COG4773 414 LYAQDQISLTDRLSLLLGGRYDW-----YETDSTNRLGGSTTSY-----------DDSAFtpRAG---LVY-DLTPGLSL 473
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 689 YeletalwptGTYLDGTVGVGNTwTRGNDKLKPEMTKSTEIGVELSFFKNRLHIDYAYYtndsynQI----LAPRGPQST 764
Cdd:COG4773 474 Y---------ASYSESFEPQSGA-DNNGNPLDPETGKQYEAGVKGELFDGRLNATLAVF------DItqknVATTDPDNP 537
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 765 GYifwSINAGNVYNKGMELSISGTPiqTKDWTWDIGL------------NMAGNRgtLDGLPEGMGVMYVT-DVQYAGMQ 831
Cdd:COG4773 538 NF---YVQVGEVRSRGVELELSGEL--TPGLNLIAGYtytdakitkdadALEGKR--LTNVPRHTASLWTTyRFPSGALK 610
|
....*..
gi 492382541 832 AASFSGG 838
Cdd:COG4773 611 GLGLGGG 617
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
103-269 |
2.43e-10 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 64.78 E-value: 2.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 103 ATTYTVSLQDDSQALDEVVVTAMGIKKERKALGYSMedVKSDELMKMKTANPISSLSGKVAGVNVT--QSSGAAGAGAQI 180
Cdd:PRK13528 20 NSPVSAAESSDDDNGETMVVEATAEQELKQQPGVSI--ITAEDIKKRPPVNDLSDIIRKMPGVNLTgnSASGTRGNNRQI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 181 ILRGgtsgaEGKDNQpLFVVDGVIFDNSSSVvgNSAFDGSmRSASTTSNRlmdINPEDIESMSVLKGPAAAAlYGSRAAN 260
Cdd:PRK13528 98 DIRG-----MGPENT-LILIDGVPVTSRNSV--RYSWRGE-RDTRGDTNW---VPPEMVERIEVIRGPAAAR-YGSGAAG 164
|
....*....
gi 492382541 261 GVILITTKK 269
Cdd:PRK13528 165 GVVNIITKR 173
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
162-796 |
4.69e-09 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 60.28 E-value: 4.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 162 VAGVnvTQSSGAAGAGAQIILRGgtsgaegkdnqplfvvdgviFDNSSSVvgnsAFDGsMRSASTTSnrlmdINPEDIES 241
Cdd:COG4774 36 VPGV--TFGAGEGGNGDSFSIRG--------------------FSASGDI----YVDG-LRDPGQYR-----RDTFNLER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 242 MSVLKGPaAAALYGSRAANGVILITTKKgkegvvevninskftaswvkslPQTQRQYargYMEDQYDSKKNYTGTVfnDF 321
Cdd:COG4774 84 VEVLKGP-ASVLYGRGSPGGVINLVTKR----------------------PTDEPFT---EVTLTYGSDGQRRATL--DV 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 322 aytswgeksNAATYDNIGdffqggnifdesASVAGGTKNSKFYLSGSYYDQVGVVPetgykkyAFRFNGeqkvgiftfna 401
Cdd:COG4774 136 ---------NGPLGDDLA------------YRLNGMYRDSDSYRDGVDNDRWGIAP-------SLTWRL----------- 176
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 402 saaysdahTDRT-LTGAGLYNSSGNGALYGVynwsPFDRMTHYQNEDGTRYrlFGdrlDPWDerdnpywivnrnhmYDDI 480
Cdd:COG4774 177 --------GDRTrLTLDYEYQDDDRTPDYGV----PAVANGRPVDVDRSTF--YG---QPDD--------------YSDS 225
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 481 DRFNGMLSIKADIAKWWFV----SYKIGIDRYTQTASNRLAANGVLKQvwqkgmmSDNTQQFRYMSHDFMSNMSHKF--G 554
Cdd:COG4774 226 ETDSATLRLEHDFNDNWTLrnalRYSDYDRDYRNTYPTGGNATGTVTR-------SAYRRDQDNDTLSNQTDLTGKFdtG 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 555 DFDLNLLLGATMDETKTDRSSM----MAWNFSVPDFFSYANASKDNKQFTHAATKKRLVGAFGEFRASWKNMLYLTVSGR 630
Cdd:COG4774 299 GVKHTLLAGVEYSREDSDNARYsgggTAPTVNLYNPVYGAPVTGPTLGGADNDSRTDTTGLYLQDTISLTDRWSLLAGLR 378
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 631 NDWTSTlplENRSYFYPSVSGSFVFTEALQRLG--WLDDSVLNfgkLRASWAkvgkdtgvyeleTALWPTGTYLDGTVgv 708
Cdd:COG4774 379 YDRFDT---DYTDRTTGATTSSYDDSAFSPRAGlvYKPTPNLS---LYASYS------------TSFNPGGGAPSLSN-- 438
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 709 gntwtrGNDKLKPEMTKSTEIGVELSFFKNRLHIDYAYYTNDSYNQILapRGPQSTGYifwSINAGNVYNKGMELSISGT 788
Cdd:COG4774 439 ------AGQALDPEKSRQYEVGVKWDLLDGRLSLTAALFRIEKTNVRT--TDPANPGV---YVQTGEQRSRGVELEATGE 507
|
....*...
gi 492382541 789 PiqTKDWT 796
Cdd:COG4774 508 L--TPGWS 513
|
|
| PRK10064 |
PRK10064 |
catecholate siderophore receptor CirA; Provisional |
103-269 |
2.73e-05 |
|
catecholate siderophore receptor CirA; Provisional
Pssm-ID: 236646 [Multi-domain] Cd Length: 663 Bit Score: 48.34 E-value: 2.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 103 ATTYTVSLQDDSQALDEVVVTAMGIKKERKALGYSMEDVKSDELMKMKTANPISSLsGKVAGVNVTqSSGAAGAGAQIil 182
Cdd:PRK10064 16 AISCAWPVLAVDDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVL-KEVPGVQLT-NEGDNRKGVSI-- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 183 RGGTSgaegkdNQPLFVVDGVIFDNSSSVVGNSAFDgsmrsasttsnrLMDINPEDIESMSVLKGPAAAaLYGSRAANGV 262
Cdd:PRK10064 92 RGLDS------SYTLILIDGKRVNSRNAVFRHNDFD------------LNWIPVDAIERIEVVRGPMSS-LYGSDALGGV 152
|
....*..
gi 492382541 263 ILITTKK 269
Cdd:PRK10064 153 VNIITKK 159
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
114-290 |
6.74e-05 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 46.94 E-value: 6.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 114 SQALDEVVVTAMGIKKERKALGYSMEDVKSDELMKMKTANPISSLSGkVAGVNVTQSSGAAGaGAQIILRGGTSgaegkd 193
Cdd:PRK13486 22 AAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRS-VEGVDVESGTGKTG-GLEISIRGMPA------ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 194 NQPLFVVDGVIFDNSSSVVGN--SAFDGSMRSASTTsnrlmdinpedIESMSVLKGPAAAaLYGSRAANGVILITTKKGK 271
Cdd:PRK13486 94 SYTLILIDGVRQGGSSDVTPNgfSAMNTGFMPPLAA-----------IERIEVIRGPMST-LYGSDAMGGVVNIITRKNA 161
|
170 180
....*....|....*....|..
gi 492382541 272 E---GVVEVNINSKFTASWVKS 290
Cdd:PRK13486 162 DkwlSSVNAGLNLQESNKWGNS 183
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
184-818 |
1.63e-04 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 45.87 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 184 GGTSGAEGKDNQPLFVVDGVifdNSSSVVGNSAFDGsmRSASTTSNRLMdINPEDIESMSVLKGPAAAaLYGSRAANGVI 263
Cdd:TIGR01783 32 VVVGGSGGTTQFGNITIRGF---GLEVDIDNVYLDG--VPLLSRGNLAI-VDPAMVERVEVLRGPASL-LYGGSAPGGVI 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 264 LITTKKGK---EGVVEVNinskftaswvkslpqtqrqyargymedqydskknytgtvfndfaytsWGEKSNAATYDNIGD 340
Cdd:TIGR01783 105 NIVTKRPQdepKGSVTFG-----------------------------------------------AGTRSGYRTAFDLGG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 341 FFQGGNIFDesasvaggtknskFYLSGSYYDqvgvvpetgyKKYAFRFNGEQKvgifTFNASAAYSDAHTDRTLT-GAGL 419
Cdd:TIGR01783 138 PLGADGTFR-------------GRLNGARQD----------GDSFYDGAGEET----RLGATATDWQLDDRTLLRlGAYY 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 420 YNSSGNGalygVYNWSPFDRMTHYQNEDGTRYRlfGDrldpwderdnpywivNRNHMYDDIDRFNGMLSIKADIAKWWFV 499
Cdd:TIGR01783 191 QKERDRG----GYGGLPASGGTSGRDLSSDRYL--GT---------------SSNRNYDDREYLSYGLSLEYQFNDVWTG 249
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 500 SYKIGIDrYTQTASNRLAANGVlkqvWQKGMMSDNTQQFRYMSHDFMS-----NMSHKFGDFDLNLLLGATMDETKTDRS 574
Cdd:TIGR01783 250 KQNLRYS-YFDTDSNQVQASGY----SSDGGLFGRSLTVVNVKQDRVQidaglDGEFETGPIEHDLLLGVSYGQRTTNRF 324
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 575 SMmaWNFSVPDFFSYANASKDNKQFTHAATKKRLVGafgefRASWKNMLYLTVSGRND-WTSTLPL---ENRSYFYPSVS 650
Cdd:TIGR01783 325 NN--TGYPSDNIYSLTATSSARTDIGDSPKDRALSS-----TTKALNGVALQRILLADkWTLTLGGrydSVDVKSNNGVA 397
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 651 GS------FVFTEALQRLGWLDDSVlnfgKLRASWAKvgkdtgvyeletALWPTGTYLDGTvgvgntwTRGNDKLKPEMT 724
Cdd:TIGR01783 398 GStgkrddSQFTPSLGVAYKPTDDW----SLYASYAE------------SFKPGGYYPKGA-------GNSGDILEPEKG 454
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 725 KSTEIGVELSFFKNRLHIdYAYYTNDSYNQILAprgpQSTGYIFwSINAGNVYNKGMELSISGTPiqTKDWTWDIGLNMA 804
Cdd:TIGR01783 455 KNYELGVRYDLGDSLLAT-AALFRITKDNQLVQ----DPVNGTF-SVNAGKTRNRGVELEARGYL--TPGLSLSAGYTYT 526
|
650
....*....|....
gi 492382541 805 GNRGTLDGLPEGMG 818
Cdd:TIGR01783 527 DAEFTEDTNGDTQG 540
|
|
| PRK13484 |
PRK13484 |
IreA family TonB-dependent siderophore receptor; |
109-268 |
1.67e-04 |
|
IreA family TonB-dependent siderophore receptor;
Pssm-ID: 139605 [Multi-domain] Cd Length: 682 Bit Score: 45.77 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 109 SLQDDSQalDEVVVTAMGIKKERKALGYSMEDVKSDELMKmktaNPISSLSGKVAGVNVTQSSGaaGAGAQIILRGGTSG 188
Cdd:PRK13484 24 ASSDKKE--DTLVVTASGFTQQLRNAPASVSVITSEQLQK----KPVSDLVDAVKDVEGISITG--GNEKPDISIRGLSG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 189 aegkdNQPLFVVDGVIFDNSSSVV-GNSAFDGSMrsasttsnrlmdINPED-IESMSVLKGPAAAaLYGSRAANGVILIT 266
Cdd:PRK13484 96 -----DYTLILVDGRRQSGRESRPnGSGGFEAGF------------IPPVEaIERIEVIRGPMSS-LYGSDAIGGVINII 157
|
..
gi 492382541 267 TK 268
Cdd:PRK13484 158 TK 159
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
103-802 |
1.89e-04 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 45.30 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 103 ATTYTVSLQDDSQALDEVVVTAMGIKKER-KALGYSMEDVKSDELMKMKTANPISSLSgKVAGVNVTQSSGAaGAGAQII 181
Cdd:COG4772 9 LLLAAAAAAEAATTLETVVVTGSRAAEARlKDVPGSVSVVDREELENQAATSLREVLR-RVPGVNVQEEDGF-GLRPNIG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 182 LRG----GTSGAegkdnqpLFVVDGVIFdnSSSVVGNSAFDgsmrsasttsnrlMDINPEDIESMSVLKGPAAAaLYGSR 257
Cdd:COG4772 87 IRGlgprRSRGI-------TLLEDGIPI--APAPYGDPAAY-------------YFPDLERMERIEVLRGAAAL-RYGPQ 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 258 AANGVILITTKKGkegvvevninskftaswvkslPQTQRQYARgymedqydskknytgtvfndFAYTSWGEksnaatydn 337
Cdd:COG4772 144 TVGGAINFVTRTI---------------------PTAFGGELR--------------------VTGGSFGY--------- 173
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 338 igdffqggniFDESASVAGGTKNSKFYLSGSYYDQVGVVPETGYKKYAFRFNGEQKVgiftfnasaaysdahTDRTLTGA 417
Cdd:COG4772 174 ----------RRTHASVGGTVGNFGYLVEYSRKRGDGFRDNSGFDINDFNAKLGYRL---------------SDRQELTL 228
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 418 GLYNSSGNGALYGvynwspfdrmthyqnedgtryrlfgdRLDPWDERDNPYW-IVNRNHMYDDIDRFNGMLSIK-ADIAK 495
Cdd:COG4772 229 KFQYYDEDANTPG--------------------------GLTDAQFDADPRQsYRPADQFDTRRTQLSLRYEHQlSDNTT 282
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 496 WWFVSYKIGIDRYTQTASNRLAANGVLKQvwqkgmMSDNTQQFRYMShdFMSNMSHKF--GDFDLNLLLGATMDETKTDR 573
Cdd:COG4772 283 LTTTAYYNDFSRNWYIRQNTADPNTPGLG------LRGNPRGYRSYG--IEPRLTHRFelGGVPHTLEVGLRYHREEEDR 354
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 574 ssmMAWNFSVPDFFSYANASKDNKQFTHAatkkrlVGAFGEFRASWKNMLYLTVSGRNDWTSTlplENRSYFYPS----V 649
Cdd:COG4772 355 ---KQYVNTYGQGRSGAGLRRDRRFSADA------LAAYAQNRFELTGRLTLTPGLRYEHIRR---DRTDRYSTRtggdD 422
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 650 SGSFVFTEALQRLGwlddsvlnfgklrASWaKVGKDTGVYeletALWPTG----TYLDGTVGVGntwtrGNDKLKPEMTK 725
Cdd:COG4772 423 SGSNSYSEFLPGLG-------------LLY-QLTDNLQLY----ANVSRGfeppTFGDLAYGNG-----GNPDLKPEKSW 479
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492382541 726 STEIGVELSFfKNRLHIDYAYYTNDSYNQILapRGPQSTGYIFWSINAGNVYNKGMELSISGTPIQTKDWTWDIGLN 802
Cdd:COG4772 480 NYELGTRGRI-GNGLSAEVALFYIDYDNELG--SCSAAGGDRSTFTNAGETRHQGLELALDYDLLKGGGLGLPLFAA 553
|
|
| OMP_b-brl_3 |
pfam14905 |
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ... |
710-812 |
2.29e-04 |
|
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.
Pssm-ID: 434300 [Multi-domain] Cd Length: 407 Bit Score: 44.96 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 710 NTWTRGNDKLKPEMTKSteigVELSF-FKNRLHID-YAYYTNDSYNQIlaPRGPQSTG-YIFWSINAGNVYNKGMELSIS 786
Cdd:pfam14905 203 YNYSQGNPNLKPEYTNS----FELGYtYKWKLSLSlSYRYTNDVIQQT--FITDDNDNvTYTTYENLGKSNSYGLELSAS 276
|
90 100
....*....|....*....|....*.
gi 492382541 787 GTPiqTKDWTWDIGLNMAGNRGTLDG 812
Cdd:pfam14905 277 FNP--TKWWSLNGNLNGYYNKYKIDG 300
|
|
| Peptidase_M14NE-CP-C_like |
cd11308 |
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ... |
42-110 |
7.78e-04 |
|
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.
Pssm-ID: 200604 [Multi-domain] Cd Length: 76 Bit Score: 39.04 E-value: 7.78e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492382541 42 ITGKVLDAAGEPIIGASVLVKGSGTGAVTDIDGNFSVEAPVGS-TLEVSFIGYKTVTLKVT-----NATTYTVSL 110
Cdd:cd11308 2 IKGFVTDATGNPIANATISVEGINHDVTTAKDGDYWRLLLPGTyNVTASAPGYQPVTKTVTvpnnfSATVVNFTL 76
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
117-798 |
5.32e-03 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 40.84 E-value: 5.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 117 LDEVVVTAMGIKKERKALGYSMEdVKSDELMKMKTANPISSLSGKVAGVNVTqsSGAAGAGAQIILRGGtsgaegKDNQP 196
Cdd:TIGR01785 1 LDTVTVTATRTRQVLSEAPASVS-VISGEQIESKQANNLADALNTVPGVDVT--GGGRPPGQSINIRGL------QDNRV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 197 LFVVDGVifdnsssvVGNSAFDGSMRSASTtsnrlmdINPEDIESMSVLKGPAAAaLYGSRAANGVILITTKKGKEgvve 276
Cdd:TIGR01785 72 LVVVDGA--------RQNYQRGGAHNGSLF-------VDPELLKRIEIVKGPSSS-LYGSGALGGVVAFRTKDAAD---- 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 277 vninskftaswvkSLPQTQRQYARGYMEdqYDSKKNYTGtvFNDFAYtswgeksnAATYDNIgDFFqggnifdesasVAG 356
Cdd:TIGR01785 132 -------------LLRPGQLFGGLAKLS--YGSNNNSFG--GSVAVA--------GRLDDNL-DAL-----------VAA 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 357 GTKNSKFYLSGSYYDqvgvVPETGYKKYAFRFNGEQKV--------GIFTFNAS--AAYSDAHTDRTLTGA--GLYNSSG 424
Cdd:TIGR01785 175 TYRDGGNYRNGNKEE----ATNSAYVQKNLLAKLGWQLddaqrlefSYFTTEGSldEAQNSGPGTEYVLGSssTLLASST 250
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 425 ---NGALygVYNWSPFDrmthyQNEDGTRYRLFGDRLDPWDERDNPYWIVNRNHMYDDIDrFNGMLSIKADIAKWWFVSY 501
Cdd:TIGR01785 251 rdrSATL--TYNWTPED-----NPWLDATASLYYNRTENDNDRSARGVGREEGYQYTTYG-ATLQNTSRFDVASWSTLTY 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 502 KIGIDRYTQTASNRlAANGVLKQVWqkgmmsdNTQQFRYMSHDFMSNMSHKFGDFDLNLLLGATMDETKTDrssmmawnf 581
Cdd:TIGR01785 323 GVDWMKDKRRTESF-DPNSVTTIVP-------NPPSAKEYFFGLFLQDNIPLLDDRLTLSAGLRYDHYKLS--------- 385
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 582 svpdffSYANASKDNKQFTHaatkkrlvgafgefraswknmlyltvsgrndwtstlplenrSYFYPSVSGSFVFTEALQr 661
Cdd:TIGR01785 386 ------PKTTADTEAVDRSY-----------------------------------------SRWSPSLGLSYKPVDWLT- 417
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492382541 662 lgwlddsvlnfgkLRASWAKVGKDTGVYELetalwpTGTYLDGTVGVGNTWtRGNDKLKPEMTKSTEIGVELSFFK---- 737
Cdd:TIGR01785 418 -------------LYASYSQGFRAPSIDEL------YGTGDHPGTPGGYTF-APNPNLKPETSKTWELGANLSFDNllld 477
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492382541 738 -NRLHIDYAYYTNDSYNQIL-----APRGPQSTGYIFWSINAGNVYNKGMELSISgtpIQTKDWTWD 798
Cdd:TIGR01785 478 nDQLQFKVAYFYNDVKDFIDltigvTDNVTAGMNNITQYVNIDGARIRGIEASAS---YDAGLWATG 541
|
|
| |
