|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
7-246 |
6.40e-93 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 274.00 E-value: 6.40e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 7 MIFGVRAVIEAIQAGKEIDKILVKKDIQSDLsKELFAVLKGTLIPVQRVPVERINRVT-RKNHQGVIAFISSVTYQKTED 85
Cdd:COG0566 28 LAEGRHAVEEALKAGREIEELLVTEGALDRL-AELLALAKAAGIPVYEVSREVLDKLSgTETHQGVLAVVRPPEYADLED 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 86 LvpfLFEQGKNPLFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREHSLKETLQF 165
Cdd:COG0566 107 L---LAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNLADALEE 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 166 LKNSGFHIVAATEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEAVKQRT 245
Cdd:COG0566 184 LKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLYEAARQRR 263
|
.
gi 492396460 246 N 246
Cdd:COG0566 264 A 264
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
98-240 |
1.06e-69 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 210.32 E-value: 1.06e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREHSLKETLQFLKNSGFHIVAAT 177
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492396460 178 EKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEA 240
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
5-244 |
3.01e-67 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 207.58 E-value: 3.01e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 5 SEMIFGVRAVIEAIQAGKEIDKILVKKDIQSdlsKELFAVLKGTLIPVQRVPVERINRVTR-KNHQGVIAFISSVTYQKT 83
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQQRVFILKGLESKRL---KKLIQLAKKQGINIQLVDRQKLDQLTKgGNHQGIAAKVKPILYKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 84 EDLVPfLFEQGKNPLFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREHSLKETL 163
Cdd:TIGR00186 78 NDLYK-TAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 164 QFLKNSGFHIVAATEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEAVKQ 243
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
.
gi 492396460 244 R 244
Cdd:TIGR00186 237 R 237
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
5-244 |
2.50e-52 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 169.76 E-value: 2.50e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 5 SEMIFGVRAVieaiqagkeidKILVKKDIQSDLskELFaVLKGT----LIPV------QRVPVERINRVTRKN------H 68
Cdd:PRK11181 2 SEIIYGIHAV-----------QALLERAPERFI--EVF-VLKGRedkrLLPLineleaQGIVIQLANRQTLDEkaegavH 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 69 QGVIAFISSVTyQKTEDLVPFLFEQGKNPLFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGAL 148
Cdd:PRK11181 68 QGIIARVKPGR-QLQENDLPDLLASLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 149 HTLPVCREHSLKETLQFLKNSGFHIVAATEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLN 228
Cdd:PRK11181 147 ETVPLIRVTNLARTMRMLQEKNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLN 226
|
250
....*....|....*.
gi 492396460 229 VSVAAGILIYEAVKQR 244
Cdd:PRK11181 227 VSVATGICLFEAVRQR 242
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
97-238 |
1.64e-50 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 161.54 E-value: 1.64e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 97 PLFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVS-VNADAMKTSAGALHTLPVCREHSLKETLQFLKNSGFHIVA 175
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADpYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492396460 176 ATEKGDyDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIY 238
Cdd:pfam00588 81 TSLGGK-SLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
8-76 |
7.50e-14 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 64.48 E-value: 7.50e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 8 IFGVRAVIEAIQAGKEIDKILVKKDIQSDLsKELFAVLKGTLIPVQRVPVERINRVT-RKNHQGVIAFIS 76
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEGRAERL-KELLKLAKERGIKVIEVSKKELDKLSgTANHQGVVAVVK 69
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
7-246 |
6.40e-93 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 274.00 E-value: 6.40e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 7 MIFGVRAVIEAIQAGKEIDKILVKKDIQSDLsKELFAVLKGTLIPVQRVPVERINRVT-RKNHQGVIAFISSVTYQKTED 85
Cdd:COG0566 28 LAEGRHAVEEALKAGREIEELLVTEGALDRL-AELLALAKAAGIPVYEVSREVLDKLSgTETHQGVLAVVRPPEYADLED 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 86 LvpfLFEQGKNPLFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREHSLKETLQF 165
Cdd:COG0566 107 L---LAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNLADALEE 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 166 LKNSGFHIVAATEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEAVKQRT 245
Cdd:COG0566 184 LKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLYEAARQRR 263
|
.
gi 492396460 246 N 246
Cdd:COG0566 264 A 264
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
98-240 |
1.06e-69 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 210.32 E-value: 1.06e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREHSLKETLQFLKNSGFHIVAAT 177
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492396460 178 EKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEA 240
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
5-244 |
3.01e-67 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 207.58 E-value: 3.01e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 5 SEMIFGVRAVIEAIQAGKEIDKILVKKDIQSdlsKELFAVLKGTLIPVQRVPVERINRVTR-KNHQGVIAFISSVTYQKT 83
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQQRVFILKGLESKRL---KKLIQLAKKQGINIQLVDRQKLDQLTKgGNHQGIAAKVKPILYKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 84 EDLVPfLFEQGKNPLFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREHSLKETL 163
Cdd:TIGR00186 78 NDLYK-TAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 164 QFLKNSGFHIVAATEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEAVKQ 243
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
.
gi 492396460 244 R 244
Cdd:TIGR00186 237 R 237
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
5-244 |
2.50e-52 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 169.76 E-value: 2.50e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 5 SEMIFGVRAVieaiqagkeidKILVKKDIQSDLskELFaVLKGT----LIPV------QRVPVERINRVTRKN------H 68
Cdd:PRK11181 2 SEIIYGIHAV-----------QALLERAPERFI--EVF-VLKGRedkrLLPLineleaQGIVIQLANRQTLDEkaegavH 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 69 QGVIAFISSVTyQKTEDLVPFLFEQGKNPLFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGAL 148
Cdd:PRK11181 68 QGIIARVKPGR-QLQENDLPDLLASLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 149 HTLPVCREHSLKETLQFLKNSGFHIVAATEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLN 228
Cdd:PRK11181 147 ETVPLIRVTNLARTMRMLQEKNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLN 226
|
250
....*....|....*.
gi 492396460 229 VSVAAGILIYEAVKQR 244
Cdd:PRK11181 227 VSVATGICLFEAVRQR 242
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
97-238 |
1.64e-50 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 161.54 E-value: 1.64e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 97 PLFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVS-VNADAMKTSAGALHTLPVCREHSLKETLQFLKNSGFHIVA 175
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADpYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492396460 176 ATEKGDyDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIY 238
Cdd:pfam00588 81 TSLGGK-SLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
98-240 |
7.39e-48 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 154.89 E-value: 7.39e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIPaRNSVSV-NADAMKTSAGALHTLPVCREHSLKETLQFLKNSGFHIVAA 176
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILS-KGTVDPyNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAA 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492396460 177 TEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEA 240
Cdd:cd18095 80 DLDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
98-244 |
3.40e-41 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 138.10 E-value: 3.40e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCrEHSLKETLQFLKNSGFHIVAAT 177
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVA-EASSEETLAWLKENKIRILATT 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492396460 178 EKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEAVKQR 244
Cdd:cd18104 80 PKAEKLYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLYEALRQR 146
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
100-244 |
3.39e-40 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 136.06 E-value: 3.39e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 100 VMLDGITDVRNFGAIARTCECAAV-DAVIIPARNSVSVNadaMKTSAGALHTLPVCREHSLKETLQFLKNSGFHIVAAT- 177
Cdd:cd18092 19 VVLENVHDPHNASAVLRTCDAFGVqDVHVIEPKNKFKKN---RGVAMGADKWLDVHRHDSTEECLAALKEQGYRIVATSl 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492396460 178 EKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEAVKQR 244
Cdd:cd18092 96 SPDAVPLDELDYTRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYELQRQR 162
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
98-239 |
9.11e-35 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 121.86 E-value: 9.11e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVcreHSLKETLQFLKNS---GFHIV 174
Cdd:cd18105 1 LWLLLDEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPI---YSVDNLASFLKSSkenGWKVV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 175 AA------TEKGDY----DYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGT-----IESLNVSVAAGILIYE 239
Cdd:cd18105 78 GTsappsaSSDKKTipanELSELLLEKPTILVLGNEGRGLRTNIKNLCDYLVSIPGGRSaenpgVDSLNVSVAAGILLHS 157
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
98-240 |
3.25e-33 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 117.28 E-value: 3.25e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREHSLKETLQFLKNSGFHIVAA- 176
Cdd:cd18097 1 LVVVLDNLRSAHNVGSIFRTADAAGVEKIYLCGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYTIIALe 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492396460 177 TEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEA 240
Cdd:cd18097 81 TTENSVPLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
100-240 |
1.20e-28 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 105.77 E-value: 1.20e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 100 VMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREHSLKETLQFLKNSGFHIVAaTEK 179
Cdd:cd18082 2 LVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIG-LEL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492396460 180 GDYD----YTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEA 240
Cdd:cd18082 81 TDGSiplsEFKFKKPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
98-246 |
6.67e-25 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 98.14 E-value: 6.67e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAA---VDAVIIPARNSVSVNadamkTSAGALHTLPVCREHSLKETLQFLKNSGFHIV 174
Cdd:PRK11081 20 LTVCMEQVHKPHNVSAIIRTADAVGvheVHAVWPGSRMRTMGS-----TAAGSNSWVQVKTHRTIGDAVAHLKGQGMQIL 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492396460 175 AATEKGD-YDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEAVKQRTN 246
Cdd:PRK11081 95 ATHLSDTaVDFREIDYTRPTCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
98-240 |
3.95e-23 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 91.30 E-value: 3.95e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREHSLKETLQFLKN-----SGFH 172
Cdd:cd18107 1 LVVLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVRVPSNRELEDWVEArkargTPLQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492396460 173 IVAATEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYEA 240
Cdd:cd18107 81 LVGTDEHGDHQIADHDFTRPTLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFLYEA 148
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
110-239 |
5.29e-23 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 91.05 E-value: 5.29e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 110 NFGAIARTCECAAVDAVIIPaRNSVSVNADAMKTSAGALHTLPV--CREHSLKETLQFLKNSGFHIVAAtEKGDYDYTKA 187
Cdd:cd18091 13 NLGGLCRTCEIFGVSKLVLP-NLAVVEDKQFKALSVSAEKWLPIeeVKPEDLLPYLKEKKQEGYTIVGL-EQTANSVSLH 90
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 492396460 188 DYTGP--MCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYE 239
Cdd:cd18091 91 DFQFPkkTVLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAIYE 144
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
98-239 |
1.68e-20 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 84.13 E-value: 1.68e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIpARNSVSV-NADAMKTSAGALHTLPVCREhSLKETLQFLKnSGFHIVAA 176
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTADWFGIRQIIC-SPDTVDPyNPKVVQASMGSIFRVQIHYT-DLPALLAELK-KAFPVYGA 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492396460 177 TEKGDyDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTI-ESLNVSVAAGILIYE 239
Cdd:cd18109 78 DLDGE-NLYEFTLPEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGKGaESLNVAVATAILLSE 140
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
110-243 |
7.29e-18 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 77.49 E-value: 7.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 110 NFGAIARTCECAAVDAVII-PArnSVSVNADAMKtSAGA--LHTLPVCREHSLKETLQFLKNSgfHIVAATEKGDYDYTK 186
Cdd:cd18094 12 NTGNIARTCAATGARLHLIePL--GFSLDDKRLK-RAGLdyWDHVDLTVHDSWEAFLEALPPG--RLFLFTTKGTKPYTD 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 492396460 187 ADYTGPMCIIMGAEDKGVSYDNLALCDEW-VKIPMLGTIESLNVSVAAGILIYEAVKQ 243
Cdd:cd18094 87 FDFKPGDYLVFGRESTGLPEEILDAFPDRrLRIPMRPKVRSLNLSNSVAIVLYEALRQ 144
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
110-243 |
1.94e-17 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 76.61 E-value: 1.94e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 110 NFGAIARTCECAAVDAVII-PARNSVSvnaDAMKTSAGA--LHTLPVCREHSLKETLQFLKNSgfHIVAATEKGDYDYTK 186
Cdd:COG0219 14 NTGNIIRLCAATGARLHLIePLGFSLD---DKKLKRAGLdyWELVDLTVHDSWEAFLEALPGG--RLFLFTTKGTKPYTD 88
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 492396460 187 ADYTGPMCIIMGAEDKGVSYDNLAL-CDEWVKIPMLGTIESLNVSVAAGILIYEAVKQ 243
Cdd:COG0219 89 VDYQPGDVLLFGRETAGLPEEVLAApADQRLRIPMRPGVRSLNLSNAVAIVLYEALRQ 146
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
100-239 |
1.75e-16 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 73.67 E-value: 1.75e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 100 VMLDGITDVRNFGAIARTCECAAVDAVIIPARNSVSVnADA--MKTSAGALHTLPVC---REhslkETLQFLKNSGFHIV 174
Cdd:cd18108 3 VVLDGVRIVGNIGAIVRTSLALGAAGIVLVDSDLATV-ADRrlLRASRGYVFSLPVVladRE----EAVAFLRDNDIPLM 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492396460 175 AATEKGDYDYTK-ADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYE 239
Cdd:cd18108 78 TLDADGDVPVKElGDRPDRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALHE 143
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
8-76 |
2.59e-16 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 71.12 E-value: 2.59e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 8 IFGVRAVIEAIQAGKEIDKILVKKDIQSDLSKELFAVLKGTLIPVQRVPVERINRVTR-KNHQGVIAFIS 76
Cdd:pfam08032 2 IYGRHAVLEALKSGPEIKKLYLTEGRRDPRLKELLKLAKERGIKVEEVDRKKLDKLSGtANHQGVVAEVK 71
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
98-239 |
1.28e-15 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 71.48 E-value: 1.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIparnsvsVNADAMKT--SAGALHTLPVCREHSLKETLQFLKNSGFHIVA 175
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEVHL-------VGRRKFNPfgAMGTDRHVKFRHFDTLAEAKEYLKERGIRLVG 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492396460 176 A-TEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTI-ESLNVSVAAGILIYE 239
Cdd:cd18096 74 VeIVPGAEPIETHPFPGDTAFVLGNEGTGLSDEQLAICDGFVYIPQYGSGtASLNVSVAASIVLHH 139
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
55-243 |
4.57e-14 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 70.58 E-value: 4.57e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 55 VPVERINRVTRKNHQGVIAFIssVTYQKTEDLVPFLFEQGKNPLFVMLDGITDVRNFGAIARTCECAAVDAVIIPARNSV 134
Cdd:PRK10864 158 VDEAELTKASGTEHHGGVCFL--IKKRNGTDVQQWLAQAGAQDCVLALEDVGNPHNLGGIMRSCAHFGVKGVVVQDAALL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 135 SVNADAMKTSAGALHTLPVcREHSLKETLQFLKNSGFHIVAATEKGDYDYTKADYTGPMCIIMGAEDKGVSYDNLALCDE 214
Cdd:PRK10864 236 ESGAAIRTAEGGAEHVQPI-TGDSFVDVLDDFRQAGYTIVTTSSHKGTPLFKASLPAKMVLVLGQEYDGLSDAARQQGDL 314
|
170 180
....*....|....*....|....*....
gi 492396460 215 WVKIPMLGTIESLNVSVAAGILIYEAVKQ 243
Cdd:PRK10864 315 SVSIDGTGNVESLNVSVATGVLLAEWWRQ 343
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
8-76 |
7.50e-14 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 64.48 E-value: 7.50e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 8 IFGVRAVIEAIQAGKEIDKILVKKDIQSDLsKELFAVLKGTLIPVQRVPVERINRVT-RKNHQGVIAFIS 76
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEGRAERL-KELLKLAKERGIKVIEVSKKELDKLSgTANHQGVVAVVK 69
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
98-240 |
4.62e-12 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 61.88 E-value: 4.62e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 98 LFVMLDGITDVRNFGAIARTCECAAVDAVIIpARNSVSV-NADAMKTSAGALHTLPV--------CREHSLKETLQFLKN 168
Cdd:cd18106 1 LTVICDNIRDPGNLGSILRSAAAAGCSKVLL-TKGCVDPwEPKVLRAGAGAHFRLPIygnlswddIPNYLPDDSKVFLAD 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492396460 169 SGFHIVaatekgdyDYTKADYT-GPMCIIMGAEDKGVSYDNLALCDEW----VKIPMLGTIESLNVSVAAGILIYEA 240
Cdd:cd18106 80 NNLPVQ--------PYDSIDYCsGPIVLVIGGETHGVSPEAYKLAHSTggsrVHIPLANGVDSLNSAVAASILLFEM 148
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
110-239 |
6.50e-11 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 58.66 E-value: 6.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 110 NFGAIARTCECAAVDAVIIPARNSVSVNADAMKTSAGALHTLPVCREH-SLKETLqflknSGFHIVAAT-----EKGDYD 183
Cdd:cd18093 13 NIGAVARAMKNFGLSDLRLVNPRCDDPEEAARALASGAEDVLENAKVYdTLEEAL-----ADCDLVVATtarprGLRRPL 87
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492396460 184 YT---------KADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYE 239
Cdd:cd18093 88 LTprelaellkEHAAGGKVALVFGREDSGLTNEELALCDLLVTIPTNPEYPSLNLAQAVAIVLYE 152
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
99-238 |
7.54e-06 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 44.18 E-value: 7.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492396460 99 FVMLDGITDVRNFGAIARTCEC--AAVDAVIIPARNSVSVNADamkTSAGALHtLPVCRehsLKETLQFLKNSGFHIV-A 175
Cdd:cd18098 2 AIGIENPKTPKNVGTLWRAAGClgASFVFTIGARYKRRKQSTD---TSKAWRH-IPLFH---YDDLEDLAEPLPFGAVlV 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492396460 176 ATEKGDYDYTKADYTGP-MCI-IMGAEDKGVSYDNLALCDEWVKIPmlgTIESLNVSVAAGILIY 238
Cdd:cd18098 75 AVELTEGATPLPDFKHPdRAVyLLGPEDGGLPQEVLARCHHVVYLP---TRGSLNVAVAGSIVLY 136
|
|
| rRNA_methyl_1 |
TIGR00050 |
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of ... |
189-239 |
1.65e-04 |
|
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of S-adenosyl-L-methionine (AdoMet)-dependent methyltransferases, and is now characterized, in E. coli, as a tRNA:Cm32/Um32 methyltransferase. It may be named TrMet(Xm32), or TrmJ, according to the nomenclature style chosen [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 272876 [Multi-domain] Cd Length: 233 Bit Score: 41.62 E-value: 1.65e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 492396460 189 YTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYE 239
Cdd:TIGR00050 102 EKGKVALVFGREDSGLTNEELQKCHVLVSIPTSEEYPSLNLSHAVAVILYE 152
|
|
| PRK10433 |
PRK10433 |
putative RNA methyltransferase; Provisional |
186-246 |
1.33e-03 |
|
putative RNA methyltransferase; Provisional
Pssm-ID: 236693 Cd Length: 228 Bit Score: 38.81 E-value: 1.33e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492396460 186 KADYTGPMCIIMGAEDKGVSYDNLALCDEWVKIPMLGTIESLNVSVAAGILIYE--AVKQRTN 246
Cdd:PRK10433 101 KSSWMSHAALVFGREDSGLTNEELALADVLTGVPMAADYPSLNLGQAVMVYCYQlaGLMQQPA 163
|
|
| |
