|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
57-621 |
2.10e-75 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 245.06 E-value: 2.10e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 57 VGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMMVTAFIGAFVSNTGTVALMLPIVVSMAASA-----NISPGR 131
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALgsekrSKFGSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 132 FLMPLAFASSMGGMATLIGTPPNLVVDEVLSNAGFTDLSFFSFTPIGVICVLIGLVVLIPLSKFFLVKKedgkdtktttg 211
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIPISFFEWMLVGLPVALVGLLLLWLVLYRLLPPE----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 212 hspkelakkyqlsdnlyriqirpgsriggkklqelnitqaynlsileirrqsssqgrflktvdqslagphtelqendily 291
Cdd:COG0471 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 292 vfgpfekvnqfakeqnleltdthVSEYVEGAEVEKLSVREIGiaevllmpdsklinkavkdsgfrdkysvnilgiqrkge 371
Cdd:COG0471 150 -----------------------IKEVPGSKEVIREELAELG-------------------------------------- 168
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 372 yilndikdikmhagdilliqgtwdsiaRMSQKqsQWVVLGqpleeaskvtldykapvaalIMVLMIAAMVFD-FIPIPPV 450
Cdd:COG0471 169 ---------------------------PLSRR--EKIALA--------------------IFALTVLLWITGsLHGIPIA 199
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 451 AAVIIAGILMVLTGCFrNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLVSGLGDYGPLVLMAGIYFTTSLL 530
Cdd:COG0471 200 VVALLGAVLLLLTGVL-TWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPLLGGLSPLLLLLLLALLTLLL 278
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 531 TMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGASMCFASPFSTPPNALVMSAGKYTFMDYVKVGLPLQIVMGIV 610
Cdd:COG0471 279 TEFASNTATAALLLPIAISLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVV 358
|
570
....*....|.
gi 492476664 611 MVFILPLLFPF 621
Cdd:COG0471 359 LLLLGPLWWPL 369
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
425-619 |
2.39e-57 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 197.81 E-value: 2.39e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 425 KAPVAALIMVLMIAAMVFDFIPIPPVAAVIIAGILMVLTGCFRNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLIS 504
Cdd:cd01115 188 IFRLAVLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALIA 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 505 EKLVSGLGDYGPLVLMAGIYFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGASMCFASPFSTPPNAL 584
Cdd:cd01115 268 EALISLLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLPVGTPPNAI 347
|
170 180 190
....*....|....*....|....*....|....*
gi 492476664 585 VMSAGKYTFMDYVKVGLPLQIVMGIVMVFILPLLF 619
Cdd:cd01115 348 VLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
5-190 |
7.18e-54 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 188.56 E-value: 7.18e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 5 LIILALSAVFFVNGKLRSDLVALCALVLLIVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAG 84
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 85 KSELKLFILIMMVTAFIGAFVSNTGTVALMLPIVVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVDEVLSNA 164
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPSRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESL 160
|
170 180
....*....|....*....|....*.
gi 492476664 165 GFTDLSFFSFTPIGVICVLIGLVVLI 190
Cdd:cd01115 161 GGQGFSFFEFTPIGLPLLIIGLLYLW 186
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
12-216 |
1.80e-43 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 159.01 E-value: 1.80e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 12 AVFFVNGKLRSDLVALCALVLLIVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLF 91
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 92 ILIMMVTAFIGAFVSNTGTVALMLPIVVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVDeVLSNAGFTDLSF 171
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIA-SALGLSFGDFGF 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 492476664 172 FSFTPIGVICVLIGLVVLIPLSKFFLVKKEDGKDTKTTTGHSPKE 216
Cdd:pfam03600 160 FMFPPVGVALLLVGLLPLLLIFRKLLPVRKEEEAELEELRKRAIK 204
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
12-205 |
6.60e-33 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 130.83 E-value: 6.60e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 12 AVFFVNGKLRSDLVALCALVLLIVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSElKLF 91
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGSR-RLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 92 ILIMMVTAFIGAFVSNTGTVALMLPIVVSMAASANISPG-RFLMPLAFASSMGGMATLIGTPPNLVVDEvLSNAGFTD-L 169
Cdd:cd00625 80 LLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPPvPLLLALAFAANIGGAATPIGNPPNLIIAS-LSGLGFLDfL 158
|
170 180 190
....*....|....*....|....*....|....*.
gi 492476664 170 SFFSFTPIGVICVLIGLVVLIPLSKFFLVKKEDGKD 205
Cdd:cd00625 159 AFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDKLTV 194
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
413-615 |
5.17e-27 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 113.50 E-value: 5.17e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 413 PLEEASKVTLDYKAPVAALIMVLMIAAMVFDFIPIPPVAAVIIAGILMVLTGcfRNVEEAYKTINWESVVLIAAMLPMSL 492
Cdd:cd00625 196 AEPLPARPLLKKFLLLALLLLLLFVLLFFFLIPLGLIALLGALLLLLLLVRG--LDPEEVLKSVDWGTLLFFAGLFVLVG 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 493 ALEKTGASNLISEKLVSGLGdYGPLVLMAGIYFTTSLLTMFISNTATAVLVAPIAL-----QSAIAINVSPYPFLLAVTV 567
Cdd:cd00625 274 ALESTGLLEWLAELLVALVG-LPPLAALLLIGLLSALLSNFISNVPTVALLLPIAAslappEPAWLALALGSTLGGNLTL 352
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 492476664 568 GASMCFASPFSTPPNALVmsagKYTFMDYVKVGLPLQIVMGIVMVFIL 615
Cdd:cd00625 353 IGSLANLIPLGAAENAGV----GISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
34-201 |
2.42e-23 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 102.90 E-value: 2.42e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMMVTAFIGAFVSNTGTVAL 113
Cdd:COG1055 37 LLLGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALL 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 114 MLPIVVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVdevlsnAGFTDLSFFSF----TPIGVICVLIGLVVL 189
Cdd:COG1055 117 LTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNPTNIMI------ASAGGLSFLDFlanlFPPSLVSLLVTLLVL 190
|
170
....*....|..
gi 492476664 190 iplskFFLVKKE 201
Cdd:COG1055 191 -----YLLFRKE 197
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
428-620 |
5.91e-23 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 101.74 E-value: 5.91e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 428 VAALIMVLMIAAMVFDFIPIPPVAAVIIAGILMVLTGcFRNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKL 507
Cdd:COG1055 4 LALAIFVLTYLLIILEPRGLNRAVAALLGAALLLLLG-VVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 508 VSgLGDYGPLVLMAGIYFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGA-SMCFASPFSTPPNALVM 586
Cdd:COG1055 83 AR-RAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAAnIGGAATPIGNPTNIMIA 161
|
170 180 190
....*....|....*....|....*....|....
gi 492476664 587 SAGKYTFMDYVKVGLPLQIVMGIVMVFILPLLFP 620
Cdd:COG1055 162 SAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFR 195
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
34-197 |
1.60e-22 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 99.46 E-value: 1.60e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILR-LAGKSELKLFILIMMVTAFIGAFVSNTGTVA 112
Cdd:COG0471 210 LLTGVLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAA 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 113 LMLPIVVSMAASANISPGRFLMPLAFASSMgGMATLIGTPPNLVVdevlsnAGFTDLSFFSFTPIGVICVLIGLVVLIPL 192
Cdd:COG0471 290 LLLPIAISLAQALGVNPLPLALAVAFAASC-AFLLPVGTPPNAIV------YGSGYYKFKDFLKVGLPLNLIGLVVLLLL 362
|
....*
gi 492476664 193 SKFFL 197
Cdd:COG0471 363 GPLWW 367
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
35-612 |
8.01e-21 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 95.49 E-value: 8.01e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 35 VFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMMV-TAFIGAFVSNT-GTVA 112
Cdd:TIGR00785 48 VLSAFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYKLVGKMGGTTLGLGYFLVFLeTLLAPMWPSNTaRAGG 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 113 LMLPIVVSMAASANISP-------GRFLM-PLAFASSMGGMATLIGTPPNLVVDEVLSNAGFTDLSFFS----FTPIGVI 180
Cdd:TIGR00785 128 ILLPIIKSLLPLLGSKPeksprkiGKYLMlGIAYSASIGSSGFLTGSAPNALAAGILSKILGIQISWGDwflaGLPLGII 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 181 CVLIGLVVLIPLSKFFLVKKEDGKdtktttghspkelakkyqlsdnlyriqirpgsRIGGKKLQELNItqaynLSILEIR 260
Cdd:TIGR00785 208 LLLLVPLLLYVLFPPELKLKDEVD--------------------------------LWAKEELEEMGP-----MSFREKA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 261 rqssSQGRFLKTVdqslagphtelqendILYVFGPFEKVNQFAkeqnleltdthvseyvegaeveklsvreigiaevllm 340
Cdd:TIGR00785 251 ----LLGIFLLAL---------------LLWIFGGSLGINASV------------------------------------- 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 341 pdsklinkavkdsgfrdkysvnilgiqrkgeyilndikdikmhagdilliqgtwdsiarmsqkqsqwvvlgqpleeaskv 420
Cdd:TIGR00785 --------------------------------------------------------------------------------
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 421 tldykapVAALIMVLMiaamvfdfipippvaavIIAGILmvltgcfrNVEEAYK-TINWESVVLIAAMLPMSLALEKTGA 499
Cdd:TIGR00785 275 -------VALLAVVLM-----------------LFLGIV--------TWKDIQKnKVAWNTLILFGGLIGLAGGLKKSGF 322
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 500 SNLISEKLVSGLGDYGPLVLMAGIYFT-TSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGAS-MCFASPF 577
Cdd:TIGR00785 323 IKWFSEKLVGILDGLSPTIAVLVLVVLfYIILYFFASNTAHTAALVPIFFSVASAQGIPLELLALALALSASlMGFLTPY 402
|
570 580 590
....*....|....*....|....*....|....*
gi 492476664 578 STPPNALVMSAGKYTFMDYVKVGLPLQIVMGIVMV 612
Cdd:TIGR00785 403 ATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLL 437
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
413-568 |
1.60e-20 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 93.15 E-value: 1.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 413 PLEEASKVTLDYKAPVAALIMVLMIAAMVFDFIPIPPVAaviIAGILMVLTGCFRNVEEAYKTINWESVVLIAAMLPMSL 492
Cdd:pfam03600 192 EAELEELRKRAIKDKLLLAISALVLALVILGFLLLSVLA---LAGALLLLLTGVLDPEEALKAVDWSTLLFFAGLFILVG 268
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492476664 493 ALEKTGASNLISEKLVsglGDYGPLVLMAGIYFTTSLLTMFISNTATAVLVAPIALQSAIAINV-SPYPFLLAVTVG 568
Cdd:pfam03600 269 ALEKTGLADALADALG---GLSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLgDPDPLAWALAVG 342
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
2-193 |
1.77e-20 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 93.80 E-value: 1.77e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 2 ITTLIILALSAVFFVNGKLRSDLVALCALVLLIVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILR 81
Cdd:cd01115 193 VLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALIAEALIS 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 82 LAGK-SELKLFILIMMVTAFIGAFVSNTGTVALMLPIVVSMAASANISPGRFLMPLAFASSMgGMATLIGTPPNLVVdev 160
Cdd:cd01115 273 LLGGlPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASC-AFMLPVGTPPNAIV--- 348
|
170 180 190
....*....|....*....|....*....|...
gi 492476664 161 lsnAGFTDLSFFSFTPIGVICVLIGLVVLIPLS 193
Cdd:cd01115 349 ---LGPGGYKFSDFAKVGLPLSILSLVVSVTMI 378
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
432-619 |
1.06e-19 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 91.49 E-value: 1.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 432 IMVLMIAAMVFDFIPIPPVAavIIAGILMVLTGCFRnVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLVSGL 511
Cdd:cd01115 3 ILVFAAVLFVTEALPLDVTA--LLVPVLLVLLGVVP-PKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 512 GDyGPLVLMAGIYFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGASM-CFASPFSTPPNALVMSA-- 588
Cdd:cd01115 80 GK-GERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPSRLLMPLAFAASIgGMLTLIGTPPNLVASGYle 158
|
170 180 190
....*....|....*....|....*....|....*
gi 492476664 589 ----GKYTFMDYVKVGLPLQIVMGIVMVFILPLLF 619
Cdd:cd01115 159 slggQGFSFFEFTPIGLPLLIIGLLYLWFIFRLAV 193
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
439-621 |
1.05e-18 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 88.46 E-value: 1.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 439 AMVFDFIPIPPVAAVIIAGILMVLTGCFRnVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLVSGLGdyGPLV 518
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVS-PKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASK--GSRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 519 LMAGIYFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPY-PFLLAVTVGASM-CFASPFSTPPNALVMSAGKYTFMDY 596
Cdd:cd00625 78 LLLLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPPvPLLLALAFAANIgGAATPIGNPPNLIIASLSGLGFLDF 157
|
170 180
....*....|....*....|....*
gi 492476664 597 VKVGLPLQIVMGIVMVFILPLLFPF 621
Cdd:cd00625 158 LAFMAPPALGLLLLLLGLLYLLFRK 182
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
444-619 |
1.08e-17 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 84.67 E-value: 1.08e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 444 FIPIPPVAAVIIAGILMVLTGcFRNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLVSgLGDYGPLVLMAGI 523
Cdd:pfam03600 6 TEKLPRDVVALLGAVLLVLLG-VLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLR-LAGGKPRRLLVAL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 524 YFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGAS-MCFASPFSTPPNALVMSAGKYTFMDYVKVGLP 602
Cdd:pfam03600 84 MLATALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANiGGTATPIGDPPNIIIASALGLSFGDFGFFMFP 163
|
170
....*....|....*..
gi 492476664 603 LQIVmGIVMVFILPLLF 619
Cdd:pfam03600 164 PVGV-ALLLVGLLPLLL 179
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
34-219 |
1.88e-17 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 84.64 E-value: 1.88e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMmVTAFIGAFVSNTGTVAL 113
Cdd:cd01117 25 LLFGVISLEDAPAAIDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGSPRRLLFLLVL-LSGILSALLTNDTACLV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 114 MLPIVVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVdevlsnAGFTDLSFFSFT----PIGVICVLIGLVVL 189
Cdd:cd01117 104 FTPIVLELARVAGLPPIPLLLALATAANIGSAATPIGNPQNLLI------ASESGISFPFFLaamaPLALLGLLLLLILL 177
|
170 180 190
....*....|....*....|....*....|
gi 492476664 190 IPLSKFFLVKKEDGKDTKTTTGHSPKELAK 219
Cdd:cd01117 178 LVLFPGELKGLPLDKATKEEGVGARKLAVK 207
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
2-192 |
2.47e-16 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 81.14 E-value: 2.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 2 ITTLIILALSAVFFVNGKLRSDLVALCALVLLIVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILR 81
Cdd:cd00625 211 LALLLLLLFVLLFFFLIPLGLIALLGALLLLLLLVRGLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVA 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 82 LAGKSELKLFILIMMVTAFIGAFVSNTGTVALMLPIVVSMAAsanisPGRFLMPLAFASSMGGMATLIGTPPNLVVDEVL 161
Cdd:cd00625 291 LVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLAP-----PEPAWLALALGSTLGGNLTLIGSLANLIPLGAA 365
|
170 180 190
....*....|....*....|....*....|.
gi 492476664 162 SNAGfTDLSFFSFTPIGVICVLIGLVVLIPL 192
Cdd:cd00625 366 ENAG-VGISFGEFLKVGLPLTLLSLVVSLLY 395
|
|
| KhtT |
COG0490 |
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) ... |
329-402 |
6.51e-16 |
|
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440256 [Multi-domain] Cd Length: 140 Bit Score: 74.96 E-value: 6.51e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492476664 329 VREIGIAEVLLMPDSKLINKAVKDSGFRDKYSVNILGIQRKGEYILNDIKDIKMHAGDILLIQGTWDSIARMSQ 402
Cdd:COG0490 65 VLLLAIEEVKVPPGSPLVGKTLGELNLRQRTGVTVVAIRRGGEVILSPGPDTVLEAGDTLVVVGTREQLERLEE 138
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
34-188 |
2.56e-15 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 78.25 E-value: 2.56e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMMVTAFIGAFVSNTGTVAL 113
Cdd:COG1055 254 LLLARVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPLVAA 333
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492476664 114 MLPIVVSMAASANISPgrFLMPLAFASSMGGMATLIGTPPNLVVDEVLSNAGFTdLSFFSFTPIGVICVLIGLVV 188
Cdd:COG1055 334 LLPLIPDLGATGNPEP--LWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIK-ISFGEFLKVGLPLTLLTLLI 405
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
34-205 |
2.83e-14 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 74.98 E-value: 2.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMMVTAFIGAFVSNTGTVAL 113
Cdd:cd01116 31 LATLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKISKGRPWRLLLLLGLLTAFLSAFLDNVTTVLL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 114 MLPIVVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVDevlSNAGftdLSFFSFTPIGVICVLIGLVVLIPLS 193
Cdd:cd01116 111 MVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIG---SAAG---LTFNDFLLHMLPSVVLALVVTFILL 184
|
170
....*....|..
gi 492476664 194 KFFLVKKEDGKD 205
Cdd:cd01116 185 YFLYRNILKARE 196
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
428-619 |
1.82e-13 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 72.47 E-value: 1.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 428 VAALIMVLMIAAMVF-DFIPIPP-VAAVIIAGILMVLTGcfRNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISE 505
Cdd:COG1055 220 ISLLVLALLLVGFVLhSFLGLPPaLIALLGAAVLLLLAR--VDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAE 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 506 KLVSGLGDyGPLVLMAGIYFTTSLLTMFISNTATAVLVAPIAlqSAIAINVSPYPFLLAVTVGAsmCFA---SPFSTPPN 582
Cdd:COG1055 298 LLASLTGG-NLLLAALLILWLSAILSAVVDNVPLVAALLPLI--PDLGATGNPEPLWLALALGA--TLGgnlTPIGSAAN 372
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 492476664 583 ALVMSA-----GKYTFMDYVKVGLPLQIV-MGIVMVFILPLLF 619
Cdd:COG1055 373 VIVLGIaekkgIKISFGEFLKVGLPLTLLtLLIALLYLLLLYF 415
|
|
| COG3273 |
COG3273 |
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only]; |
38-399 |
2.02e-12 |
|
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only];
Pssm-ID: 442504 [Multi-domain] Cd Length: 387 Bit Score: 69.31 E-value: 2.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 38 ILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMMVTAFIGAFVSNTGTVALMLPI 117
Cdd:COG3273 47 EEVLELELRMDVLQLLARMSLLLAARALEEAELLAPVLGVVAAAVAISAAAGDIAKVVLEDIGLPEAMRAALPEAVETLV 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 118 VVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVDEVLSNAGFTDLSFFSFTPIGVICVLIG-LVVLIPLSKFF 196
Cdd:COG3273 127 RATVAASSALAGRTLLLILLETETGVRVIAIRRGDDWLLNPGPTTILRADDLVLLRGPEGGILEVYLAaTGDLYERPRPP 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 197 LVKKEDGKDTKtttghspkELAKKYQLSDNLYRiqirpgsriggkklqelNITQAYNLSILEiRRQSSSQGRFLKTVDQS 276
Cdd:COG3273 207 EDSIVEMKNLS--------ELAVDLAYSSVLFD-----------------SEELAEEVRELE-EEVDALKSRLEAWVLRA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 277 LAGPHTELQENDILYVFGPFEKVNQFAKEQ-NLELTDTHVSEYVEGAEVEKlsvrEIGIAEVLLMPDSKLINKAVKDSGF 355
Cdd:COG3273 261 ARRVDDPVALRGLLHLASSTEVISDAALDIaEGVLRGLEDHPVVAEAVRES----DERIVRVTVPPGSPLVGKTLGELKL 336
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 492476664 356 RDKYSVNILGIQRKGEYILNDIKDIKMHAGDILLIQGTWDSIAR 399
Cdd:COG3273 337 ETETGVRVIAIRRGGGWIYDPDGDTRLRAGDVLIVKGTREGLER 380
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
4-143 |
2.45e-12 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 68.49 E-value: 2.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 4 TLIILALSAVFFVNGKLRSDLVALCALVLLIVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLA 83
Cdd:pfam03600 208 LLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGLS 287
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 84 GKseLKLFILIMMVTAFIGAFVSNTGTVALMLPIVVSMAASANISPgrfLMPLAFASSMG 143
Cdd:pfam03600 288 GL--LVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGD---PDPLAWALAVG 342
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
446-621 |
1.55e-11 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 66.53 E-value: 1.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 446 PIPPVAAVIIAGILMVLTGCFRnVEEAYKTINWESVVLIAAMLPMSLALEKTG----ASNLISEKLVSGLGdygplvLMA 521
Cdd:cd01117 10 RLDRWAIALLGAALMLLFGVIS-LEDAPAAIDLDTIILLFGLMVVSAALELSGffdaLGSRILVKAGSPRR------LLF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 522 GIYFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGA---SMcfASPFSTPPNALVMSAGKYTFMDYVK 598
Cdd:cd01117 83 LLVLLSGILSALLTNDTACLVFTPIVLELARVAGLPPIPLLLALATAAnigSA--ATPIGNPQNLLIASESGISFPFFLA 160
|
170 180
....*....|....*....|...
gi 492476664 599 VGLPLQIVMGIVMVFILPLLFPF 621
Cdd:cd01117 161 AMAPLALLGLLLLLILLLVLFPG 183
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
432-620 |
1.82e-11 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 66.60 E-value: 1.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 432 IMVLMIAAMVFDFIPIPPVAAVIIAgILMVLTGCF--RNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLVS 509
Cdd:TIGR00785 16 IFVAAIVGWILEPLPLPVTALLAIP-IIAVLLGVLsaFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYKLVG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 510 GLGDYGPLVLMAGIYFTTSLLTMFISNTA-TAVLVAPIALQSAIAINVSP-------YPFLL-----AVTVGASMcfaSP 576
Cdd:TIGR00785 95 KMGGTTLGLGYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLPLLGSKPeksprkiGKYLMlgiaySASIGSSG---FL 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 492476664 577 FSTPPNALVMS------AGKYTFMDYVKVGLPLQIVMGIVMVFILPLLFP 620
Cdd:TIGR00785 172 TGSAPNALAAGilskilGIQISWGDWFLAGLPLGIILLLLVPLLLYVLFP 221
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
334-400 |
7.13e-11 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 58.00 E-value: 7.13e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492476664 334 IAEVLLMPDSKLINKAVKDSGFRDKYSVNILGIQRKGEYILNDiKDIKMHAGDILLIQGTWDSIARM 400
Cdd:pfam02080 1 LVEVTVPENSPLVGKTLKELNLPERFGVRIVAIRRGGRLIIPS-GDTVLEAGDRLLVIGTPDDLAAL 66
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
432-615 |
1.44e-10 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 63.42 E-value: 1.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 432 IMVLMIAAMVF-DFIPIPPVAAVIIAGILMVLTGCFRNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLVsG 510
Cdd:cd01116 223 ILTLVIIGFVLhSPLGVSLGWIALLGALLLLLLADKLDFEDVLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLV-G 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 511 LGDYGPLVLMAGIYFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGAsmCF---ASPFSTPPNALVMS 587
Cdd:cd01116 302 VILGRIAVAVILILWISALLSAFIDNIPVTATMIPIVKDLASQLGIPLLPLWWALALGA--CLggnGTLIGASANVVAAG 379
|
170 180 190
....*....|....*....|....*....|...
gi 492476664 588 AG-----KYTFMDYVKVGLPLQIVMGIVMVFIL 615
Cdd:cd01116 380 IAeqhgyKISFWEFLKVGFPIMLVSLILATVYL 412
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
42-209 |
3.03e-10 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 62.77 E-value: 3.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 42 EEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSelKLFILIMMVTAFIGAFVSNTGTVALM----LPI 117
Cdd:pfam00939 75 SWALSGFSSTTTWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKR--TLGLGYGLVFSDLLLAPATPSNTARAggivFPI 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 118 VVSMAASANISP--------GRFLMPLAF-ASSMGGMATLIGTPPNLVVDEVLSNAGFTDLSFFS----FTPIGVICVLI 184
Cdd:pfam00939 153 IMSLPPAFGSDPekgserriGAYLMWTVYqSTSITSAMFLTAMAPNLLLLGLMNSILGVTITWASwflaAIPPGVILLLL 232
|
170 180
....*....|....*....|....*
gi 492476664 185 GLVVLIPLSKFFLVKKEDGKDTKTT 209
Cdd:pfam00939 233 APLLLYVLYPPEIKSVPDAKAIAKT 257
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
433-619 |
6.82e-10 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 61.50 E-value: 6.82e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 433 MVLMIAAMVFDFIPiPPVAAVIIAGILMV--LTGCFRNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLV-- 508
Cdd:cd01116 1 FIITYALIIFEKVH-RTVAALAGALWLVIlgLATLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVki 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 509 SGlGDYGPLVLMAGiyFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGA-SMCFASPFSTPPNALVMS 587
Cdd:cd01116 80 SK-GRPWRLLLLLG--LLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAAnIGGAATLIGDPPNIMIGS 156
|
170 180 190
....*....|....*....|....*....|..
gi 492476664 588 AGKYTFMDYVKVGLPLQIVMGIVMVFILPLLF 619
Cdd:cd01116 157 AAGLTFNDFLLHMLPSVVLALVVTFILLYFLY 188
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
34-211 |
8.23e-10 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 61.55 E-value: 8.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISsKILRLAGKSELKLFILIMMVTAFIGAFVSNTGTVAL 113
Cdd:PLN00136 47 IVFHVISPDDAYASIDLPILGLLFATMVVGSYLKNAGMFKHLG-RLLAWRSQGGRDLLCRVCVVTALASALFTNDTCCVV 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 114 MLPIVVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVvdeVLSNAGFTDLSFFsftpIGVI-CVLIGLVVLIPL 192
Cdd:PLN00136 126 LTEFVLELAAERNLPAKPFLLALASSANIGSSATPIGNPQNLV---IAFNSKITFPKFL----LGILpAMLAGMAVNMVM 198
|
170
....*....|....*....
gi 492476664 193 SKFFLVKKEDGKDTKTTTG 211
Cdd:PLN00136 199 LLCMYWKDLDGGAELSVDG 217
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
34-190 |
8.91e-10 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 61.21 E-value: 8.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSN-PIVIMMVGLFVVGGAIFKTGLAKMISSKILR-LAGKSELKLFILIMMV-TAFIGAFVSNTGT 110
Cdd:TIGR00785 284 LFLGIVTWKDIQKNKVAwNTLILFGGLIGLAGGLKKSGFIKWFSEKLVGiLDGLSPTIAVLVLVVLfYIILYFFASNTAH 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 111 VALMLPIVVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVdevlSNAGFTDLSffSFTPIGVICVLIGLVVLI 190
Cdd:TIGR00785 364 TAALVPIFFSVASAQGIPLELLALALALSASLMGFLTPYATPPNAIA----YGSGYVKIK--DMWRVGAIIGIVGLIVLL 437
|
|
| KhtT |
COG0490 |
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) ... |
226-305 |
1.76e-09 |
|
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440256 [Multi-domain] Cd Length: 140 Bit Score: 56.47 E-value: 1.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 226 NLYRIQIRPGSRIGGKKLQELNITQAYNLSILEIRRQsssqgrflktvDQSLA--GPHTELQENDILYVFGPFEKVNQFA 303
Cdd:COG0490 69 AIEEVKVPPGSPLVGKTLGELNLRQRTGVTVVAIRRG-----------GEVILspGPDTVLEAGDTLVVVGTREQLERLE 137
|
..
gi 492476664 304 KE 305
Cdd:COG0490 138 EL 139
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
430-614 |
4.31e-09 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 59.31 E-value: 4.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 430 ALIMVLMIAAMVF-DFIPIPPVAAVIIAGILMVLTGCFRNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLV 508
Cdd:pfam00939 273 LGLFVLLLLLWIFgGSLNIDATTVAIIGLALMLLLRILDWKDIVKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLS 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 509 SGLGDYGPLVLMAGIYFTTSLL-TMFISNTATAVLVAPIALQSAIAINVSPyPFLLAVTVGAS---MCFASPFSTPPNAL 584
Cdd:pfam00939 353 TSLSGFSPAMAFIIILSLFYLShYLFASATAHTAAMLPIFAAVAQAIPGAP-PLLAALLLGFAislGGFLTPYGTGPGPI 431
|
170 180 190
....*....|....*....|....*....|
gi 492476664 585 VMSAGKYTFMDYVKVGLPLQIVMGIVMVFI 614
Cdd:pfam00939 432 YFGSGYLKVKDWWRIGAILTIIGLLILLLL 461
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
34-175 |
9.72e-09 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 57.66 E-value: 9.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFS--NPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMMVTAFIGAFVSNTGTV 111
Cdd:cd01118 34 LILGLVSPHDALEVWGivWDVTLTLIGVILLSLLLDEEGFFEWVAALAARWARGSGRKLFTLIVLLGAAVTAFFANDGTA 113
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492476664 112 ALMLPIVVSMAASANISPGR---FLMPLAFASSMGGMATLIGTPPNLVVdevlsnAGFTDLSFFSFT 175
Cdd:cd01118 114 LILTPIVIALLRALGAKKNRtlpFLYACAFIADAASLPLPISNLVNIVT------AGYFGIGFTEYA 174
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
34-188 |
1.35e-08 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 57.26 E-value: 1.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMMVTAFIGAFVSNTGTVAL 113
Cdd:cd01116 254 LLADKLDFEDVLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVILILWISALLSAFIDNIPVTAT 333
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492476664 114 MLPIVVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVDEVLSNAGFTDlSFFSFTPIGVICVLIGLVV 188
Cdd:cd01116 334 MIPIVKDLASQLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKI-SFWEFLKVGFPIMLVSLIL 407
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
227-304 |
2.86e-07 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 47.99 E-value: 2.86e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492476664 227 LYRIQIRPGSRIGGKKLQELNITQAYNLSILEIRRqsssQGRFLktvdqsLAGPHTELQENDILYVFGPFEKVNQFAK 304
Cdd:pfam02080 1 LVEVTVPENSPLVGKTLKELNLPERFGVRIVAIRR----GGRLI------IPSGDTVLEAGDRLLVIGTPDDLAALRE 68
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
34-192 |
3.71e-07 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 53.07 E-value: 3.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSNPIVIMMVGLFVVGGAIFKTGLAKMI------SSKILRLAGKSELKLFILIMMVTAfigafvSN 107
Cdd:PLN00136 315 VVVDFRDAEPCLDTVSYSLLVFFSGMFITVSGFNKTGLPGAIwnfmapYSKVNSVGGISVLSVIILLLSNLA------SN 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 108 TGTVALMLPIVVsmAASANISPG---RFLMPLAFASSMGGMATLIGTPPNLVVDEVLSNA--GFTDLSFFSFTPIGVICV 182
Cdd:PLN00136 389 VPTVLLMGDEVA--AAAALISPAavtRSWLLLAWVSTVAGNLSLLGSAANLIVCEQARRAprNAYDLTFWQHIVFGVPST 466
|
170
....*....|
gi 492476664 183 LIGLVVLIPL 192
Cdd:PLN00136 467 LIVTAIGIPL 476
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
431-619 |
2.27e-06 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 50.34 E-value: 2.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 431 LIMVLMIAAMVFDFI-----PIPpVAAVIIAGILMVL-TGCFRNVEEAYKTInWESVVLIAAMLPMSLALEKTGASNLIS 504
Cdd:cd01118 1 LAIAIFVLTLVLVIWrpfglPEA-VWAVLGAVIALILgLVSPHDALEVWGIV-WDVTLTLIGVILLSLLLDEEGFFEWVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 505 EKLVSgLGDYGPLVLMAGIYFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPY---PFLLAVT-VGASMCFASPFSTP 580
Cdd:cd01118 79 ALAAR-WARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNrtlPFLYACAfIADAASLPLPISNL 157
|
170 180 190
....*....|....*....|....*....|....*....
gi 492476664 581 PNALVMSAGKYTFMDYVKVGLPLQIVMGIVMVFILPLLF 619
Cdd:cd01118 158 VNIVTAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFF 196
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
90-190 |
2.35e-06 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 50.45 E-value: 2.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 90 LFILIMMVTAFIGAFVSNTGTVALMLPIVVSMA-ASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVdevlsnAGFTD 168
Cdd:pfam00939 364 FIIILSLFYLSHYLFASATAHTAAMLPIFAAVAqAIPGAPPLLAALLLGFAISLGGFLTPYGTGPGPIY------FGSGY 437
|
90 100
....*....|....*....|..
gi 492476664 169 LSFFSFTPIGVICVLIGLVVLI 190
Cdd:pfam00939 438 LKVKDWWRIGAILTIIGLLILL 459
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
34-192 |
4.18e-06 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 49.20 E-value: 4.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 34 IVFNILTPEEALSGFSNPIVIMMVGLFVVGGAiFKTGLAKMISSKILRLAgKSELKLFIlimmVTAFIGAFVSNTGTVAL 113
Cdd:cd01117 239 LLLTRLKPRRVLKKVDWGLLLFFAGLFILVGG-FAQGLPLEGLSRLLPLL-DSVLSLFL----VSIGLSQLISNVPAVLL 312
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492476664 114 MLPIVVSmaasaniSPGRFLMPLAFASSMGGMATLIGTPPNLVVDEVLSNAGFTdLSFFSFTPIGVICVLIGLVVLIPL 192
Cdd:cd01117 313 LLPFLPS-------ADEKDWLLLAAGSTIAGNLTLLGSAANLIVAEAAERRGVR-LSFGEFLKYGVPLTLLTAAIGILW 383
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
323-389 |
4.66e-06 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 48.91 E-value: 4.66e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492476664 323 EVEKLSVREIGIAEVLLMPDSKLINKAVKDSGFRDKYSVNILGIQRKGEyILNDIKDIKMHAGDILL 389
Cdd:COG0569 231 DVLELADGDAEIVEVTVPEGSPLVGKTLKELDLRERYGVTVVAIKRGGE-VIIPSGDTVLEAGDELI 296
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
444-615 |
4.30e-05 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 46.53 E-value: 4.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 444 FIPIPPVAAVIIAGILMVLTGCFrNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLvsGLGDYGPLVLMAGI 523
Cdd:PLN00136 30 FLPIGRTAGALLSAVLMIVFHVI-SPDDAYASIDLPILGLLFATMVVGSYLKNAGMFKHLGRLL--AWRSQGGRDLLCRV 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 524 YFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVTVGASM-CFASPFSTPPNALVMSAGKYTFMDYVKVGLP 602
Cdd:PLN00136 107 CVVTALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALASSANIgSSATPIGNPQNLVIAFNSKITFPKFLLGILP 186
|
170
....*....|....
gi 492476664 603 LQIV-MGIVMVFIL 615
Cdd:PLN00136 187 AMLAgMAVNMVMLL 200
|
|
| COG3273 |
COG3273 |
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only]; |
229-305 |
1.38e-04 |
|
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only];
Pssm-ID: 442504 [Multi-domain] Cd Length: 387 Bit Score: 44.66 E-value: 1.38e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492476664 229 RIQIRPGSRIGGKKLQELNITQAYNLSILEIRRQSSSQGRflktvdqslAGPHTELQENDILYVFGPFEKVNQFAKE 305
Cdd:COG3273 317 RVTVPPGSPLVGKTLGELKLETETGVRVIAIRRGGGWIYD---------PDGDTRLRAGDVLIVKGTREGLERLEEL 384
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
176-460 |
2.17e-04 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 44.34 E-value: 2.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 176 PIGVIcVLIGLVVLIPlsKFFLVKKEdgkdtKTTTGHSPKELAKKYQLSDNLYRIQirpGSRIGGKKLQELNITQAYNLS 255
Cdd:COG2985 163 PFGVI-GIILFVALLP--KLFRIDLD-----AEAKKLEAGEGSAYPPLVTRAYRVT---NPNLVGKTVAELEALLGTRVV 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 256 ILEIRRQSssqgrflktvDQSLAGPHTELQENDILYVFGPFEKVNQFAKEQNLELTDTHVSEYVegaevekLSVREIgia 335
Cdd:COG2985 232 ISRIRRGG----------EIIVPTPDTVLQEGDIVLVVGTREALEAAEALLGEEVDDSELLDSD-------LDVRRI--- 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 336 evlLMPDSKLINKAVKDSGFRDKYSVNILGIQRKG-EYILNDikDIKMHAGDILLIQGTWDSIARMSQKqsqwvvLGQPL 414
Cdd:COG2985 292 ---VVTNKEVAGKTLGELNLRNRFGVVITRVRRGGvELPATP--DTVLQLGDRLTVVGPKEDVERVAKL------LGNSE 360
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 492476664 415 EEASKVTLdykAPVAALIMV-LMIAAMVFDFIPIPPV-----AAVIIAGILM 460
Cdd:COG2985 361 RKLSETDL---LPLGLGIVLgLLLGSIPIPLPGIPPLslglaGGPLIVGLLL 409
|
|
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
78-189 |
2.50e-04 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 44.01 E-value: 2.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 78 KILRLAGKSELKLFILIMMVTAFIGAFVSNTGTvALML-PIVVSMAASANISPGrflMPLAFASSMGGMATLIGTPpnLV 156
Cdd:PRK15445 81 HVARWAKGNGRKLFVYIVLLGAAVAALFANDGA-ALILtPIVLAMLLALGFSKK---ATLAFVMAAGFIADTASLP--LV 154
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 492476664 157 VdevlSN------AGFTDLSFFSFT----PIGVICVLIGLVVL 189
Cdd:PRK15445 155 V----SNlvnivsADYFGIGFAEYAsvmvPVNLVSLAASLLVL 193
|
|
| GntT |
COG2610 |
H+/gluconate symporter GntT or related permease, GntP/DsdX family [Carbohydrate transport and ... |
57-152 |
4.04e-03 |
|
H+/gluconate symporter GntT or related permease, GntP/DsdX family [Carbohydrate transport and metabolism];
Pssm-ID: 442022 [Multi-domain] Cd Length: 440 Bit Score: 40.10 E-value: 4.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492476664 57 VGLFVVGGAIF-----KTGLAKMISSKILRLAGKselKLFILIMMVTAF---IGAFVsNTGTVaLMLPIVVSMAASANIS 128
Cdd:COG2610 62 IGLVIGLGAMLgklleDSGAAERIADTIIKKFGE---KRAPLALVLAGFilgIPVFF-DVGFV-ILAPLAFSLARRAGIS 136
|
90 100
....*....|....*....|....
gi 492476664 129 PGRFLMPLAFASSMGGMaTLIGTP 152
Cdd:COG2610 137 KLLIGLALAAGLSTTHM-LVPPTP 159
|
|
| |
