|
Name |
Accession |
Description |
Interval |
E-value |
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
335-567 |
1.24e-74 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 238.01 E-value: 1.24e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIR 414
Cdd:COG0411 3 PLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIARLGIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RTWQTTRIAPELRVGDYIRLAA-GPIGQTELESLLGWFGCPPPE---------------------TPIASVDAGTRRLLD 472
Cdd:COG0411 83 RTFQNPRLFPELTVLENVLVAAhARLGRGLLAALLRLPRARREEreareraeellervgladradEPAGNLSYGQQRRLE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 473 VAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:COG0411 163 IARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEVRA 242
|
250
....*....|....*
gi 492864881 553 MPEVQKAYMGVDFEE 567
Cdd:COG0411 243 DPRVIEAYLGEEAAA 257
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
337-556 |
9.05e-64 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 208.83 E-value: 9.05e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRRT 416
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLGIGRT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRLAAGPIGQTEL----------------ESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVAS 479
Cdd:cd03219 81 FQIPRLFPELTVLENVMVAAQARTGSGLllararreereareraEELLERVGLADlADRPAGELSYGQQRRLEIARALAT 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 480 RAPVILLDEPAAGISYDEALKLGERIAAIPAtFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEV 556
Cdd:cd03219 161 DPKLLLLDEPAAGLNPEETEELAELIRELRE-RGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPRV 236
|
|
| LivM |
COG4177 |
ABC-type branched-chain amino acid transport system, permease component [Amino acid transport ... |
29-273 |
7.25e-52 |
|
ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 443336 [Multi-domain] Cd Length: 285 Bit Score: 179.12 E-value: 7.25e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 29 YWVFLITAVFIVGIALQSLGLVAGRTGMISLCQMSFAGVGAWVTGYLnLIEAPGGLAVWVLLGGLAAVPVGIAIGLPALR 108
Cdd:COG4177 3 YYLSLLTLILIYAILALGLNLLLGYTGLLSLGHAAFFGIGAYAAALL-TTHLGLPFWLALLLAGLVAALLGLLIGLPALR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 109 LRGINLAIVTLSFAAAFDTVLATIT--FPGQTSFTQVARPDLF----ASDRGYFLFVLLAYGIIAVVLEFISHSRLGASW 182
Cdd:COG4177 82 LRGDYLAIATLAFAEIVRLLALNLEslTGGADGLSGIPRPTLFgldlGSPLAFYYLVLALLVLVLLLLRRLVRSRFGRAL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 183 LAVRHSERAAAANGISIPRAKLSAFAISAFISGISGGLLAGYLGTLVAENFSMMQSLALFAVATMAGAHFTLGALIGGVL 262
Cdd:COG4177 162 RAIRENEIAAEALGINVTRYKLLAFVLSAALAGLAGALYAHYVGFVSPESFSFLLSIEILLMVVLGGLGSLLGPVLGAVL 241
|
250
....*....|.
gi 492864881 263 IVLFPELLRRL 273
Cdd:COG4177 242 LVLLPELLRSL 252
|
|
| TM_PBP1_LivM_like |
cd06581 |
Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two ... |
37-273 |
4.20e-50 |
|
Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.
Pssm-ID: 119323 [Multi-domain] Cd Length: 268 Bit Score: 173.78 E-value: 4.20e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 37 VFIVGIALQSLGLVAGRTGMISLCQMSFAGVGAWVTGYLnLIEAPGGLAVWVLLGGLAAVPVGIAIGLPALRLRGINLAI 116
Cdd:cd06581 1 ILIYAILALGLNLLLGYAGQLSLGHAAFFGIGAYTAALL-ATRLGLPFWLALLAAGLVAALVGLLLGLPALRLRGVYFAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 117 VTLSFAAAFDTVLATIT-FPGQTSFTQVARPDLF-----ASDRGYFLFVLLAYGIIAVVLEFISHSRLGASWLAVRHSER 190
Cdd:cd06581 80 ATLAFAEIVRLLALNWSsLTGGSNGLSGIPPPLLgglllSSPLAFYYLVLAVLLLVLLLLRRLVRSPFGRALRAIRENEV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 191 AAAANGISIPRAKLSAFAISAFISGISGGLLAGYLGTLVAENFSMMQSLALFAVATMAGAHFTLGALIGGVLIVLFPELL 270
Cdd:cd06581 160 AAEALGINVTRYKLLAFALSAALAGLAGALYAHYLGFVSPESFGFALSIELLLMVVLGGLGSLLGPVLGAALLVLLPELL 239
|
...
gi 492864881 271 RRL 273
Cdd:cd06581 240 RSL 242
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
335-562 |
1.54e-39 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 144.75 E-value: 1.54e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIR 414
Cdd:PRK11300 4 PLLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARMGVV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RTWQTTRIAPE------LRVGDYIRLAAGPIG---------QTELESL------LGWFGCpppeTPIASVDAGT-----R 468
Cdd:PRK11300 84 RTFQHVRLFREmtvienLLVAQHQQLKTGLFSgllktpafrRAESEALdraatwLERVGL----LEHANRQAGNlaygqQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 469 RLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPA 548
Cdd:PRK11300 160 RRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPE 239
|
250
....*....|....
gi 492864881 549 EVLDMPEVQKAYMG 562
Cdd:PRK11300 240 EIRNNPDVIKAYLG 253
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
335-563 |
1.83e-39 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 143.97 E-value: 1.83e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGI- 413
Cdd:COG0410 2 PMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLGIg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 -----RrtwqttRIAPE------LRVGDYIRLAAGPIGQTeLESLLGWFgcpppetPI----ASVDAGT-----RRLLDV 473
Cdd:COG0410 82 yvpegR------RIFPSltveenLLLGAYARRDRAEVRAD-LERVYELF-------PRlkerRRQRAGTlsggeQQMLAI 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 474 AGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDM 553
Cdd:COG0410 148 GRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLAD 226
|
250
....*....|
gi 492864881 554 PEVQKAYMGV 563
Cdd:COG0410 227 PEVREAYLGV 236
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
337-552 |
3.78e-39 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 143.28 E-value: 3.78e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrrT 416
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRIGY--V 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRLAAG--PIGQTEL----ESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVASRAPVILLDEP 489
Cdd:COG1131 79 PQEPALYPDLTVRENLRFFARlyGLPRKEAreriDELLELFGLTDaADRKVGTLSGGMKQRLGLALALLHDPELLILDEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 490 AAGISYDEALKLGERIAAIpATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:COG1131 159 TSGLDPEARRELWELLREL-AAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKA 220
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
334-562 |
2.53e-37 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 138.71 E-value: 2.53e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 334 GTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGI 413
Cdd:COG4674 8 GPILYVEDLTVSFDGFKALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGLDEHEIARLGI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 RRTWQTTRIAPELRVGDYIRLAAGpiGQTELESLLGWFGCPPPETPIASVdAGTRRLLDVAGAVAS-------------- 479
Cdd:COG4674 88 GRKFQKPTVFEELTVFENLELALK--GDRGVFASLFARLTAEERDRIEEV-LETIGLTDKADRLAGllshgqkqwleigm 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 480 ----RAPVILLDEPAAGISYDEALKLGERIAAIPATfgSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPE 555
Cdd:COG4674 165 llaqDPKLLLLDEPVAGMTDAETERTAELLKSLAGK--HSVVVVEHDMEFVRQIARKVTVLHQGSVLAEGSLDEVQADPR 242
|
....*..
gi 492864881 556 VQKAYMG 562
Cdd:COG4674 243 VIEVYLG 249
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
336-566 |
2.78e-37 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 138.64 E-value: 2.78e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagiRR 415
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELAR---RI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TW--QTTRIAPELRVGDYIRLAAGPigqtelesLLGWFGCPPPE-------------------TPIASVDAGTRRLLDVA 474
Cdd:COG1120 78 AYvpQEPPAPFGLTVRELVALGRYP--------HLGLFGRPSAEdreaveealertglehladRPVDELSGGERQRVLIA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 475 GAVASRAPVILLDEPAAG--ISYdeALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:COG1120 150 RALAQEPPLLLLDEPTSHldLAH--QLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLT 227
|
250
....*....|....
gi 492864881 553 MPEVQKAYmGVDFE 566
Cdd:COG1120 228 PELLEEVY-GVEAR 240
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
337-552 |
4.53e-37 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 137.18 E-value: 4.53e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRRT 416
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAGIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRLAAGPIGQTE----LESLLGWFgcpppetPI----ASVDAGT-----RRLLDVAGAVASRAPV 483
Cdd:cd03224 81 PEGRRIFPELTVEENLLLGAYARRRAKrkarLERVYELF-------PRlkerRKQLAGTlsggeQQMLAIARALMSRPKL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 484 ILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:cd03224 154 LLLDEPSEGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLA 221
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
336-550 |
1.48e-34 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 136.69 E-value: 1.48e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRR 415
Cdd:COG1129 4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDAQAAGIAI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGDYIRLA-----AGPIGQTEL----ESLLGWFGCP-PPETPIASVDAGTRRLLDVAGAVASRAPVIL 485
Cdd:COG1129 84 IHQELNLVPNLSVAENIFLGreprrGGLIDWRAMrrraRELLARLGLDiDPDTPVGDLSVAQQQLVEIARALSRDARVLI 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492864881 486 LDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVF-DfGQVIASGEPAEV 550
Cdd:COG1129 164 LDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVLrD-GRLVGTGPVAEL 227
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
336-552 |
6.95e-34 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 128.82 E-value: 6.95e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrr 415
Cdd:COG4555 1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARRQIGV-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGDYIRLAA------GPIGQTELESLLGWFGCPPP-ETPIASVDAGTRRLLDVAGAVASRAPVILLDE 488
Cdd:COG4555 79 LPDERGLYDRLTVRENIRYFAelyglfDEELKKRIEELIELLGLEEFlDRRVGELSTGMKKKVALARALVHDPKVLLLDE 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492864881 489 PAAGISYDEALKLGERIAAIpATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:COG4555 159 PTNGLDVMARRLLREILRAL-KKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELRE 221
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
338-545 |
9.42e-34 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 126.40 E-value: 9.42e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 338 EVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagirrtw 417
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELAR------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 418 qttRIApelrvgdYIRLAagpIGQTELESLLgwfgcpppETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDE 497
Cdd:cd03214 74 ---KIA-------YVPQA---LELLGLAHLA--------DRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAH 132
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 492864881 498 ALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03214 133 QIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
337-544 |
3.16e-33 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 124.46 E-value: 3.16e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRRT 416
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRDARRAGIAMV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQttriapeLRVGDyirlaagpigqtelesllgwfgcpppetpiasvdagtRRLLDVAGAVASRAPVILLDEPAAGISYD 496
Cdd:cd03216 81 YQ-------LSVGE-------------------------------------RQMVEIARALARNARLLILDEPTAALTPA 116
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 492864881 497 EALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIAS 544
Cdd:cd03216 117 EVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
335-560 |
9.81e-33 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 125.59 E-value: 9.81e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEAlsatARAKAGir 414
Cdd:COG1121 5 PAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRR----ARRRIG-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 rtW--QTTRIAPE--LRVGDYIRLAagpigqteLESLLGWFGCPPPE-------------------TPIASVDAGTR-RL 470
Cdd:COG1121 79 --YvpQRAEVDWDfpITVRDVVLMG--------RYGRRGLFRRPSRAdreavdealervgledladRPIGELSGGQQqRV 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 471 LdVAGAVASRAPVILLDEPAAGIsyDEA-----LKLGERIAAipatFGSAVLLIEHDMDLVRRACTAITVFDfGQVIASG 545
Cdd:COG1121 149 L-LARALAQDPDLLLLDEPFAGV--DAAteealYELLRELRR----EGKTILVVTHDLGAVREYFDRVLLLN-RGLVAHG 220
|
250
....*....|....*
gi 492864881 546 EPAEVLDMPEVQKAY 560
Cdd:COG1121 221 PPEEVLTPENLSRAY 235
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
337-541 |
1.13e-32 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 123.28 E-value: 1.13e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrrT 416
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRRIGY--L 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRLaagpigqteleSLlgwfgcpppetpiasvdaGTRRLLDVAGAVASRAPVILLDEPAAG---I 493
Cdd:cd03230 79 PEEPSLYENLTVRENLKL-----------SG------------------GMKQRLALAQALLHDPELLILDEPTSGldpE 129
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 492864881 494 SYDEALKLGERIAAIpatfGSAVLLIEHDMDLVRRACTAITVFDFGQV 541
Cdd:cd03230 130 SRREFWELLRELKKE----GKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
337-555 |
8.40e-32 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 122.83 E-value: 8.40e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRY-GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALS-ATARAKAGI- 413
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNlRELRRKVGLv 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 ---------------------RRTWQTTRIAPElRVGDYIRLaagpigqTELESLLgwfgcpppETPIASVDAGTRRLLD 472
Cdd:COG1122 81 fqnpddqlfaptveedvafgpENLGLPREEIRE-RVEEALEL-------VGLEHLA--------DRPPHELSGGQKQRVA 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 473 VAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:COG1122 145 IAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFS 223
|
...
gi 492864881 553 MPE 555
Cdd:COG1122 224 DYE 226
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
287-554 |
2.53e-30 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 124.63 E-value: 2.53e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 287 GAVQALSSGETIAETWTRLAEklFPRRNRQARSAAQALANSAPaigegtVLEVRDLTVRY-----GAVTALNKVNLTVPA 361
Cdd:COG1123 219 GRIVEDGPPEEILAAPQALAA--VPRLGAARGRAAPAAAAAEP------LLEVRNLSKRYpvrgkGGVRAVDDVSLTLRR 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 362 GTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagIRRTWQ------TTRIAPELRVGDYIR-- 433
Cdd:COG1123 291 GETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRE--LRRRVQmvfqdpYSSLNPRMTVGDIIAep 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 434 -LAAGPIGQTELE----SLLGWFGCPPP--ETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIA 506
Cdd:COG1123 369 lRLHGLLSRAERRervaELLERVGLPPDlaDRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLR 448
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 492864881 507 AIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:COG1123 449 DLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANP 496
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
338-540 |
1.24e-29 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 116.03 E-value: 1.24e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 338 EVRDLTVRY--GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagirr 415
Cdd:cd03225 1 ELKNLSFSYpdGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRR----- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 twqttRIA-----PE-----LRVGDYIRLAAGPIGQTE------LESLLGWFGC-PPPETPIASVDAGTRRLLDVAGAVA 478
Cdd:cd03225 76 -----KVGlvfqnPDdqffgPTVEEEVAFGLENLGLPEeeieerVEEALELVGLeGLRDRSPFTLSGGQKQRVAIAGVLA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 479 SRAPVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQ 540
Cdd:cd03225 151 MDPDILLLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
334-560 |
1.82e-28 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 117.64 E-value: 1.82e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 334 GTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAgI 413
Cdd:PRK09536 1 MPMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRR-V 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 RRTWQTTRIAPELRVGDYIRLA----------AGPIGQTELESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVASRAP 482
Cdd:PRK09536 80 ASVPQDTSLSFEFDVRQVVEMGrtphrsrfdtWTETDRAAVERAMERTGVAQfADRPVTSLSGGERQRVLLARALAQATP 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 483 VILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEVQKAY 560
Cdd:PRK09536 160 VLLLDEPTASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADTLRAAF 236
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
338-540 |
2.68e-28 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 110.41 E-value: 2.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 338 EVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEAL-SATARAKAGIRrt 416
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLpLEELRRRIGYV-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 wqttriaPELrvgdyirlaagpigqteleSllgwfgcpppetpiasvdAGTRRLLDVAGAVASRAPVILLDEPAAGISYD 496
Cdd:cd00267 79 -------PQL-------------------S------------------GGQRQRVALARALLLNPDLLLLDEPTSGLDPA 114
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 492864881 497 EALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQ 540
Cdd:cd00267 115 SRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
336-566 |
5.25e-28 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 112.43 E-value: 5.25e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRR 415
Cdd:COG1137 3 TLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRARLGIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGDYIRLAAGPIG------QTELESLLGWFGCpppeTPIASVDA-----GTRRLLDVAGAVASRAPVI 484
Cdd:COG1137 83 LPQEASIFRKLTVEDNILAVLELRKlskkerEERLEELLEEFGI----THLRKSKAyslsgGERRRVEIARALATNPKFI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 485 LLDEPAAG---ISYDEA----LKLGERiaaipatfGSAVLLIEHD----MDLVRRACtaItVFDfGQVIASGEPAEVLDM 553
Cdd:COG1137 159 LLDEPFAGvdpIAVADIqkiiRHLKER--------GIGVLITDHNvretLGICDRAY--I-ISE-GKVLAEGTPEEILNN 226
|
250
....*....|...
gi 492864881 554 PEVQKAYMGVDFE 566
Cdd:COG1137 227 PLVRKVYLGEDFR 239
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
335-555 |
3.74e-27 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 115.00 E-value: 3.74e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRY--GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP---RYDGTVLLHGKPLEALSATARA 409
Cdd:COG1123 3 PLLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPhggRISGEVLLDGRDLLELSEALRG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 410 K-AGIRRTWQTTRIAPeLRVGDYIR--LAAGPIGQTEL----ESLLGWFGCPPP-ETPIASVDAGTRRLLDVAGAVASRA 481
Cdd:COG1123 83 RrIGMVFQDPMTQLNP-VTVGDQIAeaLENLGLSRAEArarvLELLEAVGLERRlDRYPHQLSGGQRQRVAIAMALALDP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492864881 482 PVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPE 555
Cdd:COG1123 162 DLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQ 235
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
337-562 |
2.58e-26 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 107.24 E-value: 2.58e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRRT 416
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLGIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRLAAGPIG------QTELESLLGWFGCPPPE-TPIASVDAGTRRLLDVAGAVASRAPVILLDEP 489
Cdd:cd03218 81 PQEASIFRKLTVEENILAVLEIRGlskkerEEKLEELLEEFHITHLRkSKASSLSGGERRRVEIARALATNPKFLLLDEP 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 490 AAGIsyDE-ALKLGERIAAIPATFGSAVLLIEHD----MDLVRRactAITVFDfGQVIASGEPAEVLDMPEVQKAYMG 562
Cdd:cd03218 161 FAGV--DPiAVQDIQKIIKILKDRGIGVLITDHNvretLSITDR---AYIIYE-GKVLAEGTPEEIAANELVRKVYLG 232
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
336-538 |
3.62e-26 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 106.02 E-value: 3.62e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrr 415
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRRRLAY-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGDYIRLAAG----PIGQTELESLLGWFGCPPPE-TPIASVDAGTRRLLDVAGAVASRAPVILLDEPA 490
Cdd:COG4133 80 LGHADGLKPELTVRENLRFWAAlyglRADREAIDEALEAVGLAGLAdLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPF 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 492864881 491 AGISYDEALKLGERIAAIPATfGSAVLLIEHDmDLVRRACTAITVFDF 538
Cdd:COG4133 160 TALDAAGVALLAELIAAHLAR-GGAVLLTTHQ-PLELAAARVLDLGDF 205
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
337-560 |
7.16e-26 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 106.74 E-value: 7.16e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagiRRT 416
Cdd:COG4559 2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELAR---RRA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 W--QTTRIAPELRVGDYIRLAagpigqtelesLLGWFGCPPPETPIAS-----VDAGT--------------------RR 469
Cdd:COG4559 79 VlpQHSSLAFPFTVEEVVALG-----------RAPHGSSAAQDRQIVRealalVGLAHlagrsyqtlsggeqqrvqlaRV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 470 LLDVAGAVASRAPVILLDEPAAgisydeALKLGE-----RIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIAS 544
Cdd:COG4559 148 LAQLWEPVDGGPRWLFLDEPTS------ALDLAHqhavlRLARQLARRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQ 221
|
250
....*....|....*.
gi 492864881 545 GEPAEVLDMPEVQKAY 560
Cdd:COG4559 222 GTPEEVLTDELLERVY 237
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
335-551 |
3.60e-25 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 104.85 E-value: 3.60e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagiR 414
Cdd:PRK13548 1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELAR---R 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RTW--QTTRIAPELRVGDYIRLAAGP--IGQTELESLlgwfgcppPETPIASVDA---GTRRLLDVAG------------ 475
Cdd:PRK13548 78 RAVlpQHSSLSFPFTVEEVVAMGRAPhgLSRAEDDAL--------VAAALAQVDLahlAGRDYPQLSGgeqqrvqlarvl 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 476 ----AVASRAPVILLDEPAAgisydeALKLG--ERIAAIPATF----GSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:PRK13548 150 aqlwEPDGPPRWLLLDEPTS------ALDLAhqHHVLRLARQLaherGLAVIVVLHDLNLAARYADRIVLLHQGRLVADG 223
|
....*.
gi 492864881 546 EPAEVL 551
Cdd:PRK13548 224 TPAEVL 229
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
338-545 |
3.86e-25 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 103.38 E-value: 3.86e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 338 EVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEAlsatARAKAGirrtW 417
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEK----ERKRIG----Y 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 418 --QTTRIAPE--LRVGDYIRLAagpigqteLESLLGWFGCPPPET-------------------PIASVDAGTR-RLLdV 473
Cdd:cd03235 73 vpQRRSIDRDfpISVRDVVLMG--------LYGHKGLFRRLSKADkakvdealervglseladrQIGELSGGQQqRVL-L 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 474 AGAVASRAPVILLDEPAAGI---SYDEALKLGERIAAIpatfGSAVLLIEHDMDLVRRACTAITVFDfGQVIASG 545
Cdd:cd03235 144 ARALVQDPDLLLLDEPFAGVdpkTQEDIYELLRELRRE----GMTILVVTHDLGLVLEYFDRVLLLN-RTVVASG 213
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
337-540 |
2.78e-24 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 99.95 E-value: 2.78e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagiRRT 416
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPL---RRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 W----QTTRIAPELRVGDYIRLAagpigqtelesLLGwfgcpppetpiasvdaGTRRLLDVAGAVASRAPVILLDEPAAG 492
Cdd:cd03229 78 IgmvfQDFALFPHLTVLENIALG-----------LSG----------------GQQQRVALARALAMDPDVLLLDEPTSA 130
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 492864881 493 ---ISYDEALKLgerIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQ 540
Cdd:cd03229 131 ldpITRREVRAL---LKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
337-549 |
5.47e-24 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 100.14 E-value: 5.47e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrrT 416
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREVRRRIGI--V 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRLAA------GPIGQTELESLLGWFGC-PPPETPIASVDAGTRRLLDVAGAVASRAPVILLDEP 489
Cdd:cd03265 79 FQDLSVDDELTGWENLYIHArlygvpGAERRERIDELLDFVGLlEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 490 AAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAE 549
Cdd:cd03265 159 TIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEE 218
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
335-566 |
7.08e-24 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 100.86 E-value: 7.08e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKA--- 411
Cdd:PRK11231 1 MTLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRlal 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 ---------GI---------RRTWQTT--RIAPELRvgdyiRLAAGPIGQTELESLlgwfgcppPETPIASVDAGTRRLL 471
Cdd:PRK11231 81 lpqhhltpeGItvrelvaygRSPWLSLwgRLSAEDN-----ARVNQAMEQTRINHL--------ADRRLTDLSGGQRQRA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 472 DVAGAVASRAPVILLDEPAA--GISYD-EALKL-GERIAAipatfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEP 547
Cdd:PRK11231 148 FLAMVLAQDTPVVLLDEPTTylDINHQvELMRLmRELNTQ-----GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTP 222
|
250
....*....|....*....
gi 492864881 548 AEVLdMPEVQKAYMGVDFE 566
Cdd:PRK11231 223 EEVM-TPGLLRTVFDVEAE 240
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
306-551 |
7.20e-24 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 105.61 E-value: 7.20e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 306 AEKLFPRRNRQARSAAQAlaNSAPAIGEGTVLEVRDLTVRY-GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAG 384
Cdd:COG4988 308 AEKIFALLDAPEPAAPAG--TAPLPAAGPPSIELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLG 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 385 FLPRYDGTVLLHGKPLEALSATARAKagiRRTW--QTTRIaPELRVGDYIRLAAGPIGQTELESLL-------------- 448
Cdd:COG4988 386 FLPPYSGSILINGVDLSDLDPASWRR---QIAWvpQNPYL-FAGTIRENLRLGRPDASDEELEAALeaagldefvaalpd 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 449 GWfgcpppETPI----ASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPAtfGSAVLLIEHDMD 524
Cdd:COG4988 462 GL------DTPLgeggRGLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRLA 533
|
250 260
....*....|....*....|....*..
gi 492864881 525 LVRRAcTAITVFDFGQVIASGEPAEVL 551
Cdd:COG4988 534 LLAQA-DRILVLDDGRIVEQGTHEELL 559
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
336-556 |
4.44e-23 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 102.60 E-value: 4.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPR--YDGTVLLHGKPLEALSATARAKAGI 413
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHgtWDGEIYWSGSPLKASNIRDTERAGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 RRTWQTTRIAPELRV------GDYIRLAAGPIGQTEL----ESLLGWFGCP--PPETPIASVDAGTRRLLDVAGAVASRA 481
Cdd:TIGR02633 81 VIIHQELTLVPELSVaeniflGNEITLPGGRMAYNAMylraKNLLRELQLDadNVTRPVGDYGGGQQQLVEIAKALNKQA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 482 PVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASgEPAEVLDMPEV 556
Cdd:TIGR02633 161 RLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHVAT-KDMSTMSEDDI 233
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
336-545 |
4.70e-23 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 97.96 E-value: 4.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRY----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAka 411
Cdd:cd03257 1 LLEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRK-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 gIRRtwqtTRIA-----------PELRVGDYI----RLAAGPIGQTELE--SLLGWFGCPPPET-----PiASVDAGTRR 469
Cdd:cd03257 79 -IRR----KEIQmvfqdpmsslnPRMTIGEQIaeplRIHGKLSKKEARKeaVLLLLVGVGLPEEvlnryP-HELSGGQRQ 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 470 LLDVAGAVASRAPVILLDEPAAGI---SYDEALKLgerIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03257 153 RVAIARALALNPKLLIADEPTSALdvsVQAQILDL---LKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
337-556 |
6.89e-23 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 102.30 E-value: 6.89e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRRT 416
Cdd:PRK11288 5 LSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAALAAGVAII 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRL-----AAGPIGQTELES----LLGWFGCP-PPETPIASVDAGTRRLLDVAGAVASRAPVILL 486
Cdd:PRK11288 85 YQELHLVPEMTVAENLYLgqlphKGGIVNRRLLNYeareQLEHLGVDiDPDTPLKYLSIGQRQMVEIAKALARNARVIAF 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 487 DEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEpaevlDMPEV 556
Cdd:PRK11288 165 DEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVATFD-----DMAQV 228
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
337-552 |
7.71e-23 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 97.57 E-value: 7.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagIRRT 416
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYR--LRRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 W----QTTRIAPELRVGDYI--------RLAAGPIGQTELESlLGWFGCPPPET--PiASVDAGTRRLLDVAGAVASRAP 482
Cdd:cd03261 79 MgmlfQSGALFDSLTVFENVafplrehtRLSEEEIREIVLEK-LEAVGLRGAEDlyP-AELSGGMKKRVALARALALDPE 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 483 VILLDEPAAG---ISydeALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:cd03261 157 LLLYDEPTAGldpIA---SGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
337-549 |
9.09e-23 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 96.81 E-value: 9.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYG--AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGI- 413
Cdd:cd03263 1 LQIRNLTKTYKkgTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSLGYc 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 ---RRTWqttriaPELRVGDYIRLAAG----PIGQTELES--LLGWFGCPPPE-TPIASVDAGTRRLLDVAGAVASRAPV 483
Cdd:cd03263 81 pqfDALF------DELTVREHLRFYARlkglPKSEIKEEVelLLRVLGLTDKAnKRARTLSGGMKRKLSLAIALIGGPSV 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 484 ILLDEPAAGIsyDEALK--LGERIAAIPAtfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAE 549
Cdd:cd03263 155 LLLDEPTSGL--DPASRraIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQE 218
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
336-556 |
1.22e-22 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 101.54 E-value: 1.22e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPR--YDGTVLLHGKPLEALSATARAKAGI 413
Cdd:PRK13549 5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHgtYEGEIIFEGEELQASNIRDTERAGI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 RRTWQTTRIAPELRVGDYIRLAA--GPIGQT-------ELESLLGWFGCP-PPETPIASVDAGTRRLLDVAGAVASRAPV 483
Cdd:PRK13549 85 AIIHQELALVKELSVLENIFLGNeiTPGGIMdydamylRAQKLLAQLKLDiNPATPVGNLGLGQQQLVEIAKALNKQARL 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 484 ILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASgEPAEVLDMPEV 556
Cdd:PRK13549 165 LILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGRHIGT-RPAAGMTEDDI 235
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
337-521 |
1.74e-22 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 95.29 E-value: 1.74e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFlPRY---DGTVLLHGKPLEALSATARAKAGI 413
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGH-PKYevtEGEILFKGEDITDLPPEERARLGI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 RRTWQTTRIAPELRVGDYIRlaagpigqtelesllgwfgcpppetpiaSVDA----GTRRLLDVAGAVASRAPVILLDEP 489
Cdd:cd03217 80 FLAFQYPPEIPGVKNADFLR----------------------------YVNEgfsgGEKKRNEILQLLLLEPDLAILDEP 131
|
170 180 190
....*....|....*....|....*....|..
gi 492864881 490 AAGISYDeALKLGERIAAIPATFGSAVLLIEH 521
Cdd:cd03217 132 DSGLDID-ALRLVAEVINKLREEGKSVLIITH 162
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
352-491 |
2.91e-22 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 93.10 E-value: 2.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 352 LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARaKAGIRRTWQTTRIAPELRVGDY 431
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSL-RKEIGYVFQDPQLFPRLTVREN 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492864881 432 IRLAAGPIGQT------ELESLLGWFGCPP-PETPIASVDA----GTRRLLDVAGAVASRAPVILLDEPAA 491
Cdd:pfam00005 80 LRLGLLLKGLSkrekdaRAEEALEKLGLGDlADRPVGERPGtlsgGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| BPD_transp_2 |
pfam02653 |
Branched-chain amino acid transport system / permease component; This is a large family mainly ... |
31-271 |
3.03e-22 |
|
Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.
Pssm-ID: 396977 [Multi-domain] Cd Length: 269 Bit Score: 96.56 E-value: 3.03e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 31 VFLITAVFIVGIALQSLGLVAGRTGMISLCQMSFAGVGAWVTGYLNLiEAPGGLAVWVLLGGLAAVPVGIAIGLPALRLR 110
Cdd:pfam02653 3 LNILTLASIYAIAALGLTLIYGIAGVINLGHGGFMMLGAYVAAMLLN-LLGPGLWLALPVGILVGAAVGLLIGILTLRLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 111 GINLAIVTLSFAAAF---DTVLATITFPGQTSFTQVARPDLFASDRGYFLFVLLAYGIIAVVL--EFISHSRLGASWLAV 185
Cdd:pfam02653 82 INEVIITLLLNLAALglaLFLVTGILGGEGGTSGITGPSGFPGAFLSFAFAFIFLLALLLVLAlwLLLYRTKFGRALRAV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 186 RHSERAAAANGISIPRAKLSAFAISAFISGISGGLLAGYLGTLVAENFSMMQSLALFAVATMAGAHFTLGALIGGVLIVL 265
Cdd:pfam02653 162 GENEEAARAAGINVKKLKLLTFVISGALAGLAGALLALYTGVVPPSNFGVGLGLDAIAAVVLGGAGSPIGVVIGSLIIGL 241
|
....*.
gi 492864881 266 FPELLR 271
Cdd:pfam02653 242 VQSLGL 247
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
336-550 |
3.29e-22 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 100.10 E-value: 3.29e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRR 415
Cdd:COG3845 5 ALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRDAIALGIGM 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGDYIRLAAGPIGQ---------TELESLLGWFGCP-PPETPIASVDAGTRRLLDVAGAVASRAPVIL 485
Cdd:COG3845 85 VHQHFMLVPNLTVAENIVLGLEPTKGgrldrkaarARIRELSERYGLDvDPDAKVEDLSVGEQQRVEILKALYRGARILI 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 486 LDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEV 550
Cdd:COG3845 165 LDEPTAVLTPQEADELFEILRRLAAE-GKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAET 228
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
338-531 |
4.83e-22 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 94.25 E-value: 4.83e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 338 EVRDLTVRYGAVT-ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPlealsatARAKAGIRRT 416
Cdd:cd03226 1 RIENISFSYKKGTeILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKP-------IKAKERRKSI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 W---QTTR-------IAPELRVGDyiRLAAGPIGQTE-LESLLGWFGcpPPETPIASVDAGTRRLLDVAGAVASRAPVIL 485
Cdd:cd03226 74 GyvmQDVDyqlftdsVREELLLGL--KELDAGNEQAEtVLKDLDLYA--LKERHPLSLSGGQKQRLAIAAALLSGKDLLI 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 492864881 486 LDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACT 531
Cdd:cd03226 150 FDEPTSGLDYKNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCD 194
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
336-552 |
8.12e-22 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 95.95 E-value: 8.12e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLealsataraKAGIRR 415
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPL---------DPEDRR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 twqttRIA--PE-------LRVGDYIR-LAA-----GPIGQTELESLLGWFGCPppetpiasvDAGTRRL---------- 470
Cdd:COG4152 72 -----RIGylPEerglypkMKVGEQLVyLARlkglsKAEAKRRADEWLERLGLG---------DRANKKVeelskgnqqk 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 471 LDVAGAVASRAPVILLDEPAAGIsyD----EALK--LGERIAAipatfGSAVLLIEHDMDLVRRACTAITVFDFGQVIAS 544
Cdd:COG4152 138 VQLIAALLHDPELLILDEPFSGL--DpvnvELLKdvIRELAAK-----GTTVIFSSHQMELVEELCDRIVIINKGRKVLS 210
|
....*...
gi 492864881 545 GEPAEVLD 552
Cdd:COG4152 211 GSVDEIRR 218
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
312-542 |
1.34e-21 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 98.21 E-value: 1.34e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 312 RRNRQARS---AAQALANSAPAIGEGT--------------VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAG 374
Cdd:COG0488 274 RKAKQAQSrikALEKLEREEPPRRDKTveirfppperlgkkVLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAG 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 375 KSTLVDAIAGFLPRYDGTVllhgkplealsataraKAGirrtwQTTRIA----------PELRVGDYIRLAAGPIGQTEL 444
Cdd:COG0488 354 KSTLLKLLAGELEPDSGTV----------------KLG-----ETVKIGyfdqhqeeldPDKTVLDELRDGAPGGTEQEV 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 445 ESLLGWFGCPPPE--TPIASVDAGTRRLLDVAGAVASRAPVILLDEP-----AAGIsydEALklgerIAAIpATFGSAVL 517
Cdd:COG0488 413 RGYLGRFLFSGDDafKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPtnhldIETL---EAL-----EEAL-DDFPGTVL 483
|
250 260
....*....|....*....|....*
gi 492864881 518 LIEHDMDLVRRACTAITVFDFGQVI 542
Cdd:COG0488 484 LVSHDRYFLDRVATRILEFEDGGVR 508
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
337-545 |
1.48e-21 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 93.11 E-value: 1.48e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPleaLSATARAKAGI--- 413
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKP---LDIAARNRIGYlpe 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 -RRTWQTTRIAPELRvgdYI-RLAAGPI--GQTELESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVASRAPVILLDE 488
Cdd:cd03269 78 eRGLYPKMKVIDQLV---YLaQLKGLKKeeARRRIDEWLERLELSEyANKRVEELSKGNQQKVQFIAAVIHDPELLILDE 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 489 PAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03269 155 PFSGLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
336-565 |
2.10e-21 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 93.42 E-value: 2.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRR 415
Cdd:PRK10895 3 TLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGDYIrLAAGPI--------GQTELESLLGWFGCPPPETPIA-SVDAGTRRLLDVAGAVASRAPVILL 486
Cdd:PRK10895 83 LPQEASIFRRLSVYDNL-MAVLQIrddlsaeqREDRANELMEEFHIEHLRDSMGqSLSGGERRRVEIARALAANPKFILL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 487 DEPAAGISYDEALKLgERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEVQKAYMGVDF 565
Cdd:PRK10895 162 DEPFAGVDPISVIDI-KRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLGEDF 239
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
336-549 |
3.08e-21 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 97.04 E-value: 3.08e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRR 415
Cdd:PRK15439 11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAHQLGIYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGDYI--RLAAGPIGQTELESLLGWFGCP-PPETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAG 492
Cdd:PRK15439 91 VPQEPLLFPNLSVKENIlfGLPKRQASMQKMKQLLAALGCQlDLDSSAGSLEVADRQIVEILRGLMRDSRILILDEPTAS 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 493 ISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAE 549
Cdd:PRK15439 171 LTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTAD 226
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
337-529 |
8.86e-21 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 89.75 E-value: 8.86e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYG--AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagir 414
Cdd:cd03228 1 IEFKNVSFSYPgrPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRK---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 rtwqttRIApelrvgdYIR----LAAGPIgqteLESLLgwfgcpppetpiaSvdAGTRRLLDVAGAVASRAPVILLDEPA 490
Cdd:cd03228 77 ------NIA-------YVPqdpfLFSGTI----RENIL-------------S--GGQRQRIAIARALLRDPPILILDEAT 124
|
170 180 190
....*....|....*....|....*....|....*....
gi 492864881 491 AGISYDEALKLGERIAAIPAtfGSAVLLIEHDMDLVRRA 529
Cdd:cd03228 125 SALDPETEALILEALRALAK--GKTVIVIAHRLSTIRDA 161
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
298-552 |
1.03e-20 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 93.74 E-value: 1.03e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 298 IAETWTRLAEKLFPRRNRQARSAAQalaNSAPAIGEGTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKST 377
Cdd:PRK13536 6 VAEEAPRRLELSPIERKHQGISEAK---ASIPGSMSTVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKST 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 378 LVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrrTWQTTRIAPELRV-------GDYIRLAAGPIgQTELESLLGW 450
Cdd:PRK13536 83 IARMILGMTSPDAGKITVLGVPVPARARLARARIGV--VPQFDNLDLEFTVrenllvfGRYFGMSTREI-EAVIPSLLEF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 451 FGCP-PPETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRA 529
Cdd:PRK13536 160 ARLEsKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERL 238
|
250 260
....*....|....*....|...
gi 492864881 530 CTAITVFDFGQVIASGEPAEVLD 552
Cdd:PRK13536 239 CDRLCVLEAGRKIAEGRPHALID 261
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
337-444 |
1.05e-20 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 91.67 E-value: 1.05e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFlPRY---DGTVLLHGKPLEALSATARAKAGI 413
Cdd:COG0396 1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGH-PKYevtSGSILLDGEDILELSPDERARAGI 79
|
90 100 110
....*....|....*....|....*....|..
gi 492864881 414 RRTWQT-TRIaPELRVGDYIRLAAGPIGQTEL 444
Cdd:COG0396 80 FLAFQYpVEI-PGVSVSNFLRTALNARRGEEL 110
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
337-552 |
2.25e-20 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 90.32 E-value: 2.25e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGA-VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSA----TARAKA 411
Cdd:cd03256 1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGkalrQLRRQI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 GIrrTWQTTRIAPELRVGDYI---RLAAGPIGQteleSLLGWFgcPPPETPIAS---------------VDA---GTRRL 470
Cdd:cd03256 81 GM--IFQQFNLIERLSVLENVlsgRLGRRSTWR----SLFGLF--PKEEKQRALaalervglldkayqrADQlsgGQQQR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 471 LDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEV 550
Cdd:cd03256 153 VAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
|
..
gi 492864881 551 LD 552
Cdd:cd03256 233 TD 234
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
336-556 |
3.43e-20 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 90.84 E-value: 3.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEAlsaTARAKAGIRR 415
Cdd:PRK13638 1 MLATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDY---SKRGLLALRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRvgdyirlaagpIGQTELESLLGW----FGCPPPE-------------------TPIASVDAGTRRLLD 472
Cdd:PRK13638 78 QVATVFQDPEQQ-----------IFYTDIDSDIAFslrnLGVPEAEitrrvdealtlvdaqhfrhQPIQCLSHGQKKRVA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 473 VAGAVASRAPVILLDEPAAGIS---YDEALKLGERIAAIpatfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAE 549
Cdd:PRK13638 147 IAGALVLQARYLLLDEPTAGLDpagRTQMIAIIRRIVAQ----GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGE 222
|
....*..
gi 492864881 550 VLDMPEV 556
Cdd:PRK13638 223 VFACTEA 229
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
337-545 |
5.70e-20 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 88.35 E-value: 5.70e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARakaGIRRT 416
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERR---NIGMV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYI-------RLAAGPIGQTELESLLGwFGCPPPET-PIASVDAGTRRLLDVAGAVASRAPVILLDE 488
Cdd:cd03259 78 FQDYALFPHLTVAENIafglklrGVPKAEIRARVRELLEL-VGLEGLLNrYPHELSGGQQQRVALARALAREPSLLLLDE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 489 PAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03259 157 PLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
337-566 |
3.93e-19 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 86.82 E-value: 3.93e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTV--RYGAVTAlnkvnlTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPrYDGTVLLHGKPLEALSATARAKagiR 414
Cdd:COG4138 1 LQLNDVAVagRLGPISA------QVNAGELIHLIGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDWSAAELAR---H 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RTW--QTTRIAPELRVGDYIRLAAGPIGQTE--------------LESLLGWfgcpppetPIASVDAG-------TRRLL 471
Cdd:COG4138 71 RAYlsQQQSPPFAMPVFQYLALHQPAGASSEaveqllaqlaealgLEDKLSR--------PLTQLSGGewqrvrlAAVLL 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 472 DVAGAVASRAPVILLDEPAAG--ISYDEAL-KLGERIAAIpatfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPA 548
Cdd:COG4138 143 QVWPTINPEGQLLLLDEPMNSldVAQQAALdRLLRELCQQ----GITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETA 218
|
250
....*....|....*...
gi 492864881 549 EVLDMPEVQKAYmGVDFE 566
Cdd:COG4138 219 EVMTPENLSEVF-GVKFR 235
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
337-545 |
4.40e-19 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 86.09 E-value: 4.40e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGtVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRRt 416
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRRIGYLP- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 wQTTRIAPELRVGDYIRLAAgpigqtelesLLGwfGCPPPE-------------------TPIASVDAGTRRLLDVAGAV 477
Cdd:cd03264 79 -QEFGVYPNFTVREFLDYIA----------WLK--GIPSKEvkarvdevlelvnlgdrakKKIGSLSGGMRRRVGIAQAL 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 478 ASRAPVILLDEPAAGISYDEALKLGERIAAIPATfgSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03264 146 VGDPSILIVDEPTAGLDPEERIRFRNLLSELGED--RIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
337-545 |
5.95e-19 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 85.35 E-value: 5.95e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGK-PLEALSATARAKAGIRR 415
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKsYQKNIEALRRIGALIEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWqttrIAPELRVGDYIRLAAGPIG--QTELESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAG 492
Cdd:cd03268 81 PG----FYPNLTARENLRLLARLLGirKKRIDEVLDVVGLKDsAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNG 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 492864881 493 ISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03268 157 LDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
333-556 |
5.97e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 87.21 E-value: 5.97e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 333 EGTVLEVRDLTVRYGAVT-ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEalsATARAKA 411
Cdd:PRK13636 2 EDYILKVEELNYNYSDGThALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPID---YSRKGLM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 GIRRTWQTTRIAPE---LRVGDYIRLAAGPIG--------QTELESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVAS 479
Cdd:PRK13636 79 KLRESVGMVFQDPDnqlFSASVYQDVSFGAVNlklpedevRKRVDNALKRTGIEHlKDKPTHCLSFGQKKRVAIAGVLVM 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 480 RAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEV 556
Cdd:PRK13636 159 EPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAEKEM 235
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
308-552 |
7.39e-19 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 86.29 E-value: 7.39e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 308 KLFPRRNRQARSAAQALANSAPAigegtvlevrdltvRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP 387
Cdd:COG1134 12 KSYRLYHEPSRSLKELLLRRRRT--------------RREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 388 RYDGTVLLHGK---PLEaLSA------TAR-------AKAGIRRTwQTTRIAPELR----VGDYIrlaagpigqtelesl 447
Cdd:COG1134 78 PTSGRVEVNGRvsaLLE-LGAgfhpelTGReniylngRLLGLSRK-EIDEKFDEIVefaeLGDFI--------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 448 lgwfgcpppETPIASVDAGTR-RLLdVAGAVASRAPVILLDEP-AAGisyDEAL--KLGERIAAIPATfGSAVLLIEHDM 523
Cdd:COG1134 141 ---------DQPVKTYSSGMRaRLA-FAVATAVDPDILLVDEVlAVG---DAAFqkKCLARIRELRES-GRTVIFVSHSM 206
|
250 260
....*....|....*....|....*....
gi 492864881 524 DLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:COG1134 207 GAVRRLCDRAIWLEKGRLVMDGDPEEVIA 235
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
336-554 |
1.49e-18 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 86.65 E-value: 1.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRY----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRY---DGTVLLHGKPLEALSATAR 408
Cdd:COG0444 1 LLEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPgitSGEILFDGEDLLKLSEKEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 409 AKagIRRtwqtTRIA-----------PELRVGDYIR---LAAGPIGQTELE----SLLGWFGCPPPEtpiasvdagtrRL 470
Cdd:COG0444 81 RK--IRG----REIQmifqdpmtslnPVMTVGDQIAeplRIHGGLSKAEAReraiELLERVGLPDPE-----------RR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 471 LD---------------VAGAVASRAPVILLDEPA--------AGIsydeaLKLgerIAAIPATFGSAVLLIEHDMDLVR 527
Cdd:COG0444 144 LDryphelsggmrqrvmIARALALEPKLLIADEPTtaldvtiqAQI-----LNL---LKDLQRELGLAILFITHDLGVVA 215
|
250 260
....*....|....*....|....*..
gi 492864881 528 RACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:COG0444 216 EIADRVAVMYAGRIVEEGPVEELFENP 242
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
336-552 |
1.62e-18 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 86.40 E-value: 1.62e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrr 415
Cdd:PRK13537 7 PIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQRVGV-- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRV-------GDYIRLAAGPIGQ--------TELESllgwfgcpPPETPIASVDAGTRRLLDVAGAVASR 480
Cdd:PRK13537 85 VPQFDNLDPDFTVrenllvfGRYFGLSAAAARAlvppllefAKLEN--------KADAKVGELSGGMKRRLTLARALVND 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 481 APVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:PRK13537 157 PDVLVLDEPTTGLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIE 227
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
335-543 |
4.86e-18 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 83.17 E-value: 4.86e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYG----AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAK 410
Cdd:COG1136 3 PLLELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELAR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 411 agIRRT-----WQTTRIAPELRVGDYIRLAAGPIG------QTELESLLGWFGcpppetpIASvdagtrrLLD------- 472
Cdd:COG1136 83 --LRRRhigfvFQFFNLLPELTALENVALPLLLAGvsrkerRERARELLERVG-------LGD-------RLDhrpsqls 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 473 --------VAGAVASRAPVILLDEPAAgisydeAL--KLGERI----AAIPATFGSAVLLIEHDMDLVRRACTAITVFDf 538
Cdd:COG1136 147 ggqqqrvaIARALVNRPKLILADEPTG------NLdsKTGEEVlellRELNRELGTTIVMVTHDPELAARADRVIRLRD- 219
|
....*
gi 492864881 539 GQVIA 543
Cdd:COG1136 220 GRIVS 224
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
336-556 |
4.96e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 84.47 E-value: 4.96e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRY-GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLealsatarAKAGIR 414
Cdd:PRK13652 3 LIETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPI--------TKENIR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RTWQTTRIAPElRVGDYI-------RLAAGPIG--------QTELESLLGWFGCPPPETPIA-SVDAGTRRLLDVAGAVA 478
Cdd:PRK13652 75 EVRKFVGLVFQ-NPDDQIfsptveqDIAFGPINlgldeetvAHRVSSALHMLGLEELRDRVPhHLSGGEKKRVAIAGVIA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 479 SRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEV 556
Cdd:PRK13652 154 MEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQPDL 231
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
339-542 |
6.44e-18 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 87.04 E-value: 6.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 339 VRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGK----------PL-EALSATA 407
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGlrigylpqepPLdDDLTVLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 408 RAKAGIRRTWQTTR------IAPELRVGDYIRLAAgpiGQTELESLLGW------------FGCP--PPETPIASVDAGT 467
Cdd:COG0488 81 TVLDGDAELRALEAeleeleAKLAEPDEDLERLAE---LQEEFEALGGWeaearaeeilsgLGFPeeDLDRPVSELSGGW 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 468 RRLLDVAGAVASRAPVILLDEP-----AAGISYDEA-LKlgeriaaipaTFGSAVLLIEHDMDLVRRACTAITVFDFGQV 541
Cdd:COG0488 158 RRRVALARALLSEPDLLLLDEPtnhldLESIEWLEEfLK----------NYPGTVLVVSHDRYFLDRVATRILELDRGKL 227
|
.
gi 492864881 542 I 542
Cdd:COG0488 228 T 228
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
335-551 |
7.17e-18 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 83.21 E-value: 7.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFL-PRYDGTVLLHGKPLEALSATA-RAKAG 412
Cdd:COG1119 2 PLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLpPTYGNDVRLFGERRGGEDVWElRKRIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 413 IRRTWQTTRIAPELRVGDYIRLAA-GPIG--------QTEL-ESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVASRA 481
Cdd:COG1119 82 LVSPALQLRFPRDETVLDVVLSGFfDSIGlyreptdeQRERaRELLELLGLAHlADRPFGTLSQGEQRRVLIARALVKDP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 482 PVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVL 551
Cdd:COG1119 162 ELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVL 231
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
156-551 |
1.32e-17 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 86.43 E-value: 1.32e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 156 FLFVLLAYGIIAVVLEFISHSRLGASW-LAVRHSERAA-------------AANGISIPRAKLSAFAISAFISGISGGLL 221
Cdd:COG2274 298 ALVVLLLIPLYVLLGLLFQPRLRRLSReESEASAKRQSllvetlrgietikALGAESRFRRRWENLLAKYLNARFKLRRL 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 222 AGYLGTLvAENFSMMQSLALFAVAT---MAGaHFTLGALIGGVLIVLfpellrRLNLPqdignvffALGAVQALSSGETI 298
Cdd:COG2274 378 SNLLSTL-SGLLQQLATVALLWLGAylvIDG-QLTLGQLIAFNILSG------RFLAP--------VAQLIGLLQRFQDA 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 299 AETWTRLAEKLFPRRNRQARSAAQALANSAPAIgegtvlEVRDLTVRYG--AVTALNKVNLTVPAGTVVGLVGPNGAGKS 376
Cdd:COG2274 442 KIALERLDDILDLPPEREEGRSKLSLPRLKGDI------ELENVSFRYPgdSPPVLDNISLTIKPGERVAIVGRSGSGKS 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 377 TLVDAIAGFLPRYDGTVLLHGKPLEALS--------------------------ATARAKAGIRRTWQTTRIApelRVGD 430
Cdd:COG2274 516 TLLKLLLGLYEPTSGRILIDGIDLRQIDpaslrrqigvvlqdvflfsgtireniTLGDPDATDEEIIEAARLA---GLHD 592
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 431 YI-RLAAGpigqteLESLLGWFGcpppetpiASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIP 509
Cdd:COG2274 593 FIeALPMG------YDTVVGEGG--------SNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLL 658
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 492864881 510 AtfGSAVLLIEHDMDLVRRaCTAITVFDFGQVIASGEPAEVL 551
Cdd:COG2274 659 K--GRTVIIIAHRLSTIRL-ADRIIVLDKGRIVEDGTHEELL 697
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
337-408 |
1.71e-17 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 83.99 E-value: 1.71e-17
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATAR 408
Cdd:COG3842 6 LELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKR 77
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
337-562 |
1.90e-17 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 81.72 E-value: 1.90e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGaVTALNkVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrrt 416
Cdd:COG3840 2 LRLDDLTYRYG-DFPLR-FDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPVSML--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRLAAGPIG------QTELESLLGWFGcpppetpIAsvDAGTRRLLDVAGAVASRA--------- 481
Cdd:COG3840 77 FQENNLFPHLTVAQNIGLGLRPGLkltaeqRAQVEQALERVG-------LA--GLLDRLPGQLSGGQRQRValarclvrk 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 482 -PVILLDEPAAGIsyDEALK--LGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDM--PEV 556
Cdd:COG3840 148 rPILLLDEPFSAL--DPALRqeMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGepPPA 225
|
....*.
gi 492864881 557 QKAYMG 562
Cdd:COG3840 226 LAAYLG 231
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
334-405 |
2.11e-17 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 82.06 E-value: 2.11e-17
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492864881 334 GTVLEVRDLTVRY----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSA 405
Cdd:COG1116 5 APALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGP 80
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
281-522 |
2.28e-17 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 85.10 E-value: 2.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 281 NVFFAL-GAVQALSSGETIAEtwtRLAEKLFPRRNRQARSAAQALANSAPAIGegtvLEVRDLTVRY-GAVTALNKVNLT 358
Cdd:TIGR02868 285 EAFAALpAAAQQLTRVRAAAE---RIVEVLDAAGPVAEGSAPAAGAVGLGKPT----LELRDLSAGYpGAPPVLDGVSLD 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 359 VPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATArakagIRRTWQTTRIAPEL---RVGDYIRLA 435
Cdd:TIGR02868 358 LPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDE-----VRRRVSVCAQDAHLfdtTVRENLRLA 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 436 AGPIGQTELESLLGWFGCPPP--------ETPI----ASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGE 503
Cdd:TIGR02868 433 RPDATDEELWAALERVGLADWlralpdglDTVLgeggARLSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLE 512
|
250
....*....|....*....
gi 492864881 504 RIAAipATFGSAVLLIEHD 522
Cdd:TIGR02868 513 DLLA--ALSGRTVVLITHH 529
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
336-555 |
2.81e-17 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 81.09 E-value: 2.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYG----AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGfLPRYD-GTVLLHGKPLEALSA----T 406
Cdd:cd03258 1 MIELKNVSKVFGdtggKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCING-LERPTsGSVLVDGTDLTLLSGkelrK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 407 ARAK--------------------------AGIRRTWQTTRIAPELR-VGDYIRLAAGPigqtelesllgwfgcpppetp 459
Cdd:cd03258 80 ARRRigmifqhfnllssrtvfenvalpleiAGVPKAEIEERVLELLElVGLEDKADAYP--------------------- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 460 iASVDAGTRRLLDVAGAVASRAPVILLDEPAAGI---SYDEALKLgerIAAIPATFGSAVLLIEHDMDLVRRACTAITVF 536
Cdd:cd03258 139 -AQLSGGQKQRVGIARALANNPKVLLCDEATSALdpeTTQSILAL---LRDINRELGLTIVLITHEMEVVKRICDRVAVM 214
|
250
....*....|....*....
gi 492864881 537 DFGQVIASGEPAEVLDMPE 555
Cdd:cd03258 215 EKGEVVEEGTVEEVFANPQ 233
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
337-529 |
3.03e-17 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 80.61 E-value: 3.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGA----VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKag 412
Cdd:cd03255 1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAA-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 413 IRRT-----WQTTRIAPELRVGDYIRLAAGPIGQTELE------SLLGWFGCPPPET-PIASVDAGTRRLLDVAGAVASR 480
Cdd:cd03255 79 FRRRhigfvFQSFNLLPDLTALENVELPLLLAGVPKKErreraeELLERVGLGDRLNhYPSELSGGQQQRVAIARALAND 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 492864881 481 APVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRA 529
Cdd:cd03255 159 PKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEYA 207
|
|
| sufC |
TIGR01978 |
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ... |
337-436 |
3.99e-17 |
|
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 81.15 E-value: 3.99e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFlPRY---DGTVLLHGKPLEALSATARAKAGI 413
Cdd:TIGR01978 1 LKIKDLHVSVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGH-PSYevtSGTILFKGQDLLELEPDERARAGL 79
|
90 100
....*....|....*....|...
gi 492864881 414 RRTWQTTRIAPELRVGDYIRLAA 436
Cdd:TIGR01978 80 FLAFQYPEEIPGVSNLEFLRSAL 102
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
337-551 |
5.54e-17 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 82.43 E-value: 5.54e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRY----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGfLPRYD-GTVLLHGKPLEALSA----TA 407
Cdd:COG1135 2 IELENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINL-LERPTsGSVLVDGVDLTALSErelrAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 408 RAKAGI---------RRTwqttriapelrVGDYIRLAagpigqteLEsllgwfgcpppetpIASVDAGTRR-----LLD- 472
Cdd:COG1135 81 RRKIGMifqhfnllsSRT-----------VAENVALP--------LE--------------IAGVPKAEIRkrvaeLLEl 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 473 -----------------------VAGAVASRAPVILLDEP--------AAGIsydeaLKLgerIAAIPATFGSAVLLIEH 521
Cdd:COG1135 128 vglsdkadaypsqlsggqkqrvgIARALANNPKVLLCDEAtsaldpetTRSI-----LDL---LKDINRELGLTIVLITH 199
|
250 260 270
....*....|....*....|....*....|
gi 492864881 522 DMDLVRRACTAITVFDFGQVIASGEPAEVL 551
Cdd:COG1135 200 EMDVVRRICDRVAVLENGRIVEQGPVLDVF 229
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
308-545 |
6.96e-17 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 79.88 E-value: 6.96e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 308 KLFPRRNRQARSAAQALANSAPAigegtvlevrdltvRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP 387
Cdd:cd03220 8 KSYPTYKGGSSSLKKLGILGRKG--------------EVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 388 RYDGTVLLHGKPlealSATARAKAGIRrtwqttriaPELRVGDYIRLAAGPIGQTELE-----------SLLGWFGcppp 456
Cdd:cd03220 74 PDSGTVTVRGRV----SSLLGLGGGFN---------PELTGRENIYLNGRLLGLSRKEidekideiiefSELGDFI---- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 457 ETPIASVDAGTRRLLDVAGAVASRAPVILLDEP-AAGisyDEA--LKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAI 533
Cdd:cd03220 137 DLPVKTYSSGMKARLAFAIATALEPDILLIDEVlAVG---DAAfqEKCQRRLRELLKQ-GKTVILVSHDPSSIKRLCDRA 212
|
250
....*....|..
gi 492864881 534 TVFDFGQVIASG 545
Cdd:cd03220 213 LVLEKGKIRFDG 224
|
|
| livM |
PRK11301 |
leucine/isoleucine/valine transporter permease subunit; Provisional |
47-274 |
9.26e-17 |
|
leucine/isoleucine/valine transporter permease subunit; Provisional
Pssm-ID: 236896 [Multi-domain] Cd Length: 419 Bit Score: 82.71 E-value: 9.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 47 LGL--VAGRTGMISLCQMSFAGVGAWVTGYLNLIeapGGLAVWVLL--GGLAAVPVGIAIGLPALRLRGINLAIVTLSFA 122
Cdd:PRK11301 126 LGLnvVVGLAGLLDLGYVGFYAVGAYTYALLNHY---YGLGFWECLpiAGLMAALFGFLLGFPVLRLRGDYLAIVTLGFG 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 123 AAFDTVLATITF--PGQTSFTQVARPDLF-------ASDRG------YF----------LFVLLAYGIIAVVLEFIShSR 177
Cdd:PRK11301 203 EIIRILLLNNTEitGGPNGISQIPKPTLFglefsrtAREGGwdtfheFFglkydpsdrvIFLYLVALLLVVLTLFVI-NR 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 178 L-----GASWLAVRHSERAAAANGISIPRAKLSAFAISAFISGISGGLLAGYLGTLVAENFSMMQSLALFAVATMAGAHF 252
Cdd:PRK11301 282 LlrmplGRAWEALREDEIACRSLGLNPTRIKLSAFTIGAAFAGFAGTFFAARQGFVSPESFTFIESAFILAIVVLGGMGS 361
|
250 260
....*....|....*....|..
gi 492864881 253 TLGALIGGVLIVLFPELLRRLN 274
Cdd:PRK11301 362 QFGVILAAILLVVLPELMRDFN 383
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
334-563 |
9.30e-17 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 80.60 E-value: 9.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 334 GTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAgI 413
Cdd:PRK10575 9 DTTFALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-V 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 RRTWQTTRIAPELRVGDYIrlaagPIGQTELESLLGWFGCPPPE-----------TPIA-----SVDAGTRRLLDVAGAV 477
Cdd:PRK10575 88 AYLPQQLPAAEGMTVRELV-----AIGRYPWHGALGRFGAADREkveeaislvglKPLAhrlvdSLSGGERQRAWIAMLV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 478 ASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEVQ 557
Cdd:PRK10575 163 AQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGETLE 242
|
....*....
gi 492864881 558 KAY---MGV 563
Cdd:PRK10575 243 QIYgipMGI 251
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
345-529 |
1.04e-16 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 78.43 E-value: 1.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 345 RYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPL-----------EALSATARAKAGI 413
Cdd:NF040873 1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARvayvpqrsevpDSLPLTVRDLVAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 -----RRTWQTTRIAPELRVGDyirlAAGPIGQTELEsllgwfgcpppETPIASVDAGTRRLLDVAGAVASRAPVILLDE 488
Cdd:NF040873 81 grwarRGLWRRLTRDDRAAVDD----ALERVGLADLA-----------GRQLGELSGGQRQRALLAQGLAQEADLLLLDE 145
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 492864881 489 PAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRA 529
Cdd:NF040873 146 PTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRA 185
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
337-550 |
1.38e-16 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 82.52 E-value: 1.38e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRRT 416
Cdd:PRK09700 6 ISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLGIGII 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRLAAGPIG-------------QTELESLLGWFGCP-PPETPIASVDAGTRRLLDVAGAVASRAP 482
Cdd:PRK09700 86 YQELSVIDELTVLENLYIGRHLTKkvcgvniidwremRVRAAMMLLRVGLKvDLDEKVANLSISHKQMLEIAKTLMLDAK 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 483 VILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEV 550
Cdd:PRK09700 166 VIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDV 232
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
337-565 |
1.41e-16 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 79.59 E-value: 1.41e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRygavTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPrYDGTVLLHGKPLEALSATARAKagiRRT 416
Cdd:PRK03695 1 MQLNDVAVS----TRLGPLSAEVRAGEILHLVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEAWSAAELAR---HRA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 W--QTTRIAPELRVGDYIRL-----AAGPIGQTELESLLGWFGCPPP-ETPIASVDAGTRRLLDVAGAVASRAPVI---- 484
Cdd:PRK03695 73 YlsQQQTPPFAMPVFQYLTLhqpdkTRTEAVASALNEVAEALGLDDKlGRSVNQLSGGEWQRVRLAAVVLQVWPDInpag 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 485 ---LLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEVQKAYm 561
Cdd:PRK03695 153 qllLLDEPMNSLDVAQQAALDRLLSELCQQ-GIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPENLAQVF- 230
|
....
gi 492864881 562 GVDF 565
Cdd:PRK03695 231 GVNF 234
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
337-555 |
2.19e-16 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 80.58 E-value: 2.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGkplealsatarakagirRT 416
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNG-----------------RD 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVG----DY-------IR--LAAGpigqteLESLlgwfgcPPPEtpiASVDAGTRRLLD----------- 472
Cdd:COG1118 66 LFTNLPPRERRVGfvfqHYalfphmtVAenIAFG------LRVR------PPSK---AEIRARVEELLElvqlegladry 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 473 -------------VAGAVASRAPVILLDEPAAGIsyDEALK------LGERIAAIPATfgsaVLLIEHDMDLVRRACTAI 533
Cdd:COG1118 131 psqlsggqrqrvaLARALAVEPEVLLLDEPFGAL--DAKVRkelrrwLRRLHDELGGT----TVFVTHDQEEALELADRV 204
|
250 260
....*....|....*....|..
gi 492864881 534 TVFDFGQVIASGEPAEVLDMPE 555
Cdd:COG1118 205 VVMNQGRIEQVGTPDEVYDRPA 226
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
338-566 |
2.39e-16 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 78.97 E-value: 2.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 338 EVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKA-GIRRt 416
Cdd:COG4604 3 EIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKRlAILR- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 wQTTRIAPELRVGDYI----------RLaaGPIGQTELESLLGWFGCpppeTPIAsvdagtRRLLD-----------VAG 475
Cdd:COG4604 82 -QENHINSRLTVRELVafgrfpyskgRL--TAEDREIIDEAIAYLDL----EDLA------DRYLDelsggqrqrafIAM 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 476 AVASRAPVILLDEP--------AAGIsydeaLKLGERIAaipATFGSAVLLIEHDMDLVrrACTA--ITVFDFGQVIASG 545
Cdd:COG4604 149 VLAQDTDYVLLDEPlnnldmkhSVQM-----MKLLRRLA---DELGKTVVIVLHDINFA--SCYAdhIVAMKDGRVVAQG 218
|
250 260
....*....|....*....|.
gi 492864881 546 EPAEVLDmPEVQKAYMGVDFE 566
Cdd:COG4604 219 TPEEIIT-PEVLSDIYDTDIE 238
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
337-545 |
3.53e-16 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 77.79 E-value: 3.53e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGA----VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGkpLEALSATARAKAG 412
Cdd:cd03266 2 ITADALTKRFRDvkktVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDG--FDVVKEPAEARRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 413 IRRTWQTTRIAPELRVGDYIRLAAGPIG------QTELESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVASRAPVIL 485
Cdd:cd03266 80 LGFVSDSTGLYDRLTARENLEYFAGLYGlkgdelTARLEELADRLGMEElLDRRVGGFSTGMRQKVAIARALVHDPPVLL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 486 LDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03266 160 LDEPTTGLDVMATRALREFIRQLRAL-GKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
319-529 |
5.53e-16 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 80.79 E-value: 5.53e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 319 SAAQALANSAPA-IGEGTVLEVRDLTVRY-GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLH 396
Cdd:TIGR02857 303 AAPRPLAGKAPVtAAPASSLEFSGVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVN 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 397 GKPLEALSATARAKagiRRTW--QT-----TRIAPELRVG------DYIRLAAGPIGQTELESLLGwfgcPPPETPI--- 460
Cdd:TIGR02857 383 GVPLADADADSWRD---QIAWvpQHpflfaGTIAENIRLArpdasdAEIREALERAGLDEFVAALP----QGLDTPIgeg 455
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 461 -ASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPAtfGSAVLLIEHDMDLVRRA 529
Cdd:TIGR02857 456 gAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAALA 523
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
337-524 |
6.41e-16 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 77.13 E-value: 6.41e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYG----AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSA------- 405
Cdd:cd03293 1 LEVRNVSKTYGggggAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPdrgyvfq 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 406 --------TAR--AKAGIRRTWQTTRIAPElRVGDYIRLaagpIGQTELES-----LLGwfgcpppetpiasvdaGTRRL 470
Cdd:cd03293 81 qdallpwlTVLdnVALGLELQGVPKAEARE-RAEELLEL----VGLSGFENayphqLSG----------------GMRQR 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 492864881 471 LDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMD 524
Cdd:cd03293 140 VALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDID 193
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
336-556 |
6.83e-16 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 78.20 E-value: 6.83e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVT-ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSAT---ARAKA 411
Cdd:PRK13639 1 ILETRDLKYSYPDGTeALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDKKSlleVRKTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 GIrrTWQTTR---IAPelRVGDYIrlAAGPIG----QTELE----------SLLGWFGCPPPEtpiasVDAGTRRLLDVA 474
Cdd:PRK13639 81 GI--VFQNPDdqlFAP--TVEEDV--AFGPLNlglsKEEVEkrvkealkavGMEGFENKPPHH-----LSGGQKKRVAIA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 475 GAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:PRK13639 150 GILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDI 228
|
..
gi 492864881 555 EV 556
Cdd:PRK13639 229 ET 230
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
336-553 |
1.50e-15 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 79.45 E-value: 1.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPR--YDGTVLLHGKPLEALSATARAKAGI 413
Cdd:NF040905 1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHgsYEGEILFDGEVCRFKDIRDSEALGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 RRTWQTTRIAPELRVGDYI-----RLAAGPIG----QTELESLLGWFGCP-PPETPIASVDAGTRRLLDVAGAVASRAPV 483
Cdd:NF040905 81 VIIHQELALIPYLSIAENIflgneRAKRGVIDwnetNRRARELLAKVGLDeSPDTLVTDIGVGKQQLVEIAKALSKDVKL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 484 ILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIasgepaEVLDM 553
Cdd:NF040905 161 LILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGRTI------ETLDC 223
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
337-550 |
1.74e-15 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 75.68 E-value: 1.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP-----RYDGTVLLHGKPLEALSATA---R 408
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgaPDEGEVLLDGKDIYDLDVDVlelR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 409 AKAG----------------------IRRTWqtTRIAPELRVGDYIRLAAGPigqTELESLLGWFGCPPpetpiasvdaG 466
Cdd:cd03260 81 RRVGmvfqkpnpfpgsiydnvayglrLHGIK--LKEELDERVEEALRKAALW---DEVKDRLHALGLSG----------G 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 467 TRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFgsAVLLIEHDMDLVRRACTAITVFDFGQVIASGE 546
Cdd:cd03260 146 QQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKEY--TIVIVTHNMQQAARVADRTAFLLNGRLVEFGP 223
|
....
gi 492864881 547 PAEV 550
Cdd:cd03260 224 TEQI 227
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
332-545 |
3.21e-15 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 75.45 E-value: 3.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 332 GEGTVLEVRDLTVR-YGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGK-PLEalsataRA 409
Cdd:cd03267 16 EPGLIGSLKSLFKRkYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLvPWK------RR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 410 KAGIRRT----WQTTRIAPELRVGDYIRLAAGPIG------QTELESLLGWFGCPPP-ETPIASVDAGTRRLLDVAGAVA 478
Cdd:cd03267 90 KKFLRRIgvvfGQKTQLWWDLPVIDSFYLLAAIYDlpparfKKRLDELSELLDLEELlDTPVRQLSLGQRMRAEIAAALL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 479 SRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03267 170 HEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
336-554 |
6.13e-15 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 76.80 E-value: 6.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAkagIRR 415
Cdd:PRK11607 19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRP---INM 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGDYI-------RLAAGPIGQTELESL----LGWFGCPPPEtpiaSVDAGTRRLLDVAGAVASRAPVI 484
Cdd:PRK11607 96 MFQSYALFPHMTVEQNIafglkqdKLPKAEIASRVNEMLglvhMQEFAKRKPH----QLSGGQRQRVALARSLAKRPKLL 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492864881 485 LLDEPAAGISYdealKLGER----IAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:PRK11607 172 LLDEPMGALDK----KLRDRmqleVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHP 241
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
337-554 |
8.01e-15 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 74.30 E-value: 8.01e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARakaGIRRT 416
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQER---NVGFV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYI-----------RLAAGPIGQTELESL----LGWFGCPPPetpiASVDAGTRRLLDVAGAVASRA 481
Cdd:cd03296 80 FQHYALFRHMTVFDNVafglrvkprseRPPEAEIRAKVHELLklvqLDWLADRYP----AQLSGGQRQRVALARALAVEP 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 482 PVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHD----MDLVRRactaITVFDFGQVIASGEPAEVLDMP 554
Cdd:cd03296 156 KVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDqeeaLEVADR----VVVMNKGRIEQVGTPDEVYDHP 228
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
337-554 |
1.80e-14 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 73.10 E-value: 1.80e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVT-ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATArakagIRR 415
Cdd:cd03295 1 IEFENVTKRYGGGKkAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVE-----LRR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 T----WQTTRIAPELRVGDYIRLaagpigqteLESLLGWfgcpPPETPIASVD----------------------AGTRR 469
Cdd:cd03295 76 KigyvIQQIGLFPHMTVEENIAL---------VPKLLKW----PKEKIRERADellalvgldpaefadryphelsGGQQQ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 470 LLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAE 549
Cdd:cd03295 143 RVGVARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDE 222
|
....*
gi 492864881 550 VLDMP 554
Cdd:cd03295 223 ILRSP 227
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
349-562 |
1.81e-14 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 75.92 E-value: 1.81e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 349 VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRRTWQTTRIAPELRV 428
Cdd:PRK10982 11 VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEALENGISMVHQELNLVLQRSV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 429 GDYIRLAAGPigqtelesLLGWFGCPP------------------PETPIASVDAGTRRLLDVAGAVASRAPVILLDEPA 490
Cdd:PRK10982 91 MDNMWLGRYP--------TKGMFVDQDkmyrdtkaifdeldididPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPT 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 491 AGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASgEPAEVLDMPEVQKAYMG 562
Cdd:PRK10982 163 SSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQWIAT-QPLAGLTMDKIIAMMVG 232
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
337-555 |
1.91e-14 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 73.04 E-value: 1.91e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARakaGIRRT 416
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKR---PVNTV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYI----RLAAGP-----------IGQTELESLLGWFgcpppetpIASVDAGTRRLLDVAGAVASRA 481
Cdd:cd03300 78 FQNYALFPHLTVFENIafglRLKKLPkaeikervaeaLDLVQLEGYANRK--------PSQLSGGQQQRVAIARALVNEP 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 482 PVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHD----MDLVRRactaITVFDFGQVIASGEPAEVLDMPE 555
Cdd:cd03300 150 KVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDqeeaLTMSDR----IAVMNKGKIQQIGTPEEIYEEPA 223
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
337-545 |
3.66e-14 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 71.76 E-value: 3.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGavTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrrt 416
Cdd:cd03298 1 VRLDKIRFSYG--EQPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSML--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIRLAAGP------IGQTELESLLGWFGCPPPETPIA-SVDAGTRRLLDVAGAVASRAPVILLDEP 489
Cdd:cd03298 76 FQENNLFAHLTVEQNVGLGLSPglkltaEDRQAIEVALARVGLAGLEKRLPgELSGGERQRVALARVLVRDKPVLLLDEP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 490 AAgiSYDEALK--LGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03298 156 FA--ALDPALRaeMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
233-404 |
4.42e-14 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 75.20 E-value: 4.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 233 FSMMQSLALFAVATMAGAHFTLGALIGGVLIVLFpELLRRLNLP-QDIGNVFFALGavQALSSGETIAETwtrLAEKlfp 311
Cdd:COG1132 251 MELLGNLGLALVLLVGGLLVLSGSLTVGDLVAFI-LYLLRLFGPlRQLANVLNQLQ--RALASAERIFEL---LDEP--- 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 312 rRNRQARSAAQALANSAPAIgegtvlEVRDLTVRY-GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYD 390
Cdd:COG1132 322 -PEIPDPPGAVPLPPVRGEI------EFENVSFSYpGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTS 394
|
170
....*....|....
gi 492864881 391 GTVLLHGKPLEALS 404
Cdd:COG1132 395 GRILIDGVDIRDLT 408
|
|
| nickel_nikD |
TIGR02770 |
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ... |
355-554 |
4.63e-14 |
|
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 71.63 E-value: 4.63e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 355 VNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP----RYDGTVLLHGKPLEALSATARAKAGIrrtWQTTRIA--PELRV 428
Cdd:TIGR02770 5 LNLSLKRGEVLALVGESGSGKSLTCLAILGLLPpgltQTSGEILLDGRPLLPLSIRGRHIATI---MQNPRTAfnPLFTM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 429 GDYIR---LAAGPIGQTELESLLGWF---GCPPPETPIAS----VDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEA 498
Cdd:TIGR02770 82 GNHAIetlRSLGKLSKQARALILEALeavGLPDPEEVLKKypfqLSGGMLQRVMIALALLLEPPFLIADEPTTDLDVVNQ 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 492864881 499 LKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:TIGR02770 162 ARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNP 217
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
337-526 |
5.05e-14 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 70.98 E-value: 5.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPL-EALSATARA------ 409
Cdd:cd03231 1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLdFQRDSIARGllylgh 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 410 KAGIRrtwqtTRIAPELRVGDYIRLAAGPIGQTELESL-LGWFGcpppETPIASVDAGTRRLLDVAGAVASRAPVILLDE 488
Cdd:cd03231 81 APGIK-----TTLSVLENLRFWHADHSDEQVEEALARVgLNGFE----DRPVAQLSAGQQRRVALARLLLSGRPLWILDE 151
|
170 180 190
....*....|....*....|....*....|....*...
gi 492864881 489 PAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLV 526
Cdd:cd03231 152 PTTALDKAGVARFAEAMAGHCARGGMVVLTTHQDLGLS 189
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
337-531 |
5.66e-14 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 71.28 E-value: 5.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGA-VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEAL--SATARAKAGI 413
Cdd:cd03292 1 IEFINVTKTYPNgTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLrgRAIPYLRRKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 RRTWQTTRIAPELRVGDYIRLAAGPIG------QTELESLLGWFGCPPPETPIAS-VDAGTRRLLDVAGAVASRAPVILL 486
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFALEVTGvppreiRKRVPAALELVGLSHKHRALPAeLSGGEQQRVAIARAIVNSPTILIA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 492864881 487 DEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLV----RRACT 531
Cdd:cd03292 161 DEPTGNLDPDTTWEIMNLLKKINKA-GTTVVVATHAKELVdttrHRVIA 208
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
318-415 |
6.55e-14 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 74.29 E-value: 6.55e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 318 RSAAQALANSAPAIGEgTVLEVRDLTVR-YGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLH 396
Cdd:COG3845 240 REVLLRVEKAPAEPGE-VVLEVENLSVRdDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLD 318
|
90
....*....|....*....
gi 492864881 397 GKPLEALSATARAKAGIRR 415
Cdd:COG3845 319 GEDITGLSPRERRRLGVAY 337
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
336-528 |
9.15e-14 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 70.85 E-value: 9.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRY-GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKagIR 414
Cdd:COG2884 1 MIRFENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPY--LR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RT----WQTTRIAPELRVGDYIRLAAGPIGQTE------LESLLGWFG------CPPPEtpiasVDAGTRRLLDVAGAVA 478
Cdd:COG2884 79 RRigvvFQDFRLLPDRTVYENVALPLRVTGKSRkeirrrVREVLDLVGlsdkakALPHE-----LSGGEQQRVAIARALV 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 492864881 479 SRAPVILLDEPAAGISYD---EALKLGERIAAipatFGSAVLLIEHDMDLVRR 528
Cdd:COG2884 154 NRPELLLADEPTGNLDPEtswEIMELLEEINR----RGTTVLIATHDLELVDR 202
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
335-543 |
1.28e-13 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 73.50 E-value: 1.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIR 414
Cdd:PRK10762 3 ALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKSSQEAGIG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RTWQTTRIAPELRVGDYIRLA---AGPIGQ-------TELESLLGWFGCP-PPETPIASVDAGTRRLLDVAGAVASRAPV 483
Cdd:PRK10762 83 IIHQELNLIPQLTIAENIFLGrefVNRFGRidwkkmyAEADKLLARLNLRfSSDKLVGELSIGEQQMVEIAKVLSFESKV 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 484 ILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIA 543
Cdd:PRK10762 163 IIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDGQFIA 221
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
337-537 |
1.78e-13 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 67.86 E-value: 1.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHgkplealsatarakagirrt 416
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWG-------------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 wQTTRIApelrvgdYIRLAAGpigqtelesllGWfgcpppetpiasvdagTRRLLdVAGAVASRAPVILLDEPAAGISYD 496
Cdd:cd03221 61 -STVKIG-------YFEQLSG-----------GE----------------KMRLA-LAKLLLENPNLLLLDEPTNHLDLE 104
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 492864881 497 --EALklgerIAAIpATFGSAVLLIEHDMDLVRRACTAITVFD 537
Cdd:cd03221 105 siEAL-----EEAL-KEYPGTVILVSHDRYFLDQVATKIIELE 141
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
348-563 |
4.10e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 70.15 E-value: 4.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 348 AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSAT-----ARAKAGIRRTWQTTRI 422
Cdd:PRK13643 18 ASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQkeikpVRKKVGVVFQFPESQL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 423 APELRVGDyirLAAGP----IGQTELESL----LGWFGCPPP--ETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAG 492
Cdd:PRK13643 98 FEETVLKD---VAFGPqnfgIPKEKAEKIaaekLEMVGLADEfwEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAG 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 493 ISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEVQKAY-MGV 563
Cdd:PRK13643 175 LDPKARIEMMQLFESIHQS-GQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQEVDFLKAHeLGV 245
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
335-542 |
5.93e-13 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 69.33 E-value: 5.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRY---------GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSa 405
Cdd:PRK10419 2 TLLNVSGLSHHYahgglsgkhQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLN- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 406 TARAKAgIRRTWQT------TRIAPELRVGDYIR------LAAGPIGQTE-LESLLGWFGCPPP---ETPiASVDAGTRR 469
Cdd:PRK10419 81 RAQRKA-FRRDIQMvfqdsiSAVNPRKTVREIIReplrhlLSLDKAERLArASEMLRAVDLDDSvldKRP-PQLSGGQLQ 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 470 LLDVAGAVASRAPVILLDEpaAGISYDEALKLG--ERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVI 542
Cdd:PRK10419 159 RVCLARALAVEPKLLILDE--AVSNLDLVLQAGviRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIV 231
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
329-547 |
6.76e-13 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 67.82 E-value: 6.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 329 PAIGEgtvLEVRDLTVRYGA--VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGK-----PLE 401
Cdd:cd03369 2 PEHGE---IEVENLSVRYAPdlPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIdistiPLE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 402 ALsataRAKAGIrrtwqttrIA--PELRVGDyIRLAAGPIGQTELESLlgwFGCPPPETPIASVDAGTRRLLDVAGAVAS 479
Cdd:cd03369 79 DL----RSSLTI--------IPqdPTLFSGT-IRSNLDPFDEYSDEEI---YGALRVSEGGLNLSQGQRQLLCLARALLK 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 480 RAPVILLDEPAAGISYDEALKLGEriaAIPATF-GSAVLLIEHDMDLVrRACTAITVFDFGQVIASGEP 547
Cdd:cd03369 143 RPRVLVLDEATASIDYATDALIQK---TIREEFtNSTILTIAHRLRTI-IDYDKILVMDAGEVKEYDHP 207
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
337-410 |
7.84e-13 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 68.57 E-value: 7.84e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 337 LEVRDLTVRYGA-----VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAK 410
Cdd:COG1101 2 LELKNLSKTFNPgtvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAK 80
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
318-413 |
1.63e-12 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 69.66 E-value: 1.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 318 RSAAQALANSAPAIGEgTVLEVRDLTVRygavTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHG 397
Cdd:COG1129 239 RELEDLFPKRAAAPGE-VVLEVEGLSVG----GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDG 313
|
90
....*....|....*.
gi 492864881 398 KPLEALSATARAKAGI 413
Cdd:COG1129 314 KPVRIRSPRDAIRAGI 329
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
335-545 |
2.11e-12 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 67.35 E-value: 2.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRyDGTVLLHgkpLEALSAT----ARAK 410
Cdd:PRK09984 3 TIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITG-DKSAGSH---IELLGRTvqreGRLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 411 AGIRRT-------WQTTRIAPELRVGDYIRLaaGPIGQTEL-ESLLGWFGCPPPETP----------------IASVDAG 466
Cdd:PRK09984 79 RDIRKSrantgyiFQQFNLVNRLSVLENVLI--GALGSTPFwRTCFSWFTREQKQRAlqaltrvgmvhfahqrVSTLSGG 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 467 TRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:PRK09984 157 QQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDG 235
|
|
| TM_PBP1_LivH_like |
cd06582 |
Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two ... |
47-263 |
2.23e-12 |
|
Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.
Pssm-ID: 119324 [Multi-domain] Cd Length: 272 Bit Score: 67.46 E-value: 2.23e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 47 LGLVAGRTGMISLCQMSFAGVGAWVTgYLNLIEAPGGLAVWVLLGGLAAVPVGIAIGLPALRL---RGINLAIVTLSFAA 123
Cdd:cd06582 15 LTLIFGVTGVINFAHGEFYMLGAYVA-YTLLVALGLPFWLALLLALLVAALLGVLLERLVLRPlrgAPLLTLLITFGGLL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 124 AFDTVLATITFPGQTSFTQVARPDLF----ASDRGYFLFVLLAYGIIAVVLE-FISHSRLGASWLAVRHSERAAAANGIS 198
Cdd:cd06582 94 ILLQGLLLIFGGDPRVPPPPLLSGSVelggVTIPPYRLFIIAVALVLLAALYlFLRRTRLGRAIRAVAQNPEAARLLGIN 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 199 IPRAKLSAFAISAFISGISGGLLAGYLGTlvaeNFSMMQSLAL--FAVATMAGAHFTLGALIGGVLI 263
Cdd:cd06582 174 VRRVFALTFALGAALAGLAGVLLAPITGV----SPTMGLLLLLkaFAAVVLGGLGSIPGAVVGGLLL 236
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
337-547 |
2.95e-12 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 66.36 E-value: 2.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRY--GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSatarakagiR 414
Cdd:cd03244 3 IEFKNVSLRYrpNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIG---------L 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RTWQtTRIA-----PELRVGDyIRLAAGPIGQ---------TELESLLGWFGCPPP--ETPIASVD----AGTRRLLDVA 474
Cdd:cd03244 74 HDLR-SRISiipqdPVLFSGT-IRSNLDPFGEysdeelwqaLERVGLKEFVESLPGglDTVVEEGGenlsVGQRQLLCLA 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 475 GAVASRAPVILLDEPAAGISYDEALKLGERIAAipATFGSAVLLIEH------DMDLvrractaITVFDFGQVIASGEP 547
Cdd:cd03244 152 RALLRKSKILVLDEATASVDPETDALIQKTIRE--AFKDCTVLTIAHrldtiiDSDR-------ILVLDKGRVVEFDSP 221
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
335-435 |
3.13e-12 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 66.97 E-value: 3.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFlPRYD---GTVLLHGKPLEALSATARAKA 411
Cdd:CHL00131 6 PILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGH-PAYKileGDILFKGESILDLEPEERAHL 84
|
90 100
....*....|....*....|....
gi 492864881 412 GIRRTWQTTRIAPELRVGDYIRLA 435
Cdd:CHL00131 85 GIFLAFQYPIEIPGVSNADFLRLA 108
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
337-398 |
3.25e-12 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 68.18 E-value: 3.25e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGK 398
Cdd:COG3839 4 LELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGR 65
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
320-560 |
3.47e-12 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 68.94 E-value: 3.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 320 AAQALANSAPaigegTVLEVRDLTVRY-----------GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPr 388
Cdd:COG4172 264 DPRPVPPDAP-----PLLEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP- 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 389 YDGTVLLHGKPLEALSATARAKagIRRTWQttrI---------APELRVGDYIR--LAAGPIGQTELE------SLLGWF 451
Cdd:COG4172 338 SEGEIRFDGQDLDGLSRRALRP--LRRRMQ---VvfqdpfgslSPRMTVGQIIAegLRVHGPGLSAAErrarvaEALEEV 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 452 GCPPpetpiASVD-------AGTRRLLDVAGAVASRAPVILLDEP--------AAGIsydeaLKLgerIAAIPATFGSAV 516
Cdd:COG4172 413 GLDP-----AARHryphefsGGQRQRIAIARALILEPKLLVLDEPtsaldvsvQAQI-----LDL---LRDLQREHGLAY 479
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 492864881 517 LLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPevQKAY 560
Cdd:COG4172 480 LFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAP--QHPY 521
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
335-555 |
3.59e-12 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 68.94 E-value: 3.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGA----VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP----RYDGTVLLHGKPLeaLSAT 406
Cdd:COG4172 5 PLLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPdpaaHPSGSILFDGQDL--LGLS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 407 ARAKAGIRrtwqTTRIA-----------PELRVGDYI-------RLAAGPIGQTELESLLGWFGCPPPETPIAS----VD 464
Cdd:COG4172 83 ERELRRIR----GNRIAmifqepmtslnPLHTIGKQIaevlrlhRGLSGAAARARALELLERVGIPDPERRLDAyphqLS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 465 AGTRRLLDVAGAVASRaPVILL-DEP--------AAGIsydeaLKLgerIAAIPATFGSAVLLIEHDMDLVRRACTAITV 535
Cdd:COG4172 159 GGQRQRVMIAMALANE-PDLLIaDEPttaldvtvQAQI-----LDL---LKDLQRELGMALLLITHDLGVVRRFADRVAV 229
|
250 260
....*....|....*....|
gi 492864881 536 FDFGQVIASGEPAEVLDMPE 555
Cdd:COG4172 230 MRQGEIVEQGPTAELFAAPQ 249
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
338-550 |
4.28e-12 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 67.52 E-value: 4.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 338 EVRDLTVRY----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSAT----ARA 409
Cdd:PRK11153 3 ELKNISKVFpqggRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKelrkARR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 410 KAGI---------RRTwqttriapelrVGDYIRLAagpigqteLEsLLGWfgcpppetPIASVDAGTRRLLDVAG----- 475
Cdd:PRK11153 83 QIGMifqhfnllsSRT-----------VFDNVALP--------LE-LAGT--------PKAEIKARVTELLELVGlsdka 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 476 -------------------AVASRAPVILLDEpaAGISYDEA-----LKLgerIAAIPATFGSAVLLIEHDMDLVRRACT 531
Cdd:PRK11153 135 drypaqlsggqkqrvaiarALASNPKVLLCDE--ATSALDPAttrsiLEL---LKDINRELGLTIVLITHEMDVVKRICD 209
|
250
....*....|....*....
gi 492864881 532 AITVFDFGQVIASGEPAEV 550
Cdd:PRK11153 210 RVAVIDAGRLVEQGTVSEV 228
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
336-558 |
4.30e-12 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 66.27 E-value: 4.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAkagIRR 415
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERL---IRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 ----TWQTTRIAPELRVGDYIrlAAGPI---GQTELES------LLGWFGCP------PPEtpiasVDAGTRRLLDVAGA 476
Cdd:PRK09493 78 eagmVFQQFYLFPHLTALENV--MFGPLrvrGASKEEAekqareLLAKVGLAerahhyPSE-----LSGGQQQRVAIARA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 477 VASRAPVILLDEPAAGISYD---EALKLGERIaaipATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDM 553
Cdd:PRK09493 151 LAVKPKLMLFDEPTSALDPElrhEVLKVMQDL----AEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKN 226
|
....*
gi 492864881 554 PEVQK 558
Cdd:PRK09493 227 PPSQR 231
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
337-552 |
4.58e-12 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 65.97 E-value: 4.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGA--VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLE-ALSATARAKAG- 412
Cdd:cd03252 1 ITFEHVRFRYKPdgPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLAlADPAWLRRQVGv 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 413 -----------IRRTWQTTRIAPEL-RVGDYIRLAAGPIGQTEL----ESLLGWFGcpppetpiASVDAGTRRLLDVAGA 476
Cdd:cd03252 81 vlqenvlfnrsIRDNIALADPGMSMeRVIEAAKLAGAHDFISELpegyDTIVGEQG--------AGLSGGQRQRIAIARA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492864881 477 VASRAPVILLDEPAAGISYDEALKLGERIAAIPAtfGSAVLLIEHDMDLVRRAcTAITVFDFGQVIASGEPAEVLD 552
Cdd:cd03252 153 LIHNPRILIFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTVKNA-DRIIVMEKGRIVEQGSHDELLA 225
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
336-384 |
4.66e-12 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 69.00 E-value: 4.66e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAG 384
Cdd:NF033858 1 VARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAG 49
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
351-550 |
5.79e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 66.61 E-value: 5.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 351 ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATA---RAKAGIrrTWQTtriaPELR 427
Cdd:PRK13637 22 ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKLsdiRKKVGL--VFQY----PEYQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 428 VGD---YIRLAAGPI--GQTELE---------SLLGW-FGCPPPETPIaSVDAGTRRLLDVAGAVASRAPVILLDEPAAG 492
Cdd:PRK13637 96 LFEetiEKDIAFGPInlGLSEEEienrvkramNIVGLdYEDYKDKSPF-ELSGGQKRRVAIAGVVAMEPKILILDEPTAG 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492864881 493 I---SYDEALklgERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEV 550
Cdd:PRK13637 175 LdpkGRDEIL---NKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREV 232
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
337-403 |
1.14e-11 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 63.39 E-value: 1.14e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 337 LEVRDLTVRYGAVTA--LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEAL 403
Cdd:cd03246 1 LEVENVSFRYPGAEPpvLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQW 69
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
337-560 |
1.15e-11 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 65.33 E-value: 1.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIR-- 414
Cdd:PRK11701 7 LSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYALSEAERRrl 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 -RT-WQTTRIAPE--LR--------VGDyiRLAA------GPIGQTELEsllgWFGcpPPETPIASVD-------AGTRR 469
Cdd:PRK11701 87 lRTeWGFVHQHPRdgLRmqvsaggnIGE--RLMAvgarhyGDIRATAGD----WLE--RVEIDAARIDdlpttfsGGMQQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 470 LLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAE 549
Cdd:PRK11701 159 RLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLTDQ 238
|
250
....*....|.
gi 492864881 550 VLDMPevQKAY 560
Cdd:PRK11701 239 VLDDP--QHPY 247
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
327-522 |
1.28e-11 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 65.08 E-value: 1.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 327 SAPAIGEGTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLealsat 406
Cdd:PRK11247 3 NTARLNQGTPLLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPL------ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 407 ARAKAGIRRTWQTTRIAPELRVGDYIRLAAGPIGQTELESLLGWFGCPP--PETPiASVDAGTRRLLDVAGAVASRAPVI 484
Cdd:PRK11247 77 AEAREDTRLMFQDARLLPWKKVIDNVGLGLKGQWRDAALQALAAVGLADraNEWP-AALSGGQKQRVALARALIHRPGLL 155
|
170 180 190
....*....|....*....|....*....|....*...
gi 492864881 485 LLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHD 522
Cdd:PRK11247 156 LLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHD 193
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
336-559 |
1.30e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 65.14 E-value: 1.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVT-ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSAT-ARAKAGI 413
Cdd:PRK13647 4 IIEVEDLHFRYKDGTkALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKwVRSKVGL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 -----------RRTWQTTRIAP----------ELRVGDYIRLaagpIGQTELEsllgwfgcpppETPIASVDAGTRRLLD 472
Cdd:PRK13647 84 vfqdpddqvfsSTVWDDVAFGPvnmgldkdevERRVEEALKA----VRMWDFR-----------DKPPYHLSYGQKKRVA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 473 VAGAVASRAPVILLDEPAAGIsyDEALKlgERIAAIPATF---GSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAE 549
Cdd:PRK13647 149 IAGVLAMDPDVIVLDEPMAYL--DPRGQ--ETLMEILDRLhnqGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSL 224
|
250
....*....|
gi 492864881 550 VLDMPEVQKA 559
Cdd:PRK13647 225 LTDEDIVEQA 234
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
335-555 |
1.33e-11 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 64.75 E-value: 1.33e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVL-------------LHGKPLE 401
Cdd:PRK09544 3 SLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKrngklrigyvpqkLYLDTTL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 402 ALSAT--ARAKAGIRRtwqtTRIAPELRvgdyiRLAAGPIGQTELESLLGwfgcpppetpiasvdAGTRRLLdVAGAVAS 479
Cdd:PRK09544 83 PLTVNrfLRLRPGTKK----EDILPALK-----RVQAGHLIDAPMQKLSG---------------GETQRVL-LARALLN 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492864881 480 RAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDfGQVIASGEPAEVLDMPE 555
Cdd:PRK09544 138 RPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLN-HHICCSGTPEVVSLHPE 212
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
337-548 |
1.52e-11 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 64.72 E-value: 1.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSatarAKAGIrrT 416
Cdd:PRK11248 2 LQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPG----AERGV--V 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYI----RLAAGPIGQTELESL-------LGWFGcpppETPIASVDAGTRRLLDVAGAVASRAPVIL 485
Cdd:PRK11248 76 FQNEGLLPWRNVQDNVafglQLAGVEKMQRLEIAHqmlkkvgLEGAE----KRYIWQLSGGQRQRVGIARALAANPQLLL 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492864881 486 LDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDM--------DLVRRACTAITV-----FDFGQVIASGEPA 548
Cdd:PRK11248 152 LDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIeeavfmatELVLLSPGPGRVverlpLNFARRFVAGESS 227
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
336-492 |
2.77e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 62.97 E-value: 2.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALS-ATARAKAGIR 414
Cdd:PRK13539 2 MLEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDvAEACHYLGHR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RTwqttrIAPELRVGDYIRLAAGPIGQTEL--ESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAA 491
Cdd:PRK13539 82 NA-----MKPALTVAENLEFWAAFLGGEELdiAAALEAVGLAPlAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTA 156
|
.
gi 492864881 492 G 492
Cdd:PRK13539 157 A 157
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
351-547 |
3.22e-11 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 66.58 E-value: 3.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 351 ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrrTWQTTRIAPELRVGD 430
Cdd:TIGR01257 945 AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLDAVRQSLGM--CPQHNILFHHLTVAE 1022
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 431 YIRLAAGPIG------QTELESLLGWFGCPPPETPIA-SVDAGTRRLLDVAGAVASRAPVILLDEPAAGIS-------YD 496
Cdd:TIGR01257 1023 HILFYAQLKGrsweeaQLEMEAMLEDTGLHHKRNEEAqDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDpysrrsiWD 1102
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 492864881 497 EALKLGEriaaipatfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEP 547
Cdd:TIGR01257 1103 LLLKYRS---------GRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
342-560 |
3.26e-11 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 63.85 E-value: 3.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 342 LTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAgIRRTWQTTR 421
Cdd:PRK10253 13 LTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARR-IGLLAQNAT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 422 IAPELRVGDYI---RLAAGPI---GQTELESLLGWFGCPPPETPIA--SVD---AGTRRLLDVAGAVASRAPVILLDEPA 490
Cdd:PRK10253 92 TPGDITVQELVargRYPHQPLftrWRKEDEEAVTKAMQATGITHLAdqSVDtlsGGQRQRAWIAMVLAQETAIMLLDEPT 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 491 AGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEVQKAY 560
Cdd:PRK10253 172 TWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIY 241
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
337-551 |
4.77e-11 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 64.35 E-value: 4.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVrDLTVRYGAvTALNkVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGkplealsatarakagirRT 416
Cdd:COG4148 3 LEV-DFRLRRGG-FTLD-VDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGG-----------------EV 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTR----IAPELRvgdyirlaagPIG---QtelESLL------------GWFGCPPPETPIaSVDA-----GTRRLLD 472
Cdd:COG4148 63 LQDSArgifLPPHRR----------RIGyvfQ---EARLfphlsvrgnllyGRKRAPRAERRI-SFDEvvellGIGHLLD 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 473 -------------VA-G-AVASRAPVILLDEPAAGIsyDEALKLG-----ERIA---AIPatfgsaVLLIEHDMDLVRRA 529
Cdd:COG4148 129 rrpatlsggerqrVAiGrALLSSPRLLLMDEPLAAL--DLARKAEilpylERLRdelDIP------ILYVSHSLDEVARL 200
|
250 260
....*....|....*....|..
gi 492864881 530 CTAITVFDFGQVIASGEPAEVL 551
Cdd:COG4148 201 ADHVVLLEQGRVVASGPLAEVL 222
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
335-555 |
5.17e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 63.01 E-value: 5.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFL-----PRYDGTVLLHGKPLEALSATARA 409
Cdd:PRK14247 2 NKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIelypeARVSGEVYLDGQDIFKMDVIELR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 410 KAgIRRTWQTTRIAPELRVgdYIRLAAGPI------GQTELESLLGWFGCPPP---------ETPIASVDAGTRRLLDVA 474
Cdd:PRK14247 82 RR-VQMVFQIPNPIPNLSI--FENVALGLKlnrlvkSKKELQERVRWALEKAQlwdevkdrlDAPAGKLSGGQQQRLCIA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 475 GAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFgsAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:PRK14247 159 RALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDM--TIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNP 236
|
.
gi 492864881 555 E 555
Cdd:PRK14247 237 R 237
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
336-551 |
7.29e-11 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 64.82 E-value: 7.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRY-----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLH--------GKPLEA 402
Cdd:TIGR03269 279 IIKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvgdewvdmTKPGPD 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 403 LSATARAKAGI---------RRTW---QTTRIAPEL-----RVGDYIRLAAGPIGQTELESLLgwfgcppPETPiASVDA 465
Cdd:TIGR03269 359 GRGRAKRYIGIlhqeydlypHRTVldnLTEAIGLELpdelaRMKAVITLKMVGFDEEKAEEIL-------DKYP-DELSE 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 466 GTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:TIGR03269 431 GERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIG 510
|
....*.
gi 492864881 546 EPAEVL 551
Cdd:TIGR03269 511 DPEEIV 516
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
334-492 |
9.02e-11 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 61.41 E-value: 9.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 334 GTVLEVRDLTV------RYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFL--PRYDGTVLLHGKPLEALSa 405
Cdd:cd03213 1 GVTLSFRNLTVtvksspSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRtgLGVSGEVLINGRPLDKRS- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 406 tarAKAGIRRTWQTTRIAPELRVGDYIRLAAgpigqtELESLLGwfgcpppetpiasvdaGTRRLLDVAGAVASRAPVIL 485
Cdd:cd03213 80 ---FRKIIGYVPQDDILHPTLTVRETLMFAA------KLRGLSG----------------GERKRVSIALELVSNPSLLF 134
|
....*..
gi 492864881 486 LDEPAAG 492
Cdd:cd03213 135 LDEPTSG 141
|
|
| LivH |
COG0559 |
Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport ... |
42-263 |
1.05e-10 |
|
Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440325 [Multi-domain] Cd Length: 290 Bit Score: 62.77 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 42 IALQSLG--LVAGRTGMISLCQMSFAGVGAWVTGYLNlieAPGGLAVWV--LLGGLAAVPVGIAIGLPALR-LRG---IN 113
Cdd:COG0559 18 YALIALGltLIFGVMGVINFAHGEFVMLGAYVAYTLA---TLLGLPLWLalLLAVLVAALLGVLLERLVIRpLRGappLA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 114 LAIVTLSFAAAFDTVLATITFPGQTSFTQVARPDL---FASDRGYFLFVLLAYGIIAVVLE-FISHSRLGASWLAVRHSE 189
Cdd:COG0559 95 LLLATIGLSLVLQGLVLLIFGADPRSFPALLSGSVelgGVSIPAYRLFIIVVALVLLAALWlFLRRTRLGLAMRAVAQNR 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492864881 190 RAAAANGISIPRAKLSAFAISAFISGISGGLLAGYLGTlvaeNFSMMQSLAL--FAVATMAGAHFTLGALIGGVLI 263
Cdd:COG0559 175 EAARLMGINVDRVIALTFALGAALAGLAGVLLAPIYSV----SPTMGFLLGLkaFAAVVLGGLGSIPGAVVGGLLL 246
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
337-545 |
1.05e-10 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 61.84 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGA--VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALS-ATARAKAGI 413
Cdd:cd03245 3 IEFRNVSFSYPNqeIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDpADLRRNIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 rrTWQTTR-IAPELRvgDYIRLAAGPIGQTELESLLGWFGCPP-----P---ETPI----ASVDAGTRRLLDVAGAVASR 480
Cdd:cd03245 83 --VPQDVTlFYGTLR--DNITLGAPLADDERILRAAELAGVTDfvnkhPnglDLQIgergRGLSGGQRQAVALARALLND 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 481 APVILLDEPAAGISYDEALKLGERIAAIPAtfGSAVLLIEHDM---DLVRRactaITVFDFGQVIASG 545
Cdd:cd03245 159 PPILLLDEPTSAMDMNSEERLKERLRQLLG--DKTLIIITHRPsllDLVDR----IIVMDSGRIVADG 220
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
337-554 |
1.25e-10 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 61.58 E-value: 1.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNkVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrrt 416
Cdd:cd03299 1 LKVENLSKDWKEFKLKN-VSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDISYV--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYIrlAAGPIGQTElesllgwfgcPPPETP-----IASVdAGTRRLLD---------------VAGA 476
Cdd:cd03299 77 PQNYALFPHMTVYKNI--AYGLKKRKV----------DKKEIErkvleIAEM-LGIDHLLNrkpetlsggeqqrvaIARA 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 477 VASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:cd03299 144 LVVNPKILLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKP 221
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
336-556 |
1.36e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 62.42 E-value: 1.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRY---GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLealsaTARAKAG 412
Cdd:PRK13642 4 ILEVENLVFKYekeSDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELL-----TAENVWN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 413 IRRTWQTTRIAPELR-VGDYIR--LAAG----PIGQTEL-----ESLLGWFGCPPPETPIASVDAGTRRLLDVAGAVASR 480
Cdd:PRK13642 79 LRRKIGMVFQNPDNQfVGATVEddVAFGmenqGIPREEMikrvdEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 481 APVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRAcTAITVFDFGQVIASGEPAEVL----DMPEV 556
Cdd:PRK13642 159 PEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAASS-DRILVMKAGEIIKEAAPSELFatseDMVEI 237
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
351-552 |
1.38e-10 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 61.47 E-value: 1.38e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 351 ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALS-ATARAKAGI--RRTW--QTTrIAPE 425
Cdd:cd03254 18 VLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISrKSLRSMIGVvlQDTFlfSGT-IMEN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 426 LRVG------DYIRLAAGPIGQTE--------LESLLGWFGcpppetpiASVDAGTRRLLDVAGAVASRAPVILLDEPAA 491
Cdd:cd03254 97 IRLGrpnatdEEVIEAAKEAGAHDfimklpngYDTVLGENG--------GNLSQGERQLLAIARAMLRDPKILILDEATS 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492864881 492 GISYDEALKLGERIAAIpaTFGSAVLLIEHDMDLVRRAcTAITVFDFGQVIASGEPAEVLD 552
Cdd:cd03254 169 NIDTETEKLIQEALEKL--MKGRTSIIIAHRLSTIKNA-DKILVLDDGKIIEEGTHDELLA 226
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
337-541 |
1.44e-10 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 61.01 E-value: 1.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGfLPRYD-GTVLLHGKPL---EALSATARAKAG 412
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINL-LEEPDsGTIIIDGLKLtddKKNINELRQKVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 413 IrrTWQTTRIAPELRVGDYIRLAagPI---------GQTELESLLGWFGCPPPET--PiASVDAGTRRLLDVAGAVASRA 481
Cdd:cd03262 80 M--VFQQFNLFPHLTVLENITLA--PIkvkgmskaeAEERALELLEKVGLADKADayP-AQLSGGQQQRVAIARALAMNP 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 482 PVILLDEPAAGIS---YDEALKLGERIAAIpatfGSAVLLIEHDMDLVRRACTAITVFDFGQV 541
Cdd:cd03262 155 KVMLFDEPTSALDpelVGEVLDVMKDLAEE----GMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
302-537 |
1.63e-10 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 63.80 E-value: 1.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 302 WTRLAEKlfprrNRQARSAA-----QALANSA---------------PAIGeGTVLEVRDLTVRYGAVTALNKVNLTVPA 361
Cdd:TIGR03719 274 WVRQSPK-----GRQAKSKArlaryEELLSQEfqkrnetaeiyippgPRLG-DKVIEAENLTKAFGDKLLIDDLSFKLPP 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 362 GTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLhGKPLEaLSATARAKAGI---RRTWQttriapELRVG-DYIRlaag 437
Cdd:TIGR03719 348 GGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETVK-LAYVDQSRDALdpnKTVWE------EISGGlDIIK---- 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 438 pIGQTELES--LLGWFGC--PPPETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPatfG 513
Cdd:TIGR03719 416 -LGKREIPSraYVGRFNFkgSDQQKKVGQLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVETLRALEEALLNFA---G 491
|
250 260
....*....|....*....|....
gi 492864881 514 SAVlLIEHDMDLVRRACTAITVFD 537
Cdd:TIGR03719 492 CAV-VISHDRWFLDRIATHILAFE 514
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
354-545 |
1.83e-10 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 60.77 E-value: 1.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 354 KVNLTVPAGtVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEA------LSATARakaGIRRTWQTTRIAPELR 427
Cdd:cd03297 16 KIDFDLNEE-VTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDsrkkinLPPQQR---KIGLVFQQYALFPHLN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 428 VGDYIRLAAGPIGQTEL----ESLLGWFGCPP-PETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAGIsyDEALKLG 502
Cdd:cd03297 92 VRENLAFGLKRKRNREDrisvDELLDLLGLDHlLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSAL--DRALRLQ 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 492864881 503 ERI--AAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:cd03297 170 LLPelKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
336-554 |
2.42e-10 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 61.25 E-value: 2.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVrYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP----RYDGTVLLHGKPLEALSATARAKA 411
Cdd:PRK10418 4 QIELRNIAL-QAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPagvrQTAGRVLLDGKPVAPCALRGRKIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 GIrrtWQTTRIA--PELRVGDYIR---LAAG-PIGQTELESLLGWFGCPPPETPIAS----VDAGTRRLLDVAGAVASRA 481
Cdd:PRK10418 83 TI---MQNPRSAfnPLHTMHTHARetcLALGkPADDATLTAALEAVGLENAARVLKLypfeMSGGMLQRMMIALALLCEA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 482 PVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:PRK10418 160 PFIIADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAP 232
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
337-545 |
2.54e-10 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 59.63 E-value: 2.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYG--AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIr 414
Cdd:cd03247 1 LSINNVSFSYPeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSLISV- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 rtwqttriapelrVGDYIRLAAGPIGQTELESLLGwfgcpppetpiasvdaGTRRLLDVAGAVASRAPVILLDEPAAGIS 494
Cdd:cd03247 80 -------------LNQRPYLFDTTLRNNLGRRFSG----------------GERQRLALARILLQDAPIVLLDEPTVGLD 130
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 492864881 495 YDEALKLGERIAAipATFGSAVLLIEHDMDLVRRAcTAITVFDFGQVIASG 545
Cdd:cd03247 131 PITERQLLSLIFE--VLKDKTLIWITHHLTGIEHM-DKILFLENGKIIMQG 178
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
337-398 |
2.57e-10 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 60.35 E-value: 2.57e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGK 398
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGR 62
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
340-568 |
2.58e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 61.57 E-value: 2.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 340 RDLTVRYGAVT-----ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLL---------HGKPLEALsa 405
Cdd:PRK13634 6 QKVEHRYQYKTpferrALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIgervitagkKNKKLKPL-- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 406 taRAKAGIRRTWQTTRIAPELRVGDyirLAAGPI--GQTELES------LLGWFGCPPP---ETPIAsVDAGTRRLLDVA 474
Cdd:PRK13634 84 --RKKVGIVFQFPEHQLFEETVEKD---ICFGPMnfGVSEEDAkqkareMIELVGLPEEllaRSPFE-LSGGQMRRVAIA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 475 GAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEV---- 550
Cdd:PRK13634 158 GVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIfadp 237
|
250 260 270
....*....|....*....|....*....|.
gi 492864881 551 -------LDMPEVQK------AYMGVDFEEA 568
Cdd:PRK13634 238 deleaigLDLPETVKfkraleEKFGISFPKP 268
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
332-550 |
2.75e-10 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 62.06 E-value: 2.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 332 GEGTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTlvdaiaGFLPRYDGTVLLHGKPLEALSATARAKA 411
Cdd:NF000106 9 GARNAVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**R------GALPAHV*GPDAGRRPWRF*TWCANRRA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 gIRRTWQTTRIAPELR------------VGDYIRLAAGPiGQTELESLLGWFGCPPPE-TPIASVDAGTRRLLDVAGAVA 478
Cdd:NF000106 83 -LRRTIG*HRPVR*GRresfsgrenlymIGR*LDLSRKD-ARARADELLERFSLTEAAgRAAAKYSGGMRRRLDLAASMI 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 479 SRAPVILLDEPAAGISYDEALKLGERIAAIpATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEV 550
Cdd:NF000106 161 GRPAVLYLDEPTTGLDPRTRNEVWDEVRSM-VRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
327-528 |
2.89e-10 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 60.95 E-value: 2.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 327 SAPAIGEGTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLV-------DAIAGFlpRYDGTVLLHGKP 399
Cdd:PRK14243 1 TSTLNGTETVLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILrcfnrlnDLIPGF--RVEGKVTFHGKN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 400 LEALS---ATARAKAGIrrTWQT---------TRIAPELRV----GDYIRLAAGPIGQT----ELESLLGWFGcpppetp 459
Cdd:PRK14243 79 LYAPDvdpVEVRRRIGM--VFQKpnpfpksiyDNIAYGARIngykGDMDELVERSLRQAalwdEVKDKLKQSG------- 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 460 iASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFgsAVLLIEHDMDLVRR 528
Cdd:PRK14243 150 -LSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAAR 215
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
335-548 |
3.85e-10 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 62.52 E-value: 3.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTalnkvnLTVPAGT-----VVGLVGPNGAGKSTLVDAIAGFLPRYDGTVL----LHGKPlealsa 405
Cdd:PRK13409 339 TLVEYPDLTKKLGDFS------LEVEGGEiyegeVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDpelkISYKP------ 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 406 tarakagirrtwQTTRIAPELRVGDYIRLAAGPIG----QTE------LESLLgwfgcpppETPIASVDAGTRRLLDVAG 475
Cdd:PRK13409 407 ------------QYIKPDYDGTVEDLLRSITDDLGssyyKSEiikplqLERLL--------DKNVKDLSGGELQRVAIAA 466
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492864881 476 AVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHD---MDLVrraCTAITVFDfgqviasGEPA 548
Cdd:PRK13409 467 CLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHDiymIDYI---SDRLMVFE-------GEPG 532
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
339-563 |
4.82e-10 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 60.67 E-value: 4.82e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 339 VRDLTVRY-GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPL-EALSATARAKagIRRT 416
Cdd:PRK15056 9 VNDVTVTWrNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTrQALQKNLVAY--VPQS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELrVGDYIRLaaGPIGQteleslLGWFGCPPP------ETPIASVD-------------AGTRRLLDVAGAV 477
Cdd:PRK15056 87 EEVDWSFPVL-VEDVVMM--GRYGH------MGWLRRAKKrdrqivTAALARVDmvefrhrqigelsGGQKKRVFLARAI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 478 ASRAPVILLDEPAAGISydeaLKLGERIAAIPATF---GSAVLLIEHDMDLVRRACTaITVFDFGQVIASGEPAEVLDMP 554
Cdd:PRK15056 158 AQQGQVILLDEPFTGVD----VKTEARIISLLRELrdeGKTMLVSTHNLGSVTEFCD-YTVMVKGTVLASGPTETTFTAE 232
|
....*....
gi 492864881 555 EVQKAYMGV 563
Cdd:PRK15056 233 NLELAFSGV 241
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
337-397 |
4.96e-10 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 59.94 E-value: 4.96e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 337 LEVRDLTVRYG--AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDaiagFLPR-YD---GTVLLHG 397
Cdd:cd03251 1 VEFKNVTFRYPgdGPPVLRDISLDIPAGETVALVGPSGSGKSTLVN----LIPRfYDvdsGRILIDG 63
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
351-556 |
5.05e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 60.79 E-value: 5.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 351 ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIRRTWQTTRIAPELRV-G 429
Cdd:PRK13645 26 ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPANLKKIKEVKRLRKEIGLVFQFPEYQLfQ 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 430 DYIR--LAAGPI--GQTELES------LLGWFGCP---PPETPIaSVDAGTRRLLDVAGAVASRAPVILLDEPAAGIS-- 494
Cdd:PRK13645 106 ETIEkdIAFGPVnlGENKQEAykkvpeLLKLVQLPedyVKRSPF-ELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDpk 184
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 495 -YDEALKLGERIAAipaTFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEV 556
Cdd:PRK13645 185 gEEDFINLFERLNK---EYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSNQEL 244
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
316-549 |
5.16e-10 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 62.17 E-value: 5.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 316 QARSAAQALAN------SAPAIGEGTV-------LEVRDLTVR-YGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDA 381
Cdd:PRK11174 316 QAVGAAESLVTfletplAHPQQGEKELasndpvtIEAEDLEILsPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNA 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 382 IAGFLPrYDGTVLLHGKPLEALSATarakagirrTWQTTrIA-----PELRVG---DYIRLAAGPIGQTELESLL----- 448
Cdd:PRK11174 396 LLGFLP-YQGSLKINGIELRELDPE---------SWRKH-LSwvgqnPQLPHGtlrDNVLLGNPDASDEQLQQALenawv 464
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 449 ---------GWfgcpppETPI----ASVDAGTRRLLDVAGAVASRAPVILLDEPAAgiSYD--------EALKlgeriaa 507
Cdd:PRK11174 465 seflpllpqGL------DTPIgdqaAGLSVGQAQRLALARALLQPCQLLLLDEPTA--SLDahseqlvmQALN------- 529
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 492864881 508 iPATFGSAVLLIEHDMDLVrRACTAITVFDFGQVIASGEPAE 549
Cdd:PRK11174 530 -AASRRQTTLMVTHQLEDL-AQWDQIWVMQDGQIVQQGDYAE 569
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
350-570 |
5.91e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 60.49 E-value: 5.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 350 TALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSAT--ARAKAGIRRTWQTTRIAPELR 427
Cdd:PRK13633 24 LALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENLwdIRNKAGMVFQNPDNQIVATIV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 428 VGDyirLAAGPigqtelESLlgwfGCPPPETPiASVD--------------------AGTRRLLDVAGAVASRAPVILLD 487
Cdd:PRK13633 104 EED---VAFGP------ENL----GIPPEEIR-ERVDeslkkvgmyeyrrhaphllsGGQKQRVAIAGILAMRPECIIFD 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 488 EPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRAcTAITVFDFGQVIASGEPAEVLDMPEVQKAyMGVDFEE 567
Cdd:PRK13633 170 EPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVEA-DRIIVMDSGKVVMEGTPKEIFKEVEMMKK-IGLDVPQ 247
|
...
gi 492864881 568 AAE 570
Cdd:PRK13633 248 VTE 250
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
336-528 |
8.02e-10 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 59.41 E-value: 8.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYG----AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKA 411
Cdd:PRK10584 6 IVEVHHLKKSVGqgehELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 GIRR---TWQTTRIAPELRVGDYIRLAAGPIGQTELES------LLGWFGCPPPETPI-ASVDAGTRRLLDVAGAVASRA 481
Cdd:PRK10584 86 RAKHvgfVFQSFMLIPTLNALENVELPALLRGESSRQSrngakaLLEQLGLGKRLDHLpAQLSGGEQQRVALARAFNGRP 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 492864881 482 PVILLDEPAAGISYdealKLGERIA----AIPATFGSAVLLIEHDMDLVRR 528
Cdd:PRK10584 166 DVLFADEPTGNLDR----QTGDKIAdllfSLNREHGTTLILVTHDLQLAAR 212
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
333-554 |
8.18e-10 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 60.03 E-value: 8.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 333 EGTVLEVRDLTVRY--GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPL-EALSATARA 409
Cdd:PRK13635 2 KEEIIRVEHISFRYpdAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLsEETVWDVRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 410 KAGIrrTWQT-------TRIAPELRVG---------DYIRLAAGPIGQTELESLLgwfgcppPETPiASVDAGTRRLLDV 473
Cdd:PRK13635 82 QVGM--VFQNpdnqfvgATVQDDVAFGlenigvpreEMVERVDQALRQVGMEDFL-------NREP-HRLSGGQKQRVAI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 474 AGAVASRAPVILLDEPAA---GISYDEALklgERIAAIPATFGSAVLLIEHDMDLVRRAcTAITVFDFGQVIASGEPAEV 550
Cdd:PRK13635 152 AGVLALQPDIIILDEATSmldPRGRREVL---ETVRQLKEQKGITVLSITHDLDEAAQA-DRVIVMNKGEILEEGTPEEI 227
|
250
....*....|....*
gi 492864881 551 -----------LDMP 554
Cdd:PRK13635 228 fksghmlqeigLDVP 242
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
333-562 |
8.58e-10 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 59.51 E-value: 8.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 333 EGTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAG 412
Cdd:PRK11614 2 EKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 413 I------RRTWQTTRIAPELRVGDYirLAAGPIGQTELESLLGWFgcpPPETPIASVDAGT-----RRLLDVAGAVASRA 481
Cdd:PRK11614 82 VaivpegRRVFSRMTVEENLAMGGF--FAERDQFQERIKWVYELF---PRLHERRIQRAGTmsggeQQMLAIGRALMSQP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 482 PVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPEVQKAYM 561
Cdd:PRK11614 157 RLLLLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLANEAVRSAYL 235
|
.
gi 492864881 562 G 562
Cdd:PRK11614 236 G 236
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
337-554 |
1.25e-09 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 59.74 E-value: 1.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRY----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP---RYDGTVLLHGKPLEALSATA-- 407
Cdd:PRK09473 13 LDVKDLRVTFstpdGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAangRIGGSATFNGREILNLPEKEln 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 408 --RAKAgIRRTWQ--TTRIAPELRVGDYIrlaagpigqteLESLLGWFGCPPPETPIASV---DA--------------- 465
Cdd:PRK09473 93 klRAEQ-ISMIFQdpMTSLNPYMRVGEQL-----------MEVLMLHKGMSKAEAFEESVrmlDAvkmpearkrmkmyph 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 466 ----GTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQV 541
Cdd:PRK09473 161 efsgGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 240
|
250
....*....|...
gi 492864881 542 IASGEPAEVLDMP 554
Cdd:PRK09473 241 MEYGNARDVFYQP 253
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
351-563 |
1.78e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 58.85 E-value: 1.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 351 ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGkpleaLSATARAK-AGIRRTWQTTRIAPELR-V 428
Cdd:PRK13644 17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSG-----IDTGDFSKlQGIRKLVGIVFQNPETQfV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 429 GDYIR--LAAGP----IGQTEL---------ESLLGWFGCPPPETpiasVDAGTRRLLDVAGAVASRAPVILLDEPAAGI 493
Cdd:PRK13644 92 GRTVEedLAFGPenlcLPPIEIrkrvdralaEIGLEKYRHRSPKT----LSGGQGQCVALAGILTMEPECLIFDEVTSML 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 494 SYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRAcTAITVFDFGQVIASGEPAEVLDMPEVQkaYMGV 563
Cdd:PRK13644 168 DPDSGIAVLERIKKLHEK-GKTIVYITHNLEELHDA-DRIIVMDRGKIVLEGEPENVLSDVSLQ--TLGL 233
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
227-404 |
1.83e-09 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 60.50 E-value: 1.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 227 TLVAENFSMMQSLALFAVATMAGA----HFTLGALIG-GVLIVlFPELLRRLNLP-------QDIGNvffalgavQALSS 294
Cdd:PRK10790 244 TLRLDGFLLRPLLSLFSALILCGLlmlfGFSASGTIEvGVLYA-FISYLGRLNEPlielttqQSMLQ--------QAVVA 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 295 GETIAETWTRlaeklfPRrnrqarsaaQALANSAPAIGEGTVlEVRDLTVRYGA-VTALNKVNLTVPAGTVVGLVGPNGA 373
Cdd:PRK10790 315 GERVFELMDG------PR---------QQYGNDDRPLQSGRI-DIDNVSFAYRDdNLVLQNINLSVPSRGFVALVGHTGS 378
|
170 180 190
....*....|....*....|....*....|.
gi 492864881 374 GKSTLVDAIAGFLPRYDGTVLLHGKPLEALS 404
Cdd:PRK10790 379 GKSTLASLLMGYYPLTEGEIRLDGRPLSSLS 409
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
336-521 |
2.21e-09 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 57.27 E-value: 2.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIrr 415
Cdd:PRK13540 1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLCTYQKQLCF-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGDY----IRLAAGPIGQTELESL--LGWFgcppPETPIASVDAGTRRLLDVAGAVASRAPVILLDEP 489
Cdd:PRK13540 79 VGHRSGINPYLTLRENclydIHFSPGAVGITELCRLfsLEHL----IDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEP 154
|
170 180 190
....*....|....*....|....*....|..
gi 492864881 490 AAGISYDEALKLGERIAAIPATfGSAVLLIEH 521
Cdd:PRK13540 155 LVALDELSLLTIITKIQEHRAK-GGAVLLTSH 185
|
|
| TM_PBP1_transp_AraH_like |
cd06579 |
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ... |
54-286 |
3.00e-09 |
|
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.
Pssm-ID: 119321 [Multi-domain] Cd Length: 263 Bit Score: 58.19 E-value: 3.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 54 TGMISLCQMSFAGVGAWVTGYLnLIEAPGGLAVWVLLGGLAAVPVGIAIGLPALRLRgINLAIVTLSFAAAFDTVLATIT 133
Cdd:cd06579 17 TGGIDLSVGSVAALSAVVAALL-LVNAGLPIPLAILAALAVGALIGLLNGLLVAYLR-IPPFIVTLGTMFILRGLALLIT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 134 FPGQTSFTQVARPDLFASDRGYFLFVLLAYGIIAVVLEFI--SHSRLGASWLAVRHSERAAAANGISIPRAKLSAFAISA 211
Cdd:cd06579 95 GGRPISGLPPLFSFFLGGGLILGIPVPVLIALAVALVAWFllRRTRFGRYLYAVGGNPEAARLSGINVRRVKILAYVLSG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 212 FISGISGGLLAGYLGTlVAENFSMMQSLALFAVATMAGAHFT------LGALIGGVLIVLFPELLRRLNLPQDIGNVFFA 285
Cdd:cd06579 175 LLAGLAGILLAARLGS-AQPTAGNGYELDAIAAVVLGGTSLTggrgsvLGTLLGALLLGVLNNGLNLLGVSSFWQQIVKG 253
|
.
gi 492864881 286 L 286
Cdd:cd06579 254 A 254
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
335-538 |
3.16e-09 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 57.44 E-value: 3.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRY-----GAVT--ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAG-FLPRyDGTVLLH--GKPLEALS 404
Cdd:COG4778 3 TLLEVENLSKTFtlhlqGGKRlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGnYLPD-SGSILVRhdGGWVDLAQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 405 ATARAKAGIRRTW-----QTTRIAPelRVGDyIRLAAGP---------IGQTELESLLGWFGCPPP--ETPIASVDAGTR 468
Cdd:COG4778 82 ASPREILALRRRTigyvsQFLRVIP--RVSA-LDVVAEPllergvdreEARARARELLARLNLPERlwDLPPATFSGGEQ 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 469 RLLDVAGAVASRAPVILLDEPAAgiSYDEA--LKLGERIAAIPATfGSAVLLIEHDMDLVRRACTaiTVFDF 538
Cdd:COG4778 159 QRVNIARGFIADPPLLLLDEPTA--SLDAAnrAVVVELIEEAKAR-GTAIIGIFHDEEVREAVAD--RVVDV 225
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
336-554 |
3.37e-09 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 58.60 E-value: 3.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYG----AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGfLPRYDGTVL-----LHGKPLEALSAT 406
Cdd:PRK11022 3 LLNVDKLSVHFGdesaPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMG-LIDYPGRVMaekleFNGQDLQRISEK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 407 ARAK---AGIRRTWQ--TTRIAPELRVG----DYIRLAAGPIGQTELE---SLLGWFGCPPPETPIA----SVDAGTRRL 470
Cdd:PRK11022 82 ERRNlvgAEVAMIFQdpMTSLNPCYTVGfqimEAIKVHQGGNKKTRRQraiDLLNQVGIPDPASRLDvyphQLSGGMSQR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 471 LDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEV 550
Cdd:PRK11022 162 VMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDI 241
|
....
gi 492864881 551 LDMP 554
Cdd:PRK11022 242 FRAP 245
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
326-565 |
3.47e-09 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 58.08 E-value: 3.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 326 NSAPAIgegtvlEVRDLTVRYGAVT--ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEAL 403
Cdd:PRK13632 3 NKSVMI------KVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 404 SAT-ARAKAGIrrTWQTtriaPE-----LRVGDYIrlAAGpigqteLESllgwfGCPPPE--TPI---ASVDAGTRRLLD 472
Cdd:PRK13632 77 NLKeIRKKIGI--IFQN----PDnqfigATVEDDI--AFG------LEN-----KKVPPKkmKDIiddLAKKVGMEDYLD 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 473 -----VAG------AVASrapVILLDePAAgISYDEAL---------KLGERIAAIPATFGSAVLLIEHDMDLVRRACTA 532
Cdd:PRK13632 138 kepqnLSGgqkqrvAIAS---VLALN-PEI-IIFDESTsmldpkgkrEIKKIMVDLRKTRKKTLISITHDMDEAILADKV 212
|
250 260 270
....*....|....*....|....*....|....
gi 492864881 533 ItVFDFGQVIASGEPAEVL-DMPEVQKAYMGVDF 565
Cdd:PRK13632 213 I-VFSEGKLIAQGKPKEILnNKEILEKAKIDSPF 245
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
327-549 |
3.56e-09 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 59.41 E-value: 3.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 327 SAPAIGEGTVLEVRDLTVRYGAVTalnkvnLTVPAGT-----VVGLVGPNGAGKSTLVDAIAGFL----PRYDGTVLLHG 397
Cdd:COG1245 332 PRREKEEETLVEYPDLTKSYGGFS------LEVEGGEiregeVLGIVGPNGIGKTTFAKILAGVLkpdeGEVDEDLKISY 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 398 KPlealsatarakagirrtwQTTRIAPELRVGDYIRLAAGP-----IGQTE------LESLLgwfgcpppETPIASVDAG 466
Cdd:COG1245 406 KP------------------QYISPDYDGTVEEFLRSANTDdfgssYYKTEiikplgLEKLL--------DKNVKDLSGG 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 467 TRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDfgqviasGE 546
Cdd:COG1245 460 ELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHDIYLIDYISDRLMVFE-------GE 532
|
...
gi 492864881 547 PAE 549
Cdd:COG1245 533 PGV 535
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
317-555 |
3.94e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 57.80 E-value: 3.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 317 ARSAAQALANSAPAIGegtvleVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLV-------DAIAGFlpRY 389
Cdd:PRK14271 8 GQSGAADVDAAAPAMA------AVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLrtlnrmnDKVSGY--RY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 390 DGTVLLHGKPLEALSATARAKAGIRRTWQTTRIAPeLRVGDYI-----------RLAAGPIGQTELESLLGWFGCPP--P 456
Cdd:PRK14271 80 SGDVLLGGRSIFNYRDVLEFRRRVGMLFQRPNPFP-MSIMDNVlagvrahklvpRKEFRGVAQARLTEVGLWDAVKDrlS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 457 ETPIaSVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFgsAVLLIEHDMDLVRRACTAITVF 536
Cdd:PRK14271 159 DSPF-RLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALF 235
|
250
....*....|....*....
gi 492864881 537 DFGQVIASGEPAEVLDMPE 555
Cdd:PRK14271 236 FDGRLVEEGPTEQLFSSPK 254
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
352-555 |
6.64e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 56.98 E-value: 6.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 352 LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRY------DGTVLLHGKPLEALSATA-RAKAGIrrTWQTTRIAP 424
Cdd:PRK14246 26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYdskikvDGKVLYFGKDIFQIDAIKlRKEVGM--VFQQPNPFP 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 425 ELRVGDYIRLAAGPIGQTE-------LESLLGWFGCPPP-----ETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAG 492
Cdd:PRK14246 104 HLSIYDNIAYPLKSHGIKEkreikkiVEECLRKVGLWKEvydrlNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSM 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 493 ISYDEALKLGERIAAIPATFgsAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPE 555
Cdd:PRK14246 184 IDIVNSQAIEKLITELKNEI--AIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPK 244
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
336-560 |
6.72e-09 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 57.14 E-value: 6.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP--------RYDGTVLLHGKPLEALSAT- 406
Cdd:PRK13547 1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTgggaprgaRVTGDVTLNGEPLAAIDAPr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 407 -ARAKAGIRrtwQTTRIAPELRVGDYIRLAAGPIGQTELESLLGWFGCPPPETPIASVDAGTRRllDV------------ 473
Cdd:PRK13547 81 lARLRAVLP---QAAQPAFAFSAREIVLLGRYPHARRAGALTHRDGEIAWQALALAGATALVGR--DVttlsggelarvq 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 474 ----------AGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIA 543
Cdd:PRK13547 156 farvlaqlwpPHDAAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVA 235
|
250
....*....|....*..
gi 492864881 544 SGEPAEVLDMPEVQKAY 560
Cdd:PRK13547 236 HGAPADVLTPAHIARCY 252
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
337-555 |
8.21e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 56.77 E-value: 8.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFL-----PRYDGTVLLHGKPLEALSATA---R 408
Cdd:PRK14267 5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLelneeARVEGEVRLFGRNIYSPDVDPievR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 409 AKAGIrrTWQTTRIAPELRVGDYI----RLAAGPIGQTELESLLGWFGCPPP----------ETPiASVDAGTRRLLDVA 474
Cdd:PRK14267 85 REVGM--VFQYPNPFPHLTIYDNVaigvKLNGLVKSKKELDERVEWALKKAAlwdevkdrlnDYP-SNLSGGQRQRLVIA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 475 GAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFgsAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:PRK14267 162 RALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEY--TIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENP 239
|
.
gi 492864881 555 E 555
Cdd:PRK14267 240 E 240
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
337-398 |
8.22e-09 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 55.94 E-value: 8.22e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 337 LEVRDLTVRYG-----AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGK 398
Cdd:cd03250 1 ISVEDASFTWDsgeqeTSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS 67
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
337-554 |
8.91e-09 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 57.22 E-value: 8.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRY----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP----------RYDGTVLLhgkpleA 402
Cdd:COG4170 4 LDIRNLTIEIdtpqGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKdnwhvtadrfRWNGIDLL------K 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 403 LSATARAKAgIRR----TWQ--TTRIAPELRVGDYIRLAagpIGQTELEsllGWF------------------GCPPPET 458
Cdd:COG4170 78 LSPRERRKI-IGReiamIFQepSSCLDPSAKIGDQLIEA---IPSWTFK---GKWwqrfkwrkkraiellhrvGIKDHKD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 459 PIAS----VDAGTRRLLDVAGAVASRAPVILLDEPAAGI-SYDEA--LKLgerIAAIPATFGSAVLLIEHDMDLVRRACT 531
Cdd:COG4170 151 IMNSypheLTEGECQKVMIAMAIANQPRLLIADEPTNAMeSTTQAqiFRL---LARLNQLQGTSILLISHDLESISQWAD 227
|
250 260
....*....|....*....|...
gi 492864881 532 AITVFDFGQVIASGEPAEVLDMP 554
Cdd:COG4170 228 TITVLYCGQTVESGPTEQILKSP 250
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
352-561 |
1.29e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 56.38 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 352 LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAgIRRTWQTTRIAPELRVGDY 431
Cdd:PRK13641 23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKNLKK-LRKKVSLVFQFPEAQLFEN 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 432 IRLAA---GP--IGQTELES---LLGWFGCPPPETPIAS-----VDAGTRRLLDVAGAVASRAPVILLDEPAAGI---SY 495
Cdd:PRK13641 102 TVLKDvefGPknFGFSEDEAkekALKWLKKVGLSEDLISkspfeLSGGQMRRVAIAGVMAYEPEILCLDEPAAGLdpeGR 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 496 DEALKLGERIAAIpatfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPE-VQKAYM 561
Cdd:PRK13641 182 KEMMQLFKDYQKA----GHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKEwLKKHYL 244
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
310-555 |
1.42e-08 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 57.56 E-value: 1.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 310 FPRR------NRQARSAAQALANSAPAiGEgTVLEVRDLTVRYG-----------AVTALNKVNLTVPAGTVVGLVGPNG 372
Cdd:PRK10261 283 YPRRfplislEHPAKQEPPIEQDTVVD-GE-PILQVRNLVTRFPlrsgllnrvtrEVHAVEKVSFDLWPGETLSLVGESG 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 373 AGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSAtaRAKAGIRRTWQ------TTRIAPELRVGDYI-------RLAAGPI 439
Cdd:PRK10261 361 SGKSTTGRALLRLVESQGGEIIFNGQRIDTLSP--GKLQALRRDIQfifqdpYASLDPRQTVGDSImeplrvhGLLPGKA 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 440 GQTELESLLGWFGCPPPET---PiASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAV 516
Cdd:PRK10261 439 AAARVAWLLERVGLLPEHAwryP-HEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAY 517
|
250 260 270
....*....|....*....|....*....|....*....
gi 492864881 517 LLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPE 555
Cdd:PRK10261 518 LFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQ 556
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
328-402 |
1.64e-08 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 55.17 E-value: 1.64e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 328 APAIGEGTVlEVRDLTVRY---GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEA 402
Cdd:cd03248 4 APDHLKGIV-KFQNVTFAYptrPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQ 80
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
352-521 |
1.88e-08 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 54.97 E-value: 1.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 352 LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYD---GTVLLHGKPLEalsatarakagiRRTW--------QTT 420
Cdd:cd03234 23 LNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGQPRK------------PDQFqkcvayvrQDD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 421 RIAPELRVGDYIRLAA-------------GPIGQTELESLLGwfgcpppETPIA-----SVDAGTRRLLDVAGAVASRAP 482
Cdd:cd03234 91 ILLPGLTVRETLTYTAilrlprkssdairKKRVEDVLLRDLA-------LTRIGgnlvkGISGGERRRVSIAVQLLWDPK 163
|
170 180 190
....*....|....*....|....*....|....*....
gi 492864881 483 VILLDEPAAGISYDEALKLGERIAAIpATFGSAVLLIEH 521
Cdd:cd03234 164 VLILDEPTSGLDSFTALNLVSTLSQL-ARRNRIVILTIH 201
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
356-552 |
1.93e-08 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 55.36 E-value: 1.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 356 NLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPleaLSATARAKAGIRRTWQTTRIAPELRVGDYIRLA 435
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQD---HTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 436 AGP---------------IGQTELESLLgwfgcppPETPiASVDAGTRRLLDVAGAVASRAPVILLDEPAAGIsyDEALK 500
Cdd:PRK10771 96 LNPglklnaaqreklhaiARQMGIEDLL-------ARLP-GQLSGGQRQRVALARCLVREQPILLLDEPFSAL--DPALR 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 501 --LGERIAAIPATFGSAVLLIEHDM-DLVRRACTAITVFDfGQVIASGEPAEVLD 552
Cdd:PRK10771 166 qeMLTLVSQVCQERQLTLLMVSHSLeDAARIAPRSLVVAD-GRIAWDGPTDELLS 219
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
328-402 |
2.09e-08 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 57.06 E-value: 2.09e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 328 APAIGEGTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEA 402
Cdd:NF033858 258 PADDDDEPAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDA 332
|
|
| TM_PBP1_transp_TpRbsC_like |
cd06580 |
Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. ... |
48-286 |
2.64e-08 |
|
Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters, which are mainly involved in the uptake of branched-chain amino acids (AAs) or in the uptake of monosaccharides including ribose, galactose, and arabinose, and which generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction.
Pssm-ID: 119322 [Multi-domain] Cd Length: 234 Bit Score: 54.75 E-value: 2.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 48 GLVAGRTGMISL---CQMSFAGVGAWVTGYLNLIEAPGGLAVWVLLGGLAAVPVGIAIGLPALRLrGINLAIVTLSFaaa 124
Cdd:cd06580 11 VAISFRAGVFNIgleGQMLLGAFAAALVALYLGLPATGSLPLGLLAAALAGALWALLPALLKAKL-GVNEVISGLML--- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 125 fdtvlatitfpgqtsftqvarpDLFASDRGYFLFvLLAYGIIAVVLEFISHSRLGASWLAVRHSERAAAANGISIPRAKL 204
Cdd:cd06580 87 ----------------------NYIALGLTSYLL-LLALLLVILVWLLLYRTRFGLRLRAVGENPRAARYAGINVKRVRL 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 205 SAFAISAFISGISGGLLAGYLGTLVAENFSMMQSLALFAVATMAGAHFT---LGALIGGVLIVLFPELLRRLNLPQDIGN 281
Cdd:cd06580 144 LAMLISGALAGLAGAYLVLGVQGRFTEGMSAGYGFIAIAVALLGRWNPLgilLAALLFGALEAGGIALQRSGGVPSELVQ 223
|
....*
gi 492864881 282 VFFAL 286
Cdd:cd06580 224 VLPGI 228
|
|
| AraH |
COG1172 |
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ... |
26-286 |
3.09e-08 |
|
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];
Pssm-ID: 440785 Cd Length: 322 Bit Score: 55.50 E-value: 3.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 26 FPKYWVFLITAVFIVGIA-----------LQSLGLVAGRTGMISLCQM-------------SFAGVGAWVTGYLnLIEAP 81
Cdd:COG1172 16 LPELGLLLALVLLLVVFSilspgflspgnLSNILRQAAILGILALGMTlviitggidlsvgSVVALSGVVAALL-LVALG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 82 GGLAVWVLLGGLAAVPVGIAIGLPALRLRgINLAIVTLSFAAAFDTVLATITfpgqTSFTQVARPDLFAS-DRGYFLFV- 159
Cdd:COG1172 95 LPILLAILLALLVGALLGLLNGLLVAKLR-IPPFIVTLGTMFIARGLALLLT----GGRPISGLPDAFRAlGQGSLLGIp 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 160 --LLAYGIIAVVLEFI-SHSRLGASWLAVRHSERAAAANGISIPRAKLSAFAISAFISGISGGLLAGYLGTLVAenfSMM 236
Cdd:COG1172 170 vpVLIALVVALVAWFLlRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQP---NAG 246
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 237 QSLALFAVA-------TMAGAHFT-LGALIGGVLIVLFPELLRRLNLPQDIGNVFFAL 286
Cdd:COG1172 247 SGYELDAIAavviggtSLTGGRGSvLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGA 304
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
335-568 |
3.85e-08 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 54.80 E-value: 3.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDL--TVRYGA-------VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSA 405
Cdd:PRK15112 3 TLLEVRNLskTFRYRTgwfrrqtVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 406 TARAKAgIRRTWQ--TTRIAPELRVGDYIRLaagPIG-QTELES---------LLGWFGCPPPETP-----IASvdaGTR 468
Cdd:PRK15112 83 SYRSQR-IRMIFQdpSTSLNPRQRISQILDF---PLRlNTDLEPeqrekqiieTLRQVGLLPDHASyyphmLAP---GQK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 469 RLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPA 548
Cdd:PRK15112 156 QRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTA 235
|
250 260
....*....|....*....|..
gi 492864881 549 EVLDMP--EVQKAYMGVDFEEA 568
Cdd:PRK15112 236 DVLASPlhELTKRLIAGHFGEA 257
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
315-541 |
4.96e-08 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 55.56 E-value: 4.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 315 RQARSAAQALANSAPAIGEGTVLEVRDLTVR-YGAVtalNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTV 393
Cdd:PRK09700 244 RELQNRFNAMKENVSNLAHETVFEVRNVTSRdRKKV---RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEI 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 394 LLHGKPLEALSATARAKAGI------RR---------TWQTTRIAPELRVGDYirlaAGPIG-------------QTELE 445
Cdd:PRK09700 321 RLNGKDISPRSPLDAVKKGMayitesRRdngffpnfsIAQNMAISRSLKDGGY----KGAMGlfhevdeqrtaenQRELL 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 446 SLlgwfGCPPPETPIASVDAGTRRLLDVAGAVASRAPVILLDEPAAGI---SYDEALKLGERIaaipATFGSAVLLIEHD 522
Cdd:PRK09700 397 AL----KCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIdvgAKAEIYKVMRQL----ADDGKVILMVSSE 468
|
250
....*....|....*....
gi 492864881 523 MDLVRRACTAITVFDFGQV 541
Cdd:PRK09700 469 LPEIITVCDRIAVFCEGRL 487
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
336-418 |
7.44e-08 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 53.64 E-value: 7.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGfLPRY---DGTVLLHGKPLEALSATARAKAG 412
Cdd:PRK09580 1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAG-REDYevtGGTVEFKGKDLLELSPEDRAGEG 79
|
....*.
gi 492864881 413 IRRTWQ 418
Cdd:PRK09580 80 IFMAFQ 85
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
342-524 |
8.02e-08 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 55.18 E-value: 8.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 342 LTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGK-------------PLEALSATAR 408
Cdd:PRK10636 7 LQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNwqlawvnqetpalPQPALEYVID 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 409 AKAGIRRTWQTTRIAPELRVGDYIRLAAGPIG-------QTELESLLGWFGCPPP--ETPIASVDAGTRRLLDVAGAVAS 479
Cdd:PRK10636 87 GDREYRQLEAQLHDANERNDGHAIATIHGKLDaidawtiRSRAASLLHGLGFSNEqlERPVSDFSGGWRMRLNLAQALIC 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 492864881 480 RAPVILLDEPAAGISYDEALKLGERIAAIPATfgsaVLLIEHDMD 524
Cdd:PRK10636 167 RSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGT----LILISHDRD 207
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
336-534 |
8.61e-08 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 53.18 E-value: 8.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKA---- 411
Cdd:PRK10247 7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQvsyc 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 -------------GIRRTWQTTRIAPELRvgdyiRLAAGpigqteleslLGWFGCPPP--ETPIASVDAGTRRLLDVAGA 476
Cdd:PRK10247 87 aqtptlfgdtvydNLIFPWQIRNQQPDPA-----IFLDD----------LERFALPDTilTKNIAELSGGEKQRISLIRN 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 477 VASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAIT 534
Cdd:PRK10247 152 LQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEINHADKVIT 209
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
335-408 |
9.33e-08 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 54.18 E-value: 9.33e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATAR 408
Cdd:PRK09452 13 PLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENR 86
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
315-384 |
1.01e-07 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 54.74 E-value: 1.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 315 RQARSAA-----QALANSA---------------PAIGeGTVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAG 374
Cdd:PRK11819 284 RQAKSKArlaryEELLSEEyqkrnetneifippgPRLG-DKVIEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAG 362
|
90
....*....|
gi 492864881 375 KSTLVDAIAG 384
Cdd:PRK11819 363 KSTLFKMITG 372
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
339-386 |
1.02e-07 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 53.94 E-value: 1.02e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 492864881 339 VRDLTVR-YGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFL 386
Cdd:COG4586 24 LKGLFRReYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGIL 72
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
351-550 |
1.19e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 53.59 E-value: 1.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 351 ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAgIRRTWQTTRIAPELRVGD 430
Cdd:PRK13649 22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQ-IRKKVGLVFQFPESQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 431 YIRL---AAGP----IGQTELE-------SLLG----WFGCPPPEtpiasVDAGTRRLLDVAGAVASRAPVILLDEPAAG 492
Cdd:PRK13649 101 ETVLkdvAFGPqnfgVSQEEAEalareklALVGisesLFEKNPFE-----LSGGQMRRVAIAGILAMEPKILVLDEPTAG 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492864881 493 IS---YDEALKLGERIAAIpatfGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEV 550
Cdd:PRK13649 176 LDpkgRKELMTLFKKLHQS----GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDI 232
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
337-554 |
1.34e-07 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 53.96 E-value: 1.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARakaGIRRT 416
Cdd:PRK11432 7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQR---DICMV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 WQTTRIAPELRVGDYI-------RLAAGPIGQTELESL----LGWFGcpppETPIASVDAGTRRLLDVAGAVASRAPVIL 485
Cdd:PRK11432 84 FQSYALFPHMSLGENVgyglkmlGVPKEERKQRVKEALelvdLAGFE----DRYVDQISGGQQQRVALARALILKPKVLL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 486 LDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMP 554
Cdd:PRK11432 160 FDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQP 228
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
336-403 |
1.44e-07 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 52.11 E-value: 1.44e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEAL 403
Cdd:PRK13538 1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQ 68
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
335-550 |
1.48e-07 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 52.85 E-value: 1.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATA--RAKAG 412
Cdd:PRK11831 6 NLVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRlyTVRKR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 413 IRRTWQTTRIAPELRVGD--------YIRLAAGPIGQT---ELES--LLGWFGCPPPEtpiasVDAGTRRLLDVAGAVAS 479
Cdd:PRK11831 86 MSMLFQSGALFTDMNVFDnvayplreHTQLPAPLLHSTvmmKLEAvgLRGAAKLMPSE-----LSGGMARRAALARAIAL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 480 RAPVILLDEPAAG---ISYDEALKLgerIAAIPATFGSAVLLIEHDM-DLVRRACTAITVFDfGQVIASGEPAEV 550
Cdd:PRK11831 161 EPDLIMFDEPFVGqdpITMGVLVKL---ISELNSALGVTCVVVSHDVpEVLSIADHAYIVAD-KKIVAHGSAQAL 231
|
|
| TM_PBP1_branched-chain-AA_like |
cd06574 |
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette ... |
55-276 |
1.54e-07 |
|
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of monosaccharides including ribose, galactose, and arabinose. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. This group includes Escherichia coli LivM and LivH, two TMs which heterodimerize to form the translocation pathway of the E. coli branched-chain AA LIV-1/LS transporter. This transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) and LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine. Included in this group are proteins from transport systems that contain a single TM which homodimerizes to generate the transmembrane pore; for example E. coli RbsC, AlsC, and MglC, the TMs of the high affinity ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also to be involved in low affinity ribose transport.
Pssm-ID: 119320 [Multi-domain] Cd Length: 266 Bit Score: 53.05 E-value: 1.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 55 GMISLCQMSFAGVGAWVTGYLNLIEAPGGLAVwvLLGGLAAVPVGIAIGLPALRLRGINLAIVTLSFAAAF---DTVLAT 131
Cdd:cd06574 19 GFPDLTVDGSFPLGAAVAAILIVAGYNPWLAL--IAAILAGAAAGLVTGFLHTRLKINGLLAGILIMIGLYsinLRIMGG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 132 ITFPGQTSFTQVARPDLFASDRGYFLFVLLAYGIIAVVLEFIS--HSRLGASWLAVRHSERAAAANGISIPRAKLSAFAI 209
Cdd:cd06574 97 PNIPLGTRDTLLGLLLLFGISGTLSIPVVLLLIVLLVLFLVIWflRTKLGLAMRATGDNPDMARSLGINVDRTRILGLVI 176
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 210 SAFISGISGGLLAGYLGTLvaeNFSMMQSLALFAVA----------TMAGAHFTLGALIGGVLIVLFPELLRRLNLP 276
Cdd:cd06574 177 SNALAALGGALYAQYQGFA---DVNMGIGTGVIGLAaviiggaivgRRTIKASILGVIIGAILYRIALALALGSGLI 250
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
285-395 |
1.74e-07 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 54.04 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 285 ALGAVQ-ALS----SGETIAEtWT----RLAEklFprrnRQARSAAQALANSAPAIG--EGTVLEVRDLTVRYGAVTALN 353
Cdd:COG4178 307 AFGQVQgALSwfvdNYQSLAE-WRatvdRLAG--F----EEALEAADALPEAASRIEtsEDGALALEDLTLRTPDGRPLL 379
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 492864881 354 K-VNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLL 395
Cdd:COG4178 380 EdLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR 422
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
337-555 |
1.79e-07 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 52.66 E-value: 1.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIaGFLPR-YDGTVLLHGKPLEALSAT-ARAKAGIR 414
Cdd:PRK10619 6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCI-NFLEKpSEGSIVVNGQTINLVRDKdGQLKVADK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 RTWQTTRIAPELRVGDYIRLAAGPIGQTELES---LLGWFGCPPPETPIASVD-----------------AGTRRLLDVA 474
Cdd:PRK10619 85 NQLRLLRTRLTMVFQHFNLWSHMTVLENVMEApiqVLGLSKQEARERAVKYLAkvgideraqgkypvhlsGGQQQRVSIA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 475 GAVASRAPVILLDEPAAGIsyDEALkLGE--RIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD 552
Cdd:PRK10619 165 RALAMEPEVLLFDEPTSAL--DPEL-VGEvlRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFG 241
|
...
gi 492864881 553 MPE 555
Cdd:PRK10619 242 NPQ 244
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
337-408 |
1.92e-07 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 53.16 E-value: 1.92e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATAR 408
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDR 74
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
335-555 |
2.05e-07 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 52.44 E-value: 2.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGIR 414
Cdd:PRK11264 2 SAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTARSLSQQKGLIR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 415 R-------TWQTTRIAPELRVGDYIrlAAGPI---GQTELES------LLGWFGCPPPEtpiasvDAGTRRL-------L 471
Cdd:PRK11264 82 QlrqhvgfVFQNFNLFPHRTVLENI--IEGPVivkGEPKEEAtarareLLAKVGLAGKE------TSYPRRLsggqqqrV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 472 DVAGAVASRAPVILLDEPAAGIsyDEALkLGERIAAIP--ATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAE 549
Cdd:PRK11264 154 AIARALAMRPEVILFDEPTSAL--DPEL-VGEVLNTIRqlAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKA 230
|
....*.
gi 492864881 550 VLDMPE 555
Cdd:PRK11264 231 LFADPQ 236
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
331-493 |
2.14e-07 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 53.68 E-value: 2.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 331 IGEgTVLEVRDLT---VRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP-RYDGTVLLHGKPLEALSAT 406
Cdd:TIGR02633 253 IGD-VILEARNLTcwdVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPgKFEGNVFINGKPVDIRNPA 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 407 ARAKAGIRRTWQTTR---IAPELRVGDYIRLAA----GPIGQTELESLLGWFG---------CPPPETPIASVDAGTRRL 470
Cdd:TIGR02633 332 QAIRAGIAMVPEDRKrhgIVPILGVGKNITLSVlksfCFKMRIDAAAELQIIGsaiqrlkvkTASPFLPIGRLSGGNQQK 411
|
170 180
....*....|....*....|...
gi 492864881 471 LDVAGAVASRAPVILLDEPAAGI 493
Cdd:TIGR02633 412 AVLAKMLLTNPRVLILDEPTRGV 434
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
351-567 |
3.02e-07 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 53.36 E-value: 3.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 351 ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKP-LEALSATARAK-------------AGIRRT 416
Cdd:PRK13545 39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAaLIAISSGLNGQltgienielkglmMGLTKE 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 417 wQTTRIAPEL----RVGDYIrlaagpigqtelesllgwfgcpppETPIASVDAGTRRLLDVAGAVASRAPVILLdepaag 492
Cdd:PRK13545 119 -KIKEIIPEIiefaDIGKFI------------------------YQPVKTYSSGMKSRLGFAISVHINPDILVI------ 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 493 isyDEALKLGERiaaipaTF--------------GSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLD-MPEVQ 557
Cdd:PRK13545 168 ---DEALSVGDQ------TFtkkcldkmnefkeqGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDhYDEFL 238
|
250
....*....|
gi 492864881 558 KAYMGVDFEE 567
Cdd:PRK13545 239 KKYNQMSVEE 248
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
345-567 |
3.17e-07 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 52.73 E-value: 3.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 345 RYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALS-ATARA--KAGIRRTWQTTR 421
Cdd:PRK10070 37 KTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISdAELREvrRKKIAMVFQSFA 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 422 IAPELRVGDY----IRLAAGPIGQTELESL-------LGWFGCPPPEtpiaSVDAGTRRLLDVAGAVASRAPVILLDEPA 490
Cdd:PRK10070 117 LMPHMTVLDNtafgMELAGINAEERREKALdalrqvgLENYAHSYPD----ELSGGMRQRVGLARALAINPDILLMDEAF 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 491 AGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEVLDMPE---VQKAYMGVDFEE 567
Cdd:PRK10070 193 SALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPAndyVRTFFRGVDISQ 272
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
337-539 |
3.45e-07 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 50.40 E-value: 3.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRygavtALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAI---------AGFLPRYDGTVLLHGKPLEALSATa 407
Cdd:cd03238 1 LTVSGANVH-----NLQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGlyasgkarlISFLPKFSRNKLIFIDQLQFLIDV- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 408 rakaGIrrTWQT-TRIAPELRVGDYIRLAAGpigqTELESllgwfgcPPPETpiasvdagtrrlldvagavasrapVILL 486
Cdd:cd03238 75 ----GL--GYLTlGQKLSTLSGGELQRVKLA----SELFS-------EPPGT------------------------LFIL 113
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 492864881 487 DEPAAGISYDEALKLGERIAAIpATFGSAVLLIEHDMDLVrraCTAITVFDFG 539
Cdd:cd03238 114 DEPSTGLHQQDINQLLEVIKGL-IDLGNTVILIEHNLDVL---SSADWIIDFG 162
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
330-493 |
3.62e-07 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 53.01 E-value: 3.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 330 AIGEgTVLEVRDLTVRYGAVTA---LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP-RYDGTVLLHGKPLEALSA 405
Cdd:PRK13549 254 TIGE-VILEVRNLTAWDPVNPHikrVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKPVKIRNP 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 406 TARAKAGI------RRTWQttrIAPELRVGDYIRLAA-------GPI-GQTELESLLGWFG-----CPPPETPIASVDAG 466
Cdd:PRK13549 333 QQAIAQGIamvpedRKRDG---IVPVMGVGKNITLAAldrftggSRIdDAAELKTILESIQrlkvkTASPELAIARLSGG 409
|
170 180
....*....|....*....|....*..
gi 492864881 467 TRRLLDVAGAVASRAPVILLDEPAAGI 493
Cdd:PRK13549 410 NQQKAVLAKCLLLNPKILILDEPTRGI 436
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
337-397 |
4.67e-07 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 52.71 E-value: 4.67e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 337 LEVRDLTVRY-GAVT-ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHG 397
Cdd:PRK11176 342 IEFRNVTFTYpGKEVpALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDG 404
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
336-528 |
4.77e-07 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 50.97 E-value: 4.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRY--GAVTA--LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKA 411
Cdd:PRK11629 5 LLQCDNLCKRYqeGSVQTdvLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAEL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 GIRR---TWQTTRIAPELRVgdyIRLAAGP--IG-------QTELESLLGWFGCP------PPEtpiasVDAGTRRLLDV 473
Cdd:PRK11629 85 RNQKlgfIYQFHHLLPDFTA---LENVAMPllIGkkkpaeiNSRALEMLAAVGLEhranhrPSE-----LSGGERQRVAI 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 474 AGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRR 528
Cdd:PRK11629 157 ARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKR 211
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
336-554 |
5.02e-07 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 51.73 E-value: 5.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRY----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP----------RYDGTVLLHGKPLE 401
Cdd:PRK15093 3 LLDIRNLTIEFktsdGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKdnwrvtadrmRFDDIDLLRLSPRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 402 ALSATARAKAGIRRTWQTTrIAPELRVGDYIRLA------AGPIGQ------TELESLLGWFGCPPPETPIAS----VDA 465
Cdd:PRK15093 83 RRKLVGHNVSMIFQEPQSC-LDPSERVGRQLMQNipgwtyKGRWWQrfgwrkRRAIELLHRVGIKDHKDAMRSfpyeLTE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 466 GTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASG 545
Cdd:PRK15093 162 GECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETA 241
|
....*....
gi 492864881 546 EPAEVLDMP 554
Cdd:PRK15093 242 PSKELVTTP 250
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
331-556 |
7.52e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 51.39 E-value: 7.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 331 IGEGTVLEVRDLTVRYGA-----VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFL-PRYdGTVLL------HGK 398
Cdd:PRK13631 16 LSDDIILRVKNLYCVFDEkqeneLVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIkSKY-GTIQVgdiyigDKK 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 399 PLEALSATARAKA-----GIRRTWQTTRIAPELRV-GDYIR--LAAGPI--GQTELES------LLGWFGCPPP--ETPI 460
Cdd:PRK13631 95 NNHELITNPYSKKiknfkELRRRVSMVFQFPEYQLfKDTIEkdIMFGPValGVKKSEAkklakfYLNKMGLDDSylERSP 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 461 ASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITVFDFGQ 540
Cdd:PRK13631 175 FGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVIVMDKGK 253
|
250
....*....|....*.
gi 492864881 541 VIASGEPAEVLDMPEV 556
Cdd:PRK13631 254 ILKTGTPYEIFTDQHI 269
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
336-535 |
7.93e-07 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 52.32 E-value: 7.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVT--ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLealsataraKAGI 413
Cdd:TIGR01257 1937 ILRLNELTKVYSGTSspAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSI---------LTNI 2007
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 RRTWQTTRIAPELRVGD-----------YIRLAAGPigQTELESLLGW----FGCPPPETPIA-SVDAGTRRLLDVAGAV 477
Cdd:TIGR01257 2008 SDVHQNMGYCPQFDAIDdlltgrehlylYARLRGVP--AEEIEKVANWsiqsLGLSLYADRLAgTYSGGNKRKLSTAIAL 2085
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 492864881 478 ASRAPVILLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRRACTAITV 535
Cdd:TIGR01257 2086 IGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAI 2142
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
336-527 |
1.02e-06 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 51.71 E-value: 1.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLhgkplealsatarAKaGIRR 415
Cdd:PRK10636 312 LLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-------------AK-GIKL 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 416 TWQTTRIAPELRVGD-----YIRLAAGPIGQtELESLLGWFGCPPPET--PIASVDAGTRRLLDVAGAVASRAPVILLDE 488
Cdd:PRK10636 378 GYFAQHQLEFLRADEsplqhLARLAPQELEQ-KLRDYLGGFGFQGDKVteETRRFSGGEKARLVLALIVWQRPNLLLLDE 456
|
170 180 190
....*....|....*....|....*....|....*....
gi 492864881 489 PAAGISYDEALKLGEriAAIpaTFGSAVLLIEHDMDLVR 527
Cdd:PRK10636 457 PTNHLDLDMRQALTE--ALI--DFEGALVVVSHDRHLLR 491
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
329-551 |
1.12e-06 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 51.87 E-value: 1.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 329 PAIGEgtvLEVRDLTVRY--GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLealsat 406
Cdd:TIGR00957 1280 PPRGR---VEFRNYCLRYreDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNI------ 1350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 407 arAKAGIRRTWQTTRIAPELRV--GDYIRLAAGPIGQ---------TELESLLGWFGCPPPETPIA------SVDAGTRR 469
Cdd:TIGR00957 1351 --AKIGLHDLRFKITIIPQDPVlfSGSLRMNLDPFSQysdeevwwaLELAHLKTFVSALPDKLDHEcaeggeNLSVGQRQ 1428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 470 LLDVAGAVASRAPVILLDEPAAGISydeaLKLGERI-AAIPATFGS-AVLLIEHDMDLVRRAcTAITVFDFGQVIASGEP 547
Cdd:TIGR00957 1429 LVCLARALLRKTKILVLDEATAAVD----LETDNLIqSTIRTQFEDcTVLTIAHRLNTIMDY-TRVIVLDKGEVAEFGAP 1503
|
....
gi 492864881 548 AEVL 551
Cdd:TIGR00957 1504 SNLL 1507
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
338-400 |
1.27e-06 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 49.85 E-value: 1.27e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 338 EVRDLTVRYGA---VTALNKVNLTVPAGTVVGLVGPNGAGKSTlvdaIAGFLPR-YD---GTVLLHGKPL 400
Cdd:cd03249 2 EFKNVSFRYPSrpdVPILKGLSLTIPPGKTVALVGSSGCGKST----VVSLLERfYDptsGEILLDGVDI 67
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
335-382 |
1.29e-06 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 50.16 E-value: 1.29e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 492864881 335 TVLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAI 382
Cdd:PRK14239 4 PILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSI 51
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
337-551 |
1.40e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 50.47 E-value: 1.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRYGA-----VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKA 411
Cdd:PRK13651 3 IKVKNIVKIFNKklpteLKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 GIRR-TWQTTRI-----APELR--VGDYIRLAA--------------GPI--GQTELESL------LGWFGCPP---PET 458
Cdd:PRK13651 83 VLEKlVIQKTRFkkikkIKEIRrrVGVVFQFAEyqlfeqtiekdiifGPVsmGVSKEEAKkraakyIELVGLDEsylQRS 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 459 PIAsVDAGTRRLLDVAGAVASRAPVILLDEPAAGIS---YDEALKLGERIAAIpatfGSAVLLIEHDMDLVRRACTAITV 535
Cdd:PRK13651 163 PFE-LSGGQKRRVALAGILAMEPDFLVFDEPTAGLDpqgVKEILEIFDNLNKQ----GKTIILVTHDLDNVLEWTKRTIF 237
|
250
....*....|....*.
gi 492864881 536 FDFGQVIASGEPAEVL 551
Cdd:PRK13651 238 FKDGKIIKDGDTYDIL 253
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
351-567 |
1.41e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 50.16 E-value: 1.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 351 ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGkpleaLSATARAKAG-IRRTWQTTRIA---PEL 426
Cdd:PRK13646 22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDD-----ITITHKTKDKyIRPVRKRIGMVfqfPES 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 427 RV-GDYIR--LAAGPIG-QTELES-------LLGWFGCPP---PETPIaSVDAGTRRLLDVAGAVASRAPVILLDEPAAG 492
Cdd:PRK13646 97 QLfEDTVEreIIFGPKNfKMNLDEvknyahrLLMDLGFSRdvmSQSPF-QMSGGQMRKIAIVSILAMNPDIIVLDEPTAG 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 493 ISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVIASGEPAEV-----------LDMPEVQKayM 561
Cdd:PRK13646 176 LDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELfkdkkkladwhIGLPEIVQ--L 253
|
....*.
gi 492864881 562 GVDFEE 567
Cdd:PRK13646 254 QYDFEQ 259
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
336-432 |
1.81e-06 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 50.09 E-value: 1.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYG-------------AVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEA 402
Cdd:PRK15079 8 LLEVADLKVHFDikdgkqwfwqppkTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLG 87
|
90 100 110
....*....|....*....|....*....|....
gi 492864881 403 LSATAR--AKAGIRRTWQT--TRIAPELRVGDYI 432
Cdd:PRK15079 88 MKDDEWraVRSDIQMIFQDplASLNPRMTIGEII 121
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
351-397 |
2.46e-06 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 49.43 E-value: 2.46e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 492864881 351 ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHG 397
Cdd:PRK13546 39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG 85
|
|
| NupP |
COG4603 |
ABC-type guanosine uptake system NupNOPQ, permease component NupP [Nucleotide transport and ... |
61-286 |
2.74e-06 |
|
ABC-type guanosine uptake system NupNOPQ, permease component NupP [Nucleotide transport and metabolism];
Pssm-ID: 443653 [Multi-domain] Cd Length: 356 Bit Score: 49.73 E-value: 2.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 61 QMSFAGVGA-WVTGYLNLIEAPGGLAVWVLLGGLAAvpvGIAIGLPA-LRLR-GINLAIVT--LSFAAAF------DTVL 129
Cdd:COG4603 92 QLYLGALAAaAVGLALPGLPGPLHLPLALLAGALAG---ALWAAIPGlLKARfGVNEVITTlmLNYIALYlvnylvRGPL 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 130 A--TITFPGQTSFTQVAR-PDLFASDRGYFLFVLlayGIIAVVLE--FISHSRLGASWLAVRHSERAAAANGISIPRAKL 204
Cdd:COG4603 169 RdpGSGFPQTPPIPESARlPRLLPGTRLHLGLLI---ALLAAVLVwvLLNRTTLGYELRAVGLNPRAARYAGINVKRLIV 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 205 SAFAISAFISGISGGL-LAGYLGTLVAeNFSMMQSLALFAVATMAGAHFtLGALIGGVLIVLF----PELLRRLNLPQDI 279
Cdd:COG4603 246 LAMLISGALAGLAGAVeVLGVQGRLTP-GFSPGYGFTGIAVALLGRNNP-LGIILAALLFGALyvggDAMQRALGVPSEI 323
|
....*..
gi 492864881 280 GNVFFAL 286
Cdd:COG4603 324 VDVIQGL 330
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
306-401 |
3.58e-06 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 50.11 E-value: 3.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 306 AEKLFPRRNRQARSaaQALANSAPAIGEGTVlEVRDLTVRYGA---VTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAI 382
Cdd:TIGR00958 451 SEKVFEYLDRKPNI--PLTGTLAPLNLEGLI-EFQDVSFSYPNrpdVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALL 527
|
90
....*....|....*....
gi 492864881 383 AGFLPRYDGTVLLHGKPLE 401
Cdd:TIGR00958 528 QNLYQPTGGQVLLDGVPLV 546
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
336-550 |
4.44e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 48.57 E-value: 4.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRYGAVT---ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLealsaTARAKAG 412
Cdd:PRK13650 4 IIEVKNLTFKYKEDQekyTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLL-----TEENVWD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 413 IRRTWQTTRIAPELR-VGDYIR------LAAGPIGQTELES-------LLGW--FGCPPPetpiASVDAGTRRLLDVAGA 476
Cdd:PRK13650 79 IRHKIGMVFQNPDNQfVGATVEddvafgLENKGIPHEEMKErvnealeLVGMqdFKEREP----ARLSGGQKQRVAIAGA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492864881 477 VASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAItVFDFGQVIASGEPAEV 550
Cdd:PRK13650 155 VAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVALSDRVL-VMKNGQVESTSTPREL 227
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
337-393 |
5.42e-06 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 49.12 E-value: 5.42e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTV 393
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV 376
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
238-552 |
5.56e-06 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 49.56 E-value: 5.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 238 SLALFAVATMAGAHFTLGALIGGVLIVLFPELLRRLN-LPQDIGNVffalgaVQALSSGETIAETWTRlaEKLFPrrnrq 316
Cdd:TIGR00957 555 ALITFAVYVTVDENNILDAEKAFVSLALFNILRFPLNiLPMVISSI------VQASVSLKRLRIFLSH--EELEP----- 621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 317 arsaaQALANSAPAIGEGTVLEVRDLTVRY--GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVL 394
Cdd:TIGR00957 622 -----DSIERRTIKPGEGNSITVHNATFTWarDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVH 696
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 395 LHGK----PLEALSATARAKAGI-----------RRTWQTTRIAPELRVgdyirLAAGpiGQTEleslLGWFGcpppetp 459
Cdd:TIGR00957 697 MKGSvayvPQQAWIQNDSLRENIlfgkalnekyyQQVLEACALLPDLEI-----LPSG--DRTE----IGEKG------- 758
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 460 iASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATF-GSAVLLIEHDMDLVRRAcTAITVFDF 538
Cdd:TIGR00957 759 -VNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFEHVIGPEGVLkNKTRILVTHGISYLPQV-DVIIVMSG 836
|
330
....*....|....
gi 492864881 539 GQVIASGEPAEVLD 552
Cdd:TIGR00957 837 GKISEMGSYQELLQ 850
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
329-413 |
6.88e-06 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 48.63 E-value: 6.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 329 PAIGEgTVLEVRDLTVRYGAVT---ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAG--FLPRYDGTVLLHGKPLEaL 403
Cdd:NF040905 251 PKIGE-VVFEVKNWTVYHPLHPerkVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGrsYGRNISGTVFKDGKEVD-V 328
|
90
....*....|.
gi 492864881 404 SATARA-KAGI 413
Cdd:NF040905 329 STVSDAiDAGL 339
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
337-402 |
8.04e-06 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 48.81 E-value: 8.04e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 337 LEVRDLTVRYGAVT-ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEA 402
Cdd:PRK10522 323 LELRNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTA 389
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
337-379 |
8.23e-06 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 47.32 E-value: 8.23e-06
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLV 379
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLL 45
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
336-558 |
9.01e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 47.49 E-value: 9.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 336 VLEVRDLTVRY--GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFL-----PRYDGTVLlhGKPLEALSA-TA 407
Cdd:PRK13640 5 IVEFKHVSFTYpdSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlpddnPNSKITVD--GITLTAKTVwDI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 408 RAKAGIrrTWQT-------------------TRIAPELRVGDYIRLAAGPIGQTELEsllgwfgcpppETPIASVDAGTR 468
Cdd:PRK13640 83 REKVGI--VFQNpdnqfvgatvgddvafgleNRAVPRPEMIKIVRDVLADVGMLDYI-----------DSEPANLSGGQK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 469 RLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRAcTAITVFDFGQVIASGEPA 548
Cdd:PRK13640 150 QRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEANMA-DQVLVLDDGKLLAQGSPV 228
|
250 260
....*....|....*....|.
gi 492864881 549 EV-----------LDMPEVQK 558
Cdd:PRK13640 229 EIfskvemlkeigLDIPFVYK 249
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
322-560 |
9.28e-06 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 48.55 E-value: 9.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 322 QALANSAP-------AIGEGTVLEVRDLTVRY-----------GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIA 383
Cdd:PRK15134 254 QKLLNSEPsgdpvplPEPASPLLDVEQLQVAFpirkgilkrtvDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALL 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 384 GFLpRYDGTVLLHGKPLEALSatARAKAGIRRTWQT------TRIAPELRVGDYI---------RLAAGPIGQTELESL- 447
Cdd:PRK15134 334 RLI-NSQGEIWFDGQPLHNLN--RRQLLPVRHRIQVvfqdpnSSLNPRLNVLQIIeeglrvhqpTLSAAQREQQVIAVMe 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 448 -LGWfgcpPPET----PiASVDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHD 522
Cdd:PRK15134 411 eVGL----DPETrhryP-AEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHD 485
|
250 260 270
....*....|....*....|....*....|....*...
gi 492864881 523 MDLVRRACTAITVFDFGQVIASGEPAEVLDMPevQKAY 560
Cdd:PRK15134 486 LHVVRALCHQVIVLRQGEVVEQGDCERVFAAP--QQEY 521
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
319-398 |
1.22e-05 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 48.09 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 319 SAAQALANSAPAIgegtvlEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPR-YDGTVLLHG 397
Cdd:PRK10938 249 SARHALPANEPRI------VLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQgYSNDLTLFG 322
|
.
gi 492864881 398 K 398
Cdd:PRK10938 323 R 323
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
341-523 |
1.22e-05 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 46.98 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 341 DLTVRYGaVTALNKVNLTVPA-GTVVGLVGPNGAGKSTLVDAIAGFL----------PRYDG--------------TVLL 395
Cdd:cd03236 5 EPVHRYG-PNSFKLHRLPVPReGQVLGLVGPNGIGKSTALKILAGKLkpnlgkfddpPDWDEildefrgselqnyfTKLL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 396 HG------KP--LEALSATARAKAG--IRRTwqttriaPELRVGDYIrlaagpIGQTELESLLgwfgcpppETPIASVDA 465
Cdd:cd03236 84 EGdvkvivKPqyVDLIPKAVKGKVGelLKKK-------DERGKLDEL------VDQLELRHVL--------DRNIDQLSG 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 466 GTRRLLDVAGAVASRAPVILLDEPAagiSYdeaLKLGERIAAIP-----ATFGSAVLLIEHDM 523
Cdd:cd03236 143 GELQRVAIAAALARDADFYFFDEPS---SY---LDIKQRLNAARlirelAEDDNYVLVVEHDL 199
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
313-403 |
1.27e-05 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 48.17 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 313 RNRQARSAAQALANSAPAIGEGT--------VLEVRDLTVRYGAVT--ALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAI 382
Cdd:PRK10789 282 RGSAAYSRIRAMLAEAPVVKDGSepvpegrgELDVNIRQFTYPQTDhpALENVNFTLKPGQMLGICGPTGSGKSTLLSLI 361
|
90 100
....*....|....*....|.
gi 492864881 383 AGFLPRYDGTVLLHGKPLEAL 403
Cdd:PRK10789 362 QRHFDVSEGDIRFHDIPLTKL 382
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
337-400 |
1.43e-05 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 46.45 E-value: 1.43e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 337 LEVRDLTVRYGA-VTALNKVNLTVPAGTVVGLVGPNGAGKSTlvdaIAGFLPR-YD---GTVLLHGKPL 400
Cdd:cd03253 1 IEFENVTFAYDPgRPVLKDVSFTIPAGKKVAIVGPSGSGKST----ILRLLFRfYDvssGSILIDGQDI 65
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
340-555 |
1.71e-05 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 47.33 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 340 RDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSAtarAKAGIRRTWQT 419
Cdd:PRK11000 7 RNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPP---AERGVGMVFQS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 420 TRIAPELRVGDY----IRLA-------------AGPIGQteLESLLgwfgcpppETPIASVDAGTRRLLDVAGAVASRAP 482
Cdd:PRK11000 84 YALYPHLSVAENmsfgLKLAgakkeeinqrvnqVAEVLQ--LAHLL--------DRKPKALSGGQRQRVAIGRTLVAEPS 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 483 VILLDEPAAGIsyDEALKLGER--IAAIPATFGSAVLLIEHD----MDLVRRactaITVFDFGQVIASGEPAEVLDMPE 555
Cdd:PRK11000 154 VFLLDEPLSNL--DAALRVQMRieISRLHKRLGRTMIYVTHDqveaMTLADK----IVVLDAGRVAQVGKPLELYHYPA 226
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
337-491 |
1.94e-05 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 46.77 E-value: 1.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRY--GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLpRYDGTVLLHG-----KPLEA------- 402
Cdd:cd03289 3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLL-NTEGDIQIDGvswnsVPLQKwrkafgv 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 403 -------LSATARAKAGIRRTWQTTRIapeLRVGDYIRLAAgPIGQ--TELESLLGWFGCpppetpiaSVDAGTRRLLDV 473
Cdd:cd03289 82 ipqkvfiFSGTFRKNLDPYGKWSDEEI---WKVAEEVGLKS-VIEQfpGQLDFVLVDGGC--------VLSHGHKQLMCL 149
|
170
....*....|....*...
gi 492864881 474 AGAVASRAPVILLDEPAA 491
Cdd:cd03289 150 ARSVLSKAKILLLDEPSA 167
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
337-491 |
2.43e-05 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 47.60 E-value: 2.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 337 LEVRDLTVRY--GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLpRYDGTVLLHGKPLEALSATARAKA--- 411
Cdd:TIGR01271 1218 MDVQGLTAKYteAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLL-STEGEIQIDGVSWNSVTLQTWRKAfgv 1296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 412 ---------GIRRtwqtTRIAPELRVGDY-IRLAAGPIGqteLESLLGWFgcpPPETPIASVDAGT------RRLLDVAG 475
Cdd:TIGR01271 1297 ipqkvfifsGTFR----KNLDPYEQWSDEeIWKVAEEVG---LKSVIEQF---PDKLDFVLVDGGYvlsnghKQLMCLAR 1366
|
170
....*....|....*.
gi 492864881 476 AVASRAPVILLDEPAA 491
Cdd:TIGR01271 1367 SILSKAKILLLDEPSA 1382
|
|
| BCA_ABC_TP_C |
pfam12399 |
Branched-chain amino acid ATP-binding cassette transporter; This domain family is found in ... |
540-564 |
3.94e-05 |
|
Branched-chain amino acid ATP-binding cassette transporter; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 30 amino acids in length. The family is found in association with pfam00005. There is a conserved AYLG sequence motif. This family is the C terminal of an ATP dependent branched-chain amino acid transporter. This domain is essential for LPS transport, through critical interactions with Walker A and switch helix domains.
Pssm-ID: 463560 Cd Length: 25 Bit Score: 40.70 E-value: 3.94e-05
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
325-501 |
6.03e-05 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 46.03 E-value: 6.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 325 ANSAPAIGEGTvlEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP--RYDGTVLLHGKPLea 402
Cdd:PLN03211 59 SNIKRILGHKP--KISDETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQgnNFTGTILANNRKP-- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 403 lsatarAKAGIRRTWQTTR---IAPELRVGD------YIRLAAGPIGQTEL---ESLLGWFGCPPPE------TPIASVD 464
Cdd:PLN03211 135 ------TKQILKRTGFVTQddiLYPHLTVREtlvfcsLLRLPKSLTKQEKIlvaESVISELGLTKCEntiignSFIRGIS 208
|
170 180 190
....*....|....*....|....*....|....*..
gi 492864881 465 AGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKL 501
Cdd:PLN03211 209 GGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRL 245
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
337-396 |
6.86e-05 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 45.56 E-value: 6.86e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492864881 337 LEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGF--LPRYDGTVLLH 396
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIIYH 62
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
352-549 |
8.67e-05 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 44.32 E-value: 8.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 352 LNKVNLTVPAGT-----VVGLVGPNGAGKSTLVDAIAGFL----------------------PRYDGTV--LLHGKplea 402
Cdd:cd03237 10 LGEFTLEVEGGSiseseVIGILGPNGIGKTTFIKMLAGVLkpdegdieieldtvsykpqyikADYEGTVrdLLSSI---- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 403 lsataRAKAGIRRTWQTTRIAPelrvgdyirlaagpigqTELESLLgwfgcpppETPIASVDAGTRRLLDVAGAVASRAP 482
Cdd:cd03237 86 -----TKDFYTHPYFKTEIAKP-----------------LQIEQIL--------DREVPELSGGELQRVAIAACLSKDAD 135
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492864881 483 VILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDfgqviasGEPAE 549
Cdd:cd03237 136 IYLLDEPSAYLDVEQRLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIVFE-------GEPSV 195
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
337-399 |
9.73e-05 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 42.91 E-value: 9.73e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492864881 337 LEVRDLTVRYGAVTAL-NKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKP 399
Cdd:cd03223 1 IELENLSLATPDGRVLlKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEGE 64
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
352-413 |
1.05e-04 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 45.20 E-value: 1.05e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492864881 352 LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFlprYD---GTVLLHGKPLEALSATA-RAKAGI 413
Cdd:COG5265 374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRF---YDvtsGRILIDGQDIRDVTQASlRAAIGI 436
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
334-493 |
1.08e-04 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 44.99 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 334 GTVLEVRDLTvryGAvtALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGI 413
Cdd:PRK10762 255 EVRLKVDNLS---GP--GVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGI 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 -------------------------------RRTWQTTRIAPELRVGDYIRLaagpigqtelesllgwFG--CPPPETPI 460
Cdd:PRK10762 330 vyisedrkrdglvlgmsvkenmsltalryfsRAGGSLKHADEQQAVSDFIRL----------------FNikTPSMEQAI 393
|
170 180 190
....*....|....*....|....*....|...
gi 492864881 461 ASVDAGTRRLLDVAGAVASRAPVILLDEPAAGI 493
Cdd:PRK10762 394 GLLSGGNQQKVAIARGLMTRPKVLILDEPTRGV 426
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
362-402 |
1.16e-04 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 45.04 E-value: 1.16e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 492864881 362 GTVVGLVGPNGAGKSTLVDAIAGFLPR---YDGTVLLHGKPLEA 402
Cdd:TIGR00955 51 GELLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGMPIDA 94
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
335-548 |
1.33e-04 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 44.66 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRygavtALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGI- 413
Cdd:PRK15439 267 PVLTVEDLTGE-----GFRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRLARGLv 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 414 -----RR----------TWQT-----------TRIAPELRVGDYIRLAAGpigqtelesllgwFGCPPPETPIASVDAGT 467
Cdd:PRK15439 342 ylpedRQssglyldaplAWNVcalthnrrgfwIKPARENAVLERYRRALN-------------IKFNHAEQAARTLSGGN 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 468 RRLLDVAGAVASRAPVILLDEPAAGI---SYDEALKLGERIAAIpatfGSAVLLIEHDMDLVRRACTAITVFDFGQViaS 544
Cdd:PRK15439 409 QQKVLIAKCLEASPQLLIVDEPTRGVdvsARNDIYQLIRSIAAQ----NVAVLFISSDLEEIEQMADRVLVMHQGEI--S 482
|
....
gi 492864881 545 GEPA 548
Cdd:PRK15439 483 GALT 486
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
352-398 |
1.42e-04 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 45.11 E-value: 1.42e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 492864881 352 LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLP-RYDGTVLLHGK 398
Cdd:PLN03130 633 LSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPpRSDASVVIRGT 680
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
336-384 |
1.52e-04 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 43.41 E-value: 1.52e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 492864881 336 VLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAG 384
Cdd:COG2401 30 VLEAFGVELRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAG 78
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
333-555 |
1.56e-04 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 44.46 E-value: 1.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 333 EGTVLEVRDLTVRY----GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTV-----LLHGKPLEAL 403
Cdd:PRK10261 9 ARDVLAVENLNIAFmqeqQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVqcdkmLLRRRSRQVI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 404 SATARAKAGIRRT--------WQ--TTRIAPELRVGDYI----RLAAGPIGQTEL---ESLLGWFGCPPPETPIA----S 462
Cdd:PRK10261 89 ELSEQSAAQMRHVrgadmamiFQepMTSLNPVFTVGEQIaesiRLHQGASREEAMveaKRMLDQVRIPEAQTILSryphQ 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 463 VDAGTRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLIEHDMDLVRRACTAITVFDFGQVI 542
Cdd:PRK10261 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAV 248
|
250
....*....|...
gi 492864881 543 ASGEPAEVLDMPE 555
Cdd:PRK10261 249 ETGSVEQIFHAPQ 261
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
355-413 |
1.67e-04 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 44.52 E-value: 1.67e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 355 VNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEALSATARAKAGI 413
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAGI 330
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
362-395 |
1.96e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 41.98 E-value: 1.96e-04
10 20 30
....*....|....*....|....*....|....
gi 492864881 362 GTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLL 395
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIY 35
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
335-493 |
2.30e-04 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 43.95 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTvrygavtALNK-----VNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLE---ALSAT 406
Cdd:PRK10982 249 VILEVRNLT-------SLRQpsirdVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINnhnANEAI 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 407 ARAKAGIRRTWQTTRIAPELRVG--------DYIRLAAGPIGQTELESLLGWF------GCPPPETPIASVDAGTRRLLD 472
Cdd:PRK10982 322 NHGFALVTEERRSTGIYAYLDIGfnslisniRNYKNKVGLLDNSRMKSDTQWVidsmrvKTPGHRTQIGSLSGGNQQKVI 401
|
170 180
....*....|....*....|.
gi 492864881 473 VAGAVASRAPVILLDEPAAGI 493
Cdd:PRK10982 402 IGRWLLTQPEILMLDEPTRGI 422
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
323-521 |
2.78e-04 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 42.53 E-value: 2.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 323 ALANSAPAIgegtvLEVRDLTVRYGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPlea 402
Cdd:PRK13543 3 EPLHTAPPL-----LAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKT--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 403 lsatarakagIRRTWQTTRIApelRVGDYIRLAAGPIGQTELESLLGWFGCPPPETP----------------IASVDAG 466
Cdd:PRK13543 75 ----------ATRGDRSRFMA---YLGHLPGLKADLSTLENLHFLCGLHGRRAKQMPgsalaivglagyedtlVRQLSAG 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 467 TRRLLDVAGAVASRAPVILLDEPAAGISYdEALKLGERIAAIPATFGSAVLLIEH 521
Cdd:PRK13543 142 QKKRLALARLWLSPAPLWLLDEPYANLDL-EGITLVNRMISAHLRGGGAALVTTH 195
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
333-545 |
4.96e-04 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 43.03 E-value: 4.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 333 EGTVlEVRDLTVRY-GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVdaiaGFLPR-YD---GTVLLHGKPLEALSata 407
Cdd:PRK13657 332 KGAV-EFDDVSFSYdNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLI----NLLQRvFDpqsGRILIDGTDIRTVT--- 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 408 raKAGIRRTWQTT---------RIAPELRVG------DYIRLAAGPIGQTE--LESLLGWfgcpppETPIA----SVDAG 466
Cdd:PRK13657 404 --RASLRRNIAVVfqdaglfnrSIEDNIRVGrpdatdEEMRAAAERAQAHDfiERKPDGY------DTVVGergrQLSGG 475
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492864881 467 TRRLLDVAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIpaTFGSAVLLIEHDMDLVRRAcTAITVFDFGQVIASG 545
Cdd:PRK13657 476 ERQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDEL--MKGRTTFIIAHRLSTVRNA-DRILVFDNGRVVESG 551
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
354-386 |
5.07e-04 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 42.29 E-value: 5.07e-04
10 20 30
....*....|....*....|....*....|...
gi 492864881 354 KVNLTVPAGTVVgLVGPNGAGKSTLVDAIAGFL 386
Cdd:COG3950 18 EIDFDNPPRLTV-LVGENGSGKTTLLEAIALAL 49
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
485-550 |
5.43e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 43.08 E-value: 5.43e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492864881 485 LLDEPAAGISYDEALKLGERIAAIPATfGSAVLLIEHDMDLVRracTAITVFDF--------GQVIASGEPAEV 550
Cdd:TIGR00630 855 ILDEPTTGLHFDDIKKLLEVLQRLVDK-GNTVVVIEHNLDVIK---TADYIIDLgpeggdggGTVVASGTPEEV 924
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
346-542 |
5.60e-04 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 42.63 E-value: 5.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 346 YGAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLlhgkpLEALSATARAKAGIRRTWQTTriape 425
Cdd:PRK11147 13 FSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRII-----YEQDLIVARLQQDPPRNVEGT----- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 426 lrVGDYIrlAAGPIGQTEL----------------ESLL--------------GW------------FGCpPPETPIASV 463
Cdd:PRK11147 83 --VYDFV--AEGIEEQAEYlkryhdishlvetdpsEKNLnelaklqeqldhhnLWqlenrinevlaqLGL-DPDAALSSL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 464 DAGTRRLLDVAGAVASRAPVILLDEPA-----AGISYDEALKLgeriaaipaTFGSAVLLIEHDMDLVRRACTAITVFDF 538
Cdd:PRK11147 158 SGGWLRKAALGRALVSNPDVLLLDEPTnhldiETIEWLEGFLK---------TFQGSIIFISHDRSFIRNMATRIVDLDR 228
|
....
gi 492864881 539 GQVI 542
Cdd:PRK11147 229 GKLV 232
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
352-401 |
5.81e-04 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 41.07 E-value: 5.81e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 492864881 352 LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGflpRYD-----GTVLLHGKPLE 401
Cdd:cd03232 23 LNNISGYVKPGTLTALMGESGAGKTTLLDVLAG---RKTagvitGEILINGRPLD 74
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
357-535 |
8.14e-04 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 40.42 E-value: 8.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 357 LTVPAGTVVGLVGPNGAGKSTLVDAIAgflprydgtVLLHGKplealSATARAKAGIRRTWQTTRIAPELRVGDyIRLAA 436
Cdd:cd03227 16 VTFGEGSLTIITGPNGSGKSTILDAIG---------LALGGA-----QSATRRRSGVKAGCIVAAVSAELIFTR-LQLSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 437 GPIGQTELESLLGwfgcpppetpIASVDagtrrlldvagavasRAPVILLDEPAAGISYDEALKLGERIAAIpATFGSAV 516
Cdd:cd03227 81 GEKELSALALILA----------LASLK---------------PRPLYILDEIDRGLDPRDGQALAEAILEH-LVKGAQV 134
|
170
....*....|....*....
gi 492864881 517 LLIEHDMDLVRRACTAITV 535
Cdd:cd03227 135 IVITHLPELAELADKLIHI 153
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
337-384 |
9.75e-04 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 41.75 E-value: 9.75e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 492864881 337 LEVRDLTVRY-GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAG 384
Cdd:PRK11650 4 LKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAG 52
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
352-489 |
1.07e-03 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 41.64 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 352 LNKVNLTVPAGTVV--------------GLVGPNGAGKSTLVDAIAGFLPRYDGtvllhgkplealsaTARAKAGIRRTW 417
Cdd:PRK11819 9 MNRVSKVVPPKKQIlkdislsffpgakiGVLGLNGAGKSTLLRIMAGVDKEFEG--------------EARPAPGIKVGY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 418 --QTTRIAPELRVGDYIRLAAGPIG--------------------------QTELESLL----GW------------FGC 453
Cdd:PRK11819 75 lpQEPQLDPEKTVRENVEEGVAEVKaaldrfneiyaayaepdadfdalaaeQGELQEIIdaadAWdldsqleiamdaLRC 154
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 492864881 454 PPPETPIASVDAGTRR-------LLdvagavaSRAPVILLDEP 489
Cdd:PRK11819 155 PPWDAKVTKLSGGERRrvalcrlLL-------EKPDMLLLDEP 190
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
332-402 |
1.38e-03 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 40.89 E-value: 1.38e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492864881 332 GEGTVLEVRDLTVRYGAVTA--LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKPLEA 402
Cdd:PRK13648 3 DKNSIIVFKNVSFQYQSDASftLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITD 75
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
335-418 |
1.50e-03 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 41.10 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 335 TVLEVRDLTVRY----------GAVTALNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVLLHGKplEALS 404
Cdd:PRK11308 4 PLLQAIDLKKHYpvkrglfkpeRLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQ--DLLK 81
|
90
....*....|....
gi 492864881 405 ATARAKAGIRRTWQ 418
Cdd:PRK11308 82 ADPEAQKLLRQKIQ 95
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
356-386 |
1.50e-03 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 41.31 E-value: 1.50e-03
10 20 30
....*....|....*....|....*....|..
gi 492864881 356 NLTVP-AGTVVGLVGPNGAGKSTLVDAIAGFL 386
Cdd:COG1245 92 GLPVPkKGKVTGILGPNGIGKSTALKILSGEL 123
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
341-384 |
1.72e-03 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 41.33 E-value: 1.72e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 492864881 341 DLTVRYGaVTALNKVNLTVP-AGTVVGLVGPNGAGKSTLVDAIAG 384
Cdd:PRK13409 78 EPVHRYG-VNGFKLYGLPIPkEGKVTGILGPNGIGKTTAVKILSG 121
|
|
| COG3910 |
COG3910 |
Predicted ATPase [General function prediction only]; |
348-388 |
2.23e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443116 [Multi-domain] Cd Length: 239 Bit Score: 39.75 E-value: 2.23e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 492864881 348 AVTALNKVNLTVPagtVVGLVGPNGAGKSTLVDAIA---GFLPR 388
Cdd:COG3910 26 AVRNLEGLEFHPP---VTFFVGENGSGKSTLLEAIAvaaGFNPE 66
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
352-386 |
3.53e-03 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 39.99 E-value: 3.53e-03
10 20 30
....*....|....*....|....*....|....*
gi 492864881 352 LNKVNLTVPAGTVVgLVGPNGAGKSTLVDAIAGFL 386
Cdd:COG3593 14 IKDLSIELSDDLTV-LVGENNSGKSSILEALRLLL 47
|
|
| AAA_23 |
pfam13476 |
AAA domain; |
364-390 |
3.67e-03 |
|
AAA domain;
Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 39.02 E-value: 3.67e-03
10 20 30
....*....|....*....|....*....|.
gi 492864881 364 VVGLVGPNGAGKSTLVDAIA----GFLPRYD 390
Cdd:pfam13476 20 LTLITGPNGSGKTTILDAIKlalyGKTSRLK 50
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
364-383 |
4.32e-03 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 38.84 E-value: 4.32e-03
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
354-382 |
4.50e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 40.04 E-value: 4.50e-03
10 20
....*....|....*....|....*....
gi 492864881 354 KVNLTVPAGtVVGLVGPNGAGKSTLVDAI 382
Cdd:TIGR02168 16 PTTINFDKG-ITGIVGPNGCGKSNIVDAI 43
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
367-383 |
4.56e-03 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 35.65 E-value: 4.56e-03
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
356-386 |
4.76e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 39.53 E-value: 4.76e-03
10 20 30
....*....|....*....|....*....|.
gi 492864881 356 NLTVPAGTVVGLVGPNGAGKSTLVDAIaGFL 386
Cdd:COG4637 15 DLELPLGPLTVLIGANGSGKSNLLDAL-RFL 44
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
352-397 |
4.97e-03 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 39.96 E-value: 4.97e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 492864881 352 LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRY-DGTVLLHG 397
Cdd:PLN03232 633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAeTSSVVIRG 679
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
352-392 |
5.21e-03 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 39.73 E-value: 5.21e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 492864881 352 LNKVNLTVPAGTVVGLVGPNGAGKSTLVDAIAGFLPRYDGT 392
Cdd:TIGR00954 468 IESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGR 508
|
|
| ABC_SMC_barmotin |
cd03278 |
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ... |
354-382 |
6.50e-03 |
|
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213245 [Multi-domain] Cd Length: 197 Bit Score: 38.21 E-value: 6.50e-03
10 20
....*....|....*....|....*....
gi 492864881 354 KVNLTVPAGtVVGLVGPNGAGKSTLVDAI 382
Cdd:cd03278 15 KTTIPFPPG-LTAIVGPNGSGKSNIIDAI 42
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
362-548 |
8.80e-03 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 37.55 E-value: 8.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 362 GTVVGLVGPNGAGKSTLVDAIAGFLPRYDGTVllhgkplealsatarakagirrTWQTTRIA--PElrvgdYIRLAAGPI 439
Cdd:cd03222 25 GEVIGIVGPNGTGKTTAVKILAGQLIPNGDND----------------------EWDGITPVykPQ-----YIDLSGGEL 77
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492864881 440 GQTELesllgwfgcpppetpiasvdagtrrlldvAGAVASRAPVILLDEPAAGISYDEALKLGERIAAIPATFGSAVLLI 519
Cdd:cd03222 78 QRVAI-----------------------------AAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVV 128
|
170 180
....*....|....*....|....*....
gi 492864881 520 EHDMDLVRRACTAITVFDfgqviasGEPA 548
Cdd:cd03222 129 EHDLAVLDYLSDRIHVFE-------GEPG 150
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|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
367-383 |
9.31e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 39.13 E-value: 9.31e-03
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
364-391 |
9.61e-03 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 38.52 E-value: 9.61e-03
10 20
....*....|....*....|....*...
gi 492864881 364 VVGLVGPNGAGKSTLVDAIAgFLPRYDG 391
Cdd:pfam13304 1 INVLIGPNGSGKSNLLEALR-FLADFDA 27
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