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Conserved domains on  [gi|493226325|ref|WP_006204404|]
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hypothetical protein [Brucella suis]

Protein Classification

Ig-like domain-containing protein( domain architecture ID 581445)

bacterial immunoglobulin (Ig)-like domain-containing protein may be a cell surface protein and may play a vital role in host-pathogen interactions; similar to Bacteroides fragilis putative transglutaminase-family protein

CATH:  2.60.40.10
PubMed:  9417933|33355339|10436082|34986320|7932691|22724448
SCOP:  3000070

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Invasin_D3 super family cl23771
Invasin, domain 3; Members of this family adopt a structure consisting of an ...
 122-218 3.88e-06

Invasin, domain 3; Members of this family adopt a structure consisting of an immunoglobulin-like beta-sandwich, with seven strands in two beta-sheets, arranged in a Greek-key topology. It forms part of the extracellular region of the protein, which can be expressed as a soluble protein (Inv497) that binds integrins and promotes subsequent uptake by cells when attached to bacteria.


The actual alignment was detected with superfamily member smart00634:

Pssm-ID: 474048 [Multi-domain]  Cd Length: 92  Bit Score: 45.01  E-value: 3.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493226325   122 VLKLKVDKDNALSNGTDFDLVTATLTRDGGQKFVGQGVTFSLPSNDAAVFETGqtkklSATTGNDGTATAIIIRNAAggG 201
Cdd:smart00634   2 VTTLTADKDTAVANGSDAITLTATVTDANGNPVAGQEVTFTTPSGGALTLSKG-----TATTDANGIATVTLTSTTA--G 74

                           90
                   ....*....|....*..
gi 493226325   202 TVTVTCVLDADGKVSDQ 218
Cdd:smart00634  75 VYTVTASLENGSSSVKQ 91
 
Name Accession Description Interval E-value
BID_1 smart00634
Bacterial Ig-like domain (group 1);
122-218 3.88e-06

Bacterial Ig-like domain (group 1);


Pssm-ID: 214751 [Multi-domain]  Cd Length: 92  Bit Score: 45.01  E-value: 3.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493226325   122 VLKLKVDKDNALSNGTDFDLVTATLTRDGGQKFVGQGVTFSLPSNDAAVFETGqtkklSATTGNDGTATAIIIRNAAggG 201
Cdd:smart00634   2 VTTLTADKDTAVANGSDAITLTATVTDANGNPVAGQEVTFTTPSGGALTLSKG-----TATTDANGIATVTLTSTTA--G 74

                           90
                   ....*....|....*..
gi 493226325   202 TVTVTCVLDADGKVSDQ 218
Cdd:smart00634  75 VYTVTASLENGSSSVKQ 91
 
Name Accession Description Interval E-value
BID_1 smart00634
Bacterial Ig-like domain (group 1);
122-218 3.88e-06

Bacterial Ig-like domain (group 1);


Pssm-ID: 214751 [Multi-domain]  Cd Length: 92  Bit Score: 45.01  E-value: 3.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493226325   122 VLKLKVDKDNALSNGTDFDLVTATLTRDGGQKFVGQGVTFSLPSNDAAVFETGqtkklSATTGNDGTATAIIIRNAAggG 201
Cdd:smart00634   2 VTTLTADKDTAVANGSDAITLTATVTDANGNPVAGQEVTFTTPSGGALTLSKG-----TATTDANGIATVTLTSTTA--G 74

                           90
                   ....*....|....*..
gi 493226325   202 TVTVTCVLDADGKVSDQ 218
Cdd:smart00634  75 VYTVTASLENGSSSVKQ 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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