|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11128 |
PRK11128 |
3-phenylpropionate MFS transporter; |
1-379 |
0e+00 |
|
3-phenylpropionate MFS transporter;
Pssm-ID: 236856 [Multi-domain] Cd Length: 382 Bit Score: 531.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 1 MVIPSTRWLAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLINGLRLLAALS 80
Cdd:PRK11128 1 MVLQPTRWLALSYFGYFFAYGVFLPFWSVWLKGQGYTPETIGLLLGAGLVARFLGSLLIAPRVKDPSQLIPALRLLALLT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 81 LIFSIGFSFGSHWAWLMFVMIG-FNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSI 159
Cdd:PRK11128 81 LLFAVAFWFGAHSFWLLFVAIGlFNLFFSPLVPLTDALANTWQKQIGLDYGKVRLWGSIAFVIGSALTGKLVSWFGEQAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 160 MVALVISCAALLFGAMLKPAIMPAGVAK-TEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDL 238
Cdd:PRK11128 161 LWILTAGVASMLLGQLLRPTIMPQGESRqQESAGWPAWKALLKEPTVWRFLLCVSLLQGSHAAYYGFSAIYWQAAGYSAS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 239 VIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISA 318
Cdd:PRK11128 241 TIGYLWSLGVVAEVLIFAFSNRLFRRWSARDLLLLSAICGVVRWGLMGSTTALPWLIVIQILHCGTFTVCHLAAMRYIAA 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 493708990 319 RKENEIIPLQGAYSALATGGGLAVITIMVGYIYERMPdqhGVVFYLMALLAVPALFIRPKV 379
Cdd:PRK11128 321 RPGSEVIRLQALYSALAMGGSIAIMTVLSGFLYQHLG---AGVFWVMALVALPALFIRPKV 378
|
|
| 2A0127 |
TIGR00902 |
phenyl proprionate permease family protein; This family of proteins is involved in the uptake ... |
1-379 |
1.87e-125 |
|
phenyl proprionate permease family protein; This family of proteins is involved in the uptake of 3-phenylpropionic acid. This uptake mechanism is for the metabolism of phenylpropanoid compounds and plays an important role in the natural degradative cycle of these aromatic molecules. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 129980 Cd Length: 382 Bit Score: 366.56 E-value: 1.87e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 1 MVIPSTRWLAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLINGLRLLAALS 80
Cdd:TIGR00902 1 MQLQPFRWLALGFFGYFCAYGIFLPFFPAWLKGIGLGEEMIGLLIGAALIARFAGGLFFAPLIKDANHIIIALRLLALAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 81 LIFSIGFSFGSHWAWLMFVMIG-FNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSI 159
Cdd:TIGR00902 81 AIFAAAFSAGAHNAWLLFIAIGlFALFFSAGMPIGDALANTWQKQFGLDYGKVRLIGSAAFIIGSALFGGLIGMFDEQNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 160 MVALVISCAALLFGAMLKPAIMPAG-VAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDL 238
Cdd:TIGR00902 161 LAILTAGLAFMLIGFLIKPTIPPKDaIPEDESQGDSAFIALLKNPMNLRFLAAVCLIQGAHAAYYGFSAIYWQAAGISAS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 239 VIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISA 318
Cdd:TIGR00902 241 ATGLLWGIGVLAEIIIFAFSNKLFQNCSARDLLLISAIACVGRWAIIGAIEAFPLIFLLQILHCGTFAVCHLAAMRYIAA 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 493708990 319 RKENEIIPLQGAYSALATGGGLAVITIMVGYIYERMPdqhGVVFYLMALLAVPALFIRPKV 379
Cdd:TIGR00902 321 QPGSEIAKLQALYNALAMGGLIAIFTAFAGFIYPTLG---AGTFVFMAIIAAAAFFLIPKK 378
|
|
| MFS_MFSD6 |
cd17335 |
Major facilitator superfamily domain-containing protein 6; Human Major facilitator superfamily ... |
8-378 |
5.92e-71 |
|
Major facilitator superfamily domain-containing protein 6; Human Major facilitator superfamily domain-containing protein 6 (MFSD6) is also called macrophage MHC class I receptor 2 homolog (MMR2). It has been postulated as a possible receptor for human leukocyte antigen (HLA)-B62. MFSD6 is conserved through evolution and appeared before bilateral animals. It belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340893 [Multi-domain] Cd Length: 375 Bit Score: 226.70 E-value: 5.92e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 8 WLAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLINGLRLLAALSLIFSIGF 87
Cdd:cd17335 1 RLKLFYFFFFAALGSLLPFLSVYLKQLGLSPTQIGILIGIRPFVRFLSAPLWGALADRFGKRKALLLLSLLAAVLFFLSL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 88 SFGSH-WAWLMFVMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVALVIS 166
Cdd:cd17335 81 FFVAQiFWLLLLLVILGAFFSAPVVPLVDSITLQYLGEERERYGKQRLWGSIGFGIAALLVGILIDRSSTYKNYTIAFYV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 167 CAALLFGAMLKPAIMPAG-VAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDLVIGNLWS 245
Cdd:cd17335 161 FAVLMLLALLLALKFPFRpKHPEPNENTGGLLALLRNPRVLAFLLVAFLMGFGHGLIYSFLFWHLQDLGGSKTLIGLLWT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 246 LGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISARKENEI- 324
Cdd:cd17335 241 VGVVSEIPFFFFSSRLIQRFGHVGLLYLGLLAYVVRWLLYSFLENPWLVLPIELLHGLTFALVWAAAVSYASAAAPPGLr 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 493708990 325 IPLQGAYSALATGGGLAVITIMVGYIYERMPDQHGVVFY-LMALLAVPALFIRPK 378
Cdd:cd17335 321 ATAQGLLQGLYFGLGGGLGSLIGGYLYEAFGARTTFRFFaIAALAGLLAFFLIQR 375
|
|
| MFS_1_like |
pfam12832 |
MFS_1 like family; This family contains proteins related to the MFS superfamily. |
8-352 |
8.61e-49 |
|
MFS_1 like family; This family contains proteins related to the MFS superfamily.
Pssm-ID: 432817 [Multi-domain] Cd Length: 362 Bit Score: 168.58 E-value: 8.61e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 8 WLAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLINGLRLLAALSLIFSIGF 87
Cdd:pfam12832 3 RLKGFYFFYFAALGCLLPYWGLYLRSIGLNPSEIGLITAILPLTRILAPPIWGWLADRTGKRKAVVRLASILAAVLFLSV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 88 ---SFGSHWAWLMFVMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVALV 164
Cdd:pfam12832 83 lfiPISLTFWWLALLVVLFSFFWNAILPQFEVATLQHLGEKRKDYGRQRLWGSVGFALSVFGLGALFDHYSVGLLPSVLF 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 165 ISCAALLFGAMLKPAIMPAGVAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDLVIGNLW 244
Cdd:pfam12832 163 YLFAALMLLSLLLPLAPPEMEYESKGGSKAVFWNLLKQPEVIIFFLAAFLLGFSHGPFYTFLFLYLENLGASNTLLGALW 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 245 SLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALP-VLIIVQVLHSGTFTVCHLAAMRFISARKENE 323
Cdd:pfam12832 243 ALGVVAEIPLFFYAHRLLRRFGHRNLLIIALLLTALRWLLYAFFVENPwLVLPIQFLHAISFGLTHAAAIEYVRRIFPGS 322
|
330 340 350
....*....|....*....|....*....|
gi 493708990 324 IIP-LQGAYSALATGGGLAVITIMVGYIYE 352
Cdd:pfam12832 323 LQGtGQALYSGLYFGLGGALGSLIGGQLWD 352
|
|
| mfs |
NF037955 |
MFS transporter; |
9-373 |
9.36e-39 |
|
MFS transporter;
Pssm-ID: 411561 [Multi-domain] Cd Length: 366 Bit Score: 142.10 E-value: 9.36e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 9 LAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAmfiTPQVKEPSKLINGLRLLAALSLIFSIGFS 88
Cdd:NF037955 2 LSLLYAVVFVEIGIAMPFMPVWLEALGLDAGVIGLLLALPIAVRIVAT---APLMSLIDRGVGARRLLLAGSLGLALTYA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 89 F---GSHWAW-LMFVMIGFNLFF-APMVPLGDSLA-GTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVA 162
Cdd:NF037955 79 LmpaAAALGWpLLALLVALNAVAqAPLVPSIDYLTlAAVRRDPRLDYARIRMSGSVAFLAANLAGGALLGALGERVAVPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 163 LViscAALLFGAMLKPAIMPAGVAKTEGTNKVSFKQLIAdKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDLVIGN 242
Cdd:NF037955 159 LL---TGLALVAALVALASRVRAAAAPPRPREAGRPRLP-RVLWLAIAAGAAIQASHAAIYAFGSIHWRAHGISTAWIGA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 243 LWSLGVVAEVIVFMLSHRLFRRW-SARNLLLLSAVCGIIRW-GMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISA-R 319
Cdd:NF037955 235 LWAIGVVAEIVLFALLGRLPARWrTPFRLLGLGAAAALVRAiGMALLGGTLAAVVPLQALHGLTFGATQLGAMAAVSAfA 314
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 493708990 320 KENEIIPLQGAYSALATGGGlAVITIMVGYIYERMPdqhGVVFYLMALLAVPAL 373
Cdd:NF037955 315 PEGARGRAQGTYSAANALAS-ASATLASGLAYRAGG---PLAFALMAPLALIGL 364
|
|
| AraJ |
COG2814 |
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism]; |
9-339 |
4.43e-11 |
|
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];
Pssm-ID: 442063 [Multi-domain] Cd Length: 348 Bit Score: 63.45 E-value: 4.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 9 LAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPqvkePSKLINGLRLLAALSLIF---SI 85
Cdd:COG2814 15 LALGAFLSGLGIGIVLPALPLIAADLGASPAQAGLVVTAYLLGAALGAPLAGR----LADRFGRRRVLLLGLLLFalgSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 86 GFSFGSHWAWLMFVMIGFNLFFAPMVPLGDSLAGTW--QKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVAL 163
Cdd:COG2814 91 LCALAPSLWLLLAARFLQGLGAGALFPAALALIADLvpPERRGRALGLLGAGLGLGPALGPLLGGLLADLFGWRWVFLVN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 164 VISCAALLFGAMLkpaIMPAGVAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKE-AGYSDLVIGN 242
Cdd:COG2814 171 AVLALLALLLLLR---LLPESRPAARARLRGSLRELLRRPRLLLLLLLAFLLGFGFFALFTYLPLYLQEvLGLSASAAGL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 243 LWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISARKEN 322
Cdd:COG2814 248 LLALFGLGGVLGALLAGRLADRFGRRRLLLIGLLLLALGLLLLALAGSLWLLLLALFLLGFGFGLLFPLLQALVAELAPP 327
|
330
....*....|....*...
gi 493708990 323 EIIPL-QGAYSALATGGG 339
Cdd:COG2814 328 EARGRaSGLYNSAFFLGG 345
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11128 |
PRK11128 |
3-phenylpropionate MFS transporter; |
1-379 |
0e+00 |
|
3-phenylpropionate MFS transporter;
Pssm-ID: 236856 [Multi-domain] Cd Length: 382 Bit Score: 531.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 1 MVIPSTRWLAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLINGLRLLAALS 80
Cdd:PRK11128 1 MVLQPTRWLALSYFGYFFAYGVFLPFWSVWLKGQGYTPETIGLLLGAGLVARFLGSLLIAPRVKDPSQLIPALRLLALLT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 81 LIFSIGFSFGSHWAWLMFVMIG-FNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSI 159
Cdd:PRK11128 81 LLFAVAFWFGAHSFWLLFVAIGlFNLFFSPLVPLTDALANTWQKQIGLDYGKVRLWGSIAFVIGSALTGKLVSWFGEQAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 160 MVALVISCAALLFGAMLKPAIMPAGVAK-TEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDL 238
Cdd:PRK11128 161 LWILTAGVASMLLGQLLRPTIMPQGESRqQESAGWPAWKALLKEPTVWRFLLCVSLLQGSHAAYYGFSAIYWQAAGYSAS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 239 VIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISA 318
Cdd:PRK11128 241 TIGYLWSLGVVAEVLIFAFSNRLFRRWSARDLLLLSAICGVVRWGLMGSTTALPWLIVIQILHCGTFTVCHLAAMRYIAA 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 493708990 319 RKENEIIPLQGAYSALATGGGLAVITIMVGYIYERMPdqhGVVFYLMALLAVPALFIRPKV 379
Cdd:PRK11128 321 RPGSEVIRLQALYSALAMGGSIAIMTVLSGFLYQHLG---AGVFWVMALVALPALFIRPKV 378
|
|
| 2A0127 |
TIGR00902 |
phenyl proprionate permease family protein; This family of proteins is involved in the uptake ... |
1-379 |
1.87e-125 |
|
phenyl proprionate permease family protein; This family of proteins is involved in the uptake of 3-phenylpropionic acid. This uptake mechanism is for the metabolism of phenylpropanoid compounds and plays an important role in the natural degradative cycle of these aromatic molecules. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 129980 Cd Length: 382 Bit Score: 366.56 E-value: 1.87e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 1 MVIPSTRWLAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLINGLRLLAALS 80
Cdd:TIGR00902 1 MQLQPFRWLALGFFGYFCAYGIFLPFFPAWLKGIGLGEEMIGLLIGAALIARFAGGLFFAPLIKDANHIIIALRLLALAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 81 LIFSIGFSFGSHWAWLMFVMIG-FNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSI 159
Cdd:TIGR00902 81 AIFAAAFSAGAHNAWLLFIAIGlFALFFSAGMPIGDALANTWQKQFGLDYGKVRLIGSAAFIIGSALFGGLIGMFDEQNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 160 MVALVISCAALLFGAMLKPAIMPAG-VAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDL 238
Cdd:TIGR00902 161 LAILTAGLAFMLIGFLIKPTIPPKDaIPEDESQGDSAFIALLKNPMNLRFLAAVCLIQGAHAAYYGFSAIYWQAAGISAS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 239 VIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISA 318
Cdd:TIGR00902 241 ATGLLWGIGVLAEIIIFAFSNKLFQNCSARDLLLISAIACVGRWAIIGAIEAFPLIFLLQILHCGTFAVCHLAAMRYIAA 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 493708990 319 RKENEIIPLQGAYSALATGGGLAVITIMVGYIYERMPdqhGVVFYLMALLAVPALFIRPKV 379
Cdd:TIGR00902 321 QPGSEIAKLQALYNALAMGGLIAIFTAFAGFIYPTLG---AGTFVFMAIIAAAAFFLIPKK 378
|
|
| MFS_MFSD6 |
cd17335 |
Major facilitator superfamily domain-containing protein 6; Human Major facilitator superfamily ... |
8-378 |
5.92e-71 |
|
Major facilitator superfamily domain-containing protein 6; Human Major facilitator superfamily domain-containing protein 6 (MFSD6) is also called macrophage MHC class I receptor 2 homolog (MMR2). It has been postulated as a possible receptor for human leukocyte antigen (HLA)-B62. MFSD6 is conserved through evolution and appeared before bilateral animals. It belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340893 [Multi-domain] Cd Length: 375 Bit Score: 226.70 E-value: 5.92e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 8 WLAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLINGLRLLAALSLIFSIGF 87
Cdd:cd17335 1 RLKLFYFFFFAALGSLLPFLSVYLKQLGLSPTQIGILIGIRPFVRFLSAPLWGALADRFGKRKALLLLSLLAAVLFFLSL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 88 SFGSH-WAWLMFVMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVALVIS 166
Cdd:cd17335 81 FFVAQiFWLLLLLVILGAFFSAPVVPLVDSITLQYLGEERERYGKQRLWGSIGFGIAALLVGILIDRSSTYKNYTIAFYV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 167 CAALLFGAMLKPAIMPAG-VAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDLVIGNLWS 245
Cdd:cd17335 161 FAVLMLLALLLALKFPFRpKHPEPNENTGGLLALLRNPRVLAFLLVAFLMGFGHGLIYSFLFWHLQDLGGSKTLIGLLWT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 246 LGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISARKENEI- 324
Cdd:cd17335 241 VGVVSEIPFFFFSSRLIQRFGHVGLLYLGLLAYVVRWLLYSFLENPWLVLPIELLHGLTFALVWAAAVSYASAAAPPGLr 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 493708990 325 IPLQGAYSALATGGGLAVITIMVGYIYERMPDQHGVVFY-LMALLAVPALFIRPK 378
Cdd:cd17335 321 ATAQGLLQGLYFGLGGGLGSLIGGYLYEAFGARTTFRFFaIAALAGLLAFFLIQR 375
|
|
| MFS_1_like |
pfam12832 |
MFS_1 like family; This family contains proteins related to the MFS superfamily. |
8-352 |
8.61e-49 |
|
MFS_1 like family; This family contains proteins related to the MFS superfamily.
Pssm-ID: 432817 [Multi-domain] Cd Length: 362 Bit Score: 168.58 E-value: 8.61e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 8 WLAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLINGLRLLAALSLIFSIGF 87
Cdd:pfam12832 3 RLKGFYFFYFAALGCLLPYWGLYLRSIGLNPSEIGLITAILPLTRILAPPIWGWLADRTGKRKAVVRLASILAAVLFLSV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 88 ---SFGSHWAWLMFVMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVALV 164
Cdd:pfam12832 83 lfiPISLTFWWLALLVVLFSFFWNAILPQFEVATLQHLGEKRKDYGRQRLWGSVGFALSVFGLGALFDHYSVGLLPSVLF 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 165 ISCAALLFGAMLKPAIMPAGVAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDLVIGNLW 244
Cdd:pfam12832 163 YLFAALMLLSLLLPLAPPEMEYESKGGSKAVFWNLLKQPEVIIFFLAAFLLGFSHGPFYTFLFLYLENLGASNTLLGALW 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 245 SLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALP-VLIIVQVLHSGTFTVCHLAAMRFISARKENE 323
Cdd:pfam12832 243 ALGVVAEIPLFFYAHRLLRRFGHRNLLIIALLLTALRWLLYAFFVENPwLVLPIQFLHAISFGLTHAAAIEYVRRIFPGS 322
|
330 340 350
....*....|....*....|....*....|
gi 493708990 324 IIP-LQGAYSALATGGGLAVITIMVGYIYE 352
Cdd:pfam12832 323 LQGtGQALYSGLYFGLGGALGSLIGGQLWD 352
|
|
| mfs |
NF037955 |
MFS transporter; |
9-373 |
9.36e-39 |
|
MFS transporter;
Pssm-ID: 411561 [Multi-domain] Cd Length: 366 Bit Score: 142.10 E-value: 9.36e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 9 LAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAmfiTPQVKEPSKLINGLRLLAALSLIFSIGFS 88
Cdd:NF037955 2 LSLLYAVVFVEIGIAMPFMPVWLEALGLDAGVIGLLLALPIAVRIVAT---APLMSLIDRGVGARRLLLAGSLGLALTYA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 89 F---GSHWAW-LMFVMIGFNLFF-APMVPLGDSLA-GTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVA 162
Cdd:NF037955 79 LmpaAAALGWpLLALLVALNAVAqAPLVPSIDYLTlAAVRRDPRLDYARIRMSGSVAFLAANLAGGALLGALGERVAVPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 163 LViscAALLFGAMLKPAIMPAGVAKTEGTNKVSFKQLIAdKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDLVIGN 242
Cdd:NF037955 159 LL---TGLALVAALVALASRVRAAAAPPRPREAGRPRLP-RVLWLAIAAGAAIQASHAAIYAFGSIHWRAHGISTAWIGA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 243 LWSLGVVAEVIVFMLSHRLFRRW-SARNLLLLSAVCGIIRW-GMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISA-R 319
Cdd:NF037955 235 LWAIGVVAEIVLFALLGRLPARWrTPFRLLGLGAAAALVRAiGMALLGGTLAAVVPLQALHGLTFGATQLGAMAAVSAfA 314
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 493708990 320 KENEIIPLQGAYSALATGGGlAVITIMVGYIYERMPdqhGVVFYLMALLAVPAL 373
Cdd:NF037955 315 PEGARGRAQGTYSAANALAS-ASATLASGLAYRAGG---PLAFALMAPLALIGL 364
|
|
| MFS_NHS |
cd06177 |
Nucleoside:H(+) symporter family of the Major Facilitator Superfamily of transporters; The ... |
74-301 |
1.05e-14 |
|
Nucleoside:H(+) symporter family of the Major Facilitator Superfamily of transporters; The prototypical members of the Nucleoside:H(+) symporter (NHS) family are Escherichia coli nucleoside permease NupG and xanthosine permease. Nucleoside:H(+) symporters are proton-driven transporters that facilitate the import of nucleosides across the cytoplasmic membrane. NupG is a broad-specificity transporter of purine and pyrimidine nucleosides. Xanthosine permease is involved in the uptake of xanthosine and other nucleosides such as inosine, adenosine, cytidine, uridine and thymidine. The NHS family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340866 [Multi-domain] Cd Length: 386 Bit Score: 74.97 E-value: 1.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 74 RLLAALSLI--FSIGFSFGSHWAWLMF-VMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYF 150
Cdd:cd06177 65 KVLAVLHLIgaAALFYAATVTDFSVFFwVMLLYSLCYMPTLALTNSIAFSNLEDPVKDFPPIRVWGTIGWIAAGWPVGFL 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 151 AgvwGHTSIMVALVISCAALLFG--AMLKPAIMPAGVAKTEGTNKV----SFKqLIADKNVLMFLICVTLLQGAHAAYYG 224
Cdd:cd06177 145 G---WEASNLQFYIAAGASLLLGlySLTLPHTPPKKAGKGVSKRSLlgldAFV-LLKNPFFAVFFIFSFLLGAPLQFYYT 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 225 FASLFWKEAGYSDLVIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAF---TALPVLIIVQVLH 301
Cdd:cd06177 221 FANPFLNDFGMIVKNPAGIMSLGQISEILFMLAIPFFLKRLGIKKVMLIGMLAWVLRFGLFAYGdpsPGVWMLVLSIILH 300
|
|
| AraJ |
COG2814 |
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism]; |
9-339 |
4.43e-11 |
|
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];
Pssm-ID: 442063 [Multi-domain] Cd Length: 348 Bit Score: 63.45 E-value: 4.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 9 LAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPqvkePSKLINGLRLLAALSLIF---SI 85
Cdd:COG2814 15 LALGAFLSGLGIGIVLPALPLIAADLGASPAQAGLVVTAYLLGAALGAPLAGR----LADRFGRRRVLLLGLLLFalgSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 86 GFSFGSHWAWLMFVMIGFNLFFAPMVPLGDSLAGTW--QKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVAL 163
Cdd:COG2814 91 LCALAPSLWLLLAARFLQGLGAGALFPAALALIADLvpPERRGRALGLLGAGLGLGPALGPLLGGLLADLFGWRWVFLVN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 164 VISCAALLFGAMLkpaIMPAGVAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKE-AGYSDLVIGN 242
Cdd:COG2814 171 AVLALLALLLLLR---LLPESRPAARARLRGSLRELLRRPRLLLLLLLAFLLGFGFFALFTYLPLYLQEvLGLSASAAGL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 243 LWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISARKEN 322
Cdd:COG2814 248 LLALFGLGGVLGALLAGRLADRFGRRRLLLIGLLLLALGLLLLALAGSLWLLLLALFLLGFGFGLLFPLLQALVAELAPP 327
|
330
....*....|....*...
gi 493708990 323 EIIPL-QGAYSALATGGG 339
Cdd:COG2814 328 EARGRaSGLYNSAFFLGG 345
|
|
| MFS_MdtG_SLC18_like |
cd17325 |
bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator ... |
9-375 |
4.35e-09 |
|
bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters; This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340883 [Multi-domain] Cd Length: 375 Bit Score: 57.59 E-value: 4.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 9 LAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMF---ITPQVKEPSKLINGLRLLAALSLIFSi 85
Cdd:cd17325 1 LSLALFLDMLGYGIIIPILPLYAESLGASVAQIGLIVAAYALAQLLFSPPagrLSDRFGRKRLLLLGLLLLAVSTLLFA- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 86 gfsFGSHWAWLMFVMIGFNLFFAPMVPLGDSLAG--TWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTS---IM 160
Cdd:cd17325 80 ---FATSYWQLLLARFLQGLASAAVWPAAMALIAdiAPPEERGRAMGIFSSAIGLGFLIGPLLGGLLADALGYRApflVC 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 161 VALVISCAALLFGAMLKPAIMPAGVAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKE-AGYSDLV 239
Cdd:cd17325 157 AALALLALVLALLLLPEPRPPPNKRAVSAARLRSGLRLLLRDRRLLALFLAIFVLAFAFGALEPFLPLYAAElGGLSPAQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 240 IGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISAR 319
Cdd:cd17325 237 IGLLFGAQGLASALSQPPAGKLSDRIGRKPLILIGLLLSAVALLLLPLATSFWLLLLLLALLGLGLGLVFPATLALLADI 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 493708990 320 KENEIIPLQGAYSALATGGGLAVITIMVGYIYERMPdqHGVVFYLMALLAVPALFI 375
Cdd:cd17325 317 VPPEGRGTAMGLFNTAFSLGMVLGPLLGGFLYDAFG--FATPFLAAAALLLLAAVL 370
|
|
| Nuc_H_symport |
pfam03825 |
Nucleoside H+ symporter; |
95-309 |
5.05e-09 |
|
Nucleoside H+ symporter;
Pssm-ID: 461066 [Multi-domain] Cd Length: 399 Bit Score: 57.47 E-value: 5.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 95 WLMF-VMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSI--MVALVISCAALL 171
Cdd:pfam03825 92 EAFFlVILVNSLAYMPTLALTNSIAFANLQDPVTDFPPIRVWGTIGWIMASWPFVMWVVSLAGFELshMQLLIAAGLSAL 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 172 FG--AMLKPAIMPAGVAKTEGTNKVSFK--QLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDLVIGNLW-SL 246
Cdd:pfam03825 172 LVlfALTLPHTPAKQKANQSWTTLLGLDafALLKNKRMAVFFIFSFLLGAELQIYNVFANTFLTSFDKFIVKHASIImSL 251
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 493708990 247 GVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTA-LPVLIIVQVLHSGTFTVCH 309
Cdd:pfam03825 252 GQISEILFMLTLPFFLKRFGIKNVMLIGIVAWALRFAFFAYGADpTPFGTALLLLSMIVHGVAY 315
|
|
| MFS |
cd06174 |
Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse ... |
9-374 |
1.15e-08 |
|
Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.
Pssm-ID: 349949 [Multi-domain] Cd Length: 378 Bit Score: 56.28 E-value: 1.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 9 LAIDYFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKePSKLINGLRLLAALSLIFSIGFS 88
Cdd:cd06174 1 LLLGFFLTGLARGLISPLLPALLQSFGLSASQLGLLFALFSLGYALLQPLAGLLAD-RFGRRPVLLLGLLLFALGALLFA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 89 FGSHWAWLMFVMIGFNLFFAPMVPLGDSLAGTW--QKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVALVIS 166
Cdd:cd06174 80 FAPSFWLLLLGRFLLGLGSGLIDPAVLALIADLfpERERGRALGLLQAFGSVGGILGPLLGGILASSLGFGWRAVFLIAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 167 CAALLFGAML-------KPAIMPAGVAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKE-AGYSDL 238
Cdd:cd06174 160 ALALLAAILLllvvpdpPESARAKNEEASSKSVLKLLKRVLKNPGLWLLLLAIFLVNLAYYSFSTLLPLFLLDlGGLSVA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 239 VIGNLWSLGVVAEVIVFMLSHRLFRRWSAR-NLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFIS 317
Cdd:cd06174 240 VAGLLLSLFGLAGALGSLLLGLLSDRLIGRkPLLLIGLLLMALGLALLLLAPSLLLLLLLLLLLGFGLGGLLPLSFALIA 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 493708990 318 ARKENEIIPLQGAYSALATGGGLAVITIMVGYIYERMPDQHGVVFYLMALLAVPALF 374
Cdd:cd06174 320 ELFPPEIRGTAFGLLNTFGFLGGAIGPLLAGFLLAATFGLTGAFLVLAVLLLLAAIL 376
|
|
| MFS_Set |
cd17471 |
Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters; ... |
18-300 |
4.04e-08 |
|
Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters; This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341024 [Multi-domain] Cd Length: 371 Bit Score: 54.48 E-value: 4.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 18 FAYSIFLPFWSVWLQGEgidAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLINGLRLLAALSLIFS----IGFSFGSHW 93
Cdd:cd17471 10 LAGAFVLPYLSLFLTEE---LGASPLQIGIFMTLSALSGIVVSQWLGRLSDRGGDRKPLILLALLAGalgyLLFAFLRNY 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 94 AWLMFVMIGFNLFFAPMVPL--------GDSLAGTWQKQFTfdyGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIM-VALV 164
Cdd:cd17471 87 WVLLLVGVVLLSLGAAAFPQlfalareyADRSSGRDATLFN---SVLRAAFSLAWVIGPPLAFLLLDVLGFTGLFlLAAL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 165 ISCAALLFGAMLKPAIMPAgvaKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFW-KEAGYSDLVIGNL 243
Cdd:cd17471 164 LYLVVALLVLFLLPSVKPP---AQKATPASSLVKAPVNRRLLLLFAAFTLLFAANSMYIIAMPLYVtNELGGSESWVGLL 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 493708990 244 WSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVL 300
Cdd:cd17471 241 FGLAAALEIPIMLLAGLLAKRFGKRRLLLAGFLAGVLFYLGLALATSLWQLIALQLL 297
|
|
| MFS_MdtH_MDR_like |
cd17329 |
Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the ... |
7-378 |
7.07e-08 |
|
Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily; This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340887 [Multi-domain] Cd Length: 376 Bit Score: 53.77 E-value: 7.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 7 RWLAIDYFTYFFAYSIFLPFWSVWLQGE-GIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSK---LINGLRLLAALSLI 82
Cdd:cd17329 2 WVLLIGSFLNRLGFFMVWPFMAIYLHQQlGLSASIVGLVLALSAVAGIVASLIGGRLADRFGRkpvMLAGLLLRALGFAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 83 FSIGFSFGSHWAWLMFVMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYgkIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVA 162
Cdd:cd17329 82 LGFAHSPWLFAIALVLTGFGGGLFEPASEAMIADVTTPENRTRAFSL--LYWAINLGVAIGPLLGGLLLLYSFRLLFLAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 163 LVISCAALLFGAMLKPAIMPAGVAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAHAAYYGFASLFWKEA-GYSDLVIG 241
Cdd:cd17329 160 AVLFLLAALVLLFLLPETRPKRRAAEKTEILRGYKIVLRDRAFLLFLLASFLISLIYFQLESTLPVYVVEIlGLGESLLG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 242 NLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAMRFISARKE 321
Cdd:cd17329 240 LLLALNALLIVLLQFPVARLVERFRLRKILMIGILLFAIGFAVLAFANTLAVLILAMIVLTLGEMLVFPAVQTLVAALAP 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 493708990 322 NEIIPLQGAYSALATGGGLAVITIMVGYIYERMPDqhGVVFYLMALLAVPALFIRPK 378
Cdd:cd17329 320 PDKRGSYMGFYALAWGLGRAIGPLVGGLLLDLLGP--GLPWLILAALGLIAAALLLG 374
|
|
| MFS_LacY |
cd06172 |
LacY proton/sugar symporter family of the Major Facilitator Superfamily of transporters; LacY ... |
14-375 |
3.34e-07 |
|
LacY proton/sugar symporter family of the Major Facilitator Superfamily of transporters; LacY proton/sugar family (also called LacY/RafB family) symporters are integral membrane proteins responsible for the transport of specific beta-glucosides into the cell accompanied by the import of a proton. Members include lactose permease (LacY), raffinose permease (RafB), and sucrose permease, which facilitate the transport of beta-galactosides, raffinose, and sucrose, respectively. The prototypical member, LacY, contains 12 transmembrane helices connected by hydrophilic loops with both N and C termini on the cytoplasmic face. The LacY/RafB permease family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340862 [Multi-domain] Cd Length: 389 Bit Score: 51.85 E-value: 3.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 14 FTYFFAYSIFLPFWSVWLQGEGidaEMIGLLLGIGLAARFLGAMFITP-----QVKEPSK-----LINGLRLLAALSLIF 83
Cdd:cd06172 9 FLFFFIWSASFSFFPIWLTQIN---HLSGSETGIVFSANSLFALLFQPvygliSDKLGLKkhllwFISGLLVLFGPFFIF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 84 SIGFSFGSH-WAWLMFVMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHTSIMVA 162
Cdd:cd06172 86 VYGPLLQSNiLLGAIVGGIYLGFAFLAGCGAIESYIERVSRRFNFEYGRARMWGSLGWALAAFFAGILFNINPNINFWLG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 163 LVISCAALLFGAMLKPAIMPAGVAKTEGTNKVSFK---QLIADKNVLMFLI------CVTLLQGAHAAYYgFASLFWKEA 233
Cdd:cd06172 166 SGFALILLLLLLFAKPEDSDTAAAAGANASSVSLKdvlELFRMPKFWFFILfvigvsCFYDVFDQQFPPY-FTSLFATPE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 234 gYSDLVIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAM 313
Cdd:cd06172 245 -QGNRVFGYLNSAQVFLEAGMMFLAPLIVNRIGAKNGLLLAGTIMAVRIIGSGLATSPLEISILKLLHAFEVPLLLVSIF 323
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 493708990 314 RFISARKENEI---IPLQGaySALATGGGLAVITIMVGYIYERMPDQHgvVFYLMALLAVPALFI 375
Cdd:cd06172 324 KYITSHFDTRLsatLYLVG--FQFAKQLGAVVLSPLAGNLYDSIGFQQ--TYLVLGGIVLVFTLI 384
|
|
| MFS_1 |
pfam07690 |
Major Facilitator Superfamily; |
9-280 |
6.18e-06 |
|
Major Facilitator Superfamily;
Pssm-ID: 429598 [Multi-domain] Cd Length: 344 Bit Score: 47.80 E-value: 6.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 9 LAIDYFTYFFAYSIFLPFWSVWLQGE-GIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKLInGLRLLAALSLIFSIGF 87
Cdd:pfam07690 1 LFLAAFLAALGRSLLGPALPLLLAEDlGISPTEIGLLLTLFSLGYALAQPLAGRLSDRFGRRR-VLLIGLLLFALGLLLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 88 SFGSHWAWLMFVMIGFNLFFAPMVPLGDSLAGTW--QKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWG-HTSIMVALV 164
Cdd:pfam07690 80 LFASSLWLLLVLRVLQGLGAGALFPAALALIADWfpPEERGRALGLVSAGFGLGAALGPLLGGLLASLFGwRAAFLILAI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 165 ISCAALLFGAMLKPAIMPAGVAKTEGTNKVSFKQL--IADKNVLMFLICVTLLQGAHAAYYGFASLFWKEAGYSDLVIGN 242
Cdd:pfam07690 160 LSLLAAVLLLLPRPPPESKRPKPAEEARLSLIVAWkaLLRDPVLWLLLALLLFGFAFFGLLTYLPLYQEVLGLSALLAGL 239
|
250 260 270
....*....|....*....|....*....|....*...
gi 493708990 243 LWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGII 280
Cdd:pfam07690 240 LLGLGGLLGAIGRLLLGRLSDRLGRRRRLLLALLLLIL 277
|
|
| lacY |
PRK09528 |
galactoside permease; Reviewed |
13-375 |
2.87e-05 |
|
galactoside permease; Reviewed
Pssm-ID: 236549 Cd Length: 420 Bit Score: 45.66 E-value: 2.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 13 YFTYFFAYSIFLPFWSVWL-QGEGIDAEMIGLLLG-IGLAArfLGAMFITPQVKEpsKLinGLR--LLAALSLIfsiGFS 88
Cdd:PRK09528 19 FFFFFFIWSSWFSFFPIWLhDINGLSGTDTGIIFSaNSLFA--LLFQPLYGLISD--KL--GLKkhLLWIISGL---LVL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 89 FGSHWAWLMFVMIGFNLF-------------FAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSsmgyFAGV-W 154
Cdd:PRK09528 90 FGPFFIYVFAPLLQYNILlgaivggiylgfgFLAGAGAIEAYIERVSRRSGFEYGRARMWGSLGWALCAF----IAGIlF 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 155 GHTSIMVALVISCAALLFGAML---KPAIMP-AGVAKTEGTNK--VSFKQ---LIADKNVLMFLICVTLLqgahAAYYG- 224
Cdd:PRK09528 166 NINPQINFWLGSGSALILLVLLffaKPDAPStAKVANALGANAsaVSLKDalaLLKLPKFWFLVLYVIGV----ACFYDv 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 225 --------FASLF-WKEAGysDLVIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLI 295
Cdd:PRK09528 242 fdqqfpnfFASFFaTPEQG--TRVFGYLNSFQVFLEALIMFFAPFIINRIGAKNALLLAGTIMAVRIIGSGFATGPLEVS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 296 IVQVLHSGTFTVCHLAAMRFISARKENEI---IPLQGAysALATGGGLAVITIMVGYIYERMPDQHgvVFYLMALLAVPA 372
Cdd:PRK09528 320 ILKLLHAFEVPFLLVGVFKYITLNFDVRLsatIYLVGF--QFAKQLGAVFLSTLAGNLYDSIGFQG--TYLILGGIVLLF 395
|
...
gi 493708990 373 LFI 375
Cdd:PRK09528 396 TLI 398
|
|
| MFS_YxlH_like |
cd17490 |
Bacillus subtilis YxlH and similar transporters of the Major Facilitator Superfamily; This ... |
14-375 |
1.23e-04 |
|
Bacillus subtilis YxlH and similar transporters of the Major Facilitator Superfamily; This subfamily is composed of Bacillus subtilis YxlH uncharacterized MFS-type transporter YxlH and similar proteins. The biological function of YxlH remains unclear. The YxlH-like subfamily belongs to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341043 [Multi-domain] Cd Length: 371 Bit Score: 43.75 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 14 FTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLG------------IGLAARFLGamfitpqvKEPSKLINGLRLLAALSL 81
Cdd:cd17490 6 FLFWFSQYVYVPFLSPYAESLGASLSMIGIILGaygisqmllripLGILSDRIG--------KRKLFIIIGLLFTVLASL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 82 IFsigFSFGSHWAWLMFVM---------IGFNLFFAPMVPLGDSLAGTwqkqftfdyGKIRVWGSIAFIIGSSSMGYFAG 152
Cdd:cd17490 78 IM---ILFPSPWGLLIARFlsgiaaatwVSFTVLYASYFPPDEAAKAM---------GLINLVNNLGQLIAFLIGGLIAE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 153 VWGHTSI-MVALVISCAALLFGAMLKPAIMPAGVAKTEGTNkvsFKQLIADKNVLMFLICVTLLQGA-HAAYYGFASLFW 230
Cdd:cd17490 146 HFGMRAPfLLAALAGVLGFILSLFIKEERREKKPVLTELKE---LLSVLKDKKLLFFSLLAILQQMItFSTTFGFTPLIA 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 231 KEAGYSDLVIGNLWSLGVVAEVIVFMLSHRLF-RRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLhSG-----T 304
Cdd:cd17490 223 KQLGASSFQLGLLSIIYLLPNALASLLSGTLFyKKLGERNTIIIGFLLLGAYCFLIPFAPNLTLLYLLQAL-NGfgtgiL 301
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 493708990 305 FTVCHLAAMRFISARKENEIIPLQGAYSALatggGLAVITIMVGYIYERMPDQHGvvFYLMALLAVPALFI 375
Cdd:cd17490 302 FPLLMSLSIEGVPAEQRSTAMGFFQAIYAL----GMFLGPVLVGIISEAFGLQTG--FFVIGVIALLAAIL 366
|
|
| MFS_MFSD6L |
cd17479 |
Major facilitator superfamily domain-containing protein 6-like and similar transporters of the ... |
13-353 |
2.94e-04 |
|
Major facilitator superfamily domain-containing protein 6-like and similar transporters of the Major Facilitator Superfamily; Major facilitator superfamily domain-containing protein 6-like (MFSD6L) protein family includes a group uncharacterized proteins similar to human major facilitator superfamily domain-containing protein 6 (MFSD6). MFSD6 is also called Macrophage MHC class I receptor 2 homolog (MMR2). It has been postulated as a possible receptor for human leukocyte antigen (HLA)-B62. The MFSD6L family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341032 [Multi-domain] Cd Length: 376 Bit Score: 42.68 E-value: 2.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 13 YFTYFFAYSIFLPFWSVWLQGEGIDAEMIGLLLGIGLAARFLGAMFITPQVKEPSKlingLRLLAALSLIFSIGFSFGSH 92
Cdd:cd17479 5 HFFHSAGKACLLPFLTLYFRQLGLTAPQVGIIIGSKHLISLLWAPFWSFLAKSYRK----RRFVILFSLLISLGTYLLYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 93 WAWLM-FVMIGFNLFFAPmvPLGDSLAGTWQK-----QFTFDYGKIRVWGSIAFIIGSSSMGYFAgvwGHTSIMVALVIS 166
Cdd:cd17479 81 QIFLLvLLVIIIWELLSA--PLEKVADDSLYEyldfvDATERYGKLKVWSALGAAFGPCGITLLV---DNLDCFLPPKIS 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 167 --------CAALLFGAMLKPAIMPAGVAK-TEGTNKV--SFKQLIADKNVLMFLICVTLLQGAHAAYYGFasLFW--KEA 233
Cdd:cd17479 156 rillhfytYGGFMILTFLLSFFYPIPVPKkEEHSSKVvkGLRLLGGDGRAILYALTVFLVGFVGSTVQNF--LFWlmQDK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 234 GYSDLVIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLAAM 313
Cdd:cd17479 234 GGSELHMGLSIALALLSEILMSFFGNWLLRKLGHAGCVVLGLLGLGAQLLYYSFLWTPWAVLPIELLHAFSNGALWWAVN 313
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 493708990 314 RF----ISARKENEIiplQGAYSALATGGGLAVITIMVGYIYER 353
Cdd:cd17479 314 SQveflASPGMERSL---QLVLRALYYGIGFALGSFVSGFIYDR 354
|
|
| LacY_symp |
pfam01306 |
LacY proton/sugar symporter; This family is closely related to the sugar transporter family. |
13-318 |
1.37e-03 |
|
LacY proton/sugar symporter; This family is closely related to the sugar transporter family.
Pssm-ID: 396050 Cd Length: 413 Bit Score: 40.52 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 13 YFTYFFAYSIFLPFWSVWLQG-EGIDAEMIGLLLG-IGLAARFLGAMFITPQVKEPSK-----LINGLRLLAALSLIFSI 85
Cdd:pfam01306 16 FFFYFFIMSAYFPFFPIWLHDvNHLSKTDTGIVFScISLFSILFQPLFGLISDKLGLRkhllwCITGLLVLFAPFFIYVF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 86 GFSFGSH-WAWLMFVMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHtsiMVALV 164
Cdd:pfam01306 96 GPLLQSNiLVGAIVGGVYLGFVFSAGAGAIEAYIEKVSRRSNFEYGKARMFGCVGWALCASIAGILFSIDPQ---IVFWL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 165 ISCAALLFGAML---KP-AIMPAGVAKTEGTNKVSFK-----QLIADKNVLMFLICVTLLQGAH----AAYYGFASLFWK 231
Cdd:pfam01306 173 GSGFALILALLLmfaKPdKSSSAIVADALGANKSAFSlrlalELFRMPKFWVFVLYVVGVACVYdvfdQQFANFFTSFFA 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 232 EAGYSDLVIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLA 311
Cdd:pfam01306 253 TPQQGTRVFGYVTTMGELLNALIMFCAPLIINRIGAKNALLIAGTIMSVRILGSSFATTALEVVILKMLHMFEVPFLLVG 332
|
....*..
gi 493708990 312 AMRFISA 318
Cdd:pfam01306 333 CFKYITS 339
|
|
| 2A0105 |
TIGR00882 |
oligosaccharide:H+ symporter; [Transport and binding proteins, Carbohydrates, organic alcohols, ... |
13-318 |
5.49e-03 |
|
oligosaccharide:H+ symporter; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 211613 Cd Length: 396 Bit Score: 38.57 E-value: 5.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 13 YFTYFFAYSIFLPFWSVWLQG-EGIDAEMIGLLLG-IGLAARFLGAMFITPQVKEPSK-----LINGLRLLAALSLIFSI 85
Cdd:TIGR00882 11 FFLYFFIMSAYFPFFPIWLHDvNGLSKTDTGIVFScISLFSILFQPLFGLISDKLGLKkhllwIISGLLVLFAPFFIYVF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 86 GFSFGSH-WAWLMFVMIGFNLFFAPMVPLGDSLAGTWQKQFTFDYGKIRVWGSIAFIIGSSSMGYFAGVWGHtsiMVALV 164
Cdd:TIGR00882 91 GPLLQSNiLVGAIVGGLYLGFVFSAGAGAIEAYIEKVSRNSNFEYGKARMFGCVGWALCASIAGILFSIDPQ---IVFWL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 165 ISCAALLFGAML---------KPAIMPAGVAKTEGTNKVSFKQLIADKNVLMFLICVTLLQGAH----AAYYGFASLFWK 231
Cdd:TIGR00882 168 GSGFALILMLLLmfakpkapsSATVANALGANASAFSLKLALELFRQRKFWMFVLYVVGVACVYdvfdQQFANFFTSFFA 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 493708990 232 EAGYSDLVIGNLWSLGVVAEVIVFMLSHRLFRRWSARNLLLLSAVCGIIRWGMMGAFTALPVLIIVQVLHSGTFTVCHLA 311
Cdd:TIGR00882 248 TPQQGTRVFGYVTTMGELLNALIMFCAPLIINRIGAKNALLIAGTIMSVRIIGSSFATTALEVVILKMLHAFEVPFLLVG 327
|
....*..
gi 493708990 312 AMRFISA 318
Cdd:TIGR00882 328 CFKYITS 334
|
|
| |
