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Conserved domains on  [gi|494020831|ref|WP_006963116|]
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MULTISPECIES: recombination regulator RecX [Vibrio]

Protein Classification

regulatory protein RecX( domain architecture ID 10011252)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
recX PRK00117
recombination regulator RecX; Reviewed
4-152 7.39e-58

recombination regulator RecX; Reviewed


:

Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 177.39  E-value: 7.39e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831   4 RKPPTLSSKEAAIQLLSRRDHGEYELYHKLAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQHVYKGHGERRIRQEL 83
Cdd:PRK00117   6 RRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRARKGYGPRRIRQEL 85
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 494020831  84 NQKRVSESVIEKAFEEEPQDWFELAKQAAEKKFKGVKAKDQKEYAKQVRFLQYRGYSFEQISYALSNED 152
Cdd:PRK00117  86 RQKGVDREIIEEALAELDIDWEELARELARKKFRRPLPDDAKEKAKLVRFLARRGFSMDVIQRVLRNAL 154
 
Name Accession Description Interval E-value
recX PRK00117
recombination regulator RecX; Reviewed
4-152 7.39e-58

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 177.39  E-value: 7.39e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831   4 RKPPTLSSKEAAIQLLSRRDHGEYELYHKLAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQHVYKGHGERRIRQEL 83
Cdd:PRK00117   6 RRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRARKGYGPRRIRQEL 85
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 494020831  84 NQKRVSESVIEKAFEEEPQDWFELAKQAAEKKFKGVKAKDQKEYAKQVRFLQYRGYSFEQISYALSNED 152
Cdd:PRK00117  86 RQKGVDREIIEEALAELDIDWEELARELARKKFRRPLPDDAKEKAKLVRFLARRGFSMDVIQRVLRNAL 154
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
12-152 9.94e-45

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 143.78  E-value: 9.94e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831  12 KEAAIQLLSRRDHGEYELYHKLAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQHVY-KGHGERRIRQELNQKRVSE 90
Cdd:COG2137    9 RNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRrKGYGPRRIRQELRQKGIDE 88
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 494020831  91 SVIEKAFEE-EPQDWFELAKQAAEKKFKGVKAKD-QKEYAKQVRFLQYRGYSFEQISYALSNED 152
Cdd:COG2137   89 ELIEEALEElDEEDELEAARELARKKFGSLKPLDpAKEKQKLARFLARRGFSSDLIRRVLRELL 152
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
33-152 4.95e-30

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 105.36  E-value: 4.95e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831   33 LAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQHV-YKGHGERRIRQELNQKRVSESVIEKAFEEepQDWFEL-AKQ 110
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRArTRGKGPRRIRQELRQKGVDEEIIEEALEE--FDEEEQiARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 494020831  111 AAEKKFKGVKAK-DQKEYAKQVRFLQYRGYSFEQISYALSNED 152
Cdd:pfam02631  79 LAEKKFKRYPAEsDRKLKQKLIRFLARRGFSSEVIRAALQEED 121
 
Name Accession Description Interval E-value
recX PRK00117
recombination regulator RecX; Reviewed
4-152 7.39e-58

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 177.39  E-value: 7.39e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831   4 RKPPTLSSKEAAIQLLSRRDHGEYELYHKLAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQHVYKGHGERRIRQEL 83
Cdd:PRK00117   6 RRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRARKGYGPRRIRQEL 85
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 494020831  84 NQKRVSESVIEKAFEEEPQDWFELAKQAAEKKFKGVKAKDQKEYAKQVRFLQYRGYSFEQISYALSNED 152
Cdd:PRK00117  86 RQKGVDREIIEEALAELDIDWEELARELARKKFRRPLPDDAKEKAKLVRFLARRGFSMDVIQRVLRNAL 154
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
12-152 9.94e-45

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 143.78  E-value: 9.94e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831  12 KEAAIQLLSRRDHGEYELYHKLAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQHVY-KGHGERRIRQELNQKRVSE 90
Cdd:COG2137    9 RNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRrKGYGPRRIRQELRQKGIDE 88
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 494020831  91 SVIEKAFEE-EPQDWFELAKQAAEKKFKGVKAKD-QKEYAKQVRFLQYRGYSFEQISYALSNED 152
Cdd:COG2137   89 ELIEEALEElDEEDELEAARELARKKFGSLKPLDpAKEKQKLARFLARRGFSSDLIRRVLRELL 152
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
33-152 4.95e-30

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 105.36  E-value: 4.95e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831   33 LAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQHV-YKGHGERRIRQELNQKRVSESVIEKAFEEepQDWFEL-AKQ 110
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRArTRGKGPRRIRQELRQKGVDEEIIEEALEE--FDEEEQiARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 494020831  111 AAEKKFKGVKAK-DQKEYAKQVRFLQYRGYSFEQISYALSNED 152
Cdd:pfam02631  79 LAEKKFKRYPAEsDRKLKQKLIRFLARRGFSSEVIRAALQEED 121
recX PRK14135
recombination regulator RecX; Provisional
15-152 2.89e-16

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 72.94  E-value: 2.89e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831  15 AIQLLSRRDHGEYELYHKLAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQHVYKG-HGERRIRQELNQKRVSESVI 93
Cdd:PRK14135  63 ALYYLSYQMRTEKEVRDYLKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGdKGPRVIKQKLLQKGIEDEII 142
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 494020831  94 EKAFEE-EPQDWFELAKQAAEKKFKGVKAKDQKEYAKQVR-FLQYRGYSFEQISYALSNED 152
Cdd:PRK14135 143 EEALSEyTEEDQIEVAQKLAEKLLKKYQKLPFKALKQKIIqSLLTKGFSYEVIKAALEELD 203
recX PRK14134
recombination regulator RecX; Provisional
9-148 9.60e-14

recombination regulator RecX; Provisional


Pssm-ID: 184530 [Multi-domain]  Cd Length: 283  Bit Score: 66.37  E-value: 9.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831   9 LSSKEAAIQLLSRRDHGEYELYHKLAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQHVYKgHGERRIRQELNQKRV 88
Cdd:PRK14134  61 IKCKGYALKYIEKSYKTEKQIKEKLYLKEYDEDAVNRVIRFLKEYNFIDDDKYCDMYIREKINS-YGRNKIKYTLLNKGI 139
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831  89 SESVIEK-------AFEEepqdwfELAKQAAEKKFKGVKAKD---QKEYAKQVRFLQYRGYSFEQISYAL 148
Cdd:PRK14134 140 KENIIIEkinnideEKEK------KVAYKLAEKKYKILILSEknkFKIYKKLGPYLISRGYSSNIAEWIL 203
recX PRK14136
recombination regulator RecX; Provisional
5-152 3.60e-13

recombination regulator RecX; Provisional


Pssm-ID: 237620 [Multi-domain]  Cd Length: 309  Bit Score: 65.02  E-value: 3.60e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831   5 KPPTlSSKEAAIQLLSRRDHGEYELYHKLAMKGYEEEAIqEAVNFCLEH-NYLDDLRYTKSQIRQHVYKgHGERRIRQEL 83
Cdd:PRK14136 159 RPAR-SLKGRALGYLSRREYSRAELARKLAPYADESDSV-EPLLDALEReGWLSDARFAESLVHRRASR-VGSARIVSEL 235
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 494020831  84 NQKRVSESVIEKAFEEEPQDWFELAKQAAEKKFkGVKAKDQKEYAKQVRFLQYRGYSFEQISYALSNED 152
Cdd:PRK14136 236 KRHAVGDALVESVGAQLRETEFERAQAVWRKKF-GALPQTPAERAKQARFLAARGFSSATIVKLLKVGD 303
recX PRK14137
recombination regulator RecX; Provisional
3-140 2.08e-03

recombination regulator RecX; Provisional


Pssm-ID: 172626  Cd Length: 195  Bit Score: 36.88  E-value: 2.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494020831   3 QRKPPTL-SSKEA----AIQLLSRRDHGEYELYHKLAMKGYEEEAIQEAVNFCLEHNYLDDLRYTKSQIRQhvyKGHGER 77
Cdd:PRK14137  29 RRTPPTPdEAREAllayAFRALAARAMTAAELRAKLERRSEDEALVTEVLERVQELGYQDDAQVARAENSR---RGVGAL 105
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 494020831  78 RIRQELNQKRVSESVIEKAFE-EEPQDWFELAKQAAEKKFKGVkAKDQKEYAKQVRFLQYRGYS 140
Cdd:PRK14137 106 RVRQTLRRRGVEETLIEETLAaRDPQEEQQEARNLLERRWSSF-ARKRDPRASAYAFLARRGFS 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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