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Conserved domains on  [gi|494040105|ref|WP_006982230|]
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phosphopyruvate hydratase [Chthoniobacter flavus]

Protein Classification

phosphopyruvate hydratase( domain architecture ID 11414960)

phosphopyruvate hydratase (enolase) catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways

CATH:  3.20.20.120|3.30.390.10
EC:  4.2.1.11
Gene Ontology:  GO:0004634|GO:0000015|GO:0006096|GO:0000287
PubMed:  8994873|8605183
SCOP:  3001064|3000476

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 2-422 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 678.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   2 KISSISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRGR 81
Cdd:COG0148    3 RIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIGM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  82 DVFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLG--TGDLLPLPEIQITGGGAHANWRTDV 159
Cdd:COG0148   83 DATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGgvNAKTLPVPMMNIINGGAHADNNVDI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 160 QDYLLIATGARSYAEVMEITHNVYHAAGDILKRRGSYFGVADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGRDAVISLD 239
Cdd:COG0148  163 QEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALALD 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 240 VAASDLFDEesGTYQFGLEQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMVFQKLGRKIQLIGDDLFTTNIH 319
Cdd:COG0148  243 VAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 320 RIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQLKVGSFSRSERMAK 399
Cdd:COG0148  321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400

                        410       420
                 ....*....|....*....|...
gi 494040105 400 WNEVIRIERALGERARFVGSQIF 422
Cdd:COG0148  401 YNQLLRIEEELGDAARYAGRSAF 423
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 2-422 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 678.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   2 KISSISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRGR 81
Cdd:COG0148    3 RIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIGM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  82 DVFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLG--TGDLLPLPEIQITGGGAHANWRTDV 159
Cdd:COG0148   83 DATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGgvNAKTLPVPMMNIINGGAHADNNVDI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 160 QDYLLIATGARSYAEVMEITHNVYHAAGDILKRRGSYFGVADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGRDAVISLD 239
Cdd:COG0148  163 QEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALALD 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 240 VAASDLFDEesGTYQFGLEQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMVFQKLGRKIQLIGDDLFTTNIH 319
Cdd:COG0148  243 VAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 320 RIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQLKVGSFSRSERMAK 399
Cdd:COG0148  321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400

                        410       420
                 ....*....|....*....|...
gi 494040105 400 WNEVIRIERALGERARFVGSQIF 422
Cdd:COG0148  401 YNQLLRIEEELGDAARYAGRSAF 423
eno PRK00077
enolase; Provisional
 1-422 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 620.95  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   1 MKISSISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRG 80
Cdd:PRK00077   2 SKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  81 RDVFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLG--TGDLLPLPEIQITGGGAHANWRTD 158
Cdd:PRK00077  82 LDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGgpNAKVLPVPMMNIINGGAHADNNVD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 159 VQDYLLIATGARSYAEVMEITHNVYHAAGDILKRRGSYFGVADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGRDAVISL 238
Cdd:PRK00077 162 IQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALAL 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 239 DVAASDLFdeESGTYQFglEQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMVFQKLGRKIQLIGDDLFTTNI 318
Cdd:PRK00077 242 DCAASEFY--KDGKYVL--EGEGLTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNT 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 319 HRIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQLKVGSFSRSERMA 398
Cdd:PRK00077 318 KRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIA 397

                        410       420
                 ....*....|....*....|....
gi 494040105 399 KWNEVIRIERALGERARFVGSQIF 422
Cdd:PRK00077 398 KYNQLLRIEEELGDAARYAGKKAF 421
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 5-407 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 583.29  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   5 SISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRGRDVF 84
Cdd:cd03313    1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  85 DQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLG--TGDLLPLPEIQITGGGAHANWRTDVQDY 162
Cdd:cd03313   81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGglAAYVLPVPMFNVINGGAHAGNKLDFQEF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 163 LLIATGARSYAEVMEITHNVYHAAGDILKRRGSYF--GVADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGRDAVISLDV 240
Cdd:cd03313  161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGGLLatNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 241 AASDLFDEESGTYQfGLEQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMVFQKLGRKIQLIGDDLFTTNIHR 320
Cdd:cd03313  241 AASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 321 IRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQLKVGSFSRSERMAKW 400
Cdd:cd03313  320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399


                 ....*..
gi 494040105 401 NEVIRIE 407
Cdd:cd03313  400 NQLLRIE 406
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 3-425 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 553.89  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105    3 ISSISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRGRD 82
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   83 VFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLG--TGDLLPLPEIQITGGGAHANWRTDVQ 160
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGgfNAYVLPVPMMNIINGGAHADNNLDFQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  161 DYLLIATGARSYAEVMEITHNVYHAAGDILKRRGSYFGVADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGRDAVISLDV 240
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  241 AASDLFDEESGTYQFGLEQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMVFQKLGRKIQLIGDDLFTTNIHR 320
Cdd:TIGR01060 241 AASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  321 IRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQLKVGSFSRSERMAKW 400
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400

                         410       420
                  ....*....|....*....|....*
gi 494040105  401 NEVIRIERALGERARFVGSQIFETI 425
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
139-418 3.73e-109

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 323.66  E-value: 3.73e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  139 LPLPEIQITGGGAHANWRTDVQDYLLIATGARSYAEVMEITHNVYHAAGDILKRRG--SYFGVADEGGYWPEFKTNEEPL 216
Cdd:pfam00113   4 LPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKEAL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  217 QLLVEAIKAAGYEPgrDAVISLDVAASDLFDEESGTYQFGLE------QRRFSTAEFAALIEDWCARYPIISLEDPMADT 290
Cdd:pfam00113  84 DLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKgeksdkSKKLTSAQLADLYEELVKKYPIVSIEDPFDED 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  291 DWEGWQMVFQKLGRKIQLIGDDLFTTNIHRIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETE 370
Cdd:pfam00113 162 DWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETE 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 494040105  371 DTFISHLAVAANAGQLKVGSFSRSERMAKWNEVIRIERALGERARFVG 418
Cdd:pfam00113 242 DTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAG 289
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 2-422 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 678.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   2 KISSISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRGR 81
Cdd:COG0148    3 RIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIGM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  82 DVFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLG--TGDLLPLPEIQITGGGAHANWRTDV 159
Cdd:COG0148   83 DATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGgvNAKTLPVPMMNIINGGAHADNNVDI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 160 QDYLLIATGARSYAEVMEITHNVYHAAGDILKRRGSYFGVADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGRDAVISLD 239
Cdd:COG0148  163 QEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALALD 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 240 VAASDLFDEesGTYQFGLEQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMVFQKLGRKIQLIGDDLFTTNIH 319
Cdd:COG0148  243 VAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 320 RIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQLKVGSFSRSERMAK 399
Cdd:COG0148  321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400

                        410       420
                 ....*....|....*....|...
gi 494040105 400 WNEVIRIERALGERARFVGSQIF 422
Cdd:COG0148  401 YNQLLRIEEELGDAARYAGRSAF 423
eno PRK00077
enolase; Provisional
 1-422 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 620.95  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   1 MKISSISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRG 80
Cdd:PRK00077   2 SKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  81 RDVFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLG--TGDLLPLPEIQITGGGAHANWRTD 158
Cdd:PRK00077  82 LDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGgpNAKVLPVPMMNIINGGAHADNNVD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 159 VQDYLLIATGARSYAEVMEITHNVYHAAGDILKRRGSYFGVADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGRDAVISL 238
Cdd:PRK00077 162 IQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALAL 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 239 DVAASDLFdeESGTYQFglEQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMVFQKLGRKIQLIGDDLFTTNI 318
Cdd:PRK00077 242 DCAASEFY--KDGKYVL--EGEGLTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNT 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 319 HRIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQLKVGSFSRSERMA 398
Cdd:PRK00077 318 KRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIA 397

                        410       420
                 ....*....|....*....|....
gi 494040105 399 KWNEVIRIERALGERARFVGSQIF 422
Cdd:PRK00077 398 KYNQLLRIEEELGDAARYAGKKAF 421
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 5-407 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 583.29  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   5 SISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRGRDVF 84
Cdd:cd03313    1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  85 DQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLG--TGDLLPLPEIQITGGGAHANWRTDVQDY 162
Cdd:cd03313   81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGglAAYVLPVPMFNVINGGAHAGNKLDFQEF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 163 LLIATGARSYAEVMEITHNVYHAAGDILKRRGSYF--GVADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGRDAVISLDV 240
Cdd:cd03313  161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGGLLatNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 241 AASDLFDEESGTYQfGLEQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMVFQKLGRKIQLIGDDLFTTNIHR 320
Cdd:cd03313  241 AASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 321 IRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQLKVGSFSRSERMAKW 400
Cdd:cd03313  320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399


                 ....*..
gi 494040105 401 NEVIRIE 407
Cdd:cd03313  400 NQLLRIE 406
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 3-425 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 553.89  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105    3 ISSISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRGRD 82
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   83 VFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLG--TGDLLPLPEIQITGGGAHANWRTDVQ 160
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGgfNAYVLPVPMMNIINGGAHADNNLDFQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  161 DYLLIATGARSYAEVMEITHNVYHAAGDILKRRGSYFGVADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGRDAVISLDV 240
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  241 AASDLFDEESGTYQFGLEQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMVFQKLGRKIQLIGDDLFTTNIHR 320
Cdd:TIGR01060 241 AASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  321 IRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQLKVGSFSRSERMAKW 400
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400

                         410       420
                  ....*....|....*....|....*
gi 494040105  401 NEVIRIERALGERARFVGSQIFETI 425
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
PTZ00081 PTZ00081
enolase; Provisional
 1-419 2.37e-158

enolase; Provisional


Pssm-ID: 240259 [Multi-domain]  Cd Length: 439  Bit Score: 454.51  E-value: 2.37e-158
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   1 MKISSISAYQVFDSRGNPTVEAEVVLENGVRgRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRG 80
Cdd:PTZ00081   2 STIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALIG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  81 RDVFDQAGLDQAMIE-LDGTPN-----KSRLGANAILGVSMAATAAAASARGEPLFAYL----GTGD---LLPLPEIQIT 147
Cdd:PTZ00081  81 KDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLaqlaGKPTdkfVLPVPCFNVI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 148 GGGAHANWRTDVQDYLLIATGARSYAEVMEITHNVYHAAGDILKRRgsyFG-----VADEGGYWPEFKTNEEPLQLLVEA 222
Cdd:PTZ00081 161 NGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKK---YGldatnVGDEGGFAPNIKDPEEALDLLVEA 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 223 IKAAGYEpGRDAvISLDVAASDLFDEESGTYQFGL------EQRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQ 296
Cdd:PTZ00081 238 IKKAGYE-GKVK-ICMDVAASEFYDKEKKVYDLDFknpnndKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYA 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 297 MVFQKLGRKIQLIGDDLFTTNIHRIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISH 376
Cdd:PTZ00081 316 KLTAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIAD 395

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|...
gi 494040105 377 LAVAANAGQLKVGSFSRSERMAKWNEVIRIERALGERARFVGS 419
Cdd:PTZ00081 396 LVVGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAGE 438
PLN00191 PLN00191
enolase
 2-418 8.77e-143

enolase


Pssm-ID: 215095 [Multi-domain]  Cd Length: 457  Bit Score: 415.26  E-value: 8.77e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105   2 KISSISAYQVFDSRGNPTVEAEVVLENGVRgRGTVPSGASTGQFEALELRDRDvQCFRGKSVLRAIANVQDIIRRELRGR 81
Cdd:PLN00191  27 TITKVKARQIIDSRGNPTVEVDLHTSKGMF-RAAVPSGASTGIYEALELRDGD-KDYLGKGVLKAVKNVNEIIAPALIGM 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  82 DVFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYL----GTGDL-LPLPEIQITGGGAHANWR 156
Cdd:PLN00191 105 DPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHIadlaGNKKLvLPVPAFNVINGGSHAGNK 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 157 TDVQDYLLIATGARSYAEVMEITHNVYHAAGDILKRRgsyFG-----VADEGGYWPEFKTNEEPLQLLVEAIKAAGYEpG 231
Cdd:PLN00191 185 LAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKK---YGqdacnVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT-G 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 232 RdAVISLDVAASDlFDEESGTYQFGLE------QRRFSTAEFAALIEDWCARYPIISLEDPMADTDWEGWQMvFQKLGrK 305
Cdd:PLN00191 261 K-IKIGMDVAASE-FYTKDKKYDLDFKeenndgSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAK-LTSLE-D 336

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 306 IQLIGDDLFTTNIHRIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHLAVAANAGQ 385
Cdd:PLN00191 337 VQIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQ 416

                        410       420       430
                 ....*....|....*....|....*....|...
gi 494040105 386 LKVGSFSRSERMAKWNEVIRIERALGERARFVG 418
Cdd:PLN00191 417 IKTGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
139-418 3.73e-109

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 323.66  E-value: 3.73e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  139 LPLPEIQITGGGAHANWRTDVQDYLLIATGARSYAEVMEITHNVYHAAGDILKRRG--SYFGVADEGGYWPEFKTNEEPL 216
Cdd:pfam00113   4 LPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKEAL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  217 QLLVEAIKAAGYEPgrDAVISLDVAASDLFDEESGTYQFGLE------QRRFSTAEFAALIEDWCARYPIISLEDPMADT 290
Cdd:pfam00113  84 DLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKgeksdkSKKLTSAQLADLYEELVKKYPIVSIEDPFDED 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  291 DWEGWQMVFQKLGRKIQLIGDDLFTTNIHRIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETE 370
Cdd:pfam00113 162 DWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETE 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 494040105  371 DTFISHLAVAANAGQLKVGSFSRSERMAKWNEVIRIERALGERARFVG 418
Cdd:pfam00113 242 DTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAG 289
Enolase_N pfam03952
Enolase, N-terminal domain;
3-133 7.96e-66

Enolase, N-terminal domain;


Pssm-ID: 461105 [Multi-domain]  Cd Length: 131  Bit Score: 206.46  E-value: 7.96e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105    3 ISSISAYQVFDSRGNPTVEAEVVLENGVRGRGTVPSGASTGQFEALELRDRDVQCFRGKSVLRAIANVQDIIRRELRGRD 82
Cdd:pfam03952   1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 494040105   83 VFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYL 133
Cdd:pfam03952  81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
PRK08350 PRK08350
hypothetical protein; Provisional
 65-417 5.20e-14

hypothetical protein; Provisional


Pssm-ID: 169397 [Multi-domain]  Cd Length: 341  Bit Score: 72.92  E-value: 5.20e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  65 RAIANVQDIIRRELRGRDVFDQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYLGtGDL---LPL 141
Cdd:PRK08350  51 RAVSEVDEIIGPELIGFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIG-GTFtteLPV 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 142 PEIQITGGgahanwrtDVQDYLLIATgarsyaEVMEIThNVYHAAGDILKrrgsyfgvadeggywpefKTNEEPLQLLVE 221
Cdd:PRK08350 130 PILEFAED--------ENFEYYVLVR------DLMEIT-DVVDAVNKILE------------------NSKEVSLEGLSK 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 222 AIKAAGYEPGrdavisLDVAasdlfdeesgtyqFGLEQRR-FSTAEFAALIEDWCARYPiisleDPMADTDwegwqmVFQ 300
Cdd:PRK08350 177 ASEKAGDELG------LEVA-------------LGIAQKReMETEKVLNLVEDNNIAYI-----KPIGDEE------LFL 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 301 KL---GRKIQLIGDDLFttnihRIRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSGETEDTFISHL 377
Cdd:PRK08350 227 ELiagTHGVFIDGEYLF-----RTRNILDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHL 301

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 494040105 378 AVAANAGQLKVGSFSrserMAKWNEVIRIERALGERARFV 417
Cdd:PRK08350 302 AVGLRCPAMLIHKDS----VEKINELNRIAEDLGERGRII 337
enolase_like cd00308
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ...
 212-382 8.08e-12

Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.


Pssm-ID: 238188 [Multi-domain]  Cd Length: 229  Bit Score: 64.66  E-value: 8.08e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 212 NEEPLQLLVEAIkaagyepGRDAVISLDVAasdlfdeesgtyqfgleqRRFSTAEFAALIEDwCARYPIISLEDPMADTD 291
Cdd:cd00308   80 SIERVRAVREAF-------GPDARLAVDAN------------------GAWTPKEAIRLIRA-LEKYGLAWIEEPCAPDD 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 292 WEGWQMVFQKLGrkIQLIGDDLFTTNIHRIRtGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQAGWLPVVSARSG-ETE 370
Cdd:cd00308  134 LEGYAALRRRTG--IPIAADESVTTVDDALE-ALELGAVDILQIKPTRVGGLTESRRAADLAEAFGIRVMVHGTLEsSIG 210

                        170
                 ....*....|..
gi 494040105 371 DTFISHLAVAAN 382
Cdd:cd00308  211 TAAALHLAAALP 222
PTZ00378 PTZ00378
hypothetical protein; Provisional
 85-389 1.89e-04

hypothetical protein; Provisional


Pssm-ID: 173571 [Multi-domain]  Cd Length: 518  Bit Score: 43.71  E-value: 1.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105  85 DQAGLDQAMIELDGTPNKSRLGANAILGVSMAATAAAASARGEPLFAYL-------GTGDLLPLPEIQIT--GGGAHANW 155
Cdd:PTZ00378 126 DQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLralfgslTSVETFSMPQLCITffGPGNPSTA 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 156 RTDVQDYLLI---ATGARSYaevmEITHNVYHAAGDILKRRGSYFGvADEGGYWPEFKTNEEPLQLLVEAIKAAGYEPGR 232
Cdd:PTZ00378 206 RLALKSVLFSpvmPSGTVLR----ERMQKIFAAFHHFCQSHNSSVR-SDGSLHWDGFANLTDAVKLATEALRAVQLTPGT 280

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 233 DAVISLDVAASDLFDEESGTYQFGLEQRRFSTAE-FAALIE-------DWCARYP----------IISLEDPMADTDWEG 294
Cdd:PTZ00378 281 DVCLGLRMAASTTRVPATAVADGGAWKEAKDDCEvLYSLFPgepdvtgDQLSEYVreqlqavpdiVVYVEDTHCDEDTFG 360

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 295 WQMVFQKLGRKIQLIGDDLFTTNIHR-IRTGIEKGIANAVLIKLNQIGTVTETLEAIRTTQQ-AGWLPVVSARSGETEDT 372
Cdd:PTZ00378 361 LQRLQAALGDSIVLSGVDVYARSEYKkVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGEdEGRAVTVLVQTLAGNAA 440

                        330
                 ....*....|....*..
gi 494040105 373 FISHLAVAANAGQLKVG 389
Cdd:PTZ00378 441 TAAHLAVAMGARFLCSG 457
RspA COG4948
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ...
 261-383 2.35e-03

L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 443975 [Multi-domain]  Cd Length: 359  Bit Score: 39.81  E-value: 2.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494040105 261 RFSTAEFAALIEdWCARYPIISLEDPMADTDWEGWQMVFQKLGrkIQLIGDDLFTTnIHRIRTGIEKGIANAVLIKLNQI 340
Cdd:COG4948  192 AWTLEEAIRLLR-ALEDLGLEWIEQPLPAEDLEGLAELRRATP--VPIAADESLTS-RADFRRLIEAGAVDIVNIKLSKV 267

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 494040105 341 GTVTETLEAIRTTQQAGwLPVVSarsgetEDTFISHLAVAANA 383
Cdd:COG4948  268 GGLTEALRIAALAEAHG-VPVMP------HCMLESGIGLAAAL 303
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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