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Conserved domains on  [gi|494269470|ref|WP_007155748|]
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enoyl-CoA hydratase/isomerase family protein [Marinobacter algicola]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10787157)

enoyl-CoA hydratase/isomerase family protein similar to human ethylmalonyl-CoA decarboxylase that decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA

CATH:  3.90.226.10
Gene Ontology:  GO:0016829
PubMed:  12467702|22016388

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
10-265 5.41e-73

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 223.51  E-value: 5.41e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAgargqksAEGEEDP 89
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELA-------AAADPEE 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 FYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAP-FVVERIGLTQA 168
Cdd:COG1024   74 ARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTqRLPRLVGLARA 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 169 RRLALLGLRVDADEACRLGIVHQVAESeveiDELLGHAVERVRQCA---PNATAQTKALLHRVGHESMSGLLDSAAAKFA 245
Cdd:COG1024  154 KELLLTGRRIDAEEALELGLVNRVVPD----DELLAAALALAARLAagpPLALAATKRALNAALEAPLDEALELEAEAFA 229
                        250       260
                 ....*....|....*....|
gi 494269470 246 EAIRSDEGSEGTLAFMQKRP 265
Cdd:COG1024  230 ELFASEDAREGIAAFLEKRK 249
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
10-265 5.41e-73

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 223.51  E-value: 5.41e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAgargqksAEGEEDP 89
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELA-------AAADPEE 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 FYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAP-FVVERIGLTQA 168
Cdd:COG1024   74 ARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTqRLPRLVGLARA 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 169 RRLALLGLRVDADEACRLGIVHQVAESeveiDELLGHAVERVRQCA---PNATAQTKALLHRVGHESMSGLLDSAAAKFA 245
Cdd:COG1024  154 KELLLTGRRIDAEEALELGLVNRVVPD----DELLAAALALAARLAagpPLALAATKRALNAALEAPLDEALELEAEAFA 229
                        250       260
                 ....*....|....*....|
gi 494269470 246 EAIRSDEGSEGTLAFMQKRP 265
Cdd:COG1024  230 ELFASEDAREGIAAFLEKRK 249
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
8-268 2.94e-69

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 214.79  E-value: 2.94e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEE 87
Cdd:PRK05995   4 ETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMKKMAGYSDDENRA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 DPfyrlnRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGLTQ 167
Cdd:PRK05995  84 DA-----RRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRAMGERA 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 168 ARRLALLGLRVDADEACRLGIVHQVAESEvEIDELLGHAVERVRQCAPNATAQTKALLHRV-GHESMSGLLDSAAAKFAE 246
Cdd:PRK05995 159 ARRYFLTAERFDAAEALRLGLVHEVVPAE-ALDAKVDELLAALVANSPQAVRAGKRLVRDVaGRPIDAALIADTASRIAL 237
                        250       260
                 ....*....|....*....|..
gi 494269470 247 AIRSDEGSEGTLAFMQKRPASW 268
Cdd:PRK05995 238 IRATEEAREGVAAFLEKRKPAW 259
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
10-212 8.17e-61

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 190.85  E-value: 8.17e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARgqksaeGEEDP 89
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALS------DAGEE 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 FYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-AQIAPFVVERIGLTQA 168
Cdd:cd06558   75 ARAFIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPgGGGTQRLPRLVGPARA 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 494269470 169 RRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQ 212
Cdd:cd06558  155 RELLLTGRRISAEEALELGLVDEV----VPDEELLAAALELARR 194
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
13-268 1.65e-47

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 158.68  E-value: 1.65e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   13 EKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEEdPFYR 92
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRE-NVLD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   93 LNRAfgqmIQQVNessKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-AQIAPFVVERIGLTQARRL 171
Cdd:pfam00378  80 LWTL----LYTCP---KPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPgAGGTDRLPRIIGHSKAMEM 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  172 ALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA---PNATAQTKALLHRVGHESMSGLLDSAAAKFAEAI 248
Cdd:pfam00378 153 LLLGRRISAQEALKWGLVDKV----VPEDQLLDEARELAEKLAeksPAALAQLKKALNAKLEDALPTQLEAEARLFYSTF 228
                         250       260
                  ....*....|....*....|
gi 494269470  249 RSDEGSEGTLAFMQKRPASW 268
Cdd:pfam00378 229 SKDDIIEGLQAFLEKRKPPW 248
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
13-194 5.76e-19

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 86.43  E-value: 5.76e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   13 EKQGPALFVTINRPDVR-NAMSLQMVAELSTVFSQVENDASIR-AVVIRGADGHFCAGGDIKDMAgargqksAEGEEDPF 90
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKsAVLISGKPGSFVAGADIQMIA-------ACKTAQEV 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   91 YRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGF--GLACVSDVAIAGPTAKFGMPETTLGVIPA----QIAPFVVeriG 164
Cdd:TIGR02441  91 TQLSQEGQEMFERIEKSQKPIVAAISGSCLGGGLelALACHYRIATKDRKTLLGLPEVMLGLLPGaggtQRLPKLT---G 167
                         170       180       190
                  ....*....|....*....|....*....|
gi 494269470  165 LTQARRLALLGLRVDADEACRLGIVHQVAE 194
Cdd:TIGR02441 168 VPAALDMMLTGKKIRADRAKKMGIVDQLVD 197
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
10-265 5.41e-73

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 223.51  E-value: 5.41e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAgargqksAEGEEDP 89
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELA-------AAADPEE 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 FYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAP-FVVERIGLTQA 168
Cdd:COG1024   74 ARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTqRLPRLVGLARA 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 169 RRLALLGLRVDADEACRLGIVHQVAESeveiDELLGHAVERVRQCA---PNATAQTKALLHRVGHESMSGLLDSAAAKFA 245
Cdd:COG1024  154 KELLLTGRRIDAEEALELGLVNRVVPD----DELLAAALALAARLAagpPLALAATKRALNAALEAPLDEALELEAEAFA 229
                        250       260
                 ....*....|....*....|
gi 494269470 246 EAIRSDEGSEGTLAFMQKRP 265
Cdd:COG1024  230 ELFASEDAREGIAAFLEKRK 249
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
8-268 2.94e-69

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 214.79  E-value: 2.94e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEE 87
Cdd:PRK05995   4 ETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMKKMAGYSDDENRA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 DPfyrlnRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGLTQ 167
Cdd:PRK05995  84 DA-----RRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRAMGERA 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 168 ARRLALLGLRVDADEACRLGIVHQVAESEvEIDELLGHAVERVRQCAPNATAQTKALLHRV-GHESMSGLLDSAAAKFAE 246
Cdd:PRK05995 159 ARRYFLTAERFDAAEALRLGLVHEVVPAE-ALDAKVDELLAALVANSPQAVRAGKRLVRDVaGRPIDAALIADTASRIAL 237
                        250       260
                 ....*....|....*....|..
gi 494269470 247 AIRSDEGSEGTLAFMQKRPASW 268
Cdd:PRK05995 238 IRATEEAREGVAAFLEKRKPAW 259
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
10-212 8.17e-61

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 190.85  E-value: 8.17e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARgqksaeGEEDP 89
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALS------DAGEE 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 FYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-AQIAPFVVERIGLTQA 168
Cdd:cd06558   75 ARAFIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPgGGGTQRLPRLVGPARA 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 494269470 169 RRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQ 212
Cdd:cd06558  155 RELLLTGRRISAEEALELGLVDEV----VPDEELLAAALELARR 194
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
21-269 2.67e-59

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 189.12  E-value: 2.67e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMagaRGQKSAEGEEDpfYRLNRAFGQM 100
Cdd:PRK07468  18 LTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGWM---RAQMTADRATR--IEEARRLAMM 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 101 IQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGLTQARRLALLGLRVDA 180
Cdd:PRK07468  93 LKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARRVFMSARLFDA 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 181 DEACRLGIVHQVAESEvEIDELLGHAVERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAKFAEAIRSDEGSEGTLAF 260
Cdd:PRK07468 173 EEAVRLGLLSRVVPAE-RLDAAVEAEVTPYLSCAPGAVAAAKALVRALGAPIDEAVIDATIEALADTWETEEAREGIAAF 251

                 ....*....
gi 494269470 261 MQKRPASWA 269
Cdd:PRK07468 252 FDKRAPAWR 260
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
10-266 2.97e-48

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 160.80  E-value: 2.97e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEgeedp 89
Cdd:PRK06688   7 LLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPKAPPKPPDE----- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 fyrlNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-AQIAPFVVERIGLTQA 168
Cdd:PRK06688  82 ----LAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPdAGGSALLPRLIGRARA 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 169 RRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA---PNATAQTKALLHRVGHESMSGLLDSAAAKFA 245
Cdd:PRK06688 158 AEMLLLGEPLSAEEALRIGLVNRV----VPAAELDAEADAQAAKLAagpASALRYTKRAINAATLTELEEALAREAAGFG 233
                        250       260
                 ....*....|....*....|.
gi 494269470 246 EAIRSDEGSEGTLAFMQKRPA 266
Cdd:PRK06688 234 RLLRTPDFREGATAFIEKRKP 254
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
13-268 1.65e-47

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 158.68  E-value: 1.65e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   13 EKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEEdPFYR 92
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRE-NVLD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   93 LNRAfgqmIQQVNessKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-AQIAPFVVERIGLTQARRL 171
Cdd:pfam00378  80 LWTL----LYTCP---KPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPgAGGTDRLPRIIGHSKAMEM 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  172 ALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA---PNATAQTKALLHRVGHESMSGLLDSAAAKFAEAI 248
Cdd:pfam00378 153 LLLGRRISAQEALKWGLVDKV----VPEDQLLDEARELAEKLAeksPAALAQLKKALNAKLEDALPTQLEAEARLFYSTF 228
                         250       260
                  ....*....|....*....|
gi 494269470  249 RSDEGSEGTLAFMQKRPASW 268
Cdd:pfam00378 229 SKDDIIEGLQAFLEKRKPPW 248
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
8-270 2.05e-42

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 145.52  E-value: 2.05e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEE 87
Cdd:PRK07511   3 AELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGNLNRLLENRAKPPSVQAA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 dpfyrLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-----AQIAPFVVER 162
Cdd:PRK07511  83 -----SIDGLHDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPdgggsWFLARALPRQ 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 163 IgltqARRLALLGLRVDADEACRLGIVHQVAESEVEIDELLGHAvERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAA 242
Cdd:PRK07511 158 L----ATELLLEGKPISAERLHALGVVNRLAEPGQALAEALALA-DQLAAGSPNALARIKSLIADAPEATLAAQLEAERD 232
                        250       260
                 ....*....|....*....|....*...
gi 494269470 243 KFAEAIRSDEGSEGTLAFMQKRPASWAA 270
Cdd:PRK07511 233 HFVASLHHADALEGIAAFLEKRAPDYKR 260
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
13-269 3.15e-42

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 145.21  E-value: 3.15e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  13 EKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGargqkSAEGEEDPFYR 92
Cdd:PRK07827  11 AVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAGG-----GGGDPYDAAVA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  93 LNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGLTQARRLA 172
Cdd:PRK07827  86 RAREMTALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYY 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 173 LLGLRVDADEACRLGIVHQVAEsevEIDELLGHAVERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAKFAEAIRSDE 252
Cdd:PRK07827 166 LTGEKFGAAEAARIGLVTAAAD---DVDAAVAALLADLRRGSPQGLAESKALTTAAVLAGFDRDAEELTEESARLFVSDE 242
                        250
                 ....*....|....*..
gi 494269470 253 GSEGTLAFMQKRPASWA 269
Cdd:PRK07827 243 AREGMTAFLQKRPPRWA 259
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
9-268 1.44e-40

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 141.10  E-value: 1.44e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   9 TLLLEKQgPALFVTI--NRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMagargQKSAEGE 86
Cdd:PRK05674   6 TIELIRD-PRGFATLwlSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLAWM-----QQSADLD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  87 EDPFYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGLT 166
Cdd:PRK05674  80 YNTNLDDARELAELMYNLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGER 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 167 QARRLALLGLRVDADEACRLGIVHQVAESeVEIDELLGHAVERVRQCAPNATAQTKALLHRVGhesmSGLLDSAAAKFAE 246
Cdd:PRK05674 160 AARRYALTAERFDGRRARELGLLAESYPA-AELEAQVEAWIANLLLNSPQALRASKDLLREVG----DGELSPALRRYCE 234
                        250       260
                 ....*....|....*....|....*..
gi 494269470 247 A----IR-SDEGSEGTLAFMQKRPASW 268
Cdd:PRK05674 235 NaiarIRvSAEGQEGLRAFLEKRTPAW 261
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
8-247 3.16e-38

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 134.81  E-value: 3.16e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIraVVIRGADGHFCAGGDIKDMAGA--RGQKSAEG 85
Cdd:PRK07112   4 QTIRVRQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATI--VVLEGLPEVFCFGADFSAIAEKpdAGRADLID 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  86 EEdPFYRLnrafgqmIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGL 165
Cdd:PRK07112  82 AE-PLYDL-------WHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIPACVLPFLIRRIGT 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 166 TQARRLALLGLRVDADEACRLGIVHQV-AESEVEIDELLGhaveRVRQCAPNATAQTK----ALLHRVgHESMSGLLDSA 240
Cdd:PRK07112 154 QKAHYMTLMTQPVTAQQAFSWGLVDAYgANSDTLLRKHLL----RLRCLNKAAVARYKsyasTLDDTV-AAARPAALAAN 228

                 ....*..
gi 494269470 241 AAKFAEA 247
Cdd:PRK07112 229 IEMFADP 235
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
1-267 4.85e-38

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 134.33  E-value: 4.85e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   1 MDQFpqcetLLLEKQGPALFVTINRPDVRNAMSLQ-MVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARG 79
Cdd:PRK09245   1 MTDF-----LLVERDGHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAGTAFSSGGNVKDMRARVG 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  80 QKSAEGeedpfYRLNRAFGQMIQQ----VNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQI 155
Cdd:PRK09245  76 AFGGSP-----ADIRQGYRHGIQRiplaLYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDG 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 156 APFVVER-IGLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHA---VERVRQCAPNATAQTKALLHRVGHE 231
Cdd:PRK09245 151 GAWLLPRiIGMARAAEMAFTGDAIDAATALEWGLVSRV----VPADQLLPAAralAERIAANPPHALRLTKRLLREGQHA 226
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 494269470 232 SMSGLLDSAAAKFAEAIRSDEGSEGTLAFMQKRPAS 267
Cdd:PRK09245 227 SLDTLLELSAAYQALAHHTADHREAVDAFLEKRPPV 262
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
8-268 4.86e-37

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 131.65  E-value: 4.86e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKdmAGARGQK-SAEGe 86
Cdd:PRK08252   3 DEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLK--AFARGERpSIPG- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  87 edpfyrlnRAFGQMIQQvnESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAqiAPFVV---ERI 163
Cdd:PRK08252  80 --------RGFGGLTER--PPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAA--GGGLLrlpRRI 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 164 GLTQARRLALLGLRVDADEACRLGIVHQVAESEVEIDELLGHAvERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAK 243
Cdd:PRK08252 148 PYHIAMELALTGDMLTAERAHELGLVNRLTEPGQALDAALELA-ERIAANGPLAVAASKRIVVESGDWSEDEMFARQREL 226
                        250       260
                 ....*....|....*....|....*
gi 494269470 244 FAEAIRSDEGSEGTLAFMQKRPASW 268
Cdd:PRK08252 227 IAPVFTSADAKEGATAFAEKRAPVW 251
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
10-269 5.01e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 129.01  E-value: 5.01e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGA-DGHFCAGGDIKDMAgARGQKSAEGEed 88
Cdd:PRK06494   6 STVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAgDKAFSAGNDLKEQA-AGGKRGWPES-- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  89 pfyrlnrAFGQMIQQVnESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVER-IGLTQ 167
Cdd:PRK06494  83 -------GFGGLTSRF-DLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRqIGLKR 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 168 ARRLALLGLRVDADEACRLGIVHQVAeSEVEIDELLGHAVERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAKFAEA 247
Cdd:PRK06494 155 AMGMILTGRRVTAREGLELGFVNEVV-PAGELLAAAERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRDYPAVE 233
                        250       260
                 ....*....|....*....|....
gi 494269470 248 IR--SDEGSEGTLAFMQKRPASWA 269
Cdd:PRK06494 234 ARraSQDYIEGPKAFAEKRPPRWK 257
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
8-268 1.95e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 127.48  E-value: 1.95e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPAL-FVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGArgqksaeGE 86
Cdd:PRK08138   7 DVVLLERPADGVaLLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATA-------GA 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  87 EDPFYRLNRAFGQMIQQVnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-AQIAPFVVERIGL 165
Cdd:PRK08138  80 IEMYLRHTERYWEAIAQC---PKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPgAGGTQRLVRAVGK 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 166 TQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA---PNATAQTKallhRVGHESMSGLLDSAAA 242
Cdd:PRK08138 157 FKAMRMALTGCMVPAPEALAIGLVSEV----VEDEQTLPRALELAREIArmpPLALAQIK----EVVLAGADAPLDAALA 228
                        250       260       270
                 ....*....|....*....|....*....|
gi 494269470 243 ----KFAEAIRSDEGSEGTLAFMQKRPASW 268
Cdd:PRK08138 229 lerkAFQLLFDSEDQKEGMDAFLEKRKPAY 258
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
21-265 8.68e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 125.90  E-value: 8.68e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVrNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGArgqksAEGEEdpFYRLNRAFGQM 100
Cdd:PRK07658  15 ITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFTSV-----TEAEQ--ATELAQLGQVT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 101 IQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPA----QIAPFVVeriGLTQARRLALLGL 176
Cdd:PRK07658  87 FERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGfagtQRLPRYV---GKAKALEMMLTSE 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 177 RVDADEACRLGIVHQVAESEveidELLGHAVERVRQCA---PNATAQTKALLHRVGHESMSGLLDSAAAKFAEAIRSDEG 253
Cdd:PRK07658 164 PITGAEALKWGLVNGVFPEE----TLLDDAKKLAKKIAgksPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDA 239
                        250
                 ....*....|..
gi 494269470 254 SEGTLAFMQKRP 265
Cdd:PRK07658 240 KEGVQAFLEKRK 251
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
5-271 2.49e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 125.50  E-value: 2.49e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   5 PQCETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDI--------KDMAG 76
Cdd:PRK08260   1 MTYETIRYDVADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLsaggntfdLDAPR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  77 ARGQKSAEGEEDPFYRLNR-AFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQI 155
Cdd:PRK08260  81 TPVEADEEDRADPSDDGVRdGGGRVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 156 APFVVERI-GLTQARRLALLGLRVDADEACRLGIVHQVAESEVEIDELLGHAVERVRQCAPNATAQTKALLHRvghesMS 234
Cdd:PRK08260 161 SSWFLPRLvGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNTSPVSVALTRQMMWR-----MA 235
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 494269470 235 GLLDSAAAKFAE--AI----RSDEGSEGTLAFMQKRPASWAAS 271
Cdd:PRK08260 236 GADHPMEAHRVDsrAIysrgRSGDGKEGVSSFLEKRPAVFPGK 278
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
10-264 1.33e-33

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 122.93  E-value: 1.33e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGA-DGHFCAGGDI---KDMAGARGQKSAEG 85
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAgEKAFVAGADIsemKDLNEEEGRKFGLL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  86 EEDPFYRLNRAfgqmiqqvnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPA----QIAPFVVe 161
Cdd:PRK05809  86 GNKVFRKLENL-----------DKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGfggtQRLARIV- 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 162 riGLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCAPNATAQTKaLLHRVGHESMSGLLDSA- 240
Cdd:PRK05809 154 --GPGKAKELIYTGDMINAEEALRIGLVNKV----VEPEKLMEEAKALANKIAANAPIAVK-LCKDAINRGMQVDIDTAv 226
                        250       260
                 ....*....|....*....|....*..
gi 494269470 241 ---AAKFAEAIRSDEGSEGTLAFMQKR 264
Cdd:PRK05809 227 aieAEDFGECFSTEDQTEGMTAFVEKR 253
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
1-268 2.86e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 122.02  E-value: 2.86e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   1 MDQFPQCETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGH-FCAGGDIkdmagarG 79
Cdd:PRK06144   1 MAMTTSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKaFVAGTDI-------A 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  80 QKSAEGEEDPFYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMP-ETTLG--VIPAQIA 156
Cdd:PRK06144  74 QFRAFSTAEDAVAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFPiARTLGncLSMSNLA 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 157 pFVVERIGLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCAPNAtaqtkALLHRVGHESMSGL 236
Cdd:PRK06144 154 -RLVALLGAARVKDMLFTARLLEAEEALAAGLVNEV----VEDAALDARADALAELLAAHA-----PLTLRATKEALRRL 223
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 494269470 237 LDSAAAKFAEAIRSDEGS----EGTLAFMQKRPASW 268
Cdd:PRK06144 224 RREGLPDGDDLIRMCYMSedfrEGVEAFLEKRPPKW 259
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
8-265 2.35e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 119.81  E-value: 2.35e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGH-FCAGGDIKDMAGARgqKSAEGE 86
Cdd:PRK06127  11 GKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKaFVSGADISQFEESR--SDAEAV 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  87 EdpfyRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIA-PFVVERIGL 165
Cdd:PRK06127  89 A----AYEQAVEAAQAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGvKNLVDLVGP 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 166 TQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCAPNA--TAQT-KALLHRVGHESMSGLLDSAAA 242
Cdd:PRK06127 165 SAAKDLFYTARRFDAAEALRIGLVHRV----TAADDLETALADYAATIAGNAplTLRAaKRAIAELLKDEPERDMAACQA 240
                        250       260
                 ....*....|....*....|...
gi 494269470 243 KFAEAIRSDEGSEGTLAFMQKRP 265
Cdd:PRK06127 241 LVAACFDSEDYREGRAAFMEKRK 263
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
8-265 6.32e-32

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 118.44  E-value: 6.32e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQksaeGEE 87
Cdd:PRK07509   3 DRVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVKSVASSPGN----AVK 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 DPFYRL----NRAfgqmiQQV----NESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPaQIAPFV 159
Cdd:PRK07509  79 LLFKRLpgnaNLA-----QRVslgwRRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVP-DMAGTV 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 160 VER--IGLTQARRLALLGLRVDADEACRLGIVHQVAeseveiDELLGHAVERVRQCA---PNATAQTKALLHRVGHESMS 234
Cdd:PRK07509 153 SLRglVRKDVARELTYTARVFSAEEALELGLVTHVS------DDPLAAALALAREIAqrsPDAIAAAKRLINRSWTASVR 226
                        250       260       270
                 ....*....|....*....|....*....|...
gi 494269470 235 GLLdsAAAKFAEA--IRSDEGSEGTLAFMQKRP 265
Cdd:PRK07509 227 ALL--ARESVEQIrlLLGKNQKIAVKAQMKKRA 257
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
10-266 1.06e-31

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 117.56  E-value: 1.06e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAgargqksaegEEDP 89
Cdd:PRK09674   4 LLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNEMA----------EKDL 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 FYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-AQIAPFVVERIGLTQA 168
Cdd:PRK09674  74 AATLNDPRPQLWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPgAGGTQRLIRSVGKSLA 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 169 RRLALLGLRVDADEACRLGIVhqvaeSEVEIDELlghAVERVRQCA-------PNATAQTKALLHRVGHESMSGLLDSAA 241
Cdd:PRK09674 154 SQMVLTGESITAQQAQQAGLV-----SEVFPPEL---TLERALQLAskiarhsPLALRAAKQALRQSQEVDLQAGLAQER 225
                        250       260
                 ....*....|....*....|....*
gi 494269470 242 AKFAEAIRSDEGSEGTLAFMQKRPA 266
Cdd:PRK09674 226 QLFTLLAATEDRHEGISAFLEKRTP 250
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
21-265 3.49e-31

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 116.33  E-value: 3.49e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVrNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGArgqKSAEGEedpFYRLNRAFGQM 100
Cdd:PRK06495  17 VTLDNPPV-NALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLKGRPDV---IKGPGD---LRAHNRRTREC 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 101 IQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVipAQIAPFVVERIGLTQARRLALLGLRVDA 180
Cdd:PRK06495  90 FHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL--AGGGKHAMRLFGHSLTRRMMLTGYRVPA 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 181 DEACRLGIVhqvaESEVEIDELLGHAVERVRQCA---PNATAQTKALLHRVghESMSgLLD------SAAAKFAeaiRSD 251
Cdd:PRK06495 168 AELYRRGVI----EACLPPEELMPEAMEIAREIAsksPLATRLAKDALNTI--ENMS-LRDgyryeqDITAKLA---KTE 237
                        250
                 ....*....|....
gi 494269470 252 EGSEGTLAFMQKRP 265
Cdd:PRK06495 238 DAKEAQRAFLEKRP 251
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
10-266 4.91e-31

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 115.83  E-value: 4.91e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMA---GARGQKSAEGE 86
Cdd:PRK06563   1 VSRERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVApklAAGGFPFPEGG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  87 EDPFYRLNRAFgqmiqqvnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPF-VVERIGL 165
Cdd:PRK06563  81 IDPWGTVGRRL----------SKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLrFPQAAGW 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 166 TQARRLALLGLRVDADEACRLGIVHQVAESEVEIDELLGHAvERVRQCAP---NATAQTKALLHRVGHEsmsglldSAAA 242
Cdd:PRK06563 151 GNAMRYLLTGDEFDAQEALRLGLVQEVVPPGEQLERAIELA-ERIARAAPlgvQATLASARAAVREGEA-------AAAA 222
                        250       260
                 ....*....|....*....|....*...
gi 494269470 243 KFAEAIR----SDEGSEGTLAFMQKRPA 266
Cdd:PRK06563 223 QLPPELRplftSEDAKEGVQAFLERRPA 250
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
21-266 6.90e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 115.60  E-value: 6.90e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGA-DGHFCAGGDIKDMAGArgqksaegEEDPFYRLNRAFGQ 99
Cdd:PRK07657  17 ITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAgEKAFCAGADLKERAGM--------NEEQVRHAVSLIRT 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 100 MIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPA----QIAPFVverIGLTQARRLALLG 175
Cdd:PRK07657  89 TMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGaggtQRLPRL---IGVGRAKELIYTG 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 176 LRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCAPN---ATAQTKALLHRVGHESMSGLLDSAAAKFAEAIRSDE 252
Cdd:PRK07657 166 RRISAQEAKEIGLVEFV----VPAHLLEEKAIEIAEKIASNgpiAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTKD 241
                        250
                 ....*....|....
gi 494269470 253 GSEGTLAFMQKRPA 266
Cdd:PRK07657 242 RLEGLQAFKEKRKP 255
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
8-267 3.00e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 113.98  E-value: 3.00e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEe 87
Cdd:PRK05862   4 ETILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGADIKEMADLSFMDVYKGD- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 dpfyrlnraFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVER-IGLT 166
Cdd:PRK05862  83 ---------YITNWEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRaVGKA 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 167 QARRLALLGLRVDADEACRLGIVHQVAESEVEIDELLGhAVERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAKFAE 246
Cdd:PRK05862 154 KAMDLCLTGRMMDAAEAERAGLVSRVVPADKLLDEALA-AATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRLFHS 232
                        250       260
                 ....*....|....*....|.
gi 494269470 247 AIRSDEGSEGTLAFMQKRPAS 267
Cdd:PRK05862 233 LFATEDQKEGMAAFVEKRKPV 253
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
8-268 6.51e-30

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 113.27  E-value: 6.51e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAG-ARGQKSAEGE 86
Cdd:PRK07799   5 PHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKkPPGDSFKDGS 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  87 EDP--------FYRLnrafgqmiqqvnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-AQIAP 157
Cdd:PRK07799  85 YDPsridallkGRRL--------------TKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPmGGSAV 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 158 FVVERIGLTQARRLALLGLRVDADEACRLGIVHQVAESEVEIDELLGHAvERVRQCAPNATAQTKALLHRVG--HESMSG 235
Cdd:PRK07799 151 RLVRQIPYTVACDLLLTGRHITAAEAKEIGLIGHVVPDGQALDKALELA-ELINANGPLAVQAILRTIRETEgmHENEAF 229
                        250       260       270
                 ....*....|....*....|....*....|...
gi 494269470 236 LLDSAAAkfAEAIRSDEGSEGTLAFMQKRPASW 268
Cdd:PRK07799 230 KIDTKIG--IPVFLSEDAKEGPRAFAEKRAPNF 260
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
21-248 8.18e-30

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 114.49  E-value: 8.18e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGH-FCAGGDIKDMAGARGQKSAEGEEDPF---YRLNRA 96
Cdd:pfam16113   4 ITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERaFCAGGDVRALYEAAKAGGGEAGRDFFreeYRLNYL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   97 FGQMiqqvnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP--------AQiAPfvvERIGLtqa 168
Cdd:pfam16113  84 IATY-------PKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPdvggsyflSR-LP---GELGL--- 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  169 rRLALLGLRVDADEACRLGIVHQVAESEvEIDELLghavERVRQCAPNATAQTKALLHRVGHESMSGllDSAAAKFAEAI 248
Cdd:pfam16113 150 -YLALTGARLNGADALAAGLATHYVPSA-RLPALE----EALAALDWSDPADVDAVLAEFAEESDPP--PSPLAAHREAI 221
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
10-255 8.92e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 112.76  E-value: 8.92e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEEDP 89
Cdd:PRK06190   6 LLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDLKELGGDGSAYGAQDALPN 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 fyrlnrafgqMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPA----QIAPFVVeriGL 165
Cdd:PRK06190  86 ----------PSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGwglsVRLPQKV---GI 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 166 TQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA---PNATAQTKALLHRVGHESMSGLLDSAAA 242
Cdd:PRK06190 153 GRARRMSLTGDFLDAADALRAGLVTEV----VPHDELLPRARRLAASIAgnnPAAVRALKASYDDGAAAQTGDALALEAE 228
                        250
                 ....*....|...
gi 494269470 243 KFAEAIRSDEGSE 255
Cdd:PRK06190 229 AARAHNRSVSPDG 241
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
8-269 3.41e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 111.22  E-value: 3.41e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEE 87
Cdd:PRK06142   6 ESFTVELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMAGVFGQLGKDGLA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 DP---FYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP----AQIAPFVv 160
Cdd:PRK06142  86 RPrtdLRREILRLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVAdvgsLQRLPRI- 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 161 erIGLTQARRLALLGLRVDADEACRLGIVHQVAESEveiDELLGHAVERVRQCA---PNATAQTKALLHRVGHESMSGLL 237
Cdd:PRK06142 165 --IGDGHLRELALTGRDIDAAEAEKIGLVNRVYDDA---DALLAAAHATAREIAaksPLAVRGTKEVLDYMRDHRVADGL 239
                        250       260       270
                 ....*....|....*....|....*....|..
gi 494269470 238 DSAAAKFAEAIRSDEGSEGTLAFMQKRPASWA 269
Cdd:PRK06142 240 RYVATWNAAMLPSKDLTEAIAAHMEKRPPEFT 271
PLN02921 PLN02921
naphthoate synthase
21-265 4.55e-29

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 112.19  E-value: 4.55e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGA-DGHFCAGGDikdmAGARGQKSAEGEEDpFYRLNRAFGQ 99
Cdd:PLN02921  80 ITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKgTKAFCSGGD----QAVRGKDGYVGPDD-AGRLNVLDLQ 154
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 100 MiqQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVER-IGLTQARRLALLGLRV 178
Cdd:PLN02921 155 I--QIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARlVGQKKAREMWFLARFY 232
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 179 DADEACRLGIVHQVaeseVEIDELLGHAVERVRQC---APNATAQTKALLHRV--GHESMSGLLDSAAAKFaeaIRSDEG 253
Cdd:PLN02921 233 TASEALKMGLVNTV----VPLDELEGETVKWCREIlrnSPTAIRVLKSALNAAddGHAGLQELGGNATLLF---YGSEEG 305
                        250
                 ....*....|..
gi 494269470 254 SEGTLAFMQKRP 265
Cdd:PLN02921 306 NEGRTAYLEGRA 317
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
10-264 1.26e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 109.48  E-value: 1.26e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAgargqksaegeEDP 89
Cdd:PRK06072   2 IKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEFA-----------PDF 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 FYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGLTQAR 169
Cdd:PRK06072  71 AIDLRETFYPIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFY 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 170 RLALLGLRVDADEACRLGIVHQVaeseveiDELLGHAVERVRQCAPN---ATAQTKALLHRVGHESMSGLLDSAAAKFAE 246
Cdd:PRK06072 151 EILVLGGEFTAEEAERWGLLKIS-------EDPLSDAEEMANRISNGpfqSYIAAKRMINLVLYNDLEEFLEYESAIQGY 223
                        250
                 ....*....|....*...
gi 494269470 247 AIRSDEGSEGTLAFMQKR 264
Cdd:PRK06072 224 LGKTEDFKEGISSFKEKR 241
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
21-267 1.49e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 109.79  E-value: 1.49e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMA---GARGQKSAE-----GEEDPFYR 92
Cdd:PRK06210  19 ITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGELQtidPSDGRRDTDvrpfvGNRRPDYQ 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  93 LNRAFGQMIQqvnessKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP----AQIAPFVVeriGLTQA 168
Cdd:PRK06210  99 TRYHFLTALR------KPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAehgiSWILPRLV---GHANA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 169 RRLALLGLRVDADEACRLGIVHQVAESEVEIDELLGHAVERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAKFAEAI 248
Cdd:PRK06210 170 LDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNVSPASMAVIKRQLYEDAFQTLAEATARANREMHESL 249
                        250
                 ....*....|....*....
gi 494269470 249 RSDEGSEGTLAFMQKRPAS 267
Cdd:PRK06210 250 QRPDFIEGVASFLEKRPPR 268
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
8-264 2.43e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 108.97  E-value: 2.43e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQV-ENDASIraVVIRGADGHFCAGGDIKDMAgargqksAEGE 86
Cdd:PRK07659   6 ESVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVaESSAHI--VVLRGNGRGFSAGGDIKMML-------SSND 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  87 EDPFYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVE-RIGL 165
Cdd:PRK07659  77 ESKFDGVMNTISEIVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQkRVGE 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 166 TQARRLALLGLRVDADEACRLGIVHQVAESEVeiDELLGHAVERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAKFA 245
Cdd:PRK07659 157 NKAKQIIWEGKKLSATEALDLGLIDEVIGGDF--QTAAKQKISEWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKRAQY 234
                        250
                 ....*....|....*....
gi 494269470 246 EAIRSDEGSEGTLAFMQKR 264
Cdd:PRK07659 235 AMRQTADHKEGIRAFLEKR 253
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
10-268 1.02e-26

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 104.64  E-value: 1.02e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQksaegeeDP 89
Cdd:PRK08139  13 LLREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLKEMRAARGL-------AY 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 FYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGLTQAR 169
Cdd:PRK08139  86 FRALFARCSRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFCSTPMVALSRNVPRKQAM 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 170 RLALLGLRVDADEACRLGIVHQVAESEVEIDELLGHAvERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAKFAEAIR 249
Cdd:PRK08139 166 EMLLTGEFIDAATAREWGLVNRVVPADALDAAVARLA-AVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMM 244
                        250
                 ....*....|....*....
gi 494269470 250 SDEGSEGTLAFMQKRPASW 268
Cdd:PRK08139 245 AEDAEEGIDAFLEKRPPEW 263
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
1-269 3.08e-26

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 103.83  E-value: 3.08e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   1 MDQFPQCETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQ 80
Cdd:PLN02664   1 MESYKTLEIIQKSPNSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNSISEQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  81 KSAEGEEDPFYRLNRAFGQM---IQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP----A 153
Cdd:PLN02664  81 SSSGDRGRSGERLRRKIKFLqdaITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITAdlgtL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 154 QIAPFVVeriGLTQARRLALLGLRVDADEACRLGIVHQVAESEVEIDELLGHAVERVRQCAPNATAQTKALLHRVGHESM 233
Cdd:PLN02664 161 QRLPSIV---GYGNAMELALTGRRFSGSEAKELGLVSRVFGSKEDLDEGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSV 237
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 494269470 234 SGLLDSAAAKFAEAIRSDEGSEGTLAFMQKRPASWA 269
Cdd:PLN02664 238 EQGLDYVATWNSAMLVSDDLNEAVSAQIQKRKPVFA 273
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
10-268 4.72e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 102.69  E-value: 4.72e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVrNAMSLQMVAELSTVFSQVENDASIRAVVIRGA-DGHFCAGGDIKDMAGarGQKSAEGEed 88
Cdd:PRK09076   5 LDLEIDGHVAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDgEKFFSAGADLNLFAD--GDKAVARE-- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  89 pfyrLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPA----QIAPFVVeriG 164
Cdd:PRK09076  80 ----MARRFGEAFEALSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCaggtQNLPWLV---G 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 165 LTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAV---ERVRQCAPNATAQTKALLhrvgHESMSGLLDSAA 241
Cdd:PRK09076 153 EGWAKRMILCGERVDAATALRIGLVEEV----VEKGEAREAALalaQKVANQSPSAVAACKTLI----QAARNGPRAAAL 224
                        250       260       270
                 ....*....|....*....|....*....|.
gi 494269470 242 AK----FAEAIRSDEGSEGTLAFMQKRPASW 268
Cdd:PRK09076 225 ALerelFVDLFDTEDQREGVNAFLEKRAPQW 255
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
6-226 2.08e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 100.96  E-value: 2.08e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   6 QCETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQksaeG 85
Cdd:PRK05870   1 MMDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALGAAPGR----P 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  86 EEDPFYRLNRAFgqmiQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERI-G 164
Cdd:PRK05870  77 AEDGLRRIYDGF----LAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAvG 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 494269470 165 LTQARRLALLGLRVDADEACRLGIVHQVAeseveiDELLGHAVERVRQCA---PNATAQTKALLH 226
Cdd:PRK05870 153 PQVARAALLFGMRFDAEAAVRHGLALMVA------DDPVAAALELAAGPAaapRELVLATKASMR 211
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
10-152 2.74e-25

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 102.21  E-value: 2.74e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGH-FCAGGDIKDMAGARGQKSAEGEED 88
Cdd:PRK05617   5 VLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERgFCAGGDIRALYEAARAGDPLAADR 84
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 494269470  89 PF---YRLNRAFGQMiqqvnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP 152
Cdd:PRK05617  85 FFreeYRLNALIARY-------PKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFP 144
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
21-264 7.07e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 99.72  E-value: 7.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGA-DGHFCAGGDIKDMAgARGQKSAEGEEDPFYRLNRAfgq 99
Cdd:PRK06143  20 LTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAgEKAFIGGADIKEMA-TLDQASAEAFISRLRDLCDA--- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 100 miqqVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGvIPAQIAPFVVER-IGLTQARRLALLGLRV 178
Cdd:PRK06143  96 ----VRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRlIGWARTRWLLLTGETI 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 179 DADEACRLGIVHQVAESEvEIDELLGHAVERVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAKFAEAIRSDEGSEGTL 258
Cdd:PRK06143 171 DAAQALAWGLVDRVVPLA-ELDAAVERLAASLAGCGPQALRQQKRLLREWEDMPLDVAIDDSVAEFGAAFLTGEPQRHMA 249

                 ....*.
gi 494269470 259 AFMQKR 264
Cdd:PRK06143 250 AFLNRK 255
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
21-268 7.56e-25

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 100.04  E-value: 7.56e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGeedpFYRLNRAFGQM 100
Cdd:PRK08258  30 ITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHEIIGPLTKMDMPE----LLAFTRMTGDL 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 101 IQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQI-APFVVER-IGLTQARRLALLGLRV 178
Cdd:PRK08258 106 VKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAGADMgACALLPRiIGQGRASELLYTGRSM 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 179 DADEACRLGIVHQVAESeveiDELLGHAVERVRQCA--PN-ATAQTKALLHRVGHESMSGLLDSAAAKFAEAIRSDEGSE 255
Cdd:PRK08258 186 SAEEGERWGFFNRLVEP----EELLAEAQALARRLAagPTfAHGMTKTMLHQEWDMGLEEAIEAEAQAQAICMQTEDFRR 261
                        250
                 ....*....|...
gi 494269470 256 GTLAFMQKRPASW 268
Cdd:PRK08258 262 AYEAFVAKRKPVF 274
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
8-268 3.54e-24

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 97.84  E-value: 3.54e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVrNAMSLQMVAELSTVFSQVENDASIRAVVIRGA-DGHFCAGGDIKdmagargqKSAEGE 86
Cdd:PRK03580   3 ESLHTTRNGSILEITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAgEKFFSAGWDLK--------AAAEGE 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  87 E-DPFYRLNrAFGQMiQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP-AQIAPFVVERIG 164
Cdd:PRK03580  74 ApDADFGPG-GFAGL-TEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPdSGGVLRLPKRLP 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 165 LTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVE---RVRQCAPNATAQTKALLHRVG----HESMSGLL 237
Cdd:PRK03580 152 PAIANEMVMTGRRMDAEEALRWGIVNRV----VPQAELMDRARElaqQLVNSAPLAIAALKEIYRETSempvEEAYRYIR 227
                        250       260       270
                 ....*....|....*....|....*....|.
gi 494269470 238 DSAAAKFAEAIRSDEGSEGTLAFMQKRPASW 268
Cdd:PRK03580 228 SGVLKHYPSVLHSEDALEGPRAFAEKRDPVW 258
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
8-266 7.36e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 96.91  E-value: 7.36e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVEnDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAegee 87
Cdd:PRK08140   4 ETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAGRGFCAGQDLADRDVTPGGAMP---- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 DPFYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVER-IGLT 166
Cdd:PRK08140  79 DLGESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRlVGMA 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 167 QARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCAPNAT---AQTKALLHRVGHESMSGLLDSAAAK 243
Cdd:PRK08140 159 RALGLALLGEKLSAEQAEQWGLIWRV----VDDAALADEAQQLAAHLATQPTrglALIKQAMNASATNTLDAQLDLERDL 234
                        250       260
                 ....*....|....*....|...
gi 494269470 244 FAEAIRSDEGSEGTLAFMQKRPA 266
Cdd:PRK08140 235 QREAGRSADYAEGVSAFLEKRAP 257
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
8-211 9.04e-24

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 97.00  E-value: 9.04e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIK------DMAGARGQK 81
Cdd:PRK09120   8 DTVKVEVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDAWSAGMDLKeyfretDAQPEILQE 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  82 SAEGEEDPFYRLNRAFgqmiqqvnesSKVVIAVTEGAVMGGGFG--LACvsDVAIAGPTAKFGMPETTLGVIPAQIAPFV 159
Cdd:PRK09120  88 RIRREAYGWWRRLRWY----------QKPTIAMVNGWCFGGGFSplVAC--DLAIAADEAQFGLSEINWGIPPGGGVSKA 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 160 V-ERIGLTQARRLALLGLRVDADEACRLGIVHQ---VAESEVEIDELLG--------------HAVERVR 211
Cdd:PRK09120 156 MaDTVGHRDALYYIMTGETFTGRKAAEMGLVNEsvpLAQLRARTRELAAklleknpvvlraakDGFKRVR 225
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
8-224 1.45e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 95.96  E-value: 1.45e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARgqksaegEE 87
Cdd:PRK07260   2 EHIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKRAV-------DE 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 DPFYRLNRafgqMIQQVNESS-------KVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVV 160
Cdd:PRK07260  75 DDVQSLVK----IAELVNEISfaikqlpKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLL 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 494269470 161 ER-IGLTQARRLALLGLRVDADEACRLGIVHQVAESEvEIDELLGHAVERVRQCAPNATAQTKAL 224
Cdd:PRK07260 151 TRaIGLNRATHLAMTGEALTAEKALEYGFVYRVAESE-KLEKTCEQLLKKLRRGSSNSYAAIKSL 214
PLN02600 PLN02600
enoyl-CoA hydratase
21-264 1.85e-23

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 95.64  E-value: 1.85e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGA-DGHFCAGGDIKDMagaRGQKSAEGEEdpFYRLNRAfgq 99
Cdd:PLN02600   8 LRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSvPGVFCAGADLKER---RKMSPSEVQK--FVNSLRS--- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 100 MIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERI-GLTQARRLALLGLRV 178
Cdd:PLN02600  80 TFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLvGRSRAKELIFTGRRI 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 179 DADEACRLGIVHQVAESEVEIDELLGHAVErVRQCAPNATAQTKALLHRVGHESMSGLLDSAAAKFAEAIRSDEGSEGTL 258
Cdd:PLN02600 160 GAREAASMGLVNYCVPAGEAYEKALELAQE-INQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLA 238

                 ....*.
gi 494269470 259 AFMQKR 264
Cdd:PLN02600 239 AFAEKR 244
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
9-266 6.92e-23

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 94.32  E-value: 6.92e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   9 TLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDAsiRAVVIRGADGHFCAGGDIKDMAgargqksaEGEED 88
Cdd:PRK08150   3 LVSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEGV--RAVVLHGEGDHFCAGLDLSELR--------ERDAG 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  89 PFYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVER-IGLTQ 167
Cdd:PRK08150  73 EGMHHSRRWHRVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRlIGVAR 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 168 ARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCAPNATAQTKALLHRVGH-ESMSGLldsaAAKFAE 246
Cdd:PRK08150 153 MTDMMLTGRVYDAQEGERLGLAQYL----VPAGEALDKAMELARRIAQNAPLTNFAVLNALPRiADMSAD----DGLFVE 224
                        250       260
                 ....*....|....*....|....*.
gi 494269470 247 AIRS------DEGSEGTLAFMQKRPA 266
Cdd:PRK08150 225 SLMAavaqsaPEAKERLRAFLEKKAA 250
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
8-222 1.01e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 94.26  E-value: 1.01e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDmAGARGQKSAEGEE 87
Cdd:PRK08290   4 EYVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDLGS-GTPGRDRDPGPDQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 DPFYRLN---------------RAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGvIP 152
Cdd:PRK08290  83 HPTLWWDgatkpgveqryarewEVYLGMCRRWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMG-IP 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 494269470 153 AqiapfvVE------RIGLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVE---RVRQCAPNATAQTK 222
Cdd:PRK08290 162 G------VEyfahpwELGPRKAKELLFTGDRLTADEAHRLGMVNRV----VPRDELEAETLElarRIAAMPPFGLRLTK 230
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
21-265 8.82e-22

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 91.49  E-value: 8.82e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGH-FCAGGD--IKDMAGARGqksaegeEDPFYRLNRAF 97
Cdd:PRK07396  26 ITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKaFCSGGDqkVRGYGGYVD-------DDGVPRLNVLD 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  98 GQMiqQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQI-APFVVERIGLTQARRLALLGL 176
Cdd:PRK07396  99 LQR--LIRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYgASYLARIVGQKKAREIWFLCR 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 177 RVDADEACRLGIVHQVaeseVEIDELlghAVERVRQC------APNATAQTKALLHrVGHESMSGLLDSAAAKFAEAIRS 250
Cdd:PRK07396 177 QYDAQEALDMGLVNTV----VPLADL---EKETVRWCremlqnSPMALRCLKAALN-ADCDGQAGLQELAGNATMLFYMT 248
                        250
                 ....*....|....*
gi 494269470 251 DEGSEGTLAFMQKRP 265
Cdd:PRK07396 249 EEAQEGRNAFNEKRQ 263
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
6-266 9.00e-22

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 91.33  E-value: 9.00e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   6 QCETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVE-NDASIRAVVIRGADGHFCAGGDIKdmAGARGQKSAE 84
Cdd:PRK05981   2 QFKKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEdGKAEVRCLVLTGAGRGFCTGANLQ--GRGSGGRESD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  85 GEEDPFYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVER-I 163
Cdd:PRK05981  80 SGGDAGAALETAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRlV 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 164 GLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCAPNAT---AQTKALLHRVGHESMSGLLDSA 240
Cdd:PRK05981 160 GKARAMELSLLGEKLPAETALQWGLVNRV----VDDAELMAEAMKLAHELANGPTvalGLIRKLYWDSPENDFEEQLNLE 235
                        250       260
                 ....*....|....*....|....*.
gi 494269470 241 AAKFAEAIRSDEGSEGTLAFMQKRPA 266
Cdd:PRK05981 236 REAQRIAGKTEDFKEGVGAFLQKRPA 261
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
8-265 2.64e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 90.20  E-value: 2.64e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGA-DGHFCAGGDIKDMAGArgqkSAEGE 86
Cdd:PRK05980   3 DTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAgDRAFSAGADIHEFSAS----VAAGA 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  87 EDPFYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIP----AQIAPFVVER 162
Cdd:PRK05980  79 DVALRDFVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPtfggTQRLPRLAGR 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 163 iglTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCAPNATAQTKALLHRVG---HESMSGLLDS 239
Cdd:PRK05980 159 ---KRALELLLTGDAFSAERALEIGLVNAV----VPHEELLPAARALARRIIRHSPVAVAAILTAVTrglNLSIAEGLLI 231
                        250       260
                 ....*....|....*....|....*.
gi 494269470 240 AAAKFAEAIRSDEGSEGTLAFMQKRP 265
Cdd:PRK05980 232 ESEQFARMAGSADLREGLAAWIERRR 257
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
21-267 1.10e-20

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 88.55  E-value: 1.10e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDAsIRAVVIRGADGH--FCAGGDIKDMAGARgqKSAEGEEDPFYRLNRAfg 98
Cdd:PRK11423  17 ITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkvWSAGHDIHELPSGG--RDPLSYDDPLRQILRM-- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  99 qmiqqVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGViPAQIAPF--VVERIGLTQARRLALLGL 176
Cdd:PRK11423  92 -----IQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGV-PYNLSGIlnFTNDAGFHIVKEMFFTAS 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 177 RVDADEACRLGIVHQVAESEvEIDELLGHAVERVRQCAPNATAQTKALLhRVGHESMSglLDSAAAKFAEAIR-----SD 251
Cdd:PRK11423 166 PITAQRALAVGILNHVVEVE-ELEDFTLQMAHHISEKAPLAIAVIKEQL-RVLGEAHP--MNPDEFERIQGLRravydSE 241
                        250
                 ....*....|....*.
gi 494269470 252 EGSEGTLAFMQKRPAS 267
Cdd:PRK11423 242 DYQEGMNAFLEKRKPV 257
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
1-196 2.11e-20

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 89.47  E-value: 2.11e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   1 MDQFPQCETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGarGQ 80
Cdd:PLN02874   4 QVQNPAEEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGGDLKMFYD--GR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  81 KSAEGEEDPFYRLNrafgQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVV 160
Cdd:PLN02874  82 ESDDSCLEVVYRMY----WLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYIL 157
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 494269470 161 ERIGLTQARRLALLGLRVDADEACRLGIVHQVAESE 196
Cdd:PLN02874 158 SRLPGHLGEYLALTGARLNGKEMVACGLATHFVPSE 193
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
8-268 9.64e-20

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 86.03  E-value: 9.64e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGA----DGH--FCAGGDIKdmagARGQK 81
Cdd:COG0447   18 TDITYHRAEGIARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNgpskDGGwaFCSGGDQR----VRGRG 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  82 SAEGeEDPFYRLNRAFGQMiqQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQI-APFVV 160
Cdd:COG0447   94 GYVY-EDGVGRLNILEVQR--LIRFMPKPVIAMVAGWAIGGGHVLHVVCDLTIASENARFGQTGPDVGSFDAGYgSAYLA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 161 ERIGLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA---PNATAQTKAllhrvgheSMSGLL 237
Cdd:COG0447  171 RQVGQKKAREIWFLCRQYSAQEALEMGLVNKV----VPHAELEEEAVEWAREILeksPTAIRMLKA--------AFNADD 238
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 494269470 238 DSAAAK--FA-EAIR----SDEGSEGTLAFMQKRPASW 268
Cdd:COG0447  239 DGLAGQqeFAgEATRlaymTDEAQEGRDAFLEKRKPDF 276
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
10-195 1.51e-19

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 87.08  E-value: 1.51e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGD----IKDMAGARGQKSAEG 85
Cdd:PLN02988  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDvaavVRDIEQGNWRLGANF 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  86 EEDPfYRLNRAFGQMiqqvnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGL 165
Cdd:PLN02988  91 FSDE-YMLNYVMATY-------SKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPG 162
                        170       180       190
                 ....*....|....*....|....*....|
gi 494269470 166 TQARRLALLGLRVDADEACRLGIVHQVAES 195
Cdd:PLN02988 163 FFGEYVGLTGARLDGAEMLACGLATHFVPS 192
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
8-266 1.59e-19

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 85.46  E-value: 1.59e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPA-LFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGD---IKDMAgargqksa 83
Cdd:PRK07327  11 PALRFDRPPPGvLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDlalVEEMA-------- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  84 eGEEDPFYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVI----PAQIAPFV 159
Cdd:PRK07327  83 -DDFEVRARVWREARDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAagdhAAIVWPLL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 160 VeriGLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVE---RVRQCAPNATAQTK-ALLHRVghESMSG 235
Cdd:PRK07327 162 C---GMAKAKYYLLLCEPVSGEEAERIGLVSLA----VDDDELLPKALEvaeRLAAGSQTAIRWTKyALNNWL--RMAGP 232
                        250       260       270
                 ....*....|....*....|....*....|.
gi 494269470 236 LLDSAAAKFAEAIRSDEGSEGTLAFMQKRPA 266
Cdd:PRK07327 233 TFDTSLALEFMGFSGPDVREGLASLREKRAP 263
PLN02888 PLN02888
enoyl-CoA hydratase
1-216 1.80e-19

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 85.19  E-value: 1.80e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   1 MDQfPQCETLLL--EKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGAR 78
Cdd:PLN02888   2 MTQ-TVSENLILvpKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTAAEEVF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  79 GQKSAEGEEDPFYRLNRAfgqmiqqvnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPA-QIAP 157
Cdd:PLN02888  81 KGDVKDVETDPVAQMERC-----------RKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSwGLSQ 149
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 494269470 158 FVVERIGLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCAPN 216
Cdd:PLN02888 150 KLSRIIGANRAREVSLTAMPLTAETAERWGLVNHV----VEESELLKKAREVAEAIIKN 204
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
8-193 2.73e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 84.56  E-value: 2.73e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEE 87
Cdd:PRK08259   3 MSVRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAVGTGRGNRLHPSGD 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 DPF----YRLnrafgqmiqqvnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTA-------KFGMPETTLGVIpaqia 156
Cdd:PRK08259  83 GPMgpsrMRL--------------SKPVIAAVSGYAVAGGLELALWCDLRVAEEDAvfgvfcrRWGVPLIDGGTV----- 143
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 494269470 157 pfvveR----IGLTQARRLALLGLRVDADEACRLGIVHQVA 193
Cdd:PRK08259 144 -----RlprlIGHSRAMDLILTGRPVDADEALAIGLANRVV 179
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
13-194 5.76e-19

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 86.43  E-value: 5.76e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   13 EKQGPALFVTINRPDVR-NAMSLQMVAELSTVFSQVENDASIR-AVVIRGADGHFCAGGDIKDMAgargqksAEGEEDPF 90
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKsAVLISGKPGSFVAGADIQMIA-------ACKTAQEV 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   91 YRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGF--GLACVSDVAIAGPTAKFGMPETTLGVIPA----QIAPFVVeriG 164
Cdd:TIGR02441  91 TQLSQEGQEMFERIEKSQKPIVAAISGSCLGGGLelALACHYRIATKDRKTLLGLPEVMLGLLPGaggtQRLPKLT---G 167
                         170       180       190
                  ....*....|....*....|....*....|
gi 494269470  165 LTQARRLALLGLRVDADEACRLGIVHQVAE 194
Cdd:TIGR02441 168 VPAALDMMLTGKKIRADRAKKMGIVDQLVD 197
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
8-263 1.58e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 82.15  E-value: 1.58e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTI---NRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKD-MAGARGQKSA 83
Cdd:PRK06023   3 DHILVERPGAHPGVQVirfNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQDfLAAAMGGTSF 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  84 EGEEDPFYRlnrafgqmiqQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERI 163
Cdd:PRK06023  83 GSEILDFLI----------ALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRL 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 164 gLTQARRLALLGL--RVDADEACRLGIVHQVAESEvEIDELLGHAVERVRQCAPNATAQTKALLhRVGHESMSGLLDSAA 241
Cdd:PRK06023 153 -MGHQRAFALLALgeGFSAEAAQEAGLIWKIVDEE-AVEAETLKAAEELAAKPPQALQIARDLM-RGPREDILARIDEEA 229
                        250       260
                 ....*....|....*....|..
gi 494269470 242 AKFAEAIRSDEGSEGTLAFMQK 263
Cdd:PRK06023 230 KHFAARLKSAEARAAFEAFMRR 251
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
1-210 1.87e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 83.17  E-value: 1.87e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   1 MDQFPQCETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQ 80
Cdd:PRK08272   3 PVDLDNLKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLSAYAEGSSS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  81 KSAEGEEDPFYRLNRAFG----------QMIQQVNE-------SSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGM 143
Cdd:PRK08272  83 GGGGGAYPGKRQAVNHLPddpwdpmidyQMMSRFVRgfmslwhAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGY 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 494269470 144 PETTLGVIPAqiAPFVVERIGLTQARRLALLGLRVDADEACRLGIVHQVAESEvEIDELLGHAVERV 210
Cdd:PRK08272 163 PPTRVWGVPA--TGMWAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPE-ELDERTERLVERI 226
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
10-201 1.97e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 82.57  E-value: 1.97e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPAL-FVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDmAGARGQksAEGEED 88
Cdd:PRK05864  11 VLVDHPRPEIaLITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADHKS-AGVVPH--VEGLTR 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  89 PFYRLN--RAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKF-------GMPETTLGVipaqiaPFV 159
Cdd:PRK05864  88 PTYALRsmELLDDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFraaginnGLTASELGL------SYL 161
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 494269470 160 VER-IGLTQARRLALLGLRVDADEACRLGIVHQVAESEVEIDE 201
Cdd:PRK05864 162 LPRaIGSSRAFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDT 204
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
15-266 3.42e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 81.22  E-value: 3.42e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  15 QGPALFVTINRPDVRNAMSLQMVAELSTVFSQVEnDASIRAVVIRGADGHFCAGGDIKdmagarGQKSAEGEEDPFYRLN 94
Cdd:PRK07854   7 DGQVLTIELQRPERRNALNAELCEELREAVRKAV-DESARAIVLTGQGTVFCAGADLS------GDVYADDFPDALIEML 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  95 RAFgqmiqqvnESSKV-VIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVipaQIAPFVVER----IGLTQAR 169
Cdd:PRK07854  80 HAI--------DAAPVpVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGI---ALDNWTIRRlsslVGGGRAR 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 170 RLALLGLRVDADEACRLGIVHQVAESeveiDELLGHAVERVRQcAPNATAQTKALLHRVGheSMSGLLDSAAAKFAEAIR 249
Cdd:PRK07854 149 AMLLGAEKLTAEQALATGMANRIGTL----ADAQAWAAEIAGL-APLALQHAKRVLNDDG--AIEEAWPAHKELFDKAWA 221
                        250
                 ....*....|....*..
gi 494269470 250 SDEGSEGTLAFMQKRPA 266
Cdd:PRK07854 222 SQDAIEAQVARIEKRPP 238
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
21-220 2.58e-17

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 81.48  E-value: 2.58e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVR-NAMSLQMVAELSTVFSQVENDASIRAVV-IRGADGHFCAGGDIKDMAGARGQKSAEgeedpfyRLNRAFG 98
Cdd:PRK11154  19 ITIDVPGEKmNTLKAEFAEQVRAILKQLREDKELKGVVfISGKPDNFIAGADINMLAACKTAQEAE-------ALARQGQ 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  99 QMIQQVNESSKVVIAVTEGAVMGGG--FGLACVSDVAIAGPTAKFGMPETTLGVIPA----QIAPfvvERIGLTQARRLA 172
Cdd:PRK11154  92 QLFAEIEALPIPVVAAIHGACLGGGleLALACHYRVCTDDPKTVLGLPEVQLGLLPGsggtQRLP---RLIGVSTALDMI 168
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 494269470 173 LLGLRVDADEACRLGIVHQVAESEVeideLLGHAVERVRQCAPNATAQ 220
Cdd:PRK11154 169 LTGKQLRAKQALKLGLVDDVVPHSI----LLEVAVELAKKGKPARRPL 212
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
21-268 9.33e-17

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 78.14  E-value: 9.33e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRG-----ADG--HFCAGGDiKDMAGARGQKSAEGEEDPFYRL 93
Cdd:PRK08321  38 IAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTGngpspKDGgwAFCSGGD-QRIRGRDGYQYAEGDEADTVDP 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  94 NRAFGQMIQQVNE----SSKVVIAVTEGAVMGGGFGLACVSDVAIAGPT-AKFGMPETTLGVIPAQI-APFVVERIGLTQ 167
Cdd:PRK08321 117 ARAGRLHILEVQRlirfMPKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYgSAYLARQVGQKF 196
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 168 ARRLALLGLRVDADEACRLGIVHQVAESEVEIDELLGHAvERVRQCAPNATAQTKALLHR-----VGHESMSGlldsaaa 242
Cdd:PRK08321 197 AREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWA-REINGKSPTAMRMLKYAFNLtddglVGQQLFAG------- 268
                        250       260       270
                 ....*....|....*....|....*....|
gi 494269470 243 kfaEAIR----SDEGSEGTLAFMQKRPASW 268
Cdd:PRK08321 269 ---EATRlaymTDEAQEGRDAFLEKRDPDW 295
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
21-214 1.83e-16

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 76.55  E-value: 1.83e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  21 VTINRPDVrNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGeedpfyrLNRAFGQM 100
Cdd:PRK07938  15 VTVDYPPV-NALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQATPGFTALID-------ANRGCFAA 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 101 IQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAqiAPFVVERIGLTQARRLALLGLRVDA 180
Cdd:PRK07938  87 FRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGALGA--ATHLQRLVPQHLMRALFFTAATITA 164
                        170       180       190
                 ....*....|....*....|....*....|....
gi 494269470 181 DEACRLGIVHQVaeseVEIDELLGHAVERVRQCA 214
Cdd:PRK07938 165 AELHHFGSVEEV----VPRDQLDEAALEVARKIA 194
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
10-239 1.59e-15

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 75.49  E-value: 1.59e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  10 LLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEEDP 89
Cdd:PLN02157  39 VLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGRAFCAGGDIVSLYHLRKRGSPDAIREF 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  90 FYRLNrafgQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGLTQAR 169
Cdd:PLN02157 119 FSSLY----SFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGE 194
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 170 RLALLGLRVDADE--ACRLGiVHQVAESEV-----EIDELLG---HAVER-VRQCAPNATAQTKALLHRV-------GHE 231
Cdd:PLN02157 195 YLGLTGLKLSGAEmlACGLA-THYIRSEEIpvmeeQLKKLLTddpSVVEScLEKCAEVAHPEKTGVIRRIdllekcfSHD 273

                 ....*...
gi 494269470 232 SMSGLLDS 239
Cdd:PLN02157 274 TVEEIIDS 281
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
30-227 9.01e-15

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 72.22  E-value: 9.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  30 NAMSLQMVAELSTVFSQVENDASIRAVVIRGA--DGHFCAGGDIKDMagaRGQKSAEGEEDPFYRLNRAFgqmIQQVNES 107
Cdd:PLN03214  33 NSMTLAMWRSLDDALTALENDPTVRGVVFASGlrRDVFTAGNDIAEL---YAPKTSAARYAEFWLTQTTF---LVRLLRS 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 108 SKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGV-IPAQIAPFVVER-IGLTQARRLALLGLRVDADEACR 185
Cdd:PLN03214 107 RLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRvIDRKVAESLLLRGRLVRPAEAKQ 186
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 494269470 186 LGIVHQVAESEVEIDELLgHAVERVRQCAPNATAQTKALLHR 227
Cdd:PLN03214 187 LGLIDEVVPAAALMEAAA-SAMERALKLPSAARAATKALLRE 227
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
5-268 2.72e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 71.14  E-value: 2.72e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   5 PQCETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQK-SA 83
Cdd:PRK12478   2 PDFQTLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFGGGFQHWGEAmMT 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  84 EGEEDP---FYRLN-RAFG--QMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGviPAQIAP 157
Cdd:PRK12478  82 DGRWDPgkdFAMVTaRETGptQKFMAIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMW--GAYLTG 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 158 FVVERIGLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA--PNATAQTKALLHRVGHESM-- 233
Cdd:PRK12478 160 MWLYRLSLAKVKWHSLTGRPLTGVQAAEAELINEA----VPFERLEARVAEVATELAriPLSQLQAQKLIVNQAYENMgl 235
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 494269470 234 ------SGLLDSAAAKFAEA---IRSDEgSEGTLAFMQKRPASW 268
Cdd:PRK12478 236 astqtlGGILDGLMRNTPDAlefIRTAE-TQGVRAAVERRDGPF 278
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
8-239 2.51e-13

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 69.24  E-value: 2.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470   8 ETLLLEKQGPALFVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAgargQKSAEGEE 87
Cdd:PLN02851  42 DQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSGRAFCSGADVVSLY----HLINEGNV 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  88 DPFYRLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVERIGLTQ 167
Cdd:PLN02851 118 EECKLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGYL 197
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 168 ARRLALLGLRVDADE--ACRLGIVHQVAESEVEIDELLGHAVERVRQCAPNATAQ--------TKALLHRV-------GH 230
Cdd:PLN02851 198 GEYLALTGQKLNGVEmiACGLATHYCLNARLPLIEERLGKLLTDDPAVIEDSLAQygdlvypdKSSVLHKIetidkcfGH 277

                 ....*....
gi 494269470 231 ESMSGLLDS 239
Cdd:PLN02851 278 DTVEEIIEA 286
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
23-228 2.57e-12

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 64.48  E-value: 2.57e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  23 INRPDVrNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGARGQKSAEGEedpfyrlnRAFGQMIQ 102
Cdd:PRK05869  23 LSRPPT-NALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAA--------RVRQQAVD 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 103 QVNESSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVVER-IGLTQARRLALLGLRVDAD 181
Cdd:PRK05869  94 AVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRaAGPSRAKELVFSGRFFDAE 173
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 494269470 182 EACRLGIVHQVAESEVEIDELLGHAvERVRQCAPNATAQTKALLHRV 228
Cdd:PRK05869 174 EALALGLIDEMVAPDDVYDAAAAWA-RRFLDGPPHALAAAKAGISDV 219
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
25-212 1.65e-11

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 63.01  E-value: 1.65e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  25 RPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIR----GAD--GHFCAGGD-------IKDMAGARGQKSAEGEEDPFY 91
Cdd:PRK08788  33 RAQPRPCFNLELLDDIMNLQRAIRQRLDDSGLPVDfwvlASDvpGVFNLGGDlalfaelIRAGDRDALLAYARACVDGVH 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  92 RLNRAFGQMIqqvnesskVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIA-PFVVERIGLTQARR 170
Cdd:PRK08788 113 AFHRGFGAGA--------ISIALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAySFLARRVGPKLAEE 184
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 494269470 171 LALLGLRVDADEACRLGIVHQVAESeveidellGHAVERVRQ 212
Cdd:PRK08788 185 LILSGKLYTAEELHDMGLVDVLVED--------GQGEAAVRT 218
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
15-214 1.40e-10

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 61.42  E-value: 1.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  15 QGPALFV----------TINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKDMAGArgqkSAE 84
Cdd:PRK11730   4 QGKTLQVdwledgiaelVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAFIVGADITEFLSL----FAA 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  85 GEEdpfyrlnrafgQMIQQVNESSKV-----------VIAVTeGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPA 153
Cdd:PRK11730  80 PEE-----------ELSQWLHFANSIfnrledlpvptVAAIN-GYALGGGCECVLATDYRVASPDARIGLPETKLGIMPG 147
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 494269470 154 QIAPFVVER-IGLTQARRLALLGLRVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA 214
Cdd:PRK11730 148 FGGTVRLPRlIGADNALEWIAAGKDVRAEDALKVGAVDAV----VAPEKLQEAALALLKQAI 205
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
20-214 1.68e-10

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 59.60  E-value: 1.68e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  20 FVTINRPDVRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGDIKD-MAGARGQKsaEGEEDPFYRLNRAFg 98
Cdd:PRK07110  17 QVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGGTQEGlLSLQTGKG--TFTEANLYSLALNC- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  99 qmiqqvnesSKVVIAVTEGAVMGGGFGLACVSDVAIAGPTAKFGMPETTLGVIPAQIAPFVV-ERIGLTQARRLALLGLR 177
Cdd:PRK07110  94 ---------PIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILpEKLGLALGQEMLLTARY 164
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 494269470 178 VDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA 214
Cdd:PRK07110 165 YRGAELKKRGVPFPV----LPRAEVLEKALELARSLA 197
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
12-201 7.39e-06

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 45.86  E-value: 7.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  12 LEKQGPALFVTINRPDvRNAMSLQMVAELSTVFSQVENDASIRAVVIRGADGHFCAGGdiKDMAGArgqKSAEGEEDPFY 91
Cdd:PLN02267   4 LEKRGNLFILTLTGDG-EHRLNPTLIDSIRSALRQVKSQATPGSVLITTAEGKFFSNG--FDLAWA---QAAGSAPSRLH 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  92 RLNRAFGQMIQQVNESSKVVIAVTEGAVMGGGFGLACVSD-VAIAGPTAKFGMPETTLG-VIPAQIAPFVVERIGLTQAR 169
Cdd:PLN02267  78 LMVAKLRPLVADLISLPMPTIAAVTGHASAAGFILALSHDyVLMRKDRGVLYMSEVDIGlPLPDYFMALLRAKIGSPAAR 157
                        170       180       190
                 ....*....|....*....|....*....|...
gi 494269470 170 R-LALLGLRVDADEACRLGIVHQVAESEVEIDE 201
Cdd:PLN02267 158 RdVLLRAAKLTAEEAVEMGIVDSAHDSAEETVE 190
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
30-223 2.85e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 41.11  E-value: 2.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470  30 NAMSLQMVAELSTVFSQVENDASIraVVIRGADGHFCAGGDIKDMagARGQKSAEGeedpfyrlnrafgqMIQQVNESSK 109
Cdd:PRK06213  24 NALSPAMIDALNAALDQAEDDRAV--VVITGQPGIFSGGFDLKVM--TSGAQAAIA--------------LLTAGSTLAR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494269470 110 --------VVIAVTEGAVMGGGFgLACVSDVAIA--GPTaKFGMPETTLG-VIPaqIAPFVVERIGLTQA--RRLALLGL 176
Cdd:PRK06213  86 rllshpkpVIVACTGHAIAKGAF-LLLSADYRIGvhGPF-KIGLNEVAIGmTMP--HAAIELARDRLTPSafQRAVINAE 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 494269470 177 RVDADEACRLGIVHQVaeseVEIDELLGHAVERVRQCA---PNATAQTKA 223
Cdd:PRK06213 162 MFDPEEAVAAGFLDEV----VPPEQLLARAQAAARELAglnMGAHAATKL 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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