|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
24-1024 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 873.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 24 QKVKGVVKDASGEPLIGVNVLLKGGTVGAITDLDGAFDLIVNDdKSVLVFSFVGFETKEVPVKGRNFLTVTLTEDNTQLE 103
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPP-GAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 104 EIVVVGYGTQKRQEITGSVASVSRKEIMTVSTANITNALQGKIPGLNIKQNTGEPGtYDNSFNIRGLGT------PMVIV 177
Cdd:TIGR04056 80 EVVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPG-GDAEIWIRGISSfggnnsPLYVI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 178 DGIPRDN-FDRIDPNEIESVSVLKDATA-AVYGVRAANGVILVTTRKGTKGRTEINLNASYGIQGITKYPKSVDAYGYME 255
Cdd:TIGR04056 159 DGVPRDNgLSDLNPEDIESISVLKDASAtAIYGSRGANGVILITTKRGKEGKPKISYNAEFGFSTPTRLPEMLNAYEYAE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 256 LYNEAMANRGETTPT-YSPDLITS------GTPYANVNWYDEIVRKNVPQYQVNLTASGGTDRIQFFNSIGYYSEEGLWk 328
Cdd:TIGR04056 239 LYNEALLNRGSSPPDiYTDEEIEAyrngldPDLYPNTDWQDEIFKRTAFNQRHNLSVSGGTEKARYYVSLGYYNEEGIL- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 329 sKSLDYERFNLRSNITAQITDQLTAEFQIGGFIDTKNAPPYDPADILKAIGAQ-----VPIYEIYANGNPDYLGKQYNDD 403
Cdd:TIGR04056 318 -KNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNPGGSTSNIWGALMLFprgtpYSTPPVYSDGYYPAYNSGNTSL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 404 NNALIKssnEYAGYRKTSNTQIQVTASLRWDIpfVKGLWAKALVAYDpkfyksklfSKQYRTYQYDKTSDSYSVANTSAM 483
Cdd:TIGR04056 397 QNPYAL---LNRGYNENERNRLNGNASLEQKI--TKGLKLKGTFSYD---------YSNYKNKKYYKNPYYYNATGGANN 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 484 SSVTEWRSDTATPTTQLSLNYENKFqNKHNVKALLLFETRKWQTSdlsgNRNTLMDAVDQIYAGliDDARSINGSADRNA 563
Cdd:TIGR04056 463 GYYSESNSRSRNYYLEATLNYNRTF-GKHNVSALLGYSQQENKSS----SYGGLLDDLPSLDAG--TSDASVSGSDSEYR 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 564 NVGLVGRFDYDYLSKYLVQASFRYDGSSKF-YNKKWGFFPSLSLGWRISEESFFKDNISFVDNLKLRASIGRMGDDNV-E 641
Cdd:TIGR04056 536 LQSLFGRATYSYKDRYLLEFNFRYDGSSRFaKGNRWGFFPSVSLGWRISEEKFMKKLKKWLSFLKLRASYGIVGNDNIgD 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 642 PYLWMMAFNYpGDDSYVLG--DGSLIPGVGVPQIPNVNATWYTSTTKNLGIDLSLWNAALTVEFDLFRRDRDGLLANRiv 719
Cdd:TIGR04056 616 RYPYLSLYNL-GDGGYNFGtnNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKTKDILQSR-- 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 720 SVPGTFGATFAKENINSDMQEGFELVLGHNGKV-RDFSYQLRGNFTYtlNRNK---YVESVPSGNSYDnWRNNTNdRNSN 795
Cdd:TIGR04056 693 SLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIgKDFSWSVRGNFTY--NKNKileLDEGAYLPVKYP-YISKEG-GPIG 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 796 ILWMYQANGQFVSMDDIynnpvlggVYNKYSYLPGDIKYVDFNEDGMIDEWDMQPLMRNNTPIMNFGLTLSGQWKGLDLS 875
Cdd:TIGR04056 769 QIYGYIADGLFKDDDSP--------KQTFGNVRPGDIKYKDVNGDGKIDDDDRVPIGYSNTPDLTYGFGNSFSYKGFDLS 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 876 MSFQGA---SMFN---ARMNASPLQWGGSAWDIFMDRWHKVDASgnvnsfdpdgewvpGKYP--STRVQDPQNYGIESSF 947
Cdd:TIGR04056 841 ALFQGSgggDVFNdgrGFYPFNGGDWGNVLKIVADNRWTPENPN--------------ADYPrlSYGDSNNSNNYQASTR 906
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 494743141 948 WYNNCTYLRLKNLEIGYTFPSKWTKFVGINSLRLYANGYNLFTIqsSASDYIDPENPGGGIDRYPIMRNFNFGINVN 1024
Cdd:TIGR04056 907 WLEDGSYLRLKNLTLGYTLPKKWLKKIGISNLRVYFSGQNLFTF--SKYKGWDPELQGNDGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
102-806 |
5.62e-46 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 176.17 E-value: 5.62e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 102 LEEIVVVGYGTQKR-QEITGSVASVSRKEIMTVSTANITNALQgKIPGLNIKQNTGepgtYDNSFNIRGLGT----PMVI 176
Cdd:COG1629 1 LEEVVVTATRTDESlQDVPGSVSVISREQLEDQPATDLGDLLR-RVPGVSVTSAGG----GAGQISIRGFGGggnrVLVL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 177 VDGIP-------RDNFDRIDPNEIESVSVLKDATAAVYGVRAANGVILVTTRKGTKGrTEINLNASYGiqgitkypksvd 249
Cdd:COG1629 76 VDGVPlndpsggDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDG-KGGEVSASYG------------ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 250 AYGYmelyneamanrgettptyspdlitsgtpyanvnwydeivrknvpqYQVNLTASGGTDRIQFFNSIGYYSEEGLWKS 329
Cdd:COG1629 143 SYGT---------------------------------------------YRASLSLSGGNGKLAYRLSASYRDSDGYRDN 177
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 330 ksLDYERFNLRSNITAQITDQLTAEFQIGGFIDTKNAPPYDPADILKAIGAQVPIYEIYANGNPDylgkqynddnnalik 409
Cdd:COG1629 178 --SDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDGTNPYSNDTDD--------------- 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 410 ssneyagyrktsNTQIQVTASLRWDiPFVKGLWAKALVAYDpkfyksklfskqyrtyQYDKTSDSYSVANTSAMSSVTEW 489
Cdd:COG1629 241 ------------NTRDRYSLSLEYE-HLGDGLKLSASAYYR----------------YDDTDLDSDFTPTPADGGTLEQT 291
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 490 RSDTATPTTQLSLNYENKFQNKHNVKALLlfetrKWQTSDLSGNRNTLMDAvdqiyAGLIDDARSINGSADRNANVGLVG 569
Cdd:COG1629 292 DFDNRTYGLELRLTYDLGFGGKHTLLVGL-----DYQRQDLDGSGYPLDLG-----SGSLPTLTSGADDDGTTTSLALYA 361
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 570 RFDYDYLSKYLVQASFRYDGSSKFYN-------------KKWGFFPSLSLGWRISeesffkdnisfvDNLKLRASIGRmg 636
Cdd:COG1629 362 QDTYKLTDKLTLTAGLRYDYVSYDVDdtvtgtdsasgsrSYSAFSPSLGLTYQLS------------PNLSLYASYSR-- 427
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 637 ddnvepylwmmAFNYPGDDSYVlgdgslIPGVGVPQIPNVNATWYTSTTKNLGIDLSLWNAALTVEFDLFRRDRDGLLAN 716
Cdd:COG1629 428 -----------GFRAPTFGELY------ANGTDPYSVGNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILS 490
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 717 riVSVPGTFGATFAKENINSDMQEGFELVLGHNgkvrdFSYQLRGNFTYTLNRNKYVESVPSGNSYD-NWRNNTNDRNSN 795
Cdd:COG1629 491 --VPLPNDSGFSTYYTNAGKARSYGVELELSYQ-----LTPGLSLNASYSYTDAKFDDDTDGSADLDgNRLPGVPPLTAN 563
|
730
....*....|.
gi 494743141 796 ILWMYQANGQF 806
Cdd:COG1629 564 LGLTYEFPGGW 574
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
114-215 |
9.29e-20 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 85.40 E-value: 9.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 114 KRQEITGSVASVSRKEIMTVSTANITNALQGkIPGLNIkqnTGEPGTYDNSFNIRGLGT--PMVIVDGIP-------RDN 184
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSV---SSGGGGGGSSISIRGFGSnrVLVLVDGVPlnsggggSVD 76
|
90 100 110
....*....|....*....|....*....|.
gi 494743141 185 FDRIDPNEIESVSVLKDATAAVYGVRAANGV 215
Cdd:pfam07715 77 LNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
121-780 |
1.16e-10 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 65.55 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 121 SVASVSRKEImTVSTANITNALQGKIPGLNIkqnTGEPGTYDNSFNIRGLGTP--MVIVDGIP--------RDNFDRIDP 190
Cdd:cd01347 1 SVSVITAEDI-EKQPATSLADLLRRIPGVSV---TRGGGGGGSTISIRGFGPDrtLVLVDGLPlassnygrGVDLNTIPP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 191 NEIESVSVLKDATAAVYGVRAANGVILVTTRKGTkgrTEINLNASYGIqgitkypksvdaygymelyneamanrgettpt 270
Cdd:cd01347 77 ELIERVEVLKGPSSALYGSGAIGGVVNIITKRPT---DEFGGSVTAGY-------------------------------- 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 271 yspdlitsGTPYANVNWydeivrknvpQYQVNLTASGGTDRIQFFNSIGYYSE-----EGLWKSKSLDYERFNLRSNITA 345
Cdd:cd01347 122 --------GSDNSGSSG----------GGGFDVSGALADDGAFGARLYGAYRDgdgtiDGDGQADDSDEERYNVAGKLDW 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 346 QITDQLTAEFqIGGFIDTKNAPPYDPADILKAIGAQVPIYEIYANGNPDYlgkQYNDDNNAliksSNEYAGYRKTSNTQI 425
Cdd:cd01347 184 RPDDDTRLTL-DAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTNGDRDW---DYRDRYRK----RASLGLEHDLNDTGW 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 426 QVTASLRwdipfvkglwakalvaydpkfyksklfskqYRTYQYDKTSDSYSVANTSAMSSVTEWRSDTATPTTQLSL--N 503
Cdd:cd01347 256 TLRANLS------------------------------YSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFdaG 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 504 YENKFQNKHNVKALLLFETRKWQTSDLSgnrntlmdavdqIYAGLIDDARSINGsadrNANVGLVGRFDYDYLSKYLVQA 583
Cdd:cd01347 306 LNAPFGTGPVAHTLTLGVEYRREELDEK------------QTALYAQDTIELTD----DLTLTLGLRYDHYDQDSKDTIA 369
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 584 SfrYDGSSKFYNKkwgFFPSLSLGWRISeesffkdnisfvDNLKLRASIGRmgddnvepylwmmAFNyPGDDSYVLGDGS 663
Cdd:cd01347 370 G--GTTAKKSYSH---WSPSLGLVYKLT------------DGLSLYASYSQ-------------GFR-APSLGELYGGGS 418
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 664 LIPGVGVPQiPNVNAtwYTSTTKNLGIDLSlWNAALTVEFDLFRRDRDgllaNRIVSVPGTFGATFAKENINSDMQ--EG 741
Cdd:cd01347 419 HGGTAAVGN-PNLKP--EKSKQYELGLKYD-PGDGLTLSAALFRIDIK----NEIVSTPTNTGLGLVTVYVNGGKAriRG 490
|
650 660 670
....*....|....*....|....*....|....*....
gi 494743141 742 FELVLghNGKVRDfSYQLRGNFTYTLNRNKYVESVPSGN 780
Cdd:cd01347 491 VELEA--SYDLTD-GLGLTGSYTYTDTEVKRTDGATTGN 526
|
|
| PRK13513 |
PRK13513 |
ligand-gated channel protein; |
96-226 |
1.37e-05 |
|
ligand-gated channel protein;
Pssm-ID: 184104 [Multi-domain] Cd Length: 659 Bit Score: 49.00 E-value: 1.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 96 TEDNTQLEEIVVV---GYgTQKRQEITGSVASVSRKEIMTVSTANITNALQgKIPGLNIkqnTGEPGTYDNSfnIRGLGT 172
Cdd:PRK13513 28 KTNTATPTDTMVVtasGF-QQRIQDAPASISVVTREQLENKAYRDVTDALK-DVPGVVV---TGGGSTSDIS--IRGMAA 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 494743141 173 P--MVIVDGiprdnfDRID-----PNE---------------IESVSVLKDATAAVYGVRAANGVILVTTRKGTKG 226
Cdd:PRK13513 101 KytLILVDG------KRVDtrstrPNSdgsgieqgwlpplaaIERIEVVRGPMSSLYGSDAMGGVINIITRKVQKE 170
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
24-1024 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 873.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 24 QKVKGVVKDASGEPLIGVNVLLKGGTVGAITDLDGAFDLIVNDdKSVLVFSFVGFETKEVPVKGRNFLTVTLTEDNTQLE 103
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPP-GAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 104 EIVVVGYGTQKRQEITGSVASVSRKEIMTVSTANITNALQGKIPGLNIKQNTGEPGtYDNSFNIRGLGT------PMVIV 177
Cdd:TIGR04056 80 EVVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPG-GDAEIWIRGISSfggnnsPLYVI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 178 DGIPRDN-FDRIDPNEIESVSVLKDATA-AVYGVRAANGVILVTTRKGTKGRTEINLNASYGIQGITKYPKSVDAYGYME 255
Cdd:TIGR04056 159 DGVPRDNgLSDLNPEDIESISVLKDASAtAIYGSRGANGVILITTKRGKEGKPKISYNAEFGFSTPTRLPEMLNAYEYAE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 256 LYNEAMANRGETTPT-YSPDLITS------GTPYANVNWYDEIVRKNVPQYQVNLTASGGTDRIQFFNSIGYYSEEGLWk 328
Cdd:TIGR04056 239 LYNEALLNRGSSPPDiYTDEEIEAyrngldPDLYPNTDWQDEIFKRTAFNQRHNLSVSGGTEKARYYVSLGYYNEEGIL- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 329 sKSLDYERFNLRSNITAQITDQLTAEFQIGGFIDTKNAPPYDPADILKAIGAQ-----VPIYEIYANGNPDYLGKQYNDD 403
Cdd:TIGR04056 318 -KNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNPGGSTSNIWGALMLFprgtpYSTPPVYSDGYYPAYNSGNTSL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 404 NNALIKssnEYAGYRKTSNTQIQVTASLRWDIpfVKGLWAKALVAYDpkfyksklfSKQYRTYQYDKTSDSYSVANTSAM 483
Cdd:TIGR04056 397 QNPYAL---LNRGYNENERNRLNGNASLEQKI--TKGLKLKGTFSYD---------YSNYKNKKYYKNPYYYNATGGANN 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 484 SSVTEWRSDTATPTTQLSLNYENKFqNKHNVKALLLFETRKWQTSdlsgNRNTLMDAVDQIYAGliDDARSINGSADRNA 563
Cdd:TIGR04056 463 GYYSESNSRSRNYYLEATLNYNRTF-GKHNVSALLGYSQQENKSS----SYGGLLDDLPSLDAG--TSDASVSGSDSEYR 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 564 NVGLVGRFDYDYLSKYLVQASFRYDGSSKF-YNKKWGFFPSLSLGWRISEESFFKDNISFVDNLKLRASIGRMGDDNV-E 641
Cdd:TIGR04056 536 LQSLFGRATYSYKDRYLLEFNFRYDGSSRFaKGNRWGFFPSVSLGWRISEEKFMKKLKKWLSFLKLRASYGIVGNDNIgD 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 642 PYLWMMAFNYpGDDSYVLG--DGSLIPGVGVPQIPNVNATWYTSTTKNLGIDLSLWNAALTVEFDLFRRDRDGLLANRiv 719
Cdd:TIGR04056 616 RYPYLSLYNL-GDGGYNFGtnNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKTKDILQSR-- 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 720 SVPGTFGATFAKENINSDMQEGFELVLGHNGKV-RDFSYQLRGNFTYtlNRNK---YVESVPSGNSYDnWRNNTNdRNSN 795
Cdd:TIGR04056 693 SLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIgKDFSWSVRGNFTY--NKNKileLDEGAYLPVKYP-YISKEG-GPIG 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 796 ILWMYQANGQFVSMDDIynnpvlggVYNKYSYLPGDIKYVDFNEDGMIDEWDMQPLMRNNTPIMNFGLTLSGQWKGLDLS 875
Cdd:TIGR04056 769 QIYGYIADGLFKDDDSP--------KQTFGNVRPGDIKYKDVNGDGKIDDDDRVPIGYSNTPDLTYGFGNSFSYKGFDLS 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 876 MSFQGA---SMFN---ARMNASPLQWGGSAWDIFMDRWHKVDASgnvnsfdpdgewvpGKYP--STRVQDPQNYGIESSF 947
Cdd:TIGR04056 841 ALFQGSgggDVFNdgrGFYPFNGGDWGNVLKIVADNRWTPENPN--------------ADYPrlSYGDSNNSNNYQASTR 906
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 494743141 948 WYNNCTYLRLKNLEIGYTFPSKWTKFVGINSLRLYANGYNLFTIqsSASDYIDPENPGGGIDRYPIMRNFNFGINVN 1024
Cdd:TIGR04056 907 WLEDGSYLRLKNLTLGYTLPKKWLKKIGISNLRVYFSGQNLFTF--SKYKGWDPELQGNDGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
102-806 |
5.62e-46 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 176.17 E-value: 5.62e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 102 LEEIVVVGYGTQKR-QEITGSVASVSRKEIMTVSTANITNALQgKIPGLNIKQNTGepgtYDNSFNIRGLGT----PMVI 176
Cdd:COG1629 1 LEEVVVTATRTDESlQDVPGSVSVISREQLEDQPATDLGDLLR-RVPGVSVTSAGG----GAGQISIRGFGGggnrVLVL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 177 VDGIP-------RDNFDRIDPNEIESVSVLKDATAAVYGVRAANGVILVTTRKGTKGrTEINLNASYGiqgitkypksvd 249
Cdd:COG1629 76 VDGVPlndpsggDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDG-KGGEVSASYG------------ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 250 AYGYmelyneamanrgettptyspdlitsgtpyanvnwydeivrknvpqYQVNLTASGGTDRIQFFNSIGYYSEEGLWKS 329
Cdd:COG1629 143 SYGT---------------------------------------------YRASLSLSGGNGKLAYRLSASYRDSDGYRDN 177
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 330 ksLDYERFNLRSNITAQITDQLTAEFQIGGFIDTKNAPPYDPADILKAIGAQVPIYEIYANGNPDylgkqynddnnalik 409
Cdd:COG1629 178 --SDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDGTNPYSNDTDD--------------- 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 410 ssneyagyrktsNTQIQVTASLRWDiPFVKGLWAKALVAYDpkfyksklfskqyrtyQYDKTSDSYSVANTSAMSSVTEW 489
Cdd:COG1629 241 ------------NTRDRYSLSLEYE-HLGDGLKLSASAYYR----------------YDDTDLDSDFTPTPADGGTLEQT 291
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 490 RSDTATPTTQLSLNYENKFQNKHNVKALLlfetrKWQTSDLSGNRNTLMDAvdqiyAGLIDDARSINGSADRNANVGLVG 569
Cdd:COG1629 292 DFDNRTYGLELRLTYDLGFGGKHTLLVGL-----DYQRQDLDGSGYPLDLG-----SGSLPTLTSGADDDGTTTSLALYA 361
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 570 RFDYDYLSKYLVQASFRYDGSSKFYN-------------KKWGFFPSLSLGWRISeesffkdnisfvDNLKLRASIGRmg 636
Cdd:COG1629 362 QDTYKLTDKLTLTAGLRYDYVSYDVDdtvtgtdsasgsrSYSAFSPSLGLTYQLS------------PNLSLYASYSR-- 427
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 637 ddnvepylwmmAFNYPGDDSYVlgdgslIPGVGVPQIPNVNATWYTSTTKNLGIDLSLWNAALTVEFDLFRRDRDGLLAN 716
Cdd:COG1629 428 -----------GFRAPTFGELY------ANGTDPYSVGNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILS 490
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 717 riVSVPGTFGATFAKENINSDMQEGFELVLGHNgkvrdFSYQLRGNFTYTLNRNKYVESVPSGNSYD-NWRNNTNDRNSN 795
Cdd:COG1629 491 --VPLPNDSGFSTYYTNAGKARSYGVELELSYQ-----LTPGLSLNASYSYTDAKFDDDTDGSADLDgNRLPGVPPLTAN 563
|
730
....*....|.
gi 494743141 796 ILWMYQANGQF 806
Cdd:COG1629 564 LGLTYEFPGGW 574
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
92-814 |
2.05e-40 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 158.87 E-value: 2.05e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 92 TVTLTEDNTQLEEIVVVGYGT-QKRQEITGSVASVSRKEIMTVSTANITNALQgKIPGLNIKQNTGEPGTydNSFNIRGL 170
Cdd:COG4771 17 ADALAEDATELEEVVVTATRTeQSLSDAPASVSVITAEEIEKLGATDLADALR-LLPGVSVTRSGGRGGS--SGISIRGL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 171 GTP--MVIVDGIPRDN--------FDRIDPNEIESVSVLKDATAAVYGVRAANGVILVTTRKGTKGRTEiNLNASYGIQg 240
Cdd:COG4771 94 GGDrvLVLIDGVPVNNpalggggdLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEG-SVSLGYGSN- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 241 itkypksvdaygymelyneamanrgettptyspdlitsgtpyanvnwydeivrkNVPQYQVNLTASGGTDRIQFFNSIGY 320
Cdd:COG4771 172 ------------------------------------------------------GNGTYSGSLSLGGPGDKLSFLLSGSY 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 321 YSEEGLW------KSKSLDYERFNLRSNITAQITDQLTAEFQIGGFIDTKNAPPYDPADilkaigaqvpiyEIYANGNPD 394
Cdd:COG4771 198 RDRDGYLdyrnggFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGD------------TEISSDNAG 265
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 395 YLGKQYNDDNnalikssneyagyrktsntqiqvtASLRWDIPFVKGLwaKALVAYDpkfyksklfskqyrtyQYDKTSDS 474
Cdd:COG4771 266 DRDTTTDRGN------------------------YSLRYNGDLGDNL--DLSLYYS----------------RTDRDSTN 303
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 475 YSVANTSAMSSVTEWRsdtatpTTQLSLNYENKFQNKHNVKAlllfetrkwqtsdlsgnrntlmdAVDQIYAGLIDDARS 554
Cdd:COG4771 304 GSLGGSTGSFSDSDDT------TYGLELDLTYPLGGNHTLTL-----------------------GAEYRYDDLDSSSFL 354
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 555 INGSADRNaNVGLVGRFDYDYLSKYLVQASFRYDGSSKF-YNKKWGFFPSLSLGWRISeesffkdnisfvDNLKLRASIG 633
Cdd:COG4771 355 GGADASRD-TYGLFAQDEWKLTDKLTLTAGLRYDYYSTFgASNYTAFSPRLGLRYDLS------------DNLTLRASYG 421
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 634 RmgddnvepylwmmAFNYPG-DDSYvlgdGSLIPGVGVPQIPNVNATWYTSTTKNLGIDLSLWNAALTVEFDLFRRDRDG 712
Cdd:COG4771 422 R-------------GFRAPSlAELY----GSGTGTPGRYVLGNPDLKPETSDNYELGLEYRLGNGGLSLSLTGFYTDIKD 484
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 713 LLANriVSVPGTFGATFAKENINSDMQEGFELVLGHNgkvrdFSYQLRGNFTYTLNRNKYvesvpSGNSYDNWRNNTNDR 792
Cdd:COG4771 485 LIVL--VPVGPGPGDVLQYENVGKARTYGLELELKYR-----LGKGLTLTASYTYLDSKI-----DDGDTGEPLPNVPPH 552
|
730 740
....*....|....*....|..
gi 494743141 793 NSNILWMYQANGQFVSMDDIYN 814
Cdd:COG4771 553 KANLGLDYRLPKWWLLLLLTRY 574
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
105-321 |
1.82e-33 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 130.38 E-value: 1.82e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 105 IVVVGYG-TQKRQEITGSVASVSRKEIMTVSTANITNALQgKIPGLNIKQNtGEPGTYdNSFNIRGLGT--PMVIVDGIP 181
Cdd:COG4206 1 VVVTATRlEQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQVSSS-GGPGSA-ASISIRGLGSnqTLVLIDGVP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 182 RDN-------FDRIDPNEIESVSVLKDATAAVYGVRAANGVILVTTRKGTKGrTEINLNASYGIQGITKYPKSVDAYGYM 254
Cdd:COG4206 78 LNDpslggvdLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKG-FKGSVSASYGSFGTRRLSASLSGGAGK 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 494743141 255 ELYNEAMANRGETTPTYSPDLITSGTPYANVNWYDEIVRKNVPQYQVNLTASGGTDRIQFFNSIGYY 321
Cdd:COG4206 157 FSYSLSASYRRSDGYRYNDPDLRNNDGYENTSLNARLGYKLGDNGSLSLSGGYSDSERGYPGAVGSD 223
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
114-215 |
9.29e-20 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 85.40 E-value: 9.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 114 KRQEITGSVASVSRKEIMTVSTANITNALQGkIPGLNIkqnTGEPGTYDNSFNIRGLGT--PMVIVDGIP-------RDN 184
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSV---SSGGGGGGSSISIRGFGSnrVLVLVDGVPlnsggggSVD 76
|
90 100 110
....*....|....*....|....*....|.
gi 494743141 185 FDRIDPNEIESVSVLKDATAAVYGVRAANGV 215
Cdd:pfam07715 77 LNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
26-107 |
2.30e-19 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 83.41 E-value: 2.30e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 26 VKGVVKDA-SGEPLIGVNVLLKGGTVGAITDLDGAFDL-IVNDDKSVLVFSFVGFETKEVPVKGRN----FLTVTLTEDN 99
Cdd:pfam13715 1 ISGTVVDEnTGEPLPGATVYVKGTTKGTVTDADGNFELkNLPAGTYTLVVSFVGYKTQEKKVTVSNdntlDVNFLLKEDA 80
|
....*...
gi 494743141 100 TQLEEIVV 107
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
121-780 |
1.16e-10 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 65.55 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 121 SVASVSRKEImTVSTANITNALQGKIPGLNIkqnTGEPGTYDNSFNIRGLGTP--MVIVDGIP--------RDNFDRIDP 190
Cdd:cd01347 1 SVSVITAEDI-EKQPATSLADLLRRIPGVSV---TRGGGGGGSTISIRGFGPDrtLVLVDGLPlassnygrGVDLNTIPP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 191 NEIESVSVLKDATAAVYGVRAANGVILVTTRKGTkgrTEINLNASYGIqgitkypksvdaygymelyneamanrgettpt 270
Cdd:cd01347 77 ELIERVEVLKGPSSALYGSGAIGGVVNIITKRPT---DEFGGSVTAGY-------------------------------- 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 271 yspdlitsGTPYANVNWydeivrknvpQYQVNLTASGGTDRIQFFNSIGYYSE-----EGLWKSKSLDYERFNLRSNITA 345
Cdd:cd01347 122 --------GSDNSGSSG----------GGGFDVSGALADDGAFGARLYGAYRDgdgtiDGDGQADDSDEERYNVAGKLDW 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 346 QITDQLTAEFqIGGFIDTKNAPPYDPADILKAIGAQVPIYEIYANGNPDYlgkQYNDDNNAliksSNEYAGYRKTSNTQI 425
Cdd:cd01347 184 RPDDDTRLTL-DAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTNGDRDW---DYRDRYRK----RASLGLEHDLNDTGW 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 426 QVTASLRwdipfvkglwakalvaydpkfyksklfskqYRTYQYDKTSDSYSVANTSAMSSVTEWRSDTATPTTQLSL--N 503
Cdd:cd01347 256 TLRANLS------------------------------YSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFdaG 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 504 YENKFQNKHNVKALLLFETRKWQTSDLSgnrntlmdavdqIYAGLIDDARSINGsadrNANVGLVGRFDYDYLSKYLVQA 583
Cdd:cd01347 306 LNAPFGTGPVAHTLTLGVEYRREELDEK------------QTALYAQDTIELTD----DLTLTLGLRYDHYDQDSKDTIA 369
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 584 SfrYDGSSKFYNKkwgFFPSLSLGWRISeesffkdnisfvDNLKLRASIGRmgddnvepylwmmAFNyPGDDSYVLGDGS 663
Cdd:cd01347 370 G--GTTAKKSYSH---WSPSLGLVYKLT------------DGLSLYASYSQ-------------GFR-APSLGELYGGGS 418
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 664 LIPGVGVPQiPNVNAtwYTSTTKNLGIDLSlWNAALTVEFDLFRRDRDgllaNRIVSVPGTFGATFAKENINSDMQ--EG 741
Cdd:cd01347 419 HGGTAAVGN-PNLKP--EKSKQYELGLKYD-PGDGLTLSAALFRIDIK----NEIVSTPTNTGLGLVTVYVNGGKAriRG 490
|
650 660 670
....*....|....*....|....*....|....*....
gi 494743141 742 FELVLghNGKVRDfSYQLRGNFTYTLNRNKYVESVPSGN 780
Cdd:cd01347 491 VELEA--SYDLTD-GLGLTGSYTYTDTEVKRTDGATTGN 526
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
192-221 |
3.19e-10 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 55.66 E-value: 3.19e-10
10 20 30
....*....|....*....|....*....|.
gi 494743141 192 EIESVSVLKDATA-AVYGVRAANGVILVTTR 221
Cdd:TIGR04057 1 DIESISVLKDASAaAIYGSRGANGVILITTK 31
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
90-237 |
4.20e-10 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 63.79 E-value: 4.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 90 FLTVTLTEDNTQLEEIVVVGYGTQKRQ--EITGSVASVSRKEIMTVSTANITNALQgKIPGLNIKQNTGepgtYDNSFNI 167
Cdd:COG4772 11 LAAAAAAEAATTLETVVVTGSRAAEARlkDVPGSVSVVDREELENQAATSLREVLR-RVPGVNVQEEDG----FGLRPNI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 168 --RGLGTP-----MVIVDGIP----------RDNFDriDPNEIESVSVLKDATAAVYGVRAANGVILVTTRKGTKgRTEI 230
Cdd:COG4772 86 giRGLGPRrsrgiTLLEDGIPiapapygdpaAYYFP--DLERMERIEVLRGAAALRYGPQTVGGAINFVTRTIPT-AFGG 162
|
....*..
gi 494743141 231 NLNASYG 237
Cdd:COG4772 163 ELRVTGG 169
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
117-224 |
2.68e-08 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 57.81 E-value: 2.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 117 EITGSVASVSRKEIMTVSTANITNALQGKIPGLNIKQNTGepGTYDNsFNIRGLGtPMVIVDGIPRD--------NFDRI 188
Cdd:TIGR01783 1 DIPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGT--TQFGN-ITIRGFG-LEVDIDNVYLDgvpllsrgNLAIV 76
|
90 100 110
....*....|....*....|....*....|....*.
gi 494743141 189 DPNEIESVSVLKDATAAVYGVRAANGVILVTTRKGT 224
Cdd:TIGR01783 77 DPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQ 112
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
385-811 |
6.84e-08 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 56.32 E-value: 6.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 385 YEIYANGNPDYLGKQYNDDNNALIKSSNEYAGYRKTSNTQIQVTASLRWDIPFVKGLWAKAlvaydpkfyksklfsKQYR 464
Cdd:pfam00593 21 YSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTL---------------RLGL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 465 TYQYDKTSDSYSVANTSAMSSVTEWRSDTATPTTQLSLNYENKFQNKHNVKALLLFETRKWQTSDLSGNRNTLmdavdqi 544
Cdd:pfam00593 86 RYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYD------- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 545 yaglIDDARSINGSADRNANVGLVGRFDYDYLSKYLVQASFRYDGSS-----------KFYNKKWGFFPSLSLGWRISee 613
Cdd:pfam00593 159 ----PANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYStdgddgngggdNFSRSYSAFSPRLGLVYKPT-- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 614 sffkdnisfvDNLKLRASIGRmgddnvepylwmmAFNYPgdDSYVLGDGSLIPGVGVPQIPNVNATWYTSTTKNLGIDLS 693
Cdd:pfam00593 233 ----------DNLSLYASYSR-------------GFRAP--SLGELYGSGSGGGGGAVAGGNPDLKPETSDNYELGLKYD 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 694 lwNAALTVEFDLFRRDRDGLLANRiVSVPGTFGATFAKENINSDMQEGFEL-----VLGHNGKVRDFSYQLRGNFTYTLN 768
Cdd:pfam00593 288 --DGRLSLSLALFYIDIKNLITSD-PDGPGLGGTVYTYTNVGKARIRGVELelsgrLWGLGLSGGGYTYTDADDDADADD 364
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 494743141 769 RNKYVESVP--SGNSYDNWRNNTNDRNSNILWMYQANGQFVSMDD 811
Cdd:pfam00593 365 TGNPLPNVPrhTANLGLTYDFPLGGWGARLGARYVGSGERRYGDA 409
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
111-237 |
1.62e-07 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 55.27 E-value: 1.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 111 GTQKRQEITGSVASVSRKEIMTVSTANITNALQGkIPGlnIKQNTGEPGTYDNsFNIRGLGTPMVI-VDGIPRDNFDRID 189
Cdd:COG4774 2 TDTPLLDTPQSVTVVTRELIEDQGATSLADALRN-VPG--VTFGAGEGGNGDS-FSIRGFSASGDIyVDGLRDPGQYRRD 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 494743141 190 PNEIESVSVLKDATAAVYGVRAANGVILVTTRKGTKGRtEINLNASYG 237
Cdd:COG4774 78 TFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPTDEP-FTEVTLTYG 124
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
92-237 |
3.91e-07 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 54.13 E-value: 3.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 92 TVTLTEDNTQLEEIVVVGYGTQKR-----------------QEITGSVASVSRKEIMTVSTANITNALQgKIPGLNIKQN 154
Cdd:COG4773 22 AAAAAAEATTLPEVTVTGTAEGTGgytakssstatkldtplRETPQSVSVVTRQLIEDQGATTLDDALR-NVPGVTVSSY 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 155 TGepGTYDnSFNIRGLGTPMVIVDGIPRDNFD--RIDPNEIESVSVLKDATAAVYGVRAANGVILVTTRKGTKgRTEINL 232
Cdd:COG4773 101 DG--GGRD-SFSIRGFSIDNYLRDGLPLGGFGggQPDTANLERVEVLKGPAGLLYGAGSPGGLVNLVTKRPTA-EPQGEV 176
|
....*
gi 494743141 233 NASYG 237
Cdd:COG4773 177 SLSAG 181
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
26-100 |
4.84e-06 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 45.35 E-value: 4.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 26 VKGVVKDASGEPLIGVNVLLK----GGTVGAITDLDGAFDL-IVNDDKSVLVFSFVGFETKEVPvkgrnflTVTLTEDNT 100
Cdd:pfam13620 2 ISGTVTDPSGAPVPGATVTVTntdtGTVRTTTTDADGRYRFpGLPPGTYTVTVSAPGFKTATRT-------GVTVTAGQT 74
|
|
| PRK13513 |
PRK13513 |
ligand-gated channel protein; |
96-226 |
1.37e-05 |
|
ligand-gated channel protein;
Pssm-ID: 184104 [Multi-domain] Cd Length: 659 Bit Score: 49.00 E-value: 1.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 96 TEDNTQLEEIVVV---GYgTQKRQEITGSVASVSRKEIMTVSTANITNALQgKIPGLNIkqnTGEPGTYDNSfnIRGLGT 172
Cdd:PRK13513 28 KTNTATPTDTMVVtasGF-QQRIQDAPASISVVTREQLENKAYRDVTDALK-DVPGVVV---TGGGSTSDIS--IRGMAA 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 494743141 173 P--MVIVDGiprdnfDRID-----PNE---------------IESVSVLKDATAAVYGVRAANGVILVTTRKGTKG 226
Cdd:PRK13513 101 KytLILVDG------KRVDtrstrPNSdgsgieqgwlpplaaIERIEVVRGPMSSLYGSDAMGGVINIITRKVQKE 170
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
105-231 |
5.89e-05 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 46.94 E-value: 5.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 105 IVVVGYGTQKRqeITGSVASVS---RKEIMTVSTANITNALQGkIPGLNIKQNTGEPGTYDNSfnIRGLGTP--MVIVDG 179
Cdd:PRK13486 28 MIVSASGYEKK--LTNAAASVSvisQEELQSSQYHDLAEALRS-VEGVDVESGTGKTGGLEIS--IRGMPASytLILIDG 102
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 494743141 180 IPRDNFDRIDPN--------------EIESVSVLKDATAAVYGVRAANGVILVTTRKGT-KGRTEIN 231
Cdd:PRK13486 103 VRQGGSSDVTPNgfsamntgfmpplaAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNAdKWLSSVN 169
|
|
| PRK13483 |
PRK13483 |
ligand-gated channel protein; |
102-222 |
1.83e-04 |
|
ligand-gated channel protein;
Pssm-ID: 184080 [Multi-domain] Cd Length: 660 Bit Score: 45.54 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494743141 102 LEEIVVVGYGTQkrQEITGSVASVS---RKEIMTVSTANITNALQgKIPGLNIkqnTGEPGTYDNSfnIRGLGT--PMVI 176
Cdd:PRK13483 33 METVVVTASGYE--QQIRDAPASISvitREDLENRFYRDLTDALL-DVPGVVV---TGGGDRTDIS--LRGMGSqyTLIL 104
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 494743141 177 VDGiPRDNFDRIDPNE---------------IESVSVLKDATAAVYGVRAANGVILVTTRK 222
Cdd:PRK13483 105 VDG-KRQSSRETRPNSdgpgveqawtpplaaIERIEVIRGPMSSLYGSDAIGGVINIITRK 164
|
|
| |
