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Conserved domains on  [gi|494871838|ref|WP_007597934|]
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ABC transporter permease [Rhizobium sp. PDO1-076]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 5-312 9.27e-116

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 336.27  E-value: 9.27e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   5 RFVLFRPLQFLPVLFGISVITFILVRLIPGDPARVLLGARSTPTAIARIRAQYGLDEPIWLQYFYFVQNLGKGEMGKSIL 84
Cdd:COG0601    3 RYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  85 YKIDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFSVKLGVL 164
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 165 PVSGYGD---SFLDKAAHLVLPSLTIALSLSAVLTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINL 241
Cdd:COG0601  163 PVSGRVSpweDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 494871838 242 LAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRVRL 312
Cdd:COG0601  243 LGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRL 313
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 5-312 9.27e-116

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 336.27  E-value: 9.27e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   5 RFVLFRPLQFLPVLFGISVITFILVRLIPGDPARVLLGARSTPTAIARIRAQYGLDEPIWLQYFYFVQNLGKGEMGKSIL 84
Cdd:COG0601    3 RYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  85 YKIDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFSVKLGVL 164
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 165 PVSGYGD---SFLDKAAHLVLPSLTIALSLSAVLTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINL 241
Cdd:COG0601  163 PVSGRVSpweDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 494871838 242 LAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRVRL 312
Cdd:COG0601  243 LGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRL 313
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 5-312 3.85e-67

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 212.64  E-value: 3.85e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   5 RFVLFRPLQFLPVLFGISVITFILVRLIPGDPARVLLGARS---TPTAIARIRAQYGLDEPIWLQYFYFVQNLGKGEMGK 81
Cdd:PRK10352   3 RYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSNlppTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  82 SILYKIDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFSVKL 161
Cdd:PRK10352  83 SFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 162 GVLPVSGYGDsfldkAAHLVLPSLTIALSLSAVLTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINL 241
Cdd:PRK10352 163 QWLPAMGYGG-----WQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITA 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 494871838 242 LAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRVRL 312
Cdd:PRK10352 238 VGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRR 308
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 115-311 6.82e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.22  E-value: 6.82e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  115 AVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFsvklgvlpvsgygdsFLDKAAHLVLPSLTIALSLSAV 194
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA---------------ILSILGHGILPAIILALLGWAG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  195 LTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINLLAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIF 274
Cdd:pfam00528  66 YARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAIL 145

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 494871838  275 SRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRVR 311
Cdd:pfam00528 146 GYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 112-297 3.90e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 66.92  E-value: 3.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 112 ILIAVPMAALAARNSGRLpDHAVRVVSTLGIGFPPFWLALMLIILFSVKLGVLPVSGYGdsfldkaahlvLPSLTIALSL 191
Cdd:cd06261   16 LVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLG-----------LPALILALLL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 192 SAVLTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINLLAVNIGWLIGGTVVVETVFA-IPGMGQLLV 270
Cdd:cd06261   84 IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGgEAPGPGTGL 163

                        170       180
                 ....*....|....*....|....*..
gi 494871838 271 RAIFSRDYMVVQGVAMVFACATVLVNF 297
Cdd:cd06261  164 LLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 5-312 9.27e-116

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 336.27  E-value: 9.27e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   5 RFVLFRPLQFLPVLFGISVITFILVRLIPGDPARVLLGARSTPTAIARIRAQYGLDEPIWLQYFYFVQNLGKGEMGKSIL 84
Cdd:COG0601    3 RYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  85 YKIDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFSVKLGVL 164
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 165 PVSGYGD---SFLDKAAHLVLPSLTIALSLSAVLTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINL 241
Cdd:COG0601  163 PVSGRVSpweDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 494871838 242 LAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRVRL 312
Cdd:COG0601  243 LGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRL 313
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 5-312 3.85e-67

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 212.64  E-value: 3.85e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   5 RFVLFRPLQFLPVLFGISVITFILVRLIPGDPARVLLGARS---TPTAIARIRAQYGLDEPIWLQYFYFVQNLGKGEMGK 81
Cdd:PRK10352   3 RYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSNlppTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  82 SILYKIDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFSVKL 161
Cdd:PRK10352  83 SFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 162 GVLPVSGYGDsfldkAAHLVLPSLTIALSLSAVLTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINL 241
Cdd:PRK10352 163 QWLPAMGYGG-----WQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITA 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 494871838 242 LAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRVRL 312
Cdd:PRK10352 238 VGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRR 308
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 6-311 1.20e-58

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 190.31  E-value: 1.20e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   6 FVLFRPLQFLPVLFGISVITFILVRLIPGDPARVLLGARSTPTAIARIRAQYGLDEPIWLQYFYFVQNLGKGEMGKSILY 85
Cdd:PRK15081   4 YVIKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTSMVS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  86 KIDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFSVKLGVLP 165
Cdd:PRK15081  84 RRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELGWLP 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 166 VSGygdsfLDKAAHLVLPSLTIALSLSAVLTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINLLAVN 245
Cdd:PRK15081 164 TVG-----ADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQ 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 494871838 246 IGWLIGGTVVVETVFAIPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRVR 311
Cdd:PRK15081 239 FGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
5-311 2.41e-51

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 172.69  E-value: 2.41e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   5 RFVLFRPLQFLPVLFGISVITFILVRLIPGDPARVLLGARS-TPTAIARIRAQYGLDEPIWLQYFYFVQNLGKGEMGKSI 83
Cdd:PRK10914   3 QFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGiSPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  84 LYKIDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFSVKLGV 163
Cdd:PRK10914  83 KSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 164 LPVSG-YGDS-------------------------FLDKAAHLVLPSLTIALSLSAVLTRSLRAAMTVELQSDLATAARA 217
Cdd:PRK10914 163 TPVSGrVSDMvflddsnpltgfmlidtaiwgedgnFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 218 RGMPESIVFWRHVLPNSLVPTINLLAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNF 297
Cdd:PRK10914 243 KGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNL 322

                        330
                 ....*....|....
gi 494871838 298 LADIITVTLDPRVR 311
Cdd:PRK10914 323 LVDLLYGVVNPRIR 336
oppB PRK09471
oligopeptide ABC transporter permease OppB;
5-311 2.85e-46

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 158.31  E-value: 2.85e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   5 RFVLFRPLQFLPVLFGISVITFILVRLIPGDParvLLGARS-TPTAIARIRAQYGLDEPIWLQYFYFVQNLGKGEMGKSI 83
Cdd:PRK09471   3 KFILRRCLEAIPTLFILITISFFMMRLAPGSP---FTGERTlPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  84 LYK-IDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFSVKLG 162
Cdd:PRK09471  80 KYKdYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLH 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 163 VLPVSGYGDSfldKAAHLVLPSLTIALSLSAVLTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINLL 242
Cdd:PRK09471 160 WLPGGGWNGG---ALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYM 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 494871838 243 AVNIGWLIGGTVVVETVFAIPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRVR 311
Cdd:PRK09471 237 GPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 115-311 6.82e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.22  E-value: 6.82e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  115 AVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFsvklgvlpvsgygdsFLDKAAHLVLPSLTIALSLSAV 194
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA---------------ILSILGHGILPAIILALLGWAG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  195 LTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINLLAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIF 274
Cdd:pfam00528  66 YARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAIL 145

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 494871838  275 SRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRVR 311
Cdd:pfam00528 146 GYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
YejB COG4174
ABC-type microcin C transport system, permease component YejB [Secondary metabolites ...
 6-310 1.65e-25

ABC-type microcin C transport system, permease component YejB [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443333 [Multi-domain]  Cd Length: 363  Bit Score: 104.50  E-value: 1.65e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   6 FVLFRPLQFLPVLFGISVITFILVRLIPGDP----------------ARVLLGARST-------------------PTAI 50
Cdd:COG4174    4 YILRRLLLMIPTLLGIMLINFVIVQFAPGGPveqviaqlqgtgggatGRISGGGGDAgggaaagggskyrgargldPEFI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  51 ARIRAQYGLDEPIWLQYFYFVQNLGKGEMGKSILYKIDVLKLILTRIEPTLVLVLASVLLSILIAVPMA-ALAARNSGRL 129
Cdd:COG4174   84 AELEKQYGFDKPAHERFLLMLKNYLRFDFGESYFRDISVIDLILEKLPVSISLGLWSTLLTYLISIPLGiRKAVRDGSRF 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 130 pDHAVRVVSTLGIGFPPFWLALMLIILFS--VKLGVLPVSG----------YGDSFLDKAAHLVLPSLTIALSLSAVLTR 197
Cdd:COG4174  164 -DVWTSTVIIVGYAIPGFLFAILLIVLFAggSYFDWFPLRGltsdnwdqlsWWGKILDYLWHLTLPVTAMVIGGFATLTL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 198 SLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTI-NLLAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIFSR 276
Cdd:COG4174  243 LTKNSFLDEIRKQYVLTARAKGLSERRVLYGHVFRNAMLIVIaGFPAAFIGAFFTGSLLIETIFSLDGLGLLGFEAVVNR 322

                        330       340       350
                 ....*....|....*....|....*....|....
gi 494871838 277 DYMVVQGVAMVFACATVLVNFLADIITVTLDPRV 310
Cdd:COG4174  323 DYPVVFGTLYIFTLIGLVLKLISDLTYVLVDPRI 356
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 6-310 1.59e-23

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 99.05  E-value: 1.59e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   6 FVLFRPLQFLPVLFGISVITFILVRLIPGDP-----ARVLLGARS---------------------------------TP 47
Cdd:PRK15133   4 YLIRRLLLVIPTLWAIITINFFIVQIAPGGPvdqaiAAIEFGQAGglpgaggegvrashaqtgvgnisdsnyrggrglDP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  48 TAIARIRAQYGLDEPIWLQYFYFVQNLGKGEMGKSILYKIDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSG 127
Cdd:PRK15133  84 EVIAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNG 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 128 RLPDHAVRVVSTLGIGFPPFWLALMLIILFS--VKLGVLPVSG----------YGDSFLDKAAHLVLPSLTIALSLSAVL 195
Cdd:PRK15133 164 SRFDVWSSAFIIIGYAIPAFLFAILLIVFFAggSYFDLFPLRGlvsanfdslpWYQKITDYLWHITLPVLATVIGGFAAL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 196 TRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTI-NLLAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIF 274
Cdd:PRK15133 244 TMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIaGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATV 323

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 494871838 275 SRDYMVVQGVAMVFACATVLVNFLADIITVTLDPRV 310
Cdd:PRK15133 324 SRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
PRK15110 PRK15110
peptide ABC transporter permease SapB;
6-308 1.20e-22

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 95.91  E-value: 1.20e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838   6 FVLFRPLQFLPVLFGISVITFILVRLIPGDParvLLGArstptaiariraqygldePIWLQYFYFVQNLGKGEMGKSILY 85
Cdd:PRK15110   4 FTLRRLLLLIVTLFLLTLVGFSLSYFTPHAP---LQGA------------------SLWDAWVFWFNGLLHWDFGVSSIN 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838  86 KIDVLKLILTRIEPTLVLVLASVLLSILIAVPMAALAARNSGRLPDHAVRVVSTLGIGFPPFWLALMLIILFSVKLGVLP 165
Cdd:PRK15110  63 GQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGWLP 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 166 VSG---------------YGDSFLDKAA-----------HLVLPSLTIALSLSAVLTRSLRAAMTVELQSDLATAARARG 219
Cdd:PRK15110 143 VSGrfdllyevkpvtgfaLIDAWLSDSPwrdemimsairHMILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATRG 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 220 MPESIVFWRHVLPNSLVPTINLLAVNIGWLIGGTVVVETVFAIPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFLA 299
Cdd:PRK15110 223 LSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVLS 302


                 ....*....
gi 494871838 300 DIITVTLDP 308
Cdd:PRK15110 303 DILGAMANP 311
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 112-297 3.90e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 66.92  E-value: 3.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 112 ILIAVPMAALAARNSGRLpDHAVRVVSTLGIGFPPFWLALMLIILFSVKLGVLPVSGYGdsfldkaahlvLPSLTIALSL 191
Cdd:cd06261   16 LVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLG-----------LPALILALLL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 192 SAVLTRSLRAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINLLAVNIGWLIGGTVVVETVFA-IPGMGQLLV 270
Cdd:cd06261   84 IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGgEAPGPGTGL 163

                        170       180
                 ....*....|....*....|....*..
gi 494871838 271 RAIFSRDYMVVQGVAMVFACATVLVNF 297
Cdd:cd06261  164 LLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 4-74 5.57e-13

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 64.16  E-value: 5.57e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 494871838    4 YRFVLFRPLQFLPVLFGISVITFILVRLIPGDPARVLLGARSTPTAIARIRAQYGLDEPIWLQYFYFVQNL 74
Cdd:pfam19300   2 LRFLVRRTLGAVVILLIISAVTFFLFYAIPRDPARLACGKNCTPETLALIRHNLGLDKPIPVQYWHFLSGI 72
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 139-250 6.29e-05

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 43.56  E-value: 6.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 494871838 139 TLGIGFppfwLALMLIILFSVKLGVlpVSGYGDSFLDKA------AHLVLPSLTIALSLSAVLTRSL------------- 199
Cdd:COG1173   81 SLLVGL----LAVLIALVIGVLLGL--LAGYFGGWVDAVlmrlvdVLLAFPSLLLAIALVAVLGPGLlnvilalgltgwp 154

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 494871838 200 ------RAAMTVELQSDLATAARARGMPESIVFWRHVLPNSLVPTINLLAVNIGWLI 250
Cdd:COG1173  155 gyarlvRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAI 211
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 214-242 3.99e-04

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 41.68  E-value: 3.99e-04
                         10        20
                 ....*....|....*....|....*....
gi 494871838 214 AARARGMPESIVFWRHVLPNSLVPTINLL 242
Cdd:COG4239  237 AARALGVSDRRIMFRHILPNAMVATLTFL 265
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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