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Conserved domains on  [gi|495106581|ref|WP_007831404|]
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MULTISPECIES: adenylate kinase [Phocaeicola]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11478412)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

CATH:  3.40.50.300
EC:  2.7.4.-
Gene Ontology:  GO:0050145|GO:0016310|GO:0046872
PubMed:  2841070
SCOP:  3002021

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 2-189 1.87e-100

adenylate kinase; Reviewed


:

Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 288.59  E-value: 1.87e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   2 LNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKG 81
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  82 VIFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKR---------------------------GQESGR 134
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQR 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 495106581 135 ADDNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAIFADIVATVEKL 189
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGKL 215
 
Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 2-189 1.87e-100

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 288.59  E-value: 1.87e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   2 LNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKG 81
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  82 VIFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKR---------------------------GQESGR 134
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQR 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 495106581 135 ADDNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAIFADIVATVEKL 189
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGKL 215
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 3-184 1.49e-93

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 271.23  E-value: 1.49e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   3 NIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGV 82
Cdd:COG0563    2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANGF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  83 IFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKR---------------------------GQESGRA 135
Cdd:COG0563   82 ILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRrvcpncgatyhvkfnppkvegvcdkcgGELVQRA 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 495106581 136 DDNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAIFADIVA 184
Cdd:COG0563  162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILA 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 3-178 9.33e-81

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 237.91  E-value: 9.33e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   3 NIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGV 82
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  83 IFDGFPRTIAQAEALKKMLAErGQEVSVMLDLDVPEEELMTRLIKRGQE-------------------SGRADDNEETIK 143
Cdd:cd01428   81 ILDGFPRTVDQAEALDELLDE-GIKPDKVIELDVPDEVLIERILGRRICpvsgrvyhlgkddvtgeplSQRSDDNEETIK 159

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 495106581 144 KRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAI 178
Cdd:cd01428  160 KRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 3-184 9.51e-76

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 225.96  E-value: 9.51e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581    3 NIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKE-SKG 81
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDnENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   82 VIFDGFPRTIAQAEALKKMLAERgqeVSVMLDLDVPEEELMTRLIKRGQESG---------------------------R 134
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLEEP---IDAVIELDVPDEELVERLSGRRICPScgrvyhlkfnppkvpgcddctgellvqR 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 495106581  135 ADDNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAIFADIVA 184
Cdd:TIGR01351 158 EDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILE 207
ADK pfam00406
Adenylate kinase;
6-163 5.38e-70

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 210.63  E-value: 5.38e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581    6 IFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGVIFD 85
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   86 GFPRTIAQAEALKKMLaERGQEVSVMLDLDVPEEELMTRLIKRG---------------------------QESGRADDN 138
Cdd:pfam00406  81 GFPRTVPQAEALEELL-ERGIKLDYVIEFDVPDEVLVERLTGRRihpnsgrsyhlefnppkvpgkddvtgePLVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
gi 495106581  139 EETIKKRLVVYHSQTAPLIDWYKNE 163
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
 
Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 2-189 1.87e-100

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 288.59  E-value: 1.87e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   2 LNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKG 81
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  82 VIFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKR---------------------------GQESGR 134
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQR 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 495106581 135 ADDNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAIFADIVATVEKL 189
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGKL 215
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 3-184 1.49e-93

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 271.23  E-value: 1.49e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   3 NIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGV 82
Cdd:COG0563    2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANGF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  83 IFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKR---------------------------GQESGRA 135
Cdd:COG0563   82 ILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRrvcpncgatyhvkfnppkvegvcdkcgGELVQRA 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 495106581 136 DDNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAIFADIVA 184
Cdd:COG0563  162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILA 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 3-178 9.33e-81

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 237.91  E-value: 9.33e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   3 NIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGV 82
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  83 IFDGFPRTIAQAEALKKMLAErGQEVSVMLDLDVPEEELMTRLIKRGQE-------------------SGRADDNEETIK 143
Cdd:cd01428   81 ILDGFPRTVDQAEALDELLDE-GIKPDKVIELDVPDEVLIERILGRRICpvsgrvyhlgkddvtgeplSQRSDDNEETIK 159

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 495106581 144 KRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAI 178
Cdd:cd01428  160 KRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 3-184 9.51e-76

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 225.96  E-value: 9.51e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581    3 NIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKE-SKG 81
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDnENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   82 VIFDGFPRTIAQAEALKKMLAERgqeVSVMLDLDVPEEELMTRLIKRGQESG---------------------------R 134
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLEEP---IDAVIELDVPDEELVERLSGRRICPScgrvyhlkfnppkvpgcddctgellvqR 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 495106581  135 ADDNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAIFADIVA 184
Cdd:TIGR01351 158 EDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILE 207
ADK pfam00406
Adenylate kinase;
6-163 5.38e-70

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 210.63  E-value: 5.38e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581    6 IFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGVIFD 85
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   86 GFPRTIAQAEALKKMLaERGQEVSVMLDLDVPEEELMTRLIKRG---------------------------QESGRADDN 138
Cdd:pfam00406  81 GFPRTVPQAEALEELL-ERGIKLDYVIEFDVPDEVLVERLTGRRihpnsgrsyhlefnppkvpgkddvtgePLVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
gi 495106581  139 EETIKKRLVVYHSQTAPLIDWYKNE 163
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
PRK14532 PRK14532
adenylate kinase; Provisional
 2-187 5.93e-70

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 210.45  E-value: 5.93e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   2 LNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKG 81
Cdd:PRK14532   1 MNLILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAEAAGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  82 VIFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKRGQESGRADDNEETIKKRLVVYHSQTAPLIDWYK 161
Cdd:PRK14532  81 AIFDGFPRTVAQAEALDKMLASRGQKIDVVIRLKVDDEALIERIVKRFEEQGRPDDNPEVFVTRLDAYNAQTAPLLPYYA 160

                        170       180
                 ....*....|....*....|....*.
gi 495106581 162 NEGKYQHIHGLGTMDAIFADIVATVE 187
Cdd:PRK14532 161 GQGKLTEVDGMGSIEAVAASIDAALE 186
PRK14527 PRK14527
adenylate kinase; Provisional
 4-186 2.87e-68

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 206.56  E-value: 2.87e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   4 IVIF-GAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKgV 82
Cdd:PRK14527   8 VVIFlGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVR-V 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  83 IFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKRGQESGRADDNEETIKKRLVVYHSQTAPLIDWYKN 162
Cdd:PRK14527  87 IFDGFPRTLAQAEALDRLLEELGARLLAVVLLEVPDEELIRRIVERARQEGRSDDNEETVRRRQQVYREQTQPLVDYYEA 166

                        170       180
                 ....*....|....*....|....
gi 495106581 163 EGKYQHIHGLGTMDAIFADIVATV 186
Cdd:PRK14527 167 RGHLKRVDGLGTPDEVYARILKAL 190
adk PRK02496
adenylate kinase; Provisional
 1-186 1.56e-66

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 201.90  E-value: 1.56e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   1 MLNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESK 80
Cdd:PRK02496   1 MTRLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAAN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  81 GVIFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKRgqesGRADDNEETIKKRLVVYHSQTAPLIDWY 160
Cdd:PRK02496  81 GWILDGFPRKVTQAAFLDELLQEIGQSGERVVNLDVPDDVVVERLLAR----GRKDDTEEVIRRRLEVYREQTAPLIDYY 156

                        170       180
                 ....*....|....*....|....*.
gi 495106581 161 KNEGKYQHIHGLGTMDAIFADIVATV 186
Cdd:PRK02496 157 RDRQKLLTIDGNQSVEAVTTELKAAL 182
PRK14528 PRK14528
adenylate kinase; Provisional
 1-186 3.67e-60

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 185.60  E-value: 3.67e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   1 MLNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESK 80
Cdd:PRK14528   1 MKNIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  81 GVIFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKRGQESGRADDNEETIKKRLVVYHSQTAPLIDWY 160
Cdd:PRK14528  81 GFLLDGFPRTVEQADALDALLKNEGKSIDKAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYNKKTLPLLDFY 160

                        170       180
                 ....*....|....*....|....*.
gi 495106581 161 KNEGKYQHIHGLGTMDAIFADIVATV 186
Cdd:PRK14528 161 AAQKKLSQVNGVGSLEEVTSLIQKEL 186
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 4-189 4.55e-56

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 175.39  E-value: 4.55e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581    4 IVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILA-STLDSFKESKGV 82
Cdd:TIGR01360   6 IFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKdAMVAALGTSKGF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   83 IFDGFPRTIAQAEALKKmlaeRGQEVSVMLDLDVPEEELMTRLIKRGQESGRADDNEETIKKRLVVYHSQTAPLIDWYKN 162
Cdd:TIGR01360  86 LIDGYPREVKQGEEFER----RIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYET 161

                         170       180
                  ....*....|....*....|....*..
gi 495106581  163 EGKYQHIHGLGTMDAIFADIVATVEKL 189
Cdd:TIGR01360 162 KGKLRKINAEGTVDDVFLQVCTAIDKL 188
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 5-182 8.85e-55

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 171.79  E-value: 8.85e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581    5 VIF--GAPGSGKGTQSERIVEKFGINHISTGDVLRAEIK-KGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKG 81
Cdd:TIGR01359   1 VVFvlGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKrEGSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGSSKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   82 VIFDGFPRTIAQAEALKKMLAERgQEVSVMLDLDVPEEELMTRLIKRGQESGRADDNEETIKKRLVVYHSQTAPLIDWYK 161
Cdd:TIGR01359  81 FLIDGFPRNEENLEAWEKLMDNK-VNFKFVLFFDCPEETMIKRLLKRGQTSGRVDDNIETLKKRFRTYNEETLPIIEHFE 159

                         170       180
                  ....*....|....*....|.
gi 495106581  162 NEGKYQHIHGLGTMDAIFADI 182
Cdd:TIGR01359 160 NKGKVKEINAEGSVEEVFEDV 180
PRK14531 PRK14531
adenylate kinase; Provisional
 1-186 1.87e-54

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 171.15  E-value: 1.87e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   1 MLNIVIF-GAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFkES 79
Cdd:PRK14531   1 MKQRLLFlGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKAL-NS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  80 KGVIFDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKRgqesGRADDNEETIKKRLVVYHSQTAPLIDW 159
Cdd:PRK14531  80 GGWLLDGFPRTVAQAEALEPLLEELKQPIEAVVLLELDDAVLIERLLAR----GRADDNEAVIRNRLEVYREKTAPLIDH 155

                        170       180
                 ....*....|....*....|....*..
gi 495106581 160 YKNEGKYQHIHGLGTMDAIFADIVATV 186
Cdd:PRK14531 156 YRQRGLLQSVEAQGSIEAITERIEKVL 182
PRK14530 PRK14530
adenylate kinase; Provisional
 3-187 1.31e-46

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 152.25  E-value: 1.31e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   3 NIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKK-----GTELGkTAKGYIDQGQLLPDELIIDILASTLDSfk 77
Cdd:PRK14530   5 RILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRANKQMdisdmDTEYD-TPGEYMDAGELVPDAVVNEIVEEALSD-- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  78 eSKGVIFDGFPRTIAQAEALKKMlaergQEVSVMLDLDVPEEELMTRLIKR---------------------------GQ 130
Cdd:PRK14530  82 -ADGFVLDGYPRNLEQAEYLESI-----TDLDVVLYLDVSEEELVDRLTGRrvcpdcganyhvefnqpeeegvcdecgGE 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495106581 131 ESGRADDNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAIFADIVATVE 187
Cdd:PRK14530 156 LIQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQDAID 212
PRK13808 PRK13808
adenylate kinase; Provisional
 4-182 5.37e-45

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 151.58  E-value: 5.37e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   4 IVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGVI 83
Cdd:PRK13808   3 LILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANGFI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  84 FDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTR-------LIKRGQESgRADDNEETIKKRLVVYHSQTAPL 156
Cdd:PRK13808  83 LDGFPRTVPQAEALDALLKDKQLKLDAVVELRVNEGALLARvetrvaeMRARGEEV-RADDTPEVLAKRLASYRAQTEPL 161

                        170       180
                 ....*....|....*....|....*.
gi 495106581 157 IDWYKNEGKYQHIHGLGTMDAIFADI 182
Cdd:PRK13808 162 VHYYSEKRKLLTVDGMMTIDEVTREI 187
PLN02200 PLN02200
adenylate kinase family protein
 6-179 3.97e-43

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 143.88  E-value: 3.97e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   6 IFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGVIfD 85
Cdd:PLN02200  48 VLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSDNNKFLI-D 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  86 GFPRTIAQAEALKKMLaerGQEVSVMLDLDVPEEELMTRLIKRGQesGRADDNEETIKKRLVVYHSQTAPLIDWYKNEGK 165
Cdd:PLN02200 127 GFPRTEENRIAFERII---GAEPNVVLFFDCPEEEMVKRVLNRNQ--GRVDDNIDTIKKRLKVFNALNLPVIDYYSKKGK 201

                        170
                 ....*....|....
gi 495106581 166 YQHIHGLGTMDAIF 179
Cdd:PLN02200 202 LYTINAVGTVDEIF 215
AAA_17 pfam13207
AAA domain;
7-143 2.42e-41

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 135.83  E-value: 2.42e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581    7 FGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTelGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGVIFDG 86
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERIAEEAGEGGVIVDG 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 495106581   87 FPRTIAQAEALKKMLAERGQE--VSVMLDLDVPEEELMTRLIKRgQESGRADDNEETIK 143
Cdd:pfam13207  79 HPRIKTPAGYLPGLPVEVLRElkPDAIILLEADPEEILERRLKD-RTRGRDDDSEEEIR 136
PLN02674 PLN02674
adenylate kinase
 4-170 1.18e-38

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 132.70  E-value: 1.18e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   4 IVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKGVI 83
Cdd:PLN02674  34 LILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPSCQKGFI 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  84 FDGFPRTIAQAEALKKMLAERGQEVSVMLDLDVPEEELMTRLIKR--GQESGRA-------------------------D 136
Cdd:PLN02674 114 LDGFPRTVVQAQKLDEMLAKQGAKIDKVLNFAIDDAILEERITGRwiHPSSGRTyhtkfappkvpgvddvtgepliqrkD 193

                        170       180       190
                 ....*....|....*....|....*....|....
gi 495106581 137 DNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIH 170
Cdd:PLN02674 194 DTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLH 227
PLN02459 PLN02459
probable adenylate kinase
 2-165 9.35e-38

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 130.74  E-value: 9.35e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   2 LNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKE--S 79
Cdd:PLN02459  30 VNWVFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAGEEegE 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  80 KGVIFDGFPRTIAQAEALKKMlAERGQEVSVMLDLDVPEEELMTRL-------------IKRGQESG------------- 133
Cdd:PLN02459 110 SGFILDGFPRTVRQAEILEGV-TDIDLVVNLKLREEVLVEKCLGRRicsecgknfnvadIDLKGEDGrpgivmppllppp 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 495106581 134 --------RADDNEETIKKRLVVYHSQTAPLIDWYKNEGK 165
Cdd:PLN02459 189 ecasklitRADDTEEVVKARLRVYKEESQPVEDFYRKRGK 228
PLN02842 PLN02842
nucleotide kinase
 5-162 4.99e-37

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 133.83  E-value: 4.99e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   5 VIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILAS--TLDSFKEsKGV 82
Cdd:PLN02842   1 MISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGrlSREDAKE-KGW 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  83 IFDGFPRTIAQAEALKKmLAERGQevsVMLDLDVPEEELMTRLIKR--GQESG---------------------RADDNE 139
Cdd:PLN02842  80 LLDGYPRSFAQAQSLEK-LKIRPD---IFILLDVPDEILIDRCVGRrlDPVTGkiyhiknfppeseeikarlitRPDDTE 155

                        170       180
                 ....*....|....*....|...
gi 495106581 140 ETIKKRLVVYHSQTAPLIDWYKN 162
Cdd:PLN02842 156 EKVKARLQIYKKNAEAILSTYSD 178
PRK14529 PRK14529
adenylate kinase; Provisional
 2-184 1.01e-35

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 124.45  E-value: 1.01e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   2 LNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSfKESKG 81
Cdd:PRK14529   1 MNILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQ-DGKNG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  82 VIFDGFPRTIAQAEALKKMLAERGQE----VSVMLDLDVPEEELMTR----------------LIK---------RGQES 132
Cdd:PRK14529  80 WLLDGFPRNKVQAEKLWEALQKEGMKldyvIEILLPREVAKNRIMGRrlckndnnhpnnifidAIKpdgdvcrvcGGELS 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495106581 133 GRADD-NEETIKKRLVVYHSQ---TAPLIDWYKNEG-----KYQHIHGLGTMDAIFADIVA 184
Cdd:PRK14529 160 TRADDqDEEAINKRHDIYYDTetgTLAAAYFFKDLAakgstKYIELDGEGSIDEIKETLLK 220
PRK14526 PRK14526
adenylate kinase; Provisional
 2-188 2.09e-33

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 118.03  E-value: 2.09e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   2 LNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDILASTLDSFKESKG 81
Cdd:PRK14526   1 MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNNDN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  82 VIFDGFPRTIAQAEALKKMLaERGQEVSVMLDldvpEEELMTRLIKR---------------------------GQESGR 134
Cdd:PRK14526  81 FILDGFPRNINQAKALDKFL-PNIKIINFLID----EELLIKRLSGRrickscnnifniytlptkekgicdvckGDLYQR 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 495106581 135 ADDNEETIKKRLVVYHSQTAPLIDWYKNEGKYQHIHGLGTMDAIFADIVATVEK 188
Cdd:PRK14526 156 KDDKEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEVKKKLIEIISK 209
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 2-164 4.18e-33

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 117.98  E-value: 4.18e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   2 LNIVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEIKKGTELGKTAKGYIDQGQLLPDELIIDI----LASTLDsfK 77
Cdd:PTZ00088   7 LKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIvkdeIAKVTD--D 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581  78 ESKGVIFDGFPRTIAQAEALKKMlaergQEVSVMLDLDVPEEELMTRLIKR----------------------------- 128
Cdd:PTZ00088  85 CFKGFILDGFPRNLKQCKELGKI-----TNIDLFVNIYLPRNILIKKLLGRricntcnrnfniahirsdpydmppilppa 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 495106581 129 --------GQESGRADDNEETIKKRLVVYHSQTAPLIDWYKNEG 164
Cdd:PTZ00088 160 dcegckgnPKLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNEN 203
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
4-146 3.99e-12

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 61.08  E-value: 3.99e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   4 IVIFGAPGSGKGTQSERIVEKFGINHISTgDVLRAEIkKGTELGKTAkGYIDQGQLLPDEL---IIDILASTLDsfkesk 80
Cdd:COG0645    2 ILVCGLPGSGKSTLARALAERLGAVRLRS-DVVRKRL-FGAGLAPLE-RSPEATARTYARLlalARELLAAGRS------ 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495106581  81 gVIFD-GFPRTiAQAEALKKMLAERGQEVsVMLDLDVPEEELMTRLIKRGQESGRADDNEETIKKRL 146
Cdd:COG0645   73 -VILDaTFLRR-AQREAFRALAEEAGAPF-VLIWLDAPEEVLRERLEARNAEGGDSDATWEVLERQL 136
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 4-144 8.01e-10

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 54.62  E-value: 8.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581    4 IVIFGAPGSGKGTQSERIVEKFGINHISTgDVLRAEIKKgtELGKTAKGYIDQGQLLPDELiIDILASTLdsfKESKGVI 83
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLSS-DDERKRLFG--EGRPSISYYTDATDRTYERL-HELARIAL---RAGRPVI 74

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495106581   84 FDGfprTIAQAEALKKMLA---ERGQEVSVmLDLDVPEEELMTRLIKRGQESGRADD-NEETIKK 144
Cdd:pfam13671  75 LDA---TNLRRDERARLLAlarEYGVPVRI-VVFEAPEEVLRERLAARARAGGDPSDvPEEVLDR 135
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
1-145 8.90e-10

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 55.34  E-value: 8.90e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   1 MLNIVIFGAPGSGKGTQSeRIVEKFGINHISTGDVLRAEIKK-GTELGKTAKGYIdqGQLLPDELIIDILA-STLDSFKE 78
Cdd:PRK01184   1 MKIIGVVGMPGSGKGEFS-KIAREMGIPVVVMGDVIREEVKKrGLEPTDENIGKV--AIDLRKELGMDAVAkRTVPKIRE 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495106581  79 --SKGVIFDGFpRTIAQAEALKKMLAERGQEVSVmldlDVPEEELMTRLIKRgqesGRADDNE--ETIKKR 145
Cdd:PRK01184  78 kgDEVVVIDGV-RGDAEVEYFRKEFPEDFILIAI----HAPPEVRFERLKKR----GRSDDPKswEELEER 139
AAA_18 pfam13238
AAA domain;
4-140 1.82e-07

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 47.81  E-value: 1.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581    4 IVIFGAPGSGKGTQSERIVEKFGInhistGDVLRAEIKKGtelgktaKGYIDQGQLLPDELIIDI--LASTLDSFKES-- 79
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLGF-----GDNVRDLALEN-------GLVLGDDPETRESKRLDEdkLDRLLDLLEENaa 68

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495106581   80 ----KGVIFDGFPrtiAQAEalkkmlaERGQEVSVMLDLDVPEEELMTRLIKRGQESGRADDNEE 140
Cdd:pfam13238  69 leegGNLIIDGHL---AELE-------PERAKDLVGIVLRASPEELLERLEKRGYEEAKIKENEE 123
PRK04182 PRK04182
cytidylate kinase; Provisional
 4-37 8.47e-06

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 44.03  E-value: 8.47e-06
                         10        20        30
                 ....*....|....*....|....*....|....
gi 495106581   4 IVIFGAPGSGKGTQSERIVEKFGINHISTGDVLR 37
Cdd:PRK04182   3 ITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFR 36
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 4-39 2.58e-04

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 39.39  E-value: 2.58e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 495106581   4 IVIFGAPGSGKGTQSERIVEKFGINHISTGDvLRAE 39
Cdd:cd02020    2 IAIDGPAGSGKSTVAKLLAKKLGLPYLDTGG-IRTE 36
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 4-37 3.54e-04

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 39.33  E-value: 3.54e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 495106581    4 IVIFGAPGSGKGTQSERIVEKFGINHISTGDVLR 37
Cdd:TIGR02173   3 ITISGPPGSGKTTVAKILAEKLSLKLISAGDIFR 36
PRK08118 PRK08118
DNA topology modulation protein;
1-106 1.13e-03

DNA topology modulation protein;


Pssm-ID: 181235  Cd Length: 167  Bit Score: 38.05  E-value: 1.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   1 MLNIVIFGAPGSGKGTQSERIVEKFGINHIStgdvLRAEI-KKGTELGKTAKGYIDQGQLLP-DELIID-ILASTLD-SF 76
Cdd:PRK08118   1 MKKIILIGSGGSGKSTLARQLGEKLNIPVHH----LDALFwKPNWEGVPKEEQITVQNELVKeDEWIIDgNYGGTMDiRL 76

                         90       100       110
                 ....*....|....*....|....*....|
gi 495106581  77 KESKGVIFDGFPRTIAQAEALKKMLAERGQ 106
Cdd:PRK08118  77 NAADTIIFLDIPRTICLYRAFKRRVQYRGK 106
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 4-128 1.49e-03

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 37.23  E-value: 1.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   4 IVIFGAPGSGKGTQSERIVEKFGINHIStGDVLR--AEIKKGTelgktakgyidQGQLLPDELIIDIL-----ASTLDSF 76
Cdd:cd02021    2 IVVMGVSGSGKSTVGKALAERLGAPFID-GDDLHppANIAKMA-----------AGIPLNDEDRWPWLqaltdALLAKLA 69

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495106581  77 KESKGVIFDgfprtiaqAEALKK----MLAERGQEVSVM-LDLDVPEEELMTRLIKR 128
Cdd:cd02021   70 SAGEGVVVA--------CSALKRiyrdILRGGAANPRVRfVHLDGPREVLAERLAAR 118
COG4639 COG4639
Predicted kinase [General function prediction only];
4-128 1.51e-03

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 37.12  E-value: 1.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   4 IVIFGAPGSGKGTQSERIVEKFGInhISTgDVLRAEIkKGTElgktakgyIDQGqllPDELIIDILASTLDSF-KESKGV 82
Cdd:COG4639    5 VVLIGLPGSGKSTFARRLFAPTEV--VSS-DDIRALL-GGDE--------NDQS---AWGDVFQLAHEIARARlRAGRLT 69

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 495106581  83 IFDGfprTIAQAEA---LKKMLAERGQEVsVMLDLDVPEEELMTRLIKR 128
Cdd:COG4639   70 VVDA---TNLQREArrrLLALARAYGALV-VAVVLDVPLEVCLARNAAR 114
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
4-83 7.55e-03

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 35.56  E-value: 7.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495106581   4 IVIFGAPGSGKGTQSERIVEKFGINHISTGDVLRAEikkgtELGKtakgYIDQGQllpDELIIDI--LASTLDSFKESKG 81
Cdd:COG1936    3 IAITGTPGTGKTTVAKLLAERLGLEVIHLNDLVKEE-----GLYT----EVDEER---DSLVVDEdaLAEELEELKEGDV 70


                 ..
gi 495106581  82 VI 83
Cdd:COG1936   71 II 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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