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Conserved domains on  [gi|495111615|ref|WP_007836435|]
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MULTISPECIES: DNA polymerase III subunit delta [Phocaeicola]

Protein Classification

ATP-binding protein( domain architecture ID 11457986)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain, similar to magnesium-chelatase subunit ChlI and RuvB-like helicase 1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
3-369 3.03e-102

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


:

Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 305.58  E-value: 3.03e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVF 82
Cdd:COG2812    9 FDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEID 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 PvikkkagkdtvcddfiadwrnfvlqnpyfnlnhwlkemgaenQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:COG2812   89 A------------------------------------------EASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHML 126
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ---TKYGLQ--PEDADDIAHRSE 237
Cdd:COG2812  127 TTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLPPEEIAEHLAkiaEREGIEiePEALALIARAAD 206
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 238 GNFLKALEtihLSEENKLF-----FELFINLMRLSYQRKIREMKQWSDAVASMGRErQKNFLAYCQRMIRENFIYNFHQR 312
Cdd:COG2812  207 GSMRDALS---LLDQAIAFglldrRELLLDLLEALLAGDVAALLALAEELAKRGRD-LKRFLDDLLSLLRDLLLLKLGPD 282
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495111615 313 DLVYMNPEEQNFSTRFAPFVNERNVMGIMDELSEAQLHIGQNVNPKMVFFDFSLKMI 369
Cdd:COG2812  283 AELLVNEDERERLQELARRLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLA 339
 
Name Accession Description Interval E-value
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
3-369 3.03e-102

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 305.58  E-value: 3.03e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVF 82
Cdd:COG2812    9 FDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEID 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 PvikkkagkdtvcddfiadwrnfvlqnpyfnlnhwlkemgaenQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:COG2812   89 A------------------------------------------EASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHML 126
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ---TKYGLQ--PEDADDIAHRSE 237
Cdd:COG2812  127 TTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLPPEEIAEHLAkiaEREGIEiePEALALIARAAD 206
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 238 GNFLKALEtihLSEENKLF-----FELFINLMRLSYQRKIREMKQWSDAVASMGRErQKNFLAYCQRMIRENFIYNFHQR 312
Cdd:COG2812  207 GSMRDALS---LLDQAIAFglldrRELLLDLLEALLAGDVAALLALAEELAKRGRD-LKRFLDDLLSLLRDLLLLKLGPD 282
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495111615 313 DLVYMNPEEQNFSTRFAPFVNERNVMGIMDELSEAQLHIGQNVNPKMVFFDFSLKMI 369
Cdd:COG2812  283 AELLVNEDERERLQELARRLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLA 339
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
13-243 3.20e-54

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 177.05  E-value: 3.20e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   13 KQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVFPVikkkagkd 92
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPE-------- 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   93 tvcddfiadwrnfvlqnpyfnlnhwlkemgaenqQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNVECSNKLLK 172
Cdd:TIGR00678  73 ----------------------------------GQSIKVDQVRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLK 118
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495111615  173 LLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKyGLQPEDADDIAHRSEGNFLKA 243
Cdd:TIGR00678 119 TLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALLQWLIRQ-GISEEAAELLLALAGGSPGRA 188
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
8-206 6.43e-46

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 154.68  E-value: 6.43e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615    8 GQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVFPvikk 87
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEP---- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   88 kagkdtvcddfiadwrnfvlqnpyfnlnhwlkemgaenQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNVECS 167
Cdd:pfam13177  77 --------------------------------------EGQSIKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAA 118
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 495111615  168 NKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNI 206
Cdd:pfam13177 119 NSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRF 157
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
5-244 4.87e-28

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 112.81  E-value: 4.87e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   5 DVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKfnklIHPDlHfvfPV 84
Cdd:PRK07471  20 ALFGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARFLLATPPPGGDGAVPPPTSLA----IDPD-H---PV 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  85 IKKKAGKdtvcddfiADWRNFVLQNPYfnlnhwlKEMGAEnQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNV 164
Cdd:PRK07471  92 ARRIAAG--------AHGGLLTLERSW-------NEKGKR-LRTVITVDEVRELISFFGLTAAEGGWRVVIVDTADEMNA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 165 ECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQPEDA-DDIAHRSEGNFLKA 243
Cdd:PRK07471 156 NAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVIDALAAAGPDLPDDPrAALAALAEGSVGRA 235

                 .
gi 495111615 244 L 244
Cdd:PRK07471 236 L 236
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
3-47 6.30e-06

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 46.07  E-value: 6.30e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495111615   3 FKDVIGQEEAKQRLiAEVKE------------GRIPHAQLICGPEGTGKLPLAIAYA 47
Cdd:cd19501    3 FKDVAGCEEAKEEL-KEVVEflknpekftklgAKIPKGVLLVGPPGTGKTLLAKAVA 58
 
Name Accession Description Interval E-value
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
3-369 3.03e-102

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 305.58  E-value: 3.03e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVF 82
Cdd:COG2812    9 FDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEID 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 PvikkkagkdtvcddfiadwrnfvlqnpyfnlnhwlkemgaenQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:COG2812   89 A------------------------------------------EASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHML 126
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ---TKYGLQ--PEDADDIAHRSE 237
Cdd:COG2812  127 TTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLPPEEIAEHLAkiaEREGIEiePEALALIARAAD 206
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 238 GNFLKALEtihLSEENKLF-----FELFINLMRLSYQRKIREMKQWSDAVASMGRErQKNFLAYCQRMIRENFIYNFHQR 312
Cdd:COG2812  207 GSMRDALS---LLDQAIAFglldrRELLLDLLEALLAGDVAALLALAEELAKRGRD-LKRFLDDLLSLLRDLLLLKLGPD 282
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495111615 313 DLVYMNPEEQNFSTRFAPFVNERNVMGIMDELSEAQLHIGQNVNPKMVFFDFSLKMI 369
Cdd:COG2812  283 AELLVNEDERERLQELARRLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLA 339
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
9-368 7.49e-59

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 192.50  E-value: 7.49e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   9 QEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPtCVKFNKLIHPDLHFVFPVIKKK 88
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELNPEEKSD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  89 A-GKDTVcddfiadwRnfvlqnpyfnlnhwlkemgaenqqaqifvkesdEIVRKLSLKSSQGGYKIMIIWLPEKMNVECS 167
Cdd:COG0470   80 QiGIDQI--------R---------------------------------ELGEFLSLTPLEGGRKVVIIDEADAMNEAAA 118
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 168 NKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKyGLQPEDADDIAHRSEGNFLKALETI 247
Cdd:COG0470  119 NALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRPPSEEEALAWLREE-GVDEDALEAILRLAGGDPRAAINLL 197
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 248 HLSEENKLFFELFINLmrLSYQRKIREMKQWSDAVASmgrerqkNFLAYCQRMIRENFIYNFHQRDLVymnpeeqnfstr 327
Cdd:COG0470  198 QALAGRKELLEDLAAL--LSRDRALELLDALLKAEAL-------ELLDWLLKWLLDNLPLEYAGEDLA------------ 256
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 495111615 328 fapfvnernvmGIMDELSEAQLHIGQNVNPKMVFFDFSLKM 368
Cdd:COG0470  257 -----------RAYEALSEADRRLGRYANDRLLLEALLAKL 286
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
13-243 3.20e-54

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 177.05  E-value: 3.20e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   13 KQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVFPVikkkagkd 92
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPE-------- 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   93 tvcddfiadwrnfvlqnpyfnlnhwlkemgaenqQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNVECSNKLLK 172
Cdd:TIGR00678  73 ----------------------------------GQSIKVDQVRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLK 118
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495111615  173 LLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKyGLQPEDADDIAHRSEGNFLKA 243
Cdd:TIGR00678 119 TLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALLQWLIRQ-GISEEAAELLLALAGGSPGRA 188
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
8-206 6.43e-46

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 154.68  E-value: 6.43e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615    8 GQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVFPvikk 87
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEP---- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   88 kagkdtvcddfiadwrnfvlqnpyfnlnhwlkemgaenQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNVECS 167
Cdd:pfam13177  77 --------------------------------------EGQSIKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAA 118
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 495111615  168 NKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNI 206
Cdd:pfam13177 119 NSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRF 157
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-369 2.60e-29

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 116.13  E-value: 2.60e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615    3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHfvf 82
Cdd:TIGR02397  13 FEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEINSGSSLDVI--- 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   83 pvikkkagkdtvcddfiadwrnfvlqnpyfnlnhwlkEM-GAENqqaqIFVKESDEIVRKLSLKSSQGGYKIMIIwlpek 161
Cdd:TIGR02397  90 -------------------------------------EIdAASN----NGVDDIREILDNVKYAPSSGKYKVYII----- 123
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  162 mnVECS-------NKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ---TKYGLQPEDA-- 229
Cdd:TIGR02397 124 --DEVHmlsksafNALLKTLEEPPEHVVFILATTEPHKIPATILSRCQRFDFKRIPLEDIVERLKkilDKEGIKIEDEal 201
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  230 DDIAHRSEGNF---LKALETIHLSEENKLFFELFINLMRLSYQRKIREMkqwsdaVASMGRERQKNFLAYCQRMIRENF- 305
Cdd:TIGR02397 202 ELIARAADGSLrdaLSLLDQLISFGNGKITYEDVNELLGLVDDEKLIEL------LEAILNKDTAEALKILDEILESGVd 275
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  306 IYNFHQ------RDLV----------YMNPEEQNFSTRFAPFVNERNVMGIMDELSEAQLHIGQNVNPKMVFFDFSLKMI 369
Cdd:TIGR02397 276 PEKFLEdlieilRDLLlikktpsnllAVLESEQEFLKELALKLSLEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
5-244 4.87e-28

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 112.81  E-value: 4.87e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   5 DVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKfnklIHPDlHfvfPV 84
Cdd:PRK07471  20 ALFGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARFLLATPPPGGDGAVPPPTSLA----IDPD-H---PV 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  85 IKKKAGKdtvcddfiADWRNFVLQNPYfnlnhwlKEMGAEnQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNV 164
Cdd:PRK07471  92 ARRIAAG--------AHGGLLTLERSW-------NEKGKR-LRTVITVDEVRELISFFGLTAAEGGWRVVIVDTADEMNA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 165 ECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQPEDA-DDIAHRSEGNFLKA 243
Cdd:PRK07471 156 NAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVIDALAAAGPDLPDDPrAALAALAEGSVGRA 235

                 .
gi 495111615 244 L 244
Cdd:PRK07471 236 L 236
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
9-357 7.13e-28

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 111.72  E-value: 7.13e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   9 QEEAKQRLIAEvkeGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVFPVIKKK 88
Cdd:PRK05707   8 QQSLWQQLAGR---GRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNFVLEPEEADK 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  89 AgkdtvcddfiadwrnfvlqnpyfnlnhwlkemgaenqqaqIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNVECSN 168
Cdd:PRK05707  85 T----------------------------------------IKVDQVRELVSFVVQTAQLGGRKVVLIEPAEAMNRNAAN 124
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 169 KLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYG-LQPEDADDIAHRSEGNFLKALEti 247
Cdd:PRK05707 125 ALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESLQWLQQALPeSDERERIELLTLAGGSPLRALQ-- 202
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 248 hLSEENKLFF--ELFINLMRLSYQRKiremkqwsdAVASMGRERQKN--------FLAYCQRMIR------ENFIYNFHQ 311
Cdd:PRK05707 203 -LHEQGVREQraRVLDGVKKLLKQQQ---------SASQLAESWLKVpllllfdwFCDWAHDILRyqltqdEEGLGLADM 272
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 495111615 312 RDLVymnpeeQNFSTRFAPfvneRNVMGIMDELSEA-QLHIGQ-NVNP 357
Cdd:PRK05707 273 RKVL------QYLAQKSPQ----AKVLALQDWLLEQrQKVLGKaNLNR 310
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
9-204 8.13e-26

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 106.38  E-value: 8.13e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   9 QEEAKQRLIAevKEGRIPHAQLICGPEGTGKLPLAIAYARYICCEN-RGEQDACGICPTCVKFNKLIHPDLHFVFPVIKK 87
Cdd:PRK06964   6 QTDDWNRLQA--LRARLPHALLLHGQAGIGKLDFAQHLAQGLLCETpQPDGEPCGTCAACNWFAQGNHPDYRIVRPEALA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  88 KAGKDTVCDDFIADwrnfvlqnpyfnlnhwlKEMGAENQQAqifvkESDEI----VRKLS----LKSSQGGYKIMIIWLP 159
Cdd:PRK06964  84 AEAPGAADEAKEAD-----------------ADEGGKKTKA-----PSKEIkieqVRALLdfcgVGTHRGGARVVVLYPA 141
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 495111615 160 EKMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRF 204
Cdd:PRK06964 142 EALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLPTILSRCRQF 186
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
10-310 1.15e-24

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 102.64  E-value: 1.15e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  10 EEAKQRLIAEVKEgRIPHAQLICGPEGTGKLPLAIAYARYICCEN-RGEQDACGICPTCVKFNKLIHPDLHFVFPVIKKK 88
Cdd:PRK08699   6 HQEQWRQIAEHWE-RRPNAWLFAGKKGIGKTAFARFAAQALLCETpAPGHKPCGECMSCHLFGQGSHPDFYEITPLSDEP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  89 agkdtvcddfiadwrnfvlqnpyfnlnhwlkEMGaeNQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNVECSN 168
Cdd:PRK08699  85 -------------------------------ENG--RKLLQIKIDAVREIIDNVYLTSVRGGLRVILIHPAESMNLQAAN 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 169 KLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNI--------------HGIKEPEI-------SKVLQTKYGLQPE 227
Cdd:PRK08699 132 SLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLpapsheealaylreRGVAEPEErlafhsgAPLFDEEPELRAL 211
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 228 DADDIAHRSEGNFLKALETIHLSEENKLFFELFI--------NLMRLSYQRKIREMKQWSDAVASM-GRERQKNFLAyCQ 298
Cdd:PRK08699 212 RIKLLDILAEPRLLKILDYAALFDKEKLPLAVFVgwmqkwlvDLGLCLQHMKPVYYPAYEDRLLQTaSGFRPRNVFA-AE 290
                        330
                 ....*....|..
gi 495111615 299 RMIRENFIYNFH 310
Cdd:PRK08699 291 DMLKQLAPYGFH 302
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
6-248 2.20e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 99.73  E-value: 2.20e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   6 VIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYIccenrgeqdacgicptcvkfnkLIHPDlhfvfpvi 85
Cdd:PRK09112  25 LFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLAFHLANHI----------------------LSHPD-------- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  86 kKKAGKDTVCD-DFI-ADWRNfVLQNPYFNLNHWLKEMGAENQQAQ--IFVKESDEIVRKLSLKSSQGGYKIMIIWLPEK 161
Cdd:PRK09112  75 -PAEAPETLADpDPAsPVWRQ-IAQGAHPNLLHITRPFDEKTGKFKtaITVDEIRRVGHFLSQTSGDGNWRIVIIDPADD 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 162 MNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQPEDADDIA---HRSEG 238
Cdd:PRK09112 153 MNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHLGSSQGSDGEITEallQRSKG 232
                        250
                 ....*....|
gi 495111615 239 NFLKALETIH 248
Cdd:PRK09112 233 SVRKALLLLN 242
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
3-219 2.80e-23

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 101.07  E-value: 2.80e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCEnrGEQDA-CGICPTCVKFNKLIHPDlhfv 81
Cdd:PRK14963  13 FDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNCS--GEDPKpCGECESCLAVRRGAHPD---- 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  82 fpVIKKKAGKDTVCDDfiadwrnfvlqnpyfnlnhwlkemgaenqqaqifVKESDEivrKLSLKSSQGGYKIMIIWLPEK 161
Cdd:PRK14963  87 --VLEIDAASNNSVED----------------------------------VRDLRE---KVLLAPLRGGRKVYILDEAHM 127
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495111615 162 MNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ 219
Cdd:PRK14963 128 MSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRTQHFRFRRLTEEEIAGKLR 185
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
3-238 3.12e-23

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 100.67  E-value: 3.12e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVf 82
Cdd:PRK14953  15 FKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCVEIDKGSFPDLIEI- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikkkagkDTVCDDFIADWRNfvlqnpyfnlnhwlkemgaenqqaqifVKESdeivrkLSLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK14953  94 ---------DAASNRGIDDIRA---------------------------LRDA------VSYTPIKGKYKVYIIDEAHML 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVL-----QTKYGLQPEDADDIAHRSE 237
Cdd:PRK14953 132 TKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTILSRCQRFIFSKPTKEQIKEYLkricnEEKIEYEEKALDLLAQASE 211

                 .
gi 495111615 238 G 238
Cdd:PRK14953 212 G 212
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
3-239 5.24e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 99.22  E-value: 5.24e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGR---------IPHAQLICGPEGTGKLPLAIAYARYICCENRGEQdACGICPTCVKFNKL 73
Cdd:PRK07940   4 WDDLVGQEAVVAELRAAARAARadvaaagsgMTHAWLFTGPPGSGRSVAARAFAAALQCTDPDEP-GCGECRACRTVLAG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  74 IHPDLHFVFPvikkkagkdtvcddfiadwrnfvlqnpyfnlnhwlkemgaenQQAQIFVKESDEIVRKLSLKSSQGGYKI 153
Cdd:PRK07940  83 THPDVRVVAP------------------------------------------EGLSIGVDEVRELVTIAARRPSTGRWRI 120
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 154 MIIWLPEKMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQPEDADDIA 233
Cdd:PRK07940 121 VVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRCRHVALRTPSVEAVAEVLVRRDGVDPETARRAA 200

                 ....*.
gi 495111615 234 HRSEGN 239
Cdd:PRK07940 201 RASQGH 206
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
9-361 2.64e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 96.15  E-value: 2.64e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   9 QEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVFP---VI 85
Cdd:PRK08058  11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVAPdgqSI 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  86 KkkagKDTVcddfiadwrnfvlqnpyfnlnHWLKEmgaEnqqaqiFVK---ESDEivrklslkssqggyKIMIIWLPEKM 162
Cdd:PRK08058  91 K----KDQI---------------------RYLKE---E------FSKsgvESNK--------------KVYIIEHADKM 122
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQtKYGLQPEDADDIAHRSeGNFLK 242
Cdd:PRK08058 123 TASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPLPPESLIQRLQ-EEGISESLATLLAGLT-NSVEE 200
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 243 ALEtihLSEENKLF--FELFINLMRLSYQRKIREMKQWSDAVASMGRERQKnflaycQRMIRENFIYNFhqRDLVYMN-- 318
Cdd:PRK08058 201 ALA---LSEDDWFAqaRALVIKLYEALHEKDLQSFVFVQEKWMPLFKEKDQ------QQLGLDLLLLIY--RDLLYLQlg 269
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 495111615 319 -------PEEQNFSTRFAPFVNERNVMGIMDELSEAQLHIGQNVNPKMVF 361
Cdd:PRK08058 270 eedrlvfREQKEMLQQLALSYSQQQIVAALELILEAKRRLNSNVNFQLVM 319
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
3-244 3.04e-21

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 95.26  E-value: 3.04e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCE-NRGEQDACGICPTCVKFNKLIHPDlhfv 81
Cdd:PRK14950  15 FAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTtNDPKGRPCGTCEMCRAIAEGSAVD---- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  82 fpVIKKKAGKDTVCDDfiadwrnfvlqnpyfnlnhwlkemgaenqqaqifvkeSDEIVRKLSLKSSQGGYKIMIIWLPEK 161
Cdd:PRK14950  91 --VIEMDAASHTSVDD-------------------------------------AREIIERVQFRPALARYKVYIIDEVHM 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 162 MNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ---TKYG--LQPEDADDIAHRS 236
Cdd:PRK14950 132 LSTAAFNALLKTLEEPPPHAIFILATTEVHKVPATILSRCQRFDFHRHSVADMAAHLRkiaAAEGinLEPGALEAIARAA 211

                 ....*...
gi 495111615 237 EGNFLKAL 244
Cdd:PRK14950 212 TGSMRDAE 219
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
14-251 1.38e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 91.02  E-value: 1.38e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  14 QRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRgEQDACGICPTCVKFNKLIHPDLHFVFPvikKKAGKDT 93
Cdd:PRK06090  13 QNWKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNY-QSEACGFCHSCELMQSGNHPDLHVIKP---EKEGKSI 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  94 VCDdfiadwrnfvlqnpyfnlnhwlkEMGAENQQAQifvkesdeivrklslKSSQ-GGYKIMIIWLPEKMNVECSNKLLK 172
Cdd:PRK06090  89 TVE-----------------------QIRQCNRLAQ---------------ESSQlNGYRLFVIEPADAMNESASNALLK 130
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495111615 173 LLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQPEDADDIAHRSEgnfLKALETIHLSE 251
Cdd:PRK06090 131 TLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAMQWLKGQGITVPAYALKLNMGSP---LKTLAMMKEGG 206
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
2-247 3.93e-20

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 91.37  E-value: 3.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   2 LFKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDlhfv 81
Cdd:PRK14962  12 TFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEGTFMD---- 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  82 fpVIKKKAgkdtvcddfiadwrnfvlqnpyfnlnhwlkemgAENQQaqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEK 161
Cdd:PRK14962  88 --VIELDA---------------------------------ASNRG----IDEIRKIRDAVGYRPMEGKYKVYIIDEVHM 128
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 162 MNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQT-----KYGLQPEDADDIAHRS 236
Cdd:PRK14962 129 LTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTIISRCQVIEFRNISDELIIKRLQEvaeaeGIEIDREALSFIAKRA 208
                        250
                 ....*....|.
gi 495111615 237 EGNFLKALETI 247
Cdd:PRK14962 209 SGGLRDALTML 219
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
3-244 1.68e-19

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 89.83  E-value: 1.68e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRG-EQDACGICPTCVKFNKLIHPDLHFV 81
Cdd:PRK14971  16 FESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNLTaDGEACNECESCVAFNEQRSYNIHEL 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  82 fpvikkkagkDTVCDDFIADWRNFVLQNPYfnlnhwlkemgaenqQAQIfvkesdeivrklslkssqGGYKIMIIWLPEK 161
Cdd:PRK14971  96 ----------DAASNNSVDDIRNLIEQVRI---------------PPQI------------------GKYKIYIIDEVHM 132
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 162 MNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ---TKYGL--QPEDADDIAHRS 236
Cdd:PRK14971 133 LSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTILSRCQIFDFNRIQVADIVNHLQyvaSKEGItaEPEALNVIAQKA 212

                 ....*...
gi 495111615 237 EGNFLKAL 244
Cdd:PRK14971 213 DGGMRDAL 220
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
14-207 8.19e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 86.33  E-value: 8.19e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  14 QRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVFPVIKKKAGKDT 93
Cdd:PRK06871  12 QQITQAFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPIDNKDIGVDQ 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  94 VcddfiadwrnfvlqnpyfnlnhwlKEMgaeNQQAQIFVKesdeivrklslkssQGGYKIMIIWLPEKMNVECSNKLLKL 173
Cdd:PRK06871  92 V------------------------REI---NEKVSQHAQ--------------QGGNKVVYIQGAERLTEAAANALLKT 130
                        170       180       190
                 ....*....|....*....|....*....|....
gi 495111615 174 LEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIH 207
Cdd:PRK06871 131 LEEPRPNTYFLLQADLSAALLPTIYSRCQTWLIH 164
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
3-238 3.97e-18

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 85.69  E-value: 3.97e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDlhfvf 82
Cdd:PRK05563  15 FEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICKAITNGSLMD----- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pVIkkkagkdtvcddfiadwrnfvlqnpyfnlnhwlkEM-GAENQQaqifVKESDEIVRKLSLKSSQGGYKIMIIwlPEk 161
Cdd:PRK05563  90 -VI----------------------------------EIdAASNNG----VDEIRDIRDKVKYAPSEAKYKVYII--DE- 127
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 162 mnV-----ECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLqtKYGLQPE--DADD--- 231
Cdd:PRK05563 128 --VhmlstGAFNALLKTLEEPPAHVIFILATTEPHKIPATILSRCQRFDFKRISVEDIVERL--KYILDKEgiEYEDeal 203

                 ....*....
gi 495111615 232 --IAHRSEG 238
Cdd:PRK05563 204 rlIARAAEG 212
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
14-200 8.06e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 83.58  E-value: 8.06e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  14 QRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVFPvikkKAGKDT 93
Cdd:PRK07993  12 EQLVGSYQAGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLTP----EKGKSS 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  94 VCDDFIADwrnfvlqnpyfnlnhwlkemgaenqqaqifvkesdeIVRKLSLKSSQGGYKImiIWLP--EKMNVECSNKLL 171
Cdd:PRK07993  88 LGVDAVRE------------------------------------VTEKLYEHARLGGAKV--VWLPdaALLTDAAANALL 129
                        170       180
                 ....*....|....*....|....*....
gi 495111615 172 KLLEEPPAMTVFLLVSEEPDAILQTIQSR 200
Cdd:PRK07993 130 KTLEEPPENTWFFLACREPARLLATLRSR 158
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
1-252 8.11e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 83.03  E-value: 8.11e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   1 MLFKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCEnrgeqdacGICPTCVKfNKLI---HPD 77
Cdd:PRK07399   1 NLFANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGLLSQ--------GSPSKNIR-RRLEegnHPD 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  78 LHFVFPvikkkagkdtvcddfiadwrNFVLQNPYFNLNHWLKEMGAENQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIW 157
Cdd:PRK07399  72 LLWVEP--------------------TYQHQGKLITASEAEEAGLKRKAPPQIRLEQIREIKRFLSRPPLEAPRKVVVIE 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 158 LPEKMNVECSNKLLKLLEEP-PAmtVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQtKYG----LQPEDAD-- 230
Cdd:PRK07399 132 DAETMNEAAANALLKTLEEPgNG--TLILIAPSPESLLPTIVSRCQIIPFYRLSDEQLEQVLK-RLGdeeiLNINFPEll 208
                        250       260
                 ....*....|....*....|...
gi 495111615 231 DIAHRSEGNFLKALETIH-LSEE 252
Cdd:PRK07399 209 ALAQGSPGAAIANIEQLQsIPPE 231
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
3-274 1.64e-17

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 84.10  E-value: 1.64e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENrgEQDACGICPTCVK-FNKLIhpdlhfv 81
Cdd:PRK07133  17 FDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSH--KTDLLEPCQECIEnVNNSL------- 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  82 fpvikkkagkdtvcdDFIadwrnfvlqnpyfnlnhwlkEMGAENQQAqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEK 161
Cdd:PRK07133  88 ---------------DII--------------------EMDAASNNG---VDEIRELIENVKNLPTQSKYKIYIIDEVHM 129
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 162 MNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEIskVLQTKYGLQPEDAD-------DIAH 234
Cdd:PRK07133 130 LSKSAFNALLKTLEEPPKHVIFILATTEVHKIPLTILSRVQRFNFRRISEDEI--VSRLEFILEKENISyeknalkLIAK 207
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 495111615 235 RSEGNFLKALE-----------TIHLSEENKLF----FELFINLMRLSYQRKIRE 274
Cdd:PRK07133 208 LSSGSLRDALSiaeqvsifgnnKITLKNVEELFglvsNENLINLLNLLYSKDIKE 262
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
1-368 4.56e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 80.85  E-value: 4.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   1 MLFKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYIccenrgeqdacgicptcvkfnklihpdlhf 80
Cdd:PRK05564   1 MSFHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIALKI------------------------------ 50
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  81 vfpvIKKKAGKDTVcdDFIadwrNFVLQNpyfnlnhwlkemgaenqQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPE 160
Cdd:PRK05564  51 ----LGKSQQREYV--DII----EFKPIN-----------------KKSIGVDDIRNIIEEVNKKPYEGDKKVIIIYNSE 103
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 161 KMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKY-GLQPEDADDIAHRSE-- 237
Cdd:PRK05564 104 KMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEEIEKFISYKYnDIKEEEKKSAIAFSDgi 183
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 238 -GNFLKALETIHLSEENKLFFELFINLmrlsYQRKIREMKQWSDAVASMgRERQKNFLAYCQRMIRENFIYNFHQRDLVY 316
Cdd:PRK05564 184 pGKVEKFIEDDSLKNIRNMSLEILKDI----KKSNINILLKYENFLIKY-KENWEEILTCILSYIRDSLLYKETGNEELI 258
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 495111615 317 MN----PEEQNFSTRFApfVNERNVMgiMDELSEAQLHIGQNVNPKMVFFDFSLKM 368
Cdd:PRK05564 259 INidkiEDIKHISEKFS--YKKLNKM--IEIINDTRDNLSSNVNPTLVFDSMLIKM 310
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
3-247 1.33e-16

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 81.33  E-value: 1.33e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDlhfvf 82
Cdd:PRK14965  15 FSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCVEITEGRSVD----- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pVIKKKAGKDTVCDDfiadwrnfvlqnpyfnlnhwlkemgaenqqaqifVKESDEIVRKLSLKSSqggYKIMIIWLPEKM 162
Cdd:PRK14965  90 -VFEIDGASNTGVDD----------------------------------IRELRENVKYLPSRSR---YKIFIIDEVHML 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVL-----QTKYGLQPEDADDIAHRSE 237
Cdd:PRK14965 132 STNAFNALLKTLEEPPPHVKFIFATTEPHKVPITILSRCQRFDFRRIPLQKIVDRLryiadQEGISISDAALALVARKGD 211
                        250
                 ....*....|
gi 495111615 238 GNFLKALETI 247
Cdd:PRK14965 212 GSMRDSLSTL 221
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
3-239 7.53e-16

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 78.95  E-value: 7.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLhfvf 82
Cdd:PRK14959  15 FAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCRKVTQGMHVDV---- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikkkagkdtvcddfiadwrnfvlqnpyfnlnhwLKEMGAENQQaqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK14959  91 -----------------------------------VEIDGASNRG----IDDAKRLKEAIGYAPMEGRYKVFIIDEAHML 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQPEDADD-----IAHRSE 237
Cdd:PRK14959 132 TREAFNALLKTLEEPPARVTFVLATTEPHKFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPaavrlIARRAA 211

                 ..
gi 495111615 238 GN 239
Cdd:PRK14959 212 GS 213
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
3-218 2.10e-15

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 77.83  E-value: 2.10e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLhfvf 82
Cdd:PRK08691  15 FADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQIDAGRYVDL---- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvIKKKAGKDTVCDDfiadwrnfvlqnpyfnlnhwLKEMgAENQQaqifvkesdeivrklsLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK08691  91 --LEIDAASNTGIDN--------------------IREV-LENAQ----------------YAPTAGKYKVYIIDEVHML 131
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVL 218
Cdd:PRK08691 132 SKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTVLSRCLQFVLRNMTAQQVADHL 187
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
3-204 5.35e-15

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 76.14  E-value: 5.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDlhfvf 82
Cdd:PRK14956  17 FRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEITKGISSD----- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pVIKKKAGKDTVCDDfIADWRNFVLQNPyfnlnhwlkeMGaenqqaqifvkesdeivrklslkssqGGYKIMIIWLPEKM 162
Cdd:PRK14956  92 -VLEIDAASNRGIEN-IRELRDNVKFAP----------MG--------------------------GKYKVYIIDEVHML 133
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRF 204
Cdd:PRK14956 134 TDQSFNALLKTLEEPPAHIVFILATTEFHKIPETILSRCQDF 175
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
9-204 6.05e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 75.00  E-value: 6.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   9 QEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICceNRGEQDACGicptcVKFNKLI----HPDLHFVfpv 84
Cdd:PRK08769   9 QQRAYDQTVAALDAGRLGHGLLICGPEGLGKRAVALALAEHVL--ASGPDPAAA-----QRTRQLIaagtHPDLQLV--- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  85 ikkkagkdtvcdDFIADwrnfvlqnpyfnlnhwlkeMGAENQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNV 164
Cdd:PRK08769  79 ------------SFIPN-------------------RTGDKLRTEIVIEQVREISQKLALTPQYGIAQVVIVDPADAINR 127
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 495111615 165 ECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRF 204
Cdd:PRK08769 128 AACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRL 167
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
3-238 1.81e-14

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 74.69  E-value: 1.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDlhfvf 82
Cdd:PRK08451  13 FDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSALENRHID----- 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pVIKKKAGKDTVCDDFiadwRNFVLQNPYfnlnhwlkemgaenqqaqifvkesdeivrklslKSSQGGYKIMIIWLPEKM 162
Cdd:PRK08451  88 -IIEMDAASNRGIDDI----RELIEQTKY---------------------------------KPSMARFKIFIIDEVHML 129
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQT-------KYglQPEDADDIAHR 235
Cdd:PRK08451 130 TKEAFNALLKTLEEPPSYVKFILATTDPLKLPATILSRTQHFRFKQIPQNSIISHLKTilekegvSY--EPEALEILARS 207

                 ...
gi 495111615 236 SEG 238
Cdd:PRK08451 208 GNG 210
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
3-204 2.17e-14

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 74.53  E-value: 2.17e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKfnklIHPDLHFVF 82
Cdd:PRK14952  12 FAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVA----LAPNGPGSI 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 PVIKKKAGKDTVCDDfiadwrnfvlqnpyfnlnhwlkemgaenqqaqifvkeSDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK14952  88 DVVELDAASHGGVDD-------------------------------------TRELRDRAFYAPAQSRYRIFIVDEAHMV 130
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRF 204
Cdd:PRK14952 131 TTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHY 172
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
3-238 3.36e-14

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 73.65  E-value: 3.36e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGE-QDACGICPTCvkfnklihpdlhfv 81
Cdd:PRK06305  16 FSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNPTEdQEPCNQCASC-------------- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  82 fpvikKKAGKDTVCDDFIADwrnfvlqnpyfnlnhwlkemGAENQQaqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEK 161
Cdd:PRK06305  82 -----KEISSGTSLDVLEID--------------------GASHRG----IEDIRQINETVLFTPSKSRYKIYIIDEVHM 132
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 162 MNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQPEDADD-----IAHRS 236
Cdd:PRK06305 133 LTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSReallpIARAA 212

                 ..
gi 495111615 237 EG 238
Cdd:PRK06305 213 QG 214
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
3-244 4.73e-14

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 73.54  E-value: 4.73e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKlihpdlhfvf 82
Cdd:PRK14960  14 FNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAVNE---------- 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikkkaGKdtvcddFIAdwrnfvlqnpyfnlnhwLKEMGAENQQAqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK14960  84 -------GR------FID-----------------LIEIDAASRTK---VEDTRELLDNVPYAPTQGRFKVYLIDEVHML 130
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQPEDAD-----DIAHRSE 237
Cdd:PRK14960 131 STHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADqdaiwQIAESAQ 210

                 ....*..
gi 495111615 238 GNFLKAL 244
Cdd:PRK14960 211 GSLRDAL 217
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
3-205 1.26e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 72.11  E-value: 1.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCvkfnklihpdlhfvf 82
Cdd:PRK06647  15 FNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSC--------------- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikKKAGKDTVCDDFIADwrnfvlqnpyfnlnhwlkemGAENQQAQIFVKESDEIVrklsLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK06647  80 ----KSIDNDNSLDVIEID--------------------GASNTSVQDVRQIKEEIM----FPPASSRYRVYIIDEVHML 131
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFN 205
Cdd:PRK06647 132 SNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKSRCQHFN 174
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
3-244 1.68e-13

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 71.65  E-value: 1.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKlihpdlhfvf 82
Cdd:PRK14957  15 FAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVAINN---------- 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikkkagkdtvcDDFIAdwrnfvlqnpyfnlnhwLKEMGAENQQAqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK14957  85 -------------NSFID-----------------LIEIDAASRTG---VEETKEILDNIQYMPSQGRYKVYLIDEVHML 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEIS---KVLQTKYGLQPEDA--DDIAHRSE 237
Cdd:PRK14957 132 SKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSRCIQLHLKHISQADIKdqlKIILAKENINSDEQslEYIAYHAK 211

                 ....*..
gi 495111615 238 GNFLKAL 244
Cdd:PRK14957 212 GSLRDAL 218
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
3-239 9.49e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 69.12  E-value: 9.49e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQD----ACGICPTCVKFNKLIHPDl 78
Cdd:PRK06645  20 FAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALITENttikTCEQCTNCISFNNHNHPD- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  79 hfvfpVIKKKAGKDTVCDDFiadwrnfvlqnpyfnlnhwlkemgaenqqaqifvkesDEIVRKLSLKSSQGGYKIMIIWL 158
Cdd:PRK06645  99 -----IIEIDAASKTSVDDI-------------------------------------RRIIESAEYKPLQGKHKIFIIDE 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 159 PEKMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQPEDADD-----IA 233
Cdd:PRK06645 137 VHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIealriIA 216

                 ....*.
gi 495111615 234 HRSEGN 239
Cdd:PRK06645 217 YKSEGS 222
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
3-316 1.01e-12

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 69.49  E-value: 1.01e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVf 82
Cdd:PRK05896  15 FKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCESINTNQSVDIVEL- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikkkagkDTVCDDFIADWRNFVlqNPYFNLNHWLKemgaenqqaqifvkesdeivrklslkssqggYKIMIIWLPEKM 162
Cdd:PRK05896  94 ---------DAASNNGVDEIRNII--DNINYLPTTFK-------------------------------YKVYIIDEAHML 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ---TKYGLQPEDA--DDIAHRSE 237
Cdd:PRK05896 132 STSAWNALLKTLEEPPKHVVFIFATTEFQKIPLTIISRCQRYNFKKLNNSELQELLKsiaKKEKIKIEDNaiDKIADLAD 211
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 238 GNFLKALE-----------TIHLSEENKLF----FELFINLMRLSYQRKIREMKQWSDAVASMGrerqKNFLAYCQRMIr 302
Cdd:PRK05896 212 GSLRDGLSildqlstfknsEIDIEDINKTFglvdNNKKINLIELIQKNDIEELRNLINELESKG----INFEAFCRDLI- 286
                        330
                 ....*....|....
gi 495111615 303 eNFIYNFhqrdLVY 316
Cdd:PRK05896 287 -NLLIDL----LVY 295
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
3-219 1.42e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 65.54  E-value: 1.42e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFnklihpdlhfvf 82
Cdd:PRK14969  15 FSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACLEI------------ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikkkagkdtvcddfiaDWRNFVLqnpyfnlnhwLKEM-GAENQQaqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEK 161
Cdd:PRK14969  83 ------------------DSGRFVD----------LIEVdAASNTQ----VDAMRELLDNAQYAPTRGRFKVYIIDEVHM 130
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495111615 162 MNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ 219
Cdd:PRK14969 131 LSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNLKQMPPPLIVSHLQ 188
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
3-253 1.76e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 64.83  E-value: 1.76e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKlihpdlhfvf 82
Cdd:PRK14961  15 FRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICKEIEK---------- 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikkkagkdTVCDDFIadwrnfvlqnpyfnlnhwlkEMGAENQQAqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK14961  85 ----------GLCLDLI--------------------EIDAASRTK---VEEMREILDNIYYSPSKSRFKVYLIDEVHML 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLqtKYGLQPEDAD-------DIAHR 235
Cdd:PRK14961 132 SRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTILSRCLQFKLKIISEEKIFNFL--KYILIKESIDtdeyalkLIAYH 209
                        250       260
                 ....*....|....*....|..
gi 495111615 236 SEGNFLKAL----ETIHLSEEN 253
Cdd:PRK14961 210 AHGSMRDALnlleHAINLGKGN 231
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
3-275 2.45e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 64.51  E-value: 2.45e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEqdacgicptcvkfnklihPDLHFVF 82
Cdd:PRK14970  16 FDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDD------------------PNEDFSF 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 PVIKKKAGKDTVCDDFiadwRNFVLQnpyfnlnhwlkemgaenqqaqifvkesdeiVRklsLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK14970  78 NIFELDAASNNSVDDI----RNLIDQ------------------------------VR---IPPQTGKYKIYIIDEVHML 120
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ---TKYGLQPED--ADDIAHRSE 237
Cdd:PRK14970 121 SSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFKRITIKDIKEHLAgiaVKEGIKFEDdaLHIIAQKAD 200
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 495111615 238 GNFLKALE-------------TIHLSEE--NKLFFELFINLMRLSYQRKIREM 275
Cdd:PRK14970 201 GALRDALSifdrvvtfcgkniTRQAVTEnlNILDYDTYINVTDLILENKIPEL 253
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
21-205 2.82e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 63.50  E-value: 2.82e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  21 KEGRIPHAQLICGpeGTGKLPLAIAYARYICCENRGEQDACGICPTCvkfnKLIH----PDLHFVFP---VIKKKAGKDT 93
Cdd:PRK07276  19 EQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSC----RLIEqgefSDVTVIEPqgqVIKTDTIREL 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  94 VcddfiadwRNFvlqnpyfnlnhwlKEMGAENQQaQIFvkesdeivrklslkssqggykimIIWLPEKMNVECSNKLLKL 173
Cdd:PRK07276  93 V--------KNF-------------SQSGYEGKQ-QVF-----------------------IIKDADKMHVNAANSLLKV 127
                        170       180       190
                 ....*....|....*....|....*....|...
gi 495111615 174 LEEP-PAMTVFLLVSEEpDAILQTIQSRTQRFN 205
Cdd:PRK07276 128 IEEPqSEIYIFLLTNDE-NKVLPTIKSRTQIFH 159
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
3-244 3.34e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 64.42  E-value: 3.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDlhfvf 82
Cdd:PRK14964  12 FKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNSNHPD----- 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pVIKKKAGKDTVCDDfiadwrnfvlqnpyfnlnhwlkemgaenqqaqifVKESDEIVRKLSLKSSqggYKIMIIWLPEKM 162
Cdd:PRK14964  87 -VIEIDAASNTSVDD----------------------------------IKVILENSCYLPISSK---FKVYIIDEVHML 128
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVL-----QTKYGLQPEDADDIAHRSE 237
Cdd:PRK14964 129 SNSAFNALLKTLEEPAPHVKFILATTEVKKIPVTIISRCQRFDLQKIPTDKLVEHLvdiakKENIEHDEESLKLIAENSS 208

                 ....*..
gi 495111615 238 GNFLKAL 244
Cdd:PRK14964 209 GSMRNAL 215
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
3-219 1.09e-10

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 62.60  E-value: 1.09e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQ--------DACGICPTCVKFNkli 74
Cdd:PRK14955  15 FADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDadylqevtEPCGECESCRDFD--- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  75 hpdlhfvfpvikkkAGKDTVCDDFIADWRNFVLQnpyfnlnhwlkemgaenqqaqifVKESDEIVRklsLKSSQGGYKIM 154
Cdd:PRK14955  92 --------------AGTSLNISEFDAASNNSVDD-----------------------IRLLRENVR---YGPQKGRYRVY 131
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495111615 155 IIWLPEKMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ 219
Cdd:PRK14955 132 IIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQ 196
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
3-204 2.09e-10

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 62.29  E-value: 2.09e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENrGEQ---DACGICPTC---VKFNKLihp 76
Cdd:PRK14948  15 FDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNCLN-SDKptpEPCGKCELCraiAAGNAL--- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  77 DlhfvfpVIKKKAGKDTvcddfiadwrnfvlqnpyfnlnhwlkemGAENqqaqifvkesdeiVRKLSLKSS----QGGYK 152
Cdd:PRK14948  91 D------VIEIDAASNT----------------------------GVDN-------------IRELIERAQfapvQARWK 123
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495111615 153 IMIIwlpekmnVEC-------SNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRF 204
Cdd:PRK14948 124 VYVI-------DEChmlstaaFNALLKTLEEPPPRVVFVLATTDPQRVLPTIISRCQRF 175
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
3-219 4.43e-10

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 61.11  E-value: 4.43e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCEN--------RGEQDACGICPTCVKFNkli 74
Cdd:PRK14954  15 FADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRmiddpvylQEVTEPCGECESCRDFD--- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  75 hpdlhfvfpvikkkAGKDTVCDDFIADWRNFVLQnpyfnlnhwlkemgaenqqaqifVKESDEIVRklsLKSSQGGYKIM 154
Cdd:PRK14954  92 --------------AGTSLNISEFDAASNNSVDD-----------------------IRQLRENVR---YGPQKGRYRVY 131
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495111615 155 IIWLPEKMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ 219
Cdd:PRK14954 132 IIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQ 196
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
26-254 1.50e-09

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 57.92  E-value: 1.50e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  26 PHAQLICGPEGTGKLPLAIAYARYICCENrgeqdACGICPTCVKFNKLIHpdlhfvfpvikkkagkdtvcddfiadwrnf 105
Cdd:PRK05818   7 THPLLLIERKGSFLKPFLYEYLTSIVCTK-----ANGFCKTCESCLKILN------------------------------ 51
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 106 vlqNPYFNLNHwlkemgaENQQAQIFVKESD-EIVRKLSLKS-SQGGYKIMIIWLPEKMNVECSNKLLKLLEEPPAMTVF 183
Cdd:PRK05818  52 ---GKYNDFYL-------IFDQKNPIKKEDAlSIINKLNRPSvESNGKKIYIIYGIEKLNKQSANSLLKLIEEPPKNTYG 121
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495111615 184 LLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGLQP------EDADDIAHRSEGNFLKALETIHLSEENK 254
Cdd:PRK05818 122 IFTTRNENNILNTILSRCVQYVVLSKEKKVPFKVESNDRYFQYillsfySVDEQLQAYNNGSFSKLKNIIETLINKK 198
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
137-218 3.29e-09

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 57.42  E-value: 3.29e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 137 EIVRKLSLKS-SQGGYKIMIIWLPEKMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNihgIKEPEIS 215
Cdd:PRK07132  76 SAINKLYFSSfVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFN---VKEPDQQ 152

                 ...
gi 495111615 216 KVL 218
Cdd:PRK07132 153 KIL 155
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
3-244 7.32e-09

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 57.58  E-value: 7.32e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQ-----DACGICPTCVKFNklihpd 77
Cdd:PRK12323  15 FTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGADGEggitaQPCGQCRACTEID------ 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  78 lhfvfpvikkkAGKDTvcdDFIadwrnfvlqnpyfnlnhwlkEMGAENQQAqifVKESDEIVRKLSLKSSQGGYKIMIIW 157
Cdd:PRK12323  89 -----------AGRFV---DYI--------------------EMDAASNRG---VDEMAQLLDKAVYAPTAGRFKVYMID 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 158 LPEKMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQTKYGlqpedADDIAHrsE 237
Cdd:PRK12323 132 EVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILG-----EEGIAH--E 204

                 ....*..
gi 495111615 238 GNFLKAL 244
Cdd:PRK12323 205 VNALRLL 211
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
11-216 3.51e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 54.42  E-value: 3.51e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  11 EAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDacgicptcVKFNKLIHPDLHFVFPvikkkAG 90
Cdd:PRK05917   4 AAWEALIQRVRDQKVPSAIILHGQDLSNLSARAYELASLILKETSPEAA--------YKISQKIHPDIHEFSP-----QG 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  91 KDtvcddfiadwRNFVLQNPyfnlnhwlkemgaenqqaqifvkesDEIVRKLSLKSSQGGYKIMIIWLPEKMNVECSNKL 170
Cdd:PRK05917  71 KG----------RLHSIETP-------------------------RAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAF 115
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 495111615 171 LKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISK 216
Cdd:PRK05917 116 LKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLSIHIPMEEKTLVSK 161
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
3-201 6.52e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.61  E-value: 6.52e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVkfnklihpDLhfvf 82
Cdd:PRK07764  14 FAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCV--------AL---- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikkkagkdtvcddfiadwrnfvlqnpyfnlnhwlkemgAENQQAQIFVKESDeivrklslKSSQGG------------ 150
Cdd:PRK07764  82 ----------------------------------------APGGPGSLDVTEID--------AASHGGvddarelreraf 113
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 151 -------YKIMIIwlPEKMNV--ECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRT 201
Cdd:PRK07764 114 fapaesrYKIFII--DEAHMVtpQGFNALLKIVEEPPEHLKFIFATTEPDKVIGTIRSRT 171
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
3-230 7.86e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 53.97  E-value: 7.86e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNKLIHPDLHFVF 82
Cdd:PRK14958  15 FQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDEGRFPDLFEVD 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 PVIKKKagkdtvcddfiadwrnfvlqnpyfnlnhwlkemgaenqqaqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK14958  95 AASRTK-------------------------------------------VEDTRELLDNIPYAPTKGRFKVYLIDEVHML 131
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFniHGIKEPEISKVLQTKYGLQPEDAD 230
Cdd:PRK14958 132 SGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLSRCLQF--HLAQLPPLQIAAHCQHLLKEENVE 197
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
3-206 4.60e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 51.77  E-value: 4.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCVKFNklihpDLHFVf 82
Cdd:PRK07003  15 FASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREID-----EGRFV- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  83 pvikkkagkdtvcdDFIadwrnfvlqnpyfnlnhwlkEMGAENQQAqifVKESDEIVRKLSLKSSQGGYKIMIIWLPEKM 162
Cdd:PRK07003  89 --------------DYV--------------------EMDAASNRG---VDEMAALLERAVYAPVDARFKVYMIDEVHML 131
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 495111615 163 NVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNI 206
Cdd:PRK07003 132 TNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNL 175
rfc PRK00440
replication factor C small subunit; Reviewed
3-48 7.11e-07

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 50.26  E-value: 7.11e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAqLICGPEGTGKLPLAIAYAR 48
Cdd:PRK00440  16 LDEIVGQEEIVERLKSYVKEKNMPHL-LFAGPPGTGKTTAALALAR 60
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
24-219 9.99e-07

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 50.88  E-value: 9.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  24 RIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTCV-----KFNKLIHPDlhfvfpvikkkAGKDTVCDDf 98
Cdd:PRK14949  36 RLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCVeiaqgRFVDLIEVD-----------AASRTKVDD- 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  99 iadwrnfvlqnpyfnlnhwlkemgaenqqaqifvkeSDEIVRKLSLKSSQGGYKIMIIwlPE-KMNVECS-NKLLKLLEE 176
Cdd:PRK14949 104 ------------------------------------TRELLDNVQYRPSRGRFKVYLI--DEvHMLSRSSfNALLKTLEE 145
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 495111615 177 PPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQ 219
Cdd:PRK14949 146 PPEHVKFLLATTDPQKLPVTVLSRCLQFNLKSLTQDEIGTQLN 188
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
119-206 1.30e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 49.07  E-value: 1.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 119 KEMGAENQQAQIFVKESDEIVRKLSLKSSQGGYKIMIIWLPEKMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQ 198
Cdd:PRK06581  58 RETSATSNAKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIR 137

                 ....*...
gi 495111615 199 SRTQRFNI 206
Cdd:PRK06581 138 SRCFKINV 145
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
2-253 2.52e-06

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 48.83  E-value: 2.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   2 LFKDVIGQEEAKQRLIAEVKEGRIPHAqLICGPEGTGKLPLAIAYARYICCENRGEQDAcgICPTCVKFN---KLIHPDL 78
Cdd:PRK12402  13 LLEDILGQDEVVERLSRAVDSPNLPHL-LVQGPPGSGKTAAVRALARELYGDPWENNFT--EFNVADFFDqgkKYLVEDP 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  79 HFVFPVIKKKAGKDTVCDDFiadwrnfvlqnpyfnlNHWLKEMGaenqqaqifvkesdeivrklSLKSSQGGYKIMIIWL 158
Cdd:PRK12402  90 RFAHFLGTDKRIRSSKIDNF----------------KHVLKEYA--------------------SYRPLSADYKTILLDN 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 159 PEKMNVECSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFNIHGIKEPEISKVLQT---KYGLQ--PEDADDIA 233
Cdd:PRK12402 134 AEALREDAQQALRRIMEQYSRTCRFIIATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESiaeAEGVDydDDGLELIA 213
                        250       260
                 ....*....|....*....|
gi 495111615 234 HRSEGNFLKALETIHLSEEN 253
Cdd:PRK12402 214 YYAGGDLRKAILTLQTAALA 233
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
3-47 6.30e-06

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 46.07  E-value: 6.30e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495111615   3 FKDVIGQEEAKQRLiAEVKE------------GRIPHAQLICGPEGTGKLPLAIAYA 47
Cdd:cd19501    3 FKDVAGCEEAKEEL-KEVVEflknpekftklgAKIPKGVLLVGPPGTGKTLLAKAVA 58
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
118-205 8.91e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 46.18  E-value: 8.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615 118 LKEMGAE--NQQAQIFVKE------SDEIVRKLSLKSSQggYKIMIIwLPEKMNVECSNKLLKLLEEPPAMTVFLLVSEE 189
Cdd:PRK08485  17 KEELINEfgKKNLRFFIKEefkiedAKEVIAEAYIAESE--EKIIVI-AAPSYGIEAQNALLKILEEPPKNICFIIVAKS 93
                         90
                 ....*....|....*.
gi 495111615 190 PDAILQTIQSRTQRFN 205
Cdd:PRK08485  94 KNLLLPTIRSRLIIEK 109
HflB COG0465
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
3-47 3.77e-05

ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440233 [Multi-domain]  Cd Length: 583  Bit Score: 45.41  E-value: 3.77e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495111615   3 FKDVIGQEEAKQRLiAEVKE------------GRIPHAQLICGPEGTGKLPLAIAYA 47
Cdd:COG0465  141 FDDVAGVDEAKEEL-QEIVDflkdpekftrlgAKIPKGVLLVGPPGTGKTLLAKAVA 196
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
3-205 1.34e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 43.74  E-value: 1.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQ-----DACGICPTCVKFNKLIHPD 77
Cdd:PRK09111  23 FDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGPDGDggptiDLCGVGEHCQAIMEGRHVD 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495111615  78 lhfvfpVIKKKAGKDTVCDDfiadwrnfvlqnpyfnlnhwlkemgaenqqaqifVKESDEIVRklsLKSSQGGYKIMII- 156
Cdd:PRK09111 103 ------VLEMDAASHTGVDD----------------------------------IREIIESVR---YRPVSARYKVYIId 139
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 495111615 157 ---WLPEKmnveCSNKLLKLLEEPPAMTVFLLVSEEPDAILQTIQSRTQRFN 205
Cdd:PRK09111 140 evhMLSTA----AFNALLKTLEEPPPHVKFIFATTEIRKVPVTVLSRCQRFD 187
PRK04195 PRK04195
replication factor C large subunit; Provisional
3-50 1.37e-04

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 43.76  E-value: 1.37e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 495111615   3 FKDVIGQEEAKQRL---IAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYI 50
Cdd:PRK04195  13 LSDVVGNEKAKEQLrewIESWLKGKPKKALLLYGPPGVGKTSLAHALANDY 63
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
3-67 1.43e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 40.62  E-value: 1.43e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495111615   3 FKDVIGQEEAKQRLIAEVKEGRIPHAQLICGPEGTGKLPLAIAYARYICCENRGEQDACGICPTC 67
Cdd:PRK07994  15 FAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNC 79
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
7-48 1.46e-03

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 40.34  E-value: 1.46e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 495111615   7 IGQEEAKQR--LIAE-VKEGRIP-HAQLICGPEGTGKLPLAIAYAR 48
Cdd:COG1224   41 VGQVEAREAagIVVKmIKEGKMAgKGILIVGPPGTGKTALAVAIAR 86
TIP49 pfam06068
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ...
6-48 2.72e-03

TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.


Pssm-ID: 399217 [Multi-domain]  Cd Length: 347  Bit Score: 39.21  E-value: 2.72e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 495111615    6 VIGQEEAKQR--LIAE-VKEGRIP-HAQLICGPEGTGKLPLAIAYAR 48
Cdd:pfam06068  26 LVGQEKAREAagVIVEmIKEGKIAgRAVLIAGPPGTGKTALAIAISK 72
ftsH CHL00176
cell division protein; Validated
2-47 5.17e-03

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 38.88  E-value: 5.17e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495111615   2 LFKDVIGQEEAKQRLiAEV----KEGR--------IPHAQLICGPEGTGKLPLAIAYA 47
Cdd:CHL00176 181 TFRDIAGIEEAKEEF-EEVvsflKKPErftavgakIPKGVLLVGPPGTGKTLLAKAIA 237
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
3-48 8.10e-03

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 37.56  E-value: 8.10e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495111615   3 FKDVIGQEEAKQ---RLIAEVKEGRIPHAQ--------LICGPEGTGKLPLAIAYAR 48
Cdd:COG1223    1 LDDVVGQEEAKKklkLIIKELRRRENLRKFglwpprkiLFYGPPGTGKTMLAEALAG 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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