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Conserved domains on  [gi|495124536|ref|WP_007849347|]
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MULTISPECIES: methyl-accepting chemotaxis protein [Cronobacter]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 1000955)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MCP_signal super family cl46910
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 53-512 3.25e-108

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


The actual alignment was detected with superfamily member PRK15048:

Pssm-ID: 481250 [Multi-domain]  Cd Length: 553  Bit Score: 333.13  E-value: 3.25e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  53 INHSRTVRVRLMEAMINQSLGKTSQaetsLEGANEFLQHAVETFDSYMASPRTPGEEEILAPYRQTWQNYLdNGLRPMIE 132
Cdd:PRK15048  65 INLSRSAVRMMMDSSNQQSNAKVEL----LDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYY-TALTELID 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 133 AATNNDVErfnqlASFTVPALDYQ--FENELLKLLSFREDYAHNLNLDAQEQFKYSLTLLGGFTIIFILILLAVFILIQR 210
Cdd:PRK15048 140 YLDYGNTG-----AYFAQPTQGMQnaMGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRR 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 211 RILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLTALEQMRQSLRNIIIQVRDSSDSVAHAADEIAAGNIDLSARTE 290
Cdd:PRK15048 215 MLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTE 294

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 291 EQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQTN 370
Cdd:PRK15048 295 QQASALEETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTN 374

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 371 ILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSAAAKEIKELIEQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLM 450
Cdd:PRK15048 375 ILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIM 454

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495124536 451 SELALSTGEQSRGIEQINLAVNQMDAVTQQNAALVEEASSAAMSLKEQSHLLKQTVDIFKVS 512
Cdd:PRK15048 455 GEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLA 516
 
Name Accession Description Interval E-value
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 53-512 3.25e-108

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 333.13  E-value: 3.25e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  53 INHSRTVRVRLMEAMINQSLGKTSQaetsLEGANEFLQHAVETFDSYMASPRTPGEEEILAPYRQTWQNYLdNGLRPMIE 132
Cdd:PRK15048  65 INLSRSAVRMMMDSSNQQSNAKVEL----LDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYY-TALTELID 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 133 AATNNDVErfnqlASFTVPALDYQ--FENELLKLLSFREDYAHNLNLDAQEQFKYSLTLLGGFTIIFILILLAVFILIQR 210
Cdd:PRK15048 140 YLDYGNTG-----AYFAQPTQGMQnaMGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRR 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 211 RILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLTALEQMRQSLRNIIIQVRDSSDSVAHAADEIAAGNIDLSARTE 290
Cdd:PRK15048 215 MLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTE 294

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 291 EQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQTN 370
Cdd:PRK15048 295 QQASALEETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTN 374

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 371 ILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSAAAKEIKELIEQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLM 450
Cdd:PRK15048 375 ILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIM 454

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495124536 451 SELALSTGEQSRGIEQINLAVNQMDAVTQQNAALVEEASSAAMSLKEQSHLLKQTVDIFKVS 512
Cdd:PRK15048 455 GEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLA 516
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
9-511 2.14e-95

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 299.24  E-value: 2.14e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   9 ITLGALIVIFLASSASNLWSLTRSNQALDDVNKEIRVVLSVVDPINHSRTVRVRLMEAMINQSLGKTSQAETSLEGANEF 88
Cdd:COG0840    3 ILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  89 LQHAVETFDSYMASPRTPGEEEILAPYRQTWQNYLDNGLRPMIEAATNNDVERFNQLASFTVPALDYQFENELLKLLSFR 168
Cdd:COG0840   83 ALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 169 EDYAHNLNLDAQEQFKYSLTLLGGFTIIFILILLAVFILIQRRILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLT 248
Cdd:COG0840  163 LAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLAD 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 249 ALEQMRQSLRNIIIQVRDSSDSVAHAADEIAAGNIDLSARTEEQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMR 328
Cdd:COG0840  243 AFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEAS 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 329 ESAQEGNQIMEEAV--------------ESMMELESSARRIDSITGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA 394
Cdd:COG0840  323 ELAEEGGEVVEEAVegieeiresveetaETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVA 402

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 395 SEVRNLAQRSSAAAKEIKELI--------------EQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLMSELALSTGEQ 460
Cdd:COG0840  403 DEVRKLAERSAEATKEIEELIeeiqseteeaveamEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQ 482

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|.
gi 495124536 461 SRGIEQINLAVNQMDAVTQQNAALVEEASSAAMSLKEQSHLLKQTVDIFKV 511
Cdd:COG0840  483 SAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 263-510 4.22e-69

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 222.16  E-value: 4.22e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   263 QVRDSSDSVAHAADEIAAGNIDLSARTEEQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMRESAQEGNQIMEEAV 342
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   343 ESMMELESSARRIDSITGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSAAAKEIKELI------- 415
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIkeiqeet 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   416 -------EQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLMSELALSTGEQSRGIEQINLAVNQMDAVTQQNAALVEEA 488
Cdd:smart00283 161 neavaamEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|..
gi 495124536   489 SSAAMSLKEQSHLLKQTVDIFK 510
Cdd:smart00283 241 SAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 290-487 3.47e-55

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 183.59  E-value: 3.47e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 290 EEQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQT 369
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 370 NILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSAAAKEIKELIEQSGTHITSGSEKVSRAGESMKAIINSVNQVSVL 449
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 495124536 450 MSELALSTGEQSRGIEQINLAVNQMDAVTQQNAALVEE 487
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEE 198
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 323-478 1.57e-49

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 168.00  E-value: 1.57e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  323 LAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQ 402
Cdd:pfam00015   3 LAQLASEEAQDGGKEVANVVGQMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  403 RSSAAAKEIKELI--------------EQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLMSELALSTGEQSRGIEQIN 468
Cdd:pfam00015  83 RSAQAAKEIEALIieiqkqtndstasiESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVN 162

                         170
                  ....*....|
gi 495124536  469 LAVNQMDAVT 478
Cdd:pfam00015 163 QAVARMDQVT 172
 
Name Accession Description Interval E-value
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 53-512 3.25e-108

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 333.13  E-value: 3.25e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  53 INHSRTVRVRLMEAMINQSLGKTSQaetsLEGANEFLQHAVETFDSYMASPRTPGEEEILAPYRQTWQNYLdNGLRPMIE 132
Cdd:PRK15048  65 INLSRSAVRMMMDSSNQQSNAKVEL----LDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYY-TALTELID 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 133 AATNNDVErfnqlASFTVPALDYQ--FENELLKLLSFREDYAHNLNLDAQEQFKYSLTLLGGFTIIFILILLAVFILIQR 210
Cdd:PRK15048 140 YLDYGNTG-----AYFAQPTQGMQnaMGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRR 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 211 RILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLTALEQMRQSLRNIIIQVRDSSDSVAHAADEIAAGNIDLSARTE 290
Cdd:PRK15048 215 MLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTE 294

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 291 EQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQTN 370
Cdd:PRK15048 295 QQASALEETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTN 374

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 371 ILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSAAAKEIKELIEQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLM 450
Cdd:PRK15048 375 ILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIM 454

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495124536 451 SELALSTGEQSRGIEQINLAVNQMDAVTQQNAALVEEASSAAMSLKEQSHLLKQTVDIFKVS 512
Cdd:PRK15048 455 GEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLA 516
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
67-511 2.62e-103

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 320.36  E-value: 2.62e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  67 MINQS-LGKTSQAETSLEGANEFLQHAVETFDSYMASPRTPGEEEILAPYRQTWQNYLDNGLRPMIEAATNNDVERFnql 145
Cdd:PRK15041  75 MMDQNnIGSGSTVAELMQSASISLKQAEKNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEF--- 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 146 asFTVPALDYQ--FENELLKLLSfREDYAHNLNL-DAQEQFKYSLTLLGGFTIIFILILLAVFILIQRRILKPLDIAHAQ 222
Cdd:PRK15041 152 --FDQPTQGYQdgFEKQYVAYME-QNDRLYDIAVsDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDS 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 223 CKKIAEGDLQNPIISHSGDEIGRMLTALEQMRQSLRNIIIQVRDSSDSVAHAADEIAAGNIDLSARTEEQAASLGETAAS 302
Cdd:PRK15041 229 IRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAAS 308

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 303 MEQLTSTVKHTSDNTHNADLLAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQTNILALNAAVEAAR 382
Cdd:PRK15041 309 MEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAAR 388

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 383 AGEQGRGFAVVASEVRNLAQRSSAAAKEIKELIEQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLMSELALSTGEQSR 462
Cdd:PRK15041 389 AGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSR 468

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
gi 495124536 463 GIEQINLAVNQMDAVTQQNAALVEEASSAAMSLKEQSHLLKQTVDIFKV 511
Cdd:PRK15041 469 GIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRI 517
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
9-511 2.14e-95

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 299.24  E-value: 2.14e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   9 ITLGALIVIFLASSASNLWSLTRSNQALDDVNKEIRVVLSVVDPINHSRTVRVRLMEAMINQSLGKTSQAETSLEGANEF 88
Cdd:COG0840    3 ILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  89 LQHAVETFDSYMASPRTPGEEEILAPYRQTWQNYLDNGLRPMIEAATNNDVERFNQLASFTVPALDYQFENELLKLLSFR 168
Cdd:COG0840   83 ALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 169 EDYAHNLNLDAQEQFKYSLTLLGGFTIIFILILLAVFILIQRRILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLT 248
Cdd:COG0840  163 LAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLAD 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 249 ALEQMRQSLRNIIIQVRDSSDSVAHAADEIAAGNIDLSARTEEQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMR 328
Cdd:COG0840  243 AFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEAS 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 329 ESAQEGNQIMEEAV--------------ESMMELESSARRIDSITGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA 394
Cdd:COG0840  323 ELAEEGGEVVEEAVegieeiresveetaETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVA 402

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 395 SEVRNLAQRSSAAAKEIKELI--------------EQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLMSELALSTGEQ 460
Cdd:COG0840  403 DEVRKLAERSAEATKEIEELIeeiqseteeaveamEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQ 482

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|.
gi 495124536 461 SRGIEQINLAVNQMDAVTQQNAALVEEASSAAMSLKEQSHLLKQTVDIFKV 511
Cdd:COG0840  483 SAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
85-511 3.62e-92

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 291.20  E-value: 3.62e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  85 ANEFLQHAVETFDSYMASprTPGEEEILAPYRQTWQNYldnglrpmieAATNNDVE------RFNQLASF-TVP------ 151
Cdd:PRK09793  90 ARASLTQSTTLFKSFMAM--TAGNEHVRALQKETEKSF----------ARWHNDLEhqatwlESNQLSDFlTAPvqgsqn 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 152 ALDYQFENELLKLLSFREDYAHnlnlDAQEQFKYSLTLLGGFTIIFILILLAVFILIQRRILKPLDIAHAQCKKIAEGDL 231
Cdd:PRK09793 158 AFDVNFEAWQLEINHVLEAASA----QSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPLAIIGSHFDSIAAGNL 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 232 QNPIISHSGDEIGRMLTALEQMRQSLRNIIIQVRDSSDSVAHAADEIAAGNIDLSARTEEQAASLGETAASMEQLTSTVK 311
Cdd:PRK09793 234 ARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVG 313

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 312 HTSDNTHNADLLAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQTNILALNAAVEAARAGEQGRGFA 391
Cdd:PRK09793 314 QNADNARQASELAKNAATTAQAGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFA 393

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 392 VVASEVRNLAQRSSAAAKEIKELIEQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLMSELALSTGEQSRGIEQINLAV 471
Cdd:PRK09793 394 VVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRGIEQVAQAV 473

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 495124536 472 NQMDAVTQQNAALVEEASSAAMSLKEQSHLLKQTVDIFKV 511
Cdd:PRK09793 474 SQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTL 513
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 263-510 4.22e-69

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 222.16  E-value: 4.22e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   263 QVRDSSDSVAHAADEIAAGNIDLSARTEEQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMRESAQEGNQIMEEAV 342
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   343 ESMMELESSARRIDSITGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSAAAKEIKELI------- 415
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIkeiqeet 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   416 -------EQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLMSELALSTGEQSRGIEQINLAVNQMDAVTQQNAALVEEA 488
Cdd:smart00283 161 neavaamEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|..
gi 495124536   489 SSAAMSLKEQSHLLKQTVDIFK 510
Cdd:smart00283 241 SAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 290-487 3.47e-55

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 183.59  E-value: 3.47e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 290 EEQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQT 369
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 370 NILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSAAAKEIKELIEQSGTHITSGSEKVSRAGESMKAIINSVNQVSVL 449
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 495124536 450 MSELALSTGEQSRGIEQINLAVNQMDAVTQQNAALVEE 487
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEE 198
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 323-478 1.57e-49

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 168.00  E-value: 1.57e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  323 LAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQ 402
Cdd:pfam00015   3 LAQLASEEAQDGGKEVANVVGQMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  403 RSSAAAKEIKELI--------------EQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLMSELALSTGEQSRGIEQIN 468
Cdd:pfam00015  83 RSAQAAKEIEALIieiqkqtndstasiESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVN 162

                         170
                  ....*....|
gi 495124536  469 LAVNQMDAVT 478
Cdd:pfam00015 163 QAVARMDQVT 172
TarH pfam02203
Tar ligand binding domain homolog; This entry represents the ligand-binding domain found in a ...
 26-172 9.25e-12

Tar ligand binding domain homolog; This entry represents the ligand-binding domain found in a number of methyl-accepting chemotaxis receptors, such as E.coli Tar (taxis to aspartate and repellents), which is a receptor for the attractant L-aspartate and also recognizes proteogenic amino acids, phthalic acid, Malic acid, 3,4-dihydroxymandelic acid, citrate, benzoate and derivatives, protocatechuate, vanillate, quinate, shikimate and dehydroshikimate (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 426656 [Multi-domain]  Cd Length: 152  Bit Score: 63.09  E-value: 9.25e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   26 LWSLTRSNQALDDV---NKEIRVVLSVVDpiNHSRTVRVRLMEAMINQSLGKTSQAETSLEGANEFLQHAVETFDSYMAS 102
Cdd:pfam02203   5 LSGLSRSNDALREVytnRLQQQAALADAW--LLLLQARLTLNRAGIAALLPDAPDAAELLARARESLAQSDAAWKAYLAL 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495124536  103 PRTPGEEEILA-PYRQTWQNYlDNGLRPMIEAATNNDVERFNQLASFTVPALDYQFENELLKLLSFREDYA 172
Cdd:pfam02203  83 PRTPDEEEALAaELKAKYDAL-QDGLAPLIAALRAGDLDAFFDQPTQKIQPLFEALYNAYLALRKFQNDAA 152
HAMP pfam00672
HAMP domain;
207-259 1.09e-07

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 48.39  E-value: 1.09e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 495124536  207 LIQRRILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLTALEQMRQSLRN 259
Cdd:pfam00672   1 LLARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
210-261 3.48e-07

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 46.86  E-value: 3.48e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 495124536   210 RRILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLTALEQMRQSLRNII 261
Cdd:smart00304   1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETI 52
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 182-258 8.62e-07

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 51.12  E-value: 8.62e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495124536 182 QFKYSLTLLGgFTIIFILILLAVFILIQRRILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLTALEQMRQSLR 258
Cdd:COG5000    4 QILFLLLLLL-IALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLK 79
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
3-498 4.09e-06

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 49.34  E-value: 4.09e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   3 VRLFSFITLGALIVIFLASSASNLWSLTRSNQALDDVNKEIRVVLSVVDPINHSRTVRVRLMEAMINQSLGKTSQAETSL 82
Cdd:COG2770   27 VLALISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536  83 EGANEFLQHAVETFDSYMASPRTPGEEEILAPYRQTWQNYLDNGLRPMIEAATNNDVERFNQLASFTVPALDYQFENELL 162
Cdd:COG2770  107 AALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAAL 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 163 KLLSFREDYAHNLNLDAQEQFKYSLTLLGGFTIIFILILLAVFILIQRRILKPLDIAHAQCKKIAEGDLQNPIISHSGDE 242
Cdd:COG2770  187 LAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDE 266

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 243 IGRMLTALEQMRQSLRNIIIQVRDSSDSVAHAADEIAAGNIDLSARTEEQAASLGETAASMEQLTSTVKHTSDNTHNADL 322
Cdd:COG2770  267 IGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLL 346

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 323 LAGSMRESAQEGNQIMEEAVESMMELESSARRIDSITGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQ 402
Cdd:COG2770  347 AADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAA 426

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 403 RSSAAAKEIKELIEQSGTHITSGSEKVSRAGESMKAIINSVNQVSVLMSELALSTGEQSRGIEQINLAVNQMDAVTQQNA 482
Cdd:COG2770  427 AAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELA 506

                        490
                 ....*....|....*.
gi 495124536 483 ALVEEASSAAMSLKEQ 498
Cdd:COG2770  507 EELLLLEGLLLLLLLE 522
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 213-257 4.90e-05

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 40.51  E-value: 4.90e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 495124536 213 LKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLTALEQMRQSL 257
Cdd:cd06225    1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
YesM COG2972
Sensor histidine kinase YesM [Signal transduction mechanisms];
181-265 1.46e-04

Sensor histidine kinase YesM [Signal transduction mechanisms];


Pssm-ID: 442211 [Multi-domain]  Cd Length: 445  Bit Score: 44.24  E-value: 1.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 181 EQFKYSLTLLGGFTIIFILILLAVFILIQRRILKPLDIAHAQCKKIAEGDLQnPIISHSGDEIGRMLTALEQMRQSLRNI 260
Cdd:COG2972  150 RGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV-RLEVSGNDEIGILARSFNEMVERIKEL 228


                 ....*
gi 495124536 261 IIQVR 265
Cdd:COG2972  229 IEEVY 233
4HB_MCP_1 pfam12729
Four helix bundle sensory module for signal transduction; This family is a four helix bundle ...
 1-183 4.32e-04

Four helix bundle sensory module for signal transduction; This family is a four helix bundle that operates as a ubiquitous sensory module in prokaryotic signal-transduction. The 4HB_MCP is always found between two predicted transmembrane helices indicating that it detects only extracellular signals. In many cases the domain is associated with a cytoplasmic HAMP domain suggesting that most proteins carrying the bundle might share the mechanism of transmembrane signalling which is well-characterized in E coli chemoreceptors. This domain recognizes citrate and TCA cycle intermediates, cis-aconitate, boric acid, Phenanthrene, pyrene and benzopyrene (Matilla et el., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 432749 [Multi-domain]  Cd Length: 181  Bit Score: 41.47  E-value: 4.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536    1 MTVR---LFSFITLGALIVIflaSSASNLWSLTRSNQALDDV-NKEIRVVLSVVDPINHSRTVRVRLMEAMINQSlgkTS 76
Cdd:pfam12729   2 LKIRtklILLFLLLALLLII---VGVVGLYSLKQINDNLDTMyEDRLLPIKWLGDIRANLLELRANLLELILTTD---PA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536   77 QAETSLEGANEFLQHAVETFDSYMASPRTPGEEEILAPYRQTWQNYlDNGLRPMIE-AATNNDVERFNQLASFTVPALDy 155
Cdd:pfam12729  76 ERDELLKDIEELRAEIDKLLEKYEKTILTDEEKKLFAEFKENLNAY-RAVRNKVLElAKAGNKDEAYQLYKTEGRPARE- 153

                         170       180
                  ....*....|....*....|....*...
gi 495124536  156 QFENELLKLLSFREDYAHNLNLDAQEQF 183
Cdd:pfam12729 154 AMIEALEELVDYNLKVAKEAYKDNKASY 181
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 195-434 2.03e-03

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 40.64  E-value: 2.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 195 IIFILILLAVFILIQRRILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLTALEQMRQSLRNIIIQVRDSSDSVAHA 274
Cdd:COG3850  125 LLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELYAELEEEEELEAEL 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 275 ADEIAAGNIDLSARTEEQAASLGETAASMEQLTSTVKHTSDNTHNADLLAGSMRESAQEGNQIMEEAVESMMELESSARR 354
Cdd:COG3850  205 ELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASALLLLELE 284

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 355 IDSITGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSAAAKEIKELIEQSGTHITSGSEKVSRAGE 434
Cdd:COG3850  285 LLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALEAAAAGAALAA 364
COG4192 COG4192
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ...
 172-255 2.06e-03

Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];


Pssm-ID: 443346 [Multi-domain]  Cd Length: 640  Bit Score: 40.83  E-value: 2.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495124536 172 AHNLNLDAQEQFKYSLTLLGGFTII-FILILLAVFILIQRRILKPLDIAHAQCKKIAEGDLQNPIISHSGDEIGRMLTAL 250
Cdd:COG4192  310 LVALNQETAQLVQQSGILLLAIALLsLLLAVLINYFYVRRRLVKRLNALSDAMAAIAAGDLDVPIPVDGNDEIGRIARLL 389


                 ....*
gi 495124536 251 EQMRQ 255
Cdd:COG4192  390 RVFRD 394
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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