|
Name |
Accession |
Description |
Interval |
E-value |
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
6-634 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 749.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 6 AADGQLANAIPGFKPREPQRQMAQAVSAAIEAATPLVVEAGTGTGKTYAYLAPALRA----GKKVIISTGSKALQDQLYS 81
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARALAEGRHLLIEAGTGTGKTLAYLVPALLAaretGKKVVISTATKALQEQLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 82 RDLPTVAKALEFKGRLALLKGRSNYLCLERLEQqALAGGDLPVQTLSDVIQLRGWANETVDGDISTCGrVAEDAPVWPLV 161
Cdd:COG1199 81 KDLPLLRKALGLPLRVALLKGRSNYLCLRRLEQ-ALQEGDDLDDEELLLARILAWASETWTGDRDELP-LPEDDELWRQV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 162 TSTNDNCLGTDCPLYKDCFVVKARKKAMEADVVVVNHHLFLADMVVKEsgfaELIPEAEVIIFDEAHQLPDIASQYFGQS 241
Cdd:COG1199 159 TSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALGE----ELLPEDDVLIIDEAHNLPDRARDMFSAE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 242 LSSRQLLDLARDIIIAYRTevKDTQQLQKCADRLAQSTQDFRLQLGD-PGFRGNLRELLADTS-ISRALLLLDDALELCY 319
Cdd:COG1199 235 LSSRSLLRLLRELRKLGLR--PGLKKLLDLLERLREALDDLFLALEEeEELRLALGELPDEPEeLLEALDALRDALEALA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 320 DVAKLSLGRSALLDAAFERATLYRARLKR-LKEINQPGYSYWYECNSRHFTLALTPLTVADKFQDVIAEKGGSWIFTSAT 398
Cdd:COG1199 313 EALEEELERLAELDALLERLEELLFALARfLRIAEDEGYVRWLEREGGDVRLHAAPLDPADLLRELLFSRARSVVLTSAT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 399 LSVNDDLHHFTERLGI-HEAKTLLLPSPFDYARQALLCVPRGLPQ-TNQPQAGKALARMLQPLIEANQGRCFMLCTSHAM 476
Cdd:COG1199 393 LSVGGPFDYFARRLGLdEDARTLSLPSPFDYENQALLYVPRDLPRpSDRDGYLEAIAEAIAELLEASGGNTLVLFTSYRA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 477 MRELAEQFRATMTLPVLLQGETSKSQLLEQFISAGNALLVATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKARMED 556
Cdd:COG1199 473 LEQVAELLRERLDIPVLVQGDGSREALLERFREGGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREA 552
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495143703 557 CRLRGGDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFLKSLPPTPRTRdIGEAARFLTDAA 634
Cdd:COG1199 553 LEARGGNGFMYAYLPPAVIKLKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTR-PEELRAFLERLD 629
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
10-618 |
6.80e-132 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 409.73 E-value: 6.80e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 10 QLANAIPGFKPREPQRQMAQAVSAAIEAATPLVVEAGTGTGKTYAYLAP----ALRAGKKVIISTGSKALQDQLYSRDLP 85
Cdd:PRK08074 248 KLSLAMPKYEKREGQQEMMKEVYTALRDSEHALIEAGTGTGKSLAYLLPaayfAKKKEEPVVISTYTIQLQQQLLEKDIP 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 86 TVAKALEFKGRLALLKGRSNYLCLERLEQqALAGGDlpvqTLSDVI----QLRGWANETVDGD-----ISTCGRVaedap 156
Cdd:PRK08074 328 LLQKIFPFPVEAALLKGRSHYLCLRKFEQ-ALQEED----DNYDVAltkaQLLVWLTETETGDldelnLPSGGKL----- 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 157 VWPLVTSTNDNCLGTDCPLYKDCFVVKARKKAMEADVVVVNHHLFLADMVVKESgfaeLIPEAEVIIFDEAHQLPDIASQ 236
Cdd:PRK08074 398 LWNRIASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLTSEEP----LLPSYEHIIIDEAHHFEEAASR 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 237 YFGQSLSSRQL---------LD----LARDIIIAYRTEVKDTQQLQKC----------ADRLAQSTQDF------RLQLG 287
Cdd:PRK08074 474 HLGEQFSYMSFqlllsrlgtLEedglLSKLAKLFKKSDQASRSSFRDLdeslkelkfeADELFQMLRSFvlkrkkQEQNG 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 288 DPGFRGNlRELLADTSISRALLLLDDALELCYDV-AKLSLGRSALLD-----AAFERATL--------YRARLKRLKEIN 353
Cdd:PRK08074 554 RLIYRYN-TESEKGKLWDAITELANRLCYDLRDLlTLLEAQKKELQEkmeseSAFLTGEYahlidlleKMAQLLQLLFEE 632
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 354 QPGYSYWYECNSRHFTLALT----PLTVADKFQD-VIAEKGgSWIFTSATLSVNDDLHHFTERLGIHE--AKTLLLPSPF 426
Cdd:PRK08074 633 DPDYVTWIEIDAKGAINATRlyaqPVEVAERLADeFFAKKK-SVILTSATLTVNGSFDYIIERLGLEDfyPRTLQIPSPF 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 427 DYARQALLCVPRGLP---QTNQPQAGKALARMLQPLIEANQGRCFMLCTSHAMMRELAEQFRATMTLP--VLL-QGETSK 500
Cdd:PRK08074 712 SYEEQAKLMIPTDMPpikDVPIEEYIEEVAAYIAKIAKATKGRMLVLFTSYEMLKKTYYNLKNEEELEgyVLLaQGVSSG 791
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 501 S--QLLEQFISAGNALLVATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPEAVITLK 578
Cdd:PRK08074 792 SraRLTKQFQQFDKAILLGTSSFWEGIDIPGDELSCLVIVRLPFAPPDQPVMEAKSEWAKEQGENPFQELSLPQAVLRFK 871
|
650 660 670 680
....*....|....*....|....*....|....*....|
gi 495143703 579 QGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFLKSLPPTP 618
Cdd:PRK08074 872 QGFGRLIRTETDRGTVFVLDRRLTTTSYGKYFLESLPTVP 911
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
17-618 |
1.44e-93 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 307.11 E-value: 1.44e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 17 GFKPREPQRQMAQAVSAAIEAATPLVVEAGTGTGKTYAYLAPAL---RAGKKVIISTGSKALQDQLYSRDLPTVAKALEF 93
Cdd:TIGR01407 243 GLEYRPEQLKLAELVLDQLTHSEKSLIEAPTGTGKTLGYLLPALyyaITEKPVVISTNTKVLQSQLLEKDIPLLNEILNF 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 94 KGRLALLKGRSNYLCLERLEQqALAGGDLPVQTLSDVIQLRGWANETVDGDISTCGRVAEDAPVWPLVTStnDNCLGTDC 173
Cdd:TIGR01407 323 KINAALIKGKSNYLSLGKFSQ-ILKDNTDNYEFNIFKMQVLVWLTETETGDLDELNLKGGNKMFFAQVRH--DGNLSKKD 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 174 PLYKDCFVVKARKKAMEADVVVVNHHLFLADMVVKEsgfaELIPEAEVIIFDEAHQLPDIASQYFGQSLSSRQLLDLARd 253
Cdd:TIGR01407 400 LFYEVDFYNRAQKNAEQAQILITNHAYLITRLVDNP----ELFPSFRDLIIDEAHHLPDIAENQLQEELDYADIKYQID- 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 254 iiiayRTEVKDTQQLQKcadRLAQSTQDFRLQLgdpgfrgnLRELLADTSISRALLLLDDALELCYDVAKLSLgrsALLD 333
Cdd:TIGR01407 475 -----LIGKGENEQLLK---RIQQLEKQEILEK--------LFDFETKDILKDLQAILDKLNKLLQIFSELSH---KTVD 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 334 AAFERATLYRARLKRLKEINQPGYSYWYEC----NSRHFTLALTPLTVADKFQDVIAEKGGSWIFTSATLSVNDDLHHFT 409
Cdd:TIGR01407 536 QLRKFDLALKDDFKNIEQSLKEGHTSWISIenlqQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHSFESFP 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 410 ERLGIHEAK-TLLLPSPFDYARQALLCVPRGLP---QTNQPQAGKALARMLQPLIEANQGRCFMLCTSHAMMRELAEQFR 485
Cdd:TIGR01407 616 QLLGLTDVHfNTIEPTPLNYAENQRVLIPTDAPaiqNKSLEEYAQEIASYIIEITAITSPKILVLFTSYEMLHMVYDMLN 695
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 486 ATMT---LPVLLQGET-SKSQLLEQFISAGNALLVATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKARMEDCRLRG 561
Cdd:TIGR01407 696 ELPEfegYEVLAQGINgSRAKIKKRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQKLEQEG 775
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 495143703 562 GDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFLKSLPPTP 618
Cdd:TIGR01407 776 KNPFYDYVLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLPEYL 832
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
459-617 |
3.14e-53 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 179.68 E-value: 3.14e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 459 LIEANQGRCFMLCTSHAMMRELAEQFRATMT---LPVLLQ-GETSKSQLLEQFISAG-NALLVATS--SFWEGVDVRGDA 531
Cdd:pfam13307 3 LLKVIPGGVLVFFPSYSYLEKVAERLKESGLekgIEIFVQpGEGSREKLLEEFKKKGkGAVLFGVCggSFSEGIDFPGDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 532 LSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFL 611
Cdd:pfam13307 83 LRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLP 162
|
....*.
gi 495143703 612 KSLPPT 617
Cdd:pfam13307 163 KWLPPG 168
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
474-603 |
1.62e-41 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 147.04 E-value: 1.62e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 474 HAMMRELAEQFRATMTL----PVLLQGETSKS--QLLEQF---ISAGNALLVATSS--FWEGVDVRGDALSLVIIDKLPF 542
Cdd:smart00491 1 YRYLEQVVEYWKENGILeinkPVFIEGKDSGEteELLEKYsaaCEARGALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495143703 543 TSPDDPLLKARMEDCRLRG-GDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVM 603
Cdd:smart00491 81 PNPDSPILRARLEYLDEKGgIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
503-600 |
3.32e-11 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 61.85 E-value: 3.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 503 LLEQFISAGNALL-VATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKARMEDCR-------LRGGDPFDEvqlpEAV 574
Cdd:cd18788 57 YMERVVSRGALLLaVCRGKVSEGIDFSDDLGRAVIMVGIPYPNTKDPILKLKMDDLEylrdkglLTGEDWYTF----QAM 132
|
90 100
....*....|....*....|....*.
gi 495143703 575 ITLKQGVGRLIRDVDDRGVLVICDNR 600
Cdd:cd18788 133 RAVNQAIGRAIRHKNDYGAIVLLDKR 158
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
6-634 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 749.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 6 AADGQLANAIPGFKPREPQRQMAQAVSAAIEAATPLVVEAGTGTGKTYAYLAPALRA----GKKVIISTGSKALQDQLYS 81
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARALAEGRHLLIEAGTGTGKTLAYLVPALLAaretGKKVVISTATKALQEQLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 82 RDLPTVAKALEFKGRLALLKGRSNYLCLERLEQqALAGGDLPVQTLSDVIQLRGWANETVDGDISTCGrVAEDAPVWPLV 161
Cdd:COG1199 81 KDLPLLRKALGLPLRVALLKGRSNYLCLRRLEQ-ALQEGDDLDDEELLLARILAWASETWTGDRDELP-LPEDDELWRQV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 162 TSTNDNCLGTDCPLYKDCFVVKARKKAMEADVVVVNHHLFLADMVVKEsgfaELIPEAEVIIFDEAHQLPDIASQYFGQS 241
Cdd:COG1199 159 TSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALGE----ELLPEDDVLIIDEAHNLPDRARDMFSAE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 242 LSSRQLLDLARDIIIAYRTevKDTQQLQKCADRLAQSTQDFRLQLGD-PGFRGNLRELLADTS-ISRALLLLDDALELCY 319
Cdd:COG1199 235 LSSRSLLRLLRELRKLGLR--PGLKKLLDLLERLREALDDLFLALEEeEELRLALGELPDEPEeLLEALDALRDALEALA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 320 DVAKLSLGRSALLDAAFERATLYRARLKR-LKEINQPGYSYWYECNSRHFTLALTPLTVADKFQDVIAEKGGSWIFTSAT 398
Cdd:COG1199 313 EALEEELERLAELDALLERLEELLFALARfLRIAEDEGYVRWLEREGGDVRLHAAPLDPADLLRELLFSRARSVVLTSAT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 399 LSVNDDLHHFTERLGI-HEAKTLLLPSPFDYARQALLCVPRGLPQ-TNQPQAGKALARMLQPLIEANQGRCFMLCTSHAM 476
Cdd:COG1199 393 LSVGGPFDYFARRLGLdEDARTLSLPSPFDYENQALLYVPRDLPRpSDRDGYLEAIAEAIAELLEASGGNTLVLFTSYRA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 477 MRELAEQFRATMTLPVLLQGETSKSQLLEQFISAGNALLVATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKARMED 556
Cdd:COG1199 473 LEQVAELLRERLDIPVLVQGDGSREALLERFREGGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREA 552
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495143703 557 CRLRGGDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFLKSLPPTPRTRdIGEAARFLTDAA 634
Cdd:COG1199 553 LEARGGNGFMYAYLPPAVIKLKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTR-PEELRAFLERLD 629
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
10-618 |
6.80e-132 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 409.73 E-value: 6.80e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 10 QLANAIPGFKPREPQRQMAQAVSAAIEAATPLVVEAGTGTGKTYAYLAP----ALRAGKKVIISTGSKALQDQLYSRDLP 85
Cdd:PRK08074 248 KLSLAMPKYEKREGQQEMMKEVYTALRDSEHALIEAGTGTGKSLAYLLPaayfAKKKEEPVVISTYTIQLQQQLLEKDIP 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 86 TVAKALEFKGRLALLKGRSNYLCLERLEQqALAGGDlpvqTLSDVI----QLRGWANETVDGD-----ISTCGRVaedap 156
Cdd:PRK08074 328 LLQKIFPFPVEAALLKGRSHYLCLRKFEQ-ALQEED----DNYDVAltkaQLLVWLTETETGDldelnLPSGGKL----- 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 157 VWPLVTSTNDNCLGTDCPLYKDCFVVKARKKAMEADVVVVNHHLFLADMVVKESgfaeLIPEAEVIIFDEAHQLPDIASQ 236
Cdd:PRK08074 398 LWNRIASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLTSEEP----LLPSYEHIIIDEAHHFEEAASR 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 237 YFGQSLSSRQL---------LD----LARDIIIAYRTEVKDTQQLQKC----------ADRLAQSTQDF------RLQLG 287
Cdd:PRK08074 474 HLGEQFSYMSFqlllsrlgtLEedglLSKLAKLFKKSDQASRSSFRDLdeslkelkfeADELFQMLRSFvlkrkkQEQNG 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 288 DPGFRGNlRELLADTSISRALLLLDDALELCYDV-AKLSLGRSALLD-----AAFERATL--------YRARLKRLKEIN 353
Cdd:PRK08074 554 RLIYRYN-TESEKGKLWDAITELANRLCYDLRDLlTLLEAQKKELQEkmeseSAFLTGEYahlidlleKMAQLLQLLFEE 632
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 354 QPGYSYWYECNSRHFTLALT----PLTVADKFQD-VIAEKGgSWIFTSATLSVNDDLHHFTERLGIHE--AKTLLLPSPF 426
Cdd:PRK08074 633 DPDYVTWIEIDAKGAINATRlyaqPVEVAERLADeFFAKKK-SVILTSATLTVNGSFDYIIERLGLEDfyPRTLQIPSPF 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 427 DYARQALLCVPRGLP---QTNQPQAGKALARMLQPLIEANQGRCFMLCTSHAMMRELAEQFRATMTLP--VLL-QGETSK 500
Cdd:PRK08074 712 SYEEQAKLMIPTDMPpikDVPIEEYIEEVAAYIAKIAKATKGRMLVLFTSYEMLKKTYYNLKNEEELEgyVLLaQGVSSG 791
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 501 S--QLLEQFISAGNALLVATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPEAVITLK 578
Cdd:PRK08074 792 SraRLTKQFQQFDKAILLGTSSFWEGIDIPGDELSCLVIVRLPFAPPDQPVMEAKSEWAKEQGENPFQELSLPQAVLRFK 871
|
650 660 670 680
....*....|....*....|....*....|....*....|
gi 495143703 579 QGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFLKSLPPTP 618
Cdd:PRK08074 872 QGFGRLIRTETDRGTVFVLDRRLTTTSYGKYFLESLPTVP 911
|
|
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
10-622 |
7.76e-115 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 358.76 E-value: 7.76e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 10 QLANAIPGFKPREPQRQMAQAVS---AAIEAATP--LVVEAGTGTGKTYAYLAP----ALRAGKKVIISTGSKALQDQLY 80
Cdd:PRK11747 16 ALQEQLPGFIPRAGQRQMIAEVAktlAGEYLKDGriLVIEAGTGVGKTLSYLLAgipiARAEKKKLVISTATVALQEQLV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 81 SRDLPTVAKALEFKGRLALLKGRSNYLCLERLE--------QQALAGGDLPVQTLSDVIQL------------RGWanet 140
Cdd:PRK11747 96 SKDLPLLLKISGLDFKFTLAKGRGRYVCPRKLAalasdegtQQDLLLFLDDELTPPDEEEQkllarlakalatGKW---- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 141 vDGDISTCGRVAEDApVWPLVTSTNDNCLGTDCPLYKDCFVVKARKKAMEADVVVVNHHLFLADMvvkESGFAELIPEAE 220
Cdd:PRK11747 172 -DGDRDHWPEPIDDS-LWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADL---ELGGGVVLPDPE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 221 --VIIFDEAHQLPDIASQYFGQSLS-------SRQLLDLARDIIIAYRT-EVKDTQQLQKCADRLAQSTQDFRLQL---- 286
Cdd:PRK11747 247 nlLYVLDEGHHLPDVARDHFAASAElkgtadwLEKLLKLLTKLVALIMEpPLALPERLNAHCEELRELLASLNQILnlfl 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 287 ----GDPGFR---GNLRELLadtsisrallllddaLELCYDVAKLS------LGR-SALLDAAFERATLYRARLKRLkeI 352
Cdd:PRK11747 327 paggEEARYRfemGELPEEL---------------LELAERLAKLTekllglLEKlLNDLSEAMKTGKIDIVRLERL--L 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 353 NQPG-YSYWYECNSRHFTLALTP-------------LTVADKFQDVIA-----EKGGS-----W------IFTSATLSVN 402
Cdd:PRK11747 390 LELGrALGRLEALSKLWRLAAKEdqesgapmarwitREERDGQGDYLFhaspiRVGDQlerllWsrapgaVLTSATLRSL 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 403 DDLHHFTERLGIHE---AKTLLLPSPFDYARQALLCVPRgLPQ--TNQPQAGKALARMLQPLIEANQGrCFMLCTSHAMM 477
Cdd:PRK11747 470 NSFDRFQEQSGLPEkdgDRFLALPSPFDYPNQGKLVIPK-MRAepDNEEAHTAEMAEFLPELLEKHKG-SLVLFASRRQM 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 478 RELAEQFRATMTLPVLLQGETSKSQLLE---QFISAGNA-LLVATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKAR 553
Cdd:PRK11747 548 QKVADLLPRDLRLMLLVQGDQPRQRLLEkhkKRVDEGEGsVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATL 627
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495143703 554 MEDCRLRGGDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFLKSLPPTPRTRD 622
Cdd:PRK11747 628 AEWLKSRGGNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIE 696
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
17-618 |
1.44e-93 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 307.11 E-value: 1.44e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 17 GFKPREPQRQMAQAVSAAIEAATPLVVEAGTGTGKTYAYLAPAL---RAGKKVIISTGSKALQDQLYSRDLPTVAKALEF 93
Cdd:TIGR01407 243 GLEYRPEQLKLAELVLDQLTHSEKSLIEAPTGTGKTLGYLLPALyyaITEKPVVISTNTKVLQSQLLEKDIPLLNEILNF 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 94 KGRLALLKGRSNYLCLERLEQqALAGGDLPVQTLSDVIQLRGWANETVDGDISTCGRVAEDAPVWPLVTStnDNCLGTDC 173
Cdd:TIGR01407 323 KINAALIKGKSNYLSLGKFSQ-ILKDNTDNYEFNIFKMQVLVWLTETETGDLDELNLKGGNKMFFAQVRH--DGNLSKKD 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 174 PLYKDCFVVKARKKAMEADVVVVNHHLFLADMVVKEsgfaELIPEAEVIIFDEAHQLPDIASQYFGQSLSSRQLLDLARd 253
Cdd:TIGR01407 400 LFYEVDFYNRAQKNAEQAQILITNHAYLITRLVDNP----ELFPSFRDLIIDEAHHLPDIAENQLQEELDYADIKYQID- 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 254 iiiayRTEVKDTQQLQKcadRLAQSTQDFRLQLgdpgfrgnLRELLADTSISRALLLLDDALELCYDVAKLSLgrsALLD 333
Cdd:TIGR01407 475 -----LIGKGENEQLLK---RIQQLEKQEILEK--------LFDFETKDILKDLQAILDKLNKLLQIFSELSH---KTVD 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 334 AAFERATLYRARLKRLKEINQPGYSYWYEC----NSRHFTLALTPLTVADKFQDVIAEKGGSWIFTSATLSVNDDLHHFT 409
Cdd:TIGR01407 536 QLRKFDLALKDDFKNIEQSLKEGHTSWISIenlqQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHSFESFP 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 410 ERLGIHEAK-TLLLPSPFDYARQALLCVPRGLP---QTNQPQAGKALARMLQPLIEANQGRCFMLCTSHAMMRELAEQFR 485
Cdd:TIGR01407 616 QLLGLTDVHfNTIEPTPLNYAENQRVLIPTDAPaiqNKSLEEYAQEIASYIIEITAITSPKILVLFTSYEMLHMVYDMLN 695
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 486 ATMT---LPVLLQGET-SKSQLLEQFISAGNALLVATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKARMEDCRLRG 561
Cdd:TIGR01407 696 ELPEfegYEVLAQGINgSRAKIKKRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQKLEQEG 775
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 495143703 562 GDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFLKSLPPTP 618
Cdd:TIGR01407 776 KNPFYDYVLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLPEYL 832
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
459-617 |
3.14e-53 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 179.68 E-value: 3.14e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 459 LIEANQGRCFMLCTSHAMMRELAEQFRATMT---LPVLLQ-GETSKSQLLEQFISAG-NALLVATS--SFWEGVDVRGDA 531
Cdd:pfam13307 3 LLKVIPGGVLVFFPSYSYLEKVAERLKESGLekgIEIFVQpGEGSREKLLEEFKKKGkGAVLFGVCggSFSEGIDFPGDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 532 LSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFL 611
Cdd:pfam13307 83 LRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLP 162
|
....*.
gi 495143703 612 KSLPPT 617
Cdd:pfam13307 163 KWLPPG 168
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
474-603 |
1.62e-41 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 147.04 E-value: 1.62e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 474 HAMMRELAEQFRATMTL----PVLLQGETSKS--QLLEQF---ISAGNALLVATSS--FWEGVDVRGDALSLVIIDKLPF 542
Cdd:smart00491 1 YRYLEQVVEYWKENGILeinkPVFIEGKDSGEteELLEKYsaaCEARGALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495143703 543 TSPDDPLLKARMEDCRLRG-GDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVM 603
Cdd:smart00491 81 PNPDSPILRARLEYLDEKGgIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| PRK07246 |
PRK07246 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
14-614 |
1.99e-35 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 180905 [Multi-domain] Cd Length: 820 Bit Score: 142.90 E-value: 1.99e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 14 AIPGFKPREPQRQMAQAVSAAIEAATPLVVEAGTGTGKTYAYLAPAL-RAGK-KVIISTGSKALQDQLYSRDlptvAKAL 91
Cdd:PRK07246 240 ALLGLEERPKQESFAKLVGEDFHDGPASFIEAQTGIGKTYGYLLPLLaQSDQrQIIVSVPTKILQDQIMAEE----VKAI 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 92 E--FKGRLALLKGRSNYLCLERLEQQalaggdLPVQTLSDVI-----QLRGWANETVDGDISTCGRVAEDAPVWPLVTst 164
Cdd:PRK07246 316 QevFHIDCHSLKGPQNYLKLDAFYDS------LQQNDDNRLVnrykmQLLVWLTETETGDLDEIKQKQRYAAYFDQLK-- 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 165 NDNCLGTDCPLYKDCFVVKARKKAMEADVVVVNHHLFLaDMVVKESGFAElipeAEVIIFDEAHQLPDIASQYFGQSLSS 244
Cdd:PRK07246 388 HDGNLSQSSLFYDYDFWKRSYEKAKTARLLITNHAYFL-TRVQDDKDFAR----NKVLVFDEAQKLMLQLEQLSRHQLNI 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 245 RQLLDLARDIIIAYRTevkdtqQLQKcadRLAQSTQdFRLQLGDPGFRGNLRELLADTSISRALLLLddalelcydvakl 324
Cdd:PRK07246 463 TSFLQTIQKALSGPLP------LLQK---RLLESIS-FELLQLSEQFYQGKERQLIHDSLSRLHQYF------------- 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 325 slgrSALLDAAFERatlyrarlkrLKEINQPGYS-YWYEC---NSRHFTLALTPLTVADKFQDVIAEKGGSwIFTSATLS 400
Cdd:PRK07246 520 ----SELEVAGFQE----------LQAFFATAEGdYWLESekqSEKRVTYLNSASKAFTHFSQLLPETCKT-YFVSATLQ 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 401 VNDDLHhFTERLGIHEAKTLLLPSpfDYARQALLCVPRGLPQTNQ---PQAGKALARMLQPLiEANQGRCFMLCTSHAMM 477
Cdd:PRK07246 585 ISPRVS-LADLLGFEEYLFHKIEK--DKKQDQLVVVDQDMPLVTEtsdEVYAEEIAKRLEEL-KQLQQPILVLFNSKKHL 660
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 478 ---RELAEQfratMTLPVLLQGET-SKSQLLEQFISAGNALLVATSSFWEGVD-VRGDALsLVIIDKLPFTSPDDPLLKA 552
Cdd:PRK07246 661 lavSDLLDQ----WQVSHLAQEKNgTAYNIKKRFDRGEQQILLGLGSFWEGVDfVQADRM-IEVITRLPFDNPEDPFVKK 735
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495143703 553 RMEDCRLRGGDPFDEVQLPEAVITLKQGVGRLIRDVDDRGVLVICDNRLVMRPYGAVFLKSL 614
Cdd:PRK07246 736 MNQYLLQEGKNPFYDYFLPMTILRLKQAIGRTMRREDQKSAVLILDRRILTKSYGKQILASL 797
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
503-600 |
3.32e-11 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 61.85 E-value: 3.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 503 LLEQFISAGNALL-VATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKARMEDCR-------LRGGDPFDEvqlpEAV 574
Cdd:cd18788 57 YMERVVSRGALLLaVCRGKVSEGIDFSDDLGRAVIMVGIPYPNTKDPILKLKMDDLEylrdkglLTGEDWYTF----QAM 132
|
90 100
....*....|....*....|....*.
gi 495143703 575 ITLKQGVGRLIRDVDDRGVLVICDNR 600
Cdd:cd18788 133 RAVNQAIGRAIRHKNDYGAIVLLDKR 158
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
16-82 |
4.51e-06 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 47.87 E-value: 4.51e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495143703 16 PGFKPREPQRQmaqAVSAAIEAATPLVVEAGTGTGKTYAYLAPALRAGK-----KVIISTGSKALQDQLYSR 82
Cdd:smart00487 5 GFEPLRPYQKE---AIEALLSGLRDVILAAPTGSGKTLAALLPALEALKrgkggRVLVLVPTRELAEQWAEE 73
|
|
| Csf4_U |
cd09708 |
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly ... |
24-589 |
5.65e-06 |
|
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DinG family DNA helicase
Pssm-ID: 187839 [Multi-domain] Cd Length: 632 Bit Score: 49.59 E-value: 5.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 24 QRQMAQAVSAAIEAATPLVVEAGTGTGKTYAYLAPAL-----RAGKKVIISTGSKALQDQLYS--RDLPTVAKA------ 90
Cdd:cd09708 2 QALFYRNCLTSLRQKRIGMLEASTGVGKTLAMIMAALtmlkeRPDQKIAIAVPTLALMGQLWSelERLTAEGLAgpvqag 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 91 -----LEFKGRLAL--LKGRSNYLC-LERLEQQA-LAGGDLPVQ-----------TLSDVIQLRGWANETVDGDISTCGR 150
Cdd:cd09708 82 ffpgsQEFVSPGALqeLLDQSDGPGdKDAVVRLWmGQGGPRKVAplfnrmrdvtlLIHDTADIRGYVSYREQWDSLPRCS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 151 VAEDAPVWplVTSTNDNCLGTDCPLYKDCFVVKARKKAmEADVVVVNHHLFLADMVVKESGFAE----LIPEAEVIIFDE 226
Cdd:cd09708 162 AMSRAPTK--MASMTHDLKALATLNPQDFVTEDEEDKR-WVTSLVESREYYARKSRILACTHTMlkwgLLPQPDILIVDE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 227 AHQLPDIASQYFGQSLSSRQLLdlaRDIIIAYR-------TEVKDTQQLQKCADRLAQSTQDFRLQLGDPG-----FRGN 294
Cdd:cd09708 239 AHLFEQNISRVYSNALSLRMLR---FHLEVSHRktgaigsAVVAAVSAVSHRLRQVSALGDGQTLCLDAGNkeletLFAD 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 295 LRELLADTSISRALLLLDDAlelcyDVAKLSLGRSALLDAAFERA--------------TLYRARLKRLKEINqpgySYW 360
Cdd:cd09708 316 LDAALEIKSTPNKKALSVVK-----DVKKARIILDNAITAIQGKQstvylqfspdrrfpSLIVGREDLGKVMG----GLW 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 361 YECNSRHFTLALTpLTVADKFqdviaeKGGSWIFTSATLSVNDDLHHFTERLGIHEAKTLLLPSPFDYARQALLCVP--R 438
Cdd:cd09708 387 KDVTHGAIIVSAT-LYLPDRF------GQMSCDYLKRVLSLPLSRLDTPSPIVAPWVRNLIPHLHVPNAKARFLLSRpvG 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 439 GLPQTNQPQAG--KALARMLQPLIEANQGRCFMLCTSHAMMRELAEQFRATMTLPVLLQGETSK-SQLLEQFISAGNA-- 513
Cdd:cd09708 460 KTEQGDANLAGwlENVSLSTAAILRKAQGGTLVLTTAFSHISAIGQLVELGIPAEIVIQSEKNRlASAEQQFLALYANgi 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 514 --LLVATSSFWEGVDV--------RGDALSLVIIDKLPFTspddpLLKARMEDCRLRGGDPFDEVqLPEAVITLKQGVGR 583
Cdd:cd09708 540 qpVLIAAGGAWTGIDLhdpsvspdKDNLLTDLIITCAPFG-----LNRSLSMLKRIRKTSVRPEI-INESLMMLRQGLGR 613
|
....*.
gi 495143703 584 LIRDVD 589
Cdd:cd09708 614 LVRHPD 619
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
32-135 |
8.50e-05 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 43.39 E-value: 8.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 32 SAAIEAATP---LVVEAGTGTGKTYAYLAPALRA------GKKVIISTGSKALQDQLYSRdlptVAKALEFKG-RLALLK 101
Cdd:pfam00270 5 AEAIPAILEgrdVLVQAPTGSGKTLAFLLPALEAldkldnGPQALVLAPTRELAEQIYEE----LKKLGKGLGlKVASLL 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 495143703 102 GRSNYlcleRLEQQALAGGDLPVQT---LSDVIQLRG 135
Cdd:pfam00270 81 GGDSR----KEQLEKLKGPDILVGTpgrLLDLLQERK 113
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
18-82 |
1.98e-04 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 44.25 E-value: 1.98e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495143703 18 FKPREPQRQMAQAVSAAIEAA-TPLVVEAGTGTGKTY--AYLAPALRAGKKVIISTGSKALQDQLYSR 82
Cdd:COG1061 79 FELRPYQQEALEALLAALERGgGRGLVVAPTGTGKTVlaLALAAELLRGKRVLVLVPRRELLEQWAEE 146
|
|
| DEXDc2 |
smart00488 |
DEAD-like helicases superfamily; |
18-247 |
5.92e-04 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214693 [Multi-domain] Cd Length: 289 Bit Score: 42.37 E-value: 5.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 18 FKPREPQRQMAQAVSAAIEAATPLVVEAGTGTGKTYAYLAPAL----------RAGKKVIISTGSKALQ---DQLYSRDL 84
Cdd:smart00488 7 YEPYPIQYEFMEELKRVLDRGKIGILESPTGTGKTLSLLCLTLtwlrsfperiQKIKLIYLSRTVSEIEkrlEELRKLMQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 85 PTVAKALEFKGRLA-----LLKGRSNYLCLERLEQQALAGGDLpVQTLS----DVIQL-----RGWA------NETVDGD 144
Cdd:smart00488 87 KVEYESDEESEKQAqllheLGREKPKVLGLSLTSRKNLCLNPE-VRTLKqnglVVDEVcrsltASKArkyryeNPKVERC 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 145 ----ISTCGRVAEDAP--VWPLVTSTNDNCLGTDCPLYkdcfvvkARKKAME-ADVVVVNHHLFLADmvvKESGFAELIP 217
Cdd:smart00488 166 pfyeNTEFLLVRDLLPaeVYDIEDLLELGKRLGGCPYF-------ASRKAIEfANVVVLPYQYLLDP---KIRQALSIEL 235
|
250 260 270
....*....|....*....|....*....|
gi 495143703 218 EAEVIIFDEAHQLPDIASQYFGQSLSSRQL 247
Cdd:smart00488 236 KDSIVIFDEAHNLDNVCISALSSELSRRSL 265
|
|
| rad3 |
TIGR00604 |
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are ... |
511-600 |
2.20e-03 |
|
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are DNA-DNA helicases that funciton in the initiation of transcription and nucleotide excision repair as part of the TFIIH complex. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273169 [Multi-domain] Cd Length: 705 Bit Score: 41.24 E-value: 2.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495143703 511 GNALL-VATSSFWEGVDVRGDALSLVIIDKLPFTSPDDPLLKARMEdcRLRGGDPFDEVQL---PEAVITLKQGVGRLIR 586
Cdd:TIGR00604 583 GAVLLsVAGGKVSEGIDFCDDLGRAVIMVGIPYEYTESRILLARLE--FLRDQYPIRENQDfyeFDAMRAVNQAIGRVIR 660
|
90
....*....|....
gi 495143703 587 DVDDRGVLVICDNR 600
Cdd:TIGR00604 661 HKDDYGSIVLLDKR 674
|
|
| DEXHc_Mtr4-like |
cd18024 |
DEXH-box helicase domain of ATP-dependent RNA helicase Mtr4; Mtr4 (also known as DOB1 or ... |
19-84 |
3.49e-03 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase Mtr4; Mtr4 (also known as DOB1 or SKIV2L2) is a type II DEAD box helicase that plays a role in the processing of structured RNAs, including the maturation of 5.8S ribosomal RNA (rRNA)and is part of the TRAMP complex that is involved in exosome-mediated degradation of aberrant RNAs. Mtr4 belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350782 [Multi-domain] Cd Length: 205 Bit Score: 39.35 E-value: 3.49e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495143703 19 KPREPQRQMA------QAVS-AAIEAATPLVVEAGTGTGKT----YAyLAPALRAGKKVIISTGSKALQDQLYsRDL 84
Cdd:cd18024 21 PPGNPARTYPftldpfQKTAiACIERNESVLVSAHTSAGKTvvaeYA-IAQSLRDKQRVIYTSPIKALSNQKY-REL 95
|
|
| DEXHc_RE |
cd17926 |
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family ... |
20-82 |
5.27e-03 |
|
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350684 [Multi-domain] Cd Length: 146 Bit Score: 37.67 E-value: 5.27e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 495143703 20 PREPQRQmaqAVSA--AIEAATPLVVEAGTGTGKTY-AYLAPALRAGKKVIISTGSKALQDQLYSR 82
Cdd:cd17926 1 LRPYQEE---ALEAwlAHKNNRRGILVLPTGSGKTLtALALIAYLKELRTLIVVPTDALLDQWKER 63
|
|
| |
