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Conserved domains on  [gi|495177836|ref|WP_007902628|]
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lipopolysaccharide assembly protein LapB [Leyella stercorea]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 66-330 1.89e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 1.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  66 ALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVYQKV-DP 144
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAgLL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 145 DGAVAMLEKLRTVKPDYP-VDAAAGRMYSRNGQLKSAMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVSLAQKGIQ 223
Cdd:COG2956   93 DRAEELLEKLLELDPDDAeALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALK 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 224 KYPYYG--SFNRVVLYAsdKQKNYPTAVEYGDKLFAATDTvkyTANDYTYYADALLNVGRIDDAIKAYKHIPEVAPENKE 301
Cdd:COG2956  173 LDPDCAraLLLLAELYL--EQGDYEEAIAALERALEQDPD---YLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247

                        250       260
                 ....*....|....*....|....*....
gi 495177836 302 VNKLiSDAYLKAKKFDESVAAYEAYLAAK 330
Cdd:COG2956  248 LLAL-ADLLERKEGLEAALALLERQLRRH 275
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 66-330 1.89e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 1.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  66 ALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVYQKV-DP 144
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAgLL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 145 DGAVAMLEKLRTVKPDYP-VDAAAGRMYSRNGQLKSAMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVSLAQKGIQ 223
Cdd:COG2956   93 DRAEELLEKLLELDPDDAeALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALK 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 224 KYPYYG--SFNRVVLYAsdKQKNYPTAVEYGDKLFAATDTvkyTANDYTYYADALLNVGRIDDAIKAYKHIPEVAPENKE 301
Cdd:COG2956  173 LDPDCAraLLLLAELYL--EQGDYEEAIAALERALEQDPD---YLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247

                        250       260
                 ....*....|....*....|....*....
gi 495177836 302 VNKLiSDAYLKAKKFDESVAAYEAYLAAK 330
Cdd:COG2956  248 LLAL-ADLLERKEGLEAALALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 50-329 1.79e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.47  E-value: 1.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   50 VKAFKKTYKKDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANP 129
Cdd:TIGR02917 454 AKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNL 533

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  130 TSYVRYATVY-QKVDPDGAVAMLEKLRTVKP-DYPVDAAAGRMYSRNGQLKSAMSHYDKVAD--PTTIEDYILFdyALTA 205
Cdd:TIGR02917 534 RAILALAGLYlRTGNEEEAVAWLEKAAELNPqEIEPALALAQYYLGKGQLKKALAILNEAADaaPDSPEAWLML--GRAQ 611

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  206 YALEEYDKAVSLAQKGIQKYPYYGSFNRVVLYASDKQKNYPTAVEYgdkLFAATDTVKYTANDYTYYADALLNVGRIDDA 285
Cdd:TIGR02917 612 LAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITS---LKRALELKPDNTEAQIGLAQLLLAAKRTESA 688

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 495177836  286 IKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAYEAYLAA 329
Cdd:TIGR02917 689 KKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKR 732
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 68-154 6.41e-05

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 45.84  E-value: 6.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   68 GRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVYQKVDPDGA 147
Cdd:PRK11447  358 GDAALKANNLAQAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPGNTNAVRGLANLYRQQSPEKA 437


                  ....*..
gi 495177836  148 VAMLEKL 154
Cdd:PRK11447  438 LAFIASL 444
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 66-330 1.89e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 1.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  66 ALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVYQKV-DP 144
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAgLL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 145 DGAVAMLEKLRTVKPDYP-VDAAAGRMYSRNGQLKSAMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVSLAQKGIQ 223
Cdd:COG2956   93 DRAEELLEKLLELDPDDAeALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALK 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 224 KYPYYG--SFNRVVLYAsdKQKNYPTAVEYGDKLFAATDTvkyTANDYTYYADALLNVGRIDDAIKAYKHIPEVAPENKE 301
Cdd:COG2956  173 LDPDCAraLLLLAELYL--EQGDYEEAIAALERALEQDPD---YLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247

                        250       260
                 ....*....|....*....|....*....
gi 495177836 302 VNKLiSDAYLKAKKFDESVAAYEAYLAAK 330
Cdd:COG2956  248 LLAL-ADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 95-349 8.80e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.30  E-value: 8.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  95 AEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVYQKV-DPDGAVAMLEKLRTVKPD-YPVDAAAGRMYS 172
Cdd:COG2956    8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRgEYDRAIRIHQKLLERDPDrAEALLELAQDYL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 173 RNGQLKSAMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVSLAQKGIQKYPYYGSFNRVVLYASDKQKNYPTAVEYG 252
Cdd:COG2956   88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEAL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 253 DKLFAATdtvKYTANDYTYYADALLNVGRIDDAIKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAYEAYLAAKGE 332
Cdd:COG2956  168 EKALKLD---PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244

                        250
                 ....*....|....*..
gi 495177836 333 EctyKEYDNFADIYLEQ 349
Cdd:COG2956  245 D---DLLLALADLLERK 258
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 50-290 2.02e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 2.02e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  50 VKAFKKTYKKDATAIAA---LGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEP 126
Cdd:COG2956   28 IDLLEEALELDPETVEAhlaLGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDP 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 127 ANPTSYVRYATVYQKV-DPDGAVAMLEKLRTVKPDYP-VDAAAGRMYSRNGQLKSAMSHYDKV--ADPTTIEDYILfdYA 202
Cdd:COG2956  108 DDAEALRLLAEIYEQEgDWEKAIEVLERLLKLGPENAhAYCELAELYLEQGDYDEAIEALEKAlkLDPDCARALLL--LA 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 203 LTAYALEEYDKAVSLAQKGIQKYPYYGSFNRVVLYASDKQKNYPTAVEYGDKLFAATDtvkyTANDYTYYADALLNVGRI 282
Cdd:COG2956  186 ELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP----SDDLLLALADLLERKEGL 261


                 ....*...
gi 495177836 283 DDAIKAYK 290
Cdd:COG2956  262 EAALALLE 269
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 55-225 3.08e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 3.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  55 KTYKKDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVR 134
Cdd:COG2956  104 ELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLL 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 135 YATVYQKV-DPDGAVAMLEKLRTVKPDY-PVDAAAGRMYSRNGQLKSAMSHYDKVADpTTIEDYILFDYALTAYALEEYD 212
Cdd:COG2956  184 LAELYLEQgDYEEAIAALERALEQDPDYlPALPRLAELYEKLGDPEEALELLRKALE-LDPSDDLLLALADLLERKEGLE 262

                        170
                 ....*....|...
gi 495177836 213 KAVSLAQKGIQKY 225
Cdd:COG2956  263 AALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 48-182 2.62e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.20  E-value: 2.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  48 DQVKAFKKTYKKDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPA 127
Cdd:COG2956  131 EVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPD 210

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 495177836 128 NPTSYVRYATVYQKV-DPDGAVAMLEKLRTVKPDYPVDAAAGRMYSRNGQLKSAMS 182
Cdd:COG2956  211 YLPALPRLAELYEKLgDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALA 266
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 60-186 6.12e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 6.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  60 DATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVY 139
Cdd:COG4783    3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 495177836 140 QKV-DPDGAVAMLEKLRTVKPDYP-VDAAAGRMYSRNGQLKSAMSHYDK 186
Cdd:COG4783   83 LKAgDYDEALALLEKALKLDPEHPeAYLRLARAYRALGRPDEAIAALEK 131
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
59-228 4.53e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.86  E-value: 4.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  59 KDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATV 138
Cdd:COG0457    6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 139 YQKV-DPDGAVAMLEKLRTVKPDYP-VDAAAGRMYSRNGQLKSAMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVS 216
Cdd:COG0457   86 LQALgRYEEALEDYDKALELDPDDAeALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165

                        170
                 ....*....|..
gi 495177836 217 LAQKGIQKYPYY 228
Cdd:COG0457  166 LLEKLEAAALAA 177
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 60-162 4.57e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.38  E-value: 4.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  60 DATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVY 139
Cdd:COG3914  111 NAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNAL 190

                         90       100
                 ....*....|....*....|....
gi 495177836 140 QKV-DPDGAVAMLEKLRTVKPDYP 162
Cdd:COG3914  191 QDLgRLEEAIAAYRRALELDPDNA 214
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 55-161 6.12e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.73  E-value: 6.12e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  55 KTYKKDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVR 134
Cdd:COG4783   32 ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLR 111

                         90       100
                 ....*....|....*....|....*...
gi 495177836 135 YATVYQKV-DPDGAVAMLEKLRTVKPDY 161
Cdd:COG4783  112 LARAYRALgRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 87-189 2.74e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 49.62  E-value: 2.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  87 AIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVY-QKVDPDGAVAMLEKLRTVKPDYPvDA 165
Cdd:COG4235    9 ALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALlAAGDTEEAEELLERALALDPDNP-EA 87

                         90       100
                 ....*....|....*....|....*.
gi 495177836 166 A--AGRMYSRNGQLKSAMSHYDKVAD 189
Cdd:COG4235   88 LylLGLAAFQQGDYAEAIAAWQKLLA 113
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
60-220 4.25e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 4.25e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  60 DATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVY 139
Cdd:COG0457   41 DAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLAL 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 140 QKV-DPDGAVAMLEKLRTVKPDYP-VDAAAGRMYSRNGQLKSAMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVSL 217
Cdd:COG0457  121 LELgRYDEAIEAYERALELDPDDAdALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALL 200


                 ...
gi 495177836 218 AQK 220
Cdd:COG0457  201 LAL 203
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 59-170 8.98e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.08  E-value: 8.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  59 KDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATV 138
Cdd:COG4235   15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                         90       100       110
                 ....*....|....*....|....*....|...
gi 495177836 139 Y-QKVDPDGAVAMLEKLRTVKPDYPVDAAAGRM 170
Cdd:COG4235   95 AfQQGDYAEAIAAWQKLLALLPADAPARLLEAS 127
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
168-385 1.09e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.62  E-value: 1.09e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 168 GRMYSRNGQLKSAMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVSLAQKGIQKYPYYGS--FNRVVLYAsdKQKNY 245
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEalNNLGLALQ--ALGRY 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 246 PTAVEYGDKlfaATDTVKYTANDYTYYADALLNVGRIDDAIKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAYEA 325
Cdd:COG0457   93 EEALEDYDK---ALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEK 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 326 YLAAKGEECTYKEYDNFADIYLEQSEAAADEAAKKAALQKAADIYGTIAEKYDYAAVYAL 385
Cdd:COG0457  170 LEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALAL 229
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 198-333 1.31e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 1.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 198 LFDYALTAYALEEYDKAVSLAQKGIQKYPYYGSFNRVVLYASDKQKNYPTAVEYGDKlfaATDTVKYTANDYTYYADALL 277
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHE---ALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 495177836 278 NVGRIDDAIKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAYEAYLAAKGEE 333
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 50-329 1.79e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.47  E-value: 1.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   50 VKAFKKTYKKDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANP 129
Cdd:TIGR02917 454 AKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNL 533

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  130 TSYVRYATVY-QKVDPDGAVAMLEKLRTVKP-DYPVDAAAGRMYSRNGQLKSAMSHYDKVAD--PTTIEDYILFdyALTA 205
Cdd:TIGR02917 534 RAILALAGLYlRTGNEEEAVAWLEKAAELNPqEIEPALALAQYYLGKGQLKKALAILNEAADaaPDSPEAWLML--GRAQ 611

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  206 YALEEYDKAVSLAQKGIQKYPYYGSFNRVVLYASDKQKNYPTAVEYgdkLFAATDTVKYTANDYTYYADALLNVGRIDDA 285
Cdd:TIGR02917 612 LAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITS---LKRALELKPDNTEAQIGLAQLLLAAKRTESA 688

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 495177836  286 IKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAYEAYLAA 329
Cdd:TIGR02917 689 KKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKR 732
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
88-329 2.58e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.85  E-value: 2.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  88 IKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVYQKV-DPDGAVAMLEKLRTVKPDYPVDAA 166
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLgRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 167 A-GRMYSRNGQLKSAMSHYDKV--ADPTTIEdyILFDYALTAYALEEYDKAVSLAQKGIQKYPYYGSFNRVVLYASDKQK 243
Cdd:COG0457   81 NlGLALQALGRYEEALEDYDKAleLDPDDAE--ALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 244 NYPTAVEYGDKLFAATDTVKYTANDYTYYADALLNVGRIDDAIKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAY 323
Cdd:COG0457  159 RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAAL 238


                 ....*.
gi 495177836 324 EAYLAA 329
Cdd:COG0457  239 ALYQYR 244
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 66-331 4.63e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.31  E-value: 4.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   66 ALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATV-YQKVDP 144
Cdd:TIGR02917 436 LLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIdIQEGNP 515

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  145 DGAVAMLEKLRTVKP-DYPVDAAAGRMYSRNGQLKSAMSHYDKVA--DPTTIEDYIlfdyALTAYALE--EYDKAVSLAQ 219
Cdd:TIGR02917 516 DDAIQRFEKVLTIDPkNLRAILALAGLYLRTGNEEEAVAWLEKAAelNPQEIEPAL----ALAQYYLGkgQLKKALAILN 591

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  220 kgiqkypyygsfnrvvlyasDKQKNYPTAVEYGDKLfaatdtvkytandytyyADALLNVGRIDDAIKAYKHIPEVAPEN 299
Cdd:TIGR02917 592 --------------------EAADAAPDSPEAWLML-----------------GRAQLAAGDLNKAVSSFKKLLALQPDS 634

                         250       260       270
                  ....*....|....*....|....*....|..
gi 495177836  300 KEVNKLISDAYLKAKKFDESVAAYEAYLAAKG 331
Cdd:TIGR02917 635 ALALLLLADAYAVMKNYAKAITSLKRALELKP 666
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
124-349 6.33e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 47.31  E-value: 6.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 124 YEPANPTSYVRYATVYQKV-DPDGAVAMLEKLRTVKPDYP-VDAAAGRMYSRNGQLKSAMSHYDKVADPTTIEDYILFDY 201
Cdd:COG0457    3 LDPDDAEAYNNLGLAYRRLgRYEEAIEDYEKALELDPDDAeALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 202 ALTAYALEEYDKAVSLAQKGIQKYPYYGSFNRVVLYASDKQKNYPTAVEYGDKlfaATDTVKYTANDYTYYADALLNVGR 281
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYER---ALELDPDDADALYNLGIALEKLGR 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495177836 282 IDDAIKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAYEAYLAAKGEECTYKEYDNFADIYLEQ 349
Cdd:COG0457  160 YEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLAL 227
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 180-328 7.07e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 7.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836 180 AMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVSLAQKGIQKYPYYGS--FNRVVLYAsdKQKNYPTAVEYGDKLFA 257
Cdd:COG3914   63 AAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEalFNLGNLLL--ALGRLEEALAALRRALA 140

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495177836 258 ATDTvkyTANDYTYYADALLNVGRIDDAIKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAYEAYLA 328
Cdd:COG3914  141 LNPD---FAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 46-299 3.39e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 3.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   46 TKDQVKAFKKTYKKDATAIA---ALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGT 122
Cdd:TIGR02917 549 EEEAVAWLEKAAELNPQEIEpalALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLL 628

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  123 YYEPANPTSYVRYATVYQKV-DPDGAVAMLEKLRTVKPDYPV-DAAAGRMYSRNGQLKSAMSHYDKVADPTTIEDYILFD 200
Cdd:TIGR02917 629 ALQPDSALALLLLADAYAVMkNYAKAITSLKRALELKPDNTEaQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL 708

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  201 YALTAYALEEYDKAVSLAQKGIQKYPYYGS---FNRVVLYASDKQKNYPTaveygdklfaATDTVKYTANDY---TYYAD 274
Cdd:TIGR02917 709 EGDLYLRQKDYPAAIQAYRKALKRAPSSQNaikLHRALLASGNTAEAVKT----------LEAWLKTHPNDAvlrTALAE 778

                         250       260
                  ....*....|....*....|....*
gi 495177836  275 ALLNVGRIDDAIKAYKHIPEVAPEN 299
Cdd:TIGR02917 779 LYLAQKDYDKAIKHYQTVVKKAPDN 803
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 68-154 6.41e-05

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 45.84  E-value: 6.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   68 GRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVYQKVDPDGA 147
Cdd:PRK11447  358 GDAALKANNLAQAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPGNTNAVRGLANLYRQQSPEKA 437


                  ....*..
gi 495177836  148 VAMLEKL 154
Cdd:PRK11447  438 LAFIASL 444
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 55-318 6.76e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 6.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   55 KTYKKDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVR 134
Cdd:TIGR02917 595 DAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIG 674

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  135 YATVY-QKVDPDGAVAMLEKLRTVKPDYPV-DAAAGRMYSRNGQLKSAMSHYDKV--ADPT------------------- 191
Cdd:TIGR02917 675 LAQLLlAAKRTESAKKIAKSLQKQHPKAALgFELEGDLYLRQKDYPAAIQAYRKAlkRAPSsqnaiklhrallasgntae 754

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  192 ---TIEDY---------ILFDYALTAYALEEYDKAVSLAQKGIQKYPYygsfNRVVL----YASDKQKNyPTAVEYGDKL 255
Cdd:TIGR02917 755 avkTLEAWlkthpndavLRTALAELYLAQKDYDKAIKHYQTVVKKAPD----NAVVLnnlaWLYLELKD-PRALEYAERA 829

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495177836  256 FAATDTVKYTANDYTYyadALLNVGRIDDAIKAYKHIPEVAPENKEVNKLISDAYLKAKKFDE 318
Cdd:TIGR02917 830 LKLAPNIPAILDTLGW---LLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAE 889
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 22-328 1.87e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.92  E-value: 1.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   22 AQTSQADIDAItkVIVDAKGDAIATKDQVKAFKKTYK-------KDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKS 94
Cdd:TIGR02917 115 GKTLLDDEGAA--ELLALRGLAYLGLGQLELAQKSYEqalaidpRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGN 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   95 AEGYILLGDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATV-----------------------------------Y 139
Cdd:TIGR02917 193 VDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATIlieagefeeaekhadallkkapnsplahylkalvdF 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  140 QKVDPDGAVAMLEKLRTVKPDY-PVDAAAGRMYSRNGQLKSAMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVSLA 218
Cdd:TIGR02917 273 QKKNYEDARETLQDALKSAPEYlPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATL 352

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  219 QKGIQKYPYYGSFNRVVLYASDKQKNYPTAVEYGDKlfaATDTVKYTANDYTYYADALLNVGRIDDAIKAYKHIPEVAPE 298
Cdd:TIGR02917 353 SPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAK---ATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPE 429

                         330       340       350
                  ....*....|....*....|....*....|
gi 495177836  299 NKEVNKLISDAYLKAKKFDESVAAYEAYLA 328
Cdd:TIGR02917 430 LGRADLLLILSYLRSGQFDKALAAAKKLEK 459
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 266-332 1.63e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.13  E-value: 1.63e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495177836 266 ANDYTYYADALLNVGRIDDAIKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAYEAYLAAKGE 332
Cdd:COG3914   78 AALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPD 144
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 22-324 8.02e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.91  E-value: 8.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836   22 AQTSQADIDAitkvivdAKGDAIATKDQVKAFKKTYKKDATAIAALGRAFLEAKNYQMAEEIANLAIKANGKSAEGYILL 101
Cdd:TIGR02917 501 AAANLARIDI-------QEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALAL 573

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  102 GDIASAQDDGGKAAGYYEQGTYYEPANPTSYVRYATVYQKV-DPDGAVAMLEKLRTVKPDYPVD-AAAGRMYSRNGQLKS 179
Cdd:TIGR02917 574 AQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAgDLNKAVSSFKKLLALQPDSALAlLLLADAYAVMKNYAK 653

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495177836  180 AMSHYDKVADPTTIEDYILFDYALTAYALEEYDKAVSLAQKGIQKYPYYGSFNRVVLYASDKQKNYPTAVEYGDKLFAAT 259
Cdd:TIGR02917 654 AITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRA 733

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495177836  260 DtvkyTANDYTYYADALLNVGRIDDAIKAYKHIPEVAPENKEVNKLISDAYLKAKKFDESVAAYE 324
Cdd:TIGR02917 734 P----SSQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQ 794
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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