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Conserved domains on  [gi|495220400|ref|WP_007945175|]
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MULTISPECIES: threonine-phosphate decarboxylase CobD [Pseudomonas]

Protein Classification

threonine-phosphate decarboxylase( domain architecture ID 11490203)

threonine-phosphate decarboxylase is a class I pyridoxal phosphate (PLP)-dependent aminotransferase family protein that catalyzes the decarboxylation of L-threonine-O-3-phosphate to form (R)-1-amino-2-propanol O-2-phosphate, a precursor in cobalamin biosynthesis

CATH:  3.40.640.10
EC:  4.1.1.81
Gene Ontology:  GO:0048472|GO:0009236
PubMed:  11933250|10800595
SCOP:  4000670

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
L_thr_O3P_dcar TIGR01140
L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding ...
 4-321 1.39e-137

L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding class II aminotransferases (see pfamAM:pfam00222) closely related to, yet distinct from, histidinol-phosphate aminotransferase (HisC). It is found in cobalamin biosynthesis operons in Salmonella typhimurium and Bacillus halodurans (each of which also has HisC) and has been shown to have L-threonine-O-3-phosphate decarboxylase activity in Salmonella. Although the gene symbol cobD was assigned in Salmonella, cobD in other contexts refers to a different cobalamin biosynthesis enzyme, modeled by pfam03186 and called cbiB in Salmonella. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


:

Pssm-ID: 273466  Cd Length: 330  Bit Score: 393.10  E-value: 1.39e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400    4 HGGRLRKAAREYGIAEADWLDLSSGLAPWPFPVPDIPLRAWARLPET-GDGLEQAACDYY--SAAQVLPVAGSQMAIQLL 80
Cdd:TIGR01140   1 HGGNLRRAAARYGIPPEDWLDLSTGINPLGPPVPPIPLSAWARYPDPeYDELRAAAAAYYglPAASVLPVNGAQEAIYLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   81 PRLRRAGKVGVLSPCYAEHAEAWRRCGYIVREVLE-QEVDFFIDSLDVLVVVNPNNPTGLSLTPSRLLDWHTRLASRGGW 159
Cdd:TIGR01140  81 PRLLAPGRVLVLAPTYSEYARAWRAAGHEVVELPDlDRLPAALEEADLLVVCNPNNPTGRLIPPETLLALAARLRARGGW 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  160 LVVDEAFMDNTPQLSVAPFTHQV-GLIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSGPTRVIGQACLLDT 238
Cdd:TIGR01140 161 LVVDEAFIDFTPDASLAPQAARFpGLVVLRSLTKFFGLAGLRLGFVVAHPALIARLREALGPWTVNGPALAAGRAALADT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  239 EGHARQRQRSEEASERLARLLEQFGF-KPQGGCALFQWLITEQAERLHVFMARQGILLRLFPHN-----SSLRFGLPADE 312
Cdd:TIGR01140 241 AWQAATRARLAAERARLAALLARLGGlRVVGGTALFLLVRTPDAAALHEALARRGILIRDFDNFpgldpRYLRFALPTDE 320


                  ....*....
gi 495220400  313 aDWTRLAQA 321
Cdd:TIGR01140 321 -ENDRLLEA 328
 
Name Accession Description Interval E-value
L_thr_O3P_dcar TIGR01140
L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding ...
 4-321 1.39e-137

L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding class II aminotransferases (see pfamAM:pfam00222) closely related to, yet distinct from, histidinol-phosphate aminotransferase (HisC). It is found in cobalamin biosynthesis operons in Salmonella typhimurium and Bacillus halodurans (each of which also has HisC) and has been shown to have L-threonine-O-3-phosphate decarboxylase activity in Salmonella. Although the gene symbol cobD was assigned in Salmonella, cobD in other contexts refers to a different cobalamin biosynthesis enzyme, modeled by pfam03186 and called cbiB in Salmonella. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273466  Cd Length: 330  Bit Score: 393.10  E-value: 1.39e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400    4 HGGRLRKAAREYGIAEADWLDLSSGLAPWPFPVPDIPLRAWARLPET-GDGLEQAACDYY--SAAQVLPVAGSQMAIQLL 80
Cdd:TIGR01140   1 HGGNLRRAAARYGIPPEDWLDLSTGINPLGPPVPPIPLSAWARYPDPeYDELRAAAAAYYglPAASVLPVNGAQEAIYLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   81 PRLRRAGKVGVLSPCYAEHAEAWRRCGYIVREVLE-QEVDFFIDSLDVLVVVNPNNPTGLSLTPSRLLDWHTRLASRGGW 159
Cdd:TIGR01140  81 PRLLAPGRVLVLAPTYSEYARAWRAAGHEVVELPDlDRLPAALEEADLLVVCNPNNPTGRLIPPETLLALAARLRARGGW 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  160 LVVDEAFMDNTPQLSVAPFTHQV-GLIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSGPTRVIGQACLLDT 238
Cdd:TIGR01140 161 LVVDEAFIDFTPDASLAPQAARFpGLVVLRSLTKFFGLAGLRLGFVVAHPALIARLREALGPWTVNGPALAAGRAALADT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  239 EGHARQRQRSEEASERLARLLEQFGF-KPQGGCALFQWLITEQAERLHVFMARQGILLRLFPHN-----SSLRFGLPADE 312
Cdd:TIGR01140 241 AWQAATRARLAAERARLAALLARLGGlRVVGGTALFLLVRTPDAAALHEALARRGILIRDFDNFpgldpRYLRFALPTDE 320


                  ....*....
gi 495220400  313 aDWTRLAQA 321
Cdd:TIGR01140 321 -ENDRLLEA 328
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
 18-325 6.99e-82

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 251.59  E-value: 6.99e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  18 AEADWLDLSSGLAPWPFP---VPDIP--LRAWARLPE-TGDGLEQAACDYY--SAAQVLPVAGSQMAIQLLPRLRRA--G 87
Cdd:COG0079   11 EPEDIIKLSSNENPYGPPpkvLEAIAaaLDALNRYPDpDATALREALAEYYgvPPEQVLVGNGSDELIQLLARAFLGpgD 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  88 KVGVLSPCYAEHAEAWRRCGYIVREVLEQEvDFFID----------SLDVLVVVNPNNPTGLSLTPSRLLDWHTRLAsRG 157
Cdd:COG0079   91 EVLVPEPTFSEYPIAARAAGAEVVEVPLDE-DFSLDldallaaiteRTDLVFLCNPNNPTGTLLPREELEALLEALP-AD 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 158 GWLVVDEAFMDNTPQ-LSVAPFTHQV-GLIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSGPTRVIGQACL 235
Cdd:COG0079  169 GLVVVDEAYAEFVPEeDSALPLLARYpNLVVLRTFSKAYGLAGLRLGYAIASPELIAALRRVRGPWNVNSLAQAAALAAL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 236 LDTEGHARQRQRSEEASERLARLLEQFGFKPQGGCALFQWL-ITEQAERLHVFMARQGILLRLFPH---NSSLRFGLPaD 311
Cdd:COG0079  249 EDRAYLEETRARLRAERERLAAALRALGLTVYPSQANFVLVrVPEDAAELFEALLERGILVRDFSSfglPDYLRITVG-T 327

                        330
                 ....*....|....
gi 495220400 312 EADWTRLAQAFETY 325
Cdd:COG0079  328 PEENDRLLAALKEI 341
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 23-323 3.16e-35

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 130.92  E-value: 3.16e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  23 LDLSSGLAPWPFPVP--------DIPLRAWARLPETG-DGLEQAACDYY--------SAAQVLPVAGSQMAIQLLPR-LR 84
Cdd:cd00609    1 IDLSIGEPDFPPPPEvlealaaaALRAGLLGYYPDPGlPELREAIAEWLgrrggvdvPPEEIVVTNGAQEALSLLLRaLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  85 RAG-KVGVLSPCYAEHAEAWRRCGYIVREVLEQEVDFFIDSLD-----------VLVVVNPNNPTGLSLTPSRLLDWHTR 152
Cdd:cd00609   81 NPGdEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLElleaaktpktkLLYLNNPNNPTGAVLSEEELEELAEL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 153 LASRGGWLVVDEAFMDNTPQLSVAPFTHQVG----LIVLRSFGKFFGLAGVRLGFVLAERKLL---NLLAEQVGPWAVSG 225
Cdd:cd00609  161 AKKHGILIISDEAYAELVYDGEPPPALALLDayerVIVLRSFSKTFGLPGLRIGYLIAPPEELlerLKKLLPYTTSGPST 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 226 PTRVIGQACLLDTEGH-ARQRQRSEEASERLARLLEQFGF----KPQGGcaLFQWL------ITEQAERLhvfMARQGIL 294
Cdd:cd00609  241 LSQAAAAAALDDGEEHlEELRERYRRRRDALLEALKELGPlvvvKPSGG--FFLWLdlpegdDEEFLERL---LLEAGVV 315

                        330       340       350
                 ....*....|....*....|....*....|....
gi 495220400 295 LRL-----FPHNSSLRFGLPADEADWTRLAQAFE 323
Cdd:cd00609  316 VRPgsafgEGGEGFVRLSFATPEEELEEALERLA 349
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
20-322 1.44e-27

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 110.09  E-value: 1.44e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   20 ADWLDLSSGlapwpFPVPDIPLRAWARLPETGDG--------------LEQAACDYYS---------AAQVLPVAGSQMA 76
Cdd:pfam00155   1 TDKINLGSN-----EYLGDTLPAVAKAEKDALAGgtrnlygptdghpeLREALAKFLGrspvlkldrEAAVVFGSGAGAN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   77 IQLLPRLRRAGKVGVLS--PCYAEHAEAWRRCGYIVREV-LEQEVDFFID------SLD----VLVVVNPNNPTGLSLTP 143
Cdd:pfam00155  76 IEALIFLLANPGDAILVpaPTYASYIRIARLAGGEVVRYpLYDSNDFHLDfdaleaALKekpkVVLHTSPHNPTGTVATL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  144 SRLLDWHTRLASRGGWLVVDEAFMDNTPQLSVAPFTHQ-----VGLIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQV 218
Cdd:pfam00155 156 EELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRAllaegPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQLRKLA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  219 GPWAVSGPTRVIGQACLLDTEGHARQ----RQRSEEASERLARLLEQFGFKPQGGC-ALFQWLITEQA----------ER 283
Cdd:pfam00155 236 RPFYSSTHLQAAAAAALSDPLLVASEleemRQRIKERRDYLRDGLQAAGLSVLPSQaGFFLLTGLDPEtakelaqvllEE 315

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 495220400  284 LHVFMARQGIllrlFPHNSSLRFGLPA-DEADWTRLAQAF 322
Cdd:pfam00155 316 VGVYVTPGSS----PGVPGWLRITVAGgTEEELEELLEAI 351
PRK07908 PRK07908
threonine-phosphate decarboxylase;
45-319 5.01e-26

threonine-phosphate decarboxylase;


Pssm-ID: 236128  Cd Length: 349  Bit Score: 105.86  E-value: 5.01e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  45 ARLPETGDGLE--QAACDYY--SAAQVLPVAGSQMAIQLLPRLRRAGKVgVLSPCYAEHAEAWRRCGYIVREVLeQEVDF 120
Cdd:PRK07908  52 AAYPSTEDERRarAAVAARHgrTPDEVLLLAGAAEGFALLARLRPRRAA-VVHPSFTEPEAALRAAGIPVHRVV-LDPPF 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 121 FIDSLDV-----LVVV-NPNNPTGLsLTPSRLLdwhTRLASRGGWLVVDEAFMDNTP--QLSVAPfTHQVGLIVLRSFGK 192
Cdd:PRK07908 130 RLDPAAVpddadLVVIgNPTNPTSV-LHPAEQL---LALRRPGRILVVDEAFADAVPgePESLAG-DDLPGVLVLRSLTK 204

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 193 FFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSGPTRVIGQAClLDTEGHARQRQRSEEAS---ERLARLLEQFGFKP-QG 268
Cdd:PRK07908 205 TWSLAGLRVGYALGAPDVLARLTRGRAHWPVGTLQLEAIAAC-CAPRAVAEAAADAARLAadrAEMVAGLRAVGARVvDP 283

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 495220400 269 GCALFQWLITEQAERLHVFMARQGILLR---LFPhnsslrfGLpadEADWTRLA 319
Cdd:PRK07908 284 AAAPFVLVRVPDAELLRKRLRERGIAVRrgdTFP-------GL---DPDYLRLA 327
GntC_guanitoxin NF041364
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;
62-211 1.71e-09

guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;


Pssm-ID: 469255  Cd Length: 354  Bit Score: 58.12  E-value: 1.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  62 YSAAQVLPVAGSQMAIQLL--PRLRRAGKVGVLSPCYAEHAEAWRRCGYIVREV-LEQEVDFFIDSLD-----------V 127
Cdd:NF041364  58 VSPDQVLVTTGASEALFLYfhALLEPGDEVVVPVPAFQSLYEVPELLGGRVRPLpLSPENQGFRPDLEalrslitprtrA 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 128 LVVVNPNNPTGLSLTP---SRLLDwhtrLASR-GGWLVVDEAF----MDNTPQLSVAPFTH-QVGLIVLRSFGKFFGLAG 198
Cdd:NF041364 138 IVINSPNNPTGAVMTEaelEAILE----IASRhGLIVLADEHYrflpYDDGKHVSPSLYPGlSERVIALGSFSKTYGMTG 213

                        170
                 ....*....|...
gi 495220400 199 VRLGFVLAERKLL 211
Cdd:NF041364 214 LRVGWLIGPKELI 226
 
Name Accession Description Interval E-value
L_thr_O3P_dcar TIGR01140
L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding ...
 4-321 1.39e-137

L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding class II aminotransferases (see pfamAM:pfam00222) closely related to, yet distinct from, histidinol-phosphate aminotransferase (HisC). It is found in cobalamin biosynthesis operons in Salmonella typhimurium and Bacillus halodurans (each of which also has HisC) and has been shown to have L-threonine-O-3-phosphate decarboxylase activity in Salmonella. Although the gene symbol cobD was assigned in Salmonella, cobD in other contexts refers to a different cobalamin biosynthesis enzyme, modeled by pfam03186 and called cbiB in Salmonella. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273466  Cd Length: 330  Bit Score: 393.10  E-value: 1.39e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400    4 HGGRLRKAAREYGIAEADWLDLSSGLAPWPFPVPDIPLRAWARLPET-GDGLEQAACDYY--SAAQVLPVAGSQMAIQLL 80
Cdd:TIGR01140   1 HGGNLRRAAARYGIPPEDWLDLSTGINPLGPPVPPIPLSAWARYPDPeYDELRAAAAAYYglPAASVLPVNGAQEAIYLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   81 PRLRRAGKVGVLSPCYAEHAEAWRRCGYIVREVLE-QEVDFFIDSLDVLVVVNPNNPTGLSLTPSRLLDWHTRLASRGGW 159
Cdd:TIGR01140  81 PRLLAPGRVLVLAPTYSEYARAWRAAGHEVVELPDlDRLPAALEEADLLVVCNPNNPTGRLIPPETLLALAARLRARGGW 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  160 LVVDEAFMDNTPQLSVAPFTHQV-GLIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSGPTRVIGQACLLDT 238
Cdd:TIGR01140 161 LVVDEAFIDFTPDASLAPQAARFpGLVVLRSLTKFFGLAGLRLGFVVAHPALIARLREALGPWTVNGPALAAGRAALADT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  239 EGHARQRQRSEEASERLARLLEQFGF-KPQGGCALFQWLITEQAERLHVFMARQGILLRLFPHN-----SSLRFGLPADE 312
Cdd:TIGR01140 241 AWQAATRARLAAERARLAALLARLGGlRVVGGTALFLLVRTPDAAALHEALARRGILIRDFDNFpgldpRYLRFALPTDE 320


                  ....*....
gi 495220400  313 aDWTRLAQA 321
Cdd:TIGR01140 321 -ENDRLLEA 328
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
 18-325 6.99e-82

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 251.59  E-value: 6.99e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  18 AEADWLDLSSGLAPWPFP---VPDIP--LRAWARLPE-TGDGLEQAACDYY--SAAQVLPVAGSQMAIQLLPRLRRA--G 87
Cdd:COG0079   11 EPEDIIKLSSNENPYGPPpkvLEAIAaaLDALNRYPDpDATALREALAEYYgvPPEQVLVGNGSDELIQLLARAFLGpgD 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  88 KVGVLSPCYAEHAEAWRRCGYIVREVLEQEvDFFID----------SLDVLVVVNPNNPTGLSLTPSRLLDWHTRLAsRG 157
Cdd:COG0079   91 EVLVPEPTFSEYPIAARAAGAEVVEVPLDE-DFSLDldallaaiteRTDLVFLCNPNNPTGTLLPREELEALLEALP-AD 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 158 GWLVVDEAFMDNTPQ-LSVAPFTHQV-GLIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSGPTRVIGQACL 235
Cdd:COG0079  169 GLVVVDEAYAEFVPEeDSALPLLARYpNLVVLRTFSKAYGLAGLRLGYAIASPELIAALRRVRGPWNVNSLAQAAALAAL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 236 LDTEGHARQRQRSEEASERLARLLEQFGFKPQGGCALFQWL-ITEQAERLHVFMARQGILLRLFPH---NSSLRFGLPaD 311
Cdd:COG0079  249 EDRAYLEETRARLRAERERLAAALRALGLTVYPSQANFVLVrVPEDAAELFEALLERGILVRDFSSfglPDYLRITVG-T 327

                        330
                 ....*....|....
gi 495220400 312 EADWTRLAQAFETY 325
Cdd:COG0079  328 PEENDRLLAALKEI 341
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 23-323 3.16e-35

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 130.92  E-value: 3.16e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  23 LDLSSGLAPWPFPVP--------DIPLRAWARLPETG-DGLEQAACDYY--------SAAQVLPVAGSQMAIQLLPR-LR 84
Cdd:cd00609    1 IDLSIGEPDFPPPPEvlealaaaALRAGLLGYYPDPGlPELREAIAEWLgrrggvdvPPEEIVVTNGAQEALSLLLRaLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  85 RAG-KVGVLSPCYAEHAEAWRRCGYIVREVLEQEVDFFIDSLD-----------VLVVVNPNNPTGLSLTPSRLLDWHTR 152
Cdd:cd00609   81 NPGdEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLElleaaktpktkLLYLNNPNNPTGAVLSEEELEELAEL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 153 LASRGGWLVVDEAFMDNTPQLSVAPFTHQVG----LIVLRSFGKFFGLAGVRLGFVLAERKLL---NLLAEQVGPWAVSG 225
Cdd:cd00609  161 AKKHGILIISDEAYAELVYDGEPPPALALLDayerVIVLRSFSKTFGLPGLRIGYLIAPPEELlerLKKLLPYTTSGPST 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 226 PTRVIGQACLLDTEGH-ARQRQRSEEASERLARLLEQFGF----KPQGGcaLFQWL------ITEQAERLhvfMARQGIL 294
Cdd:cd00609  241 LSQAAAAAALDDGEEHlEELRERYRRRRDALLEALKELGPlvvvKPSGG--FFLWLdlpegdDEEFLERL---LLEAGVV 315

                        330       340       350
                 ....*....|....*....|....*....|....
gi 495220400 295 LRL-----FPHNSSLRFGLPADEADWTRLAQAFE 323
Cdd:cd00609  316 VRPgsafgEGGEGFVRLSFATPEEELEEALERLA 349
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
20-322 1.44e-27

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 110.09  E-value: 1.44e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   20 ADWLDLSSGlapwpFPVPDIPLRAWARLPETGDG--------------LEQAACDYYS---------AAQVLPVAGSQMA 76
Cdd:pfam00155   1 TDKINLGSN-----EYLGDTLPAVAKAEKDALAGgtrnlygptdghpeLREALAKFLGrspvlkldrEAAVVFGSGAGAN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   77 IQLLPRLRRAGKVGVLS--PCYAEHAEAWRRCGYIVREV-LEQEVDFFID------SLD----VLVVVNPNNPTGLSLTP 143
Cdd:pfam00155  76 IEALIFLLANPGDAILVpaPTYASYIRIARLAGGEVVRYpLYDSNDFHLDfdaleaALKekpkVVLHTSPHNPTGTVATL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  144 SRLLDWHTRLASRGGWLVVDEAFMDNTPQLSVAPFTHQ-----VGLIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQV 218
Cdd:pfam00155 156 EELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRAllaegPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQLRKLA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  219 GPWAVSGPTRVIGQACLLDTEGHARQ----RQRSEEASERLARLLEQFGFKPQGGC-ALFQWLITEQA----------ER 283
Cdd:pfam00155 236 RPFYSSTHLQAAAAAALSDPLLVASEleemRQRIKERRDYLRDGLQAAGLSVLPSQaGFFLLTGLDPEtakelaqvllEE 315

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 495220400  284 LHVFMARQGIllrlFPHNSSLRFGLPA-DEADWTRLAQAF 322
Cdd:pfam00155 316 VGVYVTPGSS----PGVPGWLRITVAGgTEEELEELLEAI 351
PRK07908 PRK07908
threonine-phosphate decarboxylase;
45-319 5.01e-26

threonine-phosphate decarboxylase;


Pssm-ID: 236128  Cd Length: 349  Bit Score: 105.86  E-value: 5.01e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  45 ARLPETGDGLE--QAACDYY--SAAQVLPVAGSQMAIQLLPRLRRAGKVgVLSPCYAEHAEAWRRCGYIVREVLeQEVDF 120
Cdd:PRK07908  52 AAYPSTEDERRarAAVAARHgrTPDEVLLLAGAAEGFALLARLRPRRAA-VVHPSFTEPEAALRAAGIPVHRVV-LDPPF 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 121 FIDSLDV-----LVVV-NPNNPTGLsLTPSRLLdwhTRLASRGGWLVVDEAFMDNTP--QLSVAPfTHQVGLIVLRSFGK 192
Cdd:PRK07908 130 RLDPAAVpddadLVVIgNPTNPTSV-LHPAEQL---LALRRPGRILVVDEAFADAVPgePESLAG-DDLPGVLVLRSLTK 204

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 193 FFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSGPTRVIGQAClLDTEGHARQRQRSEEAS---ERLARLLEQFGFKP-QG 268
Cdd:PRK07908 205 TWSLAGLRVGYALGAPDVLARLTRGRAHWPVGTLQLEAIAAC-CAPRAVAEAAADAARLAadrAEMVAGLRAVGARVvDP 283

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 495220400 269 GCALFQWLITEQAERLHVFMARQGILLR---LFPhnsslrfGLpadEADWTRLA 319
Cdd:PRK07908 284 AAAPFVLVRVPDAELLRKRLRERGIAVRrgdTFP-------GL---DPDYLRLA 327
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
 11-255 7.84e-22

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 94.26  E-value: 7.84e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   11 AAREYGIAEADWLDLSSGlapwPFPVPDIPLRAWA-------RLPE-TGDGLEQAACDYY--SAAQVLPVAGSQMAIQLL 80
Cdd:TIGR01141  13 GARELGGDEVIKLNSNEN----PFGPPEKAKEALRaelkklhRYPDpDPAELKQALADYYgvDPEQILLGNGSDEIIDLL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   81 PR--LRRAGKVGVLSPCYAEHAEAWRRCGYIVREVlEQEVDFFIDSLDVLVVV----------NPNNPTGLSLTPSRLLD 148
Cdd:TIGR01141  89 IRafLEPGDAVLVPPPTYSMYEISAKIHGAEVVKV-PLDEDGQLDLEDILVAIddkpklvflcSPNNPTGNLFSRGDIEA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  149 WHTRLASRgGWLVVDEAFMDNTPQLSVAPFTHQV-GLIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSGPT 227
Cdd:TIGR01141 168 VLERTPGD-ALVVVDEAYGEFSGEPSTLPLLAEYpNLIVLRTLSKAFGLAGLRIGYAIANAEIIDALNKVRAPFNLSRLA 246

                         250       260
                  ....*....|....*....|....*...
gi 495220400  228 RVIGQACLLDTEGHARQRQRSEEASERL 255
Cdd:TIGR01141 247 QAAAIAALRDDDFIEATVEEINAERERL 274
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 7-276 4.33e-19

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 87.11  E-value: 4.33e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   7 RLRKAAREYGIAEADWLDLSSGlAPwPFPVPDIPLRAWARLPETG-------DGLE---QAACDYY--------SAAQVL 68
Cdd:COG0436   17 EVSALAAELKAAGEDVIDLGIG-EP-DFPTPDHIREAAIEALDDGvtgytpsAGIPelrEAIAAYYkrrygvdlDPDEIL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  69 PVAGSQMAIQLLPR-LRRAG-KVGVLSPCYAEHAEAWRRCGYIVREV-LEQEVDFFIDsLD-----------VLVVVNPN 134
Cdd:COG0436   95 VTNGAKEALALALLaLLNPGdEVLVPDPGYPSYRAAVRLAGGKPVPVpLDEENGFLPD-PEaleaaitprtkAIVLNSPN 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 135 NPTGLSLTPS---RLLDWhtrLASRGGWLVVDEAF----MDNTPQLSVA--PFTHQVGlIVLRSFGKFFGLAGVRLGFVL 205
Cdd:COG0436  174 NPTGAVYSREeleALAEL---AREHDLLVISDEIYeelvYDGAEHVSILslPGLKDRT-IVINSFSKSYAMTGWRIGYAV 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 206 AERKL---LNLLAEQVgpwaVSGPTRVI---GQACLLDTEGH-ARQRQRSEEASERLARLLEQFGF---KPQGgcALFQW 275
Cdd:COG0436  250 GPPELiaaLLKLQSNL----TSCAPTPAqyaAAAALEGPQDYvEEMRAEYRRRRDLLVEGLNEIGLsvvKPEG--AFYLF 323


                 .
gi 495220400 276 L 276
Cdd:COG0436  324 A 324
PRK09105 PRK09105
pyridoxal phosphate-dependent aminotransferase;
127-294 6.91e-18

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181651  Cd Length: 370  Bit Score: 83.17  E-value: 6.91e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 127 VLVVVNPNNPTGlSLTPSRLLDWHTRLASRGGWLVVDEAFMDNTPQLSVAPFTHQ-VGLIVLRSFGKFFGLAGVRLGFVL 205
Cdd:PRK09105 168 LIYICNPNNPTG-TVTPRADIEWLLANKPAGSVLLVDEAYIHFSDAPSVVDLVAQrKDLIVLRTFSKLYGMAGMRLGLAA 246

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 206 AERKLLNLLAEQvGPWAVSGPTRVIGQACLLDTEGHARQRQRSEEASERLARLLEQFGFK---PQGGCALFQWliTEQAE 282
Cdd:PRK09105 247 ARPDLLAKLARF-GHNPLPVPAAAAGLASLRDPKLVPQRRAENAAVREDTIAWLKKKGYKctpSQANCFMVDV--KRPAK 323

                        170
                 ....*....|..
gi 495220400 283 RLHVFMARQGIL 294
Cdd:PRK09105 324 AVADAMAKQGVF 335
PRK08354 PRK08354
putative aminotransferase; Provisional
 16-323 1.06e-16

putative aminotransferase; Provisional


Pssm-ID: 169399  Cd Length: 311  Bit Score: 79.39  E-value: 1.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  16 GIAEADWLDLSSGLAPWPfpvPDIPLRAWARLPETG------DGLEQAACDYYSAAQVLpVAGSQMAIQLLPRLR-RAGK 88
Cdd:PRK08354   4 GIREEGLIDFSASVNPYP---PEWLDEMFERAKEISgrytyyEWLEEEFSKLFGEPIVI-TAGITEALYLIGILAlRDRK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  89 VGVLSPCYAEHAEAWRRCGYIVR------EVLEQevdfFIDSLDVLVVVNPNNPTGLSLTPSRLLDWHTRLASRGGWLVV 162
Cdd:PRK08354  80 VIIPRHTYGEYERVARFFAARIIkgpndpEKLEE----LVERNSVVFFCNPNNPDGKFYNFKELKPLLDAVEDRNALLIL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 163 DEAFMDNTPQLSVAPFTHqvgLIVLRSFGKFFGLAGVRLGFVLAERKLLnllaEQV-GPWAVSGPTRVIGQACLLDTEGH 241
Cdd:PRK08354 156 DEAFIDFVKKPESPEGEN---IIKLRTFTKSYGLPGIRVGYVKGFEEAF----RSVrMPWSIGSTGYAFLEFLIEDDFEH 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 242 ARqrqRSEEASERLARLLEQF-GFKPQggcALFQWLITEQAERLHVFMARQGILLRL---FPHNSSLRFGLPADEADwTR 317
Cdd:PRK08354 229 LR---KTMPLIWREKERFEKAlYVKSD---ANFFIKDVGDAEKFVEFLKRNGILVRDctsFGLPGYIRFSVRDREEN-EK 301


                 ....*.
gi 495220400 318 LAQAFE 323
Cdd:PRK08354 302 LIRALR 307
PRK06425 PRK06425
histidinol-phosphate aminotransferase; Validated
 1-297 4.00e-15

histidinol-phosphate aminotransferase; Validated


Pssm-ID: 102370  Cd Length: 332  Bit Score: 74.89  E-value: 4.00e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   1 MLEHGGRLRKAAREYGiaeaDWLDLSSGLAPWpfpvpdIPLRAWARLPETGDGLEQAACDYYSAA---QVLPVAGSQMAI 77
Cdd:PRK06425   1 MRGHGGDVYEASSKYG----RIIDFSANINDF------MDIGDISIYPEISYTDIEDQIKIYTQGlkiKVLIGPGLTHFI 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  78 QLLPRLRRAGKVGVLSPCYAEH---AEAWR-RCGYIVREVLEQEVDFFID-SLDVLVVVNPNNPTGLSLTPSRLLDWHTR 152
Cdd:PRK06425  71 YRLLSYINVGNIIIVEPNFNEYkgyAFTHGiRISALPFNLINNNPEILNNyNFDLIFIVSPDNPLGNLISRDSLLTISEI 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 153 LASRGGWLVVDEAFMDNTP-------QLSVAPFTHQVGlivlRSFGKFFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSG 225
Cdd:PRK06425 151 CRKKGALLFIDEAFIDFVPnraeedvLLNRSYGNVIIG----RSLTKILGIPSLRIGYIATDDYNMKISRKITEPWSVCD 226

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 495220400 226 PT-RVIGQACLLDTEGHARQRQRSEEasERLARLLEQFGFKPQGG-CALFQWLITEQAERLHVFMARQGILLRL 297
Cdd:PRK06425 227 PAiDFIRSIDLDYVAKHSLDIMENER--SYLINNLEAMGFRAAGDpSANFITFMIPDAHDFYSYLLKNGILVRL 298
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 13-308 4.73e-14

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 72.55  E-value: 4.73e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  13 REYGIAEADWLDLSSGlapwpFPVPD-IPLRAWARL----------------PETGD-GLEQAACDYY-------SAAQV 67
Cdd:COG1167   99 RRLLEAAPGVIDLGSG-----APDPDlFPLAALRRAlrralrrlppallgygDPQGLpELREAIARYLarrgvpaSPDQI 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  68 LPVAGSQMAIQLLPR-LRRAG-KVGVLSPCYAEHAEAWRRCGYIVREV--LEQEVDffIDSLDV--------LVVVNPN- 134
Cdd:COG1167  174 LITSGAQQALDLALRaLLRPGdTVAVESPTYPGALAALRAAGLRLVPVpvDEDGLD--LDALEAalrrhrprAVYVTPSh 251

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 135 -NPTGLSLTPSR---LLDWhtrLASRGGWLVVDEAF----MDNTPQLSVAPFTHQVGLIVLRSFGKFFGlAGVRLGFVLA 206
Cdd:COG1167  252 qNPTGATMSLERrraLLEL---ARRHGVPIIEDDYDselrYDGRPPPPLAALDAPGRVIYIGSFSKTLA-PGLRLGYLVA 327

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 207 ERKLLNLLAEQVGPWAVSGPtrVIGQACLLD--TEGHA-----RQRQRSEEASERLARLLEQ-FG-----FKPQGGcaLF 273
Cdd:COG1167  328 PGRLIERLARLKRATDLGTS--PLTQLALAEflESGHYdrhlrRLRREYRARRDLLLAALARhLPdglrvTGPPGG--LH 403

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 495220400 274 QWLITEQ---AERLHVFMARQGILLR---LF----PHNSSLRFGL 308
Cdd:COG1167  404 LWLELPEgvdAEALAAAALARGILVApgsAFsadgPPRNGLRLGF 448
PLN03026 PLN03026
histidinol-phosphate aminotransferase; Provisional
 109-296 6.83e-13

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 178597  Cd Length: 380  Bit Score: 68.57  E-value: 6.83e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 109 IVREVLEQEVDffidsldVLVVVNPNNPTGLSLTPSRLLdwhtRLASRGGWLVVDEAFMDNTPQLSvapFTHQV----GL 184
Cdd:PLN03026 167 IVEAVETHKPK-------LLFLTSPNNPDGSIISDDDLL----KILELPILVVLDEAYIEFSTQES---RMKWVkkydNL 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 185 IVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQVGPWAVSGPTRVIGQACL-----LDTEGHARQRQRseeasERLARLL 259
Cdd:PLN03026 233 IVLRTFSKRAGLAGLRVGYGAFPLSIIEYLWRAKQPYNVSVAAEVAACAALsnpkyLEDVKNALVEER-----ERLFGLL 307

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 495220400 260 EQFGF-KPQGGCA---LFQWLITEQAERLHVFMARQGILLR 296
Cdd:PLN03026 308 KEVPFlEPYPSDAnfiLCRVTSGRDAKKLKEDLAKMGVMVR 348
PRK03321 PRK03321
putative aminotransferase; Provisional
 130-299 5.41e-11

putative aminotransferase; Provisional


Pssm-ID: 179559  Cd Length: 352  Bit Score: 62.68  E-value: 5.41e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 130 VVNPNNPTGLSLTPSRLLDWHTRLASRggWLVV-DEAFM-----DNTPqLSVAPFTHQVGLIVLRSFGKFFGLAGVRLGF 203
Cdd:PRK03321 151 VCNPNNPTGTVVTPAELARFLDAVPAD--VLVVlDEAYVeyvrdDDVP-DGLELVRDHPNVVVLRTFSKAYGLAGLRVGY 227

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 204 VLAERKLLNLLAEQVGPWAVSGPTRVIGQACL--LD-----TEGHARQRQRSEEAserlarLLEQfGFKPQGGCALFQWL 276
Cdd:PRK03321 228 AVGHPEVIAALRKVAVPFSVNSLAQAAAIASLaaEDellerVDAVVAERDRVRAA------LRAA-GWTVPPSQANFVWL 300

                        170       180
                 ....*....|....*....|....
gi 495220400 277 IT-EQAERLHVFMARQGILLRLFP 299
Cdd:PRK03321 301 PLgERTADFAAAAAEAGVVVRPFA 324
PRK05166 PRK05166
histidinol-phosphate transaminase;
72-273 3.68e-10

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 60.54  E-value: 3.68e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  72 GSQMAIQLLPR--LRRAGKVGVLSPCYAEHAEAWRRCGYIVREV-----LEQEVDFFIDSL----DVLVVVNPNNPTGLS 140
Cdd:PRK05166  96 GSEDLIAVICRavLRPGDRVVTLYPSFPLHEDYPTMMGARVERVtvtpdLGFDLDALCAAVarapRMLMFSNPSNPVGSW 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 141 LTP---SRLLDwhtrLASRGGWLVVDEAFM-----DNTPqlSVAPFTHQVGL--IVLRSFGKFFGLAGVRLGFVLA-ERK 209
Cdd:PRK05166 176 LTAdqlARVLD----ATPPETLIVVDEAYAeyaagDDYP--SALTLLKARGLpwIVLRTFSKAYGLAGLRVGYGLVsDPE 249

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 495220400 210 LLNLLAEQVGPWAVSGPTRVIGQACLLDTEGHARQRQRSEEASERLARLLEQFGFK--PQGGCALF 273
Cdd:PRK05166 250 LVGLLDRVRTPFNVNGAAQAAALAALDDEEHLAKGVALALAERERLKKELAEMGYRiaPSRANFLF 315
GntC_guanitoxin NF041364
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;
62-211 1.71e-09

guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;


Pssm-ID: 469255  Cd Length: 354  Bit Score: 58.12  E-value: 1.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  62 YSAAQVLPVAGSQMAIQLL--PRLRRAGKVGVLSPCYAEHAEAWRRCGYIVREV-LEQEVDFFIDSLD-----------V 127
Cdd:NF041364  58 VSPDQVLVTTGASEALFLYfhALLEPGDEVVVPVPAFQSLYEVPELLGGRVRPLpLSPENQGFRPDLEalrslitprtrA 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 128 LVVVNPNNPTGLSLTP---SRLLDwhtrLASR-GGWLVVDEAF----MDNTPQLSVAPFTH-QVGLIVLRSFGKFFGLAG 198
Cdd:NF041364 138 IVINSPNNPTGAVMTEaelEAILE----IASRhGLIVLADEHYrflpYDDGKHVSPSLYPGlSERVIALGSFSKTYGMTG 213

                        170
                 ....*....|...
gi 495220400 199 VRLGFVLAERKLL 211
Cdd:NF041364 214 LRVGWLIGPKELI 226
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
106-218 3.99e-09

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 57.07  E-value: 3.99e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 106 CGY-IVREVLEQEVDffiDSLDVLVVVNPNNPTGLSLTPSRLLDWHTRLASRGGWLVVDEAFMD----NTPQLSVAPfth 180
Cdd:PRK06225 141 CNYkLTPELVKENMD---ENTRLIYLIDPLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRDfareHTLAAEYAP--- 214

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 495220400 181 qVGLIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEQV 218
Cdd:PRK06225 215 -EHTVTSYSFSKIFGMAGLRIGAVVATPDLIEVVKSIV 251
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
128-206 5.34e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 53.90  E-value: 5.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 128 LVVVNPNNPTGLSLTPSRLLDWHTRLASRGGWLVVDEAFMDNTPQLSvAPFTHQVG--LIVLRSFGKFFGLAGVRLGFVL 205
Cdd:PRK08960 169 ALVASPANPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYGVD-AASVLEVDddAFVLNSFSKYFGMTGWRLGWLV 247


                 .
gi 495220400 206 A 206
Cdd:PRK08960 248 A 248
PRK07550 PRK07550
aminotransferase;
128-211 1.21e-07

aminotransferase;


Pssm-ID: 181026 [Multi-domain]  Cd Length: 386  Bit Score: 52.65  E-value: 1.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 128 LVVVNPNNPTGLSLTPSRLLDWHTRLASRGGWLVVDEAFMDNTPQlSVAP---FTH---QVGLIVLRSFGKFFGLAGVRL 201
Cdd:PRK07550 167 IALVTPNNPTGVVYPPELLHELYDLARRHGIALILDETYRDFDSG-GGAPhdlFADpdwDDTLVHLYSFSKSYALTGHRV 245

                         90
                 ....*....|
gi 495220400 202 GFVLAERKLL 211
Cdd:PRK07550 246 GAVVASPARI 255
PRK02610 PRK02610
histidinol-phosphate transaminase;
127-323 1.81e-06

histidinol-phosphate transaminase;


Pssm-ID: 235053  Cd Length: 374  Bit Score: 48.94  E-value: 1.81e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 127 VLVVVNPNNPTGLSLTpSRLLDWHTRLASRGgWLVVDEAFMDNTPQLSVAPFTHQVGLIVLRSFGKFFGLAGVRLGFVLA 206
Cdd:PRK02610 171 VVFVVHPNSPTGNPLT-AAELEWLRSLPEDI-LVVIDEAYFEFSQTTLVGELAQHPNWVILRTFSKAFRLAAHRVGYAIG 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 207 ERKLLNLLAEQVGPWAVSGPTRVIGQACLldteghaRQRQRSEEA-----SERlARLLEQFGFKPQGGCA------LFQW 275
Cdd:PRK02610 249 HPELIAVLEKVRLPYNLPSFSQLAAQLAL-------EHRQELLAAipeilQER-DRLYQALQELPQLRVWpsaanfLYLR 320

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 495220400 276 LITEQA-ERLHVFMARQGILLRLFPHNSSLRFGLPAD-EADWTRLAQAFE 323
Cdd:PRK02610 321 LSQDAAlAALHQALKAQGTLVRHTGGGLRITIGTPEEnQRTLERLQAALT 370
PRK03317 PRK03317
histidinol-phosphate aminotransferase; Provisional
 126-206 5.72e-06

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 235115  Cd Length: 368  Bit Score: 47.55  E-value: 5.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 126 DVLVVVNPNNPTGLSLTPS---RLLDwhtrlaSRGGWLVVDEAFM----DNTPQ----LSVAPfthqvGLIVLRSFGKFF 194
Cdd:PRK03317 162 DVVFLTSPNNPTGTALPLDdveAILD------AAPGIVVVDEAYAefrrSGTPSaltlLPEYP-----RLVVSRTMSKAF 230

                         90
                 ....*....|..
gi 495220400 195 GLAGVRLGFVLA 206
Cdd:PRK03317 231 AFAGGRLGYLAA 242
PRK15481 PRK15481
transcriptional regulatory protein PtsJ; Provisional
 24-296 9.26e-06

transcriptional regulatory protein PtsJ; Provisional


Pssm-ID: 185378 [Multi-domain]  Cd Length: 431  Bit Score: 46.96  E-value: 9.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  24 DLSSGlAPWPFPVPDIPlRAWARLPET----GD-----GLEQAACDYYSAAqvLPVA-------GSQMAIQ-LLPRLRRA 86
Cdd:PRK15481  89 DLAGG-NPDPQRLPDLS-RYFARLSRTprlyGDapvspELHAWAARWLRDD--CPVAfeidltsGAIDAIErLLCAHLLP 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  87 G-KVGVLSPCYAEHAEAWRRCGYivrEVLEQEVD---FFIDSLD---------VLVVVNPNNPTGLSLTPSRLLDWHTRL 153
Cdd:PRK15481 165 GdSVAVEDPCFLSSINMLRYAGF---SASPVSVDaegMQPEKLEralaqgaraVILTPRAHNPTGCSLSARRAAALRNLL 241

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 154 ASRGGWLV-VDEAFmdntPQLSVAPFTHQVGL-----IVLRSFGKFFGlAGVRLGFV---LAERKLLNLLAEQVGPWaVS 224
Cdd:PRK15481 242 ARYPQVLViIDDHF----ALLSSSPYHSVIPQttqrwALIRSVSKALG-PDLRLAFVasdSATSARLRLRLNSGTQW-VS 315

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495220400 225 GPTRVIGQACLLDTEGHAR---QRQRSEEASERLARLLEQFGFK-PQGGCALFQWLITEQAERLHVF-MARQGILLR 296
Cdd:PRK15481 316 HLLQDLVYACLTDPEYQARlaqARLFYAQRRQKLARALQQYGIAiPSPGDGLNLWLPLDTDSQATALtLAKSGWLVR 392
PRK07337 PRK07337
pyridoxal phosphate-dependent aminotransferase;
133-206 1.40e-05

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180937  Cd Length: 388  Bit Score: 46.21  E-value: 1.40e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495220400 133 PNNPTGLSLTPSRLLDWHTRLASRGGWLVVDEAFM----DNTPQLSVApftHQVGLIVLRSFGKFFGLAGVRLGFVLA 206
Cdd:PRK07337 172 PSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQglsyDAAPVSALS---LGDDVITINSFSKYFNMTGWRLGWLVV 246
PRK08361 PRK08361
aspartate aminotransferase; Provisional
 45-275 1.80e-05

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 46.02  E-value: 1.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  45 ARLPEtgdgLEQAACDYY--------SAAQVLPVAGSQMAIQLL--PRLRRAGKVGVLSP---CYAEHAEAWRrcGYIVR 111
Cdd:PRK08361  70 AGIPE----LREAIAEYYkkfygvdvDVDNVIVTAGAYEATYLAfeSLLEEGDEVIIPDPafvCYVEDAKIAE--AKPIR 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 112 EVLEQEVDFFIDSLDVL---------VVVN-PNNPTGLSLtpsrllDWHTRLAsrggwlVVDEAFMDNTPQLSVAPFTHQ 181
Cdd:PRK08361 144 IPLREENEFQPDPDELLelitkrtrmIVINyPNNPTGATL------DKEVAKA------IADIAEDYNIYILSDEPYEHF 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 182 V---------------GLIVLRSFGKFFGLAGVRLGFVLAE----RKLLNLLAEQVGpwAVSGPTRVIGQACLLDTEG-H 241
Cdd:PRK08361 212 LyegakhypmikyapdNTILANSFSKTFAMTGWRLGFVIAPeqviKDMIKLHAYIIG--NVASFVQIAGIEALRSKESwK 289

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 495220400 242 ARQRQRSEEASER---LARLLEQFG---FKPQGgcALFQW 275
Cdd:PRK08361 290 AVEEMRKEYNERRklvLKRLKEMPHikvFEPKG--AFYVF 327
PRK08153 PRK08153
pyridoxal phosphate-dependent aminotransferase;
132-266 2.41e-05

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181255  Cd Length: 369  Bit Score: 45.37  E-value: 2.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 132 NPNNPTGLSLTPSRLLDWHTRLASrGGWLVVDEAFMDNTPQLSVAPF-THQVGLIVLRSFGKFFGLAGVRLGFVLAERKL 210
Cdd:PRK08153 163 NPDNPMGSWHPAADIVAFIEALPE-TTLLVLDEAYCETAPAGAAPPIdTDDPNVIRMRTFSKAYGLAGARVGYAIGAPGT 241

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 495220400 211 LNLLAEQVGPWAVSGPTRVIGQACLLDTEGHARQRQRSEEASERLARLLEQFGFKP 266
Cdd:PRK08153 242 IKAFDKVRNHFGMNRIAQAAALAALKDQAYLAEVVGKIAAARDRIAAIARANGLTP 297
avtA PRK09440
valine--pyruvate transaminase; Provisional
 117-276 1.11e-04

valine--pyruvate transaminase; Provisional


Pssm-ID: 236517  Cd Length: 416  Bit Score: 43.69  E-value: 1.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 117 EVDFfiDSLDV------LVVVNPNNPTGLSLTPSRL--LDwhtRLASRGGW-LVVDEAFMDNTPQL---SVAPFTHQvGL 184
Cdd:PRK09440 168 HVDF--EHLHIdedtgaICVSRPTNPTGNVLTDEELekLD---ALARQHNIpLLIDNAYGPPFPGIifsEATPLWNP-NI 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 185 IVLRSFGKFfGLAGVRLGFVLAERKLLNLLAEQVGPWAVSgPTRvIGQACLL------DTEGHARQ------RQRSEEAS 252
Cdd:PRK09440 242 ILCMSLSKL-GLPGVRCGIVIADEEIIEALSNMNGIISLA-PGR-LGPAIAAemiesgDLLRLSETvirpfyRQKVQLAI 318

                        170       180
                 ....*....|....*....|....*..
gi 495220400 253 ERLARLLEQFGF---KPQGgcALFQWL 276
Cdd:PRK09440 319 ALLRRYLPDEPClihKPEG--AIFLWL 343
PRK07324 PRK07324
transaminase; Validated
 132-214 1.80e-04

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 43.00  E-value: 1.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 132 NPNNPTGlSLTPSRLLDWHTRLA-SRGGWLVVDE---AFMDNTPQLSVAPFTHQvGlIVLRSFGKFFGLAGVRLGFVLAE 207
Cdd:PRK07324 161 NANNPTG-ALMDRAYLEEIVEIArSVDAYVLSDEvyrPLDEDGSTPSIADLYEK-G-ISTNSMSKTYSLPGIRVGWIAAN 237


                 ....*..
gi 495220400 208 RKLLNLL 214
Cdd:PRK07324 238 EEVIDIL 244
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
1-273 2.11e-04

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 42.49  E-value: 2.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400   1 MLEHGGRLRKaarEYGiAEADWlDLSSGlapwpfpVPDIP--------LRAWARLPETGD-------GLE---QAACDY- 61
Cdd:PRK06836  19 MFEEGARLKA---EYG-ADNVF-DFSLG-------NPSVPppaavkeaLRELAEEEDPGLhgympnaGYPevrEAIAESl 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  62 -------YSAAQVLPVAGSQMAIQLLPR--LRRAGKVGVLSP------CYAEHAeawrrcGYIVREVLEQEVDFFIDsLD 126
Cdd:PRK06836  87 nrrfgtpLTADHIVMTCGAAGALNVALKaiLNPGDEVIVFAPyfveyrFYVDNH------GGKLVVVPTDTDTFQPD-LD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 127 VL----------VVVN-PNNPTGLSLTPSRLldwhTRLAS----------RGGWLVVDE-----AFmDNTPQLSVAPFTH 180
Cdd:PRK06836 160 ALeaaitpktkaVIINsPNNPTGVVYSEETL----KALAAlleekskeygRPIYLISDEpyreiVY-DGAEVPYIFKYYD 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 181 QVglIVLRSFGKFFGLAGVRLGFVLAERKLLNllAEQVGPwAVSGPTRVIG--------Q----ACL---LDTEGHARQR 245
Cdd:PRK06836 235 NS--IVVYSFSKSLSLPGERIGYIAVNPEMED--ADDLVA-ALVFANRILGfvnapalmQrvvaKCLdatVDVSIYKRNR 309

                        330       340       350
                 ....*....|....*....|....*....|.
gi 495220400 246 qrseeasERLARLLEQFGF---KPQGGCALF 273
Cdd:PRK06836 310 -------DLLYDGLTELGFecvKPQGAFYLF 333
PRK06290 PRK06290
LL-diaminopimelate aminotransferase;
114-268 5.01e-04

LL-diaminopimelate aminotransferase;


Pssm-ID: 235772  Cd Length: 410  Bit Score: 41.56  E-value: 5.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 114 LEQEVDFF--IDSL--DV-----LVVVN-PNNPTGLSLTPS---RLLDWhtrlASRGGWLVV-DEAF----MDNTPQ--L 173
Cdd:PRK06290 159 LLEENNFLpdLDSIpkDIkekakLLYLNyPNNPTGAVATKEfyeEVVDF----AKENNIIVVqDAAYaaltFDGKPLsfL 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 174 SVaPFTHQVGlIVLRSFGKFFGLAGVRLGFVLAERKLLNLLAEqVGPWAVSGPTRVIGQA---CLLDTEGHARQRQRSEE 250
Cdd:PRK06290 235 SV-PGAKEVG-VEIHSLSKAYNMTGWRLAFVVGNELIVKAFAT-VKDNNDSGQFIAIQKAgiyALDHPEITEKIREKYSR 311

                        170       180
                 ....*....|....*....|.
gi 495220400 251 ASERLARLLEQFGF---KPQG 268
Cdd:PRK06290 312 RLDKLVKILNEVGFkaeMPGG 332
PRK05764 PRK05764
aspartate aminotransferase; Provisional
 47-210 1.45e-03

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 40.11  E-value: 1.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  47 LPEtgdgLEQAACDY--------YSAAQVLpVA--GSQ---MAIQLLprLRRAGKVGVLSPCYAEHAEAWRRCGYIVREV 113
Cdd:PRK05764  70 IPE----LREAIAAKlkrdngldYDPSQVI-VTtgAKQalyNAFMAL--LDPGDEVIIPAPYWVSYPEMVKLAGGVPVFV 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 114 -LEQEVDFFIDSLD----------VLVVVNPNNPTGLSLTPSRLL---DWhtrLASRGGWLVVDEAF-------MDNTPQ 172
Cdd:PRK05764 143 pTGEENGFKLTVEQleaaitpktkALILNSPSNPTGAVYSPEELEaiaDV---AVEHDIWVLSDEIYeklvydgAEFTSI 219

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 495220400 173 LSVAP-FTHQVglIVLRSFGKFFGLAGVRLGFVLAERKL 210
Cdd:PRK05764 220 ASLSPeLRDRT--ITVNGFSKAYAMTGWRLGYAAGPKEL 256
PRK08636 PRK08636
LL-diaminopimelate aminotransferase;
91-221 2.99e-03

LL-diaminopimelate aminotransferase;


Pssm-ID: 236316  Cd Length: 403  Bit Score: 38.92  E-value: 2.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  91 VLSPCYAEHAEAW-------RRCGYIVREVLE-QEVDFFIDSLDVL---------VVVN-PNNPTGLSLTPS---RLLDw 149
Cdd:PRK08636 124 VPDPAYPIHSQAFilaggnvHKMPLEYNEDFElDEDQFFENLEKALresspkpkyVVVNfPHNPTTATVEKSfyeRLVA- 202

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495220400 150 htrLASRGGWLVV-DEAFMDNTPQLSVAPFTHQV-GL--IVLRSF--GKFFGLAGVRLGFVLAERKLLNLLaEQVGPW 221
Cdd:PRK08636 203 ---LAKKERFYIIsDIAYADITFDGYKTPSILEVeGAkdVAVESYtlSKSYNMAGWRVGFVVGNKKLVGAL-KKIKSW 276
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
 128-205 5.28e-03

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 38.48  E-value: 5.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400  128 LVVVNPNNPTGLSLTPSRLLDWhTRLASRGGWLVV-DE-----AFMDNtPQLSVAPFTHQVGLIVLRSFGKFFGLAGVRL 201
Cdd:TIGR01265 173 IVVINPSNPCGSVFSRDHLQKI-AEVAEKLGIPIIaDEiyghmVFGDA-PFIPMASFASIVPVLSLGGISKRWVVPGWRL 250


                  ....
gi 495220400  202 GFVL 205
Cdd:TIGR01265 251 GWII 254
PRK07682 PRK07682
aminotransferase;
128-214 5.31e-03

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 38.18  E-value: 5.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495220400 128 LVVVNPNNPTGLSLTPSRLLDWhTRLASRGGWLVV-DEAFMDNTPQLSVAPFTHQVGL----IVLRSFGKFFGLAGVRLG 202
Cdd:PRK07682 158 ILLCSPNNPTGAVLNKSELEEI-AVIVEKHDLIVLsDEIYAELTYDEAYTSFASIKGMrertILISGFSKGFAMTGWRLG 236

                         90
                 ....*....|..
gi 495220400 203 FVLAERKLLNLL 214
Cdd:PRK07682 237 FIAAPVYFSEAM 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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