|
Name |
Accession |
Description |
Interval |
E-value |
| murB |
PRK00046 |
UDP-N-acetylmuramate dehydrogenase; |
1-332 |
0e+00 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 234593 [Multi-domain] Cd Length: 334 Bit Score: 574.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 1 MSSPNTSLEAFNTLGLAINAQTLTIAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLEDFSGSVVVNAIKGITI-EEHD 79
Cdd:PRK00046 2 QLQMNHSLKPLNTFGIDARARHLVEAESEEQLLEALADARAAGLPVLVLGGGSNVLFTEDFDGTVLLNRIKGIEVlSEDD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 80 EAWHLHVGAGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALHLPTQKIIRLYREECQF 159
Cdd:PRK00046 82 DAWYLHVGAGENWHDLVLWTLQQGMPGLENLALIPGTVGAAPIQNIGAYGVELKDVCDYVEALDLATGEFVRLSAAECRF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 160 GYRDSVFKHAMKNDYVIVAVGLRMAKQWKPVLTYGDLTKLNPATVCAWDIFNAICHMRQSKLPDPKITGNVGSFFKNPLI 239
Cdd:PRK00046 162 GYRDSIFKHEYPDRYAITAVGFRLPKQWQPVLDYGDLARLDPDTVTAQDVFDAVCAIRRSKLPDPKVLGNAGSFFKNPVV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 240 TAEHATALIKQWPAIPHYPQASGEMKLAAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQ 319
Cdd:PRK00046 242 SAEQFEALLAQYPDIPHYPQADGSVKLAAGWLIDQCGLKGFQIGGAAVHEKQALVLVNYGNATGADVLALARHIQQDVRE 321
|
330
....*....|...
gi 495382281 320 KFDVWLEPEVRFI 332
Cdd:PRK00046 322 KFGVELEPEPRFI 334
|
|
| MurB |
COG0812 |
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ... |
7-332 |
2.21e-123 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440574 [Multi-domain] Cd Length: 279 Bit Score: 355.86 E-value: 2.21e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 7 SLEAFNTLGLAINAQTLTIAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLED-FSGSVVVNA-IKGITIEEHdeaWHL 84
Cdd:COG0812 2 PLAPHTTFRIGGPADLLVEPASEEELAALLRAAREAGLPVLVLGGGSNLLVRDDgFDGLVIRLGrLKGIEVDDG---VLV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 85 HVGAGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALHlPTQKIIRLYREECQFGYRDS 164
Cdd:COG0812 79 TAGAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLD-RTGEVRTLSAEECGFGYRDS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 165 VFKHamkNDYVIVAVGLRmakqwkpvltygdLTKLNPATVcaWDIFNAICHMRQSKlpDPKITGNVGSFFKNPlitaeha 244
Cdd:COG0812 158 IFKR---ERYIILSVTFR-------------LKKGDPAEI--AAVMDAVLAIRRSK--QPLELPSAGSFFKNP------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 245 talikqwpaiPHYPqasgemklaAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVW 324
Cdd:COG0812 211 ----------PGDS---------AGWLIEQAGLKGYRIGGAQVSEKHANFLVNRGGATAADVLALIEEVQARVKEKFGVE 271
|
....*...
gi 495382281 325 LEPEVRFI 332
Cdd:COG0812 272 LEPEVRII 279
|
|
| murB |
TIGR00179 |
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ... |
8-333 |
1.04e-116 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 272945 [Multi-domain] Cd Length: 284 Bit Score: 339.04 E-value: 1.04e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 8 LEAFNTLGLAINAQTLTIAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLEDFSGSVVVNAIKGITIEEhDEAWHLHVG 87
Cdd:TIGR00179 1 LAEFTTYKIGGNARHIVCPESIEQLVNVLDNAKEEDQPLLILGEGSNLLILDDGRGGVIINLGKGIDIED-DEGEYVHVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 88 AGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALhLPTQKIIRLYREECQFGYRDSVFK 167
Cdd:TIGR00179 80 GGENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYATIL-LATGKTEWLTNEQLGFGYRTSIFQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 168 HAMkndyvivaVGLRMAKQWKPVLTYGdlTKLNPATVCAWDIFNAICHMRQSKLPDPkitgNVGSFFKNPLitaehatal 247
Cdd:TIGR00179 159 HKY--------VGLVLKAEFQLTLGFG--TRLDPETITAQQVFNKVCRMRTSHYPDP----NAGSFFKNPS--------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 248 ikqwpaiPHYpqasgemklaAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEP 327
Cdd:TIGR00179 216 -------PNH----------AGRLIEECGLKGYQIGGAAVSKQHANFLVNIDNAKSEDVLDLIEHVKAEVGEKYGILLEP 278
|
....*.
gi 495382281 328 EVRFIG 333
Cdd:TIGR00179 279 EVKIIG 284
|
|
| MurB_C |
pfam02873 |
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ... |
209-332 |
2.00e-42 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 460730 [Multi-domain] Cd Length: 99 Bit Score: 142.49 E-value: 2.00e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 209 IFNAICHMRQSKL-PDPKITGNVGSFFKNPlitaehatalikqwpaIPHYpqasgemklaAGWLIDQCGLKGFRVGGAAV 287
Cdd:pfam02873 1 IRAAMLELRRRRLaKQPLDPPSAGSFFKNP----------------VGHS----------AGWLIEQAGLKGYRIGGAQV 54
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 495382281 288 HRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEPEVRFI 332
Cdd:pfam02873 55 SEKHANFLVNTGGATAADVLALIEEVRERVKEKFGVELEPEVRII 99
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| murB |
PRK00046 |
UDP-N-acetylmuramate dehydrogenase; |
1-332 |
0e+00 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 234593 [Multi-domain] Cd Length: 334 Bit Score: 574.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 1 MSSPNTSLEAFNTLGLAINAQTLTIAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLEDFSGSVVVNAIKGITI-EEHD 79
Cdd:PRK00046 2 QLQMNHSLKPLNTFGIDARARHLVEAESEEQLLEALADARAAGLPVLVLGGGSNVLFTEDFDGTVLLNRIKGIEVlSEDD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 80 EAWHLHVGAGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALHLPTQKIIRLYREECQF 159
Cdd:PRK00046 82 DAWYLHVGAGENWHDLVLWTLQQGMPGLENLALIPGTVGAAPIQNIGAYGVELKDVCDYVEALDLATGEFVRLSAAECRF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 160 GYRDSVFKHAMKNDYVIVAVGLRMAKQWKPVLTYGDLTKLNPATVCAWDIFNAICHMRQSKLPDPKITGNVGSFFKNPLI 239
Cdd:PRK00046 162 GYRDSIFKHEYPDRYAITAVGFRLPKQWQPVLDYGDLARLDPDTVTAQDVFDAVCAIRRSKLPDPKVLGNAGSFFKNPVV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 240 TAEHATALIKQWPAIPHYPQASGEMKLAAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQ 319
Cdd:PRK00046 242 SAEQFEALLAQYPDIPHYPQADGSVKLAAGWLIDQCGLKGFQIGGAAVHEKQALVLVNYGNATGADVLALARHIQQDVRE 321
|
330
....*....|...
gi 495382281 320 KFDVWLEPEVRFI 332
Cdd:PRK00046 322 KFGVELEPEPRFI 334
|
|
| MurB |
COG0812 |
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ... |
7-332 |
2.21e-123 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440574 [Multi-domain] Cd Length: 279 Bit Score: 355.86 E-value: 2.21e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 7 SLEAFNTLGLAINAQTLTIAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLED-FSGSVVVNA-IKGITIEEHdeaWHL 84
Cdd:COG0812 2 PLAPHTTFRIGGPADLLVEPASEEELAALLRAAREAGLPVLVLGGGSNLLVRDDgFDGLVIRLGrLKGIEVDDG---VLV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 85 HVGAGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALHlPTQKIIRLYREECQFGYRDS 164
Cdd:COG0812 79 TAGAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLD-RTGEVRTLSAEECGFGYRDS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 165 VFKHamkNDYVIVAVGLRmakqwkpvltygdLTKLNPATVcaWDIFNAICHMRQSKlpDPKITGNVGSFFKNPlitaeha 244
Cdd:COG0812 158 IFKR---ERYIILSVTFR-------------LKKGDPAEI--AAVMDAVLAIRRSK--QPLELPSAGSFFKNP------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 245 talikqwpaiPHYPqasgemklaAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVW 324
Cdd:COG0812 211 ----------PGDS---------AGWLIEQAGLKGYRIGGAQVSEKHANFLVNRGGATAADVLALIEEVQARVKEKFGVE 271
|
....*...
gi 495382281 325 LEPEVRFI 332
Cdd:COG0812 272 LEPEVRII 279
|
|
| murB |
TIGR00179 |
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ... |
8-333 |
1.04e-116 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 272945 [Multi-domain] Cd Length: 284 Bit Score: 339.04 E-value: 1.04e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 8 LEAFNTLGLAINAQTLTIAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLEDFSGSVVVNAIKGITIEEhDEAWHLHVG 87
Cdd:TIGR00179 1 LAEFTTYKIGGNARHIVCPESIEQLVNVLDNAKEEDQPLLILGEGSNLLILDDGRGGVIINLGKGIDIED-DEGEYVHVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 88 AGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALhLPTQKIIRLYREECQFGYRDSVFK 167
Cdd:TIGR00179 80 GGENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYATIL-LATGKTEWLTNEQLGFGYRTSIFQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 168 HAMkndyvivaVGLRMAKQWKPVLTYGdlTKLNPATVCAWDIFNAICHMRQSKLPDPkitgNVGSFFKNPLitaehatal 247
Cdd:TIGR00179 159 HKY--------VGLVLKAEFQLTLGFG--TRLDPETITAQQVFNKVCRMRTSHYPDP----NAGSFFKNPS--------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 248 ikqwpaiPHYpqasgemklaAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEP 327
Cdd:TIGR00179 216 -------PNH----------AGRLIEECGLKGYQIGGAAVSKQHANFLVNIDNAKSEDVLDLIEHVKAEVGEKYGILLEP 278
|
....*.
gi 495382281 328 EVRFIG 333
Cdd:TIGR00179 279 EVKIIG 284
|
|
| murB |
PRK13903 |
UDP-N-acetylmuramate dehydrogenase; |
5-333 |
4.76e-64 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237552 [Multi-domain] Cd Length: 363 Bit Score: 207.12 E-value: 4.76e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 5 NTSLEAFNTLGLAINAQTLTIAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLED-FSGSVVVNAIKGITIEEHDEAwh 83
Cdd:PRK13903 18 DVPLAPLTTLRVGGPARRLVTCTSTEELVAAVRELDAAGEPLLVLGGGSNLVIADDgFDGTVVRVATRGVTVDCGGGL-- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 84 LHVGAGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALHLPTQKIIRLYREECQFGYRD 163
Cdd:PRK13903 96 VRAEAGAVWDDVVARTVEAGLGGLECLSGIPGSAGATPVQNVGAYGQEVSDTITRVRLLDRRTGEVRWVPAADLGFGYRT 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 164 SVFKHAMKndYVIVAV--GLRMAKQWKPVlTYGDLT---------KLNPATVCAwdifnAICHMRQSK---L-PDPKITG 228
Cdd:PRK13903 176 SVLKHSDR--AVVLEVefQLDPSGLSAPL-RYGELAralgvepgeRVPPAAVRE-----AVLALRAGKgmvLdPADHDTW 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 229 NVGSFFKNPLITAE-----HATALIKQWPAIPHYPQASGEMKLAAGWLIDQCGL-KGFRVGG--AAVHRQQALVLINENH 300
Cdd:PRK13903 248 SAGSFFTNPVVSPAvaerlAARVAERLGDPVPRYPAGDGGVKLSAAWLIERAGFgKGYPGGGapARLSTKHTLALTNRGG 327
|
330 340 350
....*....|....*....|....*....|...
gi 495382281 301 ATPQDIVDLAHLVRDRVGQKFDVWLEPEVRFIG 333
Cdd:PRK13903 328 ATTADLVALAREVRDGVRDAFGVTLVPEPVLVG 360
|
|
| murB |
PRK13905 |
UDP-N-acetylmuramate dehydrogenase; |
20-333 |
2.21e-52 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237553 [Multi-domain] Cd Length: 298 Bit Score: 174.91 E-value: 2.21e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 20 AQTLTIAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLED-FSGSVVVNA--IKGITIEEHdeawHLHVGAGENWHALV 96
Cdd:PRK13905 31 ADYLVEPADIEDLQEFLKLLKENNIPVTVLGNGSNLLVRDGgIRGVVIRLGkgLNEIEVEGN----RITAGAGAPLIKLA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 97 EQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALhLPTQKIIRLYREECQFGYRDSVFKhamKNDYVI 176
Cdd:PRK13905 107 RFAAEAGLSGLEFAAGIPGTVGGAVFMNAGAYGGETADVLESVEVL-DRDGEIKTLSNEELGFGYRHSALQ---EEGLIV 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 177 VAVGLRmakqwkpvLTYGDLTKLNPATvcawdifNAICHMRQSKLP--DPkitgNVGSFFKNPLitaehatalikqwpai 254
Cdd:PRK13905 183 LSATFQ--------LEPGDKEEIKARM-------DELLARREATQPleYP----SAGSVFKNPP---------------- 227
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495382281 255 PHYpqasgemklaAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEPEVRFIG 333
Cdd:PRK13905 228 GHF----------AGKLIEEAGLKGYRIGGAQVSEKHANFIINTGGATAADIEDLIEHVQKTVKEKFGVELEWEVRIIG 296
|
|
| MurB_C |
pfam02873 |
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ... |
209-332 |
2.00e-42 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 460730 [Multi-domain] Cd Length: 99 Bit Score: 142.49 E-value: 2.00e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 209 IFNAICHMRQSKL-PDPKITGNVGSFFKNPlitaehatalikqwpaIPHYpqasgemklaAGWLIDQCGLKGFRVGGAAV 287
Cdd:pfam02873 1 IRAAMLELRRRRLaKQPLDPPSAGSFFKNP----------------VGHS----------AGWLIEQAGLKGYRIGGAQV 54
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 495382281 288 HRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEPEVRFI 332
Cdd:pfam02873 55 SEKHANFLVNTGGATAADVLALIEEVRERVKEKFGVELEPEVRII 99
|
|
| PRK14653 |
PRK14653 |
UDP-N-acetylmuramate dehydrogenase; |
46-329 |
8.17e-31 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237778 [Multi-domain] Cd Length: 297 Bit Score: 118.40 E-value: 8.17e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 46 FIVLGEGSNVLFLEDFSGSVVV--NAIKGITIEEHDeawhLHVGAGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQ 123
Cdd:PRK14653 59 VKILGNGTNVLPKDEPMDFVVVstERLDDIFVDNDK----IICESGLSLKKLCLVAAKNGLSGFENAYGIPGSVGGAVYM 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 124 NIGAYGVEFKDICHYVEALHlpTQKIIRLYREECQFGYRDSVFKHamKNDYVIVAVGLRMAKqwkpvltyGDltklnpat 203
Cdd:PRK14653 135 NAGAYGWETAENIVEVVAYD--GKKIIRLGKNEIKFSYRNSIFKE--EKDLIILRVTFKLKK--------GN-------- 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 204 vcAWDIFNaicHMRQSKL----PDPKITGNVGSFFKNPlitaehatalikqwpaiphypqasgEMKLAAGWLIDQCGLKG 279
Cdd:PRK14653 195 --KNEIYN---LMLETMKkrveKQPLEFPSAGSVFKRP-------------------------RKDFYVGSAIEKLGLKG 244
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 495382281 280 FRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEPEV 329
Cdd:PRK14653 245 FSIGGAQISEKHAGFIINYNNAKAEDVLKLIEYVKDKIYENYNVELETEI 294
|
|
| PRK14649 |
PRK14649 |
UDP-N-acetylmuramate dehydrogenase; |
20-333 |
5.54e-30 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173112 [Multi-domain] Cd Length: 295 Bit Score: 116.09 E-value: 5.54e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 20 AQTLTIAETPD--AITLAWKNSQQLnqPFIVLGEGSNVLFL-EDFSGSVVVNAIKGITIEEHDEAWHLHVGAGENWHALV 96
Cdd:PRK14649 21 ARYFVEPTTPDeaIAAAAWAEQRQL--PLFWLGGGSNLLVRdEGFDGLVARYRGQRWELHEHGDTAEVWVEAGAPMAGTA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 97 EQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALhLPTQKIIRLYREECQFGYRDSVFKHaMKNDYVI 176
Cdd:PRK14649 99 RRLAAQGWAGLEWAEGLPGTIGGAIYGNAGCYGGDTATVLIRAWLL-LNGSECVEWSVHDFAYGYRTSVLKQ-LRADGIT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 177 VAVGLRMAKQWKpvLTYGDLTKLNPAtvcawdiFNAICHMRQSKLPdpkITGNVGSFFKNPlitaehatalikqwpaiph 256
Cdd:PRK14649 177 WRPPLVLAARFR--LHRDDPTALAAR-------MEAIAAERKQKTP---AGSSCGSVFKNP------------------- 225
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495382281 257 ypqaSGEmklAAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEPEVRFIG 333
Cdd:PRK14649 226 ----PGD---SAGRLIEAAGLKGTRIGDAEIATRHANYIINLGGARAADILRLIDLARTRVLAQFGIELELEVRIIG 295
|
|
| PRK12436 |
PRK12436 |
UDP-N-acetylmuramate dehydrogenase; |
30-333 |
3.76e-22 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 171497 [Multi-domain] Cd Length: 305 Bit Score: 94.69 E-value: 3.76e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 30 DAITLAWKNSQQLNQPFIVLGEGSNVLFLEDFSGSVVVNA--IKGITIEehdeAWHLHVGAGENWHALVEQTLKKGITGL 107
Cdd:PRK12436 47 DEIQEVIKYANKYNIPVTFLGNGSNVIIKDGGIRGITVSLihITGVTVT----GTTIVAQCGAAIIDVSRIALDHNLTGL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 108 ENLALIPGMAGSAPIQNIGAYGVEFKDIchYVEALHLPTQ-KIIRLYREECQFGYRDSVFKHamkNDYVIVAVGLRMAKQ 186
Cdd:PRK12436 123 EFACGIPGSVGGALYMNAGAYGGEISFV--LTEAVVMTGDgELRTLTKEAFEFGYRKSVFAN---NHYIILEARFELEEG 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 187 wkpvlTYGDL-TKLNPATvcawdifnaicHMRQSKlpDPKITGNVGSFFKNPlitaehatalikqwpaiPHYpqasgemk 265
Cdd:PRK12436 198 -----VYEEIkAKMDDLT-----------FKRESK--QPLEYPSCGSVFKRP-----------------PNN-------- 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495382281 266 lAAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEPEVRFIG 333
Cdd:PRK12436 235 -FAGKLIQESGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIG 301
|
|
| FAD_binding_4 |
pfam01565 |
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most ... |
25-152 |
8.46e-21 |
|
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 426326 [Multi-domain] Cd Length: 139 Bit Score: 86.87 E-value: 8.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 25 IAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLEDFSGSVVVN--AIKGItIEEHDEAWHLHVGAGENWHALVEQTLKK 102
Cdd:pfam01565 6 LPESEEEVAAIVRLANENGLPVLPRGGGSSLLGGAVQTGGIVLDlsRLNGI-LEIDPEDGTATVEAGVTLGDLVRALAAK 84
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 495382281 103 G-ITGLENLALIPGMAGSAPIQNIGAYGVEF----KDICHYVEALhLPTQKIIRL 152
Cdd:pfam01565 85 GlLLGLDPGSGIPGTVGGAIATNAGGYGSEKygltRDNVLGLEVV-LADGEVVRL 138
|
|
| PRK14651 |
PRK14651 |
UDP-N-acetylmuramate dehydrogenase; |
8-326 |
2.23e-20 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237776 [Multi-domain] Cd Length: 273 Bit Score: 89.11 E-value: 2.23e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 8 LEAFNTLGLAINAQTLTIaETPDAITLAwknsqqLNQPFIVLGEGSNVLFLEDFSGSVVVNaIKGITIEEHDEAWhlhVG 87
Cdd:PRK14651 9 LARYTTLGVGGPAELWTV-ETHEQLAEA------TEAPYRVLGGGSNLLVSDAGVPERVIR-LGGEFAEWDLDGW---VG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 88 AGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEALHlpTQKIIRLYREECQFGYRDSvfk 167
Cdd:PRK14651 78 GGVPLPGLVRRAARLGLSGLEGLVGIPAQVGGAVKMNAGTRFGEMADALHTVEIVH--DGGFHQYSPDELGFGYRHS--- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 168 hAMKNDYVIVAVGLRmakqwkpvltygdLTKLNPATVCAwdifnAICHMRQSKLPDPKITgNVGSFFKNPlitaehatal 247
Cdd:PRK14651 153 -GLPPGHVVTRVRLK-------------LRPSTPEAVLA-----KMALVDAARKGQPKKK-SAGCAFKNP---------- 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 248 ikqwpaiphyPQASgemklaAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVG----QKFDV 323
Cdd:PRK14651 203 ----------PGDS------AGRLIDEAGLKGTRVGDAMISPEHGNFIVNLGGATAADVHALLRRVRARVGlpleLEWEL 266
|
...
gi 495382281 324 WLE 326
Cdd:PRK14651 267 WPE 269
|
|
| murB |
PRK13906 |
UDP-N-acetylmuramate dehydrogenase; |
39-333 |
8.53e-20 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 184386 [Multi-domain] Cd Length: 307 Bit Score: 88.34 E-value: 8.53e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 39 SQQLNQPFIVLGEGSNVLFLEDFSGSVVVNAIKGITIEEHDEAwhLHVGAGENWHALVEQTLKKGITGLENLALIPGMAG 118
Cdd:PRK13906 56 AYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDA--IIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIG 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 119 SAPIQNIGAYGVEFKDICHYveALHLPTQ-KIIRLYREECQFGYRDSVFKhamKNDYVIVAVGLRMAKqwkpvltyGDLT 197
Cdd:PRK13906 134 GAVYMNAGAYGGEVKDCIDY--ALCVNEQgSLIKLTTKELELDYRNSIIQ---KEHLVVLEAAFTLAP--------GKMT 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 198 KLNPAtvcawdiFNAICHMRQSKlpDPKITGNVGSFFKNPlitaehatalikqwPAipHYpqasgemklaAGWLIDQCGL 277
Cdd:PRK13906 201 EIQAK-------MDDLTERRESK--QPLEYPSCGSVFQRP--------------PG--HF----------AGKLIQDSNL 245
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 495382281 278 KGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEPEVRFIG 333
Cdd:PRK13906 246 QGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIG 301
|
|
| murB |
PRK13904 |
UDP-N-acetylmuramate dehydrogenase; |
83-329 |
1.87e-17 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 184384 [Multi-domain] Cd Length: 257 Bit Score: 80.74 E-value: 1.87e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 83 HLHVGAGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDICHYVEalhlpTQKIIRLyREECQFGYR 162
Cdd:PRK13904 68 CLEIGGATKSGKIFNYAKKNNLGGFEFLGKLPGTLGGLVKMNAGLKEYEISNNLESIC-----TNGGWIE-KEDIGFGYR 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 163 DSVFKHamkndyVIVAVGLRmakqwkpvLTYGDLTKLNpatvcawDIFNAichMRQSKlpdPKiTGNVGSFFKNPlitae 242
Cdd:PRK13904 142 SSGING------VILEARFK--------KTHGFDEELL-------EAFKS---MRKNQ---PK-GPSFGSCFKNP----- 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 243 hatalikqwpaIPHYpqasgemklaAGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFD 322
Cdd:PRK13904 189 -----------KGDY----------AGRLIEAVGLKGYCKGGAGFSEEHANFLVNLGGATFEDALDLIELAKKRVLEEFG 247
|
....*..
gi 495382281 323 VWLEPEV 329
Cdd:PRK13904 248 INLEEEV 254
|
|
| PRK14652 |
PRK14652 |
UDP-N-acetylmuramate dehydrogenase; |
20-333 |
1.99e-17 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237777 [Multi-domain] Cd Length: 302 Bit Score: 81.46 E-value: 1.99e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 20 AQTLTIAETPDAITLAWKNSQQLNQPFIVLGEGSNVLFLEDFSGSVVVNAIKGITIEEHDEAwHLHVGAGENWHALVEQT 99
Cdd:PRK14652 36 ADLLVRPADPDALSALLRAVRELGVPLSILGGGANTLVADAGVRGVVLRLPQDFPGESTDGG-RLVLGAGAPISRLPARA 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 100 LKKGITGLENLALIPGMAGSAPIQNIGAYGVEFKDIchyVEALHLPTQKIIR-LYREECQFGYRDSvfkhAMKNDYVIVA 178
Cdd:PRK14652 115 HAHGLVGMEFLAGIPGTLGGAVAMNAGTKLGEMKDV---VTAVELATADGAGfVPAAALGYAYRTC----RLPPGAVITR 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 179 VGLRMAKqwkpvltyGDLtklnpatVCAWDIFNAICHMRQSKLPDPKitGNVGSFFKNPliTAEHAtalikqwpaiphyp 258
Cdd:PRK14652 188 VEVRLRP--------GDV-------AASEALMRADRERRRRTQPLDR--PTFGSTFTNP--PGDYA-------------- 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495382281 259 qasgemklaaGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEPEVRFIG 333
Cdd:PRK14652 235 ----------GRLVEAVGLKGHRVGGAIWSPVHANFVTNLGGATARDVLALVRLARARVKERFGIALETEVRLLG 299
|
|
| PRK14648 |
PRK14648 |
UDP-N-acetylmuramate dehydrogenase; |
37-333 |
3.99e-10 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173111 [Multi-domain] Cd Length: 354 Bit Score: 60.51 E-value: 3.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 37 KNSQQLNQPFIVLGEGSNVLFLEDFSGSVVVNAIKGITIE---EHDEAWHLHVGAGENWHALVEQTLKKGITGLENLALI 113
Cdd:PRK14648 47 EEAQRARIPLSLIGGGSNVLIADEGVPGLMLSLRRFRSLHtqtQRDGSVLVHAGAGLPVAALLAFCAHHALRGLETFAGL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 114 PGMAGSAPIQNIGAYGVEFKDICHYVEAL----------HLP-TQKIIRLYREEC---------------------QFGY 161
Cdd:PRK14648 127 PGSVGGAAYMNARCYGRAIADCFHSARTLvlhpvrsrakELPeVRKNAQDKRGEClgldggpftcssfqtvfaragDWGY 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 162 RDSVFKHAMKndyVIVAVGLRMAKQWKPVLTYGdltklNPATVCAwdifnaicHMrQSKLPDPKITG-----NVGSFFKN 236
Cdd:PRK14648 207 KRSPFQSPHG---VELHAGRRLILSLCVRLTPG-----NPAQIRK--------HM-QEKIADRISKGqfrfpSAGSAFKN 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 237 PlitaehatalikqwpaiPHYPQASgemklaaGWLIDQCGLKGFRVGGAAVHRQQALVLINENHATPQDIVDLAHLVRDR 316
Cdd:PRK14648 270 N-----------------PAFGKPS-------GILIEEAGLRGTSCGAAQVAPWHGNLIINTGNATAHQVRTLLRVVRQR 325
|
330
....*....|....*..
gi 495382281 317 VGQKFDVWLEPEVRFIG 333
Cdd:PRK14648 326 VFETHGVWLEREIIFSG 342
|
|
| PRK14650 |
PRK14650 |
UDP-N-acetylmuramate dehydrogenase; |
48-333 |
6.17e-10 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173113 [Multi-domain] Cd Length: 302 Bit Score: 59.47 E-value: 6.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 48 VLGEGSNVLFLEDFSGSVVVNAIKGIT-IEEHDEawHLHVGAGENWHALVEQTLKKGITGLENLALIPGMAGSAPIQNIG 126
Cdd:PRK14650 61 ILGGGSNILINDEEEIDFPIIYTGHLNkIEIHDN--QIVAECGTNFEDLCKFALQNELSGLEFIYGLPGTLGGAIWMNAR 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 127 AYGVEFKDICHYVEALHLPTQKIIRLYREEcQFGYRDSVFKHamKNdYVIVAVGLRMAKQWKPVLTygdltklnpatvca 206
Cdd:PRK14650 139 CFGNEISEILDKITFIDEKGKTICKKFKKE-EFKYKISPFQN--KN-TFILKATLNLKKGNKKHIE-------------- 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495382281 207 wDIFNAICHMRQSKlpDPKITGNVGSFFKNplitaehATALIKqwpaiphypqasgemklAAGWLIDQCGLKGFRVGGAA 286
Cdd:PRK14650 201 -EIMKQNKQIRINK--GHYLFPSSGSTFKN-------NKAFLK-----------------PTGQIIEECKLKGLSIGGAT 253
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 495382281 287 VHRQQALVLINENHATPQDIVDLAHLVRDRVGQKFDVWLEPEVRFIG 333
Cdd:PRK14650 254 VSHYHGNFIININNATSKDIKTLIEKVKTEVQIKTGFLLEEEVLYIG 300
|
|
| |
