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Conserved domains on  [gi|495639927|ref|WP_008364506|]
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folate family ECF transporter S component [Mycoplasma feriruminatoris]

Protein Classification

ECF transporter S component family protein( domain architecture ID 229498)

ECF transporter S component family protein is an integral membrane subunit that captures the substrate of an energy coupling factor (ECF) transporter

Gene Ontology:  GO:0035796|GO:0022857
PubMed:  30485755|22574898

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ECF_trnsprt super family cl21488
ECF transporter, substrate-specific component; Energy-coupling factor (ECF) transporters ...
 39-198 3.25e-09

ECF transporter, substrate-specific component; Energy-coupling factor (ECF) transporters consist of a substrate-specific component (known as the S component), and an energy-coupling module. The substrate-binding component is a small integral membrane protein which captures specific substrates and forms an active transporter in the presence of the energy-coupling AT module.


The actual alignment was detected with superfamily member TIGR04518:

Pssm-ID: 473881 [Multi-domain]  Cd Length: 162  Bit Score: 54.50  E-value: 3.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495639927   39 MMAMQVALIVLLTNVIGYSGVFgARLMFGNFILFLSGMLFGPMGGALVGAISYTAG-LVMPNIFIHFSFMAVYMLYAMLG 117
Cdd:TIGR04518   9 ILALLVALSIILSRFLSIQTGN-LRISFGFLPVILAGMLFGPVAGAIVGAVADLLGcMLFGYGTFFPGFTLSAALTGLIY 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495639927  118 SLVFIKKQKSRvtYTISVVVLLFIASFTLTFISHPIAVLSIGKSPYVyatlikklIVFPIDAAIEPILIISTFEVSVLIL 197
Cdd:TIGR04518  88 GLFFYKKKNKK--LFLRLAAAVVIVQIIISLVLTSIWLSILYGSPLT--------ALLPIRLIKAIIMIPVEIVVIYLLL 157


                  .
gi 495639927  198 K 198
Cdd:TIGR04518 158 K 158
 
Name Accession Description Interval E-value
ECF_S_folT_fam TIGR04518
ECF transporter S component, folate family; Members of this model are the multiple ...
 39-198 3.25e-09

ECF transporter S component, folate family; Members of this model are the multiple membrane-spanning S (specificity) component of ECF (energy coupling factor) type uptake transporters. All seed members were found in the vicinity of the bifunctional enzyme folC, involved in making active cofactor from imported folate. However, some species have multiple members of this family, suggesting some diversity of function. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275311 [Multi-domain]  Cd Length: 162  Bit Score: 54.50  E-value: 3.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495639927   39 MMAMQVALIVLLTNVIGYSGVFgARLMFGNFILFLSGMLFGPMGGALVGAISYTAG-LVMPNIFIHFSFMAVYMLYAMLG 117
Cdd:TIGR04518   9 ILALLVALSIILSRFLSIQTGN-LRISFGFLPVILAGMLFGPVAGAIVGAVADLLGcMLFGYGTFFPGFTLSAALTGLIY 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495639927  118 SLVFIKKQKSRvtYTISVVVLLFIASFTLTFISHPIAVLSIGKSPYVyatlikklIVFPIDAAIEPILIISTFEVSVLIL 197
Cdd:TIGR04518  88 GLFFYKKKNKK--LFLRLAAAVVIVQIIISLVLTSIWLSILYGSPLT--------ALLPIRLIKAIIMIPVEIVVIYLLL 157


                  .
gi 495639927  198 K 198
Cdd:TIGR04518 158 K 158
ECF-S COG4720
ECF-type riboflavin transporter, membrane (S) component [Coenzyme transport and metabolism];
39-90 9.57e-03

ECF-type riboflavin transporter, membrane (S) component [Coenzyme transport and metabolism];


Pssm-ID: 443755 [Multi-domain]  Cd Length: 170  Bit Score: 35.98  E-value: 9.57e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 495639927  39 MMAMQVALIVLLTNVIG-YSGVFGARLMFGNFILFLSGMLFGPMGGALVGAIS 90
Cdd:COG4720   10 LIALFAALVFVLTMFIKiPIPITNGYIHLGDAFIYLAALLFGPKAGALAGGIG 62
 
Name Accession Description Interval E-value
ECF_S_folT_fam TIGR04518
ECF transporter S component, folate family; Members of this model are the multiple ...
 39-198 3.25e-09

ECF transporter S component, folate family; Members of this model are the multiple membrane-spanning S (specificity) component of ECF (energy coupling factor) type uptake transporters. All seed members were found in the vicinity of the bifunctional enzyme folC, involved in making active cofactor from imported folate. However, some species have multiple members of this family, suggesting some diversity of function. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275311 [Multi-domain]  Cd Length: 162  Bit Score: 54.50  E-value: 3.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495639927   39 MMAMQVALIVLLTNVIGYSGVFgARLMFGNFILFLSGMLFGPMGGALVGAISYTAG-LVMPNIFIHFSFMAVYMLYAMLG 117
Cdd:TIGR04518   9 ILALLVALSIILSRFLSIQTGN-LRISFGFLPVILAGMLFGPVAGAIVGAVADLLGcMLFGYGTFFPGFTLSAALTGLIY 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495639927  118 SLVFIKKQKSRvtYTISVVVLLFIASFTLTFISHPIAVLSIGKSPYVyatlikklIVFPIDAAIEPILIISTFEVSVLIL 197
Cdd:TIGR04518  88 GLFFYKKKNKK--LFLRLAAAVVIVQIIISLVLTSIWLSILYGSPLT--------ALLPIRLIKAIIMIPVEIVVIYLLL 157


                  .
gi 495639927  198 K 198
Cdd:TIGR04518 158 K 158
ECF-S COG4720
ECF-type riboflavin transporter, membrane (S) component [Coenzyme transport and metabolism];
39-90 9.57e-03

ECF-type riboflavin transporter, membrane (S) component [Coenzyme transport and metabolism];


Pssm-ID: 443755 [Multi-domain]  Cd Length: 170  Bit Score: 35.98  E-value: 9.57e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 495639927  39 MMAMQVALIVLLTNVIG-YSGVFGARLMFGNFILFLSGMLFGPMGGALVGAIS 90
Cdd:COG4720   10 LIALFAALVFVLTMFIKiPIPITNGYIHLGDAFIYLAALLFGPKAGALAGGIG 62
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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