|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
1-341 |
0e+00 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 584.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 1 MEKKQIDWSSIGFGYIPTEKRYVSNYKDGKWDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNA 80
Cdd:PRK13357 12 DEKRAIDWANLGFGYVFTDHMVVIDYKDGKWHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLFRPDANA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 81 KRFADSARRLEMPVFPEDRFVDAIVQVVKANAAYVPPYGSGASLYIRPYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKG 160
Cdd:PRK13357 92 KRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVPPYGEGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPVGAYFKG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 161 GAKPITIKVS-DFDRAAPHGTGHIKAGLNYAMSLHAIVTAHEEGYAENMYLDAATRTKVEETGGANFIFVTKDGKVVTPK 239
Cdd:PRK13357 172 GVKPVSIWVSdEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTYIEEVGGMNFFFITKDGTVTPPL 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 240 SNSILPSITRRSILYVAEHyLGLETEEREVYLDEVKD------FAECGLCGTAAVISPVGKIVDHGKEICFPSGmdEMGP 313
Cdd:PRK13357 252 SGSILPGITRDSLLQLAED-LGLTVEERPVSIDEWQAdaasgeFTEAFACGTAAVITPIGGIKYKDKEFVIGDG--EVGP 328
|
330 340
....*....|....*....|....*...
gi 495645031 314 VIKKLYETLTGIQMGHIEAPEGWIQVVE 341
Cdd:PRK13357 329 VTQKLYDELTGIQFGDVEDPHGWIVKVD 356
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
31-337 |
4.24e-140 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 399.52 E-value: 4.24e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 31 WDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNAKRFADSARRLEMPVFPEDRFVDAIVQVVKA 110
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 111 NAAYVPPYGSGASLYIRPYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKGGAKPITIKVS-DFDRAAPHGTGHIKAGLNY 189
Cdd:TIGR01123 81 NKDWVPPYGSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKGGLAPVSIFVTtEYDRAAPGGTGAVKVGGNY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 190 AMSLHAIVTAHEEGYAENMYLDAATRTKVEETGGANFIFVTKDG-KVVTPKSNSILPSITRRSILYVAEHyLGLETEERE 268
Cdd:TIGR01123 161 AASLLAQAKAAEQGCDQVVYLDPVEHTYIEEVGAMNFFFITGDGeLVTPPLSGSILPGITRDSLLQLAKD-LGMEVEERR 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495645031 269 VYLDEVKDFAECG----LCGTAAVISPVGKIVDHGKEICFPSGmdEMGPVIKKLYETLTGIQMGHIEAPEGWI 337
Cdd:TIGR01123 240 IDIDELKAFVEAGeivfACGTAAVITPVGEIQHGGKEVVFASG--QPGEVTKALYDELTDIQYGDFEDPYGWI 310
|
|
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
48-328 |
2.56e-126 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 363.05 E-value: 2.56e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 48 AGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNAKRFADSARRLEMPVFPEDRFVDAIVQVVKANAAYvPPYGSGASLYIR 127
Cdd:cd01557 6 THALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADW-VPYGGGASLYIR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 128 PYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKGGAKPITIKVSDFDRAAPHGTGHIKAGLNYAMSLHAIVTAHEEGYAEN 207
Cdd:cd01557 85 PFIFGTDPQLGVSPALEYLFAVFASPVGAYFKGGEKGVSALVSSFRRAAPGGPGAAKAGGNYAASLLAQKEAAEKGYDQA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 208 MYLDAAtRTKVEETGGANFIFVtKDGKVVTPKSN-SILPSITRRSILYVAEHyLGLETEEREVYLDEVKDFAECGLCGTA 286
Cdd:cd01557 165 LWLDGA-HGYVAEVGTMNIFFV-KDGELITPPLDgSILPGITRDSILELARD-LGIKVEERPITRDELYEADEVFATGTA 241
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 495645031 287 AVISPVGKIVDHGKEICFPSGmdemGPVIKKLYETLTGIQMG 328
Cdd:cd01557 242 AVVTPVGEIDYRGKEPGEGEV----GPVTKKLYDLLTDIQYG 279
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
31-332 |
2.68e-87 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 263.97 E-value: 2.68e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 31 WDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYtteDGRIvvFRPDMNAKRFADSARRLEMPV-FPEDRFVDAIVQVVK 109
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAY---DGRL--FRLDEHLARLNRSAKRLGIPIpYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 110 ANAayvppygsGASLYIRPYMFGSNPVIGVKPAD-EYQFRAFVTPVGPYFKGG-AKPITIKVSDFDRAAPHGTGHIKAGl 187
Cdd:COG0115 79 ANG--------LEDGYIRPQVTRGVGGRGVFAEEyEPTVIIIASPLPAYPAEAyEKGVRVITSPYRRAAPGGLGGIKTG- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 188 NYAMSLHAIVTAHEEGYAENMYLDaaTRTKVEETGGANFIFVtKDGKVVTPK-SNSILPSITRRSILYVAEHyLGLETEE 266
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLLD--TDGYVAEGSGSNVFIV-KDGVLVTPPlSGGILPGITRDSVIELARE-LGIPVEE 225
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 495645031 267 REVYLDEVKDFAECGLCGTAAVISPVGKIVDHgkeiCFPSGmdEMGPVIKKLYETLTGIQMGHIEA 332
Cdd:COG0115 226 RPISLEELYTADEVFLTGTAAEVTPVTEIDGR----PIGDG--KPGPVTRRLRELYTDIVRGEAED 285
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
56-295 |
1.48e-34 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 125.93 E-value: 1.48e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 56 SVFEGMKAYtteDGRIvvFRPDMNAKRFADSARRLEMPV-FPEDRFVDAIVQVVKANAAYVPpygsgaslYIRPYMFGSN 134
Cdd:pfam01063 1 GVFETLRVY---NGKI--FFLDEHLARLRRSAKLLGIPLpFDEEDLRKIIEELLKANGLGVG--------RLRLTVSRGP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 135 PVIGvKPADEYQFRAFVTPVGPYFKGGAKPITIKVSDFDRAAPHGTghIKaGLNYAMSLHAIVTAHEEGYAENMYLDAAT 214
Cdd:pfam01063 68 GGFG-LPTSDPTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLPG--AK-TLNYLENVLARREAKAQGADDALLLDEDG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 215 RtkVEETGGANfIFVTKDGKVVTPK-SNSILPSITRRSILYVAEHyLGLETEEREVYLDEVKDFAECGLCGTAAVISPVG 293
Cdd:pfam01063 144 N--VTEGSTSN-VFLVKGGTLYTPPlESGILPGITRQALLDLAKA-LGLEVEERPITLADLQEADEAFLTNSLRGVTPVS 219
|
..
gi 495645031 294 KI 295
Cdd:pfam01063 220 SI 221
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
1-341 |
0e+00 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 584.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 1 MEKKQIDWSSIGFGYIPTEKRYVSNYKDGKWDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNA 80
Cdd:PRK13357 12 DEKRAIDWANLGFGYVFTDHMVVIDYKDGKWHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLFRPDANA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 81 KRFADSARRLEMPVFPEDRFVDAIVQVVKANAAYVPPYGSGASLYIRPYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKG 160
Cdd:PRK13357 92 KRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVPPYGEGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPVGAYFKG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 161 GAKPITIKVS-DFDRAAPHGTGHIKAGLNYAMSLHAIVTAHEEGYAENMYLDAATRTKVEETGGANFIFVTKDGKVVTPK 239
Cdd:PRK13357 172 GVKPVSIWVSdEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTYIEEVGGMNFFFITKDGTVTPPL 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 240 SNSILPSITRRSILYVAEHyLGLETEEREVYLDEVKD------FAECGLCGTAAVISPVGKIVDHGKEICFPSGmdEMGP 313
Cdd:PRK13357 252 SGSILPGITRDSLLQLAED-LGLTVEERPVSIDEWQAdaasgeFTEAFACGTAAVITPIGGIKYKDKEFVIGDG--EVGP 328
|
330 340
....*....|....*....|....*...
gi 495645031 314 VIKKLYETLTGIQMGHIEAPEGWIQVVE 341
Cdd:PRK13357 329 VTQKLYDELTGIQFGDVEDPHGWIVKVD 356
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
31-337 |
4.24e-140 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 399.52 E-value: 4.24e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 31 WDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNAKRFADSARRLEMPVFPEDRFVDAIVQVVKA 110
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 111 NAAYVPPYGSGASLYIRPYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKGGAKPITIKVS-DFDRAAPHGTGHIKAGLNY 189
Cdd:TIGR01123 81 NKDWVPPYGSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKGGLAPVSIFVTtEYDRAAPGGTGAVKVGGNY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 190 AMSLHAIVTAHEEGYAENMYLDAATRTKVEETGGANFIFVTKDG-KVVTPKSNSILPSITRRSILYVAEHyLGLETEERE 268
Cdd:TIGR01123 161 AASLLAQAKAAEQGCDQVVYLDPVEHTYIEEVGAMNFFFITGDGeLVTPPLSGSILPGITRDSLLQLAKD-LGMEVEERR 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495645031 269 VYLDEVKDFAECG----LCGTAAVISPVGKIVDHGKEICFPSGmdEMGPVIKKLYETLTGIQMGHIEAPEGWI 337
Cdd:TIGR01123 240 IDIDELKAFVEAGeivfACGTAAVITPVGEIQHGGKEVVFASG--QPGEVTKALYDELTDIQYGDFEDPYGWI 310
|
|
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
48-328 |
2.56e-126 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 363.05 E-value: 2.56e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 48 AGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNAKRFADSARRLEMPVFPEDRFVDAIVQVVKANAAYvPPYGSGASLYIR 127
Cdd:cd01557 6 THALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADW-VPYGGGASLYIR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 128 PYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKGGAKPITIKVSDFDRAAPHGTGHIKAGLNYAMSLHAIVTAHEEGYAEN 207
Cdd:cd01557 85 PFIFGTDPQLGVSPALEYLFAVFASPVGAYFKGGEKGVSALVSSFRRAAPGGPGAAKAGGNYAASLLAQKEAAEKGYDQA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 208 MYLDAAtRTKVEETGGANFIFVtKDGKVVTPKSN-SILPSITRRSILYVAEHyLGLETEEREVYLDEVKDFAECGLCGTA 286
Cdd:cd01557 165 LWLDGA-HGYVAEVGTMNIFFV-KDGELITPPLDgSILPGITRDSILELARD-LGIKVEERPITRDELYEADEVFATGTA 241
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 495645031 287 AVISPVGKIVDHGKEICFPSGmdemGPVIKKLYETLTGIQMG 328
Cdd:cd01557 242 AVVTPVGEIDYRGKEPGEGEV----GPVTKKLYDLLTDIQYG 279
|
|
| PLN02782 |
PLN02782 |
Branched-chain amino acid aminotransferase |
2-336 |
1.42e-98 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 215418 Cd Length: 403 Bit Score: 297.15 E-value: 1.42e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 2 EKKQIDWSSIGFGYIPTEKRYVSN-YKDGKWDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNA 80
Cdd:PLN02782 66 ELADIDWDNLGFGLVPTDYMYIMKcNRDGEFSKGELQRFGNIELSPSAGVLNYGQGLFEGLKAYRKEDGNILLFRPEENA 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 81 KRFADSARRLEMPVFPEDRFVDAIVQVVKANAAYVPPYGSGaSLYIRPYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKG 160
Cdd:PLN02782 146 IRMRNGAERMCMPAPTVEQFVEAVKETVLANKRWVPPPGKG-SLYIRPLLMGSGAVLGLAPAPEYTFLIYVSPVGNYFKE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 161 GAKPITIKVSD-FDRAAPHGTGHIKAGLNYAMSLHAIVTAHEEGYAENMYLDAATRTKVEETGGANfIFVTKDGKVVTPK 239
Cdd:PLN02782 225 GVAPINLIVENeFHRATPGGTGGVKTIGNYAAVLKAQSIAKAKGYSDVLYLDCVHKKYLEEVSSCN-IFIVKDNVISTPA 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 240 -SNSILPSITRRSILYVAEHYlGLETEEREVYLDEVKDFAECGLCGTAAVISPVGKIVDHGKEICFpsGMDEMGPVIKKL 318
Cdd:PLN02782 304 iKGTILPGITRKSIIDVARSQ-GFQVEERNVTVDELLEADEVFCTGTAVVVSPVGSITYKGKRVSY--GEGGFGTVSQQL 380
|
330
....*....|....*...
gi 495645031 319 YETLTGIQMGHIEAPEGW 336
Cdd:PLN02782 381 YTVLTSLQMGLIEDNMNW 398
|
|
| PLN03117 |
PLN03117 |
Branched-chain-amino-acid aminotransferase; Provisional |
6-341 |
2.23e-90 |
|
Branched-chain-amino-acid aminotransferase; Provisional
Pssm-ID: 178664 Cd Length: 355 Bit Score: 274.50 E-value: 2.23e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 6 IDWSSIGFGYIPTEKRYVSNYKDGK-WDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNAKRFA 84
Cdd:PLN03117 20 VKWEELGFALVPTDYMYVAKCKQGEsFSEGKIVPYGDISISPCAGILNYGQGLFEGLKAYRTEDGRITLFRPDQNALRMQ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 85 DSARRLEMPVFPEDRFVDAIVQVVKANAAYVPPYGSGAsLYIRPYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKGGAKp 164
Cdd:PLN03117 100 TGADRLCMTPPSLEQFVEAVKQTVLANKKWVPPPGKGT-LYIRPLLIGSGAVLGVAPAPEYTFLIYASPVGNYHKASSG- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 165 ITIKVSD-FDRAAPHGTGHIKAGLNYAMSLHAIVTAHEEGYAENMYLDAATRTKVEETGGANfIFVTKDGKVVTPK-SNS 242
Cdd:PLN03117 178 LNLKVDHkHRRAHSGGTGGVKSCTNYSPVVKSLIEAKSSGFSDVLFLDAATGKNIEELSACN-IFILKGNIVSTPPtSGT 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 243 ILPSITRRSILYVAeHYLGLETEEREVYLDEVKDFAECGLCGTAAVISPVGKIVDHGKEICFPSGMDEMGpviKKLYETL 322
Cdd:PLN03117 257 ILPGVTRKSISELA-RDIGYQVEERDVSVDELLEAEEVFCTGTAVVVKAVETVTFHDKKVKYRTGEEALS---TKLHLIL 332
|
330
....*....|....*....
gi 495645031 323 TGIQMGHIEAPEGWIQVVE 341
Cdd:PLN03117 333 TNIQMGVVEDKKGWMVEID 351
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
31-332 |
2.68e-87 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 263.97 E-value: 2.68e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 31 WDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYtteDGRIvvFRPDMNAKRFADSARRLEMPV-FPEDRFVDAIVQVVK 109
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAY---DGRL--FRLDEHLARLNRSAKRLGIPIpYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 110 ANAayvppygsGASLYIRPYMFGSNPVIGVKPAD-EYQFRAFVTPVGPYFKGG-AKPITIKVSDFDRAAPHGTGHIKAGl 187
Cdd:COG0115 79 ANG--------LEDGYIRPQVTRGVGGRGVFAEEyEPTVIIIASPLPAYPAEAyEKGVRVITSPYRRAAPGGLGGIKTG- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 188 NYAMSLHAIVTAHEEGYAENMYLDaaTRTKVEETGGANFIFVtKDGKVVTPK-SNSILPSITRRSILYVAEHyLGLETEE 266
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLLD--TDGYVAEGSGSNVFIV-KDGVLVTPPlSGGILPGITRDSVIELARE-LGIPVEE 225
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 495645031 267 REVYLDEVKDFAECGLCGTAAVISPVGKIVDHgkeiCFPSGmdEMGPVIKKLYETLTGIQMGHIEA 332
Cdd:COG0115 226 RPISLEELYTADEVFLTGTAAEVTPVTEIDGR----PIGDG--KPGPVTRRLRELYTDIVRGEAED 285
|
|
| PLPDE_IV |
cd00449 |
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, ... |
50-322 |
1.38e-82 |
|
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate lyases (ADCL). BCAT catalyzes the reversible transamination reaction between the L-branched-chain amino and alpha-keto acids. DAAT catalyzes the synthesis of D-glutamic acid and D-alanine, and ADCL converts 4-amino-4-deoxychorismate to p-aminobenzoate and pyruvate. Except for a few enzymes, i. e., Escherichia coli and Salmonella BCATs, which are homohexamers arranged as a double trimer, the class IV PLPDEs are homodimers. Homodimer formation is required for catalytic activity.
Pssm-ID: 238254 [Multi-domain] Cd Length: 256 Bit Score: 250.98 E-value: 1.38e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 50 VLQYSQSVFEGMKAYttedgRIVVFRPDMNAKRFADSARRLEMPV-FPEDRFVDAIVQVVKANAayvppygsGASLYIRP 128
Cdd:cd00449 3 GLHYGDGVFEGLRAG-----KGRLFRLDEHLDRLNRSAKRLGLPIpYDREELREALKELVAANN--------GASLYIRP 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 129 YMFGSNPVIGV--KPADEYQFRAFVTPVGPYFKGGAKPITIKVSDFDR-AAPHGTGHIKAGlNYAMSLHAIVTAHEEGYA 205
Cdd:cd00449 70 LLTRGVGGLGVapPPSPEPTFVVFASPVGAYAKGGEKGVRLITSPDRRrAAPGGTGDAKTG-GNLNSVLAKQEAAEAGAD 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 206 ENMYLDAATRtkVEETGGANFIFVtKDGKVVTPKSNS-ILPSITRRSILYVAEHyLGLETEEREVYLDEVKDFAECGLCG 284
Cdd:cd00449 149 EALLLDDNGY--VTEGSASNVFIV-KDGELVTPPLDGgILPGITRDSVIELAKE-LGIKVEERPISLDELYAADEVFLTG 224
|
250 260 270
....*....|....*....|....*....|....*...
gi 495645031 285 TAAVISPVGKIVDHGKeicfpsGMDEMGPVIKKLYETL 322
Cdd:cd00449 225 TAAEVTPVTEIDGRGI------GDGKPGPVTRKLRELL 256
|
|
| PLN02259 |
PLN02259 |
branched-chain-amino-acid aminotransferase 2 |
2-337 |
1.74e-79 |
|
branched-chain-amino-acid aminotransferase 2
Pssm-ID: 177901 Cd Length: 388 Bit Score: 247.71 E-value: 1.74e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 2 EKKQIDWSSIGFGYIPTEKRYVSN-YKDGKWDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNA 80
Cdd:PLN02259 52 VYADLDWDNLGFGLNPADYMYVMKcSKDGEFTQGELSPYGNIQLSPSAGVLNYGQAIYEGTKAYRKENGKLLLFRPDHNA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 81 KRFADSARRLEMPVFPEDRFVDAIVQVVKANAAYVPPYGSGaSLYIRPYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKG 160
Cdd:PLN02259 132 IRMKLGAERMLMPSPSVDQFVNAVKQTALANKRWVPPAGKG-TLYIRPLLMGSGPILGLGPAPEYTFIVYASPVGNYFKE 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 161 GAKPITIKV-SDFDRAAPHGTGHIKAGLNYAMSLHAIVTAHEEGYAENMYLDAATRTKVEETGGANfIFVTKDGKVVTPK 239
Cdd:PLN02259 211 GMAALNLYVeEEYVRAAPGGAGGVKSITNYAPVLKALSRAKSRGFSDVLYLDSVKKKYLEEASSCN-VFVVKGRTISTPA 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 240 SN-SILPSITRRSILYVAEHYlGLETEEREVYLDEVKDFAECGLCGTAAVISPVGKIVDHGKEICFPSgMDEmgPVIKKL 318
Cdd:PLN02259 290 TNgTILEGITRKSVMEIASDQ-GYQVVEKAVHVDEVMDADEVFCTGTAVVVAPVGTITYQEKRVEYKT-GDE--SVCQKL 365
|
330
....*....|....*....
gi 495645031 319 YETLTGIQMGHIEAPEGWI 337
Cdd:PLN02259 366 RSVLVGIQTGLIEDNKGWV 384
|
|
| PLN02883 |
PLN02883 |
Branched-chain amino acid aminotransferase |
2-337 |
7.64e-70 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 178471 Cd Length: 384 Bit Score: 222.67 E-value: 7.64e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 2 EKKQIDWSSIGFGYIPTEKRYVS-NYKDGKWDDGCLTEDANIVLNECAGVLQYSQSVFEGMKAYTTEDGRIVVFRPDMNA 80
Cdd:PLN02883 48 EYADVDWDKLGFSLVRTDFMFATkSCRDGNFEQGYLSRYGNIELNPAAGILNYGQGLIEGMKAYRGEDGRILLFRPELNA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 81 KRFADSARRLEMPVFPEDRFVDAIVQVVKANAAYVPPYGSGaSLYIRPYMFGSNPVIGVKPADEYQFRAFVTPVGPYFKG 160
Cdd:PLN02883 128 MRMKIGAERMCMHSPSVHQFIEGVKQTVLANRRWVPPPGKG-SLYLRPLLFGSGASLGVAAAPEYTFLVFGSPVQNYFKE 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 161 GAKPITIKVSD-FDRAAPHGTGHIKAGLNYAMSLHAIVTAHEEGYAENMYLDAATRTKVEETGGANfIFVTKDGKVVTP- 238
Cdd:PLN02883 207 GTAALNLYVEEvIPRAYLGGTGGVKAISNYGPVLEVMRRAKSRGFSDVLYLDADTGKNIEEVSAAN-IFLVKGNIIVTPa 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 239 KSNSILPSITRRSILYVAEHyLGLETEEREVYLDEVKDFAECGLCGTAAVISPVGKIVDHGKEICFPSGmdeMGPVIKKL 318
Cdd:PLN02883 286 TSGTILGGITRKSIIEIALD-LGYKVEERRVPVEELKEAEEVFCTGTAAGVASVGSITFKNTRTEYKVG---DGIVTQQL 361
|
330
....*....|....*....
gi 495645031 319 YETLTGIQMGHIEAPEGWI 337
Cdd:PLN02883 362 RSILLGIQTGSIQDTKDWV 380
|
|
| PRK06606 |
PRK06606 |
branched-chain amino acid transaminase; |
31-340 |
3.92e-50 |
|
branched-chain amino acid transaminase;
Pssm-ID: 235841 Cd Length: 306 Bit Score: 169.17 E-value: 3.92e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 31 WDDGCLT--EDANI-VLNEcagVLQYSQSVFEGMKAYTTEDGRiVVFRPDMNAKRFADSARRLEMPV-FPEDRFVDAIVQ 106
Cdd:PRK06606 10 WFNGELVpwEDAKVhVLTH---ALHYGTGVFEGIRAYDTPKGP-AIFRLREHTKRLFNSAKILRMEIpYSVDELMEAQRE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 107 VVKANAAyvppygsgASLYIRPYMFGSNPVIGVKPAD-EYQFRAFVTPVGPYF--KGGAKPITIKVSDFDRAAPHGT-GH 182
Cdd:PRK06606 86 VVRKNNL--------KSAYIRPLVFVGDEGLGVRPHGlPTDVAIAAWPWGAYLgeEALEKGIRVKVSSWTRHAPNSIpTR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 183 IKAGLNYAMSLHAIVTAHEEGYAENMYLDaaTRTKVEETGGANfIFVTKDGKVVTPK-SNSILPSITRRSILYVAEHyLG 261
Cdd:PRK06606 158 AKASGNYLNSILAKTEARRNGYDEALLLD--VEGYVSEGSGEN-IFIVRDGVLYTPPlTSSILEGITRDTVITLAKD-LG 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495645031 262 LETEEREVYLDEVKDFAECGLCGTAAVISPVgKIVDHgkeicFPSGMDEMGPVIKKLYETLTGIQMGHIEAPEGWIQVV 340
Cdd:PRK06606 234 IEVIERRITRDELYIADEVFFTGTAAEVTPI-REVDG-----RQIGNGKRGPITEKLQSAYFDIVRGRTEKYAHWLTPV 306
|
|
| ilvE_I |
TIGR01122 |
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are ... |
31-340 |
4.15e-42 |
|
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family more strongly similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130192 Cd Length: 298 Bit Score: 148.28 E-value: 4.15e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 31 WDDGCLT--EDANI-VLNEcagVLQYSQSVFEGMKAYTTEDGrIVVFRPDMNAKRFADSARRLEMPV-FPEDRFVDAIVQ 106
Cdd:TIGR01122 1 WMDGEFVdwEDAKVhVLTH---ALHYGTGVFEGIRAYDTDKG-PAIFRLKEHIQRLYDSAKIYRMEIpYSKEELMEATRE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 107 VVKANAAyvppygsgASLYIRPYMFGSNPVIGVKPADEYQFRAFVT--PVGPYF--KGGAKPITIKVSDFDRAAPHGT-G 181
Cdd:TIGR01122 77 TLRKNNL--------RSAYIRPLVFRGDGDLGLNPRAGYKPDVIIAawPWGAYLgeEALEKGIDAKVSSWRRNAPNTIpT 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 182 HIKAGLNYAMSLHAIVTAHEEGYAENMYLDaaTRTKVEETGGANfIFVTKDGKVVTPK-SNSILPSITRRSILYVAeHYL 260
Cdd:TIGR01122 149 AAKAGGNYLNSLLAKSEARRHGYDEAILLD--VEGYVAEGSGEN-IFIVKDGVLFTPPvTSSILPGITRDTVITLA-KEL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 261 GLETEEREVYLDEVKDFAECGLCGTAAVISPVgKIVDhGKEIcfpsGMDEMGPVIKKLYETLTGIQMGHIEAPEGWIQVV 340
Cdd:TIGR01122 225 GIEVVEQPISREELYTADEAFFTGTAAEITPI-REVD-GRKI----GNGRRGPVTKKLQEAFFDLVTGGTEDYWGWLTYV 298
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
56-295 |
1.48e-34 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 125.93 E-value: 1.48e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 56 SVFEGMKAYtteDGRIvvFRPDMNAKRFADSARRLEMPV-FPEDRFVDAIVQVVKANAAYVPpygsgaslYIRPYMFGSN 134
Cdd:pfam01063 1 GVFETLRVY---NGKI--FFLDEHLARLRRSAKLLGIPLpFDEEDLRKIIEELLKANGLGVG--------RLRLTVSRGP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 135 PVIGvKPADEYQFRAFVTPVGPYFKGGAKPITIKVSDFDRAAPHGTghIKaGLNYAMSLHAIVTAHEEGYAENMYLDAAT 214
Cdd:pfam01063 68 GGFG-LPTSDPTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLPG--AK-TLNYLENVLARREAKAQGADDALLLDEDG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 215 RtkVEETGGANfIFVTKDGKVVTPK-SNSILPSITRRSILYVAEHyLGLETEEREVYLDEVKDFAECGLCGTAAVISPVG 293
Cdd:pfam01063 144 N--VTEGSTSN-VFLVKGGTLYTPPlESGILPGITRQALLDLAKA-LGLEVEERPITLADLQEADEAFLTNSLRGVTPVS 219
|
..
gi 495645031 294 KI 295
Cdd:pfam01063 220 SI 221
|
|
| PRK07544 |
PRK07544 |
branched-chain amino acid aminotransferase; Validated |
27-298 |
2.19e-30 |
|
branched-chain amino acid aminotransferase; Validated
Pssm-ID: 181025 Cd Length: 292 Bit Score: 117.00 E-value: 2.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 27 KDGK-WDDGCLTE--DANI-VLNECagvLQYSQSVFEGMKAYtteDGRIvvFRPDMNAKRFADSARRLEMPV-FPEDRFV 101
Cdd:PRK07544 7 RDGFiWMDGELVPwrDAKVhVLTHG---LHYASSVFEGERAY---GGKI--FKLREHSERLRRSAELLDFEIpYSVAEID 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 102 DAIVQVVKANAAyvppygsgASLYIRPYMFGSNPVIGVK-PADEYQFRAFVTPVGPYFKGGAKP--ITIKVSDFDRAAPH 178
Cdd:PRK07544 79 AAKKETLAANGL--------TDAYVRPVAWRGSEMMGVSaQQNKIHLAIAAWEWPSYFDPEAKMkgIRLDIAKWRRPDPE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 179 GT-GHIKAGLNY---AMSLHAivtAHEEGYAENMYLDaaTRTKVEETGGANfIFVTKDGKVVTPKSNSILPSITRRSILY 254
Cdd:PRK07544 151 TApSAAKAAGLYmicTISKHA---AEAKGYADALMLD--YRGYVAEATGAN-IFFVKDGVIHTPTPDCFLDGITRQTVIE 224
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 495645031 255 VAEHYlGLETEEREVYLDEVKDFAECGLCGTAAVISPVGKIVDH 298
Cdd:PRK07544 225 LAKRR-GIEVVERHIMPEELAGFSECFLTGTAAEVTPVSEIGEY 267
|
|
| D-AAT_like |
cd01558 |
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes ... |
50-320 |
2.48e-26 |
|
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and D-glutamate in addition to other D-amino acids. The enzyme like other members of this superfamily requires PLP as a cofactor. Members of this subgroup are found in all three forms of life.
Pssm-ID: 238799 [Multi-domain] Cd Length: 270 Bit Score: 105.37 E-value: 2.48e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 50 VLQYSQSVFEGMKAYtteDGRivVFRPDMNAKRFADSARRLEMP-VFPEDRFVDAIVQVVKANAayvppyGSGASLYIRP 128
Cdd:cd01558 20 GFLFGDGVYEVIRVY---NGK--PFALDEHLDRLYRSAKELRIDiPYTREELKELIRELVAKNE------GGEGDVYIQV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 129 YMfgsnpviGVKPADeYQFRAFVTPV------------GPYFKGGAKPITIKVSDFDRAAphgtghIKAgLNYAMSLHAI 196
Cdd:cd01558 89 TR-------GVGPRG-HDFPKCVKPTvviitqplplppAELLEKGVRVITVPDIRWLRCD------IKS-LNLLNNVLAK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 197 VTAHEEGYAENMYLDAATRtkVEETGGANfIFVTKDGKVVT-PKSNSILPSITRRSILYVAEHyLGLETEEREVYLDEVK 275
Cdd:cd01558 154 QEAKEAGADEAILLDADGL--VTEGSSSN-VFIVKNGVLVTpPLDNGILPGITRATVIELAKE-LGIPVEERPFSLEELY 229
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 495645031 276 DFAECGLCGTAAVISPVGKIvDhGKEIcfpsGMDEMGPVIKKLYE 320
Cdd:cd01558 230 TADEVFLTSTTAEVMPVVEI-D-GRPI----GDGKPGPVTKRLRE 268
|
|
| ADCL_like |
cd01559 |
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent ... |
51-303 |
7.92e-18 |
|
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.
Pssm-ID: 238800 [Multi-domain] Cd Length: 249 Bit Score: 81.59 E-value: 7.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 51 LQYSQSVFEGMKAYtteDGRIVVFrpDMNAKRFADSARRLEMPVFPEDRFVDAIVQVVKANaayvpPYGSGAslyIR--- 127
Cdd:cd01559 4 FAYGDGVFETMRAL---DGRLFLL--DAHLARLERSARRLGIPEPDLPRLRAALESLLAAN-----DIDEGR---IRlil 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 128 ---PYMFGSNPVIGVKPAdeyqFRAFVTPVGPyfKGGAKPITIKVSDFDRAAPHGTGHIKAgLNYAMSLHAIVTAHEEGY 204
Cdd:cd01559 71 srgPGGRGYAPSVCPGPA----LYVSVIPLPP--AWRQDGVRLITCPVRLGEQPLLAGLKH-LNYLENVLAKREARDRGA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 205 AENMYLDAATRtkVEETGGANfIFVTKDGKVVTPK-SNSILPSITRRSILYVAEHyLGLETEEREVYLDEVKDFAECGLC 283
Cdd:cd01559 144 DEALFLDTDGR--VIEGTASN-LFFVKDGELVTPSlDRGGLAGITRQRVIELAAA-KGYAVDERPLRLEDLLAADEAFLT 219
|
250 260
....*....|....*....|
gi 495645031 284 GTAAVISPVGKIVDHGKEIC 303
Cdd:cd01559 220 NSLLGVAPVTAIDDHDGPPG 239
|
|
| PRK06680 |
PRK06680 |
D-amino acid aminotransferase; Reviewed |
199-320 |
1.80e-16 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 180656 [Multi-domain] Cd Length: 286 Bit Score: 78.43 E-value: 1.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 199 AHEEGYAENMYLDAATrtkVEETGGANFIFVTKDGKVVT-PKSNSILPSITRRSILYVAEHyLGLETEEREVYLDEVKDF 277
Cdd:PRK06680 163 AKEAGAQEAWMVDDGF---VTEGASSNAWIVTKDGKLVTrPADNFILPGITRHTLIDLAKE-LGLEVEERPFTLQEAYAA 238
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 495645031 278 AECGLCGTAAVISPVGKIVDHgkeicfPSGMDEMGPVIKKLYE 320
Cdd:PRK06680 239 REAFITAASSFVFPVVQIDGK------QIGNGKPGPIAKRLRE 275
|
|
| PRK08320 |
PRK08320 |
branched-chain amino acid aminotransferase; Reviewed |
53-320 |
5.58e-16 |
|
branched-chain amino acid aminotransferase; Reviewed
Pssm-ID: 236238 [Multi-domain] Cd Length: 288 Bit Score: 76.83 E-value: 5.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 53 YSQSVFEGMKAYtteDGRivVFRPDMNAKRFADSAR--RLEMPVfPEDRFVDAIVQVVKANaayvppygsgaSL---YIR 127
Cdd:PRK08320 28 YGDGVFEGIRAY---NGR--VFRLKEHIDRLYDSAKaiMLEIPL-SKEEMTEIVLETLRKN-----------NLrdaYIR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 128 PYM------FGSNPVIGVKPadeyQFRAFVTPVGPYFKG----GAKPITIKVSdfdRAAPHGTG-HIKAgLNYAMSLHAI 196
Cdd:PRK08320 91 LVVsrgvgdLGLDPRKCPKP----TVVCIAEPIGLYPGElyekGLKVITVSTR---RNRPDALSpQVKS-LNYLNNILAK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 197 VTAHEEGYAENMYLDaaTRTKVEETGGANfIFVTKDGKVVTP-KSNSILPSITRRSILYVAEHyLGLETEEREVYLDEVK 275
Cdd:PRK08320 163 IEANLAGVDEAIMLN--DEGYVAEGTGDN-IFIVKNGKLITPpTYAGALEGITRNAVIEIAKE-LGIPVREELFTLHDLY 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 495645031 276 DFAECGLCGTAAVISPVGKiVDhGKEIcfpsGMDEMGPVIKKLYE 320
Cdd:PRK08320 239 TADEVFLTGTAAEVIPVVK-VD-GRVI----GDGKPGPITKKLLE 277
|
|
| PRK12479 |
PRK12479 |
branched-chain-amino-acid transaminase; |
53-320 |
4.50e-13 |
|
branched-chain-amino-acid transaminase;
Pssm-ID: 183549 [Multi-domain] Cd Length: 299 Bit Score: 68.83 E-value: 4.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 53 YSQSVFEGMKAYTTEdgrivVFRPDMNAKRFADSARR--LEMPVFPEDrFVDAIVQVVKANAAyvppygsgASLYIR--- 127
Cdd:PRK12479 29 YGDGVFEGIRSYGGN-----VFCLKEHVKRLYESAKSilLTIPLTVDE-MEEAVLQTLQKNEY--------ADAYIRliv 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 128 ---PYMFGSNPVIGVKP-----ADeyQFRAFVTPvgpYFKGGAKPITIKVSdfdRAAPHGTGHIKAGLNYAMSLHAIVTA 199
Cdd:PRK12479 95 srgKGDLGLDPRSCVKPsviiiAE--QLKLFPQE---FYDNGLSVVSVASR---RNTPDALDPRIKSMNYLNNVLVKIEA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 200 HEEGYAENMYLDaaTRTKVEETGGANfIFVTKDGKVVTPKSN-SILPSITRRSILYVAEHyLGLETEEREVYLDEVKDFA 278
Cdd:PRK12479 167 AQAGVLEALMLN--QQGYVCEGSGDN-VFVVKDGKVLTPPSYlGALEGITRNSVIELCER-LSIPCEERPFTRHDVYVAD 242
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 495645031 279 ECGLCGTAAVISPVGKIvdHGKEIcfpsGMDEMGPVIKKLYE 320
Cdd:PRK12479 243 EVFLTGTAAELIPVVKV--DSREI----GDGKPGSVTKQLTE 278
|
|
| PRK13356 |
PRK13356 |
branched-chain amino acid aminotransferase; |
56-320 |
2.03e-09 |
|
branched-chain amino acid aminotransferase;
Pssm-ID: 237362 Cd Length: 286 Bit Score: 57.66 E-value: 2.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 56 SVFEGMKAYtteDGrivvFRPDMNA--KRFADSARRLEM-PVFPEDRFVDAIVQVVKAnaayvppYGSGASLYIRPYMFG 132
Cdd:PRK13356 35 TVFDGARAF---EG----VTPDLDLhcARVNRSAEALGLkPTVSAEEIEALAREGLKR-------FDPDTALYIRPMYWA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 133 SNPVIGVKPADEYQFR----AFVTPVGPyfkggAKPITIKVSDFDRAAPH-GTGHIKAGLNYAMSLHAIVTAHEEGYAEN 207
Cdd:PRK13356 101 EDGFASGVAPDPESTRfalcLEEAPMPE-----PTGFSLTLSPFRRPTLEmAPTDAKAGCLYPNNARALREARSRGFDNA 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 208 MYLDAATrtKVEETGGANfIFVTKDGKVVTPKSN-SILPSITR-RSILYVAEHylGLETEEREVYLDEVKDFAECGLCGT 285
Cdd:PRK13356 176 LVLDMLG--NVAETATSN-VFMVKDGVVFTPVPNgTFLNGITRqRVIALLRED--GVTVVETTLTYEDFLEADEVFSTGN 250
|
250 260 270
....*....|....*....|....*....|....*
gi 495645031 286 AAVISPVGKIVDhgKEIcfpsgmdEMGPVIKKLYE 320
Cdd:PRK13356 251 YSKVVPVTRFDD--RSL-------QPGPVTRRARE 276
|
|
| PLN02845 |
PLN02845 |
Branched-chain-amino-acid aminotransferase-like protein |
186-322 |
1.24e-08 |
|
Branched-chain-amino-acid aminotransferase-like protein
Pssm-ID: 215454 [Multi-domain] Cd Length: 336 Bit Score: 55.79 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 186 GLNYAMSLHAIVTAHEEGYAENMYLDAatRTKVEETGGANFIFVTKDGKVVTPKSNSILPSITRRSILYVAEHYLGL--- 262
Cdd:PLN02845 186 SVNYLPNALSQMEAEERGAFAGIWLDE--EGFVAEGPNMNVAFLTNDGELVLPPFDKILSGCTARRVLELAPRLVSPgdl 263
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495645031 263 -ETEEREVYLDEVKDFAECGLCGTAAVISPV----GKIVDHGKEicfpsgmdemGPVIKKLYETL 322
Cdd:PLN02845 264 rGVKQRKISVEEAKAADEMMLIGSGVPVLPIvswdGQPIGDGKV----------GPITLALHDLL 318
|
|
| PRK06092 |
PRK06092 |
4-amino-4-deoxychorismate lyase; Reviewed |
203-325 |
3.49e-03 |
|
4-amino-4-deoxychorismate lyase; Reviewed
Pssm-ID: 235696 Cd Length: 268 Bit Score: 38.67 E-value: 3.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495645031 203 GYAENMYLDAATRtkVEETGGANfIFVTKDGKVVTPK-SNSILPSITRRSILYVAEHyLGLETEEREVYLDEVKDFAECG 281
Cdd:PRK06092 158 EADEALVLDSEGW--VIECCAAN-LFWRKGGVVYTPDlDQCGVAGVMRQFILELLAQ-SGYPVVEVDASLEELLQADEVF 233
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 495645031 282 LCGTAAVISPVGKIvdhgKEICFPSGmdemgpvikKLYETLTGI 325
Cdd:PRK06092 234 ICNSLMPVWPVRAI----GETSYSSG---------TLTRYLQPL 264
|
|
| |
