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Conserved domains on  [gi|495776716|ref|WP_008501295|]
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MULTISPECIES: virulence factor SrfB [Enterobacter]

Protein Classification

virulence factor SrfB( domain architecture ID 10008567)

virulence factor SrfB is the product of a gene activated by the SsrAB two-component regulatory system

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SrfB COG4457
Virulence factor SrfB-related protein [Secondary metabolites biosynthesis, transport and ...
1-993 0e+00

Virulence factor SrfB-related protein [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 443555  Cd Length: 998  Bit Score: 1769.45  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716   1 MLVNLCDYKQSVTLIANSGVQFLDFGLTPQ-DSASNGRFVRKTANGPLLRLDFDLVNGRYTLPGMNGGQPEVVKPETTIP 79
Cdd:COG4457    1 MLAELTDYKQEITLIPNSGIQFLDFGLDLDaRPELSGRFVRRSANGPLLRLLYDEESDKFLLPAPPGGAPEVVDPEYSIS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  80 LHQSLAVLDGVWLPVPFLRFNPPRTFVEGPDNWARVQVRKLDTPDTAGNTHRVTLALDSQIA--DHATSALSPVENDILN 157
Cdd:COG4457   81 LEQSLKLLDGVWLPLPFLRFNPPRRFDQGPDNWARVRIVELETPDDDGNTHRVTLAFDTKLVadDQNTAYLAPTEEDVRN 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 158 GTRFALAWRDNEVDSFLDQTWIDGWLREAFTQYADGVENRSERDLQQAMRSFEYQAHWLNLLTMLGEQLTVPEVKFVTHT 237
Cdd:COG4457  161 GASFALAWRNDEMAWFLDQTWVDGWLREVFKEFARERERRSEEDIEDALRQFEHQAHYLNLLSLLGSQLRVPEIKIVTTT 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 238 LS--TPAIPVDLILDVGNTHTCGVIIEDHGDANDGLRQTAELQVRSLSEPQFLNEPLFTSRLEFSEARFGKQHFSVESGR 315
Cdd:COG4457  241 LQdiVPAIPVDLVLDVGNSRTCGILIEDHPQENDGLKQSYELQLRDLSRPELVYNEPFESRVEFAQARFGKEHFSVESGR 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 316 EDAFVWPSIVRVGDEARKLAMQRLGTEGNSGISSPRRYLWDETPVVQDWRFSQMNSKTQREPLATAFPLMNLMNDDGEPL 395
Cdd:COG4457  321 RDAFVWPSIVRVGPEASRLAQRREGTEGSTGLSSPKRYLWDEDPYEQGWRFNQAYDKSDREPLATAAPLMRLINDRGEPL 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 396 FTLPQDERLPVFSPQYSRSTLMTHMLCELLAQALGQINSVATRLRLGFPASPRQLRTLILTLPSAMPKQEREIFRRRMFE 475
Cdd:COG4457  401 YQLPEDERLPVFSPHYSRSSLMTFMLSEVLAQALMQINSPAQRLRMGHSDAPRRLRSIILTLPSAMPKPEREIFRSRMEQ 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 476 AIAIVWKAMGWHPQDEDFVTRKQQEKSVVPVPEIQMEWDEASCGQLVWLYNEAISRFGGQTEAFFASLARPDREPEpGSQ 555
Cdd:COG4457  481 AIGLVWKSMGWHPGDDDFSTPEDKEKSWVPVPEVQVEWDEATCGQLVYLYNETQVNFGGRIEEFFASLARPDKQPD-GEA 559
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 556 PGRALRVASIDIGGGTTDMAITHYQLDDGSGNNVKITPQLLFREGFKVAGDDTLLDVIQRYVLPALQTQLQKSGIADASL 635
Cdd:COG4457  560 PGRTLRIASIDIGGGTTDLAITDYRLDDGVGSNVKITPEQLFREGFKVAGDDILLDVIQRYVLPALQAALKKAGVADAAS 639
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 636 LMASLFGDSGRIDTQAVLRQQTALQLFMPIGHAILAGWESSDVDDPLAGLHATFGDLLP-QKPTRNVMNYLQQAIdHALP 714
Cdd:COG4457  640 LLSRLFGGEGRSDQDAVLRQQLTLQVFMPLALAILSAYEQYDPLDRSAEISATFGELLElQPPTDKVLDYVNQAI-RREP 718
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 715 AGSDAFDLFAVPLHVNFREMQDAMLAGQFTLASPLHAVCEAISHYSCDILLITGRPGCLPGVQALIRHLQPVPVNRIVWL 794
Cdd:COG4457  719 AGAPPFDLLDVPLQIDLSDLHEAFLSGRMSICKPLRALCEVISHYDCDVLLLTGRPSRLPGVQALFRHLQPVPPNRILPL 798
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 795 DKYQVHEWYPFSQQGRIGNPKSTAAVGAMLCSLALDLRLPRFNFKAADIGAYSTVRYLGVLDNTvNTLREENVWYQDIDL 874
Cdd:COG4457  799 HGYRTGGWYPFHKNGRIDDPKSTAAVGAMLCLLSLDLRLPNFYFKAGDFQPYSTVRYLGLLDNN-NTLKDENVYYRDIDL 877
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 875 DKPGAKLDARLHFPLRGNVTLGFRQLANARWPATPLYTLSINSAELAKAIAGDGVLNVRLKL--CGGSKQEGPEAFELSD 952
Cdd:COG4457  878 DDPDYTLDAEASFEMRGPVRLGFRQLDNERWPASPLYTLTINNPELARKIAGDGVLRVTLAVdkAKGRKEAGPERFEIAD 957
                        970       980       990      1000
                 ....*....|....*....|....*....|....*....|.
gi 495776716 953 AWLQDGTPVAPDALTFKLNTLADRRHSGSHYWIDSGSVYLK 993
Cdd:COG4457  958 AELSDGTPVPLRDLRLKLNTLADSGSGDSHYWLDSGSVYIK 998
 
Name Accession Description Interval E-value
SrfB COG4457
Virulence factor SrfB-related protein [Secondary metabolites biosynthesis, transport and ...
1-993 0e+00

Virulence factor SrfB-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443555  Cd Length: 998  Bit Score: 1769.45  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716   1 MLVNLCDYKQSVTLIANSGVQFLDFGLTPQ-DSASNGRFVRKTANGPLLRLDFDLVNGRYTLPGMNGGQPEVVKPETTIP 79
Cdd:COG4457    1 MLAELTDYKQEITLIPNSGIQFLDFGLDLDaRPELSGRFVRRSANGPLLRLLYDEESDKFLLPAPPGGAPEVVDPEYSIS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  80 LHQSLAVLDGVWLPVPFLRFNPPRTFVEGPDNWARVQVRKLDTPDTAGNTHRVTLALDSQIA--DHATSALSPVENDILN 157
Cdd:COG4457   81 LEQSLKLLDGVWLPLPFLRFNPPRRFDQGPDNWARVRIVELETPDDDGNTHRVTLAFDTKLVadDQNTAYLAPTEEDVRN 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 158 GTRFALAWRDNEVDSFLDQTWIDGWLREAFTQYADGVENRSERDLQQAMRSFEYQAHWLNLLTMLGEQLTVPEVKFVTHT 237
Cdd:COG4457  161 GASFALAWRNDEMAWFLDQTWVDGWLREVFKEFARERERRSEEDIEDALRQFEHQAHYLNLLSLLGSQLRVPEIKIVTTT 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 238 LS--TPAIPVDLILDVGNTHTCGVIIEDHGDANDGLRQTAELQVRSLSEPQFLNEPLFTSRLEFSEARFGKQHFSVESGR 315
Cdd:COG4457  241 LQdiVPAIPVDLVLDVGNSRTCGILIEDHPQENDGLKQSYELQLRDLSRPELVYNEPFESRVEFAQARFGKEHFSVESGR 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 316 EDAFVWPSIVRVGDEARKLAMQRLGTEGNSGISSPRRYLWDETPVVQDWRFSQMNSKTQREPLATAFPLMNLMNDDGEPL 395
Cdd:COG4457  321 RDAFVWPSIVRVGPEASRLAQRREGTEGSTGLSSPKRYLWDEDPYEQGWRFNQAYDKSDREPLATAAPLMRLINDRGEPL 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 396 FTLPQDERLPVFSPQYSRSTLMTHMLCELLAQALGQINSVATRLRLGFPASPRQLRTLILTLPSAMPKQEREIFRRRMFE 475
Cdd:COG4457  401 YQLPEDERLPVFSPHYSRSSLMTFMLSEVLAQALMQINSPAQRLRMGHSDAPRRLRSIILTLPSAMPKPEREIFRSRMEQ 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 476 AIAIVWKAMGWHPQDEDFVTRKQQEKSVVPVPEIQMEWDEASCGQLVWLYNEAISRFGGQTEAFFASLARPDREPEpGSQ 555
Cdd:COG4457  481 AIGLVWKSMGWHPGDDDFSTPEDKEKSWVPVPEVQVEWDEATCGQLVYLYNETQVNFGGRIEEFFASLARPDKQPD-GEA 559
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 556 PGRALRVASIDIGGGTTDMAITHYQLDDGSGNNVKITPQLLFREGFKVAGDDTLLDVIQRYVLPALQTQLQKSGIADASL 635
Cdd:COG4457  560 PGRTLRIASIDIGGGTTDLAITDYRLDDGVGSNVKITPEQLFREGFKVAGDDILLDVIQRYVLPALQAALKKAGVADAAS 639
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 636 LMASLFGDSGRIDTQAVLRQQTALQLFMPIGHAILAGWESSDVDDPLAGLHATFGDLLP-QKPTRNVMNYLQQAIdHALP 714
Cdd:COG4457  640 LLSRLFGGEGRSDQDAVLRQQLTLQVFMPLALAILSAYEQYDPLDRSAEISATFGELLElQPPTDKVLDYVNQAI-RREP 718
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 715 AGSDAFDLFAVPLHVNFREMQDAMLAGQFTLASPLHAVCEAISHYSCDILLITGRPGCLPGVQALIRHLQPVPVNRIVWL 794
Cdd:COG4457  719 AGAPPFDLLDVPLQIDLSDLHEAFLSGRMSICKPLRALCEVISHYDCDVLLLTGRPSRLPGVQALFRHLQPVPPNRILPL 798
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 795 DKYQVHEWYPFSQQGRIGNPKSTAAVGAMLCSLALDLRLPRFNFKAADIGAYSTVRYLGVLDNTvNTLREENVWYQDIDL 874
Cdd:COG4457  799 HGYRTGGWYPFHKNGRIDDPKSTAAVGAMLCLLSLDLRLPNFYFKAGDFQPYSTVRYLGLLDNN-NTLKDENVYYRDIDL 877
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 875 DKPGAKLDARLHFPLRGNVTLGFRQLANARWPATPLYTLSINSAELAKAIAGDGVLNVRLKL--CGGSKQEGPEAFELSD 952
Cdd:COG4457  878 DDPDYTLDAEASFEMRGPVRLGFRQLDNERWPASPLYTLTINNPELARKIAGDGVLRVTLAVdkAKGRKEAGPERFEIAD 957
                        970       980       990      1000
                 ....*....|....*....|....*....|....*....|.
gi 495776716 953 AWLQDGTPVAPDALTFKLNTLADRRHSGSHYWIDSGSVYLK 993
Cdd:COG4457  958 AELSDGTPVPLRDLRLKLNTLADSGSGDSHYWLDSGSVYIK 998
SrfB pfam07520
Virulence factor SrfB; This family includes homologs of SsrAB is a two-component regulatory ...
8-991 0e+00

Virulence factor SrfB; This family includes homologs of SsrAB is a two-component regulatory system encoded within the Salmonella pathogenicity island SPI-2. Among the products of genes activated by SsrAB within epithelial and macrophage cells is Swiss:Q9KIJ9. homologs are found in several other proteobacteria.


Pssm-ID: 429510  Cd Length: 979  Bit Score: 1497.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716    8 YKQSVTLIANSGVQFLDFGLTPQ-DSASNGRFVRKTANGPLLRLDFDLVNGRYTLPGmnGGQPEVVKPET--TIPLHQSL 84
Cdd:pfam07520   1 YKQEVTLIPNSGIQFLDFGLTLDlRREPAGRFVRKSANGPLLRLSYDEERGRYFLPG--LAEPEVVRPEDeySVSLRQSL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716   85 AVLDGVWLPVPFLRFNPPRTFVEGPDNWARVQVRKLDTPDTAGNTHRVTLALDSQIAD--HATSALSPVENDILNGTRFA 162
Cdd:pfam07520  79 ELLDGVWLPLPFFRFNPPRRFDPGPTNWARVRIVALPTPDEDGNTHRVVLAFDTRVMAeeEGMAYLAPTPDDVKNGRSFR 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  163 LAWRDNEVDSFLDQTWIDGWLREAFTQYADGVENRSERDLQQamRSFEYQAHWLNLLTMLGEQLTVPEVKFVTHTLST-- 240
Cdd:pfam07520 159 LASRSEEMSWFLDQTWVDDWLREVFTEQAQQRLKRPRRDILP--REFEHQAHYLNLLDLLGAALALPEIKLVNNTADEiv 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  241 PAIPVDLILDVGNTHTCGVIIEDHGDANDGLRQTAELQVRSLSEPQFLNEPLFTSRLEFSEARFGKQHFSVESGREDAFV 320
Cdd:pfam07520 237 TPIDVDLVLDVGNSRTCGILIEDHPQESDGLKQSYELELRDLSRPEYLYSEPFESRVEFAQARFGKEHFSVRSGRDDAFV 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  321 WPSIVRVGDEARKLAMQRLGTEGNSGISSPRRYLWDETPVVQDWRFSQMNSKTQREPLATAFPLMNLMNDDGEPLFTLPQ 400
Cdd:pfam07520 317 WPSIVRVGPEAARLASLRRGTEGSTGLSSPKRYLWDEEAYEQGWRFNQAYVKGDQEPLATAAPLTRLINDLGEPLHQLPT 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  401 DERLPVFSPQYSRSTLMTHMLCELLAQALGQINSVATRLRLGFPASPRQLRTLILTLPSAMPKQEREIFRRRMFEAIAIV 480
Cdd:pfam07520 397 DERLPVFRPHYSRSSLMTFMLAEVLAQALMQINSPAQRLRRGHSDLPRRLRRIILTVPTAMPKPEREIFRQRAKQALALV 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  481 WKAMGWHPQDEDFVTRKQQEKSVVPVPEIQMEWDEASCGQLVWLYNEAISRFGGQTEAFFASLARPDREPEPGSqpgraL 560
Cdd:pfam07520 477 WKSLGWHPADDDFTPAKDKGKSWVPLPEVQMEWDEATCGQLVYLYNEVQQKFGGRAEEFFALLARPDKAGRPPS-----L 551
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  561 RVASIDIGGGTTDMAITHYQLDDGSGNNVKITPQLLFREGFKVAGDDTLLDVIQRYVLPALQTQLQKSGIADASLLMASL 640
Cdd:pfam07520 552 RVASIDIGGGTTDLVITDYRLDDGAGANVTITPEQRFRDGFKVAGDDILLDVIQRVVLPALQAALKKAGVTSPDSLMSRL 631
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  641 FGDSGRIDTQAVLRQQTALQLFMPIGHAILAGWESSDVDDPLAGLHATFGDLL--PQKPTRNVMNYLQQAIDHALPAgSD 718
Cdd:pfam07520 632 FGGDGQSVQDAVLRQQFTLQVFMPLALAILEAYERYDPLDPSAEIDATFADLLaaEEAPTAAVLEYVEEEVRRELPA-AT 710
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  719 AFDLFAVPLHVNFREMQDAMLAGQFTLASPLHAVCEAISHYSCDILLITGRPGCLPGVQALIRHLQPVPVNRIVWLDKYQ 798
Cdd:pfam07520 711 GFDLLDVPLSIDLEALHAIFLSNRMTITKTLRALCEVVHLYDCDVLLLTGRPSRLPGVRAIFRELLPLPPNRIIPLHNYR 790
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  799 VHEWYPFSQQGRIGNPKSTAAVGAMLCSLALDLRLPRFNFKAADIGAYSTVRYLGVLDNTvNTLREENVWYQDIDLDKPG 878
Cdd:pfam07520 791 TGDWYPFHKQGRIDDPKTTAAVGAMLCLLAEGLRLPNFYFRAGALRPYSTVRYIGELDSN-NQLKDDDVYYRDIDLDDPD 869
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  879 AKLDARLHFPLRGNVTLGFRQLANARWPATPLYTLSINSAELAKAIAGDGVLNVRLKLCGGSKQEG-PEAFELSDAWLQD 957
Cdd:pfam07520 870 YDLDPDATFEMRGPLRLGFRQLDNERWPATPLYTLDFANPKLARKLAGDGPLRVTLERDAGDDDAGvPEAFEIASAEDAD 949
                         970       980       990
                  ....*....|....*....|....*....|....
gi 495776716  958 GTPVAPDALTFKLNTLADrrhsGSHYWIDSGSVY 991
Cdd:pfam07520 950 GTTVPRDDLRLKLNTLGD----DDHYWLDTGSVF 979
 
Name Accession Description Interval E-value
SrfB COG4457
Virulence factor SrfB-related protein [Secondary metabolites biosynthesis, transport and ...
1-993 0e+00

Virulence factor SrfB-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443555  Cd Length: 998  Bit Score: 1769.45  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716   1 MLVNLCDYKQSVTLIANSGVQFLDFGLTPQ-DSASNGRFVRKTANGPLLRLDFDLVNGRYTLPGMNGGQPEVVKPETTIP 79
Cdd:COG4457    1 MLAELTDYKQEITLIPNSGIQFLDFGLDLDaRPELSGRFVRRSANGPLLRLLYDEESDKFLLPAPPGGAPEVVDPEYSIS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  80 LHQSLAVLDGVWLPVPFLRFNPPRTFVEGPDNWARVQVRKLDTPDTAGNTHRVTLALDSQIA--DHATSALSPVENDILN 157
Cdd:COG4457   81 LEQSLKLLDGVWLPLPFLRFNPPRRFDQGPDNWARVRIVELETPDDDGNTHRVTLAFDTKLVadDQNTAYLAPTEEDVRN 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 158 GTRFALAWRDNEVDSFLDQTWIDGWLREAFTQYADGVENRSERDLQQAMRSFEYQAHWLNLLTMLGEQLTVPEVKFVTHT 237
Cdd:COG4457  161 GASFALAWRNDEMAWFLDQTWVDGWLREVFKEFARERERRSEEDIEDALRQFEHQAHYLNLLSLLGSQLRVPEIKIVTTT 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 238 LS--TPAIPVDLILDVGNTHTCGVIIEDHGDANDGLRQTAELQVRSLSEPQFLNEPLFTSRLEFSEARFGKQHFSVESGR 315
Cdd:COG4457  241 LQdiVPAIPVDLVLDVGNSRTCGILIEDHPQENDGLKQSYELQLRDLSRPELVYNEPFESRVEFAQARFGKEHFSVESGR 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 316 EDAFVWPSIVRVGDEARKLAMQRLGTEGNSGISSPRRYLWDETPVVQDWRFSQMNSKTQREPLATAFPLMNLMNDDGEPL 395
Cdd:COG4457  321 RDAFVWPSIVRVGPEASRLAQRREGTEGSTGLSSPKRYLWDEDPYEQGWRFNQAYDKSDREPLATAAPLMRLINDRGEPL 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 396 FTLPQDERLPVFSPQYSRSTLMTHMLCELLAQALGQINSVATRLRLGFPASPRQLRTLILTLPSAMPKQEREIFRRRMFE 475
Cdd:COG4457  401 YQLPEDERLPVFSPHYSRSSLMTFMLSEVLAQALMQINSPAQRLRMGHSDAPRRLRSIILTLPSAMPKPEREIFRSRMEQ 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 476 AIAIVWKAMGWHPQDEDFVTRKQQEKSVVPVPEIQMEWDEASCGQLVWLYNEAISRFGGQTEAFFASLARPDREPEpGSQ 555
Cdd:COG4457  481 AIGLVWKSMGWHPGDDDFSTPEDKEKSWVPVPEVQVEWDEATCGQLVYLYNETQVNFGGRIEEFFASLARPDKQPD-GEA 559
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 556 PGRALRVASIDIGGGTTDMAITHYQLDDGSGNNVKITPQLLFREGFKVAGDDTLLDVIQRYVLPALQTQLQKSGIADASL 635
Cdd:COG4457  560 PGRTLRIASIDIGGGTTDLAITDYRLDDGVGSNVKITPEQLFREGFKVAGDDILLDVIQRYVLPALQAALKKAGVADAAS 639
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 636 LMASLFGDSGRIDTQAVLRQQTALQLFMPIGHAILAGWESSDVDDPLAGLHATFGDLLP-QKPTRNVMNYLQQAIdHALP 714
Cdd:COG4457  640 LLSRLFGGEGRSDQDAVLRQQLTLQVFMPLALAILSAYEQYDPLDRSAEISATFGELLElQPPTDKVLDYVNQAI-RREP 718
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 715 AGSDAFDLFAVPLHVNFREMQDAMLAGQFTLASPLHAVCEAISHYSCDILLITGRPGCLPGVQALIRHLQPVPVNRIVWL 794
Cdd:COG4457  719 AGAPPFDLLDVPLQIDLSDLHEAFLSGRMSICKPLRALCEVISHYDCDVLLLTGRPSRLPGVQALFRHLQPVPPNRILPL 798
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 795 DKYQVHEWYPFSQQGRIGNPKSTAAVGAMLCSLALDLRLPRFNFKAADIGAYSTVRYLGVLDNTvNTLREENVWYQDIDL 874
Cdd:COG4457  799 HGYRTGGWYPFHKNGRIDDPKSTAAVGAMLCLLSLDLRLPNFYFKAGDFQPYSTVRYLGLLDNN-NTLKDENVYYRDIDL 877
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716 875 DKPGAKLDARLHFPLRGNVTLGFRQLANARWPATPLYTLSINSAELAKAIAGDGVLNVRLKL--CGGSKQEGPEAFELSD 952
Cdd:COG4457  878 DDPDYTLDAEASFEMRGPVRLGFRQLDNERWPASPLYTLTINNPELARKIAGDGVLRVTLAVdkAKGRKEAGPERFEIAD 957
                        970       980       990      1000
                 ....*....|....*....|....*....|....*....|.
gi 495776716 953 AWLQDGTPVAPDALTFKLNTLADRRHSGSHYWIDSGSVYLK 993
Cdd:COG4457  958 AELSDGTPVPLRDLRLKLNTLADSGSGDSHYWLDSGSVYIK 998
SrfB pfam07520
Virulence factor SrfB; This family includes homologs of SsrAB is a two-component regulatory ...
8-991 0e+00

Virulence factor SrfB; This family includes homologs of SsrAB is a two-component regulatory system encoded within the Salmonella pathogenicity island SPI-2. Among the products of genes activated by SsrAB within epithelial and macrophage cells is Swiss:Q9KIJ9. homologs are found in several other proteobacteria.


Pssm-ID: 429510  Cd Length: 979  Bit Score: 1497.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716    8 YKQSVTLIANSGVQFLDFGLTPQ-DSASNGRFVRKTANGPLLRLDFDLVNGRYTLPGmnGGQPEVVKPET--TIPLHQSL 84
Cdd:pfam07520   1 YKQEVTLIPNSGIQFLDFGLTLDlRREPAGRFVRKSANGPLLRLSYDEERGRYFLPG--LAEPEVVRPEDeySVSLRQSL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716   85 AVLDGVWLPVPFLRFNPPRTFVEGPDNWARVQVRKLDTPDTAGNTHRVTLALDSQIAD--HATSALSPVENDILNGTRFA 162
Cdd:pfam07520  79 ELLDGVWLPLPFFRFNPPRRFDPGPTNWARVRIVALPTPDEDGNTHRVVLAFDTRVMAeeEGMAYLAPTPDDVKNGRSFR 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  163 LAWRDNEVDSFLDQTWIDGWLREAFTQYADGVENRSERDLQQamRSFEYQAHWLNLLTMLGEQLTVPEVKFVTHTLST-- 240
Cdd:pfam07520 159 LASRSEEMSWFLDQTWVDDWLREVFTEQAQQRLKRPRRDILP--REFEHQAHYLNLLDLLGAALALPEIKLVNNTADEiv 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  241 PAIPVDLILDVGNTHTCGVIIEDHGDANDGLRQTAELQVRSLSEPQFLNEPLFTSRLEFSEARFGKQHFSVESGREDAFV 320
Cdd:pfam07520 237 TPIDVDLVLDVGNSRTCGILIEDHPQESDGLKQSYELELRDLSRPEYLYSEPFESRVEFAQARFGKEHFSVRSGRDDAFV 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  321 WPSIVRVGDEARKLAMQRLGTEGNSGISSPRRYLWDETPVVQDWRFSQMNSKTQREPLATAFPLMNLMNDDGEPLFTLPQ 400
Cdd:pfam07520 317 WPSIVRVGPEAARLASLRRGTEGSTGLSSPKRYLWDEEAYEQGWRFNQAYVKGDQEPLATAAPLTRLINDLGEPLHQLPT 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  401 DERLPVFSPQYSRSTLMTHMLCELLAQALGQINSVATRLRLGFPASPRQLRTLILTLPSAMPKQEREIFRRRMFEAIAIV 480
Cdd:pfam07520 397 DERLPVFRPHYSRSSLMTFMLAEVLAQALMQINSPAQRLRRGHSDLPRRLRRIILTVPTAMPKPEREIFRQRAKQALALV 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  481 WKAMGWHPQDEDFVTRKQQEKSVVPVPEIQMEWDEASCGQLVWLYNEAISRFGGQTEAFFASLARPDREPEPGSqpgraL 560
Cdd:pfam07520 477 WKSLGWHPADDDFTPAKDKGKSWVPLPEVQMEWDEATCGQLVYLYNEVQQKFGGRAEEFFALLARPDKAGRPPS-----L 551
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  561 RVASIDIGGGTTDMAITHYQLDDGSGNNVKITPQLLFREGFKVAGDDTLLDVIQRYVLPALQTQLQKSGIADASLLMASL 640
Cdd:pfam07520 552 RVASIDIGGGTTDLVITDYRLDDGAGANVTITPEQRFRDGFKVAGDDILLDVIQRVVLPALQAALKKAGVTSPDSLMSRL 631
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  641 FGDSGRIDTQAVLRQQTALQLFMPIGHAILAGWESSDVDDPLAGLHATFGDLL--PQKPTRNVMNYLQQAIDHALPAgSD 718
Cdd:pfam07520 632 FGGDGQSVQDAVLRQQFTLQVFMPLALAILEAYERYDPLDPSAEIDATFADLLaaEEAPTAAVLEYVEEEVRRELPA-AT 710
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  719 AFDLFAVPLHVNFREMQDAMLAGQFTLASPLHAVCEAISHYSCDILLITGRPGCLPGVQALIRHLQPVPVNRIVWLDKYQ 798
Cdd:pfam07520 711 GFDLLDVPLSIDLEALHAIFLSNRMTITKTLRALCEVVHLYDCDVLLLTGRPSRLPGVRAIFRELLPLPPNRIIPLHNYR 790
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  799 VHEWYPFSQQGRIGNPKSTAAVGAMLCSLALDLRLPRFNFKAADIGAYSTVRYLGVLDNTvNTLREENVWYQDIDLDKPG 878
Cdd:pfam07520 791 TGDWYPFHKQGRIDDPKTTAAVGAMLCLLAEGLRLPNFYFRAGALRPYSTVRYIGELDSN-NQLKDDDVYYRDIDLDDPD 869
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495776716  879 AKLDARLHFPLRGNVTLGFRQLANARWPATPLYTLSINSAELAKAIAGDGVLNVRLKLCGGSKQEG-PEAFELSDAWLQD 957
Cdd:pfam07520 870 YDLDPDATFEMRGPLRLGFRQLDNERWPATPLYTLDFANPKLARKLAGDGPLRVTLERDAGDDDAGvPEAFEIASAEDAD 949
                         970       980       990
                  ....*....|....*....|....*....|....
gi 495776716  958 GTPVAPDALTFKLNTLADrrhsGSHYWIDSGSVY 991
Cdd:pfam07520 950 GTTVPRDDLRLKLNTLGD----DDHYWLDTGSVF 979
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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