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Conserved domains on  [gi|495777921|ref|WP_008502500|]
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MULTISPECIES: NAD(+) kinase [Enterobacteriaceae]

Protein Classification

NAD(+) kinase( domain architecture ID 10011922)

NAD(+) kinase catalyzes specifically the phosphorylation on the 2'-hydroxyl of the adenosine moiety of NAD to yield NADP, and is involved in regulating the intracellular balance of NAD and NADP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-292 0e+00

inorganic polyphosphate/ATP-NAD kinase; Provisional


:

Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 614.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   1 MNNHFRCIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAQELQLKSVKTGTLAEIGQQADLAVVVGGDGNMLGAA 80
Cdd:PRK03378   1 MNNHFKCIGIVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAIVVGGDGNMLGAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  81 RTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI 160
Cdd:PRK03378  81 RVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQKRISTAINEVVLHPGKVAHMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 161 EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSHRRNDL 240
Cdd:PRK03378 161 EFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSPNRSDL 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 495777921 241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGWSKKLF 292
Cdd:PRK03378 241 EISCDSQIALPIQPGEEVLIRRSDYHLNLIHPKDYSYFNTLRTKLGWSKKLF 292
 
Name Accession Description Interval E-value
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-292 0e+00

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 614.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   1 MNNHFRCIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAQELQLKSVKTGTLAEIGQQADLAVVVGGDGNMLGAA 80
Cdd:PRK03378   1 MNNHFKCIGIVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAIVVGGDGNMLGAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  81 RTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI 160
Cdd:PRK03378  81 RVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQKRISTAINEVVLHPGKVAHMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 161 EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSHRRNDL 240
Cdd:PRK03378 161 EFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSPNRSDL 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 495777921 241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGWSKKLF 292
Cdd:PRK03378 241 EISCDSQIALPIQPGEEVLIRRSDYHLNLIHPKDYSYFNTLRTKLGWSKKLF 292
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
5-290 1.02e-136

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 387.18  E-value: 1.02e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   5 FRCIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAqelqlksVKTGTLAEIGQQADLAVVVGGDGNMLGAARTLA 84
Cdd:COG0061    1 MKRIAIVAKPGKPEALEAAEELAELLEERGIEVVLDEDTA-------VPGVPLEELGEEADLVIVLGGDGTLLRAARLLA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  85 RYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEV 164
Cdd:COG0061   74 PLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDGEVVHEALALNEVVVLRGSIARMIELEV 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 165 YIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSHRRNDLEISC 244
Cdd:COG0061  154 YIDGEFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRPAVLVA 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 495777921 245 DSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGWSKK 290
Cdd:COG0061  234 DGQEVRDLEPGDRVEIRRSPKPVRLLRLKDHSFFERLREKLGWGGD 279
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 146-271 5.61e-53

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 169.02  E-value: 5.61e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  146 INEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVING 225
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 495777921  226 DSTIRLRFShRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIH 271
Cdd:pfam20143  81 SSKLRIRVL-SRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFIR 125
 
Name Accession Description Interval E-value
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-292 0e+00

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 614.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   1 MNNHFRCIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAQELQLKSVKTGTLAEIGQQADLAVVVGGDGNMLGAA 80
Cdd:PRK03378   1 MNNHFKCIGIVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAIVVGGDGNMLGAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  81 RTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI 160
Cdd:PRK03378  81 RVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQKRISTAINEVVLHPGKVAHMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 161 EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSHRRNDL 240
Cdd:PRK03378 161 EFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSPNRSDL 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 495777921 241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGWSKKLF 292
Cdd:PRK03378 241 EISCDSQIALPIQPGEEVLIRRSDYHLNLIHPKDYSYFNTLRTKLGWSKKLF 292
ppnK PRK02231
NAD(+) kinase;
22-291 7.79e-141

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 397.64  E-value: 7.79e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  22 THEMLYRWLCSKGYEVMVEQQIAQELQLKSVKTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFL 101
Cdd:PRK02231   1 MHKNLFHWLKERGYQVLVEKEIAEQLNLPENHLASLEEIGQRAQLAIVIGGDGNMLGRARVLAKYDIPLIGINRGNLGFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 102 TDLDPDNAQQQLADVLE-GHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLI 180
Cdd:PRK02231  81 TDIDPKNAYEQLEACLErGEFFVEERFLLEAKIERNGKIIATSNALNEVVIHPAKIAHMIDFHVYIDDKFAFSQRSDGLI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 181 ISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFS-HRRNDLEISCDSQIALPIQEGEDVL 259
Cdd:PRK02231 161 ISTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLSSRPLVIDGDSKISLRFAeYNTPQLEVSCDSQIALPFTPDDRVH 240

                        250       260       270
                 ....*....|....*....|....*....|..
gi 495777921 260 IRRCDYHLNLIHPKDYSYFNTLSSKLGWSKKL 291
Cdd:PRK02231 241 VQKSPDKLRLLHLKNYNYYNVLSSKLGWLKKL 272
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
5-290 1.02e-136

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 387.18  E-value: 1.02e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   5 FRCIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAqelqlksVKTGTLAEIGQQADLAVVVGGDGNMLGAARTLA 84
Cdd:COG0061    1 MKRIAIVAKPGKPEALEAAEELAELLEERGIEVVLDEDTA-------VPGVPLEELGEEADLVIVLGGDGTLLRAARLLA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  85 RYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEV 164
Cdd:COG0061   74 PLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDGEVVHEALALNEVVVLRGSIARMIELEV 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 165 YIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSHRRNDLEISC 244
Cdd:COG0061  154 YIDGEFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRPAVLVA 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 495777921 245 DSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGWSKK 290
Cdd:COG0061  234 DGQEVRDLEPGDRVEIRRSPKPVRLLRLKDHSFFERLREKLGWGGD 279
ppnK PRK01231
NAD(+) kinase;
2-291 3.14e-134

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 381.61  E-value: 3.14e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   2 NNHFRCIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAQELQLKSVKTGTLAEIGQQADLAVVVGGDGNMLGAAR 81
Cdd:PRK01231   1 MPSFRNIGLIGRLGSSSVVETLRRLKDFLLDRGLEVILDEETAEVLPGHGLQTVSRKLLGEVCDLVIVVGGDGSLLGAAR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  82 TLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIE 161
Cdd:PRK01231  81 ALARHNVPVLGINRGRLGFLTDIRPDELEFKLAEVLDGHYQEEERFLLEAEVRRGGEVIGQGDALNDVVLHPGKSTRMIE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 162 FEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFS-HRRNDL 240
Cdd:PRK01231 161 FELYIDGQFVCSQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAIVLVPMFPHTLSSRPIVVDGNSEIKIVISkDNRTYP 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 495777921 241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGWSKKL 291
Cdd:PRK01231 241 RVSCDGQNSVTLAPGDTVTIRKKPQKLRLIHPLDYNYYETCRTKLGWGSRL 291
ppnK PRK02155
NAD kinase;
1-288 4.22e-109

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 318.04  E-value: 4.22e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   1 MNNHFRCIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAQELQLKSVKTGTLAEIGQQADLAVVVGGDGNMLGAA 80
Cdd:PRK02155   1 MKSQFKTVALIGRYQTPGIAEPLESLAAFLAKRGFEVVFEADTARNIGLTGYPALTPEEIGARADLAVVLGGDGTMLGIG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  81 RTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI 160
Cdd:PRK02155  81 RQLAPYGVPLIGINHGRLGFITDIPLDDMQETLPPMLAGNYEEEERMLLEARVVRDGEPIFHALAFNDVVVNRSGFSGMV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 161 EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFsHRRNDL 240
Cdd:PRK02155 161 ELRVSVDGRFMYNQRSDGLIVATPTGSTAYALSAGGPILHPQLPGWVLVPIAPHTLSNRPIVLPDDSEVAIQI-VGGRDV 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 495777921 241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGWS 288
Cdd:PRK02155 240 SVNFDMQSLTSLELGDRIEVRRSPHTVRFLHPVGYSYYATLRKKLHWN 287
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-291 3.20e-82

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 249.77  E-value: 3.20e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   1 MNNHFRCIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAQELQLKSVKTGTL-----AEIGQQADLAVVVGGDGN 75
Cdd:PRK04539   1 MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYTQDTVGChivnkTELGQYCDLVAVLGGDGT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  76 MLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGK 155
Cdd:PRK04539  81 FLSVAREIAPRAVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERALALNDAVLSRGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 156 VAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSh 235
Cdd:PRK04539 161 AGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVT- 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 495777921 236 RRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGWSKKL 291
Cdd:PRK04539 240 QGGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHPTDYQYFKTLRQKLHWGEQL 295
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 8-287 6.20e-67

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 210.55  E-value: 6.20e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   8 IGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQ----IAQELQLKSVKTGTLAEIG--QQADLAVVVGGDGNMLGAAR 81
Cdd:PRK01911   3 IAIFGQTYQESASPYIQELFDELEERGAEVLIEEKfldfLKQDLKFHPSYDTFSDNEEldGSADMVISIGGDGTFLRTAT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  82 TLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQvCQQDCQKRISTAINEVVLHPGKVAHMIE 161
Cdd:PRK01911  83 YVGNSNIPILGINTGRLGFLATVSKEEIEETIDELLNGDYTIEERSLLQLE-SNPKLFGELNFALNEIAILKRDTSSMIT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 162 FEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSHRRNDLE 241
Cdd:PRK01911 162 VHTYLNGEYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPHNLNVRPLVIPDDTEITLEVESRSDNFL 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 495777921 242 ISCDSQIALpIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGW 287
Cdd:PRK01911 242 VSLDSRSET-VDNGTELTIKKADFTIKLVELNNHSFLKTLRNKLLW 286
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
29-286 8.66e-57

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 191.48  E-value: 8.66e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  29 WLCSKGYEVMVEQQIAQELQLKSVKTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDN 108
Cdd:PRK14076 314 YLDSKGIPYELESFLYNKLKNRLNEECNLIDDIEEISHIISIGGDGTVLRASKLVNGEEIPIICINMGTVGFLTEFSKEE 393

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 109 AQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGST 188
Cdd:PRK14076 394 IFKAIDSIISGEYEIEKRTKLSGFILKDGHQNILPSALNEVVITTKNPAKMLHFEVYVNGELVEEVRADGIIISTPTGST 473

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 189 AYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSHRRNDLEIscDSQIALPIQEGEDVLIRRCDYHLN 268
Cdd:PRK14076 474 AYSLSAGGPIVEPTVDGFIIVPICPFKLSSRPLVVSANSEIKIKLLKKSALVVI--DGSIEFEAKKGDEIIFRKSDSYAY 551

                        250
                 ....*....|....*...
gi 495777921 269 LIhpKDYSYFNTLSSKLG 286
Cdd:PRK14076 552 FV--KGDNFYNKLKKLSL 567
ppnK PRK02645
NAD(+) kinase;
57-287 9.74e-56

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 182.03  E-value: 9.74e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  57 LAEIGQQADLAVVVGGDGNMLGAARTLARYDIKVIGIN-RGNLGFLTDlDPDNAQ-QQLAD-VLEGHYISEKRFLLEAQV 133
Cdd:PRK02645  51 LASASELIDLAIVLGGDGTVLAAARHLAPHDIPILSVNvGGHLGFLTH-PRDLLQdESVWDrLQEDRYAIERRMMLQARV 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 134 CQQD---CQKRIST--AINEVVLHPGKVAHM----IEFEV---YIDEIfafsqRSDGLIISTPTGSTAYSLSAGGPILTP 201
Cdd:PRK02645 130 FEGDrsnEEPVSESyyALNDFYLKPASEDRSptciLELEIdgeVVDQY-----QGDGLIVSTPTGSTAYTMAAGGPILHP 204

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 202 SLDAITLVPMFPHTLSARPLVINGDSTIRLRfSHRRNDLEISC--DSQIALPIQEGEDVLIRRCDYH-LNLIHPKDYSYF 278
Cdd:PRK02645 205 GIDAIIVTPICPMSLSSRPIVIPPGSRVVIW-PLGDYDLNIKLwkDGVLATSIWPGQRCVIQKARHPaKFIILEESYSYY 283


                 ....*....
gi 495777921 279 NTLSSKLGW 287
Cdd:PRK02645 284 RTLREKLHW 292
ppnK PRK03708
NAD(+) kinase;
8-233 1.22e-55

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 181.06  E-value: 1.22e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   8 IGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAQEL-QLKSVKTGTLAEIgqQADLAVVVGGDGNMLgAARTLARY 86
Cdd:PRK03708   3 FGIVARRDKEEALKLAYRVYDFLKVSGYEVVVDSETYEHLpEFSEEDVLPLEEM--DVDFIIAIGGDGTIL-RIEHKTKK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  87 DIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDcqkrISTAINEVVLHPGKVAHMIEFEVYI 166
Cdd:PRK03708  80 DIPILGINMGTLGFLTEVEPEETFFALSRLLEGDYFIDERIKLRVYINGEN----VPDALNEVVILTGIPGKIIHLKYYV 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495777921 167 DEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRF 233
Cdd:PRK03708 156 DGELADEVRADGLIISTPTGSTAYAMSAGGPFVDPRLDAILIAPLCPFKLSSRPMVVPSSSRIDVKL 222
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 146-271 5.61e-53

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 169.02  E-value: 5.61e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  146 INEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVING 225
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 495777921  226 DSTIRLRFShRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIH 271
Cdd:pfam20143  81 SSKLRIRVL-SRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFIR 125
pnk PRK14077
NAD(+) kinase;
30-289 1.33e-51

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 171.12  E-value: 1.33e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  30 LCSKGYEVMVEQQIAQELQLKSVKTGTLAEIgqqADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNA 109
Cdd:PRK14077  34 LSIYKVEILLEKESAEILDLPGYGLDELFKI---SDFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLTDITVDEA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 110 QQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTA 189
Cdd:PRK14077 111 EKFFQAFFQGEFEIEKPYMLSVFLEKKQGKILEKLAFNDVVISKNNQASMAHIEAFLNEKYFNEYFGDGVIVATPAGSTA 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 190 YSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRfshRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNL 269
Cdd:PRK14077 191 YNMSANGPIIYPLSQVFILTPVCSHSLTQRPIVLPKGFEVEFK---TKSDCILCIDGQDRYKMNDFKSIKVGLSDKNVAL 267

                        250       260
                 ....*....|....*....|
gi 495777921 270 IHPKDYSYFNTLSSKLGWSK 289
Cdd:PRK14077 268 IRHKNRDYFQILKEKLHWGN 287
ppnK PRK02649
NAD(+) kinase;
7-287 6.77e-51

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 169.77  E-value: 6.77e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   7 CIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIA---------QELQLKSVKTGTLAEIGQQADLAVVVGGDGNML 77
Cdd:PRK02649   3 KAGIIYNDGKPLAVRTAEELQDKLEAAGWEVVRASSSGgilgyanpdQPVCHTGIDQLVPPGFDSSMKFAIVLGGDGTVL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  78 GAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVA 157
Cdd:PRK02649  83 SAARQLAPCGIPLLTINTGHLGFLTEAYLNQLDEAIDQVLAGQYTIEERTMLTVSVMRGDQLRWEALSLNEMVLHREPLT 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 158 HMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLrFSHRR 237
Cdd:PRK02649 163 SMCHFEIAIGRHAPVDIAADGVILSTPTGSTAYSLSAGGPVITPDVPVLQLTPICPHSLASRALVFSDSEPVTV-FPATP 241

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 495777921 238 NDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSSKLGW 287
Cdd:PRK02649 242 ERLVMVVDGNAGCYVWPEDRVLIRRSPYPVRFIRLQDPEFFRVLREKLGW 291
pnk PRK14075
NAD(+) kinase;
39-291 8.82e-43

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 147.18  E-value: 8.82e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  39 VEQQIAQELQLKSVkTGTLAEIGQQADLAVVVGGDGNMLGAARtlaRYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLE 118
Cdd:PRK14075  18 LKEKISKEHEVVEF-CEASASGKVTADLIIVVGGDGTVLKAAK---KVGTPLVGFKAGRLGFLSSYTLEEIDRFLEDLKN 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 119 GHYISEKRFLLEAQVCQQDcqkriSTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPI 198
Cdd:PRK14075  94 WNFREEKRWFLKIESELGN-----HLALNDVTLERDPSQKMVEIEVSFEDHSSMWFFADGVVISTPTGSTAYSLSLGGPI 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 199 LTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFShrrNDLEISCDSQIALPIQEgedVLIRRCDYHLNLIHPKDYSYF 278
Cdd:PRK14075 169 ILPNCEVFEITPIAPQFLATRSIVIPSNEKVTVESQ---RDINLIVDGVLVGKTNR---ITVKKSRRYVRILRPKDYDFV 242

                        250
                 ....*....|...
gi 495777921 279 NTLSSKLGWSKKL 291
Cdd:PRK14075 243 TVIKEKLGYGRRI 255
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 6-264 4.19e-42

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 146.99  E-value: 4.19e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921   6 RCIGIVGHPRHPTALTTHEMLYRWLCSKGYEVMVEQQIAQELQLKSVKTGTLAEIG---------QQADLAVVVGGDGNM 76
Cdd:PRK03372   6 RRVLLVAHTGRDEATEAARRVAKQLGDAGIGVRVLDAEAVDLGATHPAPDDFRAMEvvdadpdaaDGCELVLVLGGDGTI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  77 LGAARtLAR-YDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVcQQDCQKRIST-AINEVVLHPG 154
Cdd:PRK03372  86 LRAAE-LARaADVPVLGVNLGHVGFLAEAEAEDLDEAVERVVDRDYRVEERMTLDVTV-RVGGEIVWRGwALNEASLEKA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 155 KVAHMIEFEVYIDE--IFAFSqrSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLR 232
Cdd:PRK03372 164 DREGMLEVVLEVDGrpVSSFG--CDGVLVSTPTGSTAYAFSAGGPVVWPDLEALLVVPLNAHALFARPLVVSPTSTVAVE 241

                        250       260       270
                 ....*....|....*....|....*....|....
gi 495777921 233 FSHRRNDLEISCDS--QIALPiqEGEDVLIRRCD 264
Cdd:PRK03372 242 ILADTSDAVLWCDGrrSVDLP--PGARVEVRRGA 273
ppnK PRK01185
NAD(+) kinase;
33-262 4.26e-42

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 145.73  E-value: 4.26e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  33 KGYEVMVEQQIAQELQLKSVktgTLAEIgqQADLAVVVGGDGNMLgaaRTLARYDIKVIGINRGNLGFLTDLDPDNAQQQ 112
Cdd:PRK01185  27 PDWEIIYEMEAAKALGMDGL---DIEEI--NADVIITIGGDGTIL---RTLQRAKGPILGINMGGLGFLTEIEIDEVGSA 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 113 LADVLEGHYISEKRFLLEAQVCQQdcqkRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSL 192
Cdd:PRK01185  99 IKKLIRGEYFIDERMKLKVYINGE----RLEDCTNEAVIHTDRIAKIRQFKIYYDGHFLDTFKADGVIVATPTGSTSYSS 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 193 SAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSHRRNDLEIsCDSQIALPIQEGEDVLIRR 262
Cdd:PRK01185 175 SAGGPILLPNLEGMVISYIAPYSSRPKSVVVPSESTVEIKIAGDQSSLLI-LDGQYEYKISKGDTVEISK 243
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 8-118 5.44e-33

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 117.85  E-value: 5.44e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921    8 IGIVGHPRHPTALTTHEMLYRWLC-SKGYEVMVEQQIAQELQLKS----------------VKTGTLAEIGQQADLAVVV 70
Cdd:pfam01513   1 VGIVVNPDKKEALERAREVARWLLdRLGITVTVEEKMGESLAFAAgdrpevigclkkvvddTRRATRAFADAGVDLIIVL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 495777921   71 GGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLE 118
Cdd:pfam01513  81 GGDGTALRAARLLQKAVIPILGVNTGVLGFLTEFEPEAAFELLERLLE 128
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 24-235 1.40e-30

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 119.94  E-value: 1.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  24 EMLyRWL-CSKGYEVMVEQQIAQELQLKS-----VKT----GTLAEIGQQADLAVVVGGDGNMLGAARTLARYDIKVIGI 93
Cdd:PLN02935 214 EMV-RWLrEQKGLNIYVEPRVKKELLSESsyfnfVQTwedeKEILLLHTKVDLVITLGGDGTVLWAASMFKGPVPPVVPF 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  94 NRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRIST-----AINEVVLHPGKVAHMIEFEVYIDE 168
Cdd:PLN02935 293 SMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHIIRDAAKNEYETeepilVLNEVTIDRGISSFLTNLECYCDN 372

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495777921 169 IFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINGDSTIRLRFSH 235
Cdd:PLN02935 373 SFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEYVTIRVQVPF 439
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 41-247 5.96e-25

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 100.28  E-value: 5.96e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  41 QQIAQELQLKSVKTG-TLAEigQQADLAVVVGGDGNMLGAartLARY-----DIKVIGINRGNLGFLTDLDPDNAQQQLA 114
Cdd:PRK04885  14 KRVASKLKKYLKDFGfILDE--KNPDIVISVGGDGTLLSA---FHRYenqldKVRFVGVHTGHLGFYTDWRPFEVDKLVI 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 115 DVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHpgKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSA 194
Cdd:PRK04885  89 ALAKDPGQVVSYPLLEVKITYEDGEKEKYLALNEATIK--RIEGTLVADVYINGVLFERFRGDGLCVSTPTGSTAYNKSL 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 195 GGPILTPSLDAITLVPM-------FpHTLSArPLVINGDSTIRLRfSHRRNDLEISCDSQ 247
Cdd:PRK04885 167 GGAVLHPSIEALQLTEIasinnrvF-RTLGS-PLILPKHHTITLK-PVNDDDYQITVDHL 223
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 63-199 4.03e-24

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 97.58  E-value: 4.03e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  63 QADLAVVVGGDGNMLgaaRTLARY---DIKVIGINRGNLGFL-TDLDPDNAQQQLAdvlegHYISEKRFLLEAQVCQQDC 138
Cdd:PRK04761  25 EADVIVALGGDGFML---QTLHRYmnsGKPVYGMNRGSVGFLmNEYSEDDLLERIA-----AAEPTVLHPLRMTATDVSG 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 495777921 139 QKRISTAINEVVL----HpgKVAHMiefEVYIDEIFAFSQ-RSDGLIISTPTGSTAYSLSAGGPIL 199
Cdd:PRK04761  97 EVHEALAINEVSLfrqtR--QAAKL---RISIDGKVRMEElVCDGVLVATPAGSTAYNLSAHGPIL 157
ppnK PRK03501
NAD kinase;
62-279 4.49e-21

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 90.04  E-value: 4.49e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  62 QQADLAVVVGGDGNMLGAAR-TLARYDIKVIGINR-GNLGFLTDLDPDNaQQQLADVLEGHYISEKRF-LLEAQV----- 133
Cdd:PRK03501  38 KNANIIVSIGGDGTFLQAVRkTGFREDCLYAGISTkDQLGFYCDFHIDD-LDKMIQAITKEEIEVRKYpTIEVTVdgsts 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 134 --CQQDCQKRiSTAINEVVLhpgkvahmiefEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPsldaitLVPM 211
Cdd:PRK03501 117 fyCLNEFSIR-SSIIKTFVI-----------DVYIDDLHFETFRGDGMVVSTPTGSTAYNKSVRGAVVDP------LIPC 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 212 FP------------HTLSArPLVINGDSTIRLRFSHRRNDLE-ISCDSQiALPIQEGEDVLIRRCDYHLNLIHPKDYSYF 278
Cdd:PRK03501 179 FQvselaslnnntyRTLGS-PFILSHERKLTLKIVQDGNDYPiIGMDNE-ALSIKHVEKIDIRLSDKQIKTVKLKDNSFW 256


                 .
gi 495777921 279 N 279
Cdd:PRK03501 257 E 257
PLN02727 PLN02727
NAD kinase
 62-291 1.10e-19

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 89.18  E-value: 1.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  62 QQADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADV------LEGHYISeKRFLLEAQVCQ 135
Cdd:PLN02727 742 ERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVihgnntLDGVYIT-LRMRLRCEIFR 820

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 136 --QDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFP 213
Cdd:PLN02727 821 ngKAMPGKVFDVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPICP 900

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 214 HTLSARPLVINGDSTIRLRF-SHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS--YFNTLSSKLGWSKK 290
Cdd:PLN02727 901 HSLSFRPVILPDSARLELKIpDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPTVNKSDQTgdWFRSLIRCLNWNER 980


                 .
gi 495777921 291 L 291
Cdd:PLN02727 981 L 981
ppnK PRK00561
NAD(+) kinase;
49-232 1.15e-18

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 83.39  E-value: 1.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  49 LKSVKTGTLAEIgQQADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEG-HYisEKRF 127
Cdd:PRK00561  20 LKKVLKKKLAVE-DGADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGFYTSFNETDLDQNFANKLDQlKF--TQID 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 128 LLEAQVCQQdcqkrISTAINEVVLHPgKVAHMIEfeVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAIT 207
Cdd:PRK00561  97 LLEVQIDDQ-----IHLVLNELAVYT-NTAYPIN--IFIDNEFWEKYRGSGLLIGPRTGSTALAKSAKGAVIFPRIDVIQ 168

                        170       180       190
                 ....*....|....*....|....*....|
gi 495777921 208 LVPMFP-----HTLSARPLVINGDSTIRLR 232
Cdd:PRK00561 169 IIELNPllhpnQTTIQSPIILPIDTKVEFE 198
PLN02929 PLN02929
NADH kinase
 64-276 9.63e-12

NADH kinase


Pssm-ID: 215502 [Multi-domain]  Cd Length: 301  Bit Score: 64.29  E-value: 9.63e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921  64 ADLAVVVGGDGNMLGAARTLaRYDIKVIGIN------------------RGNLGFLTDLDPDNAQQQLADVLEGhyiseK 125
Cdd:PLN02929  65 VDLVVAVGGDGTLLQASHFL-DDSIPVLGVNsdptqkdeveeysdefdaRRSTGHLCAATAEDFEQVLDDVLFG-----R 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 126 RFLLEAQvcqqdcqkRISTAINEVVL-----------HPgKVAHMIEFEVYI-----DEIFAFSQRSDGLIISTPTGSTA 189
Cdd:PLN02929 139 LKPTELS--------RISTVVNGTLLetpalndvliaHP-SPAAVSRFSFRVgrqggSSGPLINVRSSGLRVSTAAGSTA 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495777921 190 YSLSAGG---PILTPSLDAITLVPMFPHtlSARPLVING----DSTIRLRFSHRRNDLEIScDSQIALPIQEGEDVLIRR 262
Cdd:PLN02929 210 AMLSAGGfpmPLLSRDLQYMVREPISPG--HPPKSLMHGfykpGQHMQVRWNSRKGTIYID-GSHVMHSIKLGDTIEISS 286

                        250
                 ....*....|....
gi 495777921 263 CDYHLNLIHPKDYS 276
Cdd:PLN02929 287 DAPPLKVFLSHWFL 300
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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