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Conserved domains on  [gi|495778694|ref|WP_008503273|]
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MULTISPECIES: shikimate kinase AroL [Enterobacteriaceae]

Protein Classification

shikimate kinase( domain architecture ID 10792322)

shikimate kinase catalyzes the specific phosphorylation of the 3-hydroxylgroup of shikimic acid using ATP as a cosubstrate

EC:  2.7.1.71

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
aroL PRK03731
shikimate kinase AroL;
1-171 2.74e-107

shikimate kinase AroL;


:

Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 303.79  E-value: 2.74e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   1 MTQPIFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTTPSAVIATGGG 80
Cdd:PRK03731   1 MTQPLFLVGARGCGKTTVGMALAQALGYRFVDTDQWLQSTSNMTVAEIVEREGWAGFRARESAALEAVTAPSTVIATGGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  81 IVLAECNRHFMREKGIVIYLSAPVSALVGRLEAFPEEGQRPALTSRPLNEEVSEVLAERDALYREAAHHVVDASASPEDV 160
Cdd:PRK03731  81 IILTEENRHFMRNNGIVIYLCAPVSVLANRLEANPEEDQRPTLTGKPISEEVAEVLAEREALYREVAHHIIDATQPPSQV 160

                        170
                 ....*....|.
gi 495778694 161 VIQIITALRLA 171
Cdd:PRK03731 161 VSEILSALAQS 171
 
Name Accession Description Interval E-value
aroL PRK03731
shikimate kinase AroL;
1-171 2.74e-107

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 303.79  E-value: 2.74e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   1 MTQPIFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTTPSAVIATGGG 80
Cdd:PRK03731   1 MTQPLFLVGARGCGKTTVGMALAQALGYRFVDTDQWLQSTSNMTVAEIVEREGWAGFRARESAALEAVTAPSTVIATGGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  81 IVLAECNRHFMREKGIVIYLSAPVSALVGRLEAFPEEGQRPALTSRPLNEEVSEVLAERDALYREAAHHVVDASASPEDV 160
Cdd:PRK03731  81 IILTEENRHFMRNNGIVIYLCAPVSVLANRLEANPEEDQRPTLTGKPISEEVAEVLAEREALYREVAHHIIDATQPPSQV 160

                        170
                 ....*....|.
gi 495778694 161 VIQIITALRLA 171
Cdd:PRK03731 161 VSEILSALAQS 171
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 5-169 1.14e-64

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 195.73  E-value: 1.14e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVT-TPSAVIATGGGIVL 83
Cdd:COG0703    1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLeEENAVIATGGGAVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  84 AECNRHFMREKGIVIYLSAPVSALVGRLEAfpeEGQRPALTSRPLNEEVSEVLAERDALYREAAHHVVDASA-SPEDVVI 162
Cdd:COG0703   81 SPENRELLKEHGTVVYLDASPETLLERLRR---DDNRPLLQGEDPRERLEELLAEREPLYREVADITVDTDGrSPEEVVD 157


                 ....*..
gi 495778694 163 QIITALR 169
Cdd:COG0703  158 EILEALE 164
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 4-159 3.60e-53

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 166.19  E-value: 3.60e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   4 PIFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTTP-SAVIATGGGIV 82
Cdd:cd00464    1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELEREVLLLLLTKeNAVIATGGGAV 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495778694  83 LAECNRHFMREKGIVIYLSAPVSALVGRLEAfpeEGQRPALtSRPLNEEVSEVLAERDALYREAAHHVVDASASPED 159
Cdd:cd00464   81 LREENRRLLLENGIVVWLDASPEELLERLAR---DKTRPLL-QDEDPERLRELLEEREPLYREVADLTIDTDELSPE 153
SKI pfam01202
Shikimate kinase;
11-169 1.15e-52

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 165.06  E-value: 1.15e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   11 RGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTT-PSAVIATGGGIVLAECNRH 89
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAeHGLVIATGGGAVLSEENRD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   90 FMREKGIVIYLSAPVSALVGRLEAfpeEGQRPALTSRPLNEEVSEVLA-ERDALYREAAHHVVDAS-ASPEDVVIQIITA 167
Cdd:pfam01202  81 LLKERGIVIYLDAPLEVLLERLKR---DKTRPLLQNKDPEEELLELLFeERDPLYEEAADIVIDTDeSSPEEVATEILEA 157


                  ..
gi 495778694  168 LR 169
Cdd:pfam01202 158 LE 159
 
Name Accession Description Interval E-value
aroL PRK03731
shikimate kinase AroL;
1-171 2.74e-107

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 303.79  E-value: 2.74e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   1 MTQPIFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTTPSAVIATGGG 80
Cdd:PRK03731   1 MTQPLFLVGARGCGKTTVGMALAQALGYRFVDTDQWLQSTSNMTVAEIVEREGWAGFRARESAALEAVTAPSTVIATGGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  81 IVLAECNRHFMREKGIVIYLSAPVSALVGRLEAFPEEGQRPALTSRPLNEEVSEVLAERDALYREAAHHVVDASASPEDV 160
Cdd:PRK03731  81 IILTEENRHFMRNNGIVIYLCAPVSVLANRLEANPEEDQRPTLTGKPISEEVAEVLAEREALYREVAHHIIDATQPPSQV 160

                        170
                 ....*....|.
gi 495778694 161 VIQIITALRLA 171
Cdd:PRK03731 161 VSEILSALAQS 171
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 5-169 1.14e-64

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 195.73  E-value: 1.14e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVT-TPSAVIATGGGIVL 83
Cdd:COG0703    1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLeEENAVIATGGGAVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  84 AECNRHFMREKGIVIYLSAPVSALVGRLEAfpeEGQRPALTSRPLNEEVSEVLAERDALYREAAHHVVDASA-SPEDVVI 162
Cdd:COG0703   81 SPENRELLKEHGTVVYLDASPETLLERLRR---DDNRPLLQGEDPRERLEELLAEREPLYREVADITVDTDGrSPEEVVD 157


                 ....*..
gi 495778694 163 QIITALR 169
Cdd:COG0703  158 EILEALE 164
aroK PRK00131
shikimate kinase; Reviewed
 5-171 1.68e-53

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 167.67  E-value: 1.68e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVT-TPSAVIATGGGIVL 83
Cdd:PRK00131   7 IVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARAGKSIPEIFEEEGEAAFRELEEEVLAELLaRHNLVISTGGGAVL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  84 AECNRHFMREKGIVIYLSAPVSALVGRLEafpeegqrpALTSRPL------NEEVSEVLAERDALYREAAHHVVD-ASAS 156
Cdd:PRK00131  87 REENRALLRERGTVVYLDASFEELLRRLR---------RDRNRPLlqtndpKEKLRDLYEERDPLYEEVADITVEtDGRS 157

                        170
                 ....*....|....*
gi 495778694 157 PEDVVIQIITALRLA 171
Cdd:PRK00131 158 PEEVVNEILEKLEAA 172
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 4-159 3.60e-53

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 166.19  E-value: 3.60e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   4 PIFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTTP-SAVIATGGGIV 82
Cdd:cd00464    1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELEREVLLLLLTKeNAVIATGGGAV 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495778694  83 LAECNRHFMREKGIVIYLSAPVSALVGRLEAfpeEGQRPALtSRPLNEEVSEVLAERDALYREAAHHVVDASASPED 159
Cdd:cd00464   81 LREENRRLLLENGIVVWLDASPEELLERLAR---DKTRPLL-QDEDPERLRELLEEREPLYREVADLTIDTDELSPE 153
SKI pfam01202
Shikimate kinase;
11-169 1.15e-52

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 165.06  E-value: 1.15e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   11 RGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTT-PSAVIATGGGIVLAECNRH 89
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAeHGLVIATGGGAVLSEENRD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   90 FMREKGIVIYLSAPVSALVGRLEAfpeEGQRPALTSRPLNEEVSEVLA-ERDALYREAAHHVVDAS-ASPEDVVIQIITA 167
Cdd:pfam01202  81 LLKERGIVIYLDAPLEVLLERLKR---DKTRPLLQNKDPEEELLELLFeERDPLYEEAADIVIDTDeSSPEEVATEILEA 157


                  ..
gi 495778694  168 LR 169
Cdd:pfam01202 158 LE 159
PRK13947 PRK13947
shikimate kinase; Provisional
 5-167 2.55e-32

shikimate kinase; Provisional


Pssm-ID: 184412 [Multi-domain]  Cd Length: 171  Bit Score: 113.65  E-value: 2.55e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTTP-SAVIATGGGIVL 83
Cdd:PRK13947   4 IVLIGFMGTGKTTVGKRVATTLSFGFIDTDKEIEKMTGMTVAEIFEKDGEVRFRSEEKLLVKKLARLkNLVIATGGGVVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  84 AECNRHFMREKGIVIYLSAPVSALVGRLEafpEEGQRPALTSRPLNEEVSEVLAERDALYREAAHHVVDASASPEDVVIQ 163
Cdd:PRK13947  84 NPENVVQLRKNGVVICLKARPEVILRRVG---KKKSRPLLMVGDPEERIKELLKEREPFYDFADYTIDTGDMTIDEVAEE 160


                 ....
gi 495778694 164 IITA 167
Cdd:PRK13947 161 IIKA 164
aroK PRK05057
shikimate kinase AroK;
5-168 1.46e-31

shikimate kinase AroK;


Pssm-ID: 235335 [Multi-domain]  Cd Length: 172  Bit Score: 111.73  E-value: 1.46e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTTPSA-VIATGGGIVL 83
Cdd:PRK05057   7 IFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADIGWVFDVEGEEGFRDREEKVINELTEKQGiVLATGGGSVK 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  84 AECNRHFMREKGIVIYLSAPVSALVGRLEafpEEGQRPAL-TSRPlnEEVSEVLA-ERDALYREAAHHVVDAS-ASPEDV 160
Cdd:PRK05057  87 SRETRNRLSARGVVVYLETTIEKQLARTQ---RDKKRPLLqVDDP--REVLEALAnERNPLYEEIADVTIRTDdQSAKVV 161


                 ....*...
gi 495778694 161 VIQIITAL 168
Cdd:PRK05057 162 ANQIIHML 169
PRK13949 PRK13949
shikimate kinase; Provisional
 4-168 5.97e-26

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 97.11  E-value: 5.97e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   4 PIFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTT-PSAVIATGGGiv 82
Cdd:PRK13949   3 RIFLVGYMGAGKTTLGKALARELGLSFIDLDFFIENRFHKTVGDIFAERGEAVFRELERNMLHEVAEfEDVVISTGGG-- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  83 lAEC---NRHFMREKGIVIYLSAPVSALVGRLEAFPEegQRPALTSRP---LNEEVSEVLAERDALYREAAHHVVDASAS 156
Cdd:PRK13949  81 -APCffdNMELMNASGTTVYLKVSPEVLFVRLRLAKQ--QRPLLKGKSdeeLLDFIIEALEKRAPFYRQAKIIFNADKLE 157

                        170
                 ....*....|..
gi 495778694 157 PEDVVIQIITAL 168
Cdd:PRK13949 158 DESQIEQLVQRL 169
PRK13948 PRK13948
shikimate kinase; Provisional
 7-168 9.77e-25

shikimate kinase; Provisional


Pssm-ID: 184413 [Multi-domain]  Cd Length: 182  Bit Score: 94.47  E-value: 9.77e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   7 LVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAVTTPS-AVIATGGGIVLAE 85
Cdd:PRK13948  15 LAGFMGTGKSRIGWELSRALMLHFIDTDRYIERVTGKSIPEIFRHLGEAYFRRCEAEVVRRLTRLDyAVISLGGGTFMHE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  86 CNRHFMREKGIVIYLSAPVSALVGRLeafpEEGQRPALTSRPLNEEVSEVLAERDALYREAAHHVVDASASPEDVVIQII 165
Cdd:PRK13948  95 ENRRKLLSRGPVVVLWASPETIYERT----RPGDRPLLQVEDPLGRIRTLLNEREPVYRQATIHVSTDGRRSEEVVEEIV 170


                 ...
gi 495778694 166 TAL 168
Cdd:PRK13948 171 EKL 173
PRK13946 PRK13946
shikimate kinase; Provisional
 2-169 5.06e-24

shikimate kinase; Provisional


Pssm-ID: 184411 [Multi-domain]  Cd Length: 184  Bit Score: 92.68  E-value: 5.06e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   2 TQPIFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKA-VTTPSAVIATGGG 80
Cdd:PRK13946  10 KRTVVLVGLMGAGKSTVGRRLATMLGLPFLDADTEIERAARMTIAEIFAAYGEPEFRDLERRVIARlLKGGPLVLATGGG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  81 IVLAECNRHFMREKGIVIYLSAPVSALVGRLEAFPEegqRPALTSRPLNEEVSEVLAERDALYREAAHHVVDASASPEDV 160
Cdd:PRK13946  90 AFMNEETRAAIAEKGISVWLKADLDVLWERVSRRDT---RPLLRTADPKETLARLMEERYPVYAEADLTVASRDVPKEVM 166


                 ....*....
gi 495778694 161 VIQIITALR 169
Cdd:PRK13946 167 ADEVIEALA 175
PRK13951 PRK13951
bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;
5-145 1.82e-19

bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;


Pssm-ID: 172457 [Multi-domain]  Cd Length: 488  Bit Score: 84.57  E-value: 1.82e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAAL-KAVTTPSAVIATGGGIVL 83
Cdd:PRK13951   3 IFLVGMMGSGKSTIGKRVSEVLDLQFIDMDEEIERREGRSVRRIFEEDGEEYFRLKEKELLrELVERDNVVVATGGGVVI 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 495778694  84 AECNRHFMReKGIVIYLSAPVSALVGRLeafpeegqrpALTSRPL----NEEVSEVLAERDALYRE 145
Cdd:PRK13951  83 DPENRELLK-KEKTLFLYAPPEVLMERV----------TTENRPLlregKERIREIWERRKQFYTE 137
PLN02199 PLN02199
shikimate kinase
 5-123 2.07e-19

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 82.82  E-value: 2.07e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWL-QTEAGKTIADIVEQEGWESFRARETAALKAVTTP-SAVIATGGGIV 82
Cdd:PLN02199 105 MYLVGMMGSGKTTVGKLMSKVLGYTFFDCDTLIeQAMNGTSVAEIFVHHGENFFRGKETDALKKLSSRyQVVVSTGGGAV 184

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 495778694  83 LAECNRHFMrEKGIVIYLSAPVSALVGRLEAFpEEGQRPAL 123
Cdd:PLN02199 185 IRPINWKYM-HKGISIWLDVPLEALAHRIAAV-GTDSRPLL 223
PRK00625 PRK00625
shikimate kinase; Provisional
 5-149 2.57e-12

shikimate kinase; Provisional


Pssm-ID: 134335 [Multi-domain]  Cd Length: 173  Bit Score: 61.70  E-value: 2.57e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIAD----IVEQEGWESFRARETAALKAVTTPSAVIATGGG 80
Cdd:PRK00625   3 IFLCGLPTVGKTSFGKALAKFLSLPFFDTDDLIVSNYHGALYSspkeIYQAYGEEGFCREEFLALTSLPVIPSIVALGGG 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495778694  81 IVLAECNRHFMREKGIVIYLSAPVSALVGRLE--AFPEEGQRPAltsrplneEVSEVLAER-DALYREAAHH 149
Cdd:PRK00625  83 TLMIEPSYAHIRNRGLLVLLSLPIATIYQRLQkrGLPERLKHAP--------SLEEILSQRiDRMRSIADYI 146
PRK14021 PRK14021
bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional
 1-158 4.68e-11

bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional


Pssm-ID: 184458 [Multi-domain]  Cd Length: 542  Bit Score: 60.26  E-value: 4.68e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   1 MTQPI-FLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARET-AALKAVTTPSAVIATG 78
Cdd:PRK14021   4 TRRPQaVIIGMMGAGKTRVGKEVAQMMRLPFADADVEIEREIGMSIPSYFEEYGEPAFREVEAdVVADMLEDFDGIFSLG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  79 GGIVLAECNRH----FMREKGIVIYLSA-PVSAlvgrLEAFPEEGQRPALTSRPlNEEVSEVLAERDALYREAAH-HVVD 152
Cdd:PRK14021  84 GGAPMTPSTQHalasYIAHGGRVVYLDAdPKEA----MERANRGGGRPMLNGDA-NKRWKKLFKQRDPVFRQVANvHVHT 158


                 ....*.
gi 495778694 153 ASASPE 158
Cdd:PRK14021 159 RGLTPQ 164
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 5-173 2.90e-09

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 54.57  E-value: 2.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGKTIADIVEQEGWESFRARETAALKAV--TTPSAVIATGGGIV 82
Cdd:PRK08154 136 IALIGLRGAGKSTLGRMLAARLGVPFVELNREIEREAGLSVSEIFALYGQEGYRRLERRALERLiaEHEEMVLATGGGIV 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  83 ---------LAECnrhfmrekgIVIYLSAPvsalvgrleafPEE------GQ---RPALTSRPLNEEVSEVLAERDALYr 144
Cdd:PRK08154 216 sepatfdllLSHC---------YTVWLKAS-----------PEEhmarvrAQgdlRPMADNREAMEDLRRILASREPLY- 274

                        170       180       190
                 ....*....|....*....|....*....|
gi 495778694 145 EAAHHVVDASA-SPEDVVIQIITALRLACA 173
Cdd:PRK08154 275 ARADAVVDTSGlTVAQSLARLRELVRPALG 304
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 2-169 5.09e-05

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 41.65  E-value: 5.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   2 TQPIFLVGPRGCGKTTVGLELARVCHRQFVDTD--H---------------------WLQteagkTIADIVEqegwesfr 58
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDdfHppaniakmaagipltdedrapWLE-----ALADAIA-------- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  59 aretaalkavttpsAVIATGGGIVLA-----ECNRHFMREKG---IVIYLSAPVSALVGRLEA-----FPEE---GQRPA 122
Cdd:COG3265   68 --------------AHLAAGEGAVLAcsalkRSYRDRLREGNpdvRFVYLDGSRELIAERLAArkghfMPASlldSQFAT 133

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 495778694 123 LtsrplneevsEVLAErdalyrEAAHHVVDASASPEDVVIQIITALR 169
Cdd:COG3265  134 L----------EPPGP------DEDAIVVDIDQPPEEIVAQILAALG 164
AAA_18 pfam13238
AAA domain;
5-137 4.42e-04

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 38.18  E-value: 4.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694    5 IFLVGPRGCGKTTVGLELARvcHRQFVDTDHWLQTEAGktIADIVEQEGWESFRARETAALKAVTT--PSAVIATGGGIV 82
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSK--RLGFGDNVRDLALENG--LVLGDDPETRESKRLDEDKLDRLLDLleENAALEEGGNLI 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 495778694   83 LAECNRHF---MREKGIVIYLSAPVSALVGRLEAfpeegqRPALTSRPLNEEVSEVLA 137
Cdd:pfam13238  77 IDGHLAELepeRAKDLVGIVLRASPEELLERLEK------RGYEEAKIKENEEAEILG 128
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
5-160 2.53e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 36.81  E-value: 2.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTDHWLQTEAGktiADIVEQEGWESFRARETAALKAVTTpsAVIATGGGIVL- 83
Cdd:COG0645    2 ILVCGLPGSGKSTLARALAERLGAVRLRSDVVRKRLFG---AGLAPLERSPEATARTYARLLALAR--ELLAAGRSVILd 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778694  84 AECNRHFMREKGI-----------VIYLSAPVSALVGRLEAFPEEGQRPALTSrplnEEVSEVLAERDAL-YREAAHHVV 151
Cdd:COG0645   77 ATFLRRAQREAFRalaeeagapfvLIWLDAPEEVLRERLEARNAEGGDSDATW----EVLERQLAFEEPLtEDEGFLLVV 152


                 ....*....
gi 495778694 152 DASASPEDV 160
Cdd:COG0645  153 DTSGLEEAL 161
AAA_24 pfam13479
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.
 5-58 3.23e-03

AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.


Pssm-ID: 433243  Cd Length: 199  Bit Score: 36.54  E-value: 3.23e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 495778694    5 IFLVGPRGCGKTTVGLELARVChrqFVDTDHWLQTEAGKTIADIVEQEGWESFR 58
Cdd:pfam13479   5 ILIYGPSGIGKTTFAKTLPKPL---FLDTEKGSKALDGDRFPDIVIRDSWQDFL 55
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 5-34 3.24e-03

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 36.08  E-value: 3.24e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 495778694   5 IFLVGPRGCGKTTVGLELARVCHRQFVDTD 34
Cdd:cd02021    2 IVVMGVSGSGKSTVGKALAERLGAPFIDGD 31
RecA-like cd01393
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 7-53 9.41e-03

RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.


Pssm-ID: 410881 [Multi-domain]  Cd Length: 185  Bit Score: 35.41  E-value: 9.41e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 495778694   7 LVGPRGCGKTTVGLELARVCHRQ-----FVDTDHWLQTEAGKTIADIVEQEG 53
Cdd:cd01393    6 IYGPPGSGKTQLALQLAANALLLgggvvWIDTEGAFPPSRLVQILEASPSSE 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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