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Conserved domains on  [gi|495778822|ref|WP_008503401|]
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MULTISPECIES: taurine ABC transporter permease TauC [Enterobacter]

Protein Classification

taurine ABC transporter permease TauC( domain architecture ID 10793353)

taurine ABC transporter permease TauC is part of a binding-protein-dependent transport system for taurine

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10160 PRK10160
taurine ABC transporter permease TauC;
1-275 6.99e-161

taurine ABC transporter permease TauC;


:

Pssm-ID: 182276  Cd Length: 275  Bit Score: 447.69  E-value: 6.99e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822   1 MSIVFSEKTRRTRLALRWPFSRQITLSVGTLLVLLAVWWAVAALQWVSPLFLPPPGQVLTKLITIAGPQGFMDATLWQHL 80
Cdd:PRK10160   1 MSVLINEKLHSRRLKWRWPLSRQLTLSIGTLAVLLAVWWAVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  81 GASLARILVALLAAVIIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160
Cdd:PRK10160  81 AASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822 161 ALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240
Cdd:PRK10160 161 ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 495778822 241 VVLAGIAVIAAIAFGLELGLRALQRRLTPWHGEIQ 275
Cdd:PRK10160 241 VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ 275
 
Name Accession Description Interval E-value
PRK10160 PRK10160
taurine ABC transporter permease TauC;
1-275 6.99e-161

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 447.69  E-value: 6.99e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822   1 MSIVFSEKTRRTRLALRWPFSRQITLSVGTLLVLLAVWWAVAALQWVSPLFLPPPGQVLTKLITIAGPQGFMDATLWQHL 80
Cdd:PRK10160   1 MSVLINEKLHSRRLKWRWPLSRQLTLSIGTLAVLLAVWWAVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  81 GASLARILVALLAAVIIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160
Cdd:PRK10160  81 AASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822 161 ALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240
Cdd:PRK10160 161 ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 495778822 241 VVLAGIAVIAAIAFGLELGLRALQRRLTPWHGEIQ 275
Cdd:PRK10160 241 VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ 275
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 15-271 4.43e-71

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 219.25  E-value: 4.43e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  15 ALRWPFSRQITLSVGTLLVLLAVWWAVAALQWVSPLFLPPPGQVLTKLITIAGpqgfmDATLWQHLGASLARILVALLAA 94
Cdd:COG0600    3 TSTRRRLRRLLLPLLSLALLLALWELAARLGLVPPFLLPSPSAVLAALVELLA-----SGELWEHLLASLLRVLLGFALA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  95 VIIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIR 174
Cdd:COG0600   78 ALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822 175 AAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAAIAF 254
Cdd:COG0600  158 LARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGL 237

                        250
                 ....*....|....*..
gi 495778822 255 GLELGLRALQRRLTPWH 271
Cdd:COG0600  238 LLDLLLRLLERRLLRWR 254
ntrB TIGR01183
nitrate ABC transporter, permease protein; This model describes the nitrate transport permease ...
 70-233 3.48e-24

nitrate ABC transporter, permease protein; This model describes the nitrate transport permease in bacteria. This is gene product of ntrB. The nitrate transport permease is the integral membrane component of the nitrate transport system and belongs to the ATP-binding cassette (ABC) superfamily. At least in photosynthetic bacteria nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA, ntrB, ntrC, ntrD, narB. Functionally ntrC and ntrD resemble the ATP binding components of the binding protein-dependent transport systems. Mutational studies have shown that ntrB and ntrC are mandatory for nitrate accumulation. Nitrate reductase is encoded by narB. [Transport and binding proteins, Anions]


Pssm-ID: 130251  Cd Length: 202  Bit Score: 96.41  E-value: 3.48e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822   70 GFMDATLWQHLGASLARILVALLAAVIIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLI 149
Cdd:TIGR01183   9 GGTDKGLFWQIIASLTRVAVGFSIAAIIGIAVGILIGLSKFLNAALDPIFQVLRTIPPLAWLPIALAAFQDAQPAAIFVI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  150 YLAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFM 229
Cdd:TIGR01183  89 FITAIWPIIINTAVGVQQIPQDYNNVARVLKLSKSDYFLKVLLPAAVPYIFTGLRIAIGLSWLAIVAAEMLMGGVGIGFF 168


                  ....
gi 495778822  230 VQSA 233
Cdd:TIGR01183 169 IWDA 172
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 98-269 1.72e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.85  E-value: 1.72e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822   98 GIPVGIAMGLSP--TVRGILDPLIELYRPVPPLAYLPLMVI-----WFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQ 170
Cdd:pfam00528   1 GIPLGIIAALRRgrRLDRLLRPLIDLLQALPSFVLAILLVViailsILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  171 VRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIA 250
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAA 160

                         170
                  ....*....|....*....
gi 495778822  251 AIAFGLELGLRALQRRLTP 269
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDP 179
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 80-222 3.95e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.98  E-value: 3.95e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  80 LGASLARILVALLAAVIIGIPVGIAMGLS-PTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSK---------ILLI 149
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGilpglglpaLILA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495778822 150 YLAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAA 222
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153
 
Name Accession Description Interval E-value
PRK10160 PRK10160
taurine ABC transporter permease TauC;
1-275 6.99e-161

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 447.69  E-value: 6.99e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822   1 MSIVFSEKTRRTRLALRWPFSRQITLSVGTLLVLLAVWWAVAALQWVSPLFLPPPGQVLTKLITIAGPQGFMDATLWQHL 80
Cdd:PRK10160   1 MSVLINEKLHSRRLKWRWPLSRQLTLSIGTLAVLLAVWWAVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  81 GASLARILVALLAAVIIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160
Cdd:PRK10160  81 AASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822 161 ALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240
Cdd:PRK10160 161 ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 495778822 241 VVLAGIAVIAAIAFGLELGLRALQRRLTPWHGEIQ 275
Cdd:PRK10160 241 VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ 275
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 15-271 4.43e-71

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 219.25  E-value: 4.43e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  15 ALRWPFSRQITLSVGTLLVLLAVWWAVAALQWVSPLFLPPPGQVLTKLITIAGpqgfmDATLWQHLGASLARILVALLAA 94
Cdd:COG0600    3 TSTRRRLRRLLLPLLSLALLLALWELAARLGLVPPFLLPSPSAVLAALVELLA-----SGELWEHLLASLLRVLLGFALA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  95 VIIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIR 174
Cdd:COG0600   78 ALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822 175 AAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAAIAF 254
Cdd:COG0600  158 LARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGL 237

                        250
                 ....*....|....*..
gi 495778822 255 GLELGLRALQRRLTPWH 271
Cdd:COG0600  238 LLDLLLRLLERRLLRWR 254
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
34-271 2.15e-37

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 132.75  E-value: 2.15e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  34 LLAVWWAVAALQWVSPLFLPPPGQVLTKLITIAGpqgfmDATLWQHLGASLARILVALLAAVIIGIPVGIAMGLSPTVRG 113
Cdd:PRK11365  21 IVAVWQLASSVGWLSTRILPSPEGVVTAFWTLSA-----SGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGER 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822 114 ILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRTQVLLFVILP 193
Cdd:PRK11365  96 LLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILP 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 495778822 194 GALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAAIAFGLELGLRALQRRLTPWH 271
Cdd:PRK11365 176 GALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADVSAQLLERLWLRWN 253
ntrB TIGR01183
nitrate ABC transporter, permease protein; This model describes the nitrate transport permease ...
 70-233 3.48e-24

nitrate ABC transporter, permease protein; This model describes the nitrate transport permease in bacteria. This is gene product of ntrB. The nitrate transport permease is the integral membrane component of the nitrate transport system and belongs to the ATP-binding cassette (ABC) superfamily. At least in photosynthetic bacteria nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA, ntrB, ntrC, ntrD, narB. Functionally ntrC and ntrD resemble the ATP binding components of the binding protein-dependent transport systems. Mutational studies have shown that ntrB and ntrC are mandatory for nitrate accumulation. Nitrate reductase is encoded by narB. [Transport and binding proteins, Anions]


Pssm-ID: 130251  Cd Length: 202  Bit Score: 96.41  E-value: 3.48e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822   70 GFMDATLWQHLGASLARILVALLAAVIIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLI 149
Cdd:TIGR01183   9 GGTDKGLFWQIIASLTRVAVGFSIAAIIGIAVGILIGLSKFLNAALDPIFQVLRTIPPLAWLPIALAAFQDAQPAAIFVI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  150 YLAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFM 229
Cdd:TIGR01183  89 FITAIWPIIINTAVGVQQIPQDYNNVARVLKLSKSDYFLKVLLPAAVPYIFTGLRIAIGLSWLAIVAAEMLMGGVGIGFF 168


                  ....
gi 495778822  230 VQSA 233
Cdd:TIGR01183 169 IWDA 172
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 76-270 1.21e-16

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 76.25  E-value: 1.21e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  76 LWQHLGASLarilVALLAAVIIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFA 155
Cdd:COG1174   20 LLEHLLLVL----LALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAPAIIALVLYALL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822 156 PVAMSALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGL--GVGWSTLVAaeLIAAtRGLGFMVQSA 233
Cdd:COG1174   96 PILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAvqNIGTATLAA--LIGA-GGLGDLIFDG 172

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 495778822 234 GEFLATDVVLAGIAVIAAIAFGLELGLRALQRRLTPW 270
Cdd:COG1174  173 LQLNNTALILAGAILVALLALLVDLLLALLERLLTPR 209
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
77-230 1.43e-14

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 72.43  E-value: 1.43e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  77 WQHLGASLARILVALLAAVIIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAP 156
Cdd:PRK10952 143 WSQAMVTLALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPP 222

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 495778822 157 VAMSALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATrGLGFMV 230
Cdd:PRK10952 223 IVRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVG-GLGQMV 295
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 98-269 1.72e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.85  E-value: 1.72e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822   98 GIPVGIAMGLSP--TVRGILDPLIELYRPVPPLAYLPLMVI-----WFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQ 170
Cdd:pfam00528   1 GIPLGIIAALRRgrRLDRLLRPLIDLLQALPSFVLAILLVViailsILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  171 VRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIA 250
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAA 160

                         170
                  ....*....|....*....
gi 495778822  251 AIAFGLELGLRALQRRLTP 269
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDP 179
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 80-222 3.95e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.98  E-value: 3.95e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  80 LGASLARILVALLAAVIIGIPVGIAMGLS-PTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSK---------ILLI 149
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGilpglglpaLILA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495778822 150 YLAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIAA 222
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153
COG4986 COG4986
ABC-type anion transport system, duplicated permease component [Inorganic ion transport and ...
 21-227 4.68e-06

ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism];


Pssm-ID: 444010 [Multi-domain]  Cd Length: 576  Bit Score: 47.53  E-value: 4.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  21 SRQITLSVGTLLVLLAVWWAVAALQWVspLFLPPPGQVLTklITIAGpqgfmdatlwqhlGASLARILVALLAAVIIGIP 100
Cdd:COG4986  329 SRWLDRLWLALLALLVLYGLWRLLLFL--LTEVGLSEVLH--VFLLG-------------LLTLLRVVVLIALASLIWVP 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822 101 VGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWF-GIGETSKILLIYLAIFAP---VAMSALAGVKSAQQVRIRAA 176
Cdd:COG4986  392 VGVWIGLRPRLARRLQPVAQFLASFPANLLFPVAVLLIvRFGLNPNIWLSPLMILGTqwyILFNVIAGASAIPNDLREAA 471

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495778822 177 QSLGASRTQVLLFVILPGALPEILTGLRIGLGVGWSTLVAAELIA------ATRGLG 227
Cdd:COG4986  472 RNFGLRGWLWWRRLILPGIFPYYVTGAITASGGAWNASIVAEYVSwgdttlQATGLG 528
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 72-203 5.96e-06

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 46.20  E-value: 5.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  72 MDATLWQHLGASLARILVALLAAVIIGIPVGIAMGLS--------PTVRGILDPLIELYRPVPplaYLPLMVIWF----- 138
Cdd:COG2011    8 LWPLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTrpggllpnPVLYRVLGVIVNIFRSIP---FIILLVALIpltrl 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495778822 139 ----GIGETSKIL-LIYLAI--FAPVAMSALAGVKSAqqvRIRAAQSLGASRTQVLLFVILPGALPEILTGL 203
Cdd:COG2011   85 ivgtSIGTTAAIVpLTIAAIpfFARLVENALREVDPG---VIEAAQAMGASPWQIIFKVLLPEALPSLILGL 153
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 75-200 5.30e-04

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 40.60  E-value: 5.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822   75 TLWQHLGASLARILVALLAAVIIGIPVGI----AMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIY 150
Cdd:TIGR01097  55 RILKALLETLAMAILGTVLAAVLAVPLALlaarNITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALA 134

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 495778822  151 LAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEIL 200
Cdd:TIGR01097 135 FHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFL 184
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 76-200 5.40e-04

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 40.06  E-value: 5.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  76 LWQHLGASLARILVALLAAVIIGIPVGIAMGL-SPTVRGILDPLIELYRPVPPLayLPLMVIWFGIGEtskiLLIYLAIF 154
Cdd:COG0765   15 LLEGLLVTLLLTVLAIVLGLVLGLLLALARLSpNPVLRWLATAYVEFFRGTPLL--VQLFFIYFGLPL----LGIDLSPF 88

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495778822 155 --APVAMSALAGVKSAQQVR----------IRAAQSLGASRTQVLLFVILPGALPEIL 200
Cdd:COG0765   89 vaAVIALTLNSAAYLAEIVRagiqsvpkgqWEAARALGLSRWQTMRRIILPQALRIIL 146
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
5-203 1.00e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 40.14  E-value: 1.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822   5 FSEKTRRTRLALRWPFSRQITLSVGTLLVLLAVWWAVAALqwvsplFLPPPGQVLTKLITIAGPQGF---------MDAT 75
Cdd:COG1178  262 LRRRRRYATVGGRARRPRRVKLGRWRWLALALCLLLVLLG------LLLPLLALLLWSLTKALDDNLtldnyrfvlLDPS 335

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  76 LWQHLGASLARILVALLAAVIIGIPVGIAMGLSPT-VRGILDPLIELYRPVPP----LAYLPLMVIWFGIGETSKILLI- 149
Cdd:COG1178  336 LLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGrLARLLDRLAMLPYAVPGivlgLGLLLLFNRPLPLLLYGTLAILv 415

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 495778822 150 --YLAIFAPVAM-SALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTGL 203
Cdd:COG1178  416 laYVVRFLPFALrSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAA 472
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 71-202 1.54e-03

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 39.32  E-value: 1.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  71 FMDATLWQHLGASLARILVALLAAVIIGIPVGIAMG-LSPTVRGILDPLIELYRPVPPLAY-LPLMVIWFGIGETSKILL 148
Cdd:COG1177   54 FSDPRLLDALLNSLLIALLSTLLATVLGTPAALALArYRFRGRRLLLALLLLPLVVPGIVLgVALLLLFSALGLSGGLWG 133

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495778822 149 IYLAIFAP----VAMSALAGVKSAQQVRIRAAQSLGASRTQVLLFVILPGALPEILTG 202
Cdd:COG1177  134 LILAHVVFtlpfVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAG 191
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 28-200 2.37e-03

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 38.52  E-value: 2.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822  28 VGTLLVLLAVWWAVAALQWVSPLFLPPPGQVLTKLITIAGPQGFMDATLWQHLGASLARILVALLAAVIIGIPVGIA--- 104
Cdd:COG3639    1 LLLLALLALLVWSLWGLEFDLGRLIDGLPNLADFLSRFFPPDWSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLaar 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495778822 105 -MGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVA--MS-ALAGVKSAQqvrIRAAQSLG 180
Cdd:COG3639   81 nLAPNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHTIGFLGklFAeAIEEIDPGP---VEALRATG 157

                        170       180
                 ....*....|....*....|
gi 495778822 181 ASRTQVLLFVILPGALPEIL 200
Cdd:COG3639  158 ASRLQVIRYGVLPQVLPQFL 177
PstA COG0581
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 175-208 8.41e-03

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440346 [Multi-domain]  Cd Length: 259  Bit Score: 36.94  E-value: 8.41e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 495778822 175 AAQSLGASRTQVLLFVILPGALPEILTGLRIGLG 208
Cdd:COG0581  147 ASYALGATKWQTIRKVVLPAALPGILTGVILAIA 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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