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Conserved domains on  [gi|495800287|ref|WP_008524866|]
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FeoA family protein [Halorhabdus tiamatea]

Protein Classification

ferrous iron transport protein A( domain architecture ID 10004922)

ferrous iron transport protein A (FeoA) is part of the Feo (ferrous iron-transport) system that functions in the uptake of ferrous iron

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FeoA COG1918
Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];
5-72 4.72e-12

Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];


:

Pssm-ID: 441522  Cd Length: 73  Bit Score: 55.14  E-value: 4.72e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495800287  5 LADVGSGESVRLVAVP-DGDTRARLLRLGFLDGA-VEC-RHHIRKGPVIVRRNGTDLALGADLAAEIEIER 72
Cdd:COG1918   3 LSELKPGEKARIVRISgDGELRRRLLELGLVPGTeVEVvRKAPLGGPLVVRVGGTRIALRREEAAKILVEP 73
 
Name Accession Description Interval E-value
FeoA COG1918
Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];
5-72 4.72e-12

Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];


Pssm-ID: 441522  Cd Length: 73  Bit Score: 55.14  E-value: 4.72e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495800287  5 LADVGSGESVRLVAVP-DGDTRARLLRLGFLDGA-VEC-RHHIRKGPVIVRRNGTDLALGADLAAEIEIER 72
Cdd:COG1918   3 LSELKPGEKARIVRISgDGELRRRLLELGLVPGTeVEVvRKAPLGGPLVVRVGGTRIALRREEAAKILVEP 73
FeoA pfam04023
FeoA domain; This family includes FeoA a small protein, probably involved in Fe2+ transport. ...
 5-72 1.28e-09

FeoA domain; This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.


Pssm-ID: 461133  Cd Length: 74  Bit Score: 49.12  E-value: 1.28e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495800287   5 LADVGSGESVRLVAVPDGDT--RARLLRLGFLDGA-VECRHHIR-KGPVIVRRNGTDLALGADLAAEIEIER 72
Cdd:pfam04023  3 LSELKEGETARIVRIRDGDPelLRRLLELGLVPGAeVTVVRKAPfGGPIIVRVGGTRIALRREEASKIFVEP 74
FeoA smart00899
This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found ...
 5-72 7.00e-08

This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; This domain also occurs at the C-terminus in related proteins. The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located in the cytosol; FeoB, a large protein with a cytosolic N-terminal G-protein domain and a C-terminal integral inner-membrane domain containing two 'Gate' motifs which likely functions as the Fe2+ permease; and FeoC, a small protein apparently functioning as an [Fe-S]-dependent transcriptional repressor. Feo allows the bacterial cell to acquire iron from its environment.


Pssm-ID: 214896  Cd Length: 72  Bit Score: 44.87  E-value: 7.00e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495800287    5 LADVGSGESVRLVAVPDGD--TRARLLRLGFLDGA-VECRHHIRKGPVIVRRNGTdLALGADLAAEIEIER 72
Cdd:smart00899  3 LSELKPGEKARIVRIRDEDpeLLRRLLELGLVPGTeVTVLRKAPFGPLVVRVGGE-LALRREEAEKIFVEP 72
 
Name Accession Description Interval E-value
FeoA COG1918
Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];
5-72 4.72e-12

Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];


Pssm-ID: 441522  Cd Length: 73  Bit Score: 55.14  E-value: 4.72e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495800287  5 LADVGSGESVRLVAVP-DGDTRARLLRLGFLDGA-VEC-RHHIRKGPVIVRRNGTDLALGADLAAEIEIER 72
Cdd:COG1918   3 LSELKPGEKARIVRISgDGELRRRLLELGLVPGTeVEVvRKAPLGGPLVVRVGGTRIALRREEAAKILVEP 73
FeoA pfam04023
FeoA domain; This family includes FeoA a small protein, probably involved in Fe2+ transport. ...
 5-72 1.28e-09

FeoA domain; This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.


Pssm-ID: 461133  Cd Length: 74  Bit Score: 49.12  E-value: 1.28e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 495800287   5 LADVGSGESVRLVAVPDGDT--RARLLRLGFLDGA-VECRHHIR-KGPVIVRRNGTDLALGADLAAEIEIER 72
Cdd:pfam04023  3 LSELKEGETARIVRIRDGDPelLRRLLELGLVPGAeVTVVRKAPfGGPIIVRVGGTRIALRREEASKIFVEP 74
FeoA smart00899
This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found ...
 5-72 7.00e-08

This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; This domain also occurs at the C-terminus in related proteins. The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located in the cytosol; FeoB, a large protein with a cytosolic N-terminal G-protein domain and a C-terminal integral inner-membrane domain containing two 'Gate' motifs which likely functions as the Fe2+ permease; and FeoC, a small protein apparently functioning as an [Fe-S]-dependent transcriptional repressor. Feo allows the bacterial cell to acquire iron from its environment.


Pssm-ID: 214896  Cd Length: 72  Bit Score: 44.87  E-value: 7.00e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495800287    5 LADVGSGESVRLVAVPDGD--TRARLLRLGFLDGA-VECRHHIRKGPVIVRRNGTdLALGADLAAEIEIER 72
Cdd:smart00899  3 LSELKPGEKARIVRIRDEDpeLLRRLLELGLVPGTeVTVLRKAPFGPLVVRVGGE-LALRREEAEKIFVEP 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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