NCBI Conserved Domain Search

NCBI

3D Macromolecular Structures

Conserved Domains

Conserved domains on [gi|495915227|ref|WP_008639806|]

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collagen-like triple helix repeat-containing protein [Halobacillus sp. BAB-2008]

Protein Classification

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

BclA_C

BclA C-terminal domain; This is the C-terminal domain of BclA (Bacillus collagen-like protein ...

81-207

5.92e-52

BclA C-terminal domain; This is the C-terminal domain of BclA (Bacillus collagen-like protein of anthracis) which is expressed on spores of Bacillus species. Trimers of the C-terminal domain (CTD) form the tips of the spore's hair-like nap and are the immunodominant target of vertebrate antibodies and drive trimerization. Structure analysis indicate the C-terminal region of the peptide folding into an all-beta structure with a jelly-fold topology, similar to the first human complement C1q, a member of the tumor necrosis factor (TNF)-like family. The C-terminal globular domain has been shown to be located on the exterior of the exosporium, and therefore is critical in determining the immunogenicity of the spore in a mammalian host.

:

Pssm-ID: 436587 [Multi-domain] Cd Length: 127 Bit Score: 163.60 E-value: 5.92e-52

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227   81 FAANTEGALIAVVLGGTTVPLPNSQNVKNITVDPTDTVFTITLSGRYYLSYKVNTTAALLLGARLTVNGTPLEASETNPV 160
Cdd:pfam18573   1 YAANTSGSTIAVVLGGTPVPLPNNQNLSGITVNGTNTTFTVNEAGRYYISYQVNTTAALLVGLRLLVNGTPVPGSIITPA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 495915227  161 LSVSSFNADIIVSLDVGDTISLELFGLLGAATLQDGQGATLTIIRID 207
Cdd:pfam18573  81 LSTSSYSNSVIVTLTAGDTISLQLFGLAGAATLGGGTGASLTIIRLA 127

gly_rich_SclB super family

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

4-73

1.02e-19

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 86.11 E-value: 1.02e-19

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227   4 NFYDGSGDCVRGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 109 GLQQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGK 178

Name

Accession

Description

Interval

E-value

BclA_C

BclA C-terminal domain; This is the C-terminal domain of BclA (Bacillus collagen-like protein ...

81-207

5.92e-52

BclA C-terminal domain; This is the C-terminal domain of BclA (Bacillus collagen-like protein of anthracis) which is expressed on spores of Bacillus species. Trimers of the C-terminal domain (CTD) form the tips of the spore's hair-like nap and are the immunodominant target of vertebrate antibodies and drive trimerization. Structure analysis indicate the C-terminal region of the peptide folding into an all-beta structure with a jelly-fold topology, similar to the first human complement C1q, a member of the tumor necrosis factor (TNF)-like family. The C-terminal globular domain has been shown to be located on the exterior of the exosporium, and therefore is critical in determining the immunogenicity of the spore in a mammalian host.

Pssm-ID: 436587 [Multi-domain] Cd Length: 127 Bit Score: 163.60 E-value: 5.92e-52

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227   81 FAANTEGALIAVVLGGTTVPLPNSQNVKNITVDPTDTVFTITLSGRYYLSYKVNTTAALLLGARLTVNGTPLEASETNPV 160
Cdd:pfam18573   1 YAANTSGSTIAVVLGGTPVPLPNNQNLSGITVNGTNTTFTVNEAGRYYISYQVNTTAALLVGLRLLVNGTPVPGSIITPA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 495915227  161 LSVSSFNADIIVSLDVGDTISLELFGLLGAATLQDGQGATLTIIRID 207
Cdd:pfam18573  81 LSTSSYSNSVIVTLTAGDTISLQLFGLAGAATLGGGTGASLTIIRLA 127

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

4-73

1.02e-19

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 86.11 E-value: 1.02e-19

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227   4 NFYDGSGDCVRGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 109 GLQQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGK 178

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-73

5.97e-18

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 81.10 E-value: 5.97e-18

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 155 QGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGP 214

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-73

1.87e-17

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 79.95 E-value: 1.87e-17

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495915227  14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGE---TGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGErgeKGPAGPQGEAGPQGPAGKDGEAGA 184

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-73

1.96e-17

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 79.56 E-value: 1.96e-17

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 131 AGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGE 190

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-73

3.86e-17

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 78.79 E-value: 3.86e-17

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 165 GPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGE 223

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-73

1.35e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 77.25 E-value: 1.35e-16

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 144 GPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGP 202

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-74

1.55e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 77.25 E-value: 1.55e-16

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPV 74
Cdd:NF038329 150 GPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPA 209

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-73

7.34e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 75.33 E-value: 7.34e-16

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 162 GPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGP 220

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-72

3.47e-15

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 73.40 E-value: 3.47e-15

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495915227  14 RGLRGPEGPAGPA------GPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:NF038329 167 QGEAGPQGPAGKDgeagakGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAG 231

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

10-72

1.15e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 71.86 E-value: 1.15e-14

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495915227  10 GDCVRGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:NF038329 228 GPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDG 290

Collagen

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...

18-74

1.20e-14

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.

Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 65.59 E-value: 1.20e-14

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 495915227   18 GPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPV 74
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

20-74

2.35e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 70.70 E-value: 2.35e-14

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 495915227  20 EGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPV 74
Cdd:NF038329 116 DGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEA 170

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

10-73

1.02e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 68.78 E-value: 1.02e-13

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  10 GDCVRGLRGPEGPAGPAGPQGEAGPAGPQG------ETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 231 GDGQQGPDGDPGPTGEDGPQGPDGPAGKDGprgdrgEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGK 300

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-72

1.07e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 63.00 E-value: 1.07e-11

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:NF038329 248 GPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDG 305

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-72

2.79e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 47.21 E-value: 2.79e-06

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:NF038329 277 DGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335

SPT5

Transcription elongation factor SPT5 [Transcription];

15-72

1.70e-05

Transcription elongation factor SPT5 [Transcription];

Pssm-ID: 444063 [Multi-domain] Cd Length: 495 Bit Score: 44.64 E-value: 1.70e-05

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:COG5164   10 GPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGSTTPAGNTGGTRPAG 67

PHA03247

large tegument protein UL36; Provisional

13-73

6.08e-05

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.39 E-value: 6.08e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495915227   13 VRGLRGPEGP--AGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:PHA03247 2716 VSATPLPPGPaaARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAG 2778

Name

Accession

Description

Interval

E-value

BclA_C

BclA C-terminal domain; This is the C-terminal domain of BclA (Bacillus collagen-like protein ...

81-207

5.92e-52

BclA C-terminal domain; This is the C-terminal domain of BclA (Bacillus collagen-like protein of anthracis) which is expressed on spores of Bacillus species. Trimers of the C-terminal domain (CTD) form the tips of the spore's hair-like nap and are the immunodominant target of vertebrate antibodies and drive trimerization. Structure analysis indicate the C-terminal region of the peptide folding into an all-beta structure with a jelly-fold topology, similar to the first human complement C1q, a member of the tumor necrosis factor (TNF)-like family. The C-terminal globular domain has been shown to be located on the exterior of the exosporium, and therefore is critical in determining the immunogenicity of the spore in a mammalian host.

Pssm-ID: 436587 [Multi-domain] Cd Length: 127 Bit Score: 163.60 E-value: 5.92e-52

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227   81 FAANTEGALIAVVLGGTTVPLPNSQNVKNITVDPTDTVFTITLSGRYYLSYKVNTTAALLLGARLTVNGTPLEASETNPV 160
Cdd:pfam18573   1 YAANTSGSTIAVVLGGTPVPLPNNQNLSGITVNGTNTTFTVNEAGRYYISYQVNTTAALLVGLRLLVNGTPVPGSIITPA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 495915227  161 LSVSSFNADIIVSLDVGDTISLELFGLLGAATLQDGQGATLTIIRID 207
Cdd:pfam18573  81 LSTSSYSNSVIVTLTAGDTISLQLFGLAGAATLGGGTGASLTIIRLA 127

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

4-73

1.02e-19

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 86.11 E-value: 1.02e-19

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227   4 NFYDGSGDCVRGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 109 GLQQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGK 178

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-73

5.97e-18

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 81.10 E-value: 5.97e-18

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 155 QGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGP 214

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-73

1.87e-17

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 79.95 E-value: 1.87e-17

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495915227  14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGE---TGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGErgeKGPAGPQGEAGPQGPAGKDGEAGA 184

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-73

1.96e-17

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 79.56 E-value: 1.96e-17

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 131 AGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGE 190

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-73

3.86e-17

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 78.79 E-value: 3.86e-17

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 165 GPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGE 223

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-73

1.35e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 77.25 E-value: 1.35e-16

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 144 GPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGP 202

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-74

1.55e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 77.25 E-value: 1.55e-16

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPV 74
Cdd:NF038329 150 GPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPA 209

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-73

7.34e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 75.33 E-value: 7.34e-16

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 162 GPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGP 220

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-72

3.47e-15

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 73.40 E-value: 3.47e-15

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495915227  14 RGLRGPEGPAGPA------GPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:NF038329 167 QGEAGPQGPAGKDgeagakGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAG 231

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

10-72

1.15e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 71.86 E-value: 1.15e-14

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495915227  10 GDCVRGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:NF038329 228 GPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDG 290

Collagen

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...

18-74

1.20e-14

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.

Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 65.59 E-value: 1.20e-14

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 495915227   18 GPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPV 74
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

20-74

2.35e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 70.70 E-value: 2.35e-14

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 495915227  20 EGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPV 74
Cdd:NF038329 116 DGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEA 170

Collagen

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...

15-71

9.33e-14

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.

Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 63.28 E-value: 9.33e-14

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 495915227   15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPA 71
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

10-73

1.02e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 68.78 E-value: 1.02e-13

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  10 GDCVRGLRGPEGPAGPAGPQGEAGPAGPQG------ETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:NF038329 231 GDGQQGPDGDPGPTGEDGPQGPDGPAGKDGprgdrgEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGK 300

Collagen

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...

14-65

6.93e-12

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.

Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 58.27 E-value: 6.93e-12

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 495915227   14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEV 65
Cdd:pfam01391   6 PGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

15-72

1.07e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 63.00 E-value: 1.07e-11

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:NF038329 248 GPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDG 305

gly_rich_SclB

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...

14-72

2.79e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.

Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 47.21 E-value: 2.79e-06

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:NF038329 277 DGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335

SPT5

Transcription elongation factor SPT5 [Transcription];

15-72

1.70e-05

Transcription elongation factor SPT5 [Transcription];

Pssm-ID: 444063 [Multi-domain] Cd Length: 495 Bit Score: 44.64 E-value: 1.70e-05

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495915227  15 GLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:COG5164   10 GPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGSTTPAGNTGGTRPAG 67

SPT5

Transcription elongation factor SPT5 [Transcription];

15-73

2.37e-05

Transcription elongation factor SPT5 [Transcription];

Pssm-ID: 444063 [Multi-domain] Cd Length: 495 Bit Score: 44.25 E-value: 2.37e-05

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  15 GLRGPeGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:COG5164    2 GLYGP-GKTGPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGSTTPAGN 59

SPT5

Transcription elongation factor SPT5 [Transcription];

18-103

5.73e-05

Transcription elongation factor SPT5 [Transcription];

Pssm-ID: 444063 [Multi-domain] Cd Length: 495 Bit Score: 43.09 E-value: 5.73e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  18 GPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG------PVVTETSGFAANTEGALIA 91
Cdd:COG5164   40 GNTGGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPAQNQGGTTPAQNQGGTRPAGntggttPAGDGGATGPPDDGGATGP 119

                         90
                 ....*....|..
gi 495915227  92 VVLGGTTVPLPN 103
Cdd:COG5164  120 PDDGGSTTPPSG 131

PHA03247

large tegument protein UL36; Provisional

13-73

6.08e-05

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.39 E-value: 6.08e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495915227   13 VRGLRGPEGP--AGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:PHA03247 2716 VSATPLPPGPaaARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAG 2778

PHA03169

hypothetical protein; Provisional

18-72

8.67e-05

hypothetical protein; Provisional

Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 42.65 E-value: 8.67e-05

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 495915227  18 GPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:PHA03169 150 APPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPP 204

PHA03247

large tegument protein UL36; Provisional

19-83

1.33e-04

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 1.33e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 495915227   19 PEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPVVTETSGFAA 83
Cdd:PHA03247 2733 PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRES 2797

PHA03247

large tegument protein UL36; Provisional

19-118

1.41e-04

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 1.41e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227   19 PEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPVVTETSGFAANTEGALIAVVLGGTT 98
Cdd:PHA03247 2736 PAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPA 2815

                          90       100
                  ....*....|....*....|
gi 495915227   99 VPLPNSQNVKNITVDPTDTV 118
Cdd:PHA03247 2816 AALPPAASPAGPLPPPTSAQ 2835

PHA03169

hypothetical protein; Provisional

18-86

1.73e-04

hypothetical protein; Provisional

Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 41.49 E-value: 1.73e-04

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  18 GPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPVVTETSGFAANTE 86
Cdd:PHA03169 174 SPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPER 242

PHA03169

hypothetical protein; Provisional

9-73

2.55e-04

hypothetical protein; Provisional

Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 41.11 E-value: 2.55e-04

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495915227   9 SGDCVRGLRGPEGPAGPAGPQ----------GEAGPAGPQGETGPAGPQGETGPA--GPQGEAGPQGEVGPAGPAGP 73
Cdd:PHA03169  93 SGSGSESVGSPTPSPSGSAEElasglspentSGSSPESPASHSPPPSPPSHPGPHepAPPESHNPSPNQQPSSFLQP 169

PHA03247

large tegument protein UL36; Provisional

18-104

4.68e-04

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 40.69 E-value: 4.68e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227   18 GPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPVVTETSGFAANTEGALIAVVLGGT 97
Cdd:PHA03247 2747 GPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826


                  ....*..
gi 495915227   98 TVPLPNS 104
Cdd:PHA03247 2827 PLPPPTS 2833

PHA03169

hypothetical protein; Provisional

18-73

6.38e-04

hypothetical protein; Provisional

Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 39.95 E-value: 6.38e-04

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 495915227  18 GPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:PHA03169 159 PNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEP 214

PTZ00449

104 kDa microneme/rhoptry antigen; Provisional

17-79

6.74e-04

104 kDa microneme/rhoptry antigen; Provisional

Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 40.06 E-value: 6.74e-04

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 495915227  17 RGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPVVTETS 79
Cdd:PTZ00449 595 KKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSP 657

C1q

C1q domain; C1q is a subunit of the C1 enzyme complex that activates the serum complement ...

113-186

7.34e-04

C1q domain; C1q is a subunit of the C1 enzyme complex that activates the serum complement system.

Pssm-ID: 395310 [Multi-domain] Cd Length: 126 Bit Score: 38.03 E-value: 7.34e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 495915227  113 DPTDTVFTITLSGRYYLSYKVNTTAALLLGARLTVNG---TPLEASETNPVLSVSSfnADIIVSLDVGDTISLELFG 186
Cdd:pfam00386  32 DPATGKFTCPVPGVYYFSYHITTVDGKSLYVSLVKNGqevVSFYDQPQKGSLDVAS--GSVVLELQRGDEVWLQLTG 106

PHA03169

hypothetical protein; Provisional

18-72

1.06e-03

hypothetical protein; Provisional

Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 39.18 E-value: 1.06e-03

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  18 GPEGPAGPA--GPQGEAGPAGPQGETGPAGPQGETG---PAGPQGEAGPQGEVGPAGPAG 72
Cdd:PHA03169 139 SPPSHPGPHepAPPESHNPSPNQQPSSFLQPSHEDSpeePEPPTSEPEPDSPGPPQSETP 198

PHA03169

hypothetical protein; Provisional

18-73

1.70e-03

hypothetical protein; Provisional

Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 38.80 E-value: 1.70e-03

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495915227  18 GPEGPAGPAGPQGEAGPA--GPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:PHA03169 130 SPASHSPPPSPPSHPGPHepAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEP 187

PHA03169

hypothetical protein; Provisional

18-73

1.90e-03

hypothetical protein; Provisional

Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 38.41 E-value: 1.90e-03

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495915227  18 GPEGPAGPAGPQGEAGPAGPQGETGPAGPQ--GETGPAGPQGEAGPQGEVGPAGPAGP 73
Cdd:PHA03169 124 SGSSPESPASHSPPPSPPSHPGPHEPAPPEshNPSPNQQPSSFLQPSHEDSPEEPEPP 181

PHA03264

envelope glycoprotein D; Provisional

22-75

2.51e-03

envelope glycoprotein D; Provisional

Pssm-ID: 223029 [Multi-domain] Cd Length: 416 Bit Score: 38.06 E-value: 2.51e-03

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227  22 PAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQG---EAGPQGE--VGPAGPAGPVV 75
Cdd:PHA03264 275 PAPPGDDRPEAKPEPGPVEDGAPGRETGGEGEGPEPagrDGAAGGEpkPGPPRPAPDAD 333

PHA03169

hypothetical protein; Provisional

7-73

3.50e-03

hypothetical protein; Provisional

Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 37.64 E-value: 3.50e-03

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495915227   7 DGSGDCVRGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGE--VGPAGPAGP 73
Cdd:PHA03169 175 PEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEheDEPTEPERE 243

PHA03169

hypothetical protein; Provisional

18-72

3.80e-03

hypothetical protein; Provisional

Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 37.64 E-value: 3.80e-03

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 495915227  18 GPEGPAGPAGPQGEAGPAGPQGET---GPAGPQGETGPAGPQGEAGPQGEVGPAGPAG 72
Cdd:PHA03169 162 QPSSFLQPSHEDSPEEPEPPTSEPepdSPGPPQSETPTSSPPPQSPPDEPGEPQSPTP 219

PRK07764

DNA polymerase III subunits gamma and tau; Validated

14-100

5.33e-03

DNA polymerase III subunits gamma and tau; Validated

Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 37.27 E-value: 5.33e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495915227  14 RGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPVVTETSGFAANTEGALIAVV 93
Cdd:PRK07764 592 PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPA 671


                 ....*..
gi 495915227  94 LGGTTVP 100
Cdd:PRK07764 672 KAGGAAP 678

PRK07764

DNA polymerase III subunits gamma and tau; Validated

13-83

5.99e-03

DNA polymerase III subunits gamma and tau; Validated

Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 37.27 E-value: 5.99e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495915227  13 VRGLRGPEGPAGPAGPQGEAGPAGPQGETGPAGPQGETGPAGPQGEAGPQGEVGPAGPAGPVVTETSGFAA 83
Cdd:PRK07764 387 VAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPP 457

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01

References:

Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

Functional characterization of the conserved domain architecture found on the query. Click here to see more details.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the domain model's accession number to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options