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Conserved domains on  [gi|496059549|ref|WP_008784056|]
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MULTISPECIES: iron-enterobactin ABC transporter permease [Citrobacter]

Protein Classification

iron-enterobactin ABC transporter permease( domain architecture ID 10793391)

iron-enterobactin ABC transporter permease is part of the binding-protein-dependent transport system for ferric enterobactin

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-330 4.34e-177

iron-enterobactin ABC transporter permease;


:

Pssm-ID: 182463  Cd Length: 330  Bit Score: 493.46  E-value: 4.34e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   1 MMHLSRRLIISSLLLVAGCLVIGLWSLRSGVVTLETQQIIAALLGDAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIF 80
Cdd:PRK10440   1 MIYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMLGGILTSLVVWALAWRNGIDTFRLIIIGIGIRAMLVA 160
Cdd:PRK10440  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMML 240
Cdd:PRK10440 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLML 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 241 VAVVLTAAATALAGPISFIALVAPHIARRISGTSRWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320
Cdd:PRK10440 241 VAVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320

                        330
                 ....*....|
gi 496059549 321 VLLIQESRKK 330
Cdd:PRK10440 321 VLLIQESRKK 330
 
Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-330 4.34e-177

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 493.46  E-value: 4.34e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   1 MMHLSRRLIISSLLLVAGCLVIGLWSLRSGVVTLETQQIIAALLGDAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIF 80
Cdd:PRK10440   1 MIYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMLGGILTSLVVWALAWRNGIDTFRLIIIGIGIRAMLVA 160
Cdd:PRK10440  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMML 240
Cdd:PRK10440 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLML 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 241 VAVVLTAAATALAGPISFIALVAPHIARRISGTSRWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320
Cdd:PRK10440 241 VAVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320

                        330
                 ....*....|
gi 496059549 321 VLLIQESRKK 330
Cdd:PRK10440 321 VLLIQESRKK 330
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 4-329 6.32e-117

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 341.33  E-value: 6.32e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   4 LSRRLIISSLLLVAGCLVIGLWSLRSGVVTLETQQIIAALLGDAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIFQSL 83
Cdd:COG4779   18 LRRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  84 MRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMLGGILTSLVVWALAWRNGIDTFRLIIIGIGIRAMLVAFNT 163
Cdd:COG4779   98 TRNPLASPDIIGITAGASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNS 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 164 WLLLKASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLVAV 243
Cdd:COG4779  178 YLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAV 257

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 244 VLTAAATALAGPISFIALVAPHIARRISGTSRWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLL 323
Cdd:COG4779  258 ALAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLL 337


                 ....*.
gi 496059549 324 IQESRK 329
Cdd:COG4779  338 IRENRR 343
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 19-325 1.16e-68

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 217.01  E-value: 1.16e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   19 CLVIGLWSLRSGVVTLETQQIIAALLGDAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNT 98
Cdd:pfam01032   2 LLLLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   99 GAWSGVLVAMVLFG-QHLTAIALAAMLGGILTSLVVWALA-WRNGIDTFRLIIIGIGIRAMLVAFNTWLLLKASLETALT 176
Cdd:pfam01032  82 GAALGAVLAILLGGsLSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  177 AGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPI 256
Cdd:pfam01032 162 ILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPI 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  257 SFIALVAPHIARRISGTS-RWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQ 325
Cdd:pfam01032 242 GFVGLIVPHIARLLVGANhRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 63-323 8.36e-43

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 148.47  E-value: 8.36e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  63 VLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQH-LTAIALAAMLGGILTSLVVWALAWRNG 141
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLsNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 142 IDTFRLIIIGIGIRAMLVAFNTWLLLKASlETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGD 221
Cdd:cd06550   81 LSPSKLILIGIVLSAFFSAGVILISLLSD-DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 222 DSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTS-RWGLTLSALCGALLLLMADLCAQQLF 300
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRShRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|...
gi 496059549 301 mPYQLPVGVVTVSLGGIYLIVLL 323
Cdd:cd06550  240 -PSELPVGPVTALLGAPYFLYLL 261
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 54-328 3.50e-28

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 111.49  E-value: 3.50e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   54 VVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQhlTAIALAAMLGGILTSLVV 133
Cdd:TIGR03869  48 IVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVA--VLLPVAAFAGALLALAAT 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  134 WALAWRNGIDTFRLIIIGIGIRAMLVAFNTWLLL--KASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLV 211
Cdd:TIGR03869 126 LGLARTLGTLTPTRTILAGLAVSQLCAAVTSFVIfwSATGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASG 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  212 RRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTS-RWGLTLSALCGALLLL 290
Cdd:TIGR03869 206 RVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRhRLLLPVSALAGAVFLV 285

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 496059549  291 MADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 328
Cdd:TIGR03869 286 WADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
 
Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-330 4.34e-177

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 493.46  E-value: 4.34e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   1 MMHLSRRLIISSLLLVAGCLVIGLWSLRSGVVTLETQQIIAALLGDAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIF 80
Cdd:PRK10440   1 MIYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMLGGILTSLVVWALAWRNGIDTFRLIIIGIGIRAMLVA 160
Cdd:PRK10440  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMML 240
Cdd:PRK10440 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLML 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 241 VAVVLTAAATALAGPISFIALVAPHIARRISGTSRWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320
Cdd:PRK10440 241 VAVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320

                        330
                 ....*....|
gi 496059549 321 VLLIQESRKK 330
Cdd:PRK10440 321 VLLIQESRKK 330
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 4-329 6.32e-117

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 341.33  E-value: 6.32e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   4 LSRRLIISSLLLVAGCLVIGLWSLRSGVVTLETQQIIAALLGDAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIFQSL 83
Cdd:COG4779   18 LRRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  84 MRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMLGGILTSLVVWALAWRNGIDTFRLIIIGIGIRAMLVAFNT 163
Cdd:COG4779   98 TRNPLASPDIIGITAGASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNS 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 164 WLLLKASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLVAV 243
Cdd:COG4779  178 YLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAV 257

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 244 VLTAAATALAGPISFIALVAPHIARRISGTSRWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLL 323
Cdd:COG4779  258 ALAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLL 337


                 ....*.
gi 496059549 324 IQESRK 329
Cdd:COG4779  338 IRENRR 343
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 19-325 1.16e-68

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 217.01  E-value: 1.16e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   19 CLVIGLWSLRSGVVTLETQQIIAALLGDAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNT 98
Cdd:pfam01032   2 LLLLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   99 GAWSGVLVAMVLFG-QHLTAIALAAMLGGILTSLVVWALA-WRNGIDTFRLIIIGIGIRAMLVAFNTWLLLKASLETALT 176
Cdd:pfam01032  82 GAALGAVLAILLGGsLSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  177 AGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPI 256
Cdd:pfam01032 162 ILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPI 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  257 SFIALVAPHIARRISGTS-RWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQ 325
Cdd:pfam01032 242 GFVGLIVPHIARLLVGANhRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 26-324 6.28e-67

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 212.24  E-value: 6.28e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  26 SLRSGVVTLETQQIIAALLGDAPRSIT-LVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGV 104
Cdd:COG0609    1 SLSLGAVPISLSDVLRALLGPDGDPTAdLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 105 LVAMVLFGQ-HLTAIALAAMLGGILTSLVVWALAWRN-GIDTFRLIIIGIGIRAMLVAFNTWLLLKASLETALTAGLWNA 182
Cdd:COG0609   81 VLAIVLGGGlSALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWLM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 183 GSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALV 262
Cdd:COG0609  161 GSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLV 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 496059549 263 APHIARRISGTS-RWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLI 324
Cdd:COG0609  241 VPHIARLLVGPDhRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLR 303
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
3-329 1.99e-49

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 174.64  E-value: 1.99e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   3 HLSRRLIISSLLLVAGCLVIGLWSLrsGVVTLETQQIIAALLGDAPRSitlvVTEWRLPRVLMALLIGAALGVSGAIFQS 82
Cdd:PRK10577 347 VAARRRRVLAWLLALGLLLLLALVV--ALSFGRDAHGWNWLSGQLLDA----LLPLRLPRLLAALLAGAMLAVAGTLLQR 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  83 LMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQH-LTAIALAAMLGGILTSLVVWALAWRNGIDTFRLIIIGIGIRAMLVAF 161
Cdd:PRK10577 421 LTRNPLASPEVLGISSGAGLGVVLALFLVPGAgFGWLLAAALLGALAALALILLLARRGGFAPERLLLTGIALSALFTAL 500

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 162 NTWLLLKASLETAlTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLV 241
Cdd:PRK10577 501 IQLLLASGDPRAA-QLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARLALLLL 579

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 242 AVVLTAAATALAGPISFIALVAPHIARRISG-TSRWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320
Cdd:PRK10577 580 AALLTAAATATVGPLSFVGLMAPHLARMLGGrRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFL 659


                 ....*....
gi 496059549 321 VLLIQESRK 329
Cdd:PRK10577 660 WLLRRSRRR 668
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-323 5.68e-45

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 162.70  E-value: 5.68e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   1 MMHLSRRLIISSLLLVAGCLVIGLWSLRSGVVTLETQQIIAALLGDAPRSI-TLVVTEWRLPRVLMALLIGAALGVSGAI 79
Cdd:PRK10577   3 RLMSRRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLeQLLLHYSRLPRLAIALLVGAALGLAGAL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  80 FQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIA-LAAMLGGILTSLVVWALAWRNGIDTFRLIIIGIGIRAML 158
Cdd:PRK10577  83 LQQVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASqLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 159 VAFNTWLLLkASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMM 238
Cdd:PRK10577 163 GALTTLLLL-FNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAA 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 239 MLVAVVLTAAATALAGPISFIALVAPHIARRISG-TSRWGLTLSALCGALLLLMADLCAQQL--FMPYQLPVGVVTVSLG 315
Cdd:PRK10577 242 LALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGArRLRARLPLSPLIGALLLLLTDQLVRLLagVGGELLPTGAVTALIG 321


                 ....*...
gi 496059549 316 GIYLIVLL 323
Cdd:PRK10577 322 APLLLWLL 329
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
6-325 8.66e-45

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 155.20  E-value: 8.66e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   6 RRLIISSLLLVAGCLVIglwSLRSGVVTLETQQIIAALLGDAPRSITLvvTEWRLPRVLMALLIGAALGVSGAIFQSLMR 85
Cdd:PRK09777   3 IALVIFITLALAGCALL---SLRMGVIPLPWRALLTDWQAGDEHYYVL--MEYRLPRLLLALFVGAALAVSGVLVQGIVR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  86 NPLGSPDVMGFNTGAWSGVLVAMVLF-GQHLTAIALAAMLGGILTSLVVWALAWRNgiDTFRLIIIGIGIRAMLVAFNTW 164
Cdd:PRK09777  78 NPLASPDILGVNHAASLASVGALLLFpSLPVMWLPLLAFIGGMAGLILLKMLAGTH--QPMKLALTGVALSALWASLTDY 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 165 LLLKASLETAlTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLVAVV 244
Cdd:PRK09777 156 LMLSRPQDIN-NALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVA 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 245 LTAAATALAGPISFIALVAPHIARRI-SGTSRWGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLL 323
Cdd:PRK09777 235 LTATGVAACGPISFIGLVVPHLMRSLvGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLL 314


                 ..
gi 496059549 324 IQ 325
Cdd:PRK09777 315 VR 316
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 63-323 8.36e-43

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 148.47  E-value: 8.36e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  63 VLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQH-LTAIALAAMLGGILTSLVVWALAWRNG 141
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLsNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 142 IDTFRLIIIGIGIRAMLVAFNTWLLLKASlETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGD 221
Cdd:cd06550   81 LSPSKLILIGIVLSAFFSAGVILISLLSD-DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 222 DSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTS-RWGLTLSALCGALLLLMADLCAQQLF 300
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRShRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|...
gi 496059549 301 mPYQLPVGVVTVSLGGIYLIVLL 323
Cdd:cd06550  240 -PSELPVGPVTALLGAPYFLYLL 261
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 53-324 1.77e-35

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 131.13  E-value: 1.77e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  53 LVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLT--AIALAAMLGGILTS 130
Cdd:COG4139   49 LFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLLGGGLLPpwLLSLAAIAGALLVT 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 131 LVVWALAwRNGIDTFRLIIIGIGIRAMLVAFNTWLLLKASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIImLVCAALL 210
Cdd:COG4139  129 LLLLAFA-RRRLSNARLLLIGVALGIICSAIMTWAVYFSSSLDLRQLMYWMMGSFGGVDWRQLWLLLALLPV-LLWLCLQ 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 211 VRRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTS-RWGLTLSALCGALLL 289
Cdd:COG4139  207 GKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDhRFLLPACALAGAALL 286

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 496059549 290 LMADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLI 324
Cdd:COG4139  287 LLADIIARLALSSAELPIGVVTATLGAPVFIWLLL 321
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
41-315 1.42e-34

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 128.66  E-value: 1.42e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  41 AALLGDAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLT--AI 118
Cdd:PRK11228  33 ALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSALSPTPFAgySL 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 119 ALAAMLGGILTSLVVWAL--AWRNGIDTFRLIIIGIGIRAMLVAFNTWLLLKASlETALTAGLWNAGSLNGLTWAKTWPS 196
Cdd:PRK11228 113 AFIAACGGGLSWLLVMTAggGWRHTHDRNRLILAGIALSALCMALTRITLLLAE-DHAYGIFYWLAGGVSHARWQEVWQL 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 197 APLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTS-R 275
Cdd:PRK11228 192 LPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGYDqR 271

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 496059549 276 WGLTLSALCGALLLLMADLCAQQLFMPYQLPVGVVTVSLG 315
Cdd:PRK11228 272 NVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIG 311
btuC PRK09535
cobalamin ABC transporter permease BtuC;
46-323 9.99e-32

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 121.78  E-value: 9.99e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  46 DAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMLG 125
Cdd:PRK09535  82 AVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVPFGLQAAAFAG 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 126 GILTSLVVWALAWRNG-IDTFRLIIIGIGIRAMLVAFNTWLLLKA--SLETALtagLWNAGSLNGLTWAKTWPSAPLIII 202
Cdd:PRK09535 162 ALVAAFGVYAIATENGrTPVATLLLAGVAVQTFLGAVISYLLLHSgeSLRRAV---YWLMGHLHGSTWSDVEVALPVVVV 238

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 203 MLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTS-RWGLTLS 281
Cdd:PRK09535 239 GFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDhRILLPTS 318

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 496059549 282 ALCGALLLLMADLCAQQlfMPYQLPVGVVTVSLGGIYLIVLL 323
Cdd:PRK09535 319 ALAGASFLVATDTVARS--GPAEVPVGIVTAALGAPFFLYLL 358
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 53-328 3.89e-31

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 119.68  E-value: 3.89e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  53 LVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLT--AIALAAMLGGILTS 130
Cdd:PRK03784  52 LFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPpwALSLCAIAGALLIT 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 131 LVVWALAWRNGIDTFRLIIIGIGIRAMLVAFNTWLLLKASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIImLVCAALL 210
Cdd:PRK03784 132 LILLRFARRHRLSTSRLLLAGVALGIICSALMTWAVYFSTSLDLRQLMYWMMGGFGGVDWRQSWLMLALLPV-LIWLCCQ 210

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 211 VRRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTS-RWGLTLSALCGALLL 289
Cdd:PRK03784 211 GRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDhRVLLPGCALAGASLL 290

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 496059549 290 LMADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 328
Cdd:PRK03784 291 LLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHR 329
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
4-328 5.18e-29

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 114.03  E-value: 5.18e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   4 LSRRLIISSLLLVAGCLVIGLwSLRSGVVTLETQQIIAALLGDAPRSITLVVTEWRLPRVLMALLIGAALGVSGAIFQSL 83
Cdd:PRK10441   6 AVTRAIAVPGLLLLLIIATAL-SLLIGAKSLPASVVLEALSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  84 MRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALA-AMLGGILTSLVVWALAWRNG--IDTFRLIIIGIGIRAMLVA 160
Cdd:PRK10441  85 TRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAmAFAGALVASLIVAFTGSQGGgqLSPVRLTLAGVALAAVLEG 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 161 FNTWL-LLKASLETALTagLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLVRRMRLLEMGDDSACALGVSVERSRLMMM 239
Cdd:PRK10441 165 LTSGIaLLNPDVYDQLR--FWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 240 LVAVVLTAAATALAGPISFIALVAPHIARRISGTS-RWGLTLSALCGALLLLMADLcAQQLFMPYQLPVGVVTVSLGGIY 318
Cdd:PRK10441 243 LAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADhRWSLPVTLLATPALLLFADI-IGRLLVPGELRVSVVSAFIGAPV 321

                        330
                 ....*....|
gi 496059549 319 LIVLLIQESR 328
Cdd:PRK10441 322 LIFLVRRKTR 331
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 54-328 3.50e-28

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 111.49  E-value: 3.50e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549   54 VVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQhlTAIALAAMLGGILTSLVV 133
Cdd:TIGR03869  48 IVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVA--VLLPVAAFAGALLALAAT 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  134 WALAWRNGIDTFRLIIIGIGIRAMLVAFNTWLLL--KASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIIMLVCAALLV 211
Cdd:TIGR03869 126 LGLARTLGTLTPTRTILAGLAVSQLCAAVTSFVIfwSATGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASG 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  212 RRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTS-RWGLTLSALCGALLLL 290
Cdd:TIGR03869 206 RVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRhRLLLPVSALAGAVFLV 285

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 496059549  291 MADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 328
Cdd:TIGR03869 286 WADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
CeuC COG4605
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 59-329 4.56e-09

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443655  Cd Length: 317  Bit Score: 56.66  E-value: 4.56e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549  59 RLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTgAWSGVLVAMVLFGQHLTAIALAAMLGGILTSLVVWALAW 138
Cdd:COG4605   39 RGTKLAAMLLVAIAIAVSTVLFQTITNNRILTPSIMGFDS-LYVLIQTLLVFFLGSAGLAALNPLLNFLLEVALMVGFSL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 139 --------RNGIDTFRLIIIGIGIRAMLVAFNTWLLLK------ASLETALTAglwnagSLNGLTWAKTWPSAPLIIIML 204
Cdd:COG4605  118 llyrwlfrGGRRNLHLLLLVGVVLGTLFRSLSSFLQRLidpnefDVLQDRLFA------SFNNVNTDLLLIAAVIVLLAL 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496059549 205 VCAALLVRRMRLLEMGDDSACALGVSVERSRLMMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTSRWGLTL--SA 282
Cdd:COG4605  192 LLLWRLRRRLDVLALGRDQAINLGVDYRRVVRRLLILVAVLVAVSTALVGPITFLGLLVANLAYQLFGTYRHRYLLpaAA 271

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 496059549 283 LCGALLLLMADLCAQQLFMpYQLPVGVVTVSLGGIYLIVLLIQESRK 329
Cdd:COG4605  272 LIGVIALVGGQFVVEHVFN-FSTTLSVIIEFVGGIYFLYLLLRKRRL 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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