|
Name |
Accession |
Description |
Interval |
E-value |
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
17-690 |
0e+00 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 802.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 17 AYHSFLDA-KGLSPRAGQVDMMAfcsEVVNATPSEEQY--RVGVIEAGTGTGKTLGYCLPLIPLAMEKHKTLIISTATVA 93
Cdd:PRK11747 13 AYKALQEQlPGFIPRAGQRQMIA---EVAKTLAGEYLKdgRILVIEAGTGVGKTLSYLLAGIPIARAEKKKLVISTATVA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 94 LQEQIISKDLPEIQARAGLSFSYAMAKGRSRYFC----QMRCDVHmESEMNAYGYIRDDVEDIS-----------KAFAG 158
Cdd:PRK11747 90 LQEQLVSKDLPLLLKISGLDFKFTLAKGRGRYVCprklAALASDE-GTQQDLLLFLDDELTPPDeeeqkllarlaKALAT 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 159 GHWTGERDSYPDEISEAVWGRVNAIGSQCPKKRCPHYHRCPFFLARALLDSVDVVIANHDIVLSDLSLGGGIILPPQEES 238
Cdd:PRK11747 169 GKWDGDRDHWPEPIDDSLWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADLELGGGVVLPDPENL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 239 IYVFDEGHHVPQKAINHFATSASLDASRHFMAEIFDMV-------MTMPESYGGTMEQHVQQLVEfaghagnelgdlrgt 311
Cdd:PRK11747 249 LYVLDEGHHLPDVARDHFAASAELKGTADWLEKLLKLLtklvaliMEPPLALPERLNAHCEELRE--------------- 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 312 LLRSLNWRSDHDMPNGVESDIYRFPEGFVPEAIAALFSPALKTVNEMQNIVVKMTAIVDEAGRDISEDDLALQK--MAVG 389
Cdd:PRK11747 314 LLASLNQILNLFLPAGGEEARYRFEMGELPEELLELAERLAKLTEKLLGLLEKLLNDLSEAMKTGKIDIVRLERllLELG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 390 ELANRLAGMHQALASYCGNKTVSGMPMARWINVRRTKRSTEVVINCSPVYAGEHLKSELWSKAYATIVTSATIRSLSKFD 469
Cdd:PRK11747 394 RALGRLEALSKLWRLAAKEDQESGAPMARWITREERDGQGDYLFHASPIRVGDQLERLLWSRAPGAVLTSATLRSLNSFD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 470 AFLEQAGLPVD--TPTLLARSPFDYQNNGVLFIPRMRSVPTNHEEHTAEIIELLPKLVLRLQGCLVLFASRRQMEEVSKA 547
Cdd:PRK11747 474 RFQEQSGLPEKdgDRFLALPSPFDYPNQGKLVIPKMRAEPDNEEAHTAEMAEFLPELLEKHKGSLVLFASRRQMQKVADL 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 548 MPQHISPLLLIQGALPKREILLRHKLRIDRGEPSIIFGMASFSEGVDLPGVYCNNVIIAKLPFSVPTDPVGQTLTEWLEK 627
Cdd:PRK11747 554 LPRDLRLMLLVQGDQPRQRLLEKHKKRVDEGEGSVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAEWLKS 633
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 496062093 628 NGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKRLKTKAYGKDILASLPPFRREIR 690
Cdd:PRK11747 634 RGGNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIE 696
|
|
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
25-690 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 571.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 25 KGLSPRAGQVDMMAfcsEVVNATpseEQYRVGVIEAGTGTGKTLGYCLPLIPLAMEKHKTLIISTATVALQEQIISKDLP 104
Cdd:COG1199 11 PGFEPRPGQREMAE---AVARAL---AEGRHLLIEAGTGTGKTLAYLVPALLAARETGKKVVISTATKALQEQLVEKDLP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 105 EIQARAGLSFSYAMAKGRSRYFCQMRCDVHMESEmnAYGYIRDDVEDISKAFAGGHWTGERDSYPDEISEAVWGRVNAIG 184
Cdd:COG1199 85 LLRKALGLPLRVALLKGRSNYLCLRRLEQALQEG--DDLDDEELLLARILAWASETWTGDRDELPLPEDDELWRQVTSDA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 185 SQCPKKRCPHYHRCPFFLARALLDSVDVVIANHDIVLSDLSLGGGIiLPpqEESIYVFDEGHHVPQKAINHFATSASLDA 264
Cdd:COG1199 163 DNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALGEEL-LP--EDDVLIIDEAHNLPDRARDMFSAELSSRS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 265 SRHFMAEIFDMVMTMPesyggtmeqhVQQLVEFAGHAGNELGDLRGTLlrslnwrsdhdmpngVESDIYRFPEGFVPEAI 344
Cdd:COG1199 240 LLRLLRELRKLGLRPG----------LKKLLDLLERLREALDDLFLAL---------------EEEEELRLALGELPDEP 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 345 AALfspaLKTVNEMQNIVVKMTAIVDEAGRDISEddlalqkmaVGELANRLAGMHQALASYCgnKTVSGMPMARWInvrr 424
Cdd:COG1199 295 EEL----LEALDALRDALEALAEALEEELERLAE---------LDALLERLEELLFALARFL--RIAEDEGYVRWL---- 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 425 TKRSTEVVINCSPVYAGEHLKSELWSKAYATIVTSATIRSLSKFDAFLEQAGLPVDTPTLLARSPFDYQNNGVLFIPRMR 504
Cdd:COG1199 356 EREGGDVRLHAAPLDPADLLRELLFSRARSVVLTSATLSVGGPFDYFARRLGLDEDARTLSLPSPFDYENQALLYVPRDL 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 505 SVPTNHEEHTAEIIELLPKLVLRLQG-CLVLFASRRQMEEVSKAMPQHISPLLLIQGALPKREILLRHKlridRGEPSII 583
Cdd:COG1199 436 PRPSDRDGYLEAIAEAIAELLEASGGnTLVLFTSYRALEQVAELLRERLDIPVLVQGDGSREALLERFR----EGGNSVL 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 584 FGMASFSEGVDLPGVYCNNVIIAKLPFSVPTDPVGQTLTEWLEKNGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVT 663
Cdd:COG1199 512 VGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREALEARGGNGFMYAYLPPAVIKLKQGAGRLIRSEEDRGVVV 591
|
650 660
....*....|....*....|....*..
gi 496062093 664 ILDKRLKTKAYGKDILASLPPFRREIR 690
Cdd:COG1199 592 LLDRRLLTKRYGKRFLDSLPPFRRTRP 618
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
3-683 |
3.47e-58 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 211.20 E-value: 3.47e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 3 DNKPRMTAAEMTERAYHSFLDAKGLSPRAGQVDMMafcsEVVNATPSEEQyrVGVIEAGTGTGKTLGYCLPLIPLA-MEK 81
Cdd:TIGR01407 220 ASKKPETNYNTLSSLFSKNIDRLGLEYRPEQLKLA----ELVLDQLTHSE--KSLIEAPTGTGKTLGYLLPALYYAiTEK 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 82 HktLIISTATVALQEQIISKDLPEIQARAGLSFSYAMAKGRSRYFcQMRCDVH-MESEMNAYGYI--------------R 146
Cdd:TIGR01407 294 P--VVISTNTKVLQSQLLEKDIPLLNEILNFKINAALIKGKSNYL-SLGKFSQiLKDNTDNYEFNifkmqvlvwlteteT 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 147 DDVEDISKafagghwTGERDSYPDEISEAvwGRVNaigsqcpkKRCPHYHRCPFFLARALLDSVDVVIANHDIVLSDLSL 226
Cdd:TIGR01407 371 GDLDELNL-------KGGNKMFFAQVRHD--GNLS--------KKDLFYEVDFYNRAQKNAEQAQILITNHAYLITRLVD 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 227 GGGIIlppQEESIYVFDEGHHVPQKAINHfatsasldasrhfmaeifdmvmtmpesygGTMEQHVQQLVEFAGHAG-NEL 305
Cdd:TIGR01407 434 NPELF---PSFRDLIIDEAHHLPDIAENQ-----------------------------LQEELDYADIKYQIDLIGkGEN 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 306 GDLRGTLLRSLNWRSDHDMPNGVESDIyrfpegfvpeaiaalfspaLKTVNEMQNIVVKMTAIVDEAGRDI----SEDDL 381
Cdd:TIGR01407 482 EQLLKRIQQLEKQEILEKLFDFETKDI-------------------LKDLQAILDKLNKLLQIFSELSHKTvdqlRKFDL 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 382 ALQKMAVGeLANRLAGMHqalasycgnktvsgmpmARWINVRRTKRSTEVVINCSPVYAGEHLKSELWSKAYATIVTSAT 461
Cdd:TIGR01407 543 ALKDDFKN-IEQSLKEGH-----------------TSWISIENLQQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSAT 604
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 462 IRSLSKFDAFLEQAGLPVDTPTLLARSPFDYQNNGVLFIPRmrSVP----TNHEEHTAEIIELLPKLV-LRLQGCLVLFA 536
Cdd:TIGR01407 605 LKFSHSFESFPQLLGLTDVHFNTIEPTPLNYAENQRVLIPT--DAPaiqnKSLEEYAQEIASYIIEITaITSPKILVLFT 682
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 537 SRRQMEEVS---KAMPQHISPLLLIQGALPKREILLRhklRIDRGEPSIIFGMASFSEGVDLPGVYCNNVIIAKLPFSVP 613
Cdd:TIGR01407 683 SYEMLHMVYdmlNELPEFEGYEVLAQGINGSRAKIKK---RFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANP 759
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 614 TDPVGQTLTEWLEKNGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKRLKTKAYGKDILASLP 683
Cdd:TIGR01407 760 KHPLTKKYWQKLEQEGKNPFYDYVLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLP 829
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
530-685 |
6.04e-47 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 163.50 E-value: 6.04e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 530 GCLVLFASRRQMEEVSKAMPQHISPL---LLIQ-GALPKREILLRHKlriDRGEPSIIFGMA--SFSEGVDLPGVYCNNV 603
Cdd:pfam13307 10 GVLVFFPSYSYLEKVAERLKESGLEKgieIFVQpGEGSREKLLEEFK---KKGKGAVLFGVCggSFSEGIDFPGDLLRAV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 604 IIAKLPFSVPTDPVGQTLTEWLEKNGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKRLKTKAYGKDILASLP 683
Cdd:pfam13307 87 IIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLPKWLP 166
|
..
gi 496062093 684 PF 685
Cdd:pfam13307 167 PG 168
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
539-671 |
1.30e-23 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 96.96 E-value: 1.30e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 539 RQMEEVSKAMPQHISP----LLLIQGALPK-REILLRHKLRIDRGEPSIIFGMAS--FSEGVDLPGVYCNNVIIAKLPFS 611
Cdd:smart00491 2 RYLEQVVEYWKENGILeinkPVFIEGKDSGeTEELLEKYSAACEARGALLLAVARgkVSEGIDFPDDLGRAVIIVGIPFP 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496062093 612 VPTDPVGQTLTEWL-EKNGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKRLKT 671
Cdd:smart00491 82 NPDSPILRARLEYLdEKGGIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
590-668 |
5.79e-09 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 55.69 E-value: 5.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 590 SEGVDLPGVYCNNVIIAKLPFSVPTDPVGQ---TLTEWLEK----NGRDAFREisipEACLKLTQSVGRLIRTESDTGAV 662
Cdd:cd18788 77 SEGIDFSDDLGRAVIMVGIPYPNTKDPILKlkmDDLEYLRDkgllTGEDWYTF----QAMRAVNQAIGRAIRHKNDYGAI 152
|
....*.
gi 496062093 663 TILDKR 668
Cdd:cd18788 153 VLLDKR 158
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
17-690 |
0e+00 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 802.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 17 AYHSFLDA-KGLSPRAGQVDMMAfcsEVVNATPSEEQY--RVGVIEAGTGTGKTLGYCLPLIPLAMEKHKTLIISTATVA 93
Cdd:PRK11747 13 AYKALQEQlPGFIPRAGQRQMIA---EVAKTLAGEYLKdgRILVIEAGTGVGKTLSYLLAGIPIARAEKKKLVISTATVA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 94 LQEQIISKDLPEIQARAGLSFSYAMAKGRSRYFC----QMRCDVHmESEMNAYGYIRDDVEDIS-----------KAFAG 158
Cdd:PRK11747 90 LQEQLVSKDLPLLLKISGLDFKFTLAKGRGRYVCprklAALASDE-GTQQDLLLFLDDELTPPDeeeqkllarlaKALAT 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 159 GHWTGERDSYPDEISEAVWGRVNAIGSQCPKKRCPHYHRCPFFLARALLDSVDVVIANHDIVLSDLSLGGGIILPPQEES 238
Cdd:PRK11747 169 GKWDGDRDHWPEPIDDSLWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADLELGGGVVLPDPENL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 239 IYVFDEGHHVPQKAINHFATSASLDASRHFMAEIFDMV-------MTMPESYGGTMEQHVQQLVEfaghagnelgdlrgt 311
Cdd:PRK11747 249 LYVLDEGHHLPDVARDHFAASAELKGTADWLEKLLKLLtklvaliMEPPLALPERLNAHCEELRE--------------- 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 312 LLRSLNWRSDHDMPNGVESDIYRFPEGFVPEAIAALFSPALKTVNEMQNIVVKMTAIVDEAGRDISEDDLALQK--MAVG 389
Cdd:PRK11747 314 LLASLNQILNLFLPAGGEEARYRFEMGELPEELLELAERLAKLTEKLLGLLEKLLNDLSEAMKTGKIDIVRLERllLELG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 390 ELANRLAGMHQALASYCGNKTVSGMPMARWINVRRTKRSTEVVINCSPVYAGEHLKSELWSKAYATIVTSATIRSLSKFD 469
Cdd:PRK11747 394 RALGRLEALSKLWRLAAKEDQESGAPMARWITREERDGQGDYLFHASPIRVGDQLERLLWSRAPGAVLTSATLRSLNSFD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 470 AFLEQAGLPVD--TPTLLARSPFDYQNNGVLFIPRMRSVPTNHEEHTAEIIELLPKLVLRLQGCLVLFASRRQMEEVSKA 547
Cdd:PRK11747 474 RFQEQSGLPEKdgDRFLALPSPFDYPNQGKLVIPKMRAEPDNEEAHTAEMAEFLPELLEKHKGSLVLFASRRQMQKVADL 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 548 MPQHISPLLLIQGALPKREILLRHKLRIDRGEPSIIFGMASFSEGVDLPGVYCNNVIIAKLPFSVPTDPVGQTLTEWLEK 627
Cdd:PRK11747 554 LPRDLRLMLLVQGDQPRQRLLEKHKKRVDEGEGSVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAEWLKS 633
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 496062093 628 NGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKRLKTKAYGKDILASLPPFRREIR 690
Cdd:PRK11747 634 RGGNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIE 696
|
|
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
25-690 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 571.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 25 KGLSPRAGQVDMMAfcsEVVNATpseEQYRVGVIEAGTGTGKTLGYCLPLIPLAMEKHKTLIISTATVALQEQIISKDLP 104
Cdd:COG1199 11 PGFEPRPGQREMAE---AVARAL---AEGRHLLIEAGTGTGKTLAYLVPALLAARETGKKVVISTATKALQEQLVEKDLP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 105 EIQARAGLSFSYAMAKGRSRYFCQMRCDVHMESEmnAYGYIRDDVEDISKAFAGGHWTGERDSYPDEISEAVWGRVNAIG 184
Cdd:COG1199 85 LLRKALGLPLRVALLKGRSNYLCLRRLEQALQEG--DDLDDEELLLARILAWASETWTGDRDELPLPEDDELWRQVTSDA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 185 SQCPKKRCPHYHRCPFFLARALLDSVDVVIANHDIVLSDLSLGGGIiLPpqEESIYVFDEGHHVPQKAINHFATSASLDA 264
Cdd:COG1199 163 DNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALGEEL-LP--EDDVLIIDEAHNLPDRARDMFSAELSSRS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 265 SRHFMAEIFDMVMTMPesyggtmeqhVQQLVEFAGHAGNELGDLRGTLlrslnwrsdhdmpngVESDIYRFPEGFVPEAI 344
Cdd:COG1199 240 LLRLLRELRKLGLRPG----------LKKLLDLLERLREALDDLFLAL---------------EEEEELRLALGELPDEP 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 345 AALfspaLKTVNEMQNIVVKMTAIVDEAGRDISEddlalqkmaVGELANRLAGMHQALASYCgnKTVSGMPMARWInvrr 424
Cdd:COG1199 295 EEL----LEALDALRDALEALAEALEEELERLAE---------LDALLERLEELLFALARFL--RIAEDEGYVRWL---- 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 425 TKRSTEVVINCSPVYAGEHLKSELWSKAYATIVTSATIRSLSKFDAFLEQAGLPVDTPTLLARSPFDYQNNGVLFIPRMR 504
Cdd:COG1199 356 EREGGDVRLHAAPLDPADLLRELLFSRARSVVLTSATLSVGGPFDYFARRLGLDEDARTLSLPSPFDYENQALLYVPRDL 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 505 SVPTNHEEHTAEIIELLPKLVLRLQG-CLVLFASRRQMEEVSKAMPQHISPLLLIQGALPKREILLRHKlridRGEPSII 583
Cdd:COG1199 436 PRPSDRDGYLEAIAEAIAELLEASGGnTLVLFTSYRALEQVAELLRERLDIPVLVQGDGSREALLERFR----EGGNSVL 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 584 FGMASFSEGVDLPGVYCNNVIIAKLPFSVPTDPVGQTLTEWLEKNGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVT 663
Cdd:COG1199 512 VGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREALEARGGNGFMYAYLPPAVIKLKQGAGRLIRSEEDRGVVV 591
|
650 660
....*....|....*....|....*..
gi 496062093 664 ILDKRLKTKAYGKDILASLPPFRREIR 690
Cdd:COG1199 592 LLDRRLLTKRYGKRFLDSLPPFRRTRP 618
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
26-684 |
2.85e-82 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 279.53 E-value: 2.85e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 26 GLSPRAGQVDMMafcsEVVNATPSEEQYrvGVIEAGTGTGKTLGYCLPLIPLAMEKHKTLIISTATVALQEQIISKDLPE 105
Cdd:PRK08074 255 KYEKREGQQEMM----KEVYTALRDSEH--ALIEAGTGTGKSLAYLLPAAYFAKKKEEPVVISTYTIQLQQQLLEKDIPL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 106 IQARAGLSFSYAMAKGRSRYFCQMRCDVHMESEmnaygyirDDVEDISKAFAGGH-W-----TGERDsypdEIS-----E 174
Cdd:PRK08074 329 LQKIFPFPVEAALLKGRSHYLCLRKFEQALQEE--------DDNYDVALTKAQLLvWlteteTGDLD----ELNlpsggK 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 175 AVWGRVNAIGSQCPKKRCPHYHRCPFFLARALLDSVDVVIANHDIVLSDLSlGGGIILPPQEEsiYVFDEGHHVPQKAIN 254
Cdd:PRK08074 397 LLWNRIASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLT-SEEPLLPSYEH--IIIDEAHHFEEAASR 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 255 HFATSASLDASRHFMAEI--------FDMVMTMPESYGGTMEQHVQQLVEFAGHAGNELGDLrgtlLRSLNWRSDHDMPN 326
Cdd:PRK08074 474 HLGEQFSYMSFQLLLSRLgtleedglLSKLAKLFKKSDQASRSSFRDLDESLKELKFEADEL----FQMLRSFVLKRKKQ 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 327 gveSDIYRFPEGFVPEAI-AALFSPALKTVNEMQNIVVKMTAIVDEAGRDISEDDLALQKMAVGELANRLAGMHQALASY 405
Cdd:PRK08074 550 ---EQNGRLIYRYNTESEkGKLWDAITELANRLCYDLRDLLTLLEAQKKELQEKMESESAFLTGEYAHLIDLLEKMAQLL 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 406 -----CGNKTVsgmpmaRWINV--RRTKRSTevVINCSPVYAGEHLKSELWSKAYATIVTSATIRSLSKFDAFLEQAGLP 478
Cdd:PRK08074 627 qllfeEDPDYV------TWIEIdaKGAINAT--RLYAQPVEVAERLADEFFAKKKSVILTSATLTVNGSFDYIIERLGLE 698
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 479 VDTP-TLLARSPFDYQNNGVLFIPR-MRSVP-TNHEEHTAEIIELLPKLVLRLQG-CLVLFASRRQMEEVSKAMPQH--I 552
Cdd:PRK08074 699 DFYPrTLQIPSPFSYEEQAKLMIPTdMPPIKdVPIEEYIEEVAAYIAKIAKATKGrMLVLFTSYEMLKKTYYNLKNEeeL 778
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 553 SPLLL----IQGALPKReiLLRHKLRIDRgepSIIFGMASFSEGVDLPGVYCNNVIIAKLPFSVPTDPVGQTLTEWLEKN 628
Cdd:PRK08074 779 EGYVLlaqgVSSGSRAR--LTKQFQQFDK---AILLGTSSFWEGIDIPGDELSCLVIVRLPFAPPDQPVMEAKSEWAKEQ 853
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*.
gi 496062093 629 GRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKRLKTKAYGKDILASLPP 684
Cdd:PRK08074 854 GENPFQELSLPQAVLRFKQGFGRLIRTETDRGTVFVLDRRLTTTSYGKYFLESLPT 909
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
3-683 |
3.47e-58 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 211.20 E-value: 3.47e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 3 DNKPRMTAAEMTERAYHSFLDAKGLSPRAGQVDMMafcsEVVNATPSEEQyrVGVIEAGTGTGKTLGYCLPLIPLA-MEK 81
Cdd:TIGR01407 220 ASKKPETNYNTLSSLFSKNIDRLGLEYRPEQLKLA----ELVLDQLTHSE--KSLIEAPTGTGKTLGYLLPALYYAiTEK 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 82 HktLIISTATVALQEQIISKDLPEIQARAGLSFSYAMAKGRSRYFcQMRCDVH-MESEMNAYGYI--------------R 146
Cdd:TIGR01407 294 P--VVISTNTKVLQSQLLEKDIPLLNEILNFKINAALIKGKSNYL-SLGKFSQiLKDNTDNYEFNifkmqvlvwlteteT 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 147 DDVEDISKafagghwTGERDSYPDEISEAvwGRVNaigsqcpkKRCPHYHRCPFFLARALLDSVDVVIANHDIVLSDLSL 226
Cdd:TIGR01407 371 GDLDELNL-------KGGNKMFFAQVRHD--GNLS--------KKDLFYEVDFYNRAQKNAEQAQILITNHAYLITRLVD 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 227 GGGIIlppQEESIYVFDEGHHVPQKAINHfatsasldasrhfmaeifdmvmtmpesygGTMEQHVQQLVEFAGHAG-NEL 305
Cdd:TIGR01407 434 NPELF---PSFRDLIIDEAHHLPDIAENQ-----------------------------LQEELDYADIKYQIDLIGkGEN 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 306 GDLRGTLLRSLNWRSDHDMPNGVESDIyrfpegfvpeaiaalfspaLKTVNEMQNIVVKMTAIVDEAGRDI----SEDDL 381
Cdd:TIGR01407 482 EQLLKRIQQLEKQEILEKLFDFETKDI-------------------LKDLQAILDKLNKLLQIFSELSHKTvdqlRKFDL 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 382 ALQKMAVGeLANRLAGMHqalasycgnktvsgmpmARWINVRRTKRSTEVVINCSPVYAGEHLKSELWSKAYATIVTSAT 461
Cdd:TIGR01407 543 ALKDDFKN-IEQSLKEGH-----------------TSWISIENLQQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSAT 604
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 462 IRSLSKFDAFLEQAGLPVDTPTLLARSPFDYQNNGVLFIPRmrSVP----TNHEEHTAEIIELLPKLV-LRLQGCLVLFA 536
Cdd:TIGR01407 605 LKFSHSFESFPQLLGLTDVHFNTIEPTPLNYAENQRVLIPT--DAPaiqnKSLEEYAQEIASYIIEITaITSPKILVLFT 682
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 537 SRRQMEEVS---KAMPQHISPLLLIQGALPKREILLRhklRIDRGEPSIIFGMASFSEGVDLPGVYCNNVIIAKLPFSVP 613
Cdd:TIGR01407 683 SYEMLHMVYdmlNELPEFEGYEVLAQGINGSRAKIKK---RFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANP 759
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 614 TDPVGQTLTEWLEKNGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKRLKTKAYGKDILASLP 683
Cdd:TIGR01407 760 KHPLTKKYWQKLEQEGKNPFYDYVLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLP 829
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
530-685 |
6.04e-47 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 163.50 E-value: 6.04e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 530 GCLVLFASRRQMEEVSKAMPQHISPL---LLIQ-GALPKREILLRHKlriDRGEPSIIFGMA--SFSEGVDLPGVYCNNV 603
Cdd:pfam13307 10 GVLVFFPSYSYLEKVAERLKESGLEKgieIFVQpGEGSREKLLEEFK---KKGKGAVLFGVCggSFSEGIDFPGDLLRAV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 604 IIAKLPFSVPTDPVGQTLTEWLEKNGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKRLKTKAYGKDILASLP 683
Cdd:pfam13307 87 IIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLPKWLP 166
|
..
gi 496062093 684 PF 685
Cdd:pfam13307 167 PG 168
|
|
| PRK07246 |
PRK07246 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
511-682 |
2.99e-27 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 180905 [Multi-domain] Cd Length: 820 Bit Score: 117.87 E-value: 2.99e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 511 EEHTAEIIELLPKLVLRLQGCLVLFASRRQMEEVSKAMPQ-HISPLlliqgALPKREILLRHKLRIDRGEPSIIFGMASF 589
Cdd:PRK07246 630 EVYAEEIAKRLEELKQLQQPILVLFNSKKHLLAVSDLLDQwQVSHL-----AQEKNGTAYNIKKRFDRGEQQILLGLGSF 704
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 590 SEGVDLpgVYCNNVI--IAKLPFSVPTDPVGQTLTEWLEKNGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDK 667
Cdd:PRK07246 705 WEGVDF--VQADRMIevITRLPFDNPEDPFVKKMNQYLLQEGKNPFYDYFLPMTILRLKQAIGRTMRREDQKSAVLILDR 782
|
170
....*....|....*
gi 496062093 668 RLKTKAYGKDILASL 682
Cdd:PRK07246 783 RILTKSYGKQILASL 797
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
539-671 |
1.30e-23 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 96.96 E-value: 1.30e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 539 RQMEEVSKAMPQHISP----LLLIQGALPK-REILLRHKLRIDRGEPSIIFGMAS--FSEGVDLPGVYCNNVIIAKLPFS 611
Cdd:smart00491 2 RYLEQVVEYWKENGILeinkPVFIEGKDSGeTEELLEKYSAACEARGALLLAVARgkVSEGIDFPDDLGRAVIIVGIPFP 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496062093 612 VPTDPVGQTLTEWL-EKNGRDAFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKRLKT 671
Cdd:smart00491 82 NPDSPILRARLEYLdEKGGIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| rad3 |
TIGR00604 |
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are ... |
197-668 |
7.42e-15 |
|
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are DNA-DNA helicases that funciton in the initiation of transcription and nucleotide excision repair as part of the TFIIH complex. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273169 [Multi-domain] Cd Length: 705 Bit Score: 78.22 E-value: 7.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 197 RCPFFLARALLDSVDVVIANHDIVLSD-------LSLgggiilppqEESIYVFDEGHHVPQKAINHFA---TSASLDASR 266
Cdd:TIGR00604 183 LCPYFATRKMLPFANIVLLPYQYLLDPkirsavsIEL---------KDSIVIFDEAHNLDNVCISSLSsnlSVRSLKRCS 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 267 HFMAEIFDMVMTMPESYGGTMEQHVQQLVEFaghagnelgdlrgtlLRSLNwrSDHDMPNGVESDIYrfPEGFVPEAIAA 346
Cdd:TIGR00604 254 KEIAEYFEKIEERKEVDARKLLDELQKLVEG---------------LKQED--LLTDEDIFLANPVL--PKEVLPEAVPG 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 347 LFSPA------LKTVNEMQNIVVKMTAIVDEAGRDISEDDLALQKMA--VGELANRLAGMHQALASYCGNKTVSGMPMAR 418
Cdd:TIGR00604 315 NIRIAeiflhkLSRYLEYLKDALKVLGVVSELPDAFLEHLKEKTFIDrpLRFCSERLSNLLRELEITHPEDFSALVLLFT 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 419 WINVRRTKRSTeVVINCSPVY---------------AGEHLKsELWSKAYATIVTSATirsLSKFDAFLEQAGLPV---D 480
Cdd:TIGR00604 395 FATLVLTYTNG-FLEGIEPYEnktvpnpilkfmcldPSIALK-PLFERVRSVILASGT---LSPLDAFPRNLGFNPvsqD 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 481 TPT-LLARSPF-----DYQNNGVLF-----IPRMRSVPTNHEEHTAEIIELLPklvlrlQGCLVLFASRRQMEEVSKAMp 549
Cdd:TIGR00604 470 SPThILKRENLltlivTRGSDQVPLsstfeIRNDPSLVRNLGELLVEFSKIIP------DGIVVFFPSYSYLENIVSTW- 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 550 QHI--------SPLLLI--QGALPKREILLRHKLRIDRGEPSIIFGMA--SFSEGVDLPGVYCNNVIIAKLPFSVPTDPV 617
Cdd:TIGR00604 543 KEMgileniekKKLIFVetKDAQETSDALERYKQAVSEGRGAVLLSVAggKVSEGIDFCDDLGRAVIMVGIPYEYTESRI 622
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 496062093 618 GQTLTEWLEKNGRD-AFREISIPEACLKLTQSVGRLIRTESDTGAVTILDKR 668
Cdd:TIGR00604 623 LLARLEFLRDQYPIrENQDFYEFDAMRAVNQAIGRVIRHKDDYGSIVLLDKR 674
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
590-668 |
5.79e-09 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 55.69 E-value: 5.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 590 SEGVDLPGVYCNNVIIAKLPFSVPTDPVGQ---TLTEWLEK----NGRDAFREisipEACLKLTQSVGRLIRTESDTGAV 662
Cdd:cd18788 77 SEGIDFSDDLGRAVIMVGIPYPNTKDPILKlkmDDLEYLRDkgllTGEDWYTF----QAMRAVNQAIGRAIRHKNDYGAI 152
|
....*.
gi 496062093 663 TILDKR 668
Cdd:cd18788 153 VLLDKR 158
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
508-666 |
5.00e-04 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 43.09 E-value: 5.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 508 TNHEEHTAEII-ELLPKLVLRLQGcLVLFASRRQMEEVSKAMPQHISPLLLIQGALPKREillRHKL--RIDRGEPSIIF 584
Cdd:COG1061 285 AADAERKDKILrELLREHPDDRKT-LVFCSSVDHAEALAELLNEAGIRAAVVTGDTPKKE---REEIleAFRDGELRILV 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496062093 585 GMASFSEGVDLPGVYCnnVIIAKlpfsvPTdpvgQTLTEWLekngrdafreisipeaclkltQSVGRLIRTESDTGAVTI 664
Cdd:COG1061 361 TVDVLNEGVDVPRLDV--AILLR-----PT----GSPREFI---------------------QRLGRGLRPAPGKEDALV 408
|
..
gi 496062093 665 LD 666
Cdd:COG1061 409 YD 410
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
50-98 |
5.20e-04 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 41.71 E-value: 5.20e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 496062093 50 EEQYRVGVIEAGTGTGKTLGYCLPLIPLAMEKH--KTLIIStATVALQEQI 98
Cdd:smart00487 21 LSGLRDVILAAPTGSGKTLAALLPALEALKRGKggRVLVLV-PTRELAEQW 70
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
57-98 |
1.49e-03 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 39.92 E-value: 1.49e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 496062093 57 VIEAGTGTGKTLGYCLPL---IPLAMEKHKTLIISTaTVALQEQI 98
Cdd:pfam00270 18 LVQAPTGSGKTLAFLLPAleaLDKLDNGPQALVLAP-TRELAEQI 61
|
|
| DEAD_2 |
pfam06733 |
DEAD_2; This represents a conserved region within a number of RAD3-like DNA-binding helicases ... |
196-267 |
2.54e-03 |
|
DEAD_2; This represents a conserved region within a number of RAD3-like DNA-binding helicases that are seemingly ubiquitous - members include proteins of eukaryotic, bacterial and archaeal origin. RAD3 is involved in nucleotide excision repair, and forms part of the transcription factor TFIIH in yeast.
Pssm-ID: 399602 [Multi-domain] Cd Length: 168 Bit Score: 39.17 E-value: 2.54e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 496062093 196 HRCPFFLARALLDSVDVVIANHDIVLS-------DLSLgggiilppqEESIYVFDEGHHVpqkaINHFATSASLDASRH 267
Cdd:pfam06733 101 GICPYYLSRELIPDADIIILPYNYLLDpkireslSINL---------KNSIVIFDEAHNI----EDVCIESASFSISRS 166
|
|
| |
