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Conserved domains on  [gi|496083293|ref|WP_008807800|]
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MULTISPECIES: ABC transporter permease [Klebsiella]

Protein Classification

ABC transporter permease( domain architecture ID 11467993)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter, which may be involved in the transport of one or more from a variety of substrates such as nopaline and octopine

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArtQ COG4215
ABC-type arginine transport system, permease component [Amino acid transport and metabolism];
1-236 6.07e-93

ABC-type arginine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 443361 [Multi-domain]  Cd Length: 238  Bit Score: 272.77  E-value: 6.07e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293   1 MLNLLSFGENGWGTLILSATLTTLLLSLAALAVGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGS 80
Cdd:COG4215    3 MLTLLMFGLQGWGPALLAGALVTLELALLSLLLGLVLGLLGALAKLSGNRPLRWLATGYTTVVRGVPDLLLILLLYFGGQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  81 GMISWVGRLFGADGFIEVPPFLIGALAIGLISSSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLP 160
Cdd:COG4215   83 ILLNALADLFGYDGFIEINPFVAGVLALGFVFGAYATEVFRGAFLAVPKGQIEAARAYGMSRWQVFRRILLPQMWRYALP 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496083293 161 GLSNVWQMSLKDSALVSVTGIVELMRASQIAAGSTRDYFLFYLIGGGCYLILTLLSNRAFTRAESHLNRAWLRRSA 236
Cdd:COG4215  163 GLGNNWLVLLKDTALVSVIGLVDLVRQAQEAAGSTREPFTFYLAAALIYLALTTVSELVLARLERRASRGVRRAAG 238
 
Name Accession Description Interval E-value
ArtQ COG4215
ABC-type arginine transport system, permease component [Amino acid transport and metabolism];
1-236 6.07e-93

ABC-type arginine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443361 [Multi-domain]  Cd Length: 238  Bit Score: 272.77  E-value: 6.07e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293   1 MLNLLSFGENGWGTLILSATLTTLLLSLAALAVGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGS 80
Cdd:COG4215    3 MLTLLMFGLQGWGPALLAGALVTLELALLSLLLGLVLGLLGALAKLSGNRPLRWLATGYTTVVRGVPDLLLILLLYFGGQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  81 GMISWVGRLFGADGFIEVPPFLIGALAIGLISSSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLP 160
Cdd:COG4215   83 ILLNALADLFGYDGFIEINPFVAGVLALGFVFGAYATEVFRGAFLAVPKGQIEAARAYGMSRWQVFRRILLPQMWRYALP 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496083293 161 GLSNVWQMSLKDSALVSVTGIVELMRASQIAAGSTRDYFLFYLIGGGCYLILTLLSNRAFTRAESHLNRAWLRRSA 236
Cdd:COG4215  163 GLGNNWLVLLKDTALVSVIGLVDLVRQAQEAAGSTREPFTFYLAAALIYLALTTVSELVLARLERRASRGVRRAAG 238
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
40-229 3.39e-40

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 138.27  E-value: 3.39e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  40 VIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGS------------GMISWVGRLFGADGFIEVPPFLIGALA 107
Cdd:PRK11123  31 LFAVWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGSSqllltlsdgftlNLGFVQIPVQMDIENFEVSPFLCGVIA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 108 IGLISSSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRA 187
Cdd:PRK11123 111 LSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQWLVLLKDTALVSLISVNDLMLQ 190

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 496083293 188 SQIAAGSTRDYFLFYLIGGGCYLILTLLSNRAFTRAESHLNR 229
Cdd:PRK11123 191 TKSIATRTQEPFTWYIIAAAIYLVITLISQYILKRIELRATR 232
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 33-227 5.52e-17

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 76.43  E-value: 5.52e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293   33 VGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFggsgmiswVGRLFGadgfIEVPPFLIGALAIGLIS 112
Cdd:TIGR03003  30 IAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYY--------VLPDIG----IRLPALVAGVLGLGLHY 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  113 SSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAA 192
Cdd:TIGR03003  98 ATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFKETPVLSAITVLELMNQAKSIG 177

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 496083293  193 GSTRDYFLFYLIGGGCYLILTLLSNRAFTRAESHL 227
Cdd:TIGR03003 178 NSTFRYLEPMTLVGVFFLILSIISVFFLRRLEARL 212
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 33-215 5.26e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.90  E-value: 5.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  33 VGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGSGMISWVGRLFgadgfievpPFLIGALAIGLIS 112
Cdd:cd06261   14 LALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPG---------LGLPALILALLLI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 113 SSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAA 192
Cdd:cd06261   85 APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGLL 164

                        170       180
                 ....*....|....*....|...
gi 496083293 193 GSTRDYFLFYLIGGGCYLILTLL 215
Cdd:cd06261  165 LIFAILFPGDLGVAAAVALILLL 187
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 35-221 9.92e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 44.60  E-value: 9.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293   35 AGVGGVIAAAKLSRhaPARWFGAAWSVVFRGIPELLVIYLFYFGGsgMISWVGRLFgadgfievppfLIGALAIGLISSS 114
Cdd:pfam00528   1 GIPLGIIAALRRGR--RLDRLLRPLIDLLQALPSFVLAILLVVIA--ILSILGHGI-----------LPAIILALLGWAG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  115 YQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAAGS 194
Cdd:pfam00528  66 YARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAIL 145

                         170       180       190
                  ....*....|....*....|....*....|
gi 496083293  195 TRDYFL---FYLIGGGCYLILTLLSNRAFT 221
Cdd:pfam00528 146 GYDYPEiqgPVLAAALILLLLNLLVDILQR 175
 
Name Accession Description Interval E-value
ArtQ COG4215
ABC-type arginine transport system, permease component [Amino acid transport and metabolism];
1-236 6.07e-93

ABC-type arginine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443361 [Multi-domain]  Cd Length: 238  Bit Score: 272.77  E-value: 6.07e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293   1 MLNLLSFGENGWGTLILSATLTTLLLSLAALAVGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGS 80
Cdd:COG4215    3 MLTLLMFGLQGWGPALLAGALVTLELALLSLLLGLVLGLLGALAKLSGNRPLRWLATGYTTVVRGVPDLLLILLLYFGGQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  81 GMISWVGRLFGADGFIEVPPFLIGALAIGLISSSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLP 160
Cdd:COG4215   83 ILLNALADLFGYDGFIEINPFVAGVLALGFVFGAYATEVFRGAFLAVPKGQIEAARAYGMSRWQVFRRILLPQMWRYALP 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496083293 161 GLSNVWQMSLKDSALVSVTGIVELMRASQIAAGSTRDYFLFYLIGGGCYLILTLLSNRAFTRAESHLNRAWLRRSA 236
Cdd:COG4215  163 GLGNNWLVLLKDTALVSVIGLVDLVRQAQEAAGSTREPFTFYLAAALIYLALTTVSELVLARLERRASRGVRRAAG 238
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 33-230 4.78e-46

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 152.54  E-value: 4.78e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  33 VGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGSGMiswvgrlfgadgFIEVPPFLIGALAIGLIS 112
Cdd:COG0765   32 LGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL------------GIDLSPFVAAVIALTLNS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 113 SSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAA 192
Cdd:COG0765  100 AAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLKDTSLVSVIGVPELTRAAQQIA 179

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 496083293 193 GSTRDYFLFYLIGGGCYLILTLLSNRAFTRAESHLNRA 230
Cdd:COG0765  180 SRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRLARG 217
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
40-229 3.39e-40

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 138.27  E-value: 3.39e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  40 VIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGS------------GMISWVGRLFGADGFIEVPPFLIGALA 107
Cdd:PRK11123  31 LFAVWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGSSqllltlsdgftlNLGFVQIPVQMDIENFEVSPFLCGVIA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 108 IGLISSSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRA 187
Cdd:PRK11123 111 LSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQWLVLLKDTALVSLISVNDLMLQ 190

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 496083293 188 SQIAAGSTRDYFLFYLIGGGCYLILTLLSNRAFTRAESHLNR 229
Cdd:PRK11123 191 TKSIATRTQEPFTWYIIAAAIYLVITLISQYILKRIELRATR 232
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
37-217 1.96e-31

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 115.28  E-value: 1.96e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  37 VGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGSGMISWVGRLFGADGfIEVPPFLIGALAIGLISSSYQ 116
Cdd:PRK15135  30 IGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVTEALGVGQ-IDIDPMVAGIITLGFIYGAYF 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 117 AEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAAGSTR 196
Cdd:PRK15135 109 TETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQVILKATALVSLLGLEDVVKATQLAGKSTW 188

                        170       180
                 ....*....|....*....|.
gi 496083293 197 DYFLFYLIGGGCYLILTLLSN 217
Cdd:PRK15135 189 EPFYFAIVCGVIYLVFTTVSN 209
PRK15100 PRK15100
cystine ABC transporter permease;
33-229 7.35e-24

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 95.20  E-value: 7.35e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  33 VGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGSGmiswvgrlFGadgfIEVPPFLIGALAIGLIS 112
Cdd:PRK15100  32 FGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQ--------FG----IELDPIPAAMIGLSLNT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 113 SSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAA 192
Cdd:PRK15100 100 AAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATIQVPELFRQAQLIT 179

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 496083293 193 GSTRDYFLFYLIGGGCYLILTLLSNRAFTRAESHLNR 229
Cdd:PRK15100 180 SRTLEVFTMYLAASLIYWIMATVLSALQNRFENQLNR 216
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 33-227 5.52e-17

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 76.43  E-value: 5.52e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293   33 VGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFggsgmiswVGRLFGadgfIEVPPFLIGALAIGLIS 112
Cdd:TIGR03003  30 IAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYY--------VLPDIG----IRLPALVAGVLGLGLHY 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  113 SSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAA 192
Cdd:TIGR03003  98 ATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFKETPVLSAITVLELMNQAKSIG 177

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 496083293  193 GSTRDYFLFYLIGGGCYLILTLLSNRAFTRAESHL 227
Cdd:TIGR03003 178 NSTFRYLEPMTLVGVFFLILSIISVFFLRRLEARL 212
ectoine_ehuC TIGR03004
ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are ...
 45-229 2.39e-15

ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons. Permease subunits EhuC and EhuD are homologous.


Pssm-ID: 132049 [Multi-domain]  Cd Length: 214  Bit Score: 72.19  E-value: 2.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293   45 KLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFggsgmiswVGRLFGadgfIEVPPFLIGALAIGLISSSYQAEVYRAAR 124
Cdd:TIGR03004  36 RVSGGPILRTVALCYIEVFRGTSLLVQLFWFYF--------VLPLIG----LSLDPVTTGVMVLGLHAGAYGAEIVRGAL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  125 LALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAAGSTRDYFLFYLI 204
Cdd:TIGR03004 104 SSVSVQQLEACRALNFTRFQTLRRISLPQALVEMMPAFGNLAIELLKLTSLVSLISLADLTFAAQSIRNLTLDTLSIFAI 183

                         170       180
                  ....*....|....*....|....*
gi 496083293  205 GGGCYLILTLLSNRAFTRAESHLNR 229
Cdd:TIGR03004 184 TLLCYFVMALIIMLIMRVLERVVRR 208
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 52-227 4.51e-13

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 65.85  E-value: 4.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  52 ARWFGAAWS--------VVFRGIPELLVIYLFYFGGSGMISWVgrlfgadgfiEVPPFLIGALAIGLISSSYQAEVYRAA 123
Cdd:PRK09494  43 ARAYGGWIAnhialvfiELIRGTPIVVQVMFIYFALPMAFNDL----------RIDPFTAAVVTIMINSGAYIAEITRGA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 124 RLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQ-IAAGSTRDYFLFY 202
Cdd:PRK09494 113 VLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLGNQWIISIKDTSLFIVIGVAELTRQGQeIIAGNFRALEIWS 192

                        170       180
                 ....*....|....*....|....*
gi 496083293 203 LIgGGCYLILTLLSNRAFTRAESHL 227
Cdd:PRK09494 193 AV-AVIYLIITLVLSFILRRLERRM 216
PRK15069 PRK15069
histidine ABC transporter permease HisM;
36-233 2.12e-11

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 61.60  E-value: 2.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  36 GVGGV----IAAAKLSRHAPARWFGAAWSVVFRGIP---ELLVIYlfyfggSGMISWvgrlfgadGFIEVPPFL------ 102
Cdd:PRK15069  35 VIGFVlavpLAIARVSSNKWIRFPVWLYTYVFRGTPlyvQLLVFY------TGMYSL--------EIVRGTDLLdaffrs 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 103 ---IGALAIGLISSSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVT 179
Cdd:PRK15069 101 glnCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTLAFTA 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 496083293 180 GIVELMRASQIAAGSTRDYFLFYLIGGGCYLILTLLSNRAFTRAEshlnRAWLR 233
Cdd:PRK15069 181 TVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAE----RRWLA 230
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
33-214 1.29e-10

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 59.46  E-value: 1.29e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  33 VGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGSGMISwvgRLFGADGFIEVPpfLIGAL-AIGLI 111
Cdd:PRK15107  33 IGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQ---NVLGLSPKTDIR--LISAMvAFSMF 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 112 SSSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIA 191
Cdd:PRK15107 108 EAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADFFRTASTI 187

                        170       180
                 ....*....|....*....|...
gi 496083293 192 AGSTRDYFLFYLIGGGCYLILTL 214
Cdd:PRK15107 188 GERDGTQVEMILFAGFVYFVISL 210
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 33-215 5.26e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.90  E-value: 5.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  33 VGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGSGMISWVGRLFgadgfievpPFLIGALAIGLIS 112
Cdd:cd06261   14 LALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPG---------LGLPALILALLLI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 113 SSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAA 192
Cdd:cd06261   85 APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGLL 164

                        170       180
                 ....*....|....*....|...
gi 496083293 193 GSTRDYFLFYLIGGGCYLILTLL 215
Cdd:cd06261  165 LIFAILFPGDLGVAAAVALILLL 187
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 33-122 1.24e-09

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 53.69  E-value: 1.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293   33 VGAGVGGVIAAAKLSRHAPARWFGAAWSVVFRGIPELLVIYLFYFGGSgmiswvgrLFGadgfIEVPPFLIGALAIGLIS 112
Cdd:TIGR01726  22 LGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLP--------LIG----IRLSPLTAAVIALTLFY 89

                          90
                  ....*....|
gi 496083293  113 SSYQAEVYRA 122
Cdd:TIGR01726  90 GAYLAEIFRG 99
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 33-164 6.43e-06

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 46.29  E-value: 6.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  33 VGAGVGGVIAAAKLSRHAPARWF--GAAWSVVFRGIPELLVIYLFYFGGSGM-ISW---VGRLFGADGFIEVPPFLIgAL 106
Cdd:COG4597  190 LAALLAAIVAAFVLRRWARRRQEatGQRFPVWWISLALLVGLPLLAFLLLGApLSLdypELKGFNFRGGLTLSPEFV-AL 268

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293 107 AIGLI--SSSYQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSN 164
Cdd:COG4597  269 LLALSlyTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIPPLTS 328
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 35-221 9.92e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 44.60  E-value: 9.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293   35 AGVGGVIAAAKLSRhaPARWFGAAWSVVFRGIPELLVIYLFYFGGsgMISWVGRLFgadgfievppfLIGALAIGLISSS 114
Cdd:pfam00528   1 GIPLGIIAALRRGR--RLDRLLRPLIDLLQALPSFVLAILLVVIA--ILSILGHGI-----------LPAIILALLGWAG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496083293  115 YQAEVYRAARLALMPGEVEAATAIGMPRWRILQRILLPQIIRYSLPGLSNVWQMSLKDSALVSVTGIVELMRASQIAAGS 194
Cdd:pfam00528  66 YARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAIL 145

                         170       180       190
                  ....*....|....*....|....*....|
gi 496083293  195 TRDYFL---FYLIGGGCYLILTLLSNRAFT 221
Cdd:pfam00528 146 GYDYPEiqgPVLAAALILLLLNLLVDILQR 175
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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