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Conserved domains on  [gi|496215750|ref|WP_008929992|]
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MULTISPECIES: hypothetical protein [Gammaproteobacteria]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 709729)

helix-turn-helix (HTH) domain-containing protein with an XRE (Xenobiotic Response Element) family HTH domain, binds DNA and may function as a transcriptional regulator

CATH:  1.10.10.10
Gene Ontology:  GO:0003677
PubMed:  15808743|2644244|8831795
SCOP:  4000362

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YiaG super family cl27792
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
18-71 2.24e-03

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


The actual alignment was detected with superfamily member COG2944:

Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 32.98  E-value: 2.24e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 496215750 18 ERPTGDEIREVLRLAGLTGGGAAKKVGLGQkgdRTVRRWIGEETHIPYAAWALL 71
Cdd:COG2944   4 KPLTPEEIRALRERLGLSQAEFAALLGVSV---STVRRWEQGRRKPSGAALKLL 54
 
Name Accession Description Interval E-value
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
18-71 2.24e-03

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 32.98  E-value: 2.24e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 496215750 18 ERPTGDEIREVLRLAGLTGGGAAKKVGLGQkgdRTVRRWIGEETHIPYAAWALL 71
Cdd:COG2944   4 KPLTPEEIRALRERLGLSQAEFAALLGVSV---STVRRWEQGRRKPSGAALKLL 54
VC1465_fam NF040522
VC1465 family Xer recombination activation factor;
25-71 9.49e-03

VC1465 family Xer recombination activation factor;


Pssm-ID: 439737 [Multi-domain]  Cd Length: 111  Bit Score: 32.42  E-value: 9.49e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 496215750  25 IREVLRLAGLTGGGAAKKVGLGQkgdRTVRRWIGEETHIPYAAWALL 71
Cdd:NF040522   1 IKETREKAGLTRQQAAEMLRVSL---RTVQNWETGKVPMPYCAFKLE 44
 
Name Accession Description Interval E-value
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
18-71 2.24e-03

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 32.98  E-value: 2.24e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 496215750 18 ERPTGDEIREVLRLAGLTGGGAAKKVGLGQkgdRTVRRWIGEETHIPYAAWALL 71
Cdd:COG2944   4 KPLTPEEIRALRERLGLSQAEFAALLGVSV---STVRRWEQGRRKPSGAALKLL 54
VC1465_fam NF040522
VC1465 family Xer recombination activation factor;
25-71 9.49e-03

VC1465 family Xer recombination activation factor;


Pssm-ID: 439737 [Multi-domain]  Cd Length: 111  Bit Score: 32.42  E-value: 9.49e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 496215750  25 IREVLRLAGLTGGGAAKKVGLGQkgdRTVRRWIGEETHIPYAAWALL 71
Cdd:NF040522   1 IKETREKAGLTRQQAAEMLRVSL---RTVQNWETGKVPMPYCAFKLE 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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