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Conserved domains on  [gi|496385745|ref|WP_009094735|]
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MULTISPECIES: DNA polymerase III subunit gamma/tau [Elizabethkingia]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK14970 super family cl33047
DNA polymerase III subunits gamma and tau; Provisional
1-361 0e+00

DNA polymerase III subunits gamma and tau; Provisional


The actual alignment was detected with superfamily member PRK14970:

Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 601.86  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   1 MENFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDDTGFAFNIY 80
Cdd:PRK14970   1 MENFVVSARKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDDPNEDFSFNIF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  81 ELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
Cdd:PRK14970  81 ELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 161 IYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNILDYDYYLQ 240
Cdd:PRK14970 161 IFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNILDYDTYIN 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 241 IADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTKAKYVEQSQKWTAQELIDALE 320
Cdd:PRK14970 241 VTDLILENKIPELLLAFNEILRKGFDGHHFIAGLASHFRDLMVSKTPATIALLEVGEQAKKRYEVQSQKVSQSFLLSGID 320
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 496385745 321 ICNQADINYKNSKNQRLTVEIALMQLASLSVSDATKKKSLE 361
Cdd:PRK14970 321 IANDCDLKYKLSKNQRLLVELALMQLASINFDGISAKKKLS 361
 
Name Accession Description Interval E-value
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
1-361 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 601.86  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   1 MENFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDDTGFAFNIY 80
Cdd:PRK14970   1 MENFVVSARKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDDPNEDFSFNIF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  81 ELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
Cdd:PRK14970  81 ELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 161 IYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNILDYDYYLQ 240
Cdd:PRK14970 161 IFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNILDYDTYIN 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 241 IADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTKAKYVEQSQKWTAQELIDALE 320
Cdd:PRK14970 241 VTDLILENKIPELLLAFNEILRKGFDGHHFIAGLASHFRDLMVSKTPATIALLEVGEQAKKRYEVQSQKVSQSFLLSGID 320
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 496385745 321 ICNQADINYKNSKNQRLTVEIALMQLASLSVSDATKKKSLE 361
Cdd:PRK14970 321 IANDCDLKYKLSKNQRLLVELALMQLASINFDGISAKKKLS 361
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
5-347 7.77e-153

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 434.30  E-value: 7.77e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745    5 IVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDD------------ 72
Cdd:TIGR02397   2 QVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEpcnecesckein 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   73 TGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKII 152
Cdd:TIGR02397  82 SGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  153 PTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNI 232
Cdd:TIGR02397 162 ATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGL 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  233 LDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLM-MAQNPNtiNLIEVGEKTKAKYVEQSQKWT 311
Cdd:TIGR02397 242 VDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLlIKKTPS--NLLAVLESEQEFLKELALKLS 319
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 496385745  312 AQELIDALEICNQADINYKNSKNQRLTVEIALMQLA 347
Cdd:TIGR02397 320 LEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
13-347 2.53e-138

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 396.87  E-value: 2.53e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  13 PLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDD------------TGFAFNIY 80
Cdd:COG2812    6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEpcgecescraiaAGSHPDVI 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  81 ELDA-ASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRC 159
Cdd:COG2812   86 EIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRC 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 160 QIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRlttftqrnitlakaAETLNILDY-DYY 238
Cdd:COG2812  166 QRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQ--------------AIAFGLLDRrELL 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 239 LQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIeVGEKTKAKYVEQSQKWTAQELIDA 318
Cdd:COG2812  232 LDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELL-VNEDERERLQELARRLSPERLLRA 310
                        330       340
                 ....*....|....*....|....*....
gi 496385745 319 LEICNQADINYKNSKNQRLTVEIALMQLA 347
Cdd:COG2812  311 IQILLEARRELERNVNPRLALEMLLLRLA 339
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
21-167 6.28e-39

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 136.19  E-value: 6.28e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   21 GQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKI---NEKSGASDDTGFA-----------FNIYELDAAS 86
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALfceEPGDDLPCGQCRScrriesgnhpdLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   87 NnSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKR 166
Cdd:pfam13177  81 I-KIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159

                  .
gi 496385745  167 I 167
Cdd:pfam13177 160 L 160
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
167-231 1.42e-20

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 84.09  E-value: 1.42e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496385745 167 IQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLN 231
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
40-162 3.33e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 51.99  E-value: 3.33e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745    40 QALLFCGPRGVGKTTCARILARKINEKSG-----------ASDDTGFAFNIYELDAASNNSVDDIRELIDQVRfapqVGK 108
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGPPGGgviyidgedilEEVLDQLLLIIVGGKKASGSGELRLRLALALAR----KLK 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496385745   109 YKVYIIDEVHMLSTAAFNA--------FLKTLEEPPAHAIFILATTEKHKIIPTIL---SRCQIY 162
Cdd:smart00382  79 PDVLILDEITSLLDAEQEAllllleelRLLLLLKSEKNLTVILTTNDEKDLGPALLrrrFDRRIV 143
 
Name Accession Description Interval E-value
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
1-361 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 601.86  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   1 MENFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDDTGFAFNIY 80
Cdd:PRK14970   1 MENFVVSARKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDDPNEDFSFNIF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  81 ELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
Cdd:PRK14970  81 ELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 161 IYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNILDYDYYLQ 240
Cdd:PRK14970 161 IFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNILDYDTYIN 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 241 IADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTKAKYVEQSQKWTAQELIDALE 320
Cdd:PRK14970 241 VTDLILENKIPELLLAFNEILRKGFDGHHFIAGLASHFRDLMVSKTPATIALLEVGEQAKKRYEVQSQKVSQSFLLSGID 320
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 496385745 321 ICNQADINYKNSKNQRLTVEIALMQLASLSVSDATKKKSLE 361
Cdd:PRK14970 321 IANDCDLKYKLSKNQRLLVELALMQLASINFDGISAKKKLS 361
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
1-361 0e+00

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 596.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   1 MENFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN--------EKSGA--- 69
Cdd:PRK14971   1 MENYIVSARKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINcqnltadgEACNEces 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  70 --SDDTGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTE 147
Cdd:PRK14971  81 cvAFNEQRSYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 148 KHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAA 227
Cdd:PRK14971 161 KHKILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVI 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 228 ETLNILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTKAKYVEQS 307
Cdd:PRK14971 241 ENLNILDYDYYFRLTDALLAGKVSDSLLLFDEILNKGFDGSHFITGLASHFRDLLVCKDAATLQLLEVGESIRQRYLEQA 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 496385745 308 QKWTAQELIDALEICNQADINYKNSKNQRLTVEIALMQLASLSVSDATKKKSLE 361
Cdd:PRK14971 321 QKCPMSFLYRALKLCNQCDLNYRASKNKRLLVELTLIQLAQLTQKGDDASGGRG 374
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
5-347 7.77e-153

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 434.30  E-value: 7.77e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745    5 IVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDD------------ 72
Cdd:TIGR02397   2 QVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEpcnecesckein 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   73 TGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKII 152
Cdd:TIGR02397  82 SGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  153 PTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNI 232
Cdd:TIGR02397 162 ATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGL 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  233 LDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLM-MAQNPNtiNLIEVGEKTKAKYVEQSQKWT 311
Cdd:TIGR02397 242 VDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLlIKKTPS--NLLAVLESEQEFLKELALKLS 319
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 496385745  312 AQELIDALEICNQADINYKNSKNQRLTVEIALMQLA 347
Cdd:TIGR02397 320 LEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
9-362 5.82e-145

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 421.59  E-value: 5.82e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   9 RKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEK------------------SGAS 70
Cdd:PRK05563   8 RKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLnppdgepcneceickaitNGSL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  71 DDtgfafnIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHK 150
Cdd:PRK05563  88 MD------VIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPHK 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 151 IIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETL 230
Cdd:PRK05563 162 IPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEVT 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 231 NILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTKAKYVEQSQKW 310
Cdd:PRK05563 242 GSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEILDESTENDELFKELSEKL 321
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
gi 496385745 311 TAQELIDALEICNQADINYKNSKNQRLTVEIALMQLASLSVSDATKKKSLES 362
Cdd:PRK05563 322 DIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQAAASPEYDTELEV 373
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
13-347 2.53e-138

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 396.87  E-value: 2.53e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  13 PLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDD------------TGFAFNIY 80
Cdd:COG2812    6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEpcgecescraiaAGSHPDVI 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  81 ELDA-ASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRC 159
Cdd:COG2812   86 EIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRC 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 160 QIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRlttftqrnitlakaAETLNILDY-DYY 238
Cdd:COG2812  166 QRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQ--------------AIAFGLLDRrELL 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 239 LQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIeVGEKTKAKYVEQSQKWTAQELIDA 318
Cdd:COG2812  232 LDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELL-VNEDERERLQELARRLSPERLLRA 310
                        330       340
                 ....*....|....*....|....*....
gi 496385745 319 LEICNQADINYKNSKNQRLTVEIALMQLA 347
Cdd:COG2812  311 IQILLEARRELERNVNPRLALEMLLLRLA 339
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
9-345 4.94e-112

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 338.32  E-value: 4.94e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   9 RKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN----EKSG---------ASDDTGF 75
Cdd:PRK14950   8 RKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNcttnDPKGrpcgtcemcRAIAEGS 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  76 AFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTI 155
Cdd:PRK14950  88 AVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPATI 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 156 LSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNILDY 235
Cdd:PRK14950 168 LSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQSLLGISGD 247
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 236 DYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTKAKYVEQSQKWTAQEL 315
Cdd:PRK14950 248 EEVKALAEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLRQVMLLNSGADRSLLDLTADEKAALQKVSQIANLEAL 327
                        330       340       350
                 ....*....|....*....|....*....|
gi 496385745 316 IDALEICNQADINYKNSKNQRLTVEIALMQ 345
Cdd:PRK14950 328 TKWVKAFSQLDFQLRTTSYGQLPLELAVIE 357
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
3-350 1.18e-108

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 329.39  E-value: 1.18e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   3 NFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDD---------- 72
Cdd:PRK14965   2 SYLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEpcnvcppcve 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  73 --TGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHK 150
Cdd:PRK14965  82 itEGRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHK 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 151 IIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETL 230
Cdd:PRK14965 162 VPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAELL 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 231 NILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQN-PNTINLIEVGEKTKAKYVEQSQK 309
Cdd:PRK14965 242 GVVDRRLLLDISAAVFGRDTRALLEIVERVDEFGYNMRQFCQELIDHLRNLVVLRAvGEPGDLLDLSEAELAELRAQAAA 321
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 496385745 310 WTAQELIDALEICNQADINYKNSKNQRLTVEIALMQLASLS 350
Cdd:PRK14965 322 ADAADLQRHLTLLLRAEGEMAHASFPRLVLEMALLKMATLA 362
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
10-346 3.58e-107

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 326.92  E-value: 3.58e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  10 KYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINekSGASDD----------------T 73
Cdd:PRK14948   9 KYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLN--CLNSDKptpepcgkcelcraiaA 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK14948  87 GNALDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTDPQRVLP 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQrNITLAKAAETLNIL 233
Cdd:PRK14948 167 TIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQLSLLPG-PITPEAVWDLLGAV 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 234 DYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDL-MMAQNPNTINLIEVGEKTKAKYVEQSQKWTA 312
Cdd:PRK14948 246 PEQDLLNLLKALASNDPESLLDSCRQLLDRGREPLAILQGLAAFYRDLlLAKTAPNRPDLVAVSQQTWDELCKLAKQINL 325
                        330       340       350
                 ....*....|....*....|....*....|....
gi 496385745 313 QELIDALEICNQADINYKNSKNQRLTVEIALMQL 346
Cdd:PRK14948 326 ERILQWQQHLKGSEYQLKNSTQPRLWLEVTLLGL 359
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
6-349 1.05e-106

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 325.74  E-value: 1.05e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN---------------EKSGAS 70
Cdd:PRK14954   5 VIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNcqrmiddpvylqevtEPCGEC 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  71 D-----DTGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILAT 145
Cdd:PRK14954  85 EscrdfDAGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFAT 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 146 TEKHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFT-----QRN 220
Cdd:PRK14954 165 TELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFSvgseaEKV 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 221 ITLAKAAETLNILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTK 300
Cdd:PRK14954 245 IAYQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDEQDFLEKLIEHFRNFLVLYNLRSTRLIERPESVK 324
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 496385745 301 AKYVEQSQKWTAQELIDALEICNQADINYKNSKNQRLTVEIALMQLASL 349
Cdd:PRK14954 325 ERYQQSAGGLTPAAVMQMTDFLMKTQGELKFQFEYQFRFELALLRLIEL 373
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
6-362 8.37e-106

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 316.06  E-value: 8.37e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN---------------EKSGAS 70
Cdd:PRK14955   5 VIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNcqrmiddadylqevtEPCGEC 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  71 D-----DTGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILAT 145
Cdd:PRK14955  85 EscrdfDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFAT 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 146 TEKHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFT-----QRN 220
Cdd:PRK14955 165 TELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAFSvesegEGS 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 221 ITLAKAAETLNILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTK 300
Cdd:PRK14955 245 IRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVVHNLRSTRLVERPDAVR 324
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 496385745 301 AKYVEQSQKWTAQELIDALEICNQADINYKNSKNQRLTVEIALMQLASLSVSDAT----------KKKSLES 362
Cdd:PRK14955 325 ERYERDAAKFSPEVIMQMTDLLLQTQKELKFQFEYQFRFELALLKLIEIGHPAPTaaaaptggaqKKKPLLS 396
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
3-361 5.96e-94

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 295.57  E-value: 5.96e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   3 NFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN-----------EKSGASD 71
Cdd:PRK07133   4 KYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNcshktdllepcQECIENV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  72 DTgfAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKI 151
Cdd:PRK07133  84 NN--SLDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKI 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 152 IPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLN 231
Cdd:PRK07133 162 PLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVEELFG 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 232 ILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTKAKYVEQSQKwT 311
Cdd:PRK07133 242 LVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKEFIIFNKTKDNSLLEYYSEEDLEKLKIDDD-F 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 496385745 312 AQELIDALeICNQADINYknSKNQRLTVEIALMQLASLSVSDATKKKSLE 361
Cdd:PRK07133 321 AYKFIEIL-FDLLKDLKI--SDNPNDTLEILIIKLLALSELEEEDENEIK 367
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
6-211 2.18e-92

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 287.95  E-value: 2.18e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKsGASDDTGFAF-------- 77
Cdd:PRK09111  13 VLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYE-GPDGDGGPTIdlcgvgeh 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  78 ----------NIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTE 147
Cdd:PRK09111  92 cqaimegrhvDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATTE 171
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 496385745 148 KHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFD 211
Cdd:PRK09111 172 IRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLD 235
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
6-362 7.46e-91

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 283.20  E-value: 7.46e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGA------------SDDT 73
Cdd:PRK06647   5 GTATKRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPtpmpcgecssckSIDN 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK06647  85 DNSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPA 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNIL 233
Cdd:PRK06647 165 TIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSKMGLT 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 234 DYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTiNLIEVGEKTKaKYVEQSQKWTAQ 313
Cdd:PRK06647 245 GDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLDCIEFFRELLFLKHGIK-NEAFIGIKAE-RLPEKLREFDLS 322
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 496385745 314 ELIDALEICNQA--DINYknSKNQRLTVEIALMQLASLS--VSDATKKKSLES 362
Cdd:PRK06647 323 QIERAISVLLETyrDLQF--SVNPRYELEINFSKILRLKdyVPNHELIKQIQD 373
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
3-284 1.07e-89

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 277.86  E-value: 1.07e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   3 NFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN-------EKSGASD---- 71
Cdd:PRK14953   2 MYIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNclnpqegEPCGKCEncve 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  72 -DTGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHK 150
Cdd:PRK14953  82 iDKGSFPDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDK 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 151 IIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETL 230
Cdd:PRK14953 162 IPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEFL 241
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 496385745 231 NILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMA 284
Cdd:PRK14953 242 GIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEIRNILLN 295
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
1-319 4.21e-88

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 272.42  E-value: 4.21e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   1 MENFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASD--------- 71
Cdd:PRK06305   1 MTSYQVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNPTEDqepcnqcas 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  72 ----DTGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTE 147
Cdd:PRK06305  81 ckeiSSGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 148 KHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAA 227
Cdd:PRK06305 161 IHKIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 228 ETLNILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNpntinlievgektKAKYVEQS 307
Cdd:PRK06305 241 KALGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDLTLFFRNILLKQY-------------NKQLSSVA 307
                        330
                 ....*....|....*
gi 496385745 308 QKWTAQ---ELIDAL 319
Cdd:PRK06305 308 TKYSSEqllEIIDFL 322
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
3-305 8.86e-88

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 276.34  E-value: 8.86e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   3 NFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN---EKSG---------AS 70
Cdd:PRK05896   2 SEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINclnPKDGdccnscsvcES 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  71 DDTGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHK 150
Cdd:PRK05896  82 INTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQK 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 151 IIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETL 230
Cdd:PRK05896 162 IPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKTF 241
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496385745 231 NILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLIEVGEKTKAKYVE 305
Cdd:PRK05896 242 GLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLIDLLVYQKTKNINLLKKLSKEQLKTLN 316
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
9-285 1.15e-86

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 270.56  E-value: 1.15e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   9 RKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN-----------------EKSGASD 71
Cdd:PRK14963   6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNcsgedpkpcgecesclaVRRGAHP 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  72 DtgfafnIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKI 151
Cdd:PRK14963  86 D------VLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKM 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 152 IPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTfTQRNITLAKAAETLN 231
Cdd:PRK14963 160 PPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLA-LGTPVTRKQVEEALG 238
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 496385745 232 ILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQ 285
Cdd:PRK14963 239 LPPQERLRGIAAALAQGDAAEALSGAAQLYRDGFAARTLVEGLLEAFRAALYAE 292
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
6-254 1.65e-83

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 263.15  E-value: 1.65e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASD------------DT 73
Cdd:PRK14969   5 VLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTAtpcgvcsacleiDS 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK14969  85 GRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNIL 233
Cdd:PRK14969 165 TVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAMLGAI 244
                        250       260
                 ....*....|....*....|.
gi 496385745 234 DYDYYLQIADFAKSNDIPGIL 254
Cdd:PRK14969 245 DQDYLFALLEALLAQDGAALL 265
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
6-241 3.20e-81

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 260.18  E-value: 3.20e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASD------------DT 73
Cdd:PRK07994   5 VLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITAtpcgecdncreiEQ 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK07994  85 GRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNIL 233
Cdd:PRK07994 165 TILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAMLGTL 244

                 ....*...
gi 496385745 234 DYDYYLQI 241
Cdd:PRK07994 245 DDDQALSL 252
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
9-271 1.08e-79

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 251.61  E-value: 1.08e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   9 RKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN-EK-----------SGASDDTGFA 76
Cdd:PRK14962   6 RKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNcENrkgvepcnecrACRSIDEGTF 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  77 FNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTIL 156
Cdd:PRK14962  86 MDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTII 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 157 SRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNILDYD 236
Cdd:PRK14962 166 SRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGLIPIE 245
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 496385745 237 YYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFI 271
Cdd:PRK14962 246 VVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLI 280
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
6-234 3.72e-78

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 249.18  E-value: 3.72e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASD---DT--------- 73
Cdd:PRK08451   3 ALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSStpcDTciqcqsale 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK08451  83 NRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNIL 233
Cdd:PRK08451 163 TILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGLL 242

                 .
gi 496385745 234 D 234
Cdd:PRK08451 243 D 243
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
4-264 1.21e-77

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 252.10  E-value: 1.21e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   4 FIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINeKSGASDDTGFA------- 76
Cdd:PRK12323   3 YQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLN-CTGADGEGGITaqpcgqc 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  77 ----------FNIY-ELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILAT 145
Cdd:PRK12323  82 racteidagrFVDYiEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILAT 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 146 TEKHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAK 225
Cdd:PRK12323 162 TDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEEA 241
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 496385745 226 AAETLNILDYDYYLQIADFAKSNDIPGILSKLNEIVNKG 264
Cdd:PRK12323 242 VRGMLGAIDQSYLVRLLDALAAEDGAALLAIADEMAGRS 280
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
2-271 1.21e-77

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 246.78  E-value: 1.21e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   2 ENFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN-----------EKSGAS 70
Cdd:PRK14956   3 GTHEVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNcenpignepcnECTSCL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  71 DDT-GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKH 149
Cdd:PRK14956  83 EITkGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFH 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 150 KIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAET 229
Cdd:PRK14956 163 KIPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKM 242
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 496385745 230 LNILDYDYYlqiADFAKSNDIPGILSKLNEIV----NKGFDPHIFI 271
Cdd:PRK14956 243 IGYHGIEFL---TSFIKSLIDPDNHSKSLEILeslyQEGQDIYKFL 285
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
4-243 1.26e-74

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 242.31  E-value: 1.26e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   4 FIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN--EKSGASD---------- 71
Cdd:PRK14951   3 YLVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNcqGPDGQGGitatpcgvcq 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  72 -----DTGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATT 146
Cdd:PRK14951  83 acrdiDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATT 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 147 EKHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKA 226
Cdd:PRK14951 163 DPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEAAV 242
                        250
                 ....*....|....*..
gi 496385745 227 AETLNILDYDYYLQIAD 243
Cdd:PRK14951 243 RQMLGSVDRSHVFRLID 259
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
6-266 6.30e-74

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 242.69  E-value: 6.30e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASD------------DT 73
Cdd:PRK08691   5 VLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGepcgvcqsctqiDA 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK08691  85 GRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNIL 233
Cdd:PRK08691 165 TVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQMIGAV 244
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 496385745 234 DYDYYLQIADFAKSNDIPGILSKLNEIVNK--GFD 266
Cdd:PRK08691 245 DKQYLYELLTGIINQDGAALLAKAQEMAACavGFD 279
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
9-354 1.73e-73

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 238.63  E-value: 1.73e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   9 RKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSG---------------ASDDT 73
Cdd:PRK14952   5 RKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGptatpcgvcescvalAPNGP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GfAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK14952  85 G-SIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLP 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRL--------TTFtQRNITLAK 225
Cdd:PRK14952 164 TIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLlagaadthVTY-QRALGLLG 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 226 AAETlnILDYDYYLQIAdfakSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQ---NPNTINLIEVGEKTKAK 302
Cdd:PRK14952 243 ATDV--ALIDDAVDALA----ADDAAALFGAIESVIDAGHDPRRFATDLLERFRDLIVLQavpDAAARGVVDAPEDVLER 316
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
gi 496385745 303 YVEQSQKWTAQELIDALEICNQADINYKNSKNQRLTVEIALMQLASLSVSDA 354
Cdd:PRK14952 317 MREQAARIGLATLTRYAEVVQAGLGEMRGATAPRLLLEVVCARLLLPSASDA 368
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
8-262 1.21e-72

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 233.91  E-value: 1.21e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   8 ARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSG-ASDDTGFAFN-------- 78
Cdd:PRK14964   4 ALKYRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGpTSDPCGTCHNcisiknsn 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  79 ---IYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTI 155
Cdd:PRK14964  84 hpdVIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVTI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 156 LSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNILDY 235
Cdd:PRK14964 164 ISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCVDK 243
                        250       260
                 ....*....|....*....|....*..
gi 496385745 236 DYYLQIADFAKSNDIPGILSKLNEIVN 262
Cdd:PRK14964 244 HILEDLVEAILLGDAQSALNVFRELCN 270
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
9-285 2.62e-72

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 240.27  E-value: 2.62e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   9 RKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDD------------TGFA 76
Cdd:PRK07764   7 RRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTpcgecdscvalaPGGP 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  77 FNI--YELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPT 154
Cdd:PRK07764  87 GSLdvTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKVIGT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 155 ILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLttftqrnitLAKAAEtlNILD 234
Cdd:PRK07764 167 IRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQL---------LAGAGP--EGVT 235
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 496385745 235 YDY---YLQIADFA---------KSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQ 285
Cdd:PRK07764 236 YERavaLLGVTDSAlideavdalAAGDGAALFGTVDRVIEAGHDPRRFAEDLLERLRDLIVLQ 298
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
6-260 3.68e-70

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 234.74  E-value: 3.68e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASD------------DT 73
Cdd:PRK07003   5 VLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSqpcgvcracreiDE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK07003  85 GRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNIL 233
Cdd:PRK07003 165 TVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGMLGAL 244
                        250       260
                 ....*....|....*....|....*..
gi 496385745 234 DYDYYLQIADFAKSNDIPGILSKLNEI 260
Cdd:PRK07003 245 DQTYMVRLLDALAAGDGPEILAVADEM 271
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
6-315 4.58e-70

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 232.25  E-value: 4.58e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASD------------DT 73
Cdd:PRK14960   4 VLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTStpcevcatckavNE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK14960  84 GRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNIL 233
Cdd:PRK14960 164 TVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLGLI 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 234 D----YDYYLQIadfaKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINLiEVGEKTKAKYVEQSQK 309
Cdd:PRK14960 244 DrtiiYDLILAV----HQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPELGL-KYSEEINAKILQLSKL 318

                 ....*.
gi 496385745 310 WTAQEL 315
Cdd:PRK14960 319 ISAQDL 324
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
1-349 1.56e-69

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 229.18  E-value: 1.56e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   1 MENFIVSARkYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDD-------- 72
Cdd:PRK14959   1 MSHASLTAR-YRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEpcntceqc 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  73 ----TGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEK 148
Cdd:PRK14959  80 rkvtQGMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEP 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 149 HKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAE 228
Cdd:PRK14959 160 HKFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARG 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 229 TLNILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMAQNPNTINL--IEVGEKTKAKYVEQ 306
Cdd:PRK14959 240 VLGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVATWRNLFMLRQAGEAALasLDLPEDEARQWLGW 319
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|...
gi 496385745 307 SQKWTAQELIDALEICNQADINYKNSKNQRLTVEIALMQLASL 349
Cdd:PRK14959 320 AKRFEPAHIHACWQMTLEGQRRVLTSLEPAMALELLLLNLAML 362
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
3-260 3.58e-69

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 221.22  E-value: 3.58e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   3 NFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDD---------- 72
Cdd:PRK14961   2 NYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNpcrkciicke 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  73 --TGFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHK 150
Cdd:PRK14961  82 ieKGLCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEK 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 151 IIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETL 230
Cdd:PRK14961 162 IPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDML 241
                        250       260       270
                 ....*....|....*....|....*....|
gi 496385745 231 NILDYDYYLQIADFAKSNDIPGILSKLNEI 260
Cdd:PRK14961 242 GLLNEKQSFLLTDALLKKDSKKTMLLLNKI 271
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
3-271 4.56e-66

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 217.03  E-value: 4.56e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   3 NFIVSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDDTGF------- 75
Cdd:PRK06645   7 QYIPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALITENTTIktceqct 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  76 ---AFN------IYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATT 146
Cdd:PRK06645  87 nciSFNnhnhpdIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 147 EKHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRN---ITL 223
Cdd:PRK06645 167 EVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSAKSdniISP 246
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 496385745 224 AKAAETLNILDYDYYLQIADFAKSNDIPGILSKLNEIVNKGFDPHIFI 271
Cdd:PRK06645 247 QVINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFI 294
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
8-254 5.22e-62

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 207.63  E-value: 5.22e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   8 ARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSG-------------ASDDTG 74
Cdd:PRK14957   7 ARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGvtaepcnkcencvAINNNS 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  75 FaFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPT 154
Cdd:PRK14957  87 F-IDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVT 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 155 ILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNILD 234
Cdd:PRK14957 166 ILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQMLGIID 245
                        250       260
                 ....*....|....*....|
gi 496385745 235 YDYYLQIADFAKSNDIPGIL 254
Cdd:PRK14957 246 SEEVYSIINAIIDNDPKAIL 265
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
6-216 1.09e-61

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 212.66  E-value: 1.09e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSG--ASD----------DT 73
Cdd:PRK14949   5 VLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGvtATPcgvcsscveiAQ 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK14949  85 GRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPV 164
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTF 216
Cdd:PRK14949 165 TVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAF 227
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
6-266 2.39e-58

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 196.87  E-value: 2.39e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   6 VSARKYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASD------------DT 73
Cdd:PRK14958   5 VLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSAnpcndcencreiDE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
Cdd:PRK14958  85 GRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 154 TILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLNIL 233
Cdd:PRK14958 165 TVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTMLGTI 244
                        250       260       270
                 ....*....|....*....|....*....|...
gi 496385745 234 DYDYYLQIADFAKSNDIPGILSKLNEIVNKGFD 266
Cdd:PRK14958 245 EPLLLFDILEALAAKAGDRLLGCVTRLVEQGVD 277
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
22-263 3.04e-48

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 164.38  E-value: 3.04e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  22 QSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKI-----------NEKSGASDDTGFAFNIYELDAASNN-- 88
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLlcenpeggkacGQCHSRLMAAGNHPDLLELNPEEKSdq 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  89 -SVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKRI 167
Cdd:COG0470   81 iGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRPP 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 168 QIEDIQNHLRkiadKEGIqyEDDALFLVAQKADGALRDAL----------SIFDRLTTFTQRN--ITLAKAAETLNILDY 235
Cdd:COG0470  161 SEEEALAWLR----EEGV--DEDALEAILRLAGGDPRAAInllqalagrkELLEDLAALLSRDraLELLDALLKAEALEL 234
                        250       260       270
                 ....*....|....*....|....*....|
gi 496385745 236 DYYLQ--IADFAKSNDIPGILSKLNEIVNK 263
Cdd:COG0470  235 LDWLLkwLLDNLPLEYAGEDLARAYEALSE 264
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
21-167 6.28e-39

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 136.19  E-value: 6.28e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   21 GQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKI---NEKSGASDDTGFA-----------FNIYELDAAS 86
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALfceEPGDDLPCGQCRScrriesgnhpdLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   87 NnSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKR 166
Cdd:pfam13177  81 I-KIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159

                  .
gi 496385745  167 I 167
Cdd:pfam13177 160 L 160
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
8-247 2.89e-38

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 141.38  E-value: 2.89e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   8 ARKYRPLEFDTVVGQSHITDT---LEHAIDNNQLAQALLFcGPRGVGKTTCARILARKineksgasddTGFAFniYELDA 84
Cdd:PRK13342   3 AERMRPKTLDEVVGQEHLLGPgkpLRRMIEAGRLSSMILW-GPPGTGKTTLARIIAGA----------TDAPF--EALSA 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  85 AsNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEppAHAIFILATTE--KHKIIPTILSRCQIY 162
Cdd:PRK13342  70 V-TSGVKDLREVIEEARQRRSAGRRTILFIDEIHRFNKAQQDALLPHVED--GTITLIGATTEnpSFEVNPALLSRAQVF 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 163 DFKRIQIEDIQNHLRK-IADKEG--IQYEDDALFLVAQKADGALRDALSIFDrLTTFTQRNITLAKAAETL--NILDYD- 236
Cdd:PRK13342 147 ELKPLSEEDIEQLLKRaLEDKERglVELDDEALDALARLANGDARRALNLLE-LAALGVDSITLELLEEALqkRAARYDk 225
                        250
                 ....*....|....*
gi 496385745 237 ----YYLQIADFAKS 247
Cdd:PRK13342 226 dgdeHYDLISALHKS 240
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
29-206 2.31e-36

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 130.44  E-value: 2.31e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   29 LEHAIDNNQLAQALLFCGPRGVGKTTCARILARKIN-EKSGASDDTGFAFNIYELDAAS----------NNS--VDDIRE 95
Cdd:TIGR00678   4 LKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLcEQRGGGEPCGECHSCRLIEAGNhpdlhrlepeGQSikVDQVRE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   96 LIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKRIQIEDIQNH 175
Cdd:TIGR00678  84 LVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALLQW 163
                         170       180       190
                  ....*....|....*....|....*....|.
gi 496385745  176 LRkiadKEGIQYEDDAlfLVAQKADGALRDA 206
Cdd:TIGR00678 164 LI----RQGISEEAAE--LLLALAGGSPGRA 188
rfc PRK00440
replication factor C small subunit; Reviewed
10-209 3.50e-31

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 119.98  E-value: 3.50e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  10 KYRPLEFDTVVGQSHITDTLEHAIDNNQLAQaLLFCGPRGVGKTTCARILARKIneksgASDDtgFAFNIYELDAASNNS 89
Cdd:PRK00440  10 KYRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALAREL-----YGED--WRENFLELNASDERG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  90 VDDIRELI-DQVRFAPqVGK--YKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKR 166
Cdd:PRK00440  82 IDVIRNKIkEFARTAP-VGGapFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFRFSP 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 496385745 167 IQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSI 209
Cdd:PRK00440 161 LKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINA 203
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
10-266 3.67e-31

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 120.48  E-value: 3.67e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  10 KYRPLEFDTVVGQSHITDTLEHAIDNNQLAQaLLFCGPRGVGKTTCARILARKINEKSGASDDTGFA----FN------- 78
Cdd:PRK12402   8 KYRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALARELYGDPWENNFTEFNvadfFDqgkkylv 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  79 -------IYELDAASNNSV-DDIRELI-DQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKH 149
Cdd:PRK12402  87 edprfahFLGTDKRIRSSKiDNFKHVLkEYASYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIATRQPS 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 150 KIIPTILSRC-QIYdFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALsIFDRLTTFTQRNITLAKAAE 228
Cdd:PRK12402 167 KLIPPIRSRClPLF-FRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAI-LTLQTAALAAGEITMEAAYE 244
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 496385745 229 TLNILDYD-YYLQIADFAKSNDIPGILSKLNE-IVNKGFD 266
Cdd:PRK12402 245 ALGDVGTDeVIESLLDAAEAGDFTDARKTLDDlLIDEGLS 284
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
12-247 6.90e-31

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 121.70  E-value: 6.90e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  12 RPLEFDTVVGQSHITD---TLEHAIDNNQLAqALLFCGPRGVGKTTCARILARKineksgasddTGFAFniYELDAASNN 88
Cdd:COG2256   20 RPRTLDEVVGQEHLLGpgkPLRRAIEAGRLS-SMILWGPPGTGKTTLARLIANA----------TDAEF--VALSAVTSG 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  89 sVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEppAHAIFILATTEK--HKIIPTILSRCQIYDFKR 166
Cdd:COG2256   87 -VKDIREVIEEARERRAYGRRTILFVDEIHRFNKAQQDALLPHVED--GTITLIGATTENpsFEVNSALLSRCRVFVLKP 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 167 IQIEDIQNHLRK-IADKE------GIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRN----ITLAKAAETL--NIL 233
Cdd:COG2256  164 LSEEDLEQLLERaLADDErglggyKLELDDEALEALARLADGDARRALNALELAVLSAPPDgvieITLELVEEALqrRAL 243
                        250
                 ....*....|....*....
gi 496385745 234 DYD-----YYLQIADFAKS 247
Cdd:COG2256  244 RYDkdgdeHYDLISAFIKS 262
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
16-260 2.65e-27

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 109.60  E-value: 2.65e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  16 FDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDDT---------------------- 73
Cdd:PRK07399   3 FANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGLLSQGSPSKNIrrrleegnhpdllwveptyqhq 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  74 GFAFNIYELDAA--SNNSVDDIRelIDQVR----F---APQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPpAHAIFILA 144
Cdd:PRK07399  83 GKLITASEAEEAglKRKAPPQIR--LEQIReikrFlsrPPLEAPRKVVVIEDAETMNEAAANALLKTLEEP-GNGTLILI 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 145 TTEKHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDAL--------SIFDRLTTF 216
Cdd:PRK07399 160 APSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPELLALAQGSPGAAIANIeqlqsippELLQKLEQP 239
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 496385745 217 TQRNI---TLAKA-AETLNI------LDydyYLQIADFAKSNDIPgILSKLNEI 260
Cdd:PRK07399 240 PKSPLealELAKDiSEELDIeqqlwlID---YLQQHYWQKTKNRQ-LLKQLEKL 289
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
14-178 3.69e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 103.57  E-value: 3.69e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  14 LEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGasdDTGFAfNIYELDAASNNS--VD 91
Cdd:PRK05564   1 MSFHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIALKILGKSQ---QREYV-DIIEFKPINKKSigVD 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  92 DIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKRIQIED 171
Cdd:PRK05564  77 DIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEE 156

                 ....*..
gi 496385745 172 IQNHLRK 178
Cdd:PRK05564 157 IEKFISY 163
PLN03025 PLN03025
replication factor C subunit; Provisional
10-207 2.38e-24

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 101.34  E-value: 2.38e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  10 KYRPLEFDTVVGQSHITDTLEhAIDNNQLAQALLFCGPRGVGKTTCARILARkinEKSGASddtgFAFNIYELDAASNNS 89
Cdd:PLN03025   6 KYRPTKLDDIVGNEDAVSRLQ-VIARDGNMPNLILSGPPGTGKTTSILALAH---ELLGPN----YKEAVLELNASDDRG 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  90 VDDIRELID---QVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKR 166
Cdd:PLN03025  78 IDVVRNKIKmfaQKKVTLPPGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFSR 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 496385745 167 IQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDAL 207
Cdd:PLN03025 158 LSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQAL 198
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
167-231 1.42e-20

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 84.09  E-value: 1.42e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496385745 167 IQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFTQRNITLAKAAETLN 231
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
13-321 1.75e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 85.47  E-value: 1.75e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  13 PLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKI------NEKSGASDDTGFAFNIYELDA-- 84
Cdd:PRK09112  19 PSENTRLFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLAFHLANHIlshpdpAEAPETLADPDPASPVWRQIAqg 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  85 ASNN-------------------SVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILAT 145
Cdd:PRK09112  99 AHPNllhitrpfdektgkfktaiTVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILIS 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 146 TEKHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLvaQKADGALRDALsifdRLTTFTQRNItlAK 225
Cdd:PRK09112 179 HSSGRLLPTIRSRCQPISLKPLDDDELKKALSHLGSSQGSDGEITEALL--QRSKGSVRKAL----LLLNYGGLEI--IA 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 226 AAETLnildydyylqiadFAKSNDIPGILSKLNEIVNkGFDPHIFIGGLGSHFRDLMMAqnpNTINLIEVGEKTKAKyvE 305
Cdd:PRK09112 251 TIDQL-------------LAGSGPDARKAHKLADALS-GRESEVQFDFFRDHLLDRIMA---EARRAAEAGDLALAE--R 311
                        330
                 ....*....|....*.
gi 496385745 306 QSQKWtaQELIDALEI 321
Cdd:PRK09112 312 LARLW--SEIIEEIVE 325
PRK04195 PRK04195
replication factor C large subunit; Provisional
10-266 3.20e-18

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 85.74  E-value: 3.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  10 KYRPLEFDTVVGQSHITDTLEHAID---NNQLAQALLFCGPRGVGKTTCARILARKINeksgasddtgfaFNIYELDAAS 86
Cdd:PRK04195   7 KYRPKTLSDVVGNEKAKEQLREWIEswlKGKPKKALLLYGPPGVGKTSLAHALANDYG------------WEVIELNASD 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  87 NNSVDDIRELIDQvrfAPQVG-----KYKVYIIDEVHMLS----TAAFNAFLKTLEEPpahaifilatteKHKII----- 152
Cdd:PRK04195  75 QRTADVIERVAGE---AATSGslfgaRRKLILLDEVDGIHgnedRGGARAILELIKKA------------KQPIIltand 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 153 ------PTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDA-------------------- 206
Cdd:PRK04195 140 pydpslRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAindlqaiaegygkltledvk 219
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 207 --------LSIFDRLT-TFTQRNITLAKAAETLNILDYDYYLQ-IADfaksnDIPGILSKLNEIVnKGFD 266
Cdd:PRK04195 220 tlgrrdreESIFDALDaVFKARNADQALEASYDVDEDPDDLIEwIDE-----NIPKEYDDPEDIA-RAYD 283
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
37-160 9.35e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 82.83  E-value: 9.35e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  37 QLAQALLFCGPRGVGKTTCA-RILARKINEKSGASDDTGFA--------------FNIYELDAASNNSVDDIRELIDQVR 101
Cdd:PRK05707  20 RHPHAYLLHGPAGIGKRALAeRLAAALLCEAPQGGGACGSCkgcqllragshpdnFVLEPEEADKTIKVDQVRELVSFVV 99
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 496385745 102 FAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
Cdd:PRK05707 100 QTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQ 158
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
22-185 9.98e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 83.05  E-value: 9.98e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  22 QSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKI--NEKSGASDDtGFAFNIYELDaaSNNSvDDIREL--- 96
Cdd:PRK08058  11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLfcLERNGVEPC-GTCTNCKRID--SGNH-PDVHLVapd 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  97 -----IDQVRFAPQV-------GKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDF 164
Cdd:PRK08058  87 gqsikKDQIRYLKEEfsksgveSNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEF 166
                        170       180
                 ....*....|....*....|.
gi 496385745 165 KRIQIEDIQNHLrkiaDKEGI 185
Cdd:PRK08058 167 RPLPPESLIQRL----QEEGI 183
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
16-161 6.98e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 81.11  E-value: 6.98e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  16 FDTVVGQSHITDTLEHA---------IDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDDTGFAFNIYELDAAS 86
Cdd:PRK07940   4 WDDLVGQEAVVAELRAAaraaradvaAAGSGMTHAWLFTGPPGSGRSVAARAFAAALQCTDPDEPGCGECRACRTVLAGT 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  87 NN------------SVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPT 154
Cdd:PRK07940  84 HPdvrvvapeglsiGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPT 163

                 ....*..
gi 496385745 155 ILSRCQI 161
Cdd:PRK07940 164 IRSRCRH 170
44 PHA02544
clamp loader, small subunit; Provisional
10-192 9.02e-17

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 80.03  E-value: 9.02e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  10 KYRPLEFDTVVGQSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKsgasddtgfafniYELDAASNNS 89
Cdd:PHA02544  14 KYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTVAKALCNEVGAE-------------VLFVNGSDCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  90 VDDIRELIDqvRFAPQV---GKYKVYIIDEVHMLSTAAFNAFLKTL-EEPPAHAIFILATTEKHKIIPTILSRCQIYDFk 165
Cdd:PHA02544  81 IDFVRNRLT--RFASTVsltGGGKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITANNKNGIIEPLRSRCRVIDF- 157
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 496385745 166 RIQIEDIQNHLRK--------IADKEGIQYEDDAL 192
Cdd:PHA02544 158 GVPTKEEQIEMMKqmivrckgILEAEGVEVDMKVL 192
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
77-330 3.55e-16

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 77.99  E-value: 3.55e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  77 FNIYELDAASnnsvDDIRELIDQVRFAPQVGKYKVYIIDEVHMLS--TAAFNAFLKTLEEPPAHAIFILAT---TEKHKI 151
Cdd:COG1466   35 FNRTRLDGAE----TDWAELLDEAQTLSLFGERRLVIVRNAEFLKkpGEGLEALEAYLANPPPDTVLVLTAgklDKRKKL 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 152 IPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRLTTFT--QRNITLAKAAET 229
Cdd:COG1466  111 FKALEKAGVVVECYPLKERELPAWIRQRLKAAGLRIDPDAAQLLAERVGGDLLALAQELEKLALYAgdGGTITLEDVEAL 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 230 LNI-LDYDYYlQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLMMA-------QNPNTI-NLIEVGEKTK 300
Cdd:COG1466  191 VGDsAEFNVF-DLADALLAGDAARALRILRRLLAEGEEPVLILAALARQFRLLLQVkallaqgKSLAEIaKELGVPPFRV 269
                        250       260       270
                 ....*....|....*....|....*....|
gi 496385745 301 AKYVEQSQKWTAQELIDALEICNQADINYK 330
Cdd:COG1466  270 KLALRALRRWSLERLARALQLLAEADLALK 299
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
31-224 4.79e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 77.99  E-value: 4.79e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  31 HAIDNNQLAQ-------ALLFCGPRGVGKTTCARILARKINEKSGASD-------------DTGFAFNIYELDAASNN-- 88
Cdd:PRK08699   6 HQEQWRQIAEhwerrpnAWLFAGKKGIGKTAFARFAAQALLCETPAPGhkpcgecmschlfGQGSHPDFYEITPLSDEpe 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  89 --------SVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
Cdd:PRK08699  86 ngrkllqiKIDAVREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCR 165
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 496385745 161 IYDFKRIQIEDIQNHLRK--IADKEG----------IQYEDDALFLVAQKADG-ALRDALSIFDRLTTFTQRNITLA 224
Cdd:PRK08699 166 KMVLPAPSHEEALAYLRErgVAEPEErlafhsgaplFDEEPELRALRIKLLDIlAEPRLLKILDYAALFDKEKLPLA 242
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
38-214 7.28e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 77.76  E-value: 7.28e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  38 LAQALLFCGPRGVGKTTCARILARKI-------NEKSGASDDT---------------GFAFNIYELDAASNN------- 88
Cdd:PRK07471  40 LHHAWLIGGPQGIGKATLAYRMARFLlatpppgGDGAVPPPTSlaidpdhpvarriaaGAHGGLLTLERSWNEkgkrlrt 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  89 --SVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKR 166
Cdd:PRK07471 120 viTVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKLRLRP 199
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 496385745 167 IQIEDIQnhlrKIADKEGIQYEDDALFLVAQKADG----ALR----DALSIFDRLT 214
Cdd:PRK07471 200 LAPEDVI----DALAAAGPDLPDDPRAALAALAEGsvgrALRlaggDGLALYRRLT 251
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
20-161 1.04e-15

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 73.72  E-value: 1.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  20 VGQSHITDTLEHAIDNNQLAqALLFCGPRGVGKTTCARILARKINEKSgasddtgfaFNIYELDAASNNSVDDIRELI-- 97
Cdd:cd00009    1 VGQEEAIEALREALELPPPK-NLLLYGPPGTGKTTLARAIANELFRPG---------APFLYLNASDLLEGLVVAELFgh 70
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496385745  98 ---DQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEE------PPAHAIFILATT--EKHKIIPTILSRCQI 161
Cdd:cd00009   71 flvRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNrpLLGDLDRALYDRLDI 145
PRK13341 PRK13341
AAA family ATPase;
8-247 2.80e-15

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 77.02  E-value: 2.80e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   8 ARKYRPLEFDTVVGQSHITDT---LEHAIDNNQLAqALLFCGPRGVGKTTCARILARKINeksgasddtgfAFNIYeLDA 84
Cdd:PRK13341  19 ADRLRPRTLEEFVGQDHILGEgrlLRRAIKADRVG-SLILYGPPGVGKTTLARIIANHTR-----------AHFSS-LNA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  85 ASnNSVDDIRELIDQVRFA-PQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEppAHAIFILATTEK--HKIIPTILSRCQI 161
Cdd:PRK13341  86 VL-AGVKDLRAEVDRAKERlERHGKRTILFIDEVHRFNKAQQDALLPWVEN--GTITLIGATTENpyFEVNKALVSRSRL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 162 YDFKRIQIEDIQNHL-RKIADKEG------IQYEDDALFLVAQKADGalrDALSIFDRL-----TTFTQRN----ITLAK 225
Cdd:PRK13341 163 FRLKSLSDEDLHQLLkRALQDKERgygdrkVDLEPEAEKHLVDVANG---DARSLLNALelaveSTPPDEDglidITLAI 239
                        250       260
                 ....*....|....*....|....*....
gi 496385745 226 AAETL--NILDYD-----YYLQIADFAKS 247
Cdd:PRK13341 240 AEESIqqRAVLYDkegdaHFDTISAFIKS 268
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
22-165 3.13e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 75.38  E-value: 3.13e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  22 QSHITDTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKInekSGASDDTGFAFNIYELDAAS------------NNS 89
Cdd:PRK08769   9 QQRAYDQTVAALDAGRLGHGLLICGPEGLGKRAVALALAEHV---LASGPDPAAAQRTRQLIAAGthpdlqlvsfipNRT 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  90 VDDIRE--LIDQVR-------FAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
Cdd:PRK08769  86 GDKLRTeiVIEQVReisqklaLTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQ 165

                 ....*
gi 496385745 161 IYDFK 165
Cdd:PRK08769 166 RLEFK 170
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
89-187 3.73e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 74.83  E-value: 3.73e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  89 SVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYdfkRIQ 168
Cdd:PRK05917  76 SIETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLSI---HIP 152
                         90
                 ....*....|....*....
gi 496385745 169 IEDiqnhlRKIADKEGIQY 187
Cdd:PRK05917 153 MEE-----KTLVSKEDIAY 166
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
59-176 4.25e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 74.76  E-value: 4.25e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  59 LARKINEKSGASDDTGFAFNIYELDAASNN-SVDDIRELIDQVRFAPQV-GKYKVYIIDEVHMLSTAAFNAFLKTLEEPP 136
Cdd:PRK07132  39 LNKFNNLQITNLNEQELPANIILFDIFDKDlSKSEFLSAINKLYFSSFVqSQKKILIIKNIEKTSNSLLNALLKTIEEPP 118
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 496385745 137 AHAIFILATTEKHKIIPTILSRCQIYDFKRIQIEDIQNHL 176
Cdd:PRK07132 119 KDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILAKL 158
PRK04132 PRK04132
replication factor C small subunit; Provisional
47-250 4.48e-15

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 76.80  E-value: 4.48e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  47 PRGVGKTTCARILARKINEKSgasddtgFAFNIYELDAASNNSVDDIRELIDQVRFAPQVG--KYKVYIIDEVHMLSTAA 124
Cdd:PRK04132 574 PTVLHNTTAALALARELFGEN-------WRHNFLELNASDERGINVIREKVKEFARTKPIGgaSFKIIFLDEADALTQDA 646
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 125 FNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALR 204
Cdd:PRK04132 647 QQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 726
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 496385745 205 DALsifdrlttftqrNITLAKAAETLNILDYDYYLqIADFAKSNDI 250
Cdd:PRK04132 727 RAI------------NILQAAAALDDKITDENVFL-VASRARPEDI 759
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
27-160 1.39e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 73.68  E-value: 1.39e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  27 DTLEHAIDNNQLAQALLFCGPRGVGKTTCARILARKINEKSGASDDTGFAFNIyELDAASNN---------------SVD 91
Cdd:PRK06090  13 QNWKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQSEACGFCHSC-ELMQSGNHpdlhvikpekegksiTVE 91
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 496385745  92 DIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
Cdd:PRK06090  92 QIRQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQ 160
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
37-213 1.08e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 71.33  E-value: 1.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  37 QLAQALLFCGPRGVGKTTCARILARKI--------------------------------------NEKSGASDDTGFAfn 78
Cdd:PRK06964  19 RLPHALLLHGQAGIGKLDFAQHLAQGLlcetpqpdgepcgtcaacnwfaqgnhpdyrivrpealaAEAPGAADEAKEA-- 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  79 iyELDAASNNS--------VDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHK 150
Cdd:PRK06964  97 --DADEGGKKTkapskeikIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDR 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 151 IIPTILSRCQIYDFKRIQIEDIQNHLRK--IADKEGI---------------QYEDDAL--FLVAQKADGALRDALSIFD 211
Cdd:PRK06964 175 LLPTILSRCRQFPMTVPAPEAAAAWLAAqgVADADALlaeaggaplaalalaSDENRPLrdWTLGQLAAGAACDAFACAE 254

                 ..
gi 496385745 212 RL 213
Cdd:PRK06964 255 TL 256
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
90-162 1.64e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 70.53  E-value: 1.64e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 496385745  90 VDDIRELIDQV-RFAPQVGKYKVYIiDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIY 162
Cdd:PRK06871  89 VDQVREINEKVsQHAQQGGNKVVYI-QGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTW 161
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
42-161 6.37e-12

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 62.23  E-value: 6.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   42 LLFCGPRGVGKTTCARILARKINeksgasddtgfaFNIYELDAAS------NNSVDDIRELIDQVRF-APqvgkyKVYII 114
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELG------------APFIEISGSElvskyvGESEKRLRELFEAAKKlAP-----CVIFI 63
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496385745  115 DEVHMLSTA-----------AFNAFLKTLEEPPAHA---IFILATTEKHKIIPTILSRCQI 161
Cdd:pfam00004  64 DEIDALAGSrgsggdsesrrVVNQLLTELDGFTSSNskvIVIAATNRPDKLDPALLGRFDR 124
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
90-162 1.79e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 64.32  E-value: 1.79e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 496385745  90 VDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIY 162
Cdd:PRK07993  90 VDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCRLH 162
holA TIGR01128
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) ...
59-347 3.22e-09

DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273455 [Multi-domain]  Cd Length: 302  Bit Score: 57.27  E-value: 3.22e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   59 LARKINEKSGASDDTGFAFNIYELDAAsnnsvdDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAA-FNAFLKTLEEPPA 137
Cdd:TIGR01128   3 AADAIRAAALAQGFDEFNVFRIDGEEF------DWNQLLEEAQTLPLFSERRLVELRNPEGKPGAKgLKALEEYLANPPP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  138 HAIFILAT---TEKHKIIPT--ILSRCQIYDFKRIQIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDR 212
Cdd:TIGR01128  77 DTLLLIEApklDKRKKLTKWlkALKNAEIVECKTPKEQELPRWIQARLKKLGLRIDPDAVQLLAELVEGNLLAIAQELEK 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  213 LTTFTQ-RNITLAKAAETLNI-LDYDYYlQIADFAKSNDIPGILSKLNEIVNKGFDPHIFIGGLGSHFRDLM----MAQN 286
Cdd:TIGR01128 157 LALYAPdGKITLEDVEEAVSDsARFNVF-DLTDALLEGKAARALRILKGLLGEGEEPLILLALLQRQLRLLLqlkrLAQQ 235
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 496385745  287 PNTINLI----EVGEKTKAKYVEQSQKWTAQELIDALEICNQADINYKNSKNQ--RLTVEIALMQLA 347
Cdd:TIGR01128 236 GGPLAQLasklGIWPYRRKLALKALRRLSLAKLEQALQELAEADLQLKGTGGGdpWLALERLLLKLA 302
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
16-224 4.01e-09

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 56.43  E-value: 4.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  16 FDTVVGQSHITDTLEHAIDNNQLAQAL-----------LFCGPRGVGKTTCARILARKineksgasddTGFAFNIYELDA 84
Cdd:COG1223    1 LDDVVGQEEAKKKLKLIIKELRRRENLrkfglwpprkiLFYGPPGTGKTMLAEALAGE----------LKLPLLTVRLDS 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  85 ASNNSVDD----IRELIDQVRFAPQvgkykVYIIDEVHMLST------------AAFNAFLKTLEEPPAHAIFILATTEK 148
Cdd:COG1223   71 LIGSYLGEtarnLRKLFDFARRAPC-----VIFFDEFDAIAKdrgdqndvgevkRVVNALLQELDGLPSGSVVIAATNHP 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 149 HKIIPTILSRCQIydfkRIQI-----EDIQNHLRKIADKEGIQYEDDaLFLVAQKADG--------ALRDAL--SIFDRL 213
Cdd:COG1223  146 ELLDSALWRRFDE----VIEFplpdkEERKEILELNLKKFPLPFELD-LKKLAKKLEGlsgadiekVLKTALkkAILEDR 220
                        250
                 ....*....|.
gi 496385745 214 TTFTQRNITLA 224
Cdd:COG1223  221 EKVTKEDLEEA 231
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
90-165 2.37e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 53.50  E-value: 2.37e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496385745  90 VDDIRELIDQVRFAPqvgKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFK 165
Cdd:PRK08485  39 IEDAKEVIAEAYIAE---SEEKIIVIAAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRK 111
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
40-162 3.33e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 51.99  E-value: 3.33e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745    40 QALLFCGPRGVGKTTCARILARKINEKSG-----------ASDDTGFAFNIYELDAASNNSVDDIRELIDQVRfapqVGK 108
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGPPGGgviyidgedilEEVLDQLLLIIVGGKKASGSGELRLRLALALAR----KLK 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496385745   109 YKVYIIDEVHMLSTAAFNA--------FLKTLEEPPAHAIFILATTEKHKIIPTIL---SRCQIY 162
Cdd:smart00382  79 PDVLILDEITSLLDAEQEAllllleelRLLLLLKSEKNLTVILTTNDEKDLGPALLrrrFDRRIV 143
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
91-166 4.56e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 53.87  E-value: 4.56e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496385745  91 DDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIYDFKR 166
Cdd:PRK07276  87 DTIRELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFPK 162
AAA_22 pfam13401
AAA domain;
36-144 1.05e-07

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 50.03  E-value: 1.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   36 NQLAQALLFCGPRGVGKTTCARILARKINEK---------SGASDDTGFAFNIYELDAASNNSVDDIRELIDQV-RFAPQ 105
Cdd:pfam13401   2 RFGAGILVLTGESGTGKTTLLRRLLEQLPEVrdsvvfvdlPSGTSPKDLLRALLRALGLPLSGRLSKEELLAALqQLLLA 81
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 496385745  106 VGKYKVYIIDEVHMLSTAAFNaFLKTLEEPPAHAI-FILA 144
Cdd:pfam13401  82 LAVAVVLIIDEAQHLSLEALE-ELRDLLNLSSKLLqLILV 120
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
7-201 1.71e-07

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 52.61  E-value: 1.71e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   7 SARKYRPLEFDTVVGQSHITDTLEHAID----NNQLAQA--------LLFCGPRGVGKTTCARILARKINeksgasddtg 74
Cdd:COG0464  147 ELLELREAILDDLGGLEEVKEELRELVAlplkRPELREEyglppprgLLLYGPPGTGKTLLARALAGELG---------- 216
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  75 faFNIYELDAAS-----------NnsvddIRELIDQVRFAPQVgkykVYIIDEVHML-----------STAAFNAFLKTL 132
Cdd:COG0464  217 --LPLIEVDLSDlvskyvgetekN-----LREVFDKARGLAPC----VLFIDEADALagkrgevgdgvGRRVVNTLLTEM 285
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 496385745 133 EEPPAHAIFILATTEKHKIIPTILSRCQI------YDFK-RIQIedIQNHLRKIADKEGIQYEDdalflVAQKADG 201
Cdd:COG0464  286 EELRSDVVVIAATNRPDLLDPALLRRFDEiiffplPDAEeRLEI--FRIHLRKRPLDEDVDLEE-----LAEATEG 354
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
16-234 2.73e-07

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 51.35  E-value: 2.73e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  16 FDT-VVGQShitdtlehaidnNQLAQA---------------LLFCGPRGVGKT-----TCARILARKINEK----SGAS 70
Cdd:COG0593    7 FDNfVVGPS------------NRLAHAaalavaewpgkaynpLFLYGGVGLGKThllhaIGNEALENNPGARvvylTAEE 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  71 DDTGFAfniyelDAASNNSVDDIRELIDQVRfapqvgkykVYIIDEVHMLSTAA---------FNAFLktleeppAHAIF 141
Cdd:COG0593   75 FTNDFI------NAIRNNTIEEFKEKYRSVD---------VLLIDDIQFLAGKEatqeeffhtFNALR-------EAGKQ 132
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 142 ILATTEKH-KIIPTILSR-------CQIYDFK------RIQIediqnhLRKIADKEGIQYEDDALFLVAQKADGALRDAL 207
Cdd:COG0593  133 IVLTSDRPpKELPGLEERlrsrlewGLVVDIQppdletRIAI------LRKKAADRGLELPDEVLEYLARRIERNVRELE 206
                        250       260       270
                 ....*....|....*....|....*....|
gi 496385745 208 SIFDRLT---TFTQRNITLAKAAETLNILD 234
Cdd:COG0593  207 GALNRLDayaLLTGRPITLELAREVLKDLL 236
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
85-159 2.79e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 51.38  E-value: 2.79e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496385745  85 ASNNSVDDIRELIDQVRFAPQVGKYKVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRC 159
Cdd:PRK06581  66 AKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSRC 140
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
12-236 1.12e-06

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 49.74  E-value: 1.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  12 RPLEFDTVVGQSHITDTLEHAIDNNQL-AQAL---LFCGPRGVGKTTCARILARKINEK----SG-----ASDDTGFAFN 78
Cdd:PRK00080  20 RPKSLDEFIGQEKVKENLKIFIEAAKKrGEALdhvLLYGPPGLGKTTLANIIANEMGVNiritSGpalekPGDLAAILTN 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  79 IYELDaasnnsvddirelidqVRFapqvgkykvyiIDEVHMLStaafnaflKTLEE------------------PPAHAI 140
Cdd:PRK00080 100 LEEGD----------------VLF-----------IDEIHRLS--------PVVEEilypamedfrldimigkgPAARSI 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745 141 ------FIL--ATTEKHKII-P-----TILSRCQIYDfkriqIEDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDA 206
Cdd:PRK00080 145 rldlppFTLigATTRAGLLTsPlrdrfGIVQRLEFYT-----VEELEKIVKRSARILGVEIDEEGALEIARRSRGTPRIA 219
                        250       260       270
                 ....*....|....*....|....*....|....
gi 496385745 207 LSIFDRLTTFTQRN----ITLAKAAETLNILDYD 236
Cdd:PRK00080 220 NRLLRRVRDFAQVKgdgvITKEIADKALDMLGVD 253
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
110-162 1.14e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 49.45  E-value: 1.14e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 496385745 110 KVYIIDEVHMLSTAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIY 162
Cdd:PRK05818  90 KIYIIYGIEKLNKQSANSLLKLIEEPPKNTYGIFTTRNENNILNTILSRCVQY 142
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
42-158 1.67e-06

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 47.28  E-value: 1.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  42 LLFCGPRGVGKTTCARILARKINEKSGASDDTGFAfniyelDAASNNSVDDIRELIDQVRFAPQVgkykVYIIDEVHMLS 121
Cdd:cd19481   29 ILLYGPPGTGKTLLAKALAGELGLPLIVVKLSSLL------SKYVGESEKNLRKIFERARRLAPC----ILFIDEIDAIG 98
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 496385745 122 ------------TAAFNAFLKTLEEPPA--HAIFILATTEKHKIIPTILSR 158
Cdd:cd19481   99 rkrdssgesgelRRVLNQLLTELDGVNSrsKVLVIAATNRPDLLDPALLRP 149
PRK04132 PRK04132
replication factor C small subunit; Provisional
10-52 7.33e-05

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 44.83  E-value: 7.33e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 496385745  10 KYRPLEFDTVVGQSHITDTLEHAIDNNQLAQaLLFCGPRGVGK 52
Cdd:PRK04132  12 KYRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGK 53
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
170-207 1.88e-04

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 39.05  E-value: 1.88e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 496385745 170 EDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDAL 207
Cdd:cd18140    4 EQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAI 41
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
42-134 1.90e-04

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 41.12  E-value: 1.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   42 LLFCGPRGVGKTTCARILARKINEKSgasddtgfaFNIYELDAASNnsvddIRELIDQVRFAPQVGKY------------ 109
Cdd:pfam07728   2 VLLVGPPGTGKTELAERLAAALSNRP---------VFYVQLTRDTT-----EEDLFGRRNIDPGGASWvdgplvraareg 67
                          90       100
                  ....*....|....*....|....*
gi 496385745  110 KVYIIDEVHMLSTAAFNAFLKTLEE 134
Cdd:pfam07728  68 EIAVLDEINRANPDVLNSLLSLLDE 92
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
24-120 2.70e-04

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 42.62  E-value: 2.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745  24 HITDTLEHAIDNNQlaqALLFCGPRGVGKTTCARILARKINEKsgasddtgfafnIY---ELDAASNNSVDDIRELIDqv 100
Cdd:COG1373    8 KILDKLLKLLDNRK---AVVITGPRQVGKTTLLKQLAKELENI------------LYinlDDPRLRALAEEDPDDLLE-- 70
                         90       100
                 ....*....|....*....|
gi 496385745 101 RFAPQVGKYKVYIIDEVHML 120
Cdd:COG1373   71 ALKELYPGKTYLFLDEIQRV 90
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
9-143 4.15e-04

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 42.14  E-value: 4.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   9 RKYRPLEFDTVVGQ--------SHITDTLEHAIDNNQLAQALLFcGPRGVGKTTCARILARKINEksgASDDTGFAFNIY 80
Cdd:COG1474   14 RDREVLSPDYVPDRlphreeeiEELASALRPALRGERPSNVLIY-GPTGTGKTAVAKYVLEELEE---EAEERGVDVRVV 89
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 496385745  81 ELDAASNNSVDDI-RELIDQVRFAPQV---GkykvyiidevhmLSTAA-FNAFLKTLEEPPAHAIFIL 143
Cdd:COG1474   90 YVNCRQASTRYRVlSRILEELGSGEDIpstG------------LSTDElFDRLYEALDERDGVLVVVL 145
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
42-97 1.06e-03

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 37.97  E-value: 1.06e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 496385745   42 LLFCGPRGVGKTTCARILARKINEKSGASDDTGFAFN---------------IYElDAASNNSVDDIRELI 97
Cdd:pfam00910   1 IWLYGPPGCGKSTLAKYLARALLKKLGLPKDSVYSRNpdddfwdgytgqpvvIID-DFGQNPDGPDEAELI 70
RecA-like_ClpB_Hsp104-like cd19499
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ...
10-64 3.11e-03

Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410907 [Multi-domain]  Cd Length: 178  Bit Score: 37.93  E-value: 3.11e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 496385745  10 KYRPLE---FDTVVGQSHITDTLEHAIdnnQLAQA-----------LLFCGPRGVGKTTCARILARKIN 64
Cdd:cd19499    1 KLLNLEerlHERVVGQDEAVKAVSDAI---RRARAglsdpnrpigsFLFLGPTGVGKTELAKALAELLF 66
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
170-213 4.08e-03

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 35.52  E-value: 4.08e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 496385745 170 EDIQNHLRKIADKEGIQYEDDALFLVAQKADGALRDALSIFDRL 213
Cdd:cd18133    4 EQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRA 47
AAA_7 pfam12775
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 ...
17-119 7.52e-03

P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 proteins. Cytoplasmic dynein-2 (dynein-2) performs intraflagellar transport and is associated with human skeletal ciliopathies. Dyneins share a conserved motor domain that couples cycles of ATP hydrolysis with conformational changes to produce movement. Structural analysis reveal that the motor's ring consists of six AAA+ domains (ATPases associated with various cellular activities (AAA1-AAA6). This is the third nucleotide binding sites in the dynein motor. However, AAA3 has lost the catalytic residues necessary for ATP hydrolysis (the Walker B glutamate, the arginine finger, sensor-I and sensor-II motifs).


Pssm-ID: 463698 [Multi-domain]  Cd Length: 179  Bit Score: 36.99  E-value: 7.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496385745   17 DTVVgQSHITDTLehaIDNNQlaqALLFCGPRGVGKTTCarilarkINEKSGASDDTGFAFNIYELDAASnnSVDDIREL 96
Cdd:pfam12775  16 DTVR-YTYLLDLL---LKNGK---PVLLVGPTGTGKTVI-------IQNLLRKLDKEKYLPLFINFSAQT--TSNQTQDI 79
                          90       100       110
                  ....*....|....*....|....*....|
gi 496385745   97 IDQ-------VRFAPQVGKYKVYIIDEVHM 119
Cdd:pfam12775  80 IESklekrrkGVYGPPGGKKLVVFIDDLNM 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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