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Conserved domains on  [gi|497391985|ref|WP_009706198|]
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MULTISPECIES: helix-turn-helix transcriptional regulator [Vibrio]

Protein Classification

ArsR/SmtB family transcription factor( domain architecture ID 10001925)

ArsR (Arsenical Resistance Operon Repressor)/SmtB family transcription factor is a winged-helix-turn-helix transcriptional regulator that may be metal-sensing and modulate the expression of genes associated with metal homeostasis

Gene Ontology:  GO:0003700|GO:0006355|GO:0003677
PubMed:  10473770|28436329|12829264|28512703|30191942|15808743

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
21-104 1.01e-21

DNA-binding transcriptional regulator, ArsR family [Transcription];


:

Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 81.86  E-value: 1.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497391985  21 EKEQTLAAQAKALSHPARLRILHILHTldtmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRIQRDA 100
Cdd:COG0640    5 KELEELAELFKALADPTRLRILRLLAE----GELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRREGRWVYYRLADEA 80


                 ....
gi 497391985 101 FDQF 104
Cdd:COG0640   81 LAEL 84
 
Name Accession Description Interval E-value
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
21-104 1.01e-21

DNA-binding transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 81.86  E-value: 1.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497391985  21 EKEQTLAAQAKALSHPARLRILHILHTldtmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRIQRDA 100
Cdd:COG0640    5 KELEELAELFKALADPTRLRILRLLAE----GELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRREGRWVYYRLADEA 80


                 ....
gi 497391985 101 FDQF 104
Cdd:COG0640   81 LAEL 84
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 30-96 4.58e-17

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 69.63  E-value: 4.58e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497391985  30 AKALSHPARLRILHILHTldtmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRI 96
Cdd:cd00090    1 LKALSDPTRLRILRLLLE----GPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRREGRRVYYSL 63
HTH_metalloreg NF033788
metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense ...
 31-103 2.41e-16

metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.


Pssm-ID: 411368 [Multi-domain]  Cd Length: 76  Bit Score: 67.49  E-value: 2.41e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497391985  31 KALSHPARLRILHILHTldtmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRIQRDAFDQ 103
Cdd:NF033788   6 KALADPTRLRILELLAE----GELCVCELAEALGLSQSAVSQHLKVLRDAGLVTSRREGRWVYYRLADEHVAE 74
HTH_20 pfam12840
Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in ...
 27-83 1.08e-10

Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.


Pssm-ID: 432824 [Multi-domain]  Cd Length: 61  Bit Score: 52.93  E-value: 1.08e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 497391985   27 AAQAKALSHPARLRILHILHTLDTMggcLNSDLVSELGLAQSTVSEHLRILKQAGFI 83
Cdd:pfam12840   1 DDVAEALADPTRLRILRALVGDEPL---TASELARRLDISRNTLSYHLRKLEEAGLV 54
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
40-104 1.85e-10

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 52.21  E-value: 1.85e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497391985    40 RILHILHtldtMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRIQRDAFDQF 104
Cdd:smart00418   1 KILKLLA----EGELCVCELAEILGLSQSTVSHHLKKLREAGLVESRREGKRVYYSLTDEKVADL 61
cas_HTH TIGR01884
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ...
 42-94 1.12e-04

CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]


Pssm-ID: 273852 [Multi-domain]  Cd Length: 203  Bit Score: 39.26  E-value: 1.12e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 497391985   42 LHILHTLDTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCY 94
Cdd:TIGR01884 146 LKILEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLVEQKGRKGKRYS 198
 
Name Accession Description Interval E-value
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
21-104 1.01e-21

DNA-binding transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 81.86  E-value: 1.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497391985  21 EKEQTLAAQAKALSHPARLRILHILHTldtmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRIQRDA 100
Cdd:COG0640    5 KELEELAELFKALADPTRLRILRLLAE----GELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRREGRWVYYRLADEA 80


                 ....
gi 497391985 101 FDQF 104
Cdd:COG0640   81 LAEL 84
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 30-96 4.58e-17

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 69.63  E-value: 4.58e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497391985  30 AKALSHPARLRILHILHTldtmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRI 96
Cdd:cd00090    1 LKALSDPTRLRILRLLLE----GPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRREGRRVYYSL 63
HTH_metalloreg NF033788
metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense ...
 31-103 2.41e-16

metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.


Pssm-ID: 411368 [Multi-domain]  Cd Length: 76  Bit Score: 67.49  E-value: 2.41e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497391985  31 KALSHPARLRILHILHTldtmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRIQRDAFDQ 103
Cdd:NF033788   6 KALADPTRLRILELLAE----GELCVCELAEALGLSQSAVSQHLKVLRDAGLVTSRREGRWVYYRLADEHVAE 74
COG4189 COG4189
Predicted transcriptional regulator, ArsR family [Transcription];
26-95 2.36e-15

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 443343 [Multi-domain]  Cd Length: 97  Bit Score: 65.75  E-value: 2.36e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497391985  26 LAAQAKALSHPARLRILHILHTldtmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNP-----PKVCYR 95
Cdd:COG4189    9 SLEVLKALASETRLRILRLLAE----EPLNVNELAEALGLPKSTVSYHIRKLEEAGLIRTEYKPgkrgrQKICYL 79
COG3398 COG3398
Predicted transcriptional regulator, contains two HTH domains [Transcription];
21-100 5.95e-11

Predicted transcriptional regulator, contains two HTH domains [Transcription];


Pssm-ID: 442625 [Multi-domain]  Cd Length: 159  Bit Score: 55.65  E-value: 5.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497391985  21 EKEQTLAAqakALSHPARLRIL-HILHtldtMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRIQRD 99
Cdd:COG3398   85 EEEKKILA---YLRRETPRRILlYLLE----NPGATNKELAEELGISRSTVSWHLKRLEEDGLVERERDGRNVRYYLNPP 157


                 .
gi 497391985 100 A 100
Cdd:COG3398  158 E 158
HTH_20 pfam12840
Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in ...
 27-83 1.08e-10

Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.


Pssm-ID: 432824 [Multi-domain]  Cd Length: 61  Bit Score: 52.93  E-value: 1.08e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 497391985   27 AAQAKALSHPARLRILHILHTLDTMggcLNSDLVSELGLAQSTVSEHLRILKQAGFI 83
Cdd:pfam12840   1 DDVAEALADPTRLRILRALVGDEPL---TASELARRLDISRNTLSYHLRKLEEAGLV 54
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
40-104 1.85e-10

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 52.21  E-value: 1.85e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497391985    40 RILHILHtldtMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRIQRDAFDQF 104
Cdd:smart00418   1 KILKLLA----EGELCVCELAEILGLSQSTVSHHLKKLREAGLVESRREGKRVYYSLTDEKVADL 61
HTH_5 pfam01022
Bacterial regulatory protein, arsR family; Members of this family contains a DNA binding ...
 35-83 7.81e-10

Bacterial regulatory protein, arsR family; Members of this family contains a DNA binding 'helix-turn-helix' motif. This family includes other proteins which are not included in the Prosite definition.


Pssm-ID: 425993 [Multi-domain]  Cd Length: 45  Bit Score: 50.13  E-value: 7.81e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 497391985   35 HPARLRILHILHTldtmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFI 83
Cdd:pfam01022   1 DPTRLKILKLLAE----GELCVCELAEELGLSQSTVSHHLKKLREAGLV 45
COG1777 COG1777
Predicted transcriptional regulator, ArsR family [Transcription];
26-96 1.10e-08

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441383  Cd Length: 113  Bit Score: 48.88  E-value: 1.10e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497391985  26 LAAQAKALSHPARLRILHILhtldTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISA-----EPNPPKVCYRI 96
Cdd:COG1777    7 LDRLLDALGNPTRRRILALL----SEEPAYVSELARELGVSRQAVYKHLRKLEEAGLVESyregrEDGRARKYYRL 78
MarR pfam01047
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 42-89 5.08e-08

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 426012 [Multi-domain]  Cd Length: 59  Bit Score: 46.00  E-value: 5.08e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 497391985   42 LHILHTLDTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNP 89
Cdd:pfam01047   6 FHILRILYEHGPLTVSELAEKLGVSKSTVTRVLDRLEKKGLIERSRSP 53
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 44-89 4.05e-05

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 38.34  E-value: 4.05e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 497391985   44 ILHTLDTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNP 89
Cdd:pfam12802  10 VLLALARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLVEREPSP 55
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
42-89 5.38e-05

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 39.11  E-value: 5.38e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 497391985    42 LHILHTLDTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNP 89
Cdd:smart00347  13 FLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRREPSP 60
CasRa_I-A cd09655
CRISPR/Cas system-associated transcriptional regulator CasRa; CRISPR (Clustered Regularly ...
 42-94 5.41e-05

CRISPR/Cas system-associated transcriptional regulator CasRa; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Predicted transcriptional regulator of CRISPR/Cas system


Pssm-ID: 187786 [Multi-domain]  Cd Length: 198  Bit Score: 40.44  E-value: 5.41e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 497391985  42 LHILHTLDTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCY 94
Cdd:cd09655  142 LKILEVLKAKGEKSVKNIAKKLGKSLSTISRHLRELEKKGLVEQKGTKGKRYS 194
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
1-89 6.14e-05

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 39.57  E-value: 6.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497391985   1 MSDKCNDTCEVVFQT---TQQQLEKEQTLAAQAKALSHPArlriLHILHTLDTMGGCLNSDLVSELGLAQSTVSEHLRIL 77
Cdd:COG1846    1 MSDEPDPAEERLGLLlrrLARALRRALDRALAELGLTPAQ----FRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRL 76

                         90
                 ....*....|..
gi 497391985  78 KQAGFISAEPNP 89
Cdd:COG1846   77 EEKGLVEREPDP 88
cas_HTH TIGR01884
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ...
 42-94 1.12e-04

CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]


Pssm-ID: 273852 [Multi-domain]  Cd Length: 203  Bit Score: 39.26  E-value: 1.12e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 497391985   42 LHILHTLDTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCY 94
Cdd:TIGR01884 146 LKILEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLVEQKGRKGKRYS 198
Lrp COG1522
DNA-binding transcriptional regulator, Lrp family [Transcription];
39-104 3.22e-04

DNA-binding transcriptional regulator, Lrp family [Transcription];


Pssm-ID: 441131 [Multi-domain]  Cd Length: 138  Bit Score: 37.45  E-value: 3.22e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497391985  39 LRILHILHTLDTMGgclNSDLVSELGLAQSTVSEHLRILKQAGFI---SAEPNPPKVCYRIQ--------RDAFDQF 104
Cdd:COG1522    8 RRILRLLQEDGRLS---FAELAERVGLSESTVLRRVRRLEEAGVIrgyGAVVDPEKLGLGVTafvevkvpPHRLDEF 81
IclR COG1414
DNA-binding transcriptional regulator, IclR family [Transcription];
40-87 3.59e-04

DNA-binding transcriptional regulator, IclR family [Transcription];


Pssm-ID: 441024 [Multi-domain]  Cd Length: 253  Bit Score: 38.26  E-value: 3.59e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 497391985  40 RILHILHTLDTMGGCL-NSDLVSELGLAQSTVSEHLRILKQAGFISAEP 87
Cdd:COG1414   10 RALAILEALAEAGGGLsLSELARRLGLPKSTVHRLLATLEEEGYVERDP 58
HTH_24 pfam13412
Winged helix-turn-helix DNA-binding;
42-83 6.71e-04

Winged helix-turn-helix DNA-binding;


Pssm-ID: 404317 [Multi-domain]  Cd Length: 45  Bit Score: 34.72  E-value: 6.71e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 497391985   42 LHILHTLDTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFI 83
Cdd:pfam13412   4 RKILNLLQENPRISQRELAERLGLSPSTVNRRLKRLEEEGVI 45
HTH_CRP cd00092
helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic ...
 58-88 1.07e-03

helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family.


Pssm-ID: 238044 [Multi-domain]  Cd Length: 67  Bit Score: 34.95  E-value: 1.07e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 497391985  58 DLVSELGLAQSTVSEHLRILKQAGFISAEPN 88
Cdd:cd00092   30 EIADYLGLTRETVSRTLKELEEEGLISRRGR 60
HTH_IclR pfam09339
IclR helix-turn-helix domain;
40-87 3.22e-03

IclR helix-turn-helix domain;


Pssm-ID: 430539 [Multi-domain]  Cd Length: 52  Bit Score: 33.15  E-value: 3.22e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 497391985   40 RILHILHTLDTMGGCL-NSDLVSELGLAQSTVSEHLRILKQAGFISAEP 87
Cdd:pfam09339   4 RALAILDALAEAPGPLtLTEIARRTGLPKSTAHRLLQTLVELGYVEQDP 52
COG3432 COG3432
Predicted transcriptional regulator [Transcription];
38-96 4.48e-03

Predicted transcriptional regulator [Transcription];


Pssm-ID: 442658 [Multi-domain]  Cd Length: 83  Bit Score: 33.69  E-value: 4.48e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 497391985  38 RLRILH-ILHTLDTmGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEPNPPKVCYRI 96
Cdd:COG3432    6 RLEIIAdILEALKN-EGAKKTRIMYKANLSYDRLKKYLDLLEEKGLIEKEDDGGRRIYRI 64
MntR COG1321
Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];
44-87 5.09e-03

Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];


Pssm-ID: 440932 [Multi-domain]  Cd Length: 135  Bit Score: 34.41  E-value: 5.09e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 497391985  44 ILHTLDTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAEP 87
Cdd:COG1321   15 IYELSEEGGPVRTSDIAERLGVSPPSVTEMLKKLEEKGLVEYEP 58
COG2512 COG2512
Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain ...
 40-86 6.45e-03

Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain [General function prediction only];


Pssm-ID: 442002 [Multi-domain]  Cd Length: 80  Bit Score: 32.96  E-value: 6.45e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 497391985  40 RILHILhtLDTMGGCLNSDLVSELGLAQSTVSEHLRILKQAGFISAE 86
Cdd:COG2512   19 RVLELL--RENGGRMTQSEIVKETGWSKSKVSRLLSRLEERGLIEKE 63
HTH_CRP smart00419
helix_turn_helix, cAMP Regulatory protein;
58-86 6.54e-03

helix_turn_helix, cAMP Regulatory protein;


Pssm-ID: 128696 [Multi-domain]  Cd Length: 48  Bit Score: 32.41  E-value: 6.54e-03
                           10        20
                   ....*....|....*....|....*....
gi 497391985    58 DLVSELGLAQSTVSEHLRILKQAGFISAE 86
Cdd:smart00419  13 EIAELLGLTRETVSRTLKRLEKEGLISRE 41
DmsR COG3413
Predicted transcriptional regulator, contains HTH domain [General function prediction only];
57-75 7.17e-03

Predicted transcriptional regulator, contains HTH domain [General function prediction only];


Pssm-ID: 442639 [Multi-domain]  Cd Length: 143  Bit Score: 33.76  E-value: 7.17e-03
                         10
                 ....*....|....*....
gi 497391985  57 SDLVSELGLAQSTVSEHLR 75
Cdd:COG3413  112 EELAEELGISKSTLSEHLR 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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