|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-429 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 936.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 1 MPFIQHVYAREVLDSRGNPTVEVEVLTESGFFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAII 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 81 GMDVTDQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 161 DFQEFMILPVGAPTFKEAIRMGAEVFHALKKVLSGKGLNTAVGDEGGFAPNLGSNREALEVIIEAIKSAGYEPGKDILLG 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 241 MDVASSEFYnkETGKYDLAGEGRTgLSSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLLTDRIGGKVQLVGDDLFVT 320
Cdd:COG0148 241 LDVAASEFY--KDGKYHLKGEGKE-LTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVT 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 321 NTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDR 400
Cdd:COG0148 318 NPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSER 397
|
410 420
....*....|....*....|....*....
gi 497478881 401 IAKYNQLLRIEDELGDLAVYDGLKSFYNL 429
Cdd:COG0148 398 VAKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-430 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 907.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 1 MPFIQHVYAREVLDSRGNPTVEVEVLTESGFFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAII 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 81 GMDVTDQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 161 DFQEFMILPVGAPTFKEAIRMGAEVFHALKKVLSGKGLNTAVGDEGGFAPNLGSNREALEVIIEAIKSAGYEPGKDILLG 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 241 MDVASSEFYnkETGKYDLAGEGRTglsSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLLTDRIGGKVQLVGDDLFVT 320
Cdd:PRK00077 241 LDCAASEFY--KDGKYVLEGEGLT---SEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVT 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 321 NTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDR 400
Cdd:PRK00077 316 NTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 395
|
410 420 430
....*....|....*....|....*....|
gi 497478881 401 IAKYNQLLRIEDELGDLAVYDGLKSFYNLK 430
Cdd:PRK00077 396 IAKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-429 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 782.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 4 IQHVYAREVLDSRGNPTVEVEVLTESGFFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAIIGMD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 84 VTDQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNVDFQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 164 EFMILPVGAPTFKEAIRMGAEVFHALKKVLSGKGLNTAVGDEGGFAPNLGSNREALEVIIEAIKSAGYEPGKDILLGMDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 244 ASSEFYNKETGKYDLAGEGRTgLSSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLLTDRIGGKVQLVGDDLFVTNTK 323
Cdd:TIGR01060 241 AASEFYDEEDGKYVYKGENKQ-LTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 324 KLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDRIAK 403
Cdd:TIGR01060 320 ILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 399
|
410 420
....*....|....*....|....*.
gi 497478881 404 YNQLLRIEDELGDLAVYDGLKSFYNL 429
Cdd:TIGR01060 400 YNQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
7-413 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 780.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 7 VYAREVLDSRGNPTVEVEVLTESGFFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAIIGMDVTD 86
Cdd:cd03313 2 IKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVTD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 87 QVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNVDFQEFM 166
Cdd:cd03313 82 QRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEFM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 167 ILPVGAPTFKEAIRMGAEVFHALKKVLSGKG--LNTAVGDEGGFAPNLGSNREALEVIIEAIKSAGYEPGKDILLGMDVA 244
Cdd:cd03313 162 IVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 245 SSEFYNKETGKYDLAGEGRtgLSSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLLTDRIGGKVQLVGDDLFVTNTKK 324
Cdd:cd03313 242 ASEFYDEGKYVYDSDEGKK--LTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 325 LAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDRIAKY 404
Cdd:cd03313 320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399
|
....*....
gi 497478881 405 NQLLRIEDE 413
Cdd:cd03313 400 NQLLRIEEE 408
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
142-429 |
2.81e-171 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 481.59 E-value: 2.81e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 142 LPTPMMNIINGGSHADNNVDFQEFMILPVGAPTFKEAIRMGAEVFHALKKVLSGKG--LNTAVGDEGGFAPNLGSNREAL 219
Cdd:pfam00113 4 LPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKEAL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 220 EVIIEAIKSAGYEPgkDILLGMDVASSEFYNKETGKYDLAGEGRTG-----LSSEDMVNFYEELVNEFPILSIEDGLDEN 294
Cdd:pfam00113 84 DLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGEKSdkskkLTSAQLADLYEELVKKYPIVSIEDPFDED 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 295 DWEGHKLLTDRIGGKVQLVGDDLFVTNTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETE 374
Cdd:pfam00113 162 DWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETE 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 497478881 375 DATIADIAVATNAGQIKTGSMSRTDRIAKYNQLLRIEDELGDLAVYDGLKSFYNL 429
Cdd:pfam00113 242 DTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-429 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 936.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 1 MPFIQHVYAREVLDSRGNPTVEVEVLTESGFFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAII 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 81 GMDVTDQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 161 DFQEFMILPVGAPTFKEAIRMGAEVFHALKKVLSGKGLNTAVGDEGGFAPNLGSNREALEVIIEAIKSAGYEPGKDILLG 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 241 MDVASSEFYnkETGKYDLAGEGRTgLSSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLLTDRIGGKVQLVGDDLFVT 320
Cdd:COG0148 241 LDVAASEFY--KDGKYHLKGEGKE-LTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVT 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 321 NTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDR 400
Cdd:COG0148 318 NPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSER 397
|
410 420
....*....|....*....|....*....
gi 497478881 401 IAKYNQLLRIEDELGDLAVYDGLKSFYNL 429
Cdd:COG0148 398 VAKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-430 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 907.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 1 MPFIQHVYAREVLDSRGNPTVEVEVLTESGFFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAII 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 81 GMDVTDQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 161 DFQEFMILPVGAPTFKEAIRMGAEVFHALKKVLSGKGLNTAVGDEGGFAPNLGSNREALEVIIEAIKSAGYEPGKDILLG 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 241 MDVASSEFYnkETGKYDLAGEGRTglsSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLLTDRIGGKVQLVGDDLFVT 320
Cdd:PRK00077 241 LDCAASEFY--KDGKYVLEGEGLT---SEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVT 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 321 NTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDR 400
Cdd:PRK00077 316 NTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 395
|
410 420 430
....*....|....*....|....*....|
gi 497478881 401 IAKYNQLLRIEDELGDLAVYDGLKSFYNLK 430
Cdd:PRK00077 396 IAKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-429 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 782.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 4 IQHVYAREVLDSRGNPTVEVEVLTESGFFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAIIGMD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 84 VTDQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNVDFQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 164 EFMILPVGAPTFKEAIRMGAEVFHALKKVLSGKGLNTAVGDEGGFAPNLGSNREALEVIIEAIKSAGYEPGKDILLGMDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 244 ASSEFYNKETGKYDLAGEGRTgLSSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLLTDRIGGKVQLVGDDLFVTNTK 323
Cdd:TIGR01060 241 AASEFYDEEDGKYVYKGENKQ-LTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 324 KLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDRIAK 403
Cdd:TIGR01060 320 ILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 399
|
410 420
....*....|....*....|....*.
gi 497478881 404 YNQLLRIEDELGDLAVYDGLKSFYNL 429
Cdd:TIGR01060 400 YNQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
7-413 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 780.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 7 VYAREVLDSRGNPTVEVEVLTESGFFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAIIGMDVTD 86
Cdd:cd03313 2 IKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVTD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 87 QVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNVDFQEFM 166
Cdd:cd03313 82 QRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEFM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 167 ILPVGAPTFKEAIRMGAEVFHALKKVLSGKG--LNTAVGDEGGFAPNLGSNREALEVIIEAIKSAGYEPGKDILLGMDVA 244
Cdd:cd03313 162 IVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 245 SSEFYNKETGKYDLAGEGRtgLSSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLLTDRIGGKVQLVGDDLFVTNTKK 324
Cdd:cd03313 242 ASEFYDEGKYVYDSDEGKK--LTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 325 LAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDRIAKY 404
Cdd:cd03313 320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399
|
....*....
gi 497478881 405 NQLLRIEDE 413
Cdd:cd03313 400 NQLLRIEEE 408
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
1-422 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 622.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 1 MPFIQHVYAREVLDSRGNPTVEVEVLTESGFFgRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAII 80
Cdd:PTZ00081 1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 81 GMDVTDQVGIDRTMIE-LDGTEN-----KGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQ-----LPTPMMNI 149
Cdd:PTZ00081 80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKPtdkfvLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 150 INGGSHADNNVDFQEFMILPVGAPTFKEAIRMGAEVFHALKKVLSGK-GLN-TAVGDEGGFAPNLGSNREALEVIIEAIK 227
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLDaTNVGDEGGFAPNIKDPEEALDLLVEAIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 228 SAGYEpGKdILLGMDVASSEFYNKETGKYDL-----AGEGRTGLSSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLL 302
Cdd:PTZ00081 240 KAGYE-GK-VKICMDVAASEFYDKEKKVYDLdfknpNNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 303 TDRIGGKVQLVGDDLFVTNTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIA 382
Cdd:PTZ00081 318 TAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLV 397
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 497478881 383 VATNAGQIKTGSMSRTDRIAKYNQLLRIEDELGDLAVYDG 422
Cdd:PTZ00081 398 VGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
|
|
| PLN00191 |
PLN00191 |
enolase |
1-422 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 583.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 1 MPFIQHVYAREVLDSRGNPTVEVEVLTESGFFgRAIVPSGASTGEHEAVELRDGDKsRYLGKGVQNAVDNVNNLISEAII 80
Cdd:PLN00191 25 MATITKVKARQIIDSRGNPTVEVDLHTSKGMF-RAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 81 GMDVTDQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRY---LGGFNAKQLPTPMMNIINGGSHAD 157
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHiadLAGNKKLVLPVPAFNVINGGSHAG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 158 NNVDFQEFMILPVGAPTFKEAIRMGAEVFHALKKVLSGK--GLNTAVGDEGGFAPNLGSNREALEVIIEAIKSAGYEpGK 235
Cdd:PLN00191 183 NKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT-GK 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 236 dILLGMDVASSEFYNKEtGKYDL-----AGEGRTGLSSEDMVNFYEELVNEFPILSIEDGLDENDWEGHKLLTDRigGKV 310
Cdd:PLN00191 262 -IKIGMDVAASEFYTKD-KKYDLdfkeeNNDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--EDV 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 311 QLVGDDLFVTNTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQI 390
Cdd:PLN00191 338 QIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQI 417
|
410 420 430
....*....|....*....|....*....|..
gi 497478881 391 KTGSMSRTDRIAKYNQLLRIEDELGDLAVYDG 422
Cdd:PLN00191 418 KTGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
142-429 |
2.81e-171 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 481.59 E-value: 2.81e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 142 LPTPMMNIINGGSHADNNVDFQEFMILPVGAPTFKEAIRMGAEVFHALKKVLSGKG--LNTAVGDEGGFAPNLGSNREAL 219
Cdd:pfam00113 4 LPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKEAL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 220 EVIIEAIKSAGYEPgkDILLGMDVASSEFYNKETGKYDLAGEGRTG-----LSSEDMVNFYEELVNEFPILSIEDGLDEN 294
Cdd:pfam00113 84 DLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGEKSdkskkLTSAQLADLYEELVKKYPIVSIEDPFDED 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 295 DWEGHKLLTDRIGGKVQLVGDDLFVTNTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETE 374
Cdd:pfam00113 162 DWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETE 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 497478881 375 DATIADIAVATNAGQIKTGSMSRTDRIAKYNQLLRIEDELGDLAVYDGLKSFYNL 429
Cdd:pfam00113 242 DTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
4-134 |
1.12e-94 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 280.42 E-value: 1.12e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 4 IQHVYAREVLDSRGNPTVEVEVLTESGFFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVQNAVDNVNNLISEAIIGMD 83
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 497478881 84 VTDQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYL 134
Cdd:pfam03952 81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
1-416 |
3.93e-24 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 102.58 E-value: 3.93e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 1 MPFIQHVYAREVLDSRGNPTVEVEVLTESGFfGRAIVPSgastgeheavelrDGDKSRYLGKGvQNAVDNVNNLISEAII 80
Cdd:PRK08350 1 MTVIENIIGRVAVLRGGKYSVEVDVITDSGF-GRFAAPI-------------DENPSLYIAEA-HRAVSEVDEIIGPELI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 81 GMDVTDQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTPMMNIINggshaDNNV 160
Cdd:PRK08350 66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAE-----DENF 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 161 DFQEFM--ILPVgaptfkeairmgAEVFHALKKVLSgkglntavgdeggfapnlGSNREALEVIIEAIKSAGYEPGKDIL 238
Cdd:PRK08350 141 EYYVLVrdLMEI------------TDVVDAVNKILE------------------NSKEVSLEGLSKASEKAGDELGLEVA 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 239 LGMDVassefynketgkydlagegRTGLSSEDMVNfyeeLVNEFPILSIEDGLDEndweghKLLTDRIGGK--VQLVGDD 316
Cdd:PRK08350 191 LGIAQ-------------------KREMETEKVLN----LVEDNNIAYIKPIGDE------ELFLELIAGThgVFIDGEY 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 317 LFVTNTKklaqgIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIktgsMS 396
Cdd:PRK08350 242 LFRTRNI-----LDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAM----LI 312
|
410 420
....*....|....*....|
gi 497478881 397 RTDRIAKYNQLLRIEDELGD 416
Cdd:PRK08350 313 HKDSVEKINELNRIAEDLGE 332
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
193-392 |
1.13e-14 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 73.13 E-value: 1.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 193 LSGKGLNTAVGDEGGfapnlGSNREALEVI--IEAIKSAGYEPGKDILLGMDVASsefynketgkydlagegrtGLSSED 270
Cdd:cd00308 54 LAAKALGVPLAELLG-----GGSRDRVPAYgsIERVRAVREAFGPDARLAVDANG-------------------AWTPKE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 271 MVNFYEELvNEFPILSIEDGLDENDWEGHKLLTDRIGgkVQLVGDDLFVTNTKKLaQGIEQGVGNSILIKVNQIGTLTET 350
Cdd:cd00308 110 AIRLIRAL-EKYGLAWIEEPCAPDDLEGYAALRRRTG--IPIAADESVTTVDDAL-EALELGAVDILQIKPTRVGGLTES 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 497478881 351 FEAIEMAKRAGYTAVVSHRSG-ETEDATIADIAVAT-NAGQIKT 392
Cdd:cd00308 186 RRAADLAEAFGIRVMVHGTLEsSIGTAAALHLAAALpNDRAIET 229
|
|
| PTZ00378 |
PTZ00378 |
hypothetical protein; Provisional |
86-414 |
1.55e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 173571 [Multi-domain] Cd Length: 518 Bit Score: 56.42 E-value: 1.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 86 DQVGIDRTMIELDGTENKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGF-----NAKQLPTPMMNI--INGGSHADN 158
Cdd:PTZ00378 126 DQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLRALfgsltSVETFSMPQLCItfFGPGNPSTA 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 159 NVDFQEFMILPV---GApTFKEAIRMGAEVFHALKKVLsgkglNTAVGDEGGFAPNLGSN-REALEVIIEAIKSAGYEPG 234
Cdd:PTZ00378 206 RLALKSVLFSPVmpsGT-VLRERMQKIFAAFHHFCQSH-----NSSVRSDGSLHWDGFANlTDAVKLATEALRAVQLTPG 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 235 KDILLGMDVASSEFYNKETGKYDLA------GEGRTGLS--------SEDMVNFY-EELVNEFP--ILSIEDGLDENDWE 297
Cdd:PTZ00378 280 TDVCLGLRMAASTTRVPATAVADGGawkeakDDCEVLYSlfpgepdvTGDQLSEYvREQLQAVPdiVVYVEDTHCDEDTF 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 298 GHKLLTDRIGGKVQLVGDDLFV-TNTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKR-AGYTAVVSHRSGETED 375
Cdd:PTZ00378 360 GLQRLQAALGDSIVLSGVDVYArSEYKKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGEdEGRAVTVLVQTLAGNA 439
|
330 340 350
....*....|....*....|....*....|....*....
gi 497478881 376 ATIADIAVATNAGQIKTGSMSRTDRIAKYNQLLRIEDEL 414
Cdd:PTZ00378 440 ATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDEL 478
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
6-387 |
1.04e-07 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 53.67 E-value: 1.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 6 HVYAREVLDSRGNPTVEVEvlTESGFFGRaivpsgastGEheavelrdgdkSRYLGKGVQNAVDNVNNLISEAIIGMDVT 85
Cdd:COG4948 19 FTISRGTRTERDVVLVRVE--TDDGITGW---------GE-----------AVPGGTGAEAVAAALEEALAPLLIGRDPL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 86 DqvgIDRTMIELDgteNKGKLGANAILGVSMACAHAAAESVGLPLYRYLGGFNAKQLPTpmmniinGGSHADNNVD-FQE 164
Cdd:COG4948 77 D---IEALWQRLY---RALPGNPAAKAAVDMALWDLLGKALGVPVYQLLGGKVRDRVPV-------YATLGIDTPEeMAE 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 165 FMilpvgaptfKEAIRMGaevFHALK-KVlsgkglntavgdeGGFAPnlgsnREALEvIIEAIKSAGyepGKDILLGMDV 243
Cdd:COG4948 144 EA---------REAVARG---FRALKlKV-------------GGPDP-----EEDVE-RVRAVREAV---GPDARLRVDA 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 244 assefyNketgkydlagegrTGLSSEDMVNFYEELVnEFPILSIEDGLDENDWEGHKLLTDRIGgkVQLVGDDLfVTNTK 323
Cdd:COG4948 190 ------N-------------GAWTLEEAIRLLRALE-DLGLEWIEQPLPAEDLEGLAELRRATP--VPIAADES-LTSRA 246
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497478881 324 KLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRAGyTAVVSHRSGETedatiaDIAVATNA 387
Cdd:COG4948 247 DFRRLIEAGAVDIVNIKLSKVGGLTEALRIAALAEAHG-VPVMPHCMLES------GIGLAAAL 303
|
|
| NAAAR |
cd03317 |
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of ... |
281-400 |
1.22e-03 |
|
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239433 [Multi-domain] Cd Length: 354 Bit Score: 40.68 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 281 EFPILSIEDGLDENDWEGHKLLTDRIGGKVQLvgdDLFVTNTKKLAQGIEQGVGNSILIKVNQIGTLTETFEAIEMAKRA 360
Cdd:cd03317 202 EYGLLMIEQPLAADDLIDHAELQKLLKTPICL---DESIQSAEDARKAIELGACKIINIKPGRVGGLTEALKIHDLCQEH 278
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 497478881 361 GYTAVVshrsG---ETEDATIADIAVATNAGQIKTGSMSRTDR 400
Cdd:cd03317 279 GIPVWC----GgmlESGIGRAHNVALASLPNFTYPGDISASSR 317
|
|
| MR_like |
cd03316 |
Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup ... |
71-136 |
3.67e-03 |
|
Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues, a Lys-X-Lys motif and a conserved histidine-aspartate dyad. Members of the MR subgroup are mandelate racemase, D-glucarate/L-idarate dehydratase (GlucD), D-altronate/D-mannonate dehydratase , D-galactonate dehydratase (GalD) , D-gluconate dehydratase (GlcD), and L-rhamnonate dehydratase (RhamD).
Pssm-ID: 239432 [Multi-domain] Cd Length: 357 Bit Score: 39.13 E-value: 3.67e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497478881 71 VNNLISEAIIGMDVTDqvgIDRTMIEL-DGTENKGKLG--ANAILGVSMACAHAAAESVGLPLYRYLGG 136
Cdd:cd03316 56 IEDLLAPLLIGRDPLD---IERLWEKLyRRLFWRGRGGvaMAAISAVDIALWDIKGKAAGVPVYKLLGG 121
|
|
| MLE |
cd03318 |
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis, ... |
21-143 |
7.05e-03 |
|
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis,cis-muconate (CCM) to muconolactone (ML) in the catechol branch of the beta-ketoadipate pathway. This pathway is used in soil microbes to breakdown lignin-derived aromatics, catechol and protocatechuate, to citric acid cycle intermediates. Some bacterial species are also capable of dehalogenating chloroaromatic compounds by the action of chloromuconate lactonizing enzymes (Cl-MLEs). MLEs are members of the enolase superfamily characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and that is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239434 [Multi-domain] Cd Length: 365 Bit Score: 38.45 E-value: 7.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497478881 21 VEVEVLTESGF--FGRAIVPSGASTGEhEAVElrdgdksrylgkGVQNAVDNVnnlISEAIIGMDVTDQVGIdrtMIELD 98
Cdd:cd03318 31 VLVRLTTSDGVvgIGEATTPGGPAWGG-ESPE------------TIKAIIDRY---LAPLLIGRDATNIGAA---MALLD 91
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 497478881 99 GTEnKGKLGANAilGVSMACAHAAAESVGLPLYRYLGGFNAKQLP 143
Cdd:cd03318 92 RAV-AGNLFAKA--AIEMALLDAQGRRLGLPVSELLGGRVRDSLP 133
|
|
| |
