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Conserved domains on  [gi|497481991|ref|WP_009796189|]
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S-adenosylmethionine:tRNA ribosyltransferase-isomerase, partial [Bacillus sp. NRRL B-14911]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
QueA super family cl43278
S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) [Translation, ...
 1-74 2.37e-56

S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) is part of the Pathway/BioSystem: tRNA modification


The actual alignment was detected with superfamily member COG0809:

Pssm-ID: 440571 [Multi-domain]  Cd Length: 340  Bit Score: 175.59  E-value: 2.37e-56
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497481991   1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLII 74
Cdd:COG0809  267 GTLKPFSGWTDIFIYPGYRFKVVDALITNFHLPKSTLLMLVSAFAGRELIMAAYQHAIEEKYRFFSYGDAMLIL 340
 
Name Accession Description Interval E-value
QueA COG0809
S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) [Translation, ...
 1-74 2.37e-56

S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440571 [Multi-domain]  Cd Length: 340  Bit Score: 175.59  E-value: 2.37e-56
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497481991   1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLII 74
Cdd:COG0809  267 GTLKPFSGWTDIFIYPGYRFKVVDALITNFHLPKSTLLMLVSAFAGRELIMAAYQHAIEEKYRFFSYGDAMLIL 340
queA PRK00147
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional
 1-74 2.53e-55

S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional


Pssm-ID: 234666 [Multi-domain]  Cd Length: 342  Bit Score: 172.95  E-value: 2.53e-55
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497481991   1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLII 74
Cdd:PRK00147 269 GELKPFSGWTDIFIYPGYRFKVVDALITNFHLPKSTLLMLVSAFAGRERILAAYKHAVAEKYRFFSYGDAMLIL 342
Queuosine_synth pfam02547
Queuosine biosynthesis protein; Queuosine (Q) biosynthesis protein, or S-adenosylmethionine: ...
 1-73 8.05e-55

Queuosine biosynthesis protein; Queuosine (Q) biosynthesis protein, or S-adenosylmethionine:tRNA -ribosyltransferase-isomerase, is required for the synthesis of the queuosine precursor (oQ). It catalyzes the transfer and isomerization of the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to form epoxyqueuosine (oQ-tRNA). Q is a hypermodified nucleoside usually found at the first position of the anticodon of asparagine, aspartate, histidine, and tyrosine tRNAs. In Streptococcus gordonii, QueA has been shown to play a role in the regulation of arginine deiminase genes.


Pssm-ID: 460587 [Multi-domain]  Cd Length: 336  Bit Score: 171.79  E-value: 8.05e-55
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497481991    1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLI 73
Cdd:pfam02547 264 GAAKPFSGWTDIFIYPGYRFKVVDALITNFHLPKSTLLMLVSAFAGRELVMAAYREAVEEGYRFFSYGDAMLI 336
queA TIGR00113
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; This model describes the enzyme for ...
 1-74 2.58e-42

S-adenosylmethionine:tRNA ribosyltransferase-isomerase; This model describes the enzyme for S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA). QueA synthesizes Queuosine which is usually in the first position of the anticodon of tRNAs specific for asparagine, aspartate, histidine, and tyrosine. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272912 [Multi-domain]  Cd Length: 344  Bit Score: 139.90  E-value: 2.58e-42
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497481991    1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLII 74
Cdd:TIGR00113 271 GLIEPFFGDTSIFIYPGYQFKVVDGLITNFHLPKSSLIMLVSALAGRENTMNAYKHAVEEKYRFFSYGDAMLIL 344
 
Name Accession Description Interval E-value
QueA COG0809
S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) [Translation, ...
 1-74 2.37e-56

S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440571 [Multi-domain]  Cd Length: 340  Bit Score: 175.59  E-value: 2.37e-56
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497481991   1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLII 74
Cdd:COG0809  267 GTLKPFSGWTDIFIYPGYRFKVVDALITNFHLPKSTLLMLVSAFAGRELIMAAYQHAIEEKYRFFSYGDAMLIL 340
queA PRK00147
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional
 1-74 2.53e-55

S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional


Pssm-ID: 234666 [Multi-domain]  Cd Length: 342  Bit Score: 172.95  E-value: 2.53e-55
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497481991   1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLII 74
Cdd:PRK00147 269 GELKPFSGWTDIFIYPGYRFKVVDALITNFHLPKSTLLMLVSAFAGRERILAAYKHAVAEKYRFFSYGDAMLIL 342
Queuosine_synth pfam02547
Queuosine biosynthesis protein; Queuosine (Q) biosynthesis protein, or S-adenosylmethionine: ...
 1-73 8.05e-55

Queuosine biosynthesis protein; Queuosine (Q) biosynthesis protein, or S-adenosylmethionine:tRNA -ribosyltransferase-isomerase, is required for the synthesis of the queuosine precursor (oQ). It catalyzes the transfer and isomerization of the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to form epoxyqueuosine (oQ-tRNA). Q is a hypermodified nucleoside usually found at the first position of the anticodon of asparagine, aspartate, histidine, and tyrosine tRNAs. In Streptococcus gordonii, QueA has been shown to play a role in the regulation of arginine deiminase genes.


Pssm-ID: 460587 [Multi-domain]  Cd Length: 336  Bit Score: 171.79  E-value: 8.05e-55
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497481991    1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLI 73
Cdd:pfam02547 264 GAAKPFSGWTDIFIYPGYRFKVVDALITNFHLPKSTLLMLVSAFAGRELVMAAYREAVEEGYRFFSYGDAMLI 336
queA TIGR00113
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; This model describes the enzyme for ...
 1-74 2.58e-42

S-adenosylmethionine:tRNA ribosyltransferase-isomerase; This model describes the enzyme for S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA). QueA synthesizes Queuosine which is usually in the first position of the anticodon of tRNAs specific for asparagine, aspartate, histidine, and tyrosine. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272912 [Multi-domain]  Cd Length: 344  Bit Score: 139.90  E-value: 2.58e-42
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497481991    1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLII 74
Cdd:TIGR00113 271 GLIEPFFGDTSIFIYPGYQFKVVDGLITNFHLPKSSLIMLVSALAGRENTMNAYKHAVEEKYRFFSYGDAMLIL 344
PRK01424 PRK01424
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional
 1-73 6.79e-22

S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional


Pssm-ID: 234954  Cd Length: 366  Bit Score: 86.12  E-value: 6.79e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497481991   1 GRLEAGSGWTSIFIYPGYEFKAIDGMITNFHLPKSTLIMLISALAGRENVLNAYNEAVKERYRFFSFGDAMLI 73
Cdd:PRK01424 290 GIVKAGSFETDIFITPGFKFQTADMLLTNFHFPKSTLFMLICAFAGFKEMHELYKYAIKEKMRFFSYGDATLL 362
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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