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Conserved domains on  [gi|497531342|ref|WP_009845540|]
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MULTISPECIES: AraC family transcriptional regulator [Vibrio]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 12204073)

AraC family transcriptional regulator containing an AraC family helix-turn-helix (HTH) DNA-binding domain, may regulate the expression of genes with diverse biological functions including metabolism, stress response, and virulence

CATH:  1.10.10.10
Gene Ontology:  GO:0003677|GO:0006355|GO:0003700
PubMed:  33837749|12596232|10473770|15808743|9409145|11282467

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YdeE COG3708
Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription] ...
 136-299 1.59e-31

Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription];


:

Pssm-ID: 442922  Cd Length: 157  Bit Score: 115.12  E-value: 1.59e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342 136 EVRIDERESFLVKGMTSEISGLFSltqDFAQKVPQLWSRL--EGEVEIPD-ANMLQFIGVVdlTQSCFDGTNIYYWAGVE 212
Cdd:COG3708    2 EYRIVEKPAFKLVGLSARTSNSDE---EANEEIPALWQRFlpEGLAEIPNlSNPGGLYGVC--TDYESDEGEFDYLAGVE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342 213 LHDEISIPqlpsiisDKLEVLTIPKQTYAVVKHRGPI-EHLPHTLSWFVLNWLPNSGYRGVDGYELEMYPFGYQAHaSDA 291
Cdd:COG3708   77 VSSFDEVP-------EGLETLEIPAGTYAVFTHKGPMpEALQETWQYIYSEWLPSSGYERADGPDFEVYDERDDPS-PDS 148


                 ....*...
gi 497531342 292 EMEYWVPI 299
Cdd:COG3708  149 EVEIWIPI 156
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
24-106 4.58e-29

helix_turn_helix, arabinose operon control protein;


:

Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 106.10  E-value: 4.58e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342    24 LSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNSEISFSRSFKQMFGVSPS 103
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 497531342   104 QYR 106
Cdd:smart00342  82 EYR 84
 
Name Accession Description Interval E-value
YdeE COG3708
Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription] ...
 136-299 1.59e-31

Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription];


Pssm-ID: 442922  Cd Length: 157  Bit Score: 115.12  E-value: 1.59e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342 136 EVRIDERESFLVKGMTSEISGLFSltqDFAQKVPQLWSRL--EGEVEIPD-ANMLQFIGVVdlTQSCFDGTNIYYWAGVE 212
Cdd:COG3708    2 EYRIVEKPAFKLVGLSARTSNSDE---EANEEIPALWQRFlpEGLAEIPNlSNPGGLYGVC--TDYESDEGEFDYLAGVE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342 213 LHDEISIPqlpsiisDKLEVLTIPKQTYAVVKHRGPI-EHLPHTLSWFVLNWLPNSGYRGVDGYELEMYPFGYQAHaSDA 291
Cdd:COG3708   77 VSSFDEVP-------EGLETLEIPAGTYAVFTHKGPMpEALQETWQYIYSEWLPSSGYERADGPDFEVYDERDDPS-PDS 148


                 ....*...
gi 497531342 292 EMEYWVPI 299
Cdd:COG3708  149 EVEIWIPI 156
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
24-106 4.58e-29

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 106.10  E-value: 4.58e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342    24 LSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNSEISFSRSFKQMFGVSPS 103
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 497531342   104 QYR 106
Cdd:smart00342  82 EYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
5-111 8.26e-29

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 111.03  E-value: 8.26e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   5 AFDRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGF 84
Cdd:COG2207  150 LLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGF 229

                         90       100
                 ....*....|....*....|....*..
gi 497531342  85 NSEISFSRSFKQMFGVSPSQYRKAGKR 111
Cdd:COG2207  230 SSQSHFSRAFKKRFGVTPSEYRKRLRA 256
HTH_18 pfam12833
Helix-turn-helix domain;
29-108 2.33e-24

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 93.81  E-value: 2.33e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   29 LATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDR-VIDIALGLGFNSEISFSRSFKQMFGVSPSQYRK 107
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEDTGLsVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 497531342  108 A 108
Cdd:pfam12833  81 R 81
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
7-108 4.75e-21

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 86.13  E-value: 4.75e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   7 DRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNS 86
Cdd:PRK10219   5 KIIQTLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVS 84

                         90       100
                 ....*....|....*....|..
gi 497531342  87 EISFSRSFKQMFGVSPSQYRKA 108
Cdd:PRK10219  85 QQTFSRVFRRQFDRTPSDYRHR 106
AraC_E_bind smart00871
Bacterial transcription activator, effector binding domain; This domain is found in the ...
 136-299 2.38e-19

Bacterial transcription activator, effector binding domain; This domain is found in the probable effector binding domain of a number of different bacterial transcription activators.and is also present in some DNA gyrase inhibitors. The absence of a HTH motif in the DNA gyrase inhibitors is thought to indicate the fact that these do not bind DNA.


Pssm-ID: 214874 [Multi-domain]  Cd Length: 158  Bit Score: 82.91  E-value: 2.38e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   136 EVRIDERESFLVKGMTSEISglfsltqDFAQKVPQLWSRLEGEVE----IPDANMLQFIGVVDLTQSCFDGTNIYYWAGV 211
Cdd:smart00871   1 EVRIVELPAFKVAGLRHRGP-------NEDEKIPELWQRLIQWAKelglLPVGNSGEPYGVYYDDPDDTPDGEFRYDAGV 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   212 ELHDEISIPqlpsiisDKLEVLTIPKQTYAVVKHRGPI-EHLPHTLSWFVLNWLPNSGY-RGVDGYELEMYPFGYQAHAS 289
Cdd:smart00871  74 EVSDEVEAP-------EGVETKTIPAGKYAVFTHKGGSyDEIQEAWEAIYGEWLPNSGYeLRDAGPDFEVYLNDPPDTDP 146

                          170
                   ....*....|.
gi 497531342   290 -DAEMEYWVPI 299
Cdd:smart00871 147 eELVTEIYIPV 157
adjacent_YSIRK TIGR04094
YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only ...
 9-106 6.38e-16

YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.


Pssm-ID: 274977 [Multi-domain]  Cd Length: 383  Bit Score: 77.41  E-value: 6.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342    9 ISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSqAAEELLDGKDRVIDIALGLGFNSEI 88
Cdd:TIGR04094 287 IRAVIQYINLNLYDPLKVEEIAKQFFMSESKLRKLFKKEMGISIQEYISKRKIE-EAKYLLRSQIPVSEVSNELGFYDLS 365

                          90
                  ....*....|....*...
gi 497531342   89 SFSRSFKQMFGVSPSQYR 106
Cdd:TIGR04094 366 HFSRTFKKHTGVSPKQYQ 383
GyrI-like pfam06445
GyrI-like small molecule binding domain; This family contains the small molecule binding ...
 136-299 8.56e-16

GyrI-like small molecule binding domain; This family contains the small molecule binding domain of a number of different bacterial transcription activators. This family also contains DNA gyrase inhibitors. The GyrI superfamily contains a diad of the SHS2 module, adapted for small-molecule binding. The GyrI superfamily includes a family of secreted forms that is found only in animals and the bacterial pathogen Leptospira.


Pssm-ID: 428947  Cd Length: 153  Bit Score: 73.21  E-value: 8.56e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  136 EVRIDERESFLVKGMTSEisGLFSLTQdfaqkVPQLWSRLEGEV---EIPDANMlQFIGVVDLTQSCFDGTNIYYWAGVE 212
Cdd:pfam06445   1 EVEIVELPAFRVAGLRHR--GPYNEEG-----IGALWEELCAWAsenGLSPAPS-PLIGVSYDDPEVTEDEELRYDAGVA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  213 LHDEISIPqlpsiisDKLEVLTIPKQTYAVVKHRGPIEHLPHTLSWFVLNWLPNSGYRGVDGYELEMY-PFGYQAHASDA 291
Cdd:pfam06445  73 VPIPVEGP-------EGVEELELPGGEYAVFRHKGPYDDLQETYAKIYGEWLPESGYERRDGPSFEIYlNDPREVPEEEL 145


                  ....*...
gi 497531342  292 EMEYWVPI 299
Cdd:pfam06445 146 KTEIYIPV 153
 
Name Accession Description Interval E-value
YdeE COG3708
Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription] ...
 136-299 1.59e-31

Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription];


Pssm-ID: 442922  Cd Length: 157  Bit Score: 115.12  E-value: 1.59e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342 136 EVRIDERESFLVKGMTSEISGLFSltqDFAQKVPQLWSRL--EGEVEIPD-ANMLQFIGVVdlTQSCFDGTNIYYWAGVE 212
Cdd:COG3708    2 EYRIVEKPAFKLVGLSARTSNSDE---EANEEIPALWQRFlpEGLAEIPNlSNPGGLYGVC--TDYESDEGEFDYLAGVE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342 213 LHDEISIPqlpsiisDKLEVLTIPKQTYAVVKHRGPI-EHLPHTLSWFVLNWLPNSGYRGVDGYELEMYPFGYQAHaSDA 291
Cdd:COG3708   77 VSSFDEVP-------EGLETLEIPAGTYAVFTHKGPMpEALQETWQYIYSEWLPSSGYERADGPDFEVYDERDDPS-PDS 148


                 ....*...
gi 497531342 292 EMEYWVPI 299
Cdd:COG3708  149 EVEIWIPI 156
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
24-106 4.58e-29

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 106.10  E-value: 4.58e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342    24 LSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNSEISFSRSFKQMFGVSPS 103
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 497531342   104 QYR 106
Cdd:smart00342  82 EYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
5-111 8.26e-29

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 111.03  E-value: 8.26e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   5 AFDRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGF 84
Cdd:COG2207  150 LLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGF 229

                         90       100
                 ....*....|....*....|....*..
gi 497531342  85 NSEISFSRSFKQMFGVSPSQYRKAGKR 111
Cdd:COG2207  230 SSQSHFSRAFKKRFGVTPSEYRKRLRA 256
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 7-108 8.31e-29

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 112.17  E-value: 8.31e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   7 DRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNS 86
Cdd:COG4977  210 PRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGS 289

                         90       100
                 ....*....|....*....|..
gi 497531342  87 EISFSRSFKQMFGVSPSQYRKA 108
Cdd:COG4977  290 ASHFRRAFRRRFGVSPSAYRRR 311
HTH_18 pfam12833
Helix-turn-helix domain;
29-108 2.33e-24

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 93.81  E-value: 2.33e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   29 LATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDR-VIDIALGLGFNSEISFSRSFKQMFGVSPSQYRK 107
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEDTGLsVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 497531342  108 A 108
Cdd:pfam12833  81 R 81
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 7-114 2.07e-23

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 98.20  E-value: 2.07e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   7 DRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLsQAAEELLDGKDRVIDIALGLGFNS 86
Cdd:COG2169   84 DLVARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRL-LRARQLLQTGLSVTDAAYAAGFGS 162

                         90       100
                 ....*....|....*....|....*...
gi 497531342  87 EISFSRSFKQMFGVSPSQYRKAGKRVGL 114
Cdd:COG2169  163 LSRFYEAFKKLLGMTPSAYRRGGAGAAI 190
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
7-108 4.75e-21

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 86.13  E-value: 4.75e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   7 DRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNS 86
Cdd:PRK10219   5 KIIQTLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVS 84

                         90       100
                 ....*....|....*....|..
gi 497531342  87 EISFSRSFKQMFGVSPSQYRKA 108
Cdd:PRK10219  85 QQTFSRVFRRQFDRTPSDYRHR 106
PRK11511 PRK11511
MDR efflux pump AcrAB transcriptional activator MarA;
9-106 1.52e-20

MDR efflux pump AcrAB transcriptional activator MarA;


Pssm-ID: 236920 [Multi-domain]  Cd Length: 127  Bit Score: 85.15  E-value: 1.52e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   9 ISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNSEI 88
Cdd:PRK11511  11 IHSILDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQ 90

                         90
                 ....*....|....*...
gi 497531342  89 SFSRSFKQMFGVSPSQYR 106
Cdd:PRK11511  91 TLTRTFKNYFDVPPHKYR 108
SbmC COG3449
DNA gyrase inhibitor GyrI/SbmC [Replication, recombination and repair];
7-299 3.54e-20

DNA gyrase inhibitor GyrI/SbmC [Replication, recombination and repair];


Pssm-ID: 442672 [Multi-domain]  Cd Length: 286  Bit Score: 87.99  E-value: 3.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   7 DRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNS 86
Cdd:COG3449   13 RRILLVLIALHDDLDLLLLALLLAFAFHFFFFHRRRRFRALIGRRARLLLRRRLLAALALLLLSSSAIIAAAAAASGYSS 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  87 EISFSRSFKQMFGVSPSQYRKAGKRVGLKKPIQvsetasnsENRALSFVEVRIDERESFLVKGMTSEisGLFsltqdfaQ 166
Cdd:COG3449   93 SASFRRFFRAFGGSSRSRRRRAKAKLLALPPLD--------PPRLEPMMDVEIKELPPRRVAYLRHR--GPY-------E 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342 167 KVPQLWSRLEGEVE---IPDANmLQFIGV-------VDLTQSCFDgtniyywAGVELHDEISIPQLpsiisdkLEVLTIP 236
Cdd:COG3449  156 EIGEAFERLIAWAKargLLPPD-SRTIGIyyddpdiTPPEKLRYD-------ACVTVPEDVALPGG-------VEVKTIP 220

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497531342 237 KQTYAVVKHRGPIEHLPHTLSWFVLNWLPNSGYRGVDGYELEMYP-FGYQAHASDAEMEYWVPI 299
Cdd:COG3449  221 GGRYAVLRHKGPYEDLGAAWDWLYGEWLPASGYELRDRPCFEIYLnDPRETPEGELITDIYLPL 284
AraC_E_bind smart00871
Bacterial transcription activator, effector binding domain; This domain is found in the ...
 136-299 2.38e-19

Bacterial transcription activator, effector binding domain; This domain is found in the probable effector binding domain of a number of different bacterial transcription activators.and is also present in some DNA gyrase inhibitors. The absence of a HTH motif in the DNA gyrase inhibitors is thought to indicate the fact that these do not bind DNA.


Pssm-ID: 214874 [Multi-domain]  Cd Length: 158  Bit Score: 82.91  E-value: 2.38e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   136 EVRIDERESFLVKGMTSEISglfsltqDFAQKVPQLWSRLEGEVE----IPDANMLQFIGVVDLTQSCFDGTNIYYWAGV 211
Cdd:smart00871   1 EVRIVELPAFKVAGLRHRGP-------NEDEKIPELWQRLIQWAKelglLPVGNSGEPYGVYYDDPDDTPDGEFRYDAGV 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   212 ELHDEISIPqlpsiisDKLEVLTIPKQTYAVVKHRGPI-EHLPHTLSWFVLNWLPNSGY-RGVDGYELEMYPFGYQAHAS 289
Cdd:smart00871  74 EVSDEVEAP-------EGVETKTIPAGKYAVFTHKGGSyDEIQEAWEAIYGEWLPNSGYeLRDAGPDFEVYLNDPPDTDP 146

                          170
                   ....*....|.
gi 497531342   290 -DAEMEYWVPI 299
Cdd:smart00871 147 eELVTEIYIPV 157
PRK15121 PRK15121
MDR efflux pump AcrAB transcriptional activator RobA;
9-122 2.42e-16

MDR efflux pump AcrAB transcriptional activator RobA;


Pssm-ID: 185076 [Multi-domain]  Cd Length: 289  Bit Score: 77.36  E-value: 2.42e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   9 ISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNSEI 88
Cdd:PRK15121   7 IRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKAAVALRLTSRPILDIALQYRFDSQQ 86

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 497531342  89 SFSRSFKQMFGVSPSQYRKAG--KRVGLKKPIQVSE 122
Cdd:PRK15121  87 TFTRAFKKQFAQTPALYRRSPewSAFGIRPPIRLGE 122
ftrA PRK09393
transcriptional activator FtrA; Provisional
 7-107 3.43e-16

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 77.31  E-value: 3.43e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   7 DRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNS 86
Cdd:PRK09393 218 DRLGPLIDWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQIAERAGFGS 297

                         90       100
                 ....*....|....*....|.
gi 497531342  87 EISFSRSFKQMFGVSPSQYRK 107
Cdd:PRK09393 298 EESLRHHFRRRAATSPAAYRK 318
adjacent_YSIRK TIGR04094
YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only ...
 9-106 6.38e-16

YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.


Pssm-ID: 274977 [Multi-domain]  Cd Length: 383  Bit Score: 77.41  E-value: 6.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342    9 ISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSqAAEELLDGKDRVIDIALGLGFNSEI 88
Cdd:TIGR04094 287 IRAVIQYINLNLYDPLKVEEIAKQFFMSESKLRKLFKKEMGISIQEYISKRKIE-EAKYLLRSQIPVSEVSNELGFYDLS 365

                          90
                  ....*....|....*...
gi 497531342   89 SFSRSFKQMFGVSPSQYR 106
Cdd:TIGR04094 366 HFSRTFKKHTGVSPKQYQ 383
GyrI-like pfam06445
GyrI-like small molecule binding domain; This family contains the small molecule binding ...
 136-299 8.56e-16

GyrI-like small molecule binding domain; This family contains the small molecule binding domain of a number of different bacterial transcription activators. This family also contains DNA gyrase inhibitors. The GyrI superfamily contains a diad of the SHS2 module, adapted for small-molecule binding. The GyrI superfamily includes a family of secreted forms that is found only in animals and the bacterial pathogen Leptospira.


Pssm-ID: 428947  Cd Length: 153  Bit Score: 73.21  E-value: 8.56e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  136 EVRIDERESFLVKGMTSEisGLFSLTQdfaqkVPQLWSRLEGEV---EIPDANMlQFIGVVDLTQSCFDGTNIYYWAGVE 212
Cdd:pfam06445   1 EVEIVELPAFRVAGLRHR--GPYNEEG-----IGALWEELCAWAsenGLSPAPS-PLIGVSYDDPEVTEDEELRYDAGVA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  213 LHDEISIPqlpsiisDKLEVLTIPKQTYAVVKHRGPIEHLPHTLSWFVLNWLPNSGYRGVDGYELEMY-PFGYQAHASDA 291
Cdd:pfam06445  73 VPIPVEGP-------EGVEELELPGGEYAVFRHKGPYDDLQETYAKIYGEWLPESGYERRDGPSFEIYlNDPREVPEEEL 145


                  ....*...
gi 497531342  292 EMEYWVPI 299
Cdd:pfam06445 146 KTEIYIPV 153
Cass2 pfam14526
Integron-associated effector binding protein; This family contains Cass2 from Vibrio cholerae, ...
 138-299 5.42e-15

Integron-associated effector binding protein; This family contains Cass2 from Vibrio cholerae, an integron-associated protein that has been shown to bind cationic drug compounds with submicromolar affinity. Cass2 has been proposed to be representative of a larger family of independent effector-binding proteins associated with lateral gene transfer within Vibrio and other closely-related species.


Pssm-ID: 434016 [Multi-domain]  Cd Length: 149  Bit Score: 70.85  E-value: 5.42e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  138 RIDERESFLVKGMTSEISglFSLTQDFAQKvPQLWSRLEGEVEIPD-ANMLQFIGVVdlTQSCFDGTNIYYWAGVELHDE 216
Cdd:pfam14526   1 EIVELPSFTVAGIRYEGP--NEYEDHNKEI-GKFWEEFNEDGRLPNiKKDDKSYGIY--VDYEDEENEFDYYAGVEVPSF 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  217 ISIPqlpsiisDKLEVLTIPKQTYAVVKHRGPI-EHLPHTLSWFVLNWLPNSGYRGVDGYELEMYPfgyQAHASDAEMEY 295
Cdd:pfam14526  76 SELP-------EGLVVIEIPGGKYAVFTIEGDFpDAIAEAWTRIYGWLLPNSGYERAGGPDFEVYK---ENGDENMKIEL 145


                  ....
gi 497531342  296 WVPI 299
Cdd:pfam14526 146 YIPV 149
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 10-107 1.30e-13

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 69.67  E-value: 1.30e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  10 SRVLAYIHANLSS-ALSLEDLATQSCWSRWQLQRVFqAETGLTVANYVRELKLSQAAEELL-DGKDRVI-DIALGLGFNS 86
Cdd:PRK09685 200 QKVVALIDQSIQEeILRPEWIAGELGISVRSLYRLF-AEQGLVVAQYIRNRRLDRCADDLRpAADDEKItSIAYKWGFSD 278

                         90       100
                 ....*....|....*....|.
gi 497531342  87 EISFSRSFKQMFGVSPSQYRK 107
Cdd:PRK09685 279 SSHFSTAFKQRFGVSPGEYRR 299
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
4-107 3.96e-10

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 59.60  E-value: 3.96e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   4 PAFD-RISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGL 82
Cdd:PRK10572 179 PPMDpRVREACQYISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNV 258

                         90       100
                 ....*....|....*....|....*
gi 497531342  83 GFNSEISFSRSFKQMFGVSPSQYRK 107
Cdd:PRK10572 259 GYDDQLYFSRVFKKCTGASPSEFRA 283
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
8-106 4.44e-10

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 59.31  E-value: 4.44e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   8 RISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNSE 87
Cdd:PRK13503 172 RLNQLLAWLEDHFAEEVNWEALADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCGFGDS 251

                         90
                 ....*....|....*....
gi 497531342  88 ISFSRSFKQMFGVSPSQYR 106
Cdd:PRK13503 252 NHFSTLFRREFSWSPRDIR 270
PRK10371 PRK10371
transcriptional regulator MelR;
1-108 7.29e-10

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 58.68  E-value: 7.29e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   1 MNTPAFDRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIAL 80
Cdd:PRK10371 185 VSRHAQFYVSQMLGFIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIAL 264

                         90       100
                 ....*....|....*....|....*...
gi 497531342  81 GLGFNSEISFSRSFKQMFGVSPSQYRKA 108
Cdd:PRK10371 265 TAGFRSSSRFYSTFGKYVGMSPQQYRKL 292
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
4-107 7.21e-09

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 55.68  E-value: 7.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   4 PAFDRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLG 83
Cdd:PRK13501 173 PDGEQLDLIMSALQQSLGAYFDMADFCHKNQLVERSLKQLFRQQTGMSISHYLRQIRLCHAKCLLRGSEHRISDIAARCG 252

                         90       100
                 ....*....|....*....|....
gi 497531342  84 FNSEISFSRSFKQMFGVSPSQYRK 107
Cdd:PRK13501 253 FEDSNYFSAVFTREAGMTPRDYRQ 276
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
6-106 1.44e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 51.59  E-value: 1.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   6 FDRISRVLAyihANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFN 85
Cdd:PRK13502 178 LDKLITALA---NSLECPFALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCGFE 254

                         90       100
                 ....*....|....*....|.
gi 497531342  86 SEISFSRSFKQMFGVSPSQYR 106
Cdd:PRK13502 255 DSNYFSVVFTRETGMTPSQWR 275
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
9-106 2.66e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 51.26  E-value: 2.66e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   9 ISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNSEI 88
Cdd:PRK13500 208 LDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSN 287

                         90
                 ....*....|....*...
gi 497531342  89 SFSRSFKQMFGVSPSQYR 106
Cdd:PRK13500 288 YFSVVFTRETGMTPSQWR 305
PRK15435 PRK15435
bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;
22-115 3.56e-07

bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;


Pssm-ID: 185333 [Multi-domain]  Cd Length: 353  Bit Score: 50.95  E-value: 3.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  22 SALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKlSQAAEELLDGKDRVIDIALGLGFNSEISFSRSFKQMFGVS 101
Cdd:PRK15435  98 TPVTLEALADQVAMSPFHLHRLFKATTGMTPKAWQQAWR-ARRLREALAKGESVTTSILNAGFPDSSSYYRKADETLGMT 176

                         90
                 ....*....|....
gi 497531342 102 PSQYRKAGKRVGLK 115
Cdd:PRK15435 177 AKQFRHGGENLAVR 190
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 66-107 2.87e-05

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 40.60  E-value: 2.87e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 497531342   66 EELLDGKDRVIDIALGLGFNSEiSFSRSFKQMFGVSPSQYRK 107
Cdd:pfam00165   2 RENLSTNLTIADIADELGFSRS-YFSRLFKKYTGVTPSQYRH 42
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 16-57 1.62e-04

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 38.29  E-value: 1.62e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 497531342   16 IHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVR 57
Cdd:pfam00165   1 LRENLSTNLTIADIADELGFSRSYFSRLFKKYTGVTPSQYRH 42
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 11-107 4.09e-04

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 41.52  E-value: 4.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342  11 RVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFqAETGLTVANYVRELKLSQAAEELLDGKDRVIDIALGLGFNSEISF 90
Cdd:PRK15185 210 RVYNIISSSPSRQWKLTDVADHIFMSTSTLKRKL-AEEGTSFSDIYLSARMNQAAKLLRIGNHNVNAVALKCGYDSTSYF 288

                         90
                 ....*....|....*..
gi 497531342  91 SRSFKQMFGVSPSQYRK 107
Cdd:PRK15185 289 IQCFKKYFKTTPSTFIK 305
BltR2 COG4978
GyrI-like small molecule binding domain [Signal transduction mechanisms];
137-294 7.32e-04

GyrI-like small molecule binding domain [Signal transduction mechanisms];


Pssm-ID: 444003  Cd Length: 144  Bit Score: 39.21  E-value: 7.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342 137 VRIDERESFLVKGMTSEISglfslTQDFAQKVPQLWSRLEGEVEipdANMLQFIGVVDLTQSCFDGTNIYYWAGVELHDE 216
Cdd:COG4978    1 VEVKELPAQPVASIRATVP-----MDELGELIGEAFGELFAYLA---ENGIEPAGPPFAIYHDTDEDDVDVEVGVPVAGP 72

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497531342 217 ISIPqlpsiisDKLEVLTIPKQTYAVVKHRGPIEHLPHTLSwFVLNWLPNSGYRgVDGYELEMYPFGYQAHASDAEME 294
Cdd:COG4978   73 LPGT-------GDIKVGTLPAGKAATATHRGPYDTLDEAYE-ALLAWIEENGLE-VAGPPREVYLTDPGNEPDPEEWV 141
PRK10130 PRK10130
HTH-type transcriptional regulator EutR;
9-103 3.57e-03

HTH-type transcriptional regulator EutR;


Pssm-ID: 182258 [Multi-domain]  Cd Length: 350  Bit Score: 38.75  E-value: 3.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   9 ISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAETGLTVANYVRELKLSQAAEELLDGKDR---VIDIALGLGFN 85
Cdd:PRK10130 242 LSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNAFHAILGIGPNAWLKRIRLNAVRRELISPWSQsttVKDAAMQWGFW 321

                         90
                 ....*....|....*...
gi 497531342  86 SEISFSRSFKQMFGVSPS 103
Cdd:PRK10130 322 HLGQFATDYQQLFAEKPS 339
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 1-106 8.02e-03

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 37.21  E-value: 8.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531342   1 MNTPAFDRISRVLAYIHANLSSALSLEDLATQSCWSRWQLQRVFQAEtGLTVANYVRELKLSQAAEELLDGKDRVIDIAL 80
Cdd:PRK09978 136 LNVLQPNMRTRVCTVINNNIAHEWTLARIASELLMSPSLLKKKLREE-ETSYSQLLTECRMQRALQLIVIHGFSIKRVAV 214

                         90       100
                 ....*....|....*....|....*.
gi 497531342  81 GLGFNSEISFSRSFKQMFGVSPSQYR 106
Cdd:PRK09978 215 SCGYHSVSYFIYVFRNYYGMTPTEYQ 240
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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